{
	"name":"rfl02044",
	"children":[
	{
		"name":"Type I secretion system",
		"children":[
		{
			"name":"alpha-Hemolysin\/cyclolysin transporter",
			"children":[
			{
				"name":"Rmf_51590 ABC export transporter fused inner membrane and ATPases\tK11004 hlyB; ATP-binding cassette, subfamily B, bacterial HlyB\/CyaB"
			},
			{
				"name":"Rmf_51600 membrane-fusion protein\tK11003 hlyD; membrane fusion protein, hemolysin D"
			},
			{
				"name":"Rmf_26640 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_34360 cyaE; protein CyaE\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_35200 hypothetical protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"RTX toxin transporter",
			"children":[
			{
				"name":"Rmf_26640 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_34360 cyaE; protein CyaE\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_35200 hypothetical protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Multiple protein transporter",
			"children":[
			{
				"name":"Rmf_18730 hasD; transporter HasD\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"Rmf_18740 ABC transporter ATP-binding protein\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"Rmf_20980 peptidase\tK12536 hasD; ATP-binding cassette, subfamily C, type I secretion system permease\/ATPase"
			},
			{
				"name":"Rmf_18720 aprE_1; HlyD family type I secretion periplasmic adaptor subunit\tK12537 hasE; membrane fusion protein, type I secretion system"
			},
			{
				"name":"Rmf_20970 aprE_2; HlyD family type I secretion periplasmic adaptor subunit\tK12537 hasE; membrane fusion protein, type I secretion system"
			},
			{
				"name":"Rmf_26640 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_34360 cyaE; protein CyaE\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_35200 hypothetical protein\tK12340 tolC; outer membrane protein"
			}
			]
		},
		{
			"name":"Adhesin protein transporter"
		},
		{
			"name":"RaxAB-RaxC type I secretion system protein",
			"children":[
			{
				"name":"Rmf_26640 type I secretion protein TolC\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_34360 cyaE; protein CyaE\tK12340 tolC; outer membrane protein"
			},
			{
				"name":"Rmf_35200 hypothetical protein\tK12340 tolC; outer membrane protein"
			}
			]
		}
		]
	},
	{
		"name":"Type II secretion system",
		"children":[
		{
			"name":"General secretion pathway protein"
		},
		{
			"name":"Pilin secretion\/fimbrial assembly protein"
		},
		{
			"name":"Tight adherence (Tad) export apparatus",
			"children":[
			{
				"name":"Rmf_19640 prepilin peptidase\tK02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]"
			},
			{
				"name":"Rmf_31320 prepilin peptidase\tK02278 cpaA; prepilin peptidase CpaA [EC:3.4.23.43]"
			},
			{
				"name":"Rmf_19650 hypothetical protein\tK02279 cpaB; pilus assembly protein CpaB"
			},
			{
				"name":"Rmf_31310 hypothetical protein\tK02279 cpaB; pilus assembly protein CpaB"
			},
			{
				"name":"Rmf_19660 rhcC2; hypothetical protein\tK02280 cpaC; pilus assembly protein CpaC"
			},
			{
				"name":"Rmf_31300 hypothetical protein\tK02280 cpaC; pilus assembly protein CpaC"
			},
			{
				"name":"Rmf_19680 transcriptional regulator\tK02282 cpaE; pilus assembly protein CpaE"
			},
			{
				"name":"Rmf_31280 pilus assembly protein CpaE\tK02282 cpaE; pilus assembly protein CpaE"
			},
			{
				"name":"Rmf_19690 pilus assembly protein CpaF\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_31270 pilus assembly protein CpaF\tK02283 cpaF; pilus assembly protein CpaF [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_19700 hypothetical protein\tK12510 tadB; tight adherence protein B"
			},
			{
				"name":"Rmf_31260 hypothetical protein\tK12510 tadB; tight adherence protein B"
			},
			{
				"name":"Rmf_19710 fimbriae-related membrane protein\tK12511 tadC; tight adherence protein C"
			},
			{
				"name":"Rmf_31250 pilus assembly protein TadC\tK12511 tadC; tight adherence protein C"
			},
			{
				"name":"Rmf_19730 hypothetical protein\tK12513 tadE; tight adherence protein E"
			},
			{
				"name":"Rmf_19630 hypothetical protein\tK02651 flp; pilus assembly protein Flp\/PilA"
			},
			{
				"name":"Rmf_31330 hypothetical protein\tK02651 flp; pilus assembly protein Flp\/PilA"
			}
			]
		},
		{
			"name":"Toxin co-regulated pilus biosynthesis protein"
		},
		{
			"name":"MSHA pilus biogenesis protein"
		},
		{
			"name":"Type IVa pilus homolog protein",
			"children":[
			{
				"name":"Rmf_07630 membrane protein\tK02221 yggT; YggT family protein"
			}
			]
		},
		{
			"name":"Archaeal flagellar protein"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) core components"
		},
		{
			"name":"Competence-related DNA transformation transporter (DNA-T) related proteins"
		}
		]
	},
	{
		"name":"Type III secretion system",
		"children":[
		{
			"name":"Type III secretion core apparatus"
		},
		{
			"name":"Type III secretion related proteins"
		},
		{
			"name":"Flagellar export apparatus",
			"children":[
			{
				"name":"Rmf_35100 flhA; flagellar biosynthesis protein FlhA\tK02400 flhA; flagellar biosynthesis protein FlhA"
			},
			{
				"name":"Rmf_29350 flhB; flagellar biosynthesis protein FlhB\tK02401 flhB; flagellar biosynthesis protein FlhB"
			},
			{
				"name":"Rmf_35050 flagellar M-ring protein\tK02409 fliF; flagellar M-ring protein FliF"
			},
			{
				"name":"Rmf_35070 hypothetical protein\tK02411 fliH; flagellar assembly protein FliH"
			},
			{
				"name":"Rmf_48960 fliI; flagellum-specific ATP synthase\tK02412 fliI; flagellum-specific ATP synthase [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_35080 hypothetical protein\tK02417 fliN; flagellar motor switch protein FliN"
			},
			{
				"name":"Rmf_29420 hypothetical protein\tK02418 fliO; flagellar protein FliO\/FliZ"
			},
			{
				"name":"Rmf_29430 fliP; flagellar biosynthetic protein FliP\tK02419 fliP; flagellar biosynthesis protein FliP"
			},
			{
				"name":"Rmf_29370 fliQ; flagellar export apparatus protein FliQ\tK02420 fliQ; flagellar biosynthesis protein FliQ"
			},
			{
				"name":"Rmf_29360 flagellar biosynthetic protein FliR\tK02421 fliR; flagellar biosynthesis protein FliR"
			}
			]
		}
		]
	},
	{
		"name":"Type IV secretion system",
		"children":[
		{
			"name":"Conjugal DNA-protein transfer (VirB\/D) protein"
		},
		{
			"name":"DNA uptake competence system protein"
		},
		{
			"name":"Conjugal transfer pilus assembly protein"
		},
		{
			"name":"Pertussis toxin exporter"
		},
		{
			"name":"Cag pathogenicity island (PAI) protein"
		},
		{
			"name":"Icm\/Dot secretion system protein"
		},
		{
			"name":"Trb secretion system protein",
			"children":[
			{
				"name":"Rmf_15580 trbB_1; P-type conjugative transfer ATPase TrbB\tK20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_43540 trbB_2; P-type conjugative transfer ATPase TrbB\tK20527 trbB; type IV secretion system protein TrbB [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_15590 conjugal transfer protein TrbC\tK20528 trbC; type IV secretion system protein TrbC"
			},
			{
				"name":"Rmf_43550 conjugal transfer protein TrbC\tK20528 trbC; type IV secretion system protein TrbC"
			},
			{
				"name":"Rmf_15600 conjugal transfer protein\tK20529 trbD; type IV secretion system protein TrbD"
			},
			{
				"name":"Rmf_43560 conjugal transfer protein\tK20529 trbD; type IV secretion system protein TrbD"
			},
			{
				"name":"Rmf_15610 conjugal transfer protein TrbE\tK20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_43570 conjugal transfer protein TrbE\tK20530 trbE; type IV secretion system protein TrbE [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_15640 conjugal transfer protein TrbF\tK20531 trbF; type IV secretion system protein TrbF"
			},
			{
				"name":"Rmf_43600 conjugal transfer protein TrbF\tK20531 trbF; type IV secretion system protein TrbF"
			},
			{
				"name":"Rmf_15650 trbG_1; P-type conjugative transfer protein TrbG\tK20532 trbG; type IV secretion system protein TrbG"
			},
			{
				"name":"Rmf_43610 trbG_2; P-type conjugative transfer protein TrbG\tK20532 trbG; type IV secretion system protein TrbG"
			},
			{
				"name":"Rmf_15660 conjugal transfer protein TraI\tK20533 trbI; type IV secretion system protein TrbI"
			},
			{
				"name":"Rmf_43620 conjugal transfer protein TraI\tK20533 trbI; type IV secretion system protein TrbI"
			},
			{
				"name":"Rmf_15620 conjugal transfer protein TrbJ\tK20266 trbJ; type IV secretion system protein TrbJ"
			},
			{
				"name":"Rmf_43580 conjugal transfer protein TrbJ\tK20266 trbJ; type IV secretion system protein TrbJ"
			},
			{
				"name":"Rmf_15630 trbL1_1; conjugal transfer protein TrbL\tK07344 trbL; type IV secretion system protein TrbL"
			},
			{
				"name":"Rmf_43590 trbL1_2; conjugal transfer protein TrbL\tK07344 trbL; type IV secretion system protein TrbL"
			}
			]
		}
		]
	},
	{
		"name":"Type V secretion system",
		"children":[
		{
			"name":"Autotransporter-1 (AT-1) family"
		},
		{
			"name":"Autotransporter-2 (AT-2) family"
		},
		{
			"name":"Two-partner secretion (TPS) family"
		}
		]
	},
	{
		"name":"Type VI secretion system",
		"children":[
		{
			"name":"Imp\/Vas secretion system core components",
			"children":[
			{
				"name":"Rmf_33340 icmF1; type VI secretion protein IcmF\tK11891 impL; type VI secretion system protein ImpL"
			},
			{
				"name":"Rmf_33350 impK; cell envelope biogenesis protein OmpA\tK11892 impK; type VI secretion system protein ImpK"
			},
			{
				"name":"Rmf_33360 impJ; type VI secretion protein\tK11893 impJ; type VI secretion system protein ImpJ"
			},
			{
				"name":"Rmf_33200 type VI secretion protein\tK11895 impH; type VI secretion system protein ImpH"
			},
			{
				"name":"Rmf_33210 impG; type VI secretion system protein ImpG\tK11896 impG; type VI secretion system protein ImpG"
			},
			{
				"name":"Rmf_33220 hypothetical protein\tK11897 impF; type VI secretion system protein ImpF"
			},
			{
				"name":"Rmf_03060 hypothetical protein\tK11900 impC; type VI secretion system protein ImpC"
			},
			{
				"name":"Rmf_33250 impC; type VI secretion protein EvpB\tK11900 impC; type VI secretion system protein ImpC"
			},
			{
				"name":"Rmf_33260 impB; type VI secretion protein\tK11901 impB; type VI secretion system protein ImpB"
			},
			{
				"name":"Rmf_33270 impA; type VI secretion protein\tK11902 impA; type VI secretion system protein ImpA"
			},
			{
				"name":"Rmf_33290 hypothetical protein\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"Rmf_33310 hypothetical protein\tK11903 hcp; type VI secretion system secreted protein Hcp"
			},
			{
				"name":"Rmf_13470 hypothetical protein\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"Rmf_22770 type IV secretion protein Rhs\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"Rmf_41450 hypothetical protein\tK11904 vgrG; type VI secretion system secreted protein VgrG"
			},
			{
				"name":"Rmf_33280 clpB_2; protease associated ATPase ClpB\tK11907 vasG; type VI secretion system protein VasG"
			}
			]
		},
		{
			"name":"Imp\/Vas secretion system related proteins",
			"children":[
			{
				"name":"Rmf_33330 hypothetical protein\tK11890 impM; type VI secretion system protein ImpM"
			},
			{
				"name":"Rmf_33230 protein of avirulence locus\tK11898 impE; type VI secretion system protein ImpE"
			},
			{
				"name":"Rmf_33240 hypothetical protein\tK11899 impD; type VI secretion system protein ImpD"
			},
			{
				"name":"Rmf_23010 serine\/threonine protein kinase\tK11912 ppkA; serine\/threonine-protein kinase PpkA [EC:2.7.11.1]"
			},
			{
				"name":"Rmf_33370 hypothetical protein\tK11913 fha1; type VI secretion system protein"
			}
			]
		}
		]
	},
	{
		"name":"Type VII secretion system",
		"children":[
		{
			"name":"ESX secretion system protein"
		}
		]
	},
	{
		"name":"Chaperone-usher system",
		"children":[
		{
			"name":"Type 1 pilus assembly protein"
		},
		{
			"name":"P pilus assembly protein"
		},
		{
			"name":"Mat\/Ecp fimbriae assembly protein"
		}
		]
	},
	{
		"name":"Extracellular nucleation-precipitation pathway",
		"children":[
		{
			"name":"Curli assembly protein"
		}
		]
	},
	{
		"name":"Sec (secretion) system",
		"children":[
		{
			"name":"Prokaryotic Sec-SRP core components",
			"children":[
			{
				"name":"Rmf_07910 secA; protein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
			},
			{
				"name":"Rmf_03270 secB; protein-export protein SecB\tK03071 secB; preprotein translocase subunit SecB"
			},
			{
				"name":"Rmf_25850 protein translocase subunit SecDF\tK12257 secDF; SecD\/SecF fusion protein"
			},
			{
				"name":"Rmf_41310 secE; protein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
			},
			{
				"name":"Rmf_32330 hypothetical protein\tK03075 secG; preprotein translocase subunit SecG"
			},
			{
				"name":"Rmf_40950 secY; protein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
			},
			{
				"name":"Rmf_33540 ffh; signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			},
			{
				"name":"Rmf_09320 hypothetical protein\tK03110 ftsY; fused signal recognition particle receptor"
			},
			{
				"name":"Rmf_26400 hypothetical protein\tK03210 yajC; preprotein translocase subunit YajC"
			},
			{
				"name":"Rmf_10030 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
			}
			]
		},
		{
			"name":"Prokaryotic Sec-SRP related proteins"
		},
		{
			"name":"Eukaryotic Sec-SRP protein",
			"children":[
			{
				"name":"Rmf_33540 ffh; signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
			}
			]
		}
		]
	},
	{
		"name":"Twin-arginine translocation (Tat) system",
		"children":[
		{
			"name":"Twin-arginine translocation (Tat) pathway protein",
			"children":[
			{
				"name":"Rmf_06940 hypothetical protein\tK03116 tatA; sec-independent protein translocase protein TatA"
			},
			{
				"name":"Rmf_26460 hypothetical protein\tK03117 tatB; sec-independent protein translocase protein TatB"
			},
			{
				"name":"Rmf_26450 tatC; Sec-independent protein translocase protein TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
			}
			]
		}
		]
	}
	]
}
