{
	"name":"rphi00536",
	"children":[
	{
		"name":"Heparan sulfate \/ Heparin",
		"children":[
		{
			"name":"Cytokines",
			"children":[
			{
				"name":"132747585 uncharacterized protein LOC132747585\tK03156 TNF; tumor necrosis factor superfamily, member 2"
			},
			{
				"name":"132749616 uncharacterized protein LOC132749616\tK03156 TNF; tumor necrosis factor superfamily, member 2"
			},
			{
				"name":"132754719 uncharacterized protein LOC132754719 isoform X1\tK03156 TNF; tumor necrosis factor superfamily, member 2"
			}
			]
		},
		{
			"name":"Chemokines",
			"children":[
			{
				"name":"------  CCL12; C-C motif chemokine 12 [MMU:20293] [KO:K14624]"
			}
			]
		},
		{
			"name":"Adhesion molecules of cell surface",
			"children":[
			{
				"name":"132758669 sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1-like\tK06496 SELP; selectin, platelet"
			},
			{
				"name":"132722908 hemicentin-1-like\tK06491 NCAM; neural cell adhesion molecule"
			},
			{
				"name":"132737057 neural cell adhesion molecule 1-like\tK06491 NCAM; neural cell adhesion molecule"
			}
			]
		},
		{
			"name":"Morphogens",
			"children":[
			{
				"name":"132715091 bone morphogenetic protein 2-like isoform X1\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"132723754 bone morphogenetic protein 4-like\tK21283 BMP2; bone morphogenetic protein 2"
			},
			{
				"name":"132742330 bone morphogenetic protein 7-like\tK16621 BMP7; bone morphogenetic protein 7"
			},
			{
				"name":"132739801 sonic hedgehog protein-like\tK11988 SHH; sonic hedgehog"
			},
			{
				"name":"132743289 protein Wnt-1-like\tK03209 WNT1; wingless-type MMTV integration site family, member 1"
			},
			{
				"name":"132747988 protein Wnt-2b-A-like isoform X1\tK00182 WNT2; wingless-type MMTV integration site family, member 2"
			},
			{
				"name":"132716283 protein Wnt-4-like\tK00408 WNT4; wingless-type MMTV integration site family, member 4"
			},
			{
				"name":"132734930 protein Wnt-4-like\tK00408 WNT4; wingless-type MMTV integration site family, member 4"
			},
			{
				"name":"132748104 protein Wnt-5a-like\tK00444 WNT5; wingless-type MMTV integration site family, member 5"
			},
			{
				"name":"132743290 protein Wnt-6-like isoform X1\tK00445 WNT6; wingless-type MMTV integration site family, member 6"
			},
			{
				"name":"132755699 protein Wnt-7b-like isoform X1\tK00572 WNT7; wingless-type MMTV integration site family, member 7"
			},
			{
				"name":"132749482 protein Wnt-10a-like\tK00714 WNT8; wingless-type MMTV integration site family, member 8"
			},
			{
				"name":"132743286 protein Wnt-9a-like\tK01064 WNT9; wingless-type MMTV integration site family, member 9"
			},
			{
				"name":"132743277 protein Wnt-10b-like\tK01357 WNT10; wingless-type MMTV integration site family, member 10"
			},
			{
				"name":"132717642 protein Wnt-11b-2-like\tK01384 WNT11; wingless-type MMTV integration site family, member 11"
			},
			{
				"name":"132738410 protein Wnt-16-like isoform X1\tK01558 WNT16; wingless-type MMTV integration site family, member 16"
			}
			]
		},
		{
			"name":"Growth factors\/receptors",
			"children":[
			{
				"name":"132755479 fibroblast growth factor 18-like isoform X1\tK04358 FGF; fibroblast growth factor"
			}
			]
		},
		{
			"name":"Extracellular matrix molecules",
			"children":[
			{
				"name":"132716014 fibrillin-2-like isoform X1\tK06825 FBN1; fibrillin 1"
			},
			{
				"name":"132724931 LOW QUALITY PROTEIN: fibrillin-2-like\tK23342 FBN2_3; fibrillin 2\/3"
			},
			{
				"name":"------  LAMA5; laminin, alpha 5 [HSA:3911] [KO:K06240]"
			},
			{
				"name":"132722762 SPARC-related modular calcium-binding protein 1-like isoform X1\tK24354 SMOC; SPARC-related modular calcium-binding protein"
			},
			{
				"name":"132716560 cartilage oligomeric matrix protein-like\tK04659 THBS2S; thrombospondin 2\/3\/4\/5"
			},
			{
				"name":"132732176 cartilage oligomeric matrix protein-like\tK04659 THBS2S; thrombospondin 2\/3\/4\/5"
			},
			{
				"name":"132735573 collagen alpha-1(I) chain-like\tK06236 COL1A; collagen type I alpha"
			},
			{
				"name":"132735579 collagen alpha-1(I) chain-like\tK06236 COL1A; collagen type I alpha"
			},
			{
				"name":"132717260 collagen alpha-2(IV) chain-like\tK06237 COL4A; collagen type IV alpha"
			},
			{
				"name":"132754164 collagen alpha-1(IV) chain-like\tK06237 COL4A; collagen type IV alpha"
			},
			{
				"name":"132733346 collagen alpha-1(I) chain-like\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			},
			{
				"name":"132752336 collagen alpha-3(IX) chain-like isoform X1\tK19721 COL5AS; collagen type V\/XI\/XXIV\/XXVII, alpha"
			}
			]
		},
		{
			"name":"Axon guidance molecules",
			"children":[
			{
				"name":"132715217 netrin-1-like isoform X1\tK06843 NTN1; netrin 1"
			},
			{
				"name":"132740822 protein slit-like isoform X1\tK06839 SLIT2; slit 2"
			},
			{
				"name":"------  SEMA5A; semaphorin 5A [HSA:9037] [KO:K06841]"
			}
			]
		},
		{
			"name":"Coagulation and fibrinolysis",
			"children":[
			{
				"name":"132730096 coagulation factor IX-like\tK01313 F2; coagulation factor II (thrombin) [EC:3.4.21.5]"
			},
			{
				"name":"132726139 carboxypeptidase inhibitor SmCI-like\tK03909 TFPI; tissue factor pathway inhibitor"
			},
			{
				"name":"132750962 carboxypeptidase inhibitor SmCI-like\tK03909 TFPI; tissue factor pathway inhibitor"
			},
			{
				"name":"132751743 carboxypeptidase inhibitor SmCI-like\tK03909 TFPI; tissue factor pathway inhibitor"
			}
			]
		},
		{
			"name":"Enzymes",
			"children":[
			{
				"name":"132728837 heparanase-like\tK07964 HPSE; heparanase [EC:3.2.1.166]"
			},
			{
				"name":"132745911 heparanase-like\tK07964 HPSE; heparanase [EC:3.2.1.166]"
			},
			{
				"name":"132749711 hyaluronidase-like\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
			},
			{
				"name":"132735014 uncharacterized protein LOC132735014\tK16627 SOD3; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]"
			}
			]
		},
		{
			"name":"Microbial pathogens",
			"children":[
			{
				"name":"------  Dengue virus, envelope protein"
			},
			{
				"name":"------  Foot-and-mouth disease virus - type O, VP3"
			},
			{
				"name":"------  penetrin"
			},
			{
				"name":"------  Borrelia burgdorferi"
			},
			{
				"name":"------  Chlamydia trachomatis"
			},
			{
				"name":"------  Neisseria gonorrhoeae"
			},
			{
				"name":"------  Leishmania amazonensis"
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"132729818 cathepsin B-like\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"132713057 sodium\/calcium exchanger 3-like isoform X1\tK05849 SLC8A; solute carrier family 8 (sodium\/calcium exchanger)"
			},
			{
				"name":"132721949 sodium\/calcium exchanger 2-like\tK05849 SLC8A; solute carrier family 8 (sodium\/calcium exchanger)"
			},
			{
				"name":"132743643 sodium\/calcium exchanger 1-like\tK05849 SLC8A; solute carrier family 8 (sodium\/calcium exchanger)"
			}
			]
		}
		]
	},
	{
		"name":"Hyaluronan",
		"children":[
		{
			"name":"Cell surface receptors",
			"children":[
			{
				"name":"132750226 hyaluronan mediated motility receptor-like isoform X1\tK06267 HMMR; hyaluronan-mediated motility receptor"
			},
			{
				"name":"132720377 protein toll-like\tK10159 TLR2; toll-like receptor 2"
			},
			{
				"name":"132744805 toll-like receptor 4\tK10159 TLR2; toll-like receptor 2"
			},
			{
				"name":"132733837 protein toll-like\tK10160 TLR4; toll-like receptor 4"
			},
			{
				"name":"132738576 toll-like receptor 4\tK10160 TLR4; toll-like receptor 4"
			},
			{
				"name":"132739446 CD180 antigen-like\tK10160 TLR4; toll-like receptor 4"
			},
			{
				"name":"132716196 cell migration-inducing and hyaluronan-binding protein-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132716198 protein DDB_G0287365-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132726534 cell migration-inducing and hyaluronan-binding protein-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132731368 protein DDB_G0287365-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132748963 cell migration-inducing and hyaluronan-binding protein-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132750591 cell surface hyaluronidase-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132751844 cell migration-inducing and hyaluronan-binding protein-like\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			},
			{
				"name":"132755476 protein DDB_G0287365-like isoform X1\tK22144 TEME2; cell surface hyaluronidase [EC:3.2.1.35]"
			}
			]
		},
		{
			"name":"Extracellular matrix or blood plasma proteins",
			"children":[
			{
				"name":"132728060 complement component 1 Q subcomponent-binding protein, mitochondrial-like\tK15414 C1QBP; complement component 1 Q subcomponent-binding protein, mitochondrial"
			},
			{
				"name":"132725361 inter-alpha-trypsin inhibitor heavy chain H3-like\tK19014 ITIH1; inter-alpha-trypsin inhibitor heavy chain H1"
			},
			{
				"name":"132714284 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			},
			{
				"name":"132720028 inter-alpha-trypsin inhibitor heavy chain H3-like isoform X1\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			},
			{
				"name":"132725365 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			},
			{
				"name":"132725370 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			},
			{
				"name":"132756827 inter-alpha-trypsin inhibitor heavy chain H3-like\tK24513 ITIH3; inter-alpha-trypsin inhibitor heavy chain H3"
			}
			]
		},
		{
			"name":"Intracellular proteins",
			"children":[
			{
				"name":"132748454 hsp90 co-chaperone Cdc37-like\tK09554 CDC37; cell division cycle protein 37"
			}
			]
		}
		]
	}
	]
}