{
	"name":"rsz03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"108828233 origin of replication complex subunit 1B\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"108807256 origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"108814806 origin of replication complex subunit 3\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"108835668 origin of replication complex subunit 4\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"108833677 origin of replication complex subunit 5\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"108808304 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"108821205 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"108811480 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"108836687 CDT1-like protein b\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"108838686 CDT1-like protein b\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"108845880 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"108805586 cell division control protein 6 homolog\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"108862824 LOW QUALITY PROTEIN: cell division control protein 6 homolog B-like\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"108862831 LOW QUALITY PROTEIN: cell division control protein 6 homolog B\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"130503841 cell division control protein 6 homolog\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"108811792 DNA replication licensing factor MCM2\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"108820289 LOW QUALITY PROTEIN: DNA replication licensing factor MCM2-like\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"108806763 DNA replication licensing factor MCM3\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"108833607 DNA replication licensing factor MCM3\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"108805243 DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"108862143 DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"108856150 DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"108855922 LOW QUALITY PROTEIN: DNA replication licensing factor MCM6\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"108837502 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				},
				{
					"name":"108847257 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"108815896 cyclin-A2-4-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108817577 cyclin-A2-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108819232 cyclin-A3-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108819278 cyclin-A1-1 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108822667 cyclin-A3-4 isoform X2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108822710 cyclin-A2-3-like isoform X4\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108823447 cyclin-A2-4-like isoform X3\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108826284 cyclin-A1-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108826756 cyclin-A3-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108828176 cyclin-A2-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108835195 cyclin-A1-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108842543 cyclin-A2-4\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108846049 cyclin-A2-4\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108855476 cyclin-A3-4 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108857473 cyclin-A3-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108857721 cyclin-A1-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108858065 cyclin-A1-2-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108861965 cyclin-A2-3\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"130504052 LOW QUALITY PROTEIN: cyclin-A2-1-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"108806178 cyclin-dependent kinase A-1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"108856600 cyclin-dependent kinase A-1 isoform X1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"108824289 uncharacterized protein LOC108824289 isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"108814298 uncharacterized protein LOC108814298 isoform X2\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"108816222 uncharacterized protein LOC108816222 isoform X1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"108809543 DNA replication complex GINS protein PSF2\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"108863572 LOW QUALITY PROTEIN: DNA replication complex GINS protein PSF2-like\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"130496695 DNA replication complex GINS protein PSF2-like\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"108820859 DNA replication complex GINS protein PSF3-like\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"108851354 DNA replication complex GINS protein PSF3\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"108837180 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"108828183 uncharacterized protein LOC108828183\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"108844048 BRCT domain-containing protein At4g02110 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"108857092 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"108805363 uncharacterized protein LOC108805363\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"108863433 uncharacterized protein LOC108863433\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"130505393 uncharacterized protein LOC130505393\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"108862970 probable DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"108857774 probable DNA helicase MCM9\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"108844110 LOW QUALITY PROTEIN: uncharacterized protein LOC108844110\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"108845076 uncharacterized protein LOC108845076 isoform X1\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"108852013 mini-chromosome maintenance complex-binding protein\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"108812415 DNA polymerase alpha catalytic subunit isoform X1\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"108817867 uncharacterized protein LOC108817867\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"108815977 LOW QUALITY PROTEIN: uncharacterized protein LOC108815977\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"108851456 uncharacterized protein LOC108851456\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"108839767 probable DNA primase large subunit isoform X1\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"108862749 DNA polymerase epsilon catalytic subunit A isoform X1\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"108810115 DNA polymerase epsilon subunit B-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"108810133 DNA polymerase epsilon subunit B-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"108830184 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"130501441 DNA polymerase epsilon subunit B-like\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"108812955 DNA polymerase II subunit B4\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"108862973 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"108851667 DNA polymerase delta small subunit isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"108823689 uncharacterized protein LOC108823689\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"108827019 uncharacterized protein LOC108827019\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"108810727 uncharacterized protein LOC108810727\tK03505 POLD4; DNA polymerase delta subunit 4"
				},
				{
					"name":"130508643 uncharacterized protein LOC130508643\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"108806871 replication protein A 70 kDa DNA-binding subunit C isoform X1\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"108823574 replication protein A 70 kDa DNA-binding subunit D\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"108844495 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"108855522 replication protein A 70 kDa DNA-binding subunit E\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"108857288 replication protein A 70 kDa DNA-binding subunit D\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"130502272 replication protein A 70 kDa DNA-binding subunit D\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"130505170 replication protein A 70 kDa DNA-binding subunit E-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"130510874 replication protein A 70 kDa DNA-binding subunit D\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"108807368 replication protein A 32 kDa subunit B\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"108849168 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"108823214 replication protein A 14 kDa subunit B\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"108842389 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"108845569 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"130509455 replication factor C subunit 1-like\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"108822640 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108823962 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108859282 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"130499537 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"130506297 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108809068 replication factor C subunit 3 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108814696 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108835753 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108839949 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108855487 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"108851725 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"108839689 uncharacterized protein LOC108839689\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"108851836 uncharacterized protein LOC108851836 isoform X1\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"108807162 uncharacterized protein LOC108807162 isoform X1\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"108808570 proliferating cellular nuclear antigen 1\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"108813636 proliferating cell nuclear antigen 2\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"108832540 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"130509688 proliferating cellular nuclear antigen 1-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"108863606 DNA replication ATP-dependent helicase\/nuclease JHS1 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"108848985 flap endonuclease 1 isoform X2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"108821748 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"108856446 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"130505591 exonuclease 1-like\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"130506433 exonuclease 1-like\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"108847484 LOW QUALITY PROTEIN: uncharacterized protein LOC108847484\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"108806676 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"130502081 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"108840548 uncharacterized protein LOC108840548\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"108807343 putative DNA (cytosine-5)-methyltransferase CMT1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108812222 DNA (cytosine-5)-methyltransferase 1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108829897 DNA (cytosine-5)-methyltransferase 1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108843473 DNA (cytosine-5)-methyltransferase CMT2 isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108850263 DNA (cytosine-5)-methyltransferase 1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108853226 DNA (cytosine-5)-methyltransferase 1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108860301 DNA (cytosine-5)-methyltransferase CMT3\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"130510109 putative DNA (cytosine-5)-methyltransferase CMT1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"108827717 PWWP domain-containing protein 1\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"108827718 PWWP domain-containing protein 1\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"108805349 cyclin-B2-1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108805966 putative cyclin-B3-1 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108809283 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108809577 cyclin-B1-3\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108814466 cyclin-B2-4\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108818910 cyclin-B2-3\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108819409 cyclin-B1-2\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108820757 putative cyclin-B3-1 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108820993 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108821413 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108826152 cyclin-B2-1-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108833186 cyclin-B1-3\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108833599 cyclin-B2-4\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108833617 cyclin-B1-2\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108841097 cyclin-B1-1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108842004 cyclin-SDS\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108851387 cyclin-B2-2\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"108863124 cyclin-B2-3 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex"
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"108819141 CST complex subunit STN1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"108809136 CST complex subunit TEN1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"108806903 telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"108814858 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"108840481 telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"108807299 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"108834255 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"108844694 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"130501041 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"130501737 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"108818409 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"108826973 LOW QUALITY PROTEIN: H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"108846444 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"108812622 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"108812657 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"108825842 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"108818330 H\/ACA ribonucleoprotein complex subunit 4\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"108830489 H\/ACA ribonucleoprotein complex subunit 4\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"108806903 telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"108814858 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"108840481 telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"108818305 uncharacterized protein LOC108818305\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"108819102 uncharacterized protein LOC108819102\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"108855840 uncharacterized protein LOC108855840\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"130511975 uncharacterized protein LOC130511975\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"108809034 small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"108847028 small nuclear ribonucleoprotein SmD1b\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"108857594 small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"130497084 small nuclear ribonucleoprotein SmD1a-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"108817121 uncharacterized protein LOC108817121 isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"108855653 uncharacterized protein LOC108855653 isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"108861208 uncharacterized protein LOC108861208 isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"130502204 uncharacterized protein LOC130502204 isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"108814661 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"108818911 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"108863147 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"108809337 uncharacterized protein LOC108809337 isoform X2\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"108862220 uncharacterized protein LOC108862220\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"108820749 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"108837975 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"108852389 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"108809241 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"108836646 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"108859285 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"108822640 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108823962 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108859282 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"130499537 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"130506297 replication factor C subunit 4-like\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"108809068 replication factor C subunit 3 isoform X2\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108814696 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108835753 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108839949 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"108855487 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"108848716 double-strand break repair protein MRE11 isoform X3\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"108847928 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"130507326 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"130507455 DNA repair protein RAD50-like\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"108836280 nibrin homolog\tK10867 NBN; nibrin"
				},
				{
					"name":"108852970 nibrin homolog\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"108829153 serine\/threonine-protein kinase ATM isoform X4\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"108855607 ATP-dependent DNA helicase Q-like SIM isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"108808655 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108821900 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108821908 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108823929 ATP-dependent DNA helicase Q-like 4B\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108837794 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108862164 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"130504086 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"108854209 DNA repair endonuclease UVH1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"108813665 poly [ADP-ribose] polymerase 1 isoform X1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"108820008 LOW QUALITY PROTEIN: poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"108847586 poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"130494515 poly [ADP-ribose] polymerase 2-like isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"108825476 G-patch domain-containing protein 1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"108825876 G-patch domain-containing protein 1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"130499725 G-patch domain-containing protein 1-like\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"108818486 regulator of telomere elongation helicase 1 homolog isoform X1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"108829155 uncharacterized protein LOC108829155\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"108812003 transcription factor Pur-alpha 1\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"108839809 uncharacterized protein LOC108839809\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"108828540 uncharacterized protein LOC108828540\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"108828707 uncharacterized protein LOC108828707\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"108828296 DNA topoisomerase 1 beta\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"108837915 DNA topoisomerase 1 beta-like\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"108841046 DNA topoisomerase 1 alpha\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"108842640 DNA topoisomerase 1 alpha\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"108842497 DNA topoisomerase 2\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"108807153 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"108847982 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"108848032 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"108809240 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"108859562 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"130505474 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"130505922 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"130512872 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"108862371 DNA polymerase I B, chloroplastic\/mitochondrial\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"108863023 DNA polymerase I A, chloroplastic\/mitochondrial\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"108863606 DNA replication ATP-dependent helicase\/nuclease JHS1 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"108848985 flap endonuclease 1 isoform X2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"108806676 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"130502081 DNA ligase 1-like\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"108838570 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"108862053 DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"108805387 DNA gyrase subunit B, chloroplastic isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"108817756 AT-rich interactive domain-containing protein 1 isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"108843313 DNA gyrase subunit B, mitochondrial isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"108847526 DNA gyrase subunit B, mitochondrial\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"108847527 uncharacterized protein LOC108847527\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"108861326 DNA topoisomerase 6 subunit B isoform X1\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}