{
	"name":"saim03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others",
				"children":[
				{
					"name":"K0C01_07175 single-stranded DNA binding protein\tK07466 RFA1; replication factor A1"
				}
				]
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins",
				"children":[
				{
					"name":"K0C01_03815 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
				},
				{
					"name":"K0C01_10520 TATA-box-binding protein\tK03120 TBP; transcription initiation factor TFIID TATA-box-binding protein"
				}
				]
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family"
			},
			{
				"name":"DeoR family"
			},
			{
				"name":"LacI family"
			},
			{
				"name":"GntR family"
			},
			{
				"name":"TetR\/AcrR family"
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"K0C01_09125 Lrp\/AsnC family transcriptional regulator\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family"
			},
			{
				"name":"MerR family"
			},
			{
				"name":"Fur family"
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"K0C01_05485 IclR family transcriptional regulator\tK21827 arcR; IclR family transcriptional regulator, arginine deiminase pathway regulator"
				}
				]
			},
			{
				"name":"CRP\/FNR family"
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"K0C01_06420 helix-turn-helix domain-containing protein\tK29059 csmR; ArsR family transcriptional regulator, cell shape and motility regulator"
				},
				{
					"name":"K0C01_07270 ArsR family transcriptional regulator\tK07721 K07721; ArsR family transcriptional regulator"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"K0C01_00640 transcriptional regulator\tK22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator"
				},
				{
					"name":"K0C01_03175 helix-turn-helix domain-containing protein\tK22206 thiR; XRE family transcriptional regulator, thiamine biosynthesis regulator"
				}
				]
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"K0C01_03385 metal-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"K0C01_07035 metal-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"K0C01_08835 metal-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"K0C01_08125 biotin--[acetyl-CoA-carboxylase] ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"K0C01_10045 TrmB family transcriptional regulator\tK23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator"
				},
				{
					"name":"K0C01_10390 TrmB family transcriptional regulator\tK23356 trmB; HTH-type transcriptional regulator, sugar sensing transcriptional regulator"
				},
				{
					"name":"K0C01_00520 helix-turn-helix domain-containing protein\tK06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins"
				},
				{
					"name":"K0C01_01980 helix-turn-helix domain-containing protein\tK06930 bat; HTH-type transcriptional regulator, bacterioopsin transcriptional activator and related proteins"
				},
				{
					"name":"K0C01_00035 helix-turn-helix domain-containing protein\tK23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator"
				},
				{
					"name":"K0C01_10475 helix-turn-helix domain-containing protein\tK23348 dmsR; HTH-type transcriptional regulator, dimethyl sulfoxide reductase transcription regulator"
				},
				{
					"name":"K0C01_05765 Tfx family DNA-binding protein\tK09714 tfx; HTH-type transcriptional regulator, fmd operon transcriptional regulator"
				},
				{
					"name":"K0C01_02150 orotate phosphoribosyltransferase-like protein\tK26599 gfcR; HTH-type transcriptional regulator, activator of D-glucose\/D-fructose catabolism"
				},
				{
					"name":"K0C01_11630 TOBE domain-containing protein\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"K0C01_04780 transcriptional regulator\tK07728 K07728; putative transcriptional regulator"
				},
				{
					"name":"K0C01_06995 winged helix-turn-helix transcriptional regulator\tK07730 K07730; putative transcriptional regulator"
				},
				{
					"name":"K0C01_01590 helix-turn-helix domain-containing protein\tK07731 K07731; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"K0C01_03760 CopG family ribbon-helix-helix protein\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				},
				{
					"name":"K0C01_04115 nikR; nickel-responsive transcriptional regulator NikR\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				},
				{
					"name":"K0C01_11915 ribbon-helix-helix protein, CopG family\tK07722 nikR; CopG family transcriptional regulator, nickel-responsive regulator"
				}
				]
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}