{
	"name":"scc00001",
	"children":[
	{
		"name":"09100 Metabolism",
		"children":[
		{
			"name":"09101 Carbohydrate metabolism",
			"children":[
			{
				"name":"00010 Glycolysis \/ Gluconeogenesis [PATH:scc00010]",
				"children":[
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1786 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0010 glucose-6-phosphate isomerase\tK06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_0889 pyrophosphate-dependent phosphofructokinase\tK00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0925 fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0473 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Spico_0471 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Spico_0086 glyceraldehyde-3-phosphate dehydrogenase\tK00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]"
				},
				{
					"name":"Spico_0087 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0472 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0424 phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Spico_0349 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Spico_0628 pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]"
				},
				{
					"name":"Spico_1653 Dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1805 pyruvate ferredoxin\/flavodoxin oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]"
				},
				{
					"name":"Spico_1643 L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_0968 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Spico_0176 HAD-superfamily hydrolase, subfamily IA, variant 3\tK20866 yihX; glucose-1-phosphatase [EC:3.1.3.10]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_1316 Phosphoenolpyruvate carboxykinase (GTP)\tK01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]"
				}
				]
			},
			{
				"name":"00020 Citrate cycle (TCA cycle) [PATH:scc00020]",
				"children":[
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1443 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, alpha subunit\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1442 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, beta subunit\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1310 Pyruvate carboxylase\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]"
				},
				{
					"name":"Spico_1316 Phosphoenolpyruvate carboxykinase (GTP)\tK01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]"
				},
				{
					"name":"Spico_1653 Dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Spico_1805 pyruvate ferredoxin\/flavodoxin oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]"
				}
				]
			},
			{
				"name":"00030 Pentose phosphate pathway [PATH:scc00030]",
				"children":[
				{
					"name":"Spico_1786 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0010 glucose-6-phosphate isomerase\tK06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0606 ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Spico_0121 transketolase subunit A\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Spico_0122 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Spico_1077 ribose-5-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Spico_0036 Deoxyribose-phosphate aldolase\tK01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]"
				},
				{
					"name":"Spico_0021 ribokinase\tK00852 rbsK; ribokinase [EC:2.7.1.15]"
				},
				{
					"name":"Spico_1255 Ribokinase\tK00852 rbsK; ribokinase [EC:2.7.1.15]"
				},
				{
					"name":"Spico_1510 metalloenzyme domain protein\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_1046 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"Spico_0041 2-dehydro-3-deoxyphosphogluconate aldolase\/4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"Spico_0042 PfkB domain protein\tK00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]"
				},
				{
					"name":"Spico_1227 Aldehyde ferredoxin oxidoreductase\tK03738 aor; aldehyde:ferredoxin oxidoreductase [EC:1.2.7.5]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0925 fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_0889 pyrophosphate-dependent phosphofructokinase\tK00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]"
				}
				]
			},
			{
				"name":"00040 Pentose and glucuronate interconversions [PATH:scc00040]",
				"children":[
				{
					"name":"Spico_0157 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				},
				{
					"name":"Spico_1844 4-deoxy-L-threo-5-hexulose uronate isomerase\tK01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17]"
				},
				{
					"name":"Spico_1205 Alpha-galactosidase\tK22933 lplD; galacturan 1,4-alpha-galacturonidase [EC:3.2.1.67]"
				},
				{
					"name":"Spico_0046 D-glucuronate isomerase\tK01812 uxaC; glucuronate isomerase [EC:5.3.1.12]"
				},
				{
					"name":"Spico_0048 tagaturonate reductase\tK00041 uxaB; tagaturonate reductase [EC:1.1.1.58]"
				},
				{
					"name":"Spico_0047 D-altronate dehydratase\tK01685 uxaA; altronate hydrolase [EC:4.2.1.7]"
				},
				{
					"name":"Spico_1185 D-mannonate dehydratase\tK01686 uxuA; mannonate dehydratase [EC:4.2.1.8]"
				},
				{
					"name":"Spico_1183 Mannitol 2-dehydrogenase\tK00040 uxuB; fructuronate reductase [EC:1.1.1.57]"
				},
				{
					"name":"Spico_0343 L-ribulose 5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				},
				{
					"name":"Spico_0606 ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Spico_0342 L-arabinose isomerase\tK01804 araA; L-arabinose isomerase [EC:5.3.1.4]"
				},
				{
					"name":"Spico_0017 Xylulokinase\tK00854 xylB; xylulokinase [EC:2.7.1.17]"
				},
				{
					"name":"Spico_0155 xylulokinase\tK00854 xylB; xylulokinase [EC:2.7.1.17]"
				},
				{
					"name":"Spico_0156 D-xylose isomerase\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Spico_1261 Xylose isomerase domain-containing protein TIM barrel\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Spico_1647 Rhamnulokinase\tK00848 rhaB; rhamnulokinase [EC:2.7.1.5]"
				},
				{
					"name":"Spico_1665 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				},
				{
					"name":"Spico_0120 class II aldolase\/adducin family protein\tK01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]"
				}
				]
			},
			{
				"name":"00051 Fructose and mannose metabolism [PATH:scc00051]",
				"children":[
				{
					"name":"Spico_0946 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"Spico_0280 mannose-6-phosphate isomerase, class I\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]"
				},
				{
					"name":"Spico_0956 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"Spico_1665 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				},
				{
					"name":"Spico_0120 class II aldolase\/adducin family protein\tK01628 fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]"
				},
				{
					"name":"Spico_1664 RbsD or FucU transport\tK02431 fucU; L-fucose mutarotase [EC:5.1.3.29]"
				},
				{
					"name":"Spico_1661 L-rhamnose isomerase\tK01813 rhaA; L-rhamnose isomerase [EC:5.3.1.14]"
				},
				{
					"name":"Spico_1647 Rhamnulokinase\tK00848 rhaB; rhamnulokinase [EC:2.7.1.5]"
				},
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_0889 pyrophosphate-dependent phosphofructokinase\tK00895 pfp; diphosphate-dependent phosphofructokinase [EC:2.7.1.90]"
				},
				{
					"name":"Spico_1649 3-oxoacyl-(acyl-carrier-protein) reductase\tK00068 srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140]"
				},
				{
					"name":"Spico_1648 Alcohol dehydrogenase zinc-binding domain protein\tK19956 sorE; L-sorbose 1-phosphate reductase [EC:1.1.1.-]"
				},
				{
					"name":"Spico_0156 D-xylose isomerase\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Spico_1261 Xylose isomerase domain-containing protein TIM barrel\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0925 fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0473 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Spico_1077 ribose-5-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				}
				]
			},
			{
				"name":"00052 Galactose metabolism [PATH:scc00052]",
				"children":[
				{
					"name":"Spico_0968 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Spico_0431 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_1232 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_0957 UDP-galactose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_0718 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_1613 glycoside hydrolase family 2 TIM barrel\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_0769 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Spico_1068 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Spico_0342 L-arabinose isomerase\tK01804 araA; L-arabinose isomerase [EC:5.3.1.4]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_1069 Glycoside hydrolase 97\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"Spico_0768 Oligo-1,6-glucosidase\tK01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]"
				}
				]
			},
			{
				"name":"00053 Ascorbate and aldarate metabolism [PATH:scc00053]",
				"children":[
				{
					"name":"Spico_0343 L-ribulose 5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00500 Starch and sucrose metabolism [PATH:scc00500]",
				"children":[
				{
					"name":"Spico_1069 Glycoside hydrolase 97\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"Spico_0720 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0747 broad-specificity cellobiase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0770 Beta-glucosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0936 Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				},
				{
					"name":"Spico_0935 Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Spico_0657 (1->4)-alpha-D-glucan branching enzyme\tK16149 K16149; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"Spico_0240 glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]"
				},
				{
					"name":"Spico_1050 Cyclomaltodextrinase\tK01208 cd; cyclomaltodextrinase \/ maltogenic alpha-amylase \/ neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]"
				},
				{
					"name":"Spico_0768 Oligo-1,6-glucosidase\tK01182 IMA; oligo-1,6-glucosidase [EC:3.2.1.10]"
				},
				{
					"name":"Spico_0443 4-alpha-glucanotransferase\tK00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]"
				},
				{
					"name":"Spico_1597 4-alpha-glucanotransferase\tK00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]"
				},
				{
					"name":"Spico_1537 beta-phosphoglucomutase\tK01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6]"
				},
				{
					"name":"Spico_1538 Kojibiose phosphorylase\tK05342 treP; alpha,alpha-trehalose phosphorylase [EC:2.4.1.64]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1786 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0010 glucose-6-phosphate isomerase\tK06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0946 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				}
				]
			},
			{
				"name":"00620 Pyruvate metabolism [PATH:scc00620]",
				"children":[
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_1805 pyruvate ferredoxin\/flavodoxin oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]"
				},
				{
					"name":"Spico_1653 Dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1550 formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"Spico_0875 acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"Spico_1011 phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"Spico_0349 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Spico_1566 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_1563 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Spico_1564 biotin carboxylase; acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Spico_1565 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_1643 L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"Spico_1581 Methylglyoxal reductase (NADPH-dependent)\tK23257 yvgN; methylglyoxal\/glyoxal reductase [EC:1.1.1.283 1.1.1.-]"
				},
				{
					"name":"Spico_0292 beta-lactamase domain protein\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]"
				},
				{
					"name":"Spico_0452 beta-lactamase domain protein\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]"
				},
				{
					"name":"Spico_0088 Protein of unknown function DUF2088\tK22373 larA; lactate racemase [EC:5.1.2.1]"
				},
				{
					"name":"Spico_1680 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]"
				},
				{
					"name":"Spico_0318 sodium ion-translocating decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1173 glutaconyl-CoA decarboxylase beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1310 Pyruvate carboxylase\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]"
				},
				{
					"name":"Spico_1443 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, alpha subunit\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1442 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, beta subunit\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1316 Phosphoenolpyruvate carboxykinase (GTP)\tK01596 E4.1.1.32; phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32]"
				},
				{
					"name":"Spico_0628 pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]"
				},
				{
					"name":"Spico_0322 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				},
				{
					"name":"Spico_0323 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:scc00630]",
				"children":[
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_0266 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Spico_1018 Phosphoglycolate phosphatase\tK01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]"
				},
				{
					"name":"Spico_1031 HAD-superfamily hydrolase, subfamily IA, variant 1\tK01091 gph; phosphoglycolate phosphatase [EC:3.1.3.18]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Spico_1215 glycine dehydrogenase (decarboxylating) alpha subunit\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1214 glycine dehydrogenase (decarboxylating) beta subunit\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1217 aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1216 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"Spico_1775 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Spico_0041 2-dehydro-3-deoxyphosphogluconate aldolase\/4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				}
				]
			},
			{
				"name":"00640 Propanoate metabolism [PATH:scc00640]",
				"children":[
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_0875 acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"Spico_1011 phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"Spico_1292 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1651 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1550 formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"Spico_1566 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_1563 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Spico_1564 biotin carboxylase; acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Spico_1565 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_1643 L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"Spico_1581 Methylglyoxal reductase (NADPH-dependent)\tK23257 yvgN; methylglyoxal\/glyoxal reductase [EC:1.1.1.283 1.1.1.-]"
				}
				]
			},
			{
				"name":"00650 Butanoate metabolism [PATH:scc00650]",
				"children":[
				{
					"name":"Spico_1558 reductase\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"Spico_0318 sodium ion-translocating decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1173 glutaconyl-CoA decarboxylase beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1550 formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"Spico_1805 pyruvate ferredoxin\/flavodoxin oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]"
				},
				{
					"name":"Spico_1615 Alcohol dehydrogenase (NADP(+))\tK23259 adh; isopropanol dehydrogenase (NADP+) [EC:1.1.1.80]"
				},
				{
					"name":"Spico_0328 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0320 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				}
				]
			},
			{
				"name":"00660 C5-Branched dibasic acid metabolism [PATH:scc00660]",
				"children":[
				{
					"name":"Spico_0328 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0320 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0324 3-isopropylmalate dehydratase, large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Spico_0325 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Spico_0326 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				}
				]
			},
			{
				"name":"00562 Inositol phosphate metabolism [PATH:scc00562]",
				"children":[
				{
					"name":"Spico_0082 myo-inositol 2-dehydrogenase\tK00010 iolG; myo-inositol 2-dehydrogenase \/ D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]"
				},
				{
					"name":"Spico_0085 2-keto-myo-inositol dehydratase\tK03335 iolE; inosose dehydratase [EC:4.2.1.44]"
				},
				{
					"name":"Spico_0084 3D-(3,5\/4)-trihydroxycyclohexane-1,2-dione hydrolase\tK03336 iolD; 3D-(3,5\/4)-trihydroxycyclohexane-1,2-dione acylhydrolase (decyclizing) [EC:3.7.1.22]"
				},
				{
					"name":"Spico_0083 myo-inositol catabolism IolB domain protein\tK03337 iolB; 5-deoxy-glucuronate isomerase [EC:5.3.1.30]"
				},
				{
					"name":"Spico_0473 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				}
				]
			},
			{
				"name":"00566 Sulfoquinovose metabolism"
			}
			]
		},
		{
			"name":"09102 Energy metabolism",
			"children":[
			{
				"name":"00190 Oxidative phosphorylation [PATH:scc00190]",
				"children":[
				{
					"name":"Spico_0757 V-type ATP synthase alpha chain\tK02117 ATPVA; V\/A-type H+\/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"Spico_0756 V-type ATP synthase beta chain\tK02118 ATPVB; V\/A-type H+\/Na+-transporting ATPase subunit B"
				},
				{
					"name":"Spico_0762 H+transporting two-sector ATPase C (AC39) subunit\tK02119 ATPVC; V\/A-type H+\/Na+-transporting ATPase subunit C"
				},
				{
					"name":"Spico_0755 V-type ATP synthase subunit D\tK02120 ATPVD; V\/A-type H+\/Na+-transporting ATPase subunit D"
				},
				{
					"name":"Spico_0758 H+transporting two-sector ATPase E subunit\tK02121 ATPVE; V\/A-type H+\/Na+-transporting ATPase subunit E"
				},
				{
					"name":"Spico_0759 Vacuolar H+transporting two-sector ATPase F subunit\tK02122 ATPVF; V\/A-type H+\/Na+-transporting ATPase subunit F"
				},
				{
					"name":"Spico_0761 V-type ATPase 116 kDa subunit\tK02123 ATPVI; V\/A-type H+\/Na+-transporting ATPase subunit I"
				},
				{
					"name":"Spico_0760 H+transporting two-sector ATPase C subunit\tK02124 ATPVK; V\/A-type H+\/Na+-transporting ATPase subunit K"
				}
				]
			},
			{
				"name":"00195 Photosynthesis"
			},
			{
				"name":"00196 Photosynthesis - antenna proteins"
			},
			{
				"name":"00710 Carbon fixation by Calvin cycle [PATH:scc00710]",
				"children":[
				{
					"name":"Spico_0087 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0472 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0471 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Spico_0086 glyceraldehyde-3-phosphate dehydrogenase\tK00150 gap2; glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) [EC:1.2.1.59]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0925 fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0121 transketolase subunit A\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Spico_0122 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Spico_1077 ribose-5-phosphate isomerase\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Spico_0473 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Spico_0606 ribulose-5-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Spico_0628 pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]"
				}
				]
			},
			{
				"name":"00720 Other carbon fixation pathways [PATH:scc00720]",
				"children":[
				{
					"name":"Spico_1805 pyruvate ferredoxin\/flavodoxin oxidoreductase\tK03737 por; pyruvate-ferredoxin\/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.8.1]"
				},
				{
					"name":"Spico_0628 pyruvate phosphate dikinase\tK01006 ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]"
				},
				{
					"name":"Spico_1310 Pyruvate carboxylase\tK01960 pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]"
				},
				{
					"name":"Spico_1443 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, alpha subunit\tK01677 E4.2.1.2AA; fumarate hydratase subunit alpha [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1442 hydro-lyase, Fe-S type, tartrate\/fumarate subfamily, beta subunit\tK01678 E4.2.1.2AB; fumarate hydratase subunit beta [EC:4.2.1.2]"
				},
				{
					"name":"Spico_1566 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_1563 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Spico_1564 biotin carboxylase; acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Spico_1565 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_0271 Formate-tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"Spico_0483 5; methenyltetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"Spico_0503 5,10-methylenetetrahydrofolate reductase\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"Spico_1011 phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"Spico_0875 acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				}
				]
			},
			{
				"name":"00680 Methane metabolism [PATH:scc00680]",
				"children":[
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0925 fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_0875 acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"Spico_1011 phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_0424 phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"Spico_0402 phosphoserine aminotransferase apoenzyme\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Spico_0290 phosphoserine phosphatase\/homoserine phosphotransferase bifunctional protein\tK02203 thrH; phosphoserine \/ homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]"
				},
				{
					"name":"Spico_1555 malate dehydrogenase (NAD)\tK05884 comC; L-2-hydroxycarboxylate dehydrogenase (NAD+) [EC:1.1.1.337]"
				}
				]
			},
			{
				"name":"00910 Nitrogen metabolism [PATH:scc00910]",
				"children":[
				{
					"name":"Spico_0375 glutamate dehydrogenase (NADP)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1768 glutamate dehydrogenase (NAD)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_0573 glutamate synthase (NADH) large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_0372 Glutamate synthase (NADPH)\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_0572 glutamate synthase (NADH) small subunit\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_1117 sulfide dehydrogenase (flavoprotein) subunit SudA\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				}
				]
			},
			{
				"name":"00920 Sulfur metabolism [PATH:scc00920]",
				"children":[
				{
					"name":"Spico_0677 inositol monophosphatase\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				},
				{
					"name":"Spico_0795 phosphoesterase RecJ domain protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				},
				{
					"name":"Spico_1008 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Spico_1758 cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"Spico_1472 homoserine O-succinyltransferase\tK00651 metA; homoserine O-succinyltransferase\/O-acetyltransferase [EC:2.3.1.46 2.3.1.31]"
				},
				{
					"name":"Spico_1380 Cystathionine gamma-lyase\tK01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]"
				}
				]
			}
			]
		},
		{
			"name":"09103 Lipid metabolism",
			"children":[
			{
				"name":"00061 Fatty acid biosynthesis [PATH:scc00061]",
				"children":[
				{
					"name":"Spico_1566 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_1563 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Spico_1564 biotin carboxylase; acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Spico_1565 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Spico_0519 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Spico_1562 (Acyl-carrier-protein) S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Spico_1560 3-oxoacyl-(acyl-carrier-protein) synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Spico_1561 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1573 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1559 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA\/FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"Spico_1558 reductase\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				}
				]
			},
			{
				"name":"00062 Fatty acid elongation"
			},
			{
				"name":"00071 Fatty acid degradation [PATH:scc00071]",
				"children":[
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00073 Cutin, suberine and wax biosynthesis"
			},
			{
				"name":"00074 Mycolic acid biosynthesis [PATH:scc00074]",
				"children":[
				{
					"name":"Spico_1454 Holo-(acyl-carrier-protein) synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]"
				},
				{
					"name":"Spico_0519 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Spico_1562 (Acyl-carrier-protein) S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				}
				]
			},
			{
				"name":"00100 Steroid biosynthesis"
			},
			{
				"name":"00120 Primary bile acid biosynthesis"
			},
			{
				"name":"00121 Secondary bile acid biosynthesis"
			},
			{
				"name":"00140 Steroid hormone biosynthesis"
			},
			{
				"name":"00561 Glycerolipid metabolism [PATH:scc00561]",
				"children":[
				{
					"name":"Spico_1775 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_1557 glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Spico_0433 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1328 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1853 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_0304 glycosyl transferase group 1\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				},
				{
					"name":"Spico_0769 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Spico_1068 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				}
				]
			},
			{
				"name":"00564 Glycerophospholipid metabolism [PATH:scc00564]",
				"children":[
				{
					"name":"Spico_0433 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1328 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1853 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_0285 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"Spico_1458 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"Spico_0694 phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]"
				},
				{
					"name":"Spico_0221 CDP-diacylglycerol\/glycerol-3-phosphate 3-phosphatidyltransferase\tK00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]"
				},
				{
					"name":"Spico_0300 phospholipase D\/Transphosphatidylase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]"
				},
				{
					"name":"Spico_1080 phospholipase D\/Transphosphatidylase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]"
				},
				{
					"name":"Spico_1438 Glycerol-1-phosphate dehydrogenase (NAD(P)(+))\tK00096 araM; glycerol-1-phosphate dehydrogenase [NAD(P)+] [EC:1.1.1.261]"
				}
				]
			},
			{
				"name":"00565 Ether lipid metabolism"
			},
			{
				"name":"00600 Sphingolipid metabolism [PATH:scc00600]",
				"children":[
				{
					"name":"Spico_0441 serine palmitoyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"Spico_0718 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_1613 glycoside hydrolase family 2 TIM barrel\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_0384 Galactosylceramidase\tK01202 GALC; galactosylceramidase [EC:3.2.1.46]"
				},
				{
					"name":"Spico_0769 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Spico_1068 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Spico_0897 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				}
				]
			},
			{
				"name":"00590 Arachidonic acid metabolism"
			},
			{
				"name":"00591 Linoleic acid metabolism"
			},
			{
				"name":"00592 alpha-Linolenic acid metabolism"
			},
			{
				"name":"01040 Biosynthesis of unsaturated fatty acids"
			}
			]
		},
		{
			"name":"09104 Nucleotide metabolism",
			"children":[
			{
				"name":"00230 Purine metabolism [PATH:scc00230]",
				"children":[
				{
					"name":"Spico_1307 NUDIX hydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				},
				{
					"name":"Spico_1510 metalloenzyme domain protein\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_1046 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"Spico_0862 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"Spico_1245 phosphoribosylamine\/glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]"
				},
				{
					"name":"Spico_0863 Phosphoribosylamine--glycine ligase\tK13713 purCD; fusion protein PurCD [EC:6.3.2.6 6.3.4.13]"
				},
				{
					"name":"Spico_0857 phosphoribosylformylglycinamidine synthase subunit II\tK23269 purL; phosphoribosylformylglycinamidine synthase subunit PurL [EC:6.3.5.3]"
				},
				{
					"name":"Spico_0859 phosphoribosylformylglycinamidine synthase I\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]"
				},
				{
					"name":"Spico_0858 phosphoribosylformylglycinamidine cyclo-ligase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]"
				},
				{
					"name":"Spico_0861 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]"
				},
				{
					"name":"Spico_0860 phosphoribosylaminoimidazole-succinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]"
				},
				{
					"name":"Spico_1299 adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"Spico_1767 IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Spico_0625 adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"Spico_1231 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Spico_1730 HAD-superfamily hydrolase, subfamily IIA\tK02566 nagD; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Spico_0066 inosine guanosine and xanthosine phosphorylase family\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Spico_1108 purine-nucleoside phosphorylase\tK03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Spico_1294 hypoxanthine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]"
				},
				{
					"name":"Spico_0448 IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"Spico_0797 Nucleoside-triphosphatase rdgB\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]"
				},
				{
					"name":"Spico_1324 GMP synthase (glutamine-hydrolyzing)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"Spico_1766 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_1765 ribonucleotide reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_0846 ribonucleoside-triphosphate reductase class III catalytic subunit\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"Spico_0681 metal-dependent phosphohydrolase HD sub domain protein\tK01129 dgt; dGTPase [EC:3.1.5.1]"
				},
				{
					"name":"Spico_1076 (p)ppGpp synthetase I, SpoT\/RelA\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"Spico_1296 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Spico_0117 adenosine deaminase\tK01488 add; adenosine deaminase [EC:3.5.4.4]"
				},
				{
					"name":"Spico_1688 Conserved hypothetical protein CHP00282\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]"
				},
				{
					"name":"Spico_0727 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				}
				]
			},
			{
				"name":"00240 Pyrimidine metabolism [PATH:scc00240]",
				"children":[
				{
					"name":"Spico_1731 carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_1732 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_1029 aspartate carbamoyltransferase\tK00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2]"
				},
				{
					"name":"Spico_1025 dihydroorotase, putative\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"Spico_1026 dihydroorotate dehydrogenase family protein\tK02823 pyrDII; dihydroorotate dehydrogenase electron transfer subunit"
				},
				{
					"name":"Spico_1028 orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]"
				},
				{
					"name":"Spico_1027 orotidine 5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]"
				},
				{
					"name":"Spico_1056 uridylate kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]"
				},
				{
					"name":"Spico_0689 Septum formation protein Maf\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]"
				},
				{
					"name":"Spico_1784 CTP synthase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]"
				},
				{
					"name":"Spico_0612 Cytidylate kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]"
				},
				{
					"name":"Spico_0906 Cytidylate kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]"
				},
				{
					"name":"Spico_0967 uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]"
				},
				{
					"name":"Spico_1228 AAA ATPase\tK00876 udk; uridine kinase [EC:2.7.1.48]"
				},
				{
					"name":"Spico_1231 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Spico_1730 HAD-superfamily hydrolase, subfamily IIA\tK02566 nagD; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Spico_0460 uridine phosphorylase\tK00757 udp; uridine phosphorylase [EC:2.4.2.3]"
				},
				{
					"name":"Spico_0728 uracil phosphoribosyltransferase\tK00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Spico_1688 Conserved hypothetical protein CHP00282\tK09769 ymdB; 2',3'-cyclic-nucleotide 2'-phosphodiesterase [EC:3.1.4.16]"
				},
				{
					"name":"Spico_0846 ribonucleoside-triphosphate reductase class III catalytic subunit\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"Spico_1766 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_1765 ribonucleotide reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_1311 dCMP deaminase\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"Spico_0587 Thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]"
				},
				{
					"name":"Spico_0600 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"Spico_0037 thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]"
				},
				{
					"name":"Spico_1594 Thymidylate synthase thyX\tK03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]"
				}
				]
			}
			]
		},
		{
			"name":"09105 Amino acid metabolism",
			"children":[
			{
				"name":"00250 Alanine, aspartate and glutamate metabolism [PATH:scc00250]",
				"children":[
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_0270 Asparaginase\/glutaminase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"Spico_1551 aspartate-ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"Spico_1769 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"Spico_0711 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Spico_1052 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Spico_1296 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Spico_1299 adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"Spico_1029 aspartate carbamoyltransferase\tK00608 pyrBI; aspartate carbamoyltransferase [EC:2.1.3.2]"
				},
				{
					"name":"Spico_0573 glutamate synthase (NADH) large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_0372 Glutamate synthase (NADPH)\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_0572 glutamate synthase (NADH) small subunit\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_1117 sulfide dehydrogenase (flavoprotein) subunit SudA\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_0375 glutamate dehydrogenase (NADP)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1768 glutamate dehydrogenase (NAD)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_1731 carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_1732 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_0859 phosphoribosylformylglycinamidine synthase I\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]"
				},
				{
					"name":"Spico_0862 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				}
				]
			},
			{
				"name":"00260 Glycine, serine and threonine metabolism [PATH:scc00260]",
				"children":[
				{
					"name":"Spico_0268 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Spico_0429 Aspartate kinase., Homoserine dehydrogenase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Spico_1319 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Spico_0290 phosphoserine phosphatase\/homoserine phosphotransferase bifunctional protein\tK02203 thrH; phosphoserine \/ homoserine phosphotransferase [EC:3.1.3.3 2.7.1.39]"
				},
				{
					"name":"Spico_0430 threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				},
				{
					"name":"Spico_1432 Threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]"
				},
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Spico_1775 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Spico_0424 phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"Spico_0402 phosphoserine aminotransferase apoenzyme\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Spico_1064 2-amino-3-ketobutyrate coenzyme A ligase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Spico_1215 glycine dehydrogenase (decarboxylating) alpha subunit\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1214 glycine dehydrogenase (decarboxylating) beta subunit\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1217 aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1216 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"Spico_0076 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"Spico_1620 L-threonine ammonia-lyase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"Spico_0870 Tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				}
				]
			},
			{
				"name":"00270 Cysteine and methionine metabolism [PATH:scc00270]",
				"children":[
				{
					"name":"Spico_1008 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Spico_1758 cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"Spico_1433 Cystathionine beta-lyase\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"Spico_0502 methionine synthase (B12-independent)\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"Spico_0024 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Spico_1411 MTA\/SAH nucleosidase\tK01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]"
				},
				{
					"name":"Spico_0979 S-adenosylhomocysteine deaminase\tK12960 mtaD; 5-methylthioadenosine\/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]"
				},
				{
					"name":"Spico_0025 methylthioribose-1-phosphate isomerase\tK08963 mtnA; methylthioribose-1-phosphate isomerase [EC:5.3.1.23]"
				},
				{
					"name":"Spico_0218 putative GAF sensor protein\tK08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]"
				},
				{
					"name":"Spico_1410 quorum-sensing autoinducer 2 (AI-2), LuxS\tK07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]"
				},
				{
					"name":"Spico_0268 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Spico_0429 Aspartate kinase., Homoserine dehydrogenase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Spico_1319 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Spico_1472 homoserine O-succinyltransferase\tK00651 metA; homoserine O-succinyltransferase\/O-acetyltransferase [EC:2.3.1.46 2.3.1.31]"
				},
				{
					"name":"Spico_1380 Cystathionine gamma-lyase\tK01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]"
				},
				{
					"name":"Spico_1473 O-acetylhomoserine sulfhydrolase\tK01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]"
				},
				{
					"name":"Spico_1331 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1617 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1643 L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"Spico_0076 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"Spico_0402 phosphoserine aminotransferase apoenzyme\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00280 Valine, leucine and isoleucine degradation [PATH:scc00280]",
				"children":[
				{
					"name":"Spico_1331 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1617 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1292 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1651 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:scc00290]",
				"children":[
				{
					"name":"Spico_1620 L-threonine ammonia-lyase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"Spico_0324 3-isopropylmalate dehydratase, large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Spico_0325 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Spico_0326 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				},
				{
					"name":"Spico_0328 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0320 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0321 ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"Spico_0327 dihydroxyacid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"Spico_1331 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1617 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_0322 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				},
				{
					"name":"Spico_0323 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00300 Lysine biosynthesis [PATH:scc00300]",
				"children":[
				{
					"name":"Spico_0268 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Spico_0429 Aspartate kinase., Homoserine dehydrogenase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Spico_1319 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Spico_0779 dihydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Spico_0780 Dihydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				},
				{
					"name":"Spico_1771 Acetylornithine\/succinyldiaminopimelate aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"Spico_0778 LL-diaminopimelate aminotransferase apoenzyme\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"Spico_0777 diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				},
				{
					"name":"Spico_0910 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Spico_0653 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				}
				]
			},
			{
				"name":"00310 Lysine degradation [PATH:scc00310]",
				"children":[
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1338 lysine 2,3-aminomutase YodO family protein\tK01843 kamA; lysine 2,3-aminomutase [EC:5.4.3.2]"
				},
				{
					"name":"Spico_1043 protein of unknown function DUF849\tK18013 kce; 3-keto-5-aminohexanoate cleavage enzyme [EC:2.3.1.247]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00220 Arginine biosynthesis [PATH:scc00220]",
				"children":[
				{
					"name":"Spico_0229 ornithine carbamoyltransferase\tK00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]"
				},
				{
					"name":"Spico_0711 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Spico_1052 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Spico_0859 phosphoribosylformylglycinamidine synthase I\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_1731 carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_1732 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Spico_0375 glutamate dehydrogenase (NADP)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1768 glutamate dehydrogenase (NAD)\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1773 N-acetylglutamate synthase; glutamate N-acetyltransferase\tK00620 argJ; glutamate N-acetyltransferase \/ amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]"
				},
				{
					"name":"Spico_1772 N-acetylglutamate kinase\tK00930 argB; acetylglutamate kinase [EC:2.7.2.8]"
				},
				{
					"name":"Spico_1774 N-acetyl-gamma-glutamyl-phosphate reductase\tK00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]"
				},
				{
					"name":"Spico_1771 Acetylornithine\/succinyldiaminopimelate aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				}
				]
			},
			{
				"name":"00330 Arginine and proline metabolism [PATH:scc00330]",
				"children":[
				{
					"name":"Spico_1778 Hydantoinase\/oxoprolinase\tK01473 hyuA; N-methylhydantoinase A [EC:3.5.2.14]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_0914 pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]"
				},
				{
					"name":"Spico_0919 Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"Spico_0920 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				},
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				}
				]
			},
			{
				"name":"00340 Histidine metabolism [PATH:scc00340]",
				"children":[
				{
					"name":"Spico_1427 ATP phosphoribosyltransferase\tK00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]"
				},
				{
					"name":"Spico_1420 Phosphoribosyl-ATP pyrophosphatase\tK11755 hisIE; phosphoribosyl-AMP cyclohydrolase \/ phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]"
				},
				{
					"name":"Spico_1422 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase\tK01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]"
				},
				{
					"name":"Spico_1423 imidazole glycerol phosphate synthase subunit hisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]"
				},
				{
					"name":"Spico_1421 Imidazole glycerol phosphate synthase subunit hisF\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]"
				},
				{
					"name":"Spico_1424 Imidazoleglycerol-phosphate dehydratase\tK01089 hisB; imidazoleglycerol-phosphate dehydratase \/ histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Spico_1635 histidinol phosphate phosphatase HisJ family\tK04486 hisK; histidinol-phosphatase (PHP family) [EC:3.1.3.15]"
				},
				{
					"name":"Spico_1426 histidinol dehydrogenase\tK00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00350 Tyrosine metabolism [PATH:scc00350]",
				"children":[
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				}
				]
			},
			{
				"name":"00360 Phenylalanine metabolism [PATH:scc00360]",
				"children":[
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			},
			{
				"name":"00380 Tryptophan metabolism [PATH:scc00380]",
				"children":[
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_0266 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				}
				]
			},
			{
				"name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:scc00400]",
				"children":[
				{
					"name":"Spico_0877 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]"
				},
				{
					"name":"Spico_1823 phospho-2-dehydro-3-deoxyheptonate aldolase\tK03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]"
				},
				{
					"name":"Spico_0526 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]"
				},
				{
					"name":"Spico_0687 3-dehydroquinate dehydratase\tK13832 aroDE; 3-dehydroquinate dehydratase \/ shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25]"
				},
				{
					"name":"Spico_0683 Shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]"
				},
				{
					"name":"Spico_1431 3-phosphoshikimate 1-carboxyvinyltransferase\tK00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]"
				},
				{
					"name":"Spico_0684 chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]"
				},
				{
					"name":"Spico_0870 Tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				},
				{
					"name":"Spico_0550 chorismate mutase\tK06208 aroH; chorismate mutase [EC:5.4.99.5]"
				},
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			}
			]
		},
		{
			"name":"09106 Metabolism of other amino acids",
			"children":[
			{
				"name":"00410 beta-Alanine metabolism",
				"children":[
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00430 Taurine and hypotaurine metabolism [PATH:scc00430]",
				"children":[
				{
					"name":"Spico_1011 phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"Spico_0875 acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				}
				]
			},
			{
				"name":"00440 Phosphonate and phosphinate metabolism",
				"children":[
				{
					"name":"Spico_1345 beta-lactamase domain protein\tK06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]"
				}
				]
			},
			{
				"name":"00450 Selenocompound metabolism [PATH:scc00450]",
				"children":[
				{
					"name":"Spico_1380 Cystathionine gamma-lyase\tK01739 metB; cystathionine gamma-synthase [EC:2.5.1.48]"
				},
				{
					"name":"Spico_1433 Cystathionine beta-lyase\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"Spico_0502 methionine synthase (B12-independent)\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"Spico_1761 cysteine desulfurase\tK11717 sufS; cysteine desulfurase \/ selenocysteine lyase [EC:2.8.1.7 4.4.1.16]"
				},
				{
					"name":"Spico_0934 thioredoxin reductase (NADPH)\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"Spico_0705 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				}
				]
			},
			{
				"name":"00460 Cyanoamino acid metabolism [PATH:scc00460]",
				"children":[
				{
					"name":"Spico_0720 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0747 broad-specificity cellobiase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0770 Beta-glucosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0270 Asparaginase\/glutaminase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"Spico_1551 aspartate-ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				}
				]
			},
			{
				"name":"00470 D-Amino acid metabolism [PATH:scc00470]",
				"children":[
				{
					"name":"Spico_0911 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Spico_0859 phosphoribosylformylglycinamidine synthase I\tK23265 purQ; phosphoribosylformylglycinamidine synthase subunit PurQ \/ glutaminase [EC:6.3.5.3 3.5.1.2]"
				},
				{
					"name":"Spico_0703 UDP-N-acetylmuramoylalanine\/D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Spico_0777 diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				}
				]
			},
			{
				"name":"00480 Glutathione metabolism [PATH:scc00480]",
				"children":[
				{
					"name":"Spico_1851 aminoacyl-histidine dipeptidase\tK01270 pepD; dipeptidase D [EC:3.4.13.-]"
				}
				]
			}
			]
		},
		{
			"name":"09107 Glycan biosynthesis and metabolism",
			"children":[
			{
				"name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:scc00520]",
				"children":[
				{
					"name":"Spico_0027 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Spico_0378 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Spico_0897 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Spico_1850 N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_1488 Phosphoglucosamine mutase\tK03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]"
				},
				{
					"name":"Spico_0284 glucosamine-6-phosphate deaminase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"Spico_0946 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"Spico_1786 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0010 glucose-6-phosphate isomerase\tK06859 pgi1; glucose-6-phosphate isomerase, archaeal [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0280 mannose-6-phosphate isomerase, class I\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]"
				},
				{
					"name":"Spico_0340 Alpha-N-arabinofuranosidase\tK01209 abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55]"
				},
				{
					"name":"Spico_0671 Xylan 1,4-beta-xylosidase\tK01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37]"
				},
				{
					"name":"Spico_0724 Xylan 1,4-beta-xylosidase\tK22268 xylA; xylan 1,4-beta-xylosidase [EC:3.2.1.37]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_0431 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_1232 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_0957 UDP-galactose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"Spico_0956 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"Spico_0936 Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				}
				]
			},
			{
				"name":"00541 Biosynthesis of various nucleotide sugars [PATH:scc00541]",
				"children":[
				{
					"name":"Spico_1623 sugar isomerase (SIS)\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]"
				},
				{
					"name":"Spico_1254 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00510 N-Glycan biosynthesis"
			},
			{
				"name":"00513 Various types of N-glycan biosynthesis"
			},
			{
				"name":"00512 Mucin type O-glycan biosynthesis"
			},
			{
				"name":"00515 Mannose type O-glycan biosynthesis"
			},
			{
				"name":"00514 Other types of O-glycan biosynthesis"
			},
			{
				"name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate"
			},
			{
				"name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin"
			},
			{
				"name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate"
			},
			{
				"name":"00531 Glycosaminoglycan degradation"
			},
			{
				"name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
			},
			{
				"name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series"
			},
			{
				"name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series"
			},
			{
				"name":"00604 Glycosphingolipid biosynthesis - ganglio series"
			},
			{
				"name":"00511 Other glycan degradation [PATH:scc00511]",
				"children":[
				{
					"name":"Spico_0718 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_1613 glycoside hydrolase family 2 TIM barrel\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Spico_0897 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Spico_1282 Alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"Spico_0890 Beta-mannosidase\tK01192 E3.2.1.25; beta-mannosidase [EC:3.2.1.25]"
				},
				{
					"name":"Spico_0365 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				}
				]
			},
			{
				"name":"00540 Lipopolysaccharide biosynthesis"
			},
			{
				"name":"00542 O-Antigen repeat unit biosynthesis"
			},
			{
				"name":"00550 Peptidoglycan biosynthesis [PATH:scc00550]",
				"children":[
				{
					"name":"Spico_0027 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Spico_0378 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Spico_0908 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"Spico_0703 UDP-N-acetylmuramoylalanine\/D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Spico_0910 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Spico_0911 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Spico_0653 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"Spico_0693 Undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"Spico_0652 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Spico_0638 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"Spico_0651 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Spico_0641 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				}
				]
			},
			{
				"name":"00552 Teichoic acid biosynthesis [PATH:scc00552]",
				"children":[
				{
					"name":"Spico_0304 glycosyl transferase group 1\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				}
				]
			},
			{
				"name":"00571 Lipoarabinomannan (LAM) biosynthesis"
			},
			{
				"name":"00572 Arabinogalactan biosynthesis - Mycobacterium"
			},
			{
				"name":"00543 Exopolysaccharide biosynthesis [PATH:scc00543]",
				"children":[
				{
					"name":"Spico_1008 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				}
				]
			}
			]
		},
		{
			"name":"09108 Metabolism of cofactors and vitamins",
			"children":[
			{
				"name":"00730 Thiamine metabolism [PATH:scc00730]",
				"children":[
				{
					"name":"Spico_0525 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Spico_0524 tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"Spico_0454 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Spico_0548 thiamine pyrophosphokinase\tK00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]"
				},
				{
					"name":"Spico_0727 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				}
				]
			},
			{
				"name":"00740 Riboflavin metabolism [PATH:scc00740]",
				"children":[
				{
					"name":"Spico_0597 FAD synthetase\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]"
				},
				{
					"name":"Spico_1094 nitroreductase\tK19286 nfrA2; FMN reductase [NAD(P)H] [EC:1.5.1.39]"
				},
				{
					"name":"Spico_1307 NUDIX hydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				}
				]
			},
			{
				"name":"00750 Vitamin B6 metabolism [PATH:scc00750]",
				"children":[
				{
					"name":"Spico_1059 Phosphomethylpyrimidine kinase type-1\tK00868 pdxK; pyridoxine kinase [EC:2.7.1.35]"
				},
				{
					"name":"Spico_0402 phosphoserine aminotransferase apoenzyme\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Spico_0430 threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				}
				]
			},
			{
				"name":"00760 Nicotinate and nicotinamide metabolism [PATH:scc00760]",
				"children":[
				{
					"name":"Spico_0916 nicotinate phosphoribosyltransferase\tK00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]"
				},
				{
					"name":"Spico_0066 inosine guanosine and xanthosine phosphorylase family\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Spico_1108 purine-nucleoside phosphorylase\tK03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Spico_1231 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Spico_1730 HAD-superfamily hydrolase, subfamily IIA\tK02566 nagD; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Spico_1000 nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]"
				},
				{
					"name":"Spico_1349 NAD+ synthetase\tK01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]"
				},
				{
					"name":"Spico_0486 NAD-dependent deacetylase\tK12410 cobB; NAD-dependent protein deacetylase\/lipoamidase [EC:2.3.1.286 2.3.1.313]"
				},
				{
					"name":"Spico_0661 inorganic polyphosphate\/ATP-NAD kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]"
				},
				{
					"name":"Spico_1503 NAD(P)(+) transhydrogenase-like protein\tK00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]"
				},
				{
					"name":"Spico_1504 NAD(P)(+) transhydrogenase (AB-specific)\tK00324 pntA; proton-translocating NAD(P)+ transhydrogenase subunit alpha [EC:7.1.1.1]"
				},
				{
					"name":"Spico_1502 NAD(P)(+) transhydrogenase (AB-specific)\tK00325 pntB; proton-translocating NAD(P)+ transhydrogenase subunit beta [EC:7.1.1.1]"
				}
				]
			},
			{
				"name":"00770 Pantothenate and CoA biosynthesis [PATH:scc00770]",
				"children":[
				{
					"name":"Spico_0328 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0320 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Spico_0321 ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"Spico_0327 dihydroxyacid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"Spico_1085 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]"
				},
				{
					"name":"Spico_1314 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]"
				},
				{
					"name":"Spico_0623 putative transcriptional acitvator, Baf family\tK03525 coaX; type III pantothenate kinase [EC:2.7.1.33]"
				},
				{
					"name":"Spico_0517 Phosphopantetheine adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]"
				},
				{
					"name":"Spico_1343 Dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]"
				},
				{
					"name":"Spico_1454 Holo-(acyl-carrier-protein) synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]"
				},
				{
					"name":"Spico_1331 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1617 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00780 Biotin metabolism [PATH:scc00780]",
				"children":[
				{
					"name":"Spico_1560 3-oxoacyl-(acyl-carrier-protein) synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Spico_1561 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1573 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1559 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA\/FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"Spico_1006 biotin\/acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Spico_0441 serine palmitoyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				}
				]
			},
			{
				"name":"00785 Lipoic acid metabolism [PATH:scc00785]",
				"children":[
				{
					"name":"Spico_1213 lipoyltransferase and lipoate-protein ligase\tK03800 lplA; lipoate---protein ligase [EC:6.3.1.20]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1653 Dihydrolipoyllysine-residue acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Spico_1292 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1651 Pyruvate dehydrogenase (acetyl-transferring)\tK11381 bkdA; 2-oxoisovalerate dehydrogenase E1 component [EC:1.2.4.4]"
				},
				{
					"name":"Spico_1215 glycine dehydrogenase (decarboxylating) alpha subunit\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1214 glycine dehydrogenase (decarboxylating) beta subunit\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1217 aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Spico_1216 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				}
				]
			},
			{
				"name":"00790 Folate biosynthesis [PATH:scc00790]",
				"children":[
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Spico_0900 FolC bifunctional protein\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]"
				},
				{
					"name":"Spico_0410 Radical SAM domain protein\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				},
				{
					"name":"Spico_0411 Radical SAM domain protein\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				}
				]
			},
			{
				"name":"00670 One carbon pool by folate [PATH:scc00670]",
				"children":[
				{
					"name":"Spico_0271 Formate-tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"Spico_0483 5; methenyltetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Spico_1767 IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Spico_1217 aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Spico_1594 Thymidylate synthase thyX\tK03465 thyX; thymidylate synthase (FAD) [EC:2.1.1.148]"
				},
				{
					"name":"Spico_0503 5,10-methylenetetrahydrofolate reductase\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"Spico_1115 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"Spico_0024 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Spico_1215 glycine dehydrogenase (decarboxylating) alpha subunit\tK00282 gcvPA; glycine cleavage system P protein (glycine dehydrogenase) subunit 1 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1214 glycine dehydrogenase (decarboxylating) beta subunit\tK00283 gcvPB; glycine cleavage system P protein (glycine dehydrogenase) subunit 2 [EC:1.4.4.2]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_1216 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				}
				]
			},
			{
				"name":"00830 Retinol metabolism"
			},
			{
				"name":"00860 Porphyrin metabolism [PATH:scc00860]",
				"children":[
				{
					"name":"Spico_0982 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Spico_0855 Glutamyl-tRNA reductase\tK02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]"
				}
				]
			},
			{
				"name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:scc00130]",
				"children":[
				{
					"name":"Spico_0071 hypothetical protein\tK03809 wrbA; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]"
				}
				]
			}
			]
		},
		{
			"name":"09109 Metabolism of terpenoids and polyketides",
			"children":[
			{
				"name":"00900 Terpenoid backbone biosynthesis [PATH:scc00900]",
				"children":[
				{
					"name":"Spico_0695 1-deoxy-D-xylulose 5-phosphate reductoisomerase\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]"
				},
				{
					"name":"Spico_1599 4-diphosphocytidyl-2C-methyl-D-erythritol synthase\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]"
				},
				{
					"name":"Spico_0976 4-diphosphocytidyl-2-C-methyl-D-erythritolkinase\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]"
				},
				{
					"name":"Spico_1600 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]"
				},
				{
					"name":"Spico_0464 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]"
				},
				{
					"name":"Spico_0216 4-hydroxy-3-methylbut-2-enyl diphosphate reductase\tK03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]"
				},
				{
					"name":"Spico_0693 Undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				}
				]
			},
			{
				"name":"00902 Monoterpenoid biosynthesis"
			},
			{
				"name":"00909 Sesquiterpenoid and triterpenoid biosynthesis"
			},
			{
				"name":"00904 Diterpenoid biosynthesis"
			},
			{
				"name":"00906 Carotenoid biosynthesis"
			},
			{
				"name":"00905 Brassinosteroid biosynthesis"
			},
			{
				"name":"00981 Insect hormone biosynthesis"
			},
			{
				"name":"00908 Zeatin biosynthesis"
			},
			{
				"name":"00903 Limonene degradation",
				"children":[
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00907 Pinene, camphor and geraniol degradation"
			},
			{
				"name":"01052 Type I polyketide structures"
			},
			{
				"name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides"
			},
			{
				"name":"01051 Biosynthesis of ansamycins",
				"children":[
				{
					"name":"Spico_0121 transketolase subunit A\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Spico_0122 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				}
				]
			},
			{
				"name":"01059 Biosynthesis of enediyne antibiotics"
			},
			{
				"name":"01056 Biosynthesis of type II polyketide backbone"
			},
			{
				"name":"01057 Biosynthesis of type II polyketide products"
			},
			{
				"name":"00253 Tetracycline biosynthesis"
			},
			{
				"name":"00523 Polyketide sugar unit biosynthesis",
				"children":[
				{
					"name":"Spico_1254 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"01054 Nonribosomal peptide structures"
			},
			{
				"name":"01053 Biosynthesis of siderophore group nonribosomal peptides"
			},
			{
				"name":"01055 Biosynthesis of vancomycin group antibiotics",
				"children":[
				{
					"name":"Spico_1254 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			}
			]
		},
		{
			"name":"09110 Biosynthesis of other secondary metabolites",
			"children":[
			{
				"name":"00940 Phenylpropanoid biosynthesis"
			},
			{
				"name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis"
			},
			{
				"name":"00941 Flavonoid biosynthesis"
			},
			{
				"name":"00944 Flavone and flavonol biosynthesis"
			},
			{
				"name":"00942 Anthocyanin biosynthesis"
			},
			{
				"name":"00943 Isoflavonoid biosynthesis"
			},
			{
				"name":"00946 Degradation of flavonoids [PATH:scc00946]",
				"children":[
				{
					"name":"Spico_0720 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0747 broad-specificity cellobiase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0770 Beta-glucosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				}
				]
			},
			{
				"name":"00901 Indole alkaloid biosynthesis"
			},
			{
				"name":"00403 Indole diterpene alkaloid biosynthesis"
			},
			{
				"name":"00950 Isoquinoline alkaloid biosynthesis"
			},
			{
				"name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis"
			},
			{
				"name":"00996 Biosynthesis of various alkaloids"
			},
			{
				"name":"00232 Caffeine metabolism"
			},
			{
				"name":"00965 Betalain biosynthesis"
			},
			{
				"name":"00966 Glucosinolate biosynthesis"
			},
			{
				"name":"00402 Benzoxazinoid biosynthesis"
			},
			{
				"name":"00311 Penicillin and cephalosporin biosynthesis"
			},
			{
				"name":"00332 Carbapenem biosynthesis [PATH:scc00332]",
				"children":[
				{
					"name":"Spico_0919 Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"Spico_0920 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				}
				]
			},
			{
				"name":"00261 Monobactam biosynthesis [PATH:scc00261]",
				"children":[
				{
					"name":"Spico_0268 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Spico_0429 Aspartate kinase., Homoserine dehydrogenase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Spico_1319 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Spico_0779 dihydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Spico_0780 Dihydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				}
				]
			},
			{
				"name":"00331 Clavulanic acid biosynthesis"
			},
			{
				"name":"00521 Streptomycin biosynthesis [PATH:scc00521]",
				"children":[
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1017 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Spico_0082 myo-inositol 2-dehydrogenase\tK00010 iolG; myo-inositol 2-dehydrogenase \/ D-chiro-inositol 1-dehydrogenase [EC:1.1.1.18 1.1.1.369]"
				},
				{
					"name":"Spico_1254 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00524 Neomycin, kanamycin and gentamicin biosynthesis [PATH:scc00524]",
				"children":[
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_0094 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Spico_1622 Glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				}
				]
			},
			{
				"name":"00525 Acarbose and validamycin biosynthesis",
				"children":[
				{
					"name":"Spico_1254 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00401 Novobiocin biosynthesis [PATH:scc00401]",
				"children":[
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			},
			{
				"name":"00404 Staurosporine biosynthesis"
			},
			{
				"name":"00405 Phenazine biosynthesis"
			},
			{
				"name":"00333 Prodigiosin biosynthesis",
				"children":[
				{
					"name":"Spico_1562 (Acyl-carrier-protein) S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Spico_1561 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1573 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				}
				]
			},
			{
				"name":"00254 Aflatoxin biosynthesis"
			},
			{
				"name":"00975 Biosynthesis of various siderophores"
			},
			{
				"name":"00998 Biosynthesis of various antibiotics",
				"children":[
				{
					"name":"Spico_0519 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				}
				]
			},
			{
				"name":"00999 Biosynthesis of various plant secondary metabolites [PATH:scc00999]",
				"children":[
				{
					"name":"Spico_0024 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Spico_0687 3-dehydroquinate dehydratase\tK13832 aroDE; 3-dehydroquinate dehydratase \/ shikimate dehydrogenase [EC:4.2.1.10 1.1.1.25]"
				},
				{
					"name":"Spico_0720 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0747 broad-specificity cellobiase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Spico_0770 Beta-glucosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				}
				]
			},
			{
				"name":"00997 Biosynthesis of various other secondary metabolites"
			}
			]
		},
		{
			"name":"09111 Xenobiotics biodegradation and metabolism",
			"children":[
			{
				"name":"00362 Benzoate degradation",
				"children":[
				{
					"name":"Spico_0318 sodium ion-translocating decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1173 glutaconyl-CoA decarboxylase beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				}
				]
			},
			{
				"name":"00627 Aminobenzoate degradation"
			},
			{
				"name":"00364 Fluorobenzoate degradation"
			},
			{
				"name":"00625 Chloroalkane and chloroalkene degradation [PATH:scc00625]",
				"children":[
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"Spico_0892 Aldehyde Dehydrogenase\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"Spico_1429 HAD superfamily (subfamily IA) hydrolase, TIGR02254\tK01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]"
				}
				]
			},
			{
				"name":"00361 Chlorocyclohexane and chlorobenzene degradation",
				"children":[
				{
					"name":"Spico_1429 HAD superfamily (subfamily IA) hydrolase, TIGR02254\tK01560 E3.8.1.2; 2-haloacid dehalogenase [EC:3.8.1.2]"
				}
				]
			},
			{
				"name":"00623 Toluene degradation"
			},
			{
				"name":"00622 Xylene degradation"
			},
			{
				"name":"00633 Nitrotoluene degradation"
			},
			{
				"name":"00642 Ethylbenzene degradation"
			},
			{
				"name":"00643 Styrene degradation"
			},
			{
				"name":"00791 Atrazine degradation"
			},
			{
				"name":"00930 Caprolactam degradation"
			},
			{
				"name":"00363 Bisphenol degradation"
			},
			{
				"name":"00621 Dioxin degradation"
			},
			{
				"name":"00626 Naphthalene degradation [PATH:scc00626]",
				"children":[
				{
					"name":"Spico_0344 alcohol dehydrogenase AdhE; acetaldehyde dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				}
				]
			},
			{
				"name":"00624 Polycyclic aromatic hydrocarbon degradation"
			},
			{
				"name":"00365 Furfural degradation"
			},
			{
				"name":"00984 Steroid degradation"
			},
			{
				"name":"00980 Metabolism of xenobiotics by cytochrome P450"
			},
			{
				"name":"00982 Drug metabolism - cytochrome P450"
			},
			{
				"name":"00983 Drug metabolism - other enzymes"
			}
			]
		},
		{
			"name":"09112 Not included in regular maps",
			"children":[
			{
				"name":"09113 Global maps only"
			}
			]
		}
		]
	},
	{
		"name":"09120 Genetic Information Processing",
		"children":[
		{
			"name":"09121 Transcription",
			"children":[
			{
				"name":"03020 RNA polymerase [PATH:scc03020]",
				"children":[
				{
					"name":"Spico_1722 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1721 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1691 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				}
				]
			},
			{
				"name":"03022 Basal transcription factors",
				"children":[
				{
					"name":"Spico_0685 helicase domain protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03040 Spliceosome"
			}
			]
		},
		{
			"name":"09122 Translation",
			"children":[
			{
				"name":"03010 Ribosome [PATH:scc03010]",
				"children":[
				{
					"name":"Spico_R0002 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0025 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0031 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0004 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0023 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0029 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0005 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0022 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0028 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_0613 RNA binding S1 domain protein\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"Spico_0690 SSU ribosomal protein S2P\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"Spico_1710 SSU ribosomal protein S3P\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"Spico_1692 SSU ribosomal protein S4P\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"Spico_1699 SSU ribosomal protein S5P\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"Spico_0702 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"Spico_1719 SSU ribosomal protein S7P\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"Spico_1702 SSU ribosomal protein S8P\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"Spico_1191 SSU ribosomal protein S9P\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"Spico_1717 SSU ribosomal protein S10P\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"Spico_1693 SSU ribosomal protein S11P\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"Spico_1720 SSU ribosomal protein S12P\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"Spico_1694 SSU ribosomal protein S13P\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"Spico_1703 SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"Spico_0598 SSU ribosomal protein S15P\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"Spico_0510 SSU ribosomal protein S16P\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"Spico_1707 SSU ribosomal protein S17P\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"Spico_0700 SSU ribosomal protein S18P\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"Spico_1712 SSU ribosomal protein S19P\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"Spico_1238 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"Spico_0398 SSU ribosomal protein S21P\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"Spico_1725 LSU ribosomal protein L1P\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"Spico_1713 LSU ribosomal protein L2P\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"Spico_1716 LSU ribosomal protein L3P\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"Spico_1715 LSU ribosomal protein L4P\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"Spico_1704 LSU ribosomal protein L5P\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"Spico_1701 LSU ribosomal protein L6P\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"Spico_0698 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"Spico_1724 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"Spico_1726 LSU ribosomal protein L11P\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"Spico_1723 LSU ribosomal protein L12P\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"Spico_1192 LSU ribosomal protein L13P\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"Spico_1706 LSU ribosomal protein L14P\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"Spico_1697 LSU ribosomal protein L15P\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"Spico_1709 LSU ribosomal protein L16P\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"Spico_1690 LSU ribosomal protein L17P\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"Spico_1700 LSU ribosomal protein L18P\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"Spico_0514 LSU ribosomal protein L19P\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"Spico_0929 LSU ribosomal protein L20P\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"Spico_1003 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"Spico_1711 LSU ribosomal protein L22P\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"Spico_1714 Ribosomal protein L25\/L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"Spico_1705 LSU ribosomal protein L24P\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"Spico_0973 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"Spico_1002 LSU ribosomal protein L27P\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"Spico_0428 LSU ribosomal protein L28P\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"Spico_1708 LSU ribosomal protein L29P\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"Spico_1698 LSU ribosomal protein L30P\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"Spico_1233 LSU ribosomal protein L31P\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"Spico_0518 LSU ribosomal protein L32P\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"Spico_1729 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"Spico_0005 LSU ribosomal protein L34P\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"Spico_0928 LSU ribosomal protein L35P\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"Spico_1695 LSU ribosomal protein L36P\tK02919 RP-L36; large subunit ribosomal protein L36"
				}
				]
			},
			{
				"name":"00970 Aminoacyl-tRNA biosynthesis [PATH:scc00970]",
				"children":[
				{
					"name":"Spico_R0001 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0024 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0030 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0049 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0034 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0038 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0047 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0056 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0042 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"Spico_R0007 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Spico_R0048 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Spico_R0020 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Spico_R0043 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Spico_R0019 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Spico_R0026 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Spico_R0006 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0014 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0037 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0033 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"Spico_R0003 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Spico_R0008 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0036 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0039 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0050 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0027 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Spico_R0035 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Spico_R0012 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0046 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0051 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0045 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"Spico_R0009 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0032 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0040 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0054 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0055 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0057 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0058 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0015 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0021 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0053 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0052 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"Spico_R0018 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"Spico_R0010 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_R0011 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_R0013 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_0982 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Spico_0948 glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Spico_1103 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_1301 Alanyl-tRNA synthetase, class IIc\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_0126 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Spico_0886 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Spico_0981 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Spico_0219 Ser-tRNA(Thr) hydrolase; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Spico_0915 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Spico_0379 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Spico_0705 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Spico_1447 Methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]"
				},
				{
					"name":"Spico_0387 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0420 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_1492 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0089 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Spico_0522 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Spico_1489 lysyl-tRNA synthetase\tK04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]"
				},
				{
					"name":"Spico_1005 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Spico_0119 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Spico_0528 histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Spico_1289 phenylalanyl-tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_1288 phenylalanyl-tRNA synthetase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_0980 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Spico_1376 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"03013 Nucleocytoplasmic transport"
			},
			{
				"name":"03015 mRNA surveillance pathway"
			},
			{
				"name":"03008 Ribosome biogenesis in eukaryotes",
				"children":[
				{
					"name":"Spico_0520 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			}
			]
		},
		{
			"name":"09123 Folding, sorting and degradation",
			"children":[
			{
				"name":"03060 Protein export [PATH:scc03060]",
				"children":[
				{
					"name":"Spico_1696 protein translocase subunit secY\/sec61 alpha\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Spico_1728 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Spico_0474 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Spico_0214 protein-export membrane protein SecD\tK03072 secD; preprotein translocase subunit SecD"
				},
				{
					"name":"Spico_0213 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Spico_0007 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Spico_0639 protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Spico_0509 signal recognition particle subunit FFH\/SRP54 (srp54)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Spico_R0059 RNA component of signal recognition particle\tK01983 ffs; signal recognition particle 4.5S RNA"
				},
				{
					"name":"Spico_0539 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Spico_0580 signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"Spico_0148 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				}
				]
			},
			{
				"name":"04141 Protein processing in endoplasmic reticulum [PATH:scc04141]",
				"children":[
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Spico_1119 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				}
				]
			},
			{
				"name":"04130 SNARE interactions in vesicular transport"
			},
			{
				"name":"04120 Ubiquitin mediated proteolysis"
			},
			{
				"name":"04122 Sulfur relay system [PATH:scc04122]",
				"children":[
				{
					"name":"Spico_0525 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Spico_0283 tRNA-specific 2-thiouridylase mnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"Spico_0410 Radical SAM domain protein\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				},
				{
					"name":"Spico_0411 Radical SAM domain protein\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				},
				{
					"name":"Spico_0524 tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				}
				]
			},
			{
				"name":"03050 Proteasome"
			},
			{
				"name":"03018 RNA degradation [PATH:scc03018]",
				"children":[
				{
					"name":"Spico_1330 DEAD\/DEAH box helicase domain protein\tK03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]"
				},
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Spico_0599 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"Spico_0305 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Spico_0432 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1234 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"Spico_1689 2,3 cyclic-nucleotide 2-phosphodiesterase\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Spico_0529 poly(A) polymerase\tK00970 pcnB; poly(A) polymerase [EC:2.7.7.19]"
				}
				]
			}
			]
		},
		{
			"name":"09124 Replication and repair",
			"children":[
			{
				"name":"03030 DNA replication [PATH:scc03030]",
				"children":[
				{
					"name":"Spico_0281 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1795 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0635 hypothetical protein\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1840 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1591 DNA polymerase III delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0002 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0697 replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"Spico_0619 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_0730 RNase HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"Spico_0507 Ribonuclease H\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03410 Base excision repair [PATH:scc03410]",
				"children":[
				{
					"name":"Spico_0856 DNA-(apurinic or apyrimidinic site) lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_0843 DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_1824 DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_0977 Uracil-DNA glycosylase superfamily\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
				},
				{
					"name":"Spico_0288 HhH-GPD family protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"Spico_0358 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
				},
				{
					"name":"Spico_1497 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Spico_1452 phage SPO1 DNA polymerase-related protein\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"Spico_0748 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0397 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03420 Nucleotide excision repair [PATH:scc03420]",
				"children":[
				{
					"name":"Spico_0676 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0465 Excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Spico_0943 Excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"Spico_1592 UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"Spico_0744 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1194 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Spico_0685 helicase domain protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03430 Mismatch repair [PATH:scc03430]",
				"children":[
				{
					"name":"Spico_0590 DNA mismatch repair protein mutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Spico_0455 DNA mismatch repair protein MutS domain protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"Spico_0405 DNA mismatch repair protein mutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"Spico_0744 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1194 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1062 Exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
				},
				{
					"name":"Spico_0783 Exodeoxyribonuclease 7 large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"Spico_0784 Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"Spico_0397 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1795 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0002 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0635 hypothetical protein\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1840 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1591 DNA polymerase III delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0281 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Spico_0552 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				}
				]
			},
			{
				"name":"03440 Homologous recombination [PATH:scc03440]",
				"children":[
				{
					"name":"Spico_0397 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_0003 DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"Spico_1841 DNA replication and repair protein RecR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"Spico_0608 RecA protein\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0584 Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"Spico_0585 Holliday junction DNA helicase subunit RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0583 Crossover junction endodeoxyribonuclease ruvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"Spico_0133 putative transcriptional regulator\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1161 putative transcriptional regulator\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1797 ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1795 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0002 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0635 hypothetical protein\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1840 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1591 DNA polymerase III delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0281 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1451 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03450 Non-homologous end-joining"
			},
			{
				"name":"03460 Fanconi anemia pathway"
			}
			]
		},
		{
			"name":"09126 Chromosome",
			"children":[
			{
				"name":"03082 ATP-dependent chromatin remodeling"
			},
			{
				"name":"03083 Polycomb repressive complex"
			}
			]
		},
		{
			"name":"09125 Information processing in viruses",
			"children":[
			{
				"name":"03230 Viral genome structure"
			},
			{
				"name":"03240 Viral replication"
			},
			{
				"name":"03250 Viral life cycle - HIV-1 [PATH:scc03250]",
				"children":[
				{
					"name":"Spico_1861 Peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"03260 Virion - Human immunodeficiency virus"
			},
			{
				"name":"03271 Virion - Rotavirus"
			},
			{
				"name":"03262 Virion - Coronavirus"
			},
			{
				"name":"03261 Virion - Influenza virus"
			},
			{
				"name":"03263 Virion - Enterovirus"
			},
			{
				"name":"03264 Virion - Flavivirus and Alphavirus"
			},
			{
				"name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus"
			},
			{
				"name":"03273 Virion - Lassa virus and SFTS virus"
			},
			{
				"name":"03272 Virion - Hepatitis viruses"
			},
			{
				"name":"03266 Virion - Herpesvirus"
			},
			{
				"name":"03268 Virion - Orthopoxvirus"
			},
			{
				"name":"03267 Virion - Adenovirus"
			},
			{
				"name":"03259 Virion - Bacteriophages T4 and T7"
			},
			{
				"name":"03258 Virion - Bacteriophage lambda"
			}
			]
		}
		]
	},
	{
		"name":"09130 Environmental Information Processing",
		"children":[
		{
			"name":"09131 Membrane transport",
			"children":[
			{
				"name":"02010 ABC transporters [PATH:scc02010]",
				"children":[
				{
					"name":"Spico_0272 extracellular solute-binding protein family 1\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"Spico_0310 extracellular solute-binding protein family 1\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"Spico_0273 binding-protein-dependent transport systems inner membrane component\tK02011 afuB; iron(III) transport system permease protein"
				},
				{
					"name":"Spico_0311 binding-protein-dependent transport systems inner membrane component\tK02011 afuB; iron(III) transport system permease protein"
				},
				{
					"name":"Spico_0274 Polyamine-transporting ATPase\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]"
				},
				{
					"name":"Spico_0312 Polyamine-transporting ATPase\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]"
				},
				{
					"name":"Spico_0940 ABC transporter, periplasmic binding protein, thiB subfamily\tK02064 thiB; thiamine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0941 binding-protein-dependent transport systems inner membrane component\tK02063 thiP; thiamine transport system permease protein"
				},
				{
					"name":"Spico_0942 Fe(3+)-transporting ATPase\tK02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]"
				},
				{
					"name":"Spico_0850 extracellular solute-binding protein family 1\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"Spico_1297 extracellular solute-binding protein family 1\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0849 binding-protein-dependent transport systems inner membrane component\tK11070 potC; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"Spico_0848 binding-protein-dependent transport systems inner membrane component\tK11071 potB; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"Spico_0847 spermidine\/putrescine ABC transporter ATPase subunit\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]"
				},
				{
					"name":"Spico_0269 carbohydrate ABC transporter ATP-binding protein, CUT1 family\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_0259 extracellular solute-binding protein family 1\tK10117 msmE; raffinose\/stachyose\/melibiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0893 extracellular solute-binding protein family 1\tK10117 msmE; raffinose\/stachyose\/melibiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0260 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK10118 msmF; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0895 binding-protein-dependent transport systems inner membrane component\tK10118 msmF; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0261 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10119 msmG; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0894 binding-protein-dependent transport systems inner membrane component\tK10119 msmG; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_1210 extracellular solute-binding protein family 1\tK10192 togB; oligogalacturonide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1209 binding-protein-dependent transport systems inner membrane component\tK10193 togM; oligogalacturonide transport system permease protein"
				},
				{
					"name":"Spico_1208 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10194 togN; oligogalacturonide transport system permease protein"
				},
				{
					"name":"Spico_1279 extracellular solute-binding protein family 1\tK17241 aguE; alpha-1,4-digalacturonate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1280 binding-protein-dependent transport systems inner membrane component\tK17242 aguF; alpha-1,4-digalacturonate transport system permease protein"
				},
				{
					"name":"Spico_1281 binding-protein-dependent transport systems inner membrane component\tK17243 aguG; alpha-1,4-digalacturonate transport system permease protein"
				},
				{
					"name":"Spico_0058 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0362 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0385 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0500 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0714 sugar ABC transporter substrate-binding protein\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1072 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1532 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0056 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0364 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0383 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0494 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0716 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1071 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1534 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0057 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0363 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0382 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0493 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0715 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1070 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1533 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0723 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK10240 cebE; cellobiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0722 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK10241 cebF; cellobiose transport system permease protein"
				},
				{
					"name":"Spico_0721 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10242 cebG; cellobiose transport system permease protein"
				},
				{
					"name":"Spico_0062 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"Spico_1112 basic membrane lipoprotein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"Spico_0064 nucleoside ABC transporter membrane protein\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_1110 inner-membrane translocator\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_0065 nucleoside ABC transporter membrane protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_1109 nucleoside ABC transporter membrane protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_0063 nucleoside ABC transporter ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"Spico_1111 nucleoside ABC transporter ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"Spico_0014 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0078 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0097 bifunctional carbohydrate binding and transport protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1403 hypothetical protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1629 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1644 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1814 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0016 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0079 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0099 inner-membrane translocator\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0100 inner-membrane translocator\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1628 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1645 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1812 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0015 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0081 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0098 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1626 monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1627 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1646 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1813 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0335 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK23508 ytfQ; galactofuranose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0337 monosaccharide ABC transporter membrane protein, CUT2 family\tK23509 ytfT; galactofuranose transport system permease protein"
				},
				{
					"name":"Spico_0338 monosaccharide ABC transporter membrane protein, CUT2 family\tK23509 ytfT; galactofuranose transport system permease protein"
				},
				{
					"name":"Spico_0336 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]"
				},
				{
					"name":"Spico_1400 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				},
				{
					"name":"Spico_1404 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				},
				{
					"name":"Spico_1398 monosaccharide ABC transporter membrane protein, CUT2 family\tK10541 mglC; methyl-galactoside transport system permease protein"
				},
				{
					"name":"Spico_1399 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10542 mglA; methyl-galactoside transport system ATP-binding protein [EC:7.5.2.11]"
				},
				{
					"name":"Spico_1659 rhamnose-binding protein\tK10559 rhaS; rhamnose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1657 inner-membrane translocator\tK10560 rhaP; rhamnose transport system permease protein"
				},
				{
					"name":"Spico_1656 inner-membrane translocator\tK10561 rhaQ; rhamnose transport system permease protein"
				},
				{
					"name":"Spico_1658 Monosaccharide-transporting ATPase\tK10562 rhaT; rhamnose transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_1039 sugar ABC transporter (sugar-binding protein)\tK17213 K17213; inositol transport system substrate-binding protein"
				},
				{
					"name":"Spico_1037 inner-membrane translocator\tK17214 K17214; inositol transport system permease protein"
				},
				{
					"name":"Spico_1038 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK17215 K17215; inositol transport system ATP-binding protein"
				},
				{
					"name":"Spico_1415 extracellular solute-binding protein family 1\tK05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1413 binding-protein-dependent transport systems inner membrane component\tK05814 ugpA; sn-glycerol 3-phosphate transport system permease protein"
				},
				{
					"name":"Spico_1414 binding-protein-dependent transport systems inner membrane component\tK05815 ugpE; sn-glycerol 3-phosphate transport system permease protein"
				},
				{
					"name":"Spico_0435 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0436 phosphate ABC transporter membrane protein 1, PhoT family\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Spico_0437 phosphate ABC transporter, inner membrane subunit PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Spico_0438 phosphate ABC transporter ATP-binding protein, PhoT family\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Spico_1408 amino acid ABC transporter substrate-binding protein, PAAT family\tK10039 peb1A; aspartate\/glutamate\/glutamine transport system substrate-binding protein"
				},
				{
					"name":"Spico_1406 amino acid ABC transporter membrane protein 2, PAAT family\tK10040 peb1B; aspartate\/glutamate\/glutamine transport system permease protein"
				},
				{
					"name":"Spico_1407 amino acid ABC transporter membrane protein 1, PAAT family\tK10040 peb1B; aspartate\/glutamate\/glutamine transport system permease protein"
				},
				{
					"name":"Spico_1409 amino acid ABC transporter ATP-binding protein, PAAT family\tK10041 peb1C; aspartate\/glutamate\/glutamine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"Spico_0107 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0879 amino acid\/amide ABC transporter substrate-binding protein, HAAT family\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1092 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1580 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0108 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0880 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1091 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1579 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0109 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0881 amino acid\/amide ABC transporter membrane protein 2, HAAT family\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1090 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1578 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0110 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0882 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1089 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1577 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0111 ABC transporter related protein\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0883 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1088 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1576 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0227 NLPA lipoprotein\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0226 binding-protein-dependent transport systems inner membrane component\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"Spico_0225 Sulfate-transporting ATPase\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"Spico_1201 extracellular solute-binding protein family 5\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1196 binding-protein-dependent transport systems inner membrane component\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1197 binding-protein-dependent transport systems inner membrane component\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1198 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1199 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1668 periplasmic solute binding protein\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"Spico_0223 ABC-3 protein\tK09816 znuB; zinc transport system permease protein"
				},
				{
					"name":"Spico_0224 Fe(3+)-transporting ATPase\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]"
				},
				{
					"name":"Spico_1007 BioY protein\tK03523 bioY; biotin transport system substrate-specific component"
				},
				{
					"name":"Spico_1114 cobalt transport protein\tK16783 bioN; biotin transport system permease protein"
				},
				{
					"name":"Spico_1113 Fe(3+)-transporting ATPase\tK16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Spico_1326 cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"Spico_1394 cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"Spico_0540 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Spico_0542 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Spico_0541 Phosphonate-transporting ATPase\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Spico_0601 permease YjgP\/YjgQ family protein\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Spico_0602 permease YjgP\/YjgQ family protein\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Spico_1585 Fe(3+)-transporting ATPase\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Spico_1536 Xenobiotic-transporting ATPase\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1535 Xenobiotic-transporting ATPase\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_0172 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1273 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1521 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_0171 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1272 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1520 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				}
				]
			},
			{
				"name":"02060 Phosphotransferase system (PTS) [PATH:scc02060]",
				"children":[
				{
					"name":"Spico_1508 phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"Spico_1685 phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"Spico_1509 Phosphotransferase system, phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"Spico_1589 Phosphotransferase system, phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"Spico_0753 putative PTS IIA-like nitrogen-regulatory protein PtsN\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"Spico_1116 putative PTS IIA-like nitrogen-regulatory protein PtsN\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]"
				}
				]
			},
			{
				"name":"03070 Bacterial secretion system [PATH:scc03070]",
				"children":[
				{
					"name":"Spico_0214 protein-export membrane protein SecD\tK03072 secD; preprotein translocase subunit SecD"
				},
				{
					"name":"Spico_1728 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Spico_0474 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Spico_1696 protein translocase subunit secY\/sec61 alpha\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Spico_0213 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Spico_0007 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Spico_0639 protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Spico_0539 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Spico_0509 signal recognition particle subunit FFH\/SRP54 (srp54)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				}
				]
			}
			]
		},
		{
			"name":"09132 Signal transduction",
			"children":[
			{
				"name":"02020 Two-component system [PATH:scc02020]",
				"children":[
				{
					"name":"Spico_0393 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0421 multi-sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0422 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Spico_0435 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0001 chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Spico_1745 citrate lyase ligase\tK01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]"
				},
				{
					"name":"Spico_1750 Citrate lyase acyl carrier protein\tK01646 citD; citrate lyase subunit gamma (acyl carrier protein)"
				},
				{
					"name":"Spico_1749 Citryl-CoA lyase\tK01644 citE; citrate lyase subunit beta \/ citryl-CoA lyase [EC:4.1.3.34]"
				},
				{
					"name":"Spico_1748 citrate lyase, alpha subunit\tK01643 citF; citrate lyase subunit alpha \/ citrate CoA-transferase [EC:2.8.3.10]"
				},
				{
					"name":"Spico_1744 holo-ACP synthase CitX\tK13927 citXG; holo-ACP synthase \/ triphosphoribosyl-dephospho-CoA synthase [EC:2.7.7.61 2.4.2.52]"
				},
				{
					"name":"Spico_1680 Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_1352 two component, sigma54 specific, transcriptional regulator, Fis family\tK07714 atoC; two-component system, NtrC family, response regulator AtoC"
				},
				{
					"name":"Spico_1586 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"Spico_1317 putative transcriptional regulator, Crp\/Fnr family\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Spico_0178 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1382 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1402 multi-sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1740 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0177 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1206 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1381 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1401 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1624 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1741 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_0157 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				}
				]
			},
			{
				"name":"04010 MAPK signaling pathway"
			},
			{
				"name":"04013 MAPK signaling pathway - fly"
			},
			{
				"name":"04016 MAPK signaling pathway - plant"
			},
			{
				"name":"04011 MAPK signaling pathway - yeast"
			},
			{
				"name":"04012 ErbB signaling pathway"
			},
			{
				"name":"04014 Ras signaling pathway"
			},
			{
				"name":"04015 Rap1 signaling pathway"
			},
			{
				"name":"04310 Wnt signaling pathway"
			},
			{
				"name":"04330 Notch signaling pathway"
			},
			{
				"name":"04340 Hedgehog signaling pathway"
			},
			{
				"name":"04341 Hedgehog signaling pathway - fly"
			},
			{
				"name":"04350 TGF-beta signaling pathway"
			},
			{
				"name":"04390 Hippo signaling pathway"
			},
			{
				"name":"04391 Hippo signaling pathway - fly"
			},
			{
				"name":"04392 Hippo signaling pathway - multiple species"
			},
			{
				"name":"04370 VEGF signaling pathway"
			},
			{
				"name":"04371 Apelin signaling pathway"
			},
			{
				"name":"04630 JAK-STAT signaling pathway"
			},
			{
				"name":"04064 NF-kappa B signaling pathway"
			},
			{
				"name":"04668 TNF signaling pathway"
			},
			{
				"name":"04066 HIF-1 signaling pathway"
			},
			{
				"name":"04068 FoxO signaling pathway"
			},
			{
				"name":"04020 Calcium signaling pathway"
			},
			{
				"name":"04070 Phosphatidylinositol signaling system"
			},
			{
				"name":"04072 Phospholipase D signaling pathway"
			},
			{
				"name":"04071 Sphingolipid signaling pathway"
			},
			{
				"name":"04024 cAMP signaling pathway"
			},
			{
				"name":"04022 cGMP-PKG signaling pathway"
			},
			{
				"name":"04151 PI3K-Akt signaling pathway"
			},
			{
				"name":"04152 AMPK signaling pathway"
			},
			{
				"name":"04150 mTOR signaling pathway"
			},
			{
				"name":"04075 Plant hormone signal transduction"
			}
			]
		},
		{
			"name":"09133 Signaling molecules and interaction",
			"children":[
			{
				"name":"04080 Neuroactive ligand-receptor interaction"
			},
			{
				"name":"04082 Neuroactive ligand signaling"
			},
			{
				"name":"04081 Hormone signaling"
			},
			{
				"name":"04060 Cytokine-cytokine receptor interaction"
			},
			{
				"name":"04061 Viral protein interaction with cytokine and cytokine receptor"
			},
			{
				"name":"04512 ECM-receptor interaction"
			},
			{
				"name":"04514 Cell adhesion molecule (CAM) interaction"
			},
			{
				"name":"04517 IgSF CAM signaling"
			},
			{
				"name":"04518 Integrin signaling"
			},
			{
				"name":"04519 Cadherin signaling"
			}
			]
		}
		]
	},
	{
		"name":"09140 Cellular Processes",
		"children":[
		{
			"name":"09141 Transport and catabolism",
			"children":[
			{
				"name":"04144 Endocytosis"
			},
			{
				"name":"04145 Phagocytosis",
				"children":[
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				}
				]
			},
			{
				"name":"04142 Lysosome biogenesis [PATH:scc04142]",
				"children":[
				{
					"name":"Spico_0384 Galactosylceramidase\tK01202 GALC; galactosylceramidase [EC:3.2.1.46]"
				},
				{
					"name":"Spico_0365 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Spico_0897 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Spico_0890 Beta-mannosidase\tK01192 E3.2.1.25; beta-mannosidase [EC:3.2.1.25]"
				}
				]
			},
			{
				"name":"04146 Peroxisome [PATH:scc04146]",
				"children":[
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0266 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Spico_1752 Manganese\/iron superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]"
				}
				]
			},
			{
				"name":"04149 Peroxisome - yeast"
			},
			{
				"name":"04140 Autophagy - animal"
			},
			{
				"name":"04138 Autophagy - yeast"
			},
			{
				"name":"04136 Autophagy - other"
			},
			{
				"name":"04137 Mitophagy - animal"
			},
			{
				"name":"04139 Mitophagy - yeast"
			},
			{
				"name":"04148 Efferocytosis"
			}
			]
		},
		{
			"name":"09143 Cell growth and death",
			"children":[
			{
				"name":"04110 Cell cycle"
			},
			{
				"name":"04111 Cell cycle - yeast"
			},
			{
				"name":"04112 Cell cycle - Caulobacter"
			},
			{
				"name":"04113 Meiosis - yeast"
			},
			{
				"name":"04114 Oocyte meiosis"
			},
			{
				"name":"04210 Apoptosis"
			},
			{
				"name":"04214 Apoptosis - fly"
			},
			{
				"name":"04215 Apoptosis - multiple species"
			},
			{
				"name":"04216 Ferroptosis"
			},
			{
				"name":"04217 Necroptosis"
			},
			{
				"name":"04115 p53 signaling pathway"
			},
			{
				"name":"04218 Cellular senescence"
			},
			{
				"name":"04156 Integrated stress response (ISR) signaling pathway [PATH:scc04156]",
				"children":[
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Spico_R0012 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0046 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0051 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				}
				]
			}
			]
		},
		{
			"name":"09144 Cellular community - eukaryotes",
			"children":[
			{
				"name":"04510 Focal adhesion"
			},
			{
				"name":"04520 Adherens junction"
			},
			{
				"name":"04530 Tight junction"
			},
			{
				"name":"04540 Gap junction"
			},
			{
				"name":"04550 Signaling pathways regulating pluripotency of stem cells"
			}
			]
		},
		{
			"name":"09145 Cellular community - prokaryotes",
			"children":[
			{
				"name":"02024 Quorum sensing [PATH:scc02024]",
				"children":[
				{
					"name":"Spico_1410 quorum-sensing autoinducer 2 (AI-2), LuxS\tK07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]"
				},
				{
					"name":"Spico_0877 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase\tK01626 E2.5.1.54; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]"
				},
				{
					"name":"Spico_0107 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0879 amino acid\/amide ABC transporter substrate-binding protein, HAAT family\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1092 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1580 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0108 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0880 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1091 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1579 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0109 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0881 amino acid\/amide ABC transporter membrane protein 2, HAAT family\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1090 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1578 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0110 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0882 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1089 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1577 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0111 ABC transporter related protein\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0883 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1088 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1576 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_1317 putative transcriptional regulator, Crp\/Fnr family\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Spico_0289 protein of unknown function DUF606\tK09936 TC.BAT2; bacterial\/archaeal transporter family-2 protein"
				},
				{
					"name":"Spico_1201 extracellular solute-binding protein family 5\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1196 binding-protein-dependent transport systems inner membrane component\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1197 binding-protein-dependent transport systems inner membrane component\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1198 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1199 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1596 extracellular solute-binding protein family 5\tK02035 ABC.PE.S; peptide\/nickel transport system substrate-binding protein"
				},
				{
					"name":"Spico_0007 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Spico_1728 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Spico_0474 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Spico_1696 protein translocase subunit secY\/sec61 alpha\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Spico_0213 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Spico_0639 protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Spico_0539 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Spico_0509 signal recognition particle subunit FFH\/SRP54 (srp54)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				}
				]
			},
			{
				"name":"05111 Biofilm formation - Vibrio cholerae"
			},
			{
				"name":"02025 Biofilm formation - Pseudomonas aeruginosa"
			},
			{
				"name":"02026 Biofilm formation - Escherichia coli"
			}
			]
		},
		{
			"name":"09142 Cell motility",
			"children":[
			{
				"name":"02030 Bacterial chemotaxis [PATH:scc02030]",
				"children":[
				{
					"name":"Spico_0014 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0078 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0097 bifunctional carbohydrate binding and transport protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1403 hypothetical protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1629 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1644 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1814 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1400 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				},
				{
					"name":"Spico_1404 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				}
				]
			},
			{
				"name":"02040 Flagellar assembly [PATH:scc02040]",
				"children":[
				{
					"name":"Spico_0618 RNA polymerase, sigma 70 subunit, RpoD\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Spico_0629 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Spico_1586 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				}
				]
			},
			{
				"name":"04814 Motor proteins"
			},
			{
				"name":"04820 Cytoskeleton in muscle cells",
				"children":[
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				}
				]
			},
			{
				"name":"04810 Regulation of actin cytoskeleton"
			}
			]
		}
		]
	},
	{
		"name":"09150 Organismal Systems",
		"children":[
		{
			"name":"09151 Immune system",
			"children":[
			{
				"name":"04640 Hematopoietic cell lineage"
			},
			{
				"name":"04610 Complement and coagulation cascades"
			},
			{
				"name":"04611 Platelet activation"
			},
			{
				"name":"04613 Neutrophil extracellular trap formation"
			},
			{
				"name":"04620 Toll-like receptor signaling pathway"
			},
			{
				"name":"04624 Toll and Imd signaling pathway"
			},
			{
				"name":"04621 NOD-like receptor signaling pathway"
			},
			{
				"name":"04622 RIG-I-like receptor signaling pathway"
			},
			{
				"name":"04623 Cytosolic DNA-sensing pathway"
			},
			{
				"name":"04625 C-type lectin receptor signaling pathway"
			},
			{
				"name":"04650 Natural killer cell mediated cytotoxicity"
			},
			{
				"name":"04612 Antigen processing and presentation"
			},
			{
				"name":"04660 T cell receptor signaling pathway"
			},
			{
				"name":"04658 Th1 and Th2 cell differentiation"
			},
			{
				"name":"04659 Th17 cell differentiation"
			},
			{
				"name":"04657 IL-17 signaling pathway"
			},
			{
				"name":"04662 B cell receptor signaling pathway"
			},
			{
				"name":"04664 Fc epsilon RI signaling pathway"
			},
			{
				"name":"04666 Fc gamma R-mediated phagosome formation"
			},
			{
				"name":"04670 Leukocyte transendothelial migration"
			},
			{
				"name":"04672 Intestinal immune network for IgA production"
			},
			{
				"name":"04062 Chemokine signaling pathway"
			}
			]
		},
		{
			"name":"09152 Endocrine system",
			"children":[
			{
				"name":"04911 Insulin secretion"
			},
			{
				"name":"04910 Insulin signaling pathway"
			},
			{
				"name":"04922 Glucagon signaling pathway"
			},
			{
				"name":"04923 Regulation of lipolysis in adipocytes"
			},
			{
				"name":"04920 Adipocytokine signaling pathway"
			},
			{
				"name":"03320 PPAR signaling pathway"
			},
			{
				"name":"04929 GnRH secretion"
			},
			{
				"name":"04912 GnRH signaling pathway"
			},
			{
				"name":"04913 Ovarian steroidogenesis"
			},
			{
				"name":"04915 Estrogen signaling pathway"
			},
			{
				"name":"04914 Progesterone-mediated oocyte maturation"
			},
			{
				"name":"04917 Prolactin signaling pathway"
			},
			{
				"name":"04921 Oxytocin signaling pathway"
			},
			{
				"name":"04926 Relaxin signaling pathway"
			},
			{
				"name":"04935 Growth hormone synthesis, secretion and action"
			},
			{
				"name":"04918 Thyroid hormone synthesis"
			},
			{
				"name":"04919 Thyroid hormone signaling pathway"
			},
			{
				"name":"04928 Parathyroid hormone synthesis, secretion and action"
			},
			{
				"name":"04916 Melanogenesis"
			},
			{
				"name":"04924 Renin secretion"
			},
			{
				"name":"04614 Renin-angiotensin system"
			},
			{
				"name":"04925 Aldosterone synthesis and secretion"
			},
			{
				"name":"04927 Cortisol synthesis and secretion"
			}
			]
		},
		{
			"name":"09153 Circulatory system",
			"children":[
			{
				"name":"04260 Cardiac muscle contraction"
			},
			{
				"name":"04261 Adrenergic signaling in cardiomyocytes"
			},
			{
				"name":"04270 Vascular smooth muscle contraction"
			}
			]
		},
		{
			"name":"09154 Digestive system",
			"children":[
			{
				"name":"04970 Salivary secretion"
			},
			{
				"name":"04971 Gastric acid secretion"
			},
			{
				"name":"04972 Pancreatic secretion"
			},
			{
				"name":"04976 Bile secretion"
			},
			{
				"name":"04973 Carbohydrate digestion and absorption"
			},
			{
				"name":"04974 Protein digestion and absorption"
			},
			{
				"name":"04975 Fat digestion and absorption"
			},
			{
				"name":"04979 Cholesterol metabolism"
			},
			{
				"name":"04977 Vitamin digestion and absorption"
			},
			{
				"name":"04981 Folate transport and metabolism [PATH:scc04981]",
				"children":[
				{
					"name":"Spico_1115 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"Spico_1082 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				}
				]
			},
			{
				"name":"04980 Cobalamin transport and metabolism"
			},
			{
				"name":"04978 Mineral absorption"
			}
			]
		},
		{
			"name":"09155 Excretory system",
			"children":[
			{
				"name":"04962 Vasopressin-regulated water reabsorption"
			},
			{
				"name":"04960 Aldosterone-regulated sodium reabsorption"
			},
			{
				"name":"04961 Endocrine and other factor-regulated calcium reabsorption"
			},
			{
				"name":"04964 Proximal tubule bicarbonate reclamation"
			},
			{
				"name":"04966 Collecting duct acid secretion"
			}
			]
		},
		{
			"name":"09156 Nervous system",
			"children":[
			{
				"name":"04724 Glutamatergic synapse"
			},
			{
				"name":"04727 GABAergic synapse"
			},
			{
				"name":"04725 Cholinergic synapse"
			},
			{
				"name":"04728 Dopaminergic synapse"
			},
			{
				"name":"04726 Serotonergic synapse"
			},
			{
				"name":"04720 Long-term potentiation"
			},
			{
				"name":"04730 Long-term depression"
			},
			{
				"name":"04723 Retrograde endocannabinoid signaling"
			},
			{
				"name":"04721 Synaptic vesicle cycle"
			},
			{
				"name":"04722 Neurotrophin signaling pathway"
			}
			]
		},
		{
			"name":"09157 Sensory system",
			"children":[
			{
				"name":"04744 Phototransduction"
			},
			{
				"name":"04745 Phototransduction - fly"
			},
			{
				"name":"04740 Olfactory transduction"
			},
			{
				"name":"04742 Taste transduction"
			},
			{
				"name":"04750 Inflammatory mediator regulation of TRP channels"
			}
			]
		},
		{
			"name":"09158 Development and regeneration",
			"children":[
			{
				"name":"04320 Dorso-ventral axis formation"
			},
			{
				"name":"04360 Axon guidance"
			},
			{
				"name":"04361 Axon regeneration"
			},
			{
				"name":"04380 Osteoclast differentiation"
			},
			{
				"name":"04382 Cornified envelope formation",
				"children":[
				{
					"name":"Spico_0441 serine palmitoyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				}
				]
			}
			]
		},
		{
			"name":"09149 Aging",
			"children":[
			{
				"name":"04211 Longevity regulating pathway"
			},
			{
				"name":"04212 Longevity regulating pathway - worm"
			},
			{
				"name":"04213 Longevity regulating pathway - multiple species"
			}
			]
		},
		{
			"name":"09159 Environmental adaptation",
			"children":[
			{
				"name":"04710 Circadian rhythm"
			},
			{
				"name":"04713 Circadian entrainment"
			},
			{
				"name":"04711 Circadian rhythm - fly"
			},
			{
				"name":"04712 Circadian rhythm - plant"
			},
			{
				"name":"04714 Thermogenesis"
			},
			{
				"name":"04626 Plant-pathogen interaction"
			}
			]
		}
		]
	},
	{
		"name":"09160 Human Diseases",
		"children":[
		{
			"name":"09161 Cancer: overview",
			"children":[
			{
				"name":"05200 Pathways in cancer"
			},
			{
				"name":"05202 Transcriptional misregulation in cancer"
			},
			{
				"name":"05206 MicroRNAs in cancer"
			},
			{
				"name":"05205 Proteoglycans in cancer"
			},
			{
				"name":"05204 Chemical carcinogenesis - DNA adducts"
			},
			{
				"name":"05207 Chemical carcinogenesis - receptor activation"
			},
			{
				"name":"05208 Chemical carcinogenesis - reactive oxygen species"
			},
			{
				"name":"05203 Viral carcinogenesis"
			},
			{
				"name":"05230 Central carbon metabolism in cancer"
			},
			{
				"name":"05231 Choline metabolism in cancer"
			},
			{
				"name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer"
			}
			]
		},
		{
			"name":"09162 Cancer: specific types",
			"children":[
			{
				"name":"05210 Colorectal cancer"
			},
			{
				"name":"05212 Pancreatic cancer"
			},
			{
				"name":"05225 Hepatocellular carcinoma"
			},
			{
				"name":"05226 Gastric cancer"
			},
			{
				"name":"05214 Glioma"
			},
			{
				"name":"05216 Thyroid cancer"
			},
			{
				"name":"05221 Acute myeloid leukemia"
			},
			{
				"name":"05220 Chronic myeloid leukemia"
			},
			{
				"name":"05217 Basal cell carcinoma"
			},
			{
				"name":"05218 Melanoma"
			},
			{
				"name":"05211 Renal cell carcinoma"
			},
			{
				"name":"05219 Bladder cancer"
			},
			{
				"name":"05215 Prostate cancer"
			},
			{
				"name":"05213 Endometrial cancer"
			},
			{
				"name":"05224 Breast cancer"
			},
			{
				"name":"05222 Small cell lung cancer"
			},
			{
				"name":"05223 Non-small cell lung cancer"
			}
			]
		},
		{
			"name":"09172 Infectious disease: viral",
			"children":[
			{
				"name":"05166 Human T-cell leukemia virus 1 infection"
			},
			{
				"name":"05170 Human immunodeficiency virus 1 infection"
			},
			{
				"name":"05161 Hepatitis B"
			},
			{
				"name":"05160 Hepatitis C"
			},
			{
				"name":"05171 Coronavirus disease"
			},
			{
				"name":"05164 Influenza A"
			},
			{
				"name":"05162 Measles"
			},
			{
				"name":"05168 Herpes simplex virus 1 infection"
			},
			{
				"name":"05163 Human cytomegalovirus infection"
			},
			{
				"name":"05167 Kaposi sarcoma-associated herpesvirus infection"
			},
			{
				"name":"05169 Epstein-Barr virus infection"
			},
			{
				"name":"05165 Human papillomavirus infection"
			}
			]
		},
		{
			"name":"09171 Infectious disease: bacterial",
			"children":[
			{
				"name":"05110 Vibrio cholerae infection"
			},
			{
				"name":"05120 Epithelial cell signaling in Helicobacter pylori infection"
			},
			{
				"name":"05130 Pathogenic Escherichia coli infection"
			},
			{
				"name":"05132 Salmonella infection"
			},
			{
				"name":"05131 Shigellosis"
			},
			{
				"name":"05135 Yersinia infection"
			},
			{
				"name":"05133 Pertussis"
			},
			{
				"name":"05134 Legionellosis"
			},
			{
				"name":"05150 Staphylococcus aureus infection"
			},
			{
				"name":"05152 Tuberculosis"
			},
			{
				"name":"05100 Bacterial invasion of epithelial cells"
			}
			]
		},
		{
			"name":"09174 Infectious disease: parasitic",
			"children":[
			{
				"name":"05146 Amoebiasis"
			},
			{
				"name":"05144 Malaria"
			},
			{
				"name":"05145 Toxoplasmosis"
			},
			{
				"name":"05140 Leishmaniasis"
			},
			{
				"name":"05142 Chagas disease"
			},
			{
				"name":"05143 African trypanosomiasis"
			}
			]
		},
		{
			"name":"09163 Immune disease",
			"children":[
			{
				"name":"05310 Asthma"
			},
			{
				"name":"05322 Systemic lupus erythematosus"
			},
			{
				"name":"05323 Rheumatoid arthritis"
			},
			{
				"name":"05320 Autoimmune thyroid disease"
			},
			{
				"name":"05321 Inflammatory bowel disease"
			},
			{
				"name":"05330 Allograft rejection"
			},
			{
				"name":"05332 Graft-versus-host disease"
			},
			{
				"name":"05340 Primary immunodeficiency"
			}
			]
		},
		{
			"name":"09164 Neurodegenerative disease",
			"children":[
			{
				"name":"05010 Alzheimer disease"
			},
			{
				"name":"05012 Parkinson disease"
			},
			{
				"name":"05014 Amyotrophic lateral sclerosis"
			},
			{
				"name":"05016 Huntington disease"
			},
			{
				"name":"05017 Spinocerebellar ataxia"
			},
			{
				"name":"05020 Prion disease"
			},
			{
				"name":"05022 Pathways of neurodegeneration - multiple diseases"
			}
			]
		},
		{
			"name":"09165 Substance dependence",
			"children":[
			{
				"name":"05030 Cocaine addiction"
			},
			{
				"name":"05031 Amphetamine addiction"
			},
			{
				"name":"05032 Morphine addiction"
			},
			{
				"name":"05033 Nicotine addiction"
			},
			{
				"name":"05034 Alcoholism"
			}
			]
		},
		{
			"name":"09166 Cardiovascular disease",
			"children":[
			{
				"name":"05417 Lipid and atherosclerosis"
			},
			{
				"name":"05418 Fluid shear stress and atherosclerosis"
			},
			{
				"name":"05410 Hypertrophic cardiomyopathy"
			},
			{
				"name":"05412 Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"05414 Dilated cardiomyopathy"
			},
			{
				"name":"05415 Diabetic cardiomyopathy"
			},
			{
				"name":"05416 Viral myocarditis"
			}
			]
		},
		{
			"name":"09167 Endocrine and metabolic disease",
			"children":[
			{
				"name":"04930 Type II diabetes mellitus"
			},
			{
				"name":"04940 Type I diabetes mellitus"
			},
			{
				"name":"04950 Maturity onset diabetes of the young"
			},
			{
				"name":"04936 Alcoholic liver disease"
			},
			{
				"name":"04932 Non-alcoholic fatty liver disease"
			},
			{
				"name":"04931 Insulin resistance"
			},
			{
				"name":"04933 AGE-RAGE signaling pathway in diabetic complications"
			},
			{
				"name":"04934 Cushing syndrome"
			}
			]
		},
		{
			"name":"09175 Drug resistance: antimicrobial",
			"children":[
			{
				"name":"01501 beta-Lactam resistance [PATH:scc01501]",
				"children":[
				{
					"name":"Spico_1201 extracellular solute-binding protein family 5\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1196 binding-protein-dependent transport systems inner membrane component\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1197 binding-protein-dependent transport systems inner membrane component\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1198 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1199 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_0641 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				}
				]
			},
			{
				"name":"01502 Vancomycin resistance [PATH:scc01502]",
				"children":[
				{
					"name":"Spico_0911 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Spico_0653 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"Spico_0652 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Spico_0638 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				}
				]
			},
			{
				"name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:scc01503]",
				"children":[
				{
					"name":"Spico_0917 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Spico_1861 Peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"09176 Drug resistance: antineoplastic",
			"children":[
			{
				"name":"01521 EGFR tyrosine kinase inhibitor resistance"
			},
			{
				"name":"01524 Platinum drug resistance"
			},
			{
				"name":"01523 Antifolate resistance"
			},
			{
				"name":"01522 Endocrine resistance"
			}
			]
		}
		]
	},
	{
		"name":"09180 Brite Hierarchies",
		"children":[
		{
			"name":"09181 Protein families: metabolism",
			"children":[
			{
				"name":"01000 Enzymes [BR:scc01000]"
			},
			{
				"name":"01001 Protein kinases [BR:scc01001]",
				"children":[
				{
					"name":"Spico_0393 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0421 multi-sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0178 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1382 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1402 multi-sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1740 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"01009 Protein phosphatases and associated proteins [BR:scc01009]",
				"children":[
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"01002 Peptidases and inhibitors [BR:scc01002]",
				"children":[
				{
					"name":"Spico_0148 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"Spico_0458 pyroglutamyl-peptidase I\tK01304 PGPEP1; pyroglutamyl-peptidase [EC:3.4.19.3]"
				},
				{
					"name":"Spico_1324 GMP synthase (glutamine-hydrolyzing)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"Spico_0862 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"Spico_0573 glutamate synthase (NADH) large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Spico_1769 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"Spico_0876 DJ-1 family protein\tK03152 thiJ; protein deglycase [EC:3.5.1.124]"
				},
				{
					"name":"Spico_1436 Abortive infection protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"Spico_0798 oligopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
				},
				{
					"name":"Spico_1351 peptidase M3A and M3B thimet\/oligopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
				},
				{
					"name":"Spico_1457 peptidase M16 domain protein\tK06972 PITRM1; presequence protease [EC:3.4.24.-]"
				},
				{
					"name":"Spico_1179 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Spico_0236 Gly-Xaa carboxypeptidase\tK13049 PM20D1; carboxypeptidase PM20D1 [EC:3.4.17.-]"
				},
				{
					"name":"Spico_1461 peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
				},
				{
					"name":"Spico_1851 aminoacyl-histidine dipeptidase\tK01270 pepD; dipeptidase D [EC:3.4.13.-]"
				},
				{
					"name":"Spico_0489 amidohydrolase\tK12941 abgB; aminobenzoyl-glutamate utilization protein B"
				},
				{
					"name":"Spico_0479 methionine aminopeptidase, type I\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"Spico_1833 peptidase M24\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
				},
				{
					"name":"Spico_0621 peptidase M29 aminopeptidase II\tK19689 ampS; aminopeptidase [EC:3.4.11.-]"
				},
				{
					"name":"Spico_0622 peptidase M29 aminopeptidase II\tK19689 ampS; aminopeptidase [EC:3.4.11.-]"
				},
				{
					"name":"Spico_0786 peptidase M29 aminopeptidase II\tK19689 ampS; aminopeptidase [EC:3.4.11.-]"
				},
				{
					"name":"Spico_0220 Carboxypeptidase Taq\tK01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]"
				},
				{
					"name":"Spico_0970 membrane protease FtsH catalytic subunit\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
				},
				{
					"name":"Spico_0696 peptidase M50\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
				},
				{
					"name":"Spico_0793 ATP-dependent Clp protease proteolytic subunit ClpP\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"Spico_1476 ATP-dependent Clp protease proteolytic subunit ClpP\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"Spico_0390 ATP dependent PIM1 peptidase\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]"
				},
				{
					"name":"Spico_1590 SOS-response transcriptional repressor, LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"Spico_0580 signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"Spico_1835 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"Spico_0116 Peptidase S54, rhomboid domain protein\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
				},
				{
					"name":"Spico_0644 ATP-dependent protease hslV\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]"
				},
				{
					"name":"Spico_0389 peptidase U32\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
				},
				{
					"name":"Spico_1318 peptidase U32\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
				},
				{
					"name":"Spico_0707 HflC protein\tK04087 hflC; modulator of FtsH protease HflC"
				},
				{
					"name":"Spico_0706 protease FtsH subunit HflK\tK04088 hflK; modulator of FtsH protease HflK"
				}
				]
			},
			{
				"name":"01003 Glycosyltransferases [BR:scc01003]",
				"children":[
				{
					"name":"Spico_0304 glycosyl transferase group 1\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				},
				{
					"name":"Spico_0935 Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Spico_0651 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				}
				]
			},
			{
				"name":"01005 Lipopolysaccharide biosynthesis proteins [BR:scc01005]",
				"children":[
				{
					"name":"Spico_1623 sugar isomerase (SIS)\tK03271 gmhA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]"
				}
				]
			},
			{
				"name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:scc01011]",
				"children":[
				{
					"name":"Spico_0027 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Spico_0378 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Spico_0908 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"Spico_0703 UDP-N-acetylmuramoylalanine\/D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Spico_0910 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-d iaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Spico_0911 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Spico_0652 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Spico_0638 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"Spico_0604 integral membrane protein MviN\tK03980 murJ; putative peptidoglycan lipid II flippase"
				},
				{
					"name":"Spico_0641 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Spico_0651 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Spico_0295 aminodeoxychorismate lyase\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
				},
				{
					"name":"Spico_1490 rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
				},
				{
					"name":"Spico_0917 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				}
				]
			},
			{
				"name":"01004 Lipid biosynthesis proteins [BR:scc01004]",
				"children":[
				{
					"name":"Spico_1562 (Acyl-carrier-protein) S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Spico_1560 3-oxoacyl-(acyl-carrier-protein) synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Spico_1561 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1573 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Spico_1559 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA\/FabZ\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"Spico_1558 reductase\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"Spico_1567 Butyrate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0433 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1328 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Spico_1853 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				}
				]
			},
			{
				"name":"01008 Polyketide biosynthesis proteins"
			},
			{
				"name":"01006 Prenyltransferases [BR:scc01006]",
				"children":[
				{
					"name":"Spico_0693 Undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"Spico_0904 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				}
				]
			},
			{
				"name":"01007 Amino acid related enzymes [BR:scc01007]",
				"children":[
				{
					"name":"Spico_1489 lysyl-tRNA synthetase\tK04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]"
				},
				{
					"name":"Spico_0982 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Spico_0948 glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Spico_0980 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Spico_1376 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"Spico_0379 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Spico_1005 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Spico_0705 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Spico_0522 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Spico_0387 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0420 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_1492 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0089 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Spico_0126 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Spico_0886 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Spico_0528 histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Spico_0981 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Spico_0915 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Spico_0119 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Spico_0219 Ser-tRNA(Thr) hydrolase; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Spico_1103 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_1301 Alanyl-tRNA synthetase, class IIc\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_1289 phenylalanyl-tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_1288 phenylalanyl-tRNA synthetase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_1045 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Spico_0778 LL-diaminopimelate aminotransferase apoenzyme\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"Spico_1425 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Spico_1064 2-amino-3-ketobutyrate coenzyme A ligase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Spico_0441 serine palmitoyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"Spico_1433 Cystathionine beta-lyase\tK14155 patB; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"Spico_1771 Acetylornithine\/succinyldiaminopimelate aminotransferase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"Spico_1331 aminotransferase class IV\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_1617 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Spico_0402 phosphoserine aminotransferase apoenzyme\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00199 Cytochrome P450"
			},
			{
				"name":"00194 Photosynthesis proteins [BR:scc00194]"
			}
			]
		},
		{
			"name":"09182 Protein families: genetic information processing",
			"children":[
			{
				"name":"03000 Transcription factors [BR:scc03000]",
				"children":[
				{
					"name":"Spico_1654 transcriptional regulator, DeoR family\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"Spico_1556 transcriptional regulator, DeoR family\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"Spico_0077 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_0101 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_0341 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_0492 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_1260 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_1542 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_1575 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_1663 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Spico_1815 transcriptional regulator, LacI family\tK05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG"
				},
				{
					"name":"Spico_0717 transcriptional regulator, GntR family with LacI sensor\tK02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor"
				},
				{
					"name":"Spico_0012 transcriptional regulator, GntR family with UTRA sensor domain\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"Spico_0022 transcriptional regulator, GntR family with UTRA sensor domain\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Spico_0403 putative transcriptional regulator, AsnC family\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"Spico_1317 putative transcriptional regulator, Crp\/Fnr family\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Spico_0425 transcriptional regulator, Crp\/Fnr family\tK21562 flp; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"Spico_0574 transcriptional regulator, BadM\/Rrf2 family\tK17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor"
				},
				{
					"name":"Spico_0575 transcriptional regulator, BadM\/Rrf2 family\tK17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor"
				},
				{
					"name":"Spico_0712 regulatory protein ArsR\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"Spico_0958 Iron dependent repressor, N-terminal protein\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"Spico_1313 iron (metal) dependent repressor, DtxR family\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"Spico_1006 biotin\/acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Spico_0302 Trp repressor\tK03720 trpR; TrpR family transcriptional regulator, trp operon repressor"
				},
				{
					"name":"Spico_0013 sigma54 specific transcriptional regulator, Fis family\tK21405 acoR; sigma-54 dependent transcriptional regulator, acetoin dehydrogenase operon transcriptional activator AcoR"
				},
				{
					"name":"Spico_0217 Redox-sensing transcriptional repressor rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"Spico_1471 Redox-sensing transcriptional repressor rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"Spico_0179 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"Spico_0246 hypothetical protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"Spico_0167 protein of unknown function DUF156\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"Spico_1862 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Spico_1598 transcriptional regulator, CarD family\tK07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription"
				},
				{
					"name":"Spico_1785 arginine repressor, ArgR\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"Spico_0141 Sigma 54 interacting domain protein\tK03974 pspF; psp operon transcriptional activator"
				},
				{
					"name":"Spico_0291 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Spico_0680 Transcriptional repressor nrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"Spico_0656 Protein mraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			},
			{
				"name":"03021 Transcription machinery [BR:scc03021]",
				"children":[
				{
					"name":"Spico_0685 helicase domain protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1691 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1722 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1721 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Spico_0618 RNA polymerase, sigma 70 subunit, RpoD\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Spico_0629 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Spico_0380 RNA polymerase, sigma-24 subunit, ECF subfamily\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"Spico_1586 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"Spico_0593 NusA antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"Spico_0478 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"Spico_1727 transcription antitermination protein nusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"Spico_0291 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Spico_1234 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				}
				]
			},
			{
				"name":"03019 Messenger RNA biogenesis [BR:scc03019]",
				"children":[
				{
					"name":"Spico_0520 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Spico_1689 2,3 cyclic-nucleotide 2-phosphodiesterase\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"Spico_1330 DEAD\/DEAH box helicase domain protein\tK03732 rhlB; ATP-dependent RNA helicase RhlB [EC:5.6.2.7]"
				},
				{
					"name":"Spico_0305 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Spico_0432 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Spico_0599 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"Spico_1234 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"Spico_1788 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Spico_0529 poly(A) polymerase\tK00970 pcnB; poly(A) polymerase [EC:2.7.7.19]"
				}
				]
			},
			{
				"name":"03041 Spliceosome"
			},
			{
				"name":"03011 Ribosome [BR:scc03011]",
				"children":[
				{
					"name":"Spico_0613 RNA binding S1 domain protein\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"Spico_0690 SSU ribosomal protein S2P\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"Spico_1710 SSU ribosomal protein S3P\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"Spico_1692 SSU ribosomal protein S4P\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"Spico_1699 SSU ribosomal protein S5P\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"Spico_0702 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"Spico_1719 SSU ribosomal protein S7P\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"Spico_1702 SSU ribosomal protein S8P\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"Spico_1191 SSU ribosomal protein S9P\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"Spico_1717 SSU ribosomal protein S10P\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"Spico_1693 SSU ribosomal protein S11P\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"Spico_1720 SSU ribosomal protein S12P\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"Spico_1694 SSU ribosomal protein S13P\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"Spico_1703 SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"Spico_0598 SSU ribosomal protein S15P\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"Spico_0510 SSU ribosomal protein S16P\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"Spico_1707 SSU ribosomal protein S17P\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"Spico_0700 SSU ribosomal protein S18P\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"Spico_1712 SSU ribosomal protein S19P\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"Spico_1238 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"Spico_0398 SSU ribosomal protein S21P\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"Spico_1725 LSU ribosomal protein L1P\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"Spico_1713 LSU ribosomal protein L2P\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"Spico_1716 LSU ribosomal protein L3P\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"Spico_1715 LSU ribosomal protein L4P\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"Spico_1704 LSU ribosomal protein L5P\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"Spico_1701 LSU ribosomal protein L6P\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"Spico_0698 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"Spico_1724 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"Spico_1726 LSU ribosomal protein L11P\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"Spico_1723 LSU ribosomal protein L12P\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"Spico_1192 LSU ribosomal protein L13P\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"Spico_1706 LSU ribosomal protein L14P\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"Spico_1697 LSU ribosomal protein L15P\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"Spico_1709 LSU ribosomal protein L16P\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"Spico_1690 LSU ribosomal protein L17P\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"Spico_1700 LSU ribosomal protein L18P\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"Spico_0514 LSU ribosomal protein L19P\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"Spico_0929 LSU ribosomal protein L20P\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"Spico_1003 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"Spico_1711 LSU ribosomal protein L22P\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"Spico_1714 Ribosomal protein L25\/L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"Spico_1705 LSU ribosomal protein L24P\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"Spico_1002 LSU ribosomal protein L27P\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"Spico_0428 LSU ribosomal protein L28P\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"Spico_1708 LSU ribosomal protein L29P\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"Spico_1698 LSU ribosomal protein L30P\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"Spico_1233 LSU ribosomal protein L31P\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"Spico_0518 LSU ribosomal protein L32P\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"Spico_1729 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"Spico_0005 LSU ribosomal protein L34P\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"Spico_0928 LSU ribosomal protein L35P\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"Spico_1695 LSU ribosomal protein L36P\tK02919 RP-L36; large subunit ribosomal protein L36"
				},
				{
					"name":"Spico_0973 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"Spico_R0002 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0025 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0031 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0004 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0023 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0029 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0005 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0022 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0028 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				}
				]
			},
			{
				"name":"03009 Ribosome biogenesis [BR:scc03009]",
				"children":[
				{
					"name":"Spico_0520 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Spico_0743 Fmu (Sun) domain protein\tK21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]"
				},
				{
					"name":"Spico_1481 GTP-binding protein Era-like-protein\tK03595 era; GTPase"
				},
				{
					"name":"Spico_1001 GTPase obg\tK03979 obgE; GTPase [EC:3.6.5.-]"
				},
				{
					"name":"Spico_0291 transcriptional regulator, TraR\/DksA family\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Spico_0593 NusA antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"Spico_0478 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"Spico_1727 transcription antitermination protein nusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"Spico_1013 Ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Spico_1798 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Spico_1595 Ribosomal RNA small subunit methyltransferase E\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Spico_1836 Ribosomal RNA small subunit methyltransferase E\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Spico_1333 Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Spico_0655 Ribosomal RNA small subunit methyltransferase H\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Spico_0144 Ribosomal RNA small subunit methyltransferase I\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Spico_1687 hemolysin A\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"Spico_1676 RNA methyltransferase, TrmH family, group 3\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Spico_0092 Ribosomal RNA large subunit methyltransferase E\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"Spico_1019 PUA domain containing protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Spico_1359 Ribosomal RNA large subunit methyltransferase L\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"Spico_1102 radical SAM enzyme, Cfr family\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Spico_1350 (Uracil-5)-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Spico_0611 pseudouridine synthase Rsu\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Spico_0451 pseudouridine synthase, RluA family\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Spico_0787 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Spico_1816 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Spico_0512 Ribosome maturation factor rimM\tK02860 rimM; 16S rRNA processing protein RimM"
				},
				{
					"name":"Spico_1195 Ribosomal protein S12 methylthiotransferase rimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
				},
				{
					"name":"Spico_0305 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Spico_0454 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Spico_1684 GTP-binding protein engA\tK03977 engA; GTPase"
				},
				{
					"name":"Spico_1099 GTP-binding proten HflX\tK03665 hflX; GTPase"
				},
				{
					"name":"Spico_0546 SUA5\/yciO\/yrdC domain protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"Spico_1076 (p)ppGpp synthetase I, SpoT\/RelA\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"Spico_0595 Ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
				},
				{
					"name":"Spico_0592 Ribosome maturation factor rimP\tK09748 rimP; ribosome maturation factor RimP"
				},
				{
					"name":"Spico_0997 iojap-like protein\tK09710 ybeB; ribosome-associated protein"
				},
				{
					"name":"Spico_0469 metalloprotease ybeY\tK07042 ybeY; probable rRNA maturation factor"
				},
				{
					"name":"Spico_0898 protein of unknown function UPF0044\tK07574 yhbY; RNA-binding protein"
				},
				{
					"name":"Spico_1098 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
				}
				]
			},
			{
				"name":"03016 Transfer RNA biogenesis [BR:scc03016]",
				"children":[
				{
					"name":"Spico_0543 RNAse Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"Spico_0521 polynucleotide adenylyltransferase\/metal dependent phosphohydrolase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				},
				{
					"name":"Spico_0982 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Spico_0119 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Spico_0522 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Spico_0089 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Spico_0705 methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Spico_0948 glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Spico_1005 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Spico_0126 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Spico_1103 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_1301 Alanyl-tRNA synthetase, class IIc\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Spico_0886 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Spico_0981 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Spico_0219 Ser-tRNA(Thr) hydrolase; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Spico_0915 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Spico_0379 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Spico_0387 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0420 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_1492 valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Spico_0528 histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Spico_1289 phenylalanyl-tRNA synthetase, alpha subunit\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_1288 phenylalanyl-tRNA synthetase beta subunit\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Spico_0980 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Spico_1376 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"Spico_0607 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"Spico_1285 histidine triad (HIT) protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"Spico_0484 tRNA-i(6)A37 thiotransferase enzyme MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"Spico_1009 MiaB-like tRNA modifying enzyme\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				},
				{
					"name":"Spico_0675 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"Spico_1453 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"Spico_0596 tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"Spico_0525 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Spico_0546 SUA5\/yciO\/yrdC domain protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"Spico_0904 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"Spico_1335 tRNA modification GTPase mnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"Spico_1334 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"Spico_0677 inositol monophosphatase\tK01082 cysQ; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				},
				{
					"name":"Spico_0006 Ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"Spico_R0017 RNA component of RNaseP\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"Spico_1315 3'-5' exonuclease\tK03684 rnd; ribonuclease D [EC:3.1.13.5]"
				},
				{
					"name":"Spico_1489 lysyl-tRNA synthetase\tK04566 lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]"
				},
				{
					"name":"Spico_1030 ybaK\/ebsC protein\tK03976 ybaK; Cys-tRNA(Pro)\/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]"
				},
				{
					"name":"Spico_1243 TIM-barrel protein, nifR3 family\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				},
				{
					"name":"Spico_0286 tRNA\/rRNA methyltransferase (SpoU)\tK02533 lasT; tRNA\/rRNA methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"Spico_0513 tRNA (Guanine37-N(1)-) methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"Spico_0913 tRNA\/rRNA methyltransferase (SpoU)\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				},
				{
					"name":"Spico_0283 tRNA-specific 2-thiouridylase mnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"Spico_0586 S-adenosylmethionine--tRNA ribosyltransferase-isomerase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"Spico_0298 protein of unknown function DUF208\tK09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"Spico_0603 tRNA-guanine transglycosylase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"Spico_0524 tRNA sulfurtransferase\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"Spico_0971 tRNA(Ile)-lysidine synthase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"Spico_0933 universal protein YeaZ\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"Spico_0626 O-sialoglycoprotein endopeptidase\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"Spico_0932 Uncharacterized protein family UPF0079, ATPase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"Spico_0599 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				}
				]
			},
			{
				"name":"03012 Translation factors [BR:scc03012]",
				"children":[
				{
					"name":"Spico_0594 bacterial translation initiation factor 2 (bIF-2)\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"Spico_0927 bacterial translation initiation factor 3 (bIF-3)\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"Spico_0688 ABC transporter related protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"Spico_0691 Elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"Spico_1718 translation elongation factor 1A (EF-1A\/EF-Tu)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Spico_0673 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_0674 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_1604 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_1074 bacterial peptide chain release factor 1 (bRF-1)\tK02835 prfA; peptide chain release factor 1"
				},
				{
					"name":"Spico_0692 ribosome recycling factor\tK02838 frr; ribosome recycling factor"
				},
				{
					"name":"Spico_1075 protein-(glutamine-N5) methyltransferase, release factor-specific\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]"
				},
				{
					"name":"Spico_0972 peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
				},
				{
					"name":"Spico_1828 Peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
				},
				{
					"name":"Spico_1083 bacterial translation initiation factor 1 (bIF-1)\tK02518 infA; translation initiation factor IF-1"
				},
				{
					"name":"Spico_1337 translation elongation factor P (EF-P)\tK02356 efp; elongation factor P"
				},
				{
					"name":"Spico_1336 Lysine--tRNA ligase\tK04568 epmA; elongation factor P--(R)-beta-lysine ligase [EC:6.3.1.-]"
				},
				{
					"name":"Spico_0537 bacterial peptide chain release factor 2 (bRF-2)\tK02836 prfB; peptide chain release factor 2"
				}
				]
			},
			{
				"name":"03110 Chaperones and folding catalysts [BR:scc03110]",
				"children":[
				{
					"name":"Spico_0234 ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
				},
				{
					"name":"Spico_0794 ATP-dependent Clp protease ATP-binding subunit ClpX\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
				},
				{
					"name":"Spico_0643 heat shock protein HslVU, ATPase subunit HslU\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU"
				},
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Spico_1677 Chaperone protein dnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"Spico_1846 heat shock protein DnaJ domain protein\tK05801 djlA; DnaJ like chaperone protein"
				},
				{
					"name":"Spico_1358 Hsp33 protein\tK04083 hslO; molecular chaperone Hsp33"
				},
				{
					"name":"Spico_1679 Protein grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"Spico_1119 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Spico_0631 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Spico_0970 membrane protease FtsH catalytic subunit\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
				},
				{
					"name":"Spico_0897 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Spico_1861 Peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"Spico_0852 peptidylprolyl isomerase FKBP-type\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"Spico_1430 FKBP-type peptidyl-prolyl isomerase domain protein\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"Spico_0731 PpiC-type peptidyl-prolyl cis-trans isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"Spico_0477 PpiC-type peptidyl-prolyl cis-trans isomerase\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				},
				{
					"name":"Spico_1054 thioredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"Spico_1180 thioredoxin\tK03671 TXN; thioredoxin"
				}
				]
			},
			{
				"name":"04131 Membrane trafficking [BR:scc04131]",
				"children":[
				{
					"name":"Spico_1282 Alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"Spico_1061 Hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_0471 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Spico_0424 phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"Spico_0349 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Spico_0376 major facilitator superfamily MFS_1\tK06902 UMF1; MFS transporter, UMF1 family"
				}
				]
			},
			{
				"name":"04121 Ubiquitin system [BR:scc04121]"
			},
			{
				"name":"03051 Proteasome [BR:scc03051]",
				"children":[
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"03032 DNA replication proteins [BR:scc03032]",
				"children":[
				{
					"name":"Spico_0730 RNase HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"Spico_1237 histone family protein DNA-binding protein\tK04764 ihfA; integration host factor subunit alpha"
				},
				{
					"name":"Spico_0001 chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Spico_0697 replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"Spico_0619 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1795 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0002 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1591 DNA polymerase III delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0281 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0635 hypothetical protein\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1840 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0507 Ribonuclease H\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Spico_0552 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"Spico_1865 DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1866 DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1817 DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1818 DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1096 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Spico_0781 DNA topoisomerase III\tK03169 topB; DNA topoisomerase III [EC:5.6.2.1]"
				}
				]
			},
			{
				"name":"03036 Chromosome and associated proteins [BR:scc03036]",
				"children":[
				{
					"name":"Spico_0520 RNAse III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_1237 histone family protein DNA-binding protein\tK04764 ihfA; integration host factor subunit alpha"
				},
				{
					"name":"Spico_0001 chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Spico_0232 Ferritin Dps family protein\tK04047 dps; starvation-inducible DNA-binding protein"
				},
				{
					"name":"Spico_0508 SMC domain protein\tK03529 smc; chromosome segregation protein"
				},
				{
					"name":"Spico_0609 chromosome segregation and condensation protein ScpA\tK05896 scpA; segregation and condensation protein A"
				},
				{
					"name":"Spico_0610 chromosome segregation and condensation protein, ScpB\tK06024 scpB; segregation and condensation protein B"
				},
				{
					"name":"Spico_0649 cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"Spico_0641 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Spico_1332 cell division protein FtsK\/SpoIIIE\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family"
				},
				{
					"name":"Spico_0650 Polypeptide-transport-associated domain protein FtsQ-type\tK03589 ftsQ; cell division protein FtsQ"
				},
				{
					"name":"Spico_0651 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Spico_0034 Tubulin\/FtsZ GTPase\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_0648 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_0917 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Spico_0746 Cobyrinic acid ac-diamide synthase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Spico_1863 chromosome segregation ATPase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Spico_1862 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Spico_1817 DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1818 DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1334 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"Spico_1333 Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Spico_0647 Tyrosine recombinase xerC\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"Spico_1308 ATPase-like, ParA\/MinD\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"Spico_0182 filamentation induced by cAMP protein Fic\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]"
				},
				{
					"name":"Spico_0194 filamentation induced by cAMP protein Fic\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]"
				},
				{
					"name":"Spico_0767 filamentation induced by cAMP protein Fic\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]"
				},
				{
					"name":"Spico_1361 filamentation induced by cAMP protein Fic\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]"
				}
				]
			},
			{
				"name":"03400 DNA repair and recombination proteins [BR:scc03400]",
				"children":[
				{
					"name":"Spico_0044 methylated-DNA\/protein-cysteinemethyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Spico_0358 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
				},
				{
					"name":"Spico_0977 Uracil-DNA glycosylase superfamily\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
				},
				{
					"name":"Spico_0288 HhH-GPD family protein\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"Spico_0856 DNA-(apurinic or apyrimidinic site) lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_0843 DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_1824 DNA-(apurinic or apyrimidinic site) lyase\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Spico_0685 helicase domain protein\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0032 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Spico_1218 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Spico_0600 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"Spico_1452 phage SPO1 DNA polymerase-related protein\tK21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"Spico_1497 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Spico_0748 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Spico_0397 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Spico_1790 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Spico_1344 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0465 Excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Spico_0943 Excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"Spico_1592 UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"Spico_0744 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1194 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1722 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1721 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Spico_1691 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"Spico_0676 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0590 DNA mismatch repair protein mutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Spico_0455 DNA mismatch repair protein MutS domain protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"Spico_0405 DNA mismatch repair protein mutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"Spico_1062 Exodeoxyribonuclease I\tK01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]"
				},
				{
					"name":"Spico_0783 Exodeoxyribonuclease 7 large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"Spico_0784 Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"Spico_1795 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0002 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1591 DNA polymerase III delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0281 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0635 hypothetical protein\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1840 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_0552 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"Spico_0608 RecA protein\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"Spico_0584 Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"Spico_0585 Holliday junction DNA helicase subunit RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0583 Crossover junction endodeoxyribonuclease ruvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"Spico_1451 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1860 DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
				},
				{
					"name":"Spico_0003 DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"Spico_0133 putative transcriptional regulator\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1161 putative transcriptional regulator\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1797 ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Spico_1841 DNA replication and repair protein RecR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"Spico_0660 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"Spico_1131 CRISPR-associated protein, Cas1 family\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"Spico_1155 CRISPR-associated protein, Cas1 family\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"Spico_1865 DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1866 DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1096 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Spico_1237 histone family protein DNA-binding protein\tK04764 ihfA; integration host factor subunit alpha"
				},
				{
					"name":"Spico_0432 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Spico_0912 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"Spico_1590 SOS-response transcriptional repressor, LexA\tK01356 lexA; repressor LexA [EC:3.4.21.88]"
				},
				{
					"name":"Spico_1190 Regulatory protein recX\tK03565 recX; regulatory protein"
				},
				{
					"name":"Spico_0632 helicase c2\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"Spico_1766 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_1765 ribonucleotide reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Spico_0795 phosphoesterase RecJ domain protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			},
			{
				"name":"03029 Mitochondrial biogenesis [BR:scc03029]",
				"children":[
				{
					"name":"Spico_0594 bacterial translation initiation factor 2 (bIF-2)\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"Spico_0927 bacterial translation initiation factor 3 (bIF-3)\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"Spico_0691 Elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"Spico_1718 translation elongation factor 1A (EF-1A\/EF-Tu)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Spico_0673 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_0674 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_1604 translation elongation factor 2 (EF-2\/EF-G)\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Spico_1481 GTP-binding protein Era-like-protein\tK03595 era; GTPase"
				},
				{
					"name":"Spico_0980 tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Spico_0089 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Spico_0126 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Spico_0981 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Spico_1005 arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Spico_0743 Fmu (Sun) domain protein\tK21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]"
				},
				{
					"name":"Spico_1437 DNA\/RNA non-specific endonuclease\tK01173 ENDOG; endonuclease G, mitochondrial"
				},
				{
					"name":"Spico_0701 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_1055 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Spico_0589 outer membrane protein assembly complex, YaeT protein\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_1679 Protein grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Spico_0631 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Spico_1677 Chaperone protein dnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"Spico_0525 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Spico_1308 ATPase-like, ParA\/MinD\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"Spico_0007 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			}
			]
		},
		{
			"name":"09183 Protein families: signaling and cellular processes",
			"children":[
			{
				"name":"02000 Transporters [BR:scc02000]",
				"children":[
				{
					"name":"Spico_1536 Xenobiotic-transporting ATPase\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1535 Xenobiotic-transporting ATPase\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_0172 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1273 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1521 Xenobiotic-transporting ATPase\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_0171 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1272 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1520 Xenobiotic-transporting ATPase\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Spico_1329 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Spico_0272 extracellular solute-binding protein family 1\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"Spico_0310 extracellular solute-binding protein family 1\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"Spico_0273 binding-protein-dependent transport systems inner membrane component\tK02011 afuB; iron(III) transport system permease protein"
				},
				{
					"name":"Spico_0311 binding-protein-dependent transport systems inner membrane component\tK02011 afuB; iron(III) transport system permease protein"
				},
				{
					"name":"Spico_0274 Polyamine-transporting ATPase\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]"
				},
				{
					"name":"Spico_0312 Polyamine-transporting ATPase\tK02010 afuC; iron(III) transport system ATP-binding protein [EC:7.2.2.7]"
				},
				{
					"name":"Spico_0940 ABC transporter, periplasmic binding protein, thiB subfamily\tK02064 thiB; thiamine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0941 binding-protein-dependent transport systems inner membrane component\tK02063 thiP; thiamine transport system permease protein"
				},
				{
					"name":"Spico_0942 Fe(3+)-transporting ATPase\tK02062 thiQ; thiamine transport system ATP-binding protein [EC:7.6.2.15]"
				},
				{
					"name":"Spico_0850 extracellular solute-binding protein family 1\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"Spico_1297 extracellular solute-binding protein family 1\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0849 binding-protein-dependent transport systems inner membrane component\tK11070 potC; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"Spico_0848 binding-protein-dependent transport systems inner membrane component\tK11071 potB; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"Spico_0847 spermidine\/putrescine ABC transporter ATPase subunit\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]"
				},
				{
					"name":"Spico_0351 hypothetical protein\tK02051 ABC.SN.S; NitT\/TauT family transport system substrate-binding protein"
				},
				{
					"name":"Spico_0352 binding-protein-dependent transport systems inner membrane component\tK02050 ABC.SN.P; NitT\/TauT family transport system permease protein"
				},
				{
					"name":"Spico_0353 Fe(3+)-transporting ATPase\tK02049 ABC.SN.A; NitT\/TauT family transport system ATP-binding protein"
				},
				{
					"name":"Spico_0269 carbohydrate ABC transporter ATP-binding protein, CUT1 family\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_0447 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK25086 musE; maltose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1541 extracellular solute-binding protein family 1\tK25086 musE; maltose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0446 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK25087 musF; maltose transport system permease protein"
				},
				{
					"name":"Spico_1540 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK25087 musF; maltose transport system permease protein"
				},
				{
					"name":"Spico_0445 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK25088 musG; maltose transport system permease protein"
				},
				{
					"name":"Spico_1539 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK25088 musG; maltose transport system permease protein"
				},
				{
					"name":"Spico_0259 extracellular solute-binding protein family 1\tK10117 msmE; raffinose\/stachyose\/melibiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0893 extracellular solute-binding protein family 1\tK10117 msmE; raffinose\/stachyose\/melibiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0260 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK10118 msmF; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0895 binding-protein-dependent transport systems inner membrane component\tK10118 msmF; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0261 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10119 msmG; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0894 binding-protein-dependent transport systems inner membrane component\tK10119 msmG; raffinose\/stachyose\/melibiose transport system permease protein"
				},
				{
					"name":"Spico_0723 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK10240 cebE; cellobiose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0722 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK10241 cebF; cellobiose transport system permease protein"
				},
				{
					"name":"Spico_0721 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10242 cebG; cellobiose transport system permease protein"
				},
				{
					"name":"Spico_1210 extracellular solute-binding protein family 1\tK10192 togB; oligogalacturonide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1209 binding-protein-dependent transport systems inner membrane component\tK10193 togM; oligogalacturonide transport system permease protein"
				},
				{
					"name":"Spico_1208 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK10194 togN; oligogalacturonide transport system permease protein"
				},
				{
					"name":"Spico_1279 extracellular solute-binding protein family 1\tK17241 aguE; alpha-1,4-digalacturonate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1280 binding-protein-dependent transport systems inner membrane component\tK17242 aguF; alpha-1,4-digalacturonate transport system permease protein"
				},
				{
					"name":"Spico_1281 binding-protein-dependent transport systems inner membrane component\tK17243 aguG; alpha-1,4-digalacturonate transport system permease protein"
				},
				{
					"name":"Spico_0058 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0362 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0385 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0500 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0714 sugar ABC transporter substrate-binding protein\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1072 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1532 extracellular solute-binding protein family 1\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0056 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0364 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0383 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0494 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0716 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1071 binding-protein-dependent transport systems inner membrane component\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1534 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0057 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0363 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0382 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0493 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_0715 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1070 binding-protein-dependent transport systems inner membrane component\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1533 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"Spico_1400 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				},
				{
					"name":"Spico_1404 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10540 mglB; methyl-galactoside transport system substrate-binding protein"
				},
				{
					"name":"Spico_1398 monosaccharide ABC transporter membrane protein, CUT2 family\tK10541 mglC; methyl-galactoside transport system permease protein"
				},
				{
					"name":"Spico_1399 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10542 mglA; methyl-galactoside transport system ATP-binding protein [EC:7.5.2.11]"
				},
				{
					"name":"Spico_1659 rhamnose-binding protein\tK10559 rhaS; rhamnose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1657 inner-membrane translocator\tK10560 rhaP; rhamnose transport system permease protein"
				},
				{
					"name":"Spico_1656 inner-membrane translocator\tK10561 rhaQ; rhamnose transport system permease protein"
				},
				{
					"name":"Spico_1658 Monosaccharide-transporting ATPase\tK10562 rhaT; rhamnose transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_0014 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0078 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0097 bifunctional carbohydrate binding and transport protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1403 hypothetical protein\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1629 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1644 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_1814 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0016 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0079 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0099 inner-membrane translocator\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0100 inner-membrane translocator\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1628 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1645 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_1812 monosaccharide ABC transporter membrane protein, CUT2 family\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Spico_0015 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0081 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0098 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1626 monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1627 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1646 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_1813 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Spico_0335 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK23508 ytfQ; galactofuranose transport system substrate-binding protein"
				},
				{
					"name":"Spico_0337 monosaccharide ABC transporter membrane protein, CUT2 family\tK23509 ytfT; galactofuranose transport system permease protein"
				},
				{
					"name":"Spico_0338 monosaccharide ABC transporter membrane protein, CUT2 family\tK23509 ytfT; galactofuranose transport system permease protein"
				},
				{
					"name":"Spico_0336 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK10820 ytfR; galactofuranose transport system ATP-binding protein [EC:7.5.2.9]"
				},
				{
					"name":"Spico_1039 sugar ABC transporter (sugar-binding protein)\tK17213 K17213; inositol transport system substrate-binding protein"
				},
				{
					"name":"Spico_1037 inner-membrane translocator\tK17214 K17214; inositol transport system permease protein"
				},
				{
					"name":"Spico_1038 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK17215 K17215; inositol transport system ATP-binding protein"
				},
				{
					"name":"Spico_1415 extracellular solute-binding protein family 1\tK05813 ugpB; sn-glycerol 3-phosphate transport system substrate-binding protein"
				},
				{
					"name":"Spico_1413 binding-protein-dependent transport systems inner membrane component\tK05814 ugpA; sn-glycerol 3-phosphate transport system permease protein"
				},
				{
					"name":"Spico_1414 binding-protein-dependent transport systems inner membrane component\tK05815 ugpE; sn-glycerol 3-phosphate transport system permease protein"
				},
				{
					"name":"Spico_0669 extracellular solute-binding protein family 1\tK25676 yesO; pectin-derived oligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"Spico_0869 extracellular solute-binding protein family 1\tK25676 yesO; pectin-derived oligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"Spico_0667 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK25677 yesP; pectin-derived oligosaccharide transport system permease protein"
				},
				{
					"name":"Spico_0868 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK25677 yesP; pectin-derived oligosaccharide transport system permease protein"
				},
				{
					"name":"Spico_0668 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK25678 yesQ; pectin-derived oligosaccharide transport system permease protein"
				},
				{
					"name":"Spico_0867 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK25678 yesQ; pectin-derived oligosaccharide transport system permease protein"
				},
				{
					"name":"Spico_0062 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"Spico_1112 basic membrane lipoprotein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"Spico_0064 nucleoside ABC transporter membrane protein\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_1110 inner-membrane translocator\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_0065 nucleoside ABC transporter membrane protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_1109 nucleoside ABC transporter membrane protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"Spico_0063 nucleoside ABC transporter ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"Spico_1111 nucleoside ABC transporter ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"Spico_0173 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_1049 extracellular solute-binding protein family 1\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_1383 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_1487 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_1739 carbohydrate ABC transporter substrate-binding protein, CUT1 family\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_0174 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1048 binding-protein-dependent transport systems inner membrane component\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1368 binding-protein-dependent transport systems inner membrane component\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1384 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1486 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1737 carbohydrate ABC transporter membrane protein 1, CUT1 family\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_0175 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1047 binding-protein-dependent transport systems inner membrane component\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1367 binding-protein-dependent transport systems inner membrane component\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1385 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1485 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1736 carbohydrate ABC transporter membrane protein 2, CUT1 family\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"Spico_1259 monosaccharide ABC transporter substrate-binding protein, CUT2 family\tK02058 ABC.SS.S; simple sugar transport system substrate-binding protein"
				},
				{
					"name":"Spico_1256 inner-membrane translocator\tK02057 ABC.SS.P; simple sugar transport system permease protein"
				},
				{
					"name":"Spico_1257 monosaccharide ABC transporter membrane protein, CUT2 family\tK02057 ABC.SS.P; simple sugar transport system permease protein"
				},
				{
					"name":"Spico_1670 monosaccharide ABC transporter membrane protein, CUT2 family\tK02057 ABC.SS.P; simple sugar transport system permease protein"
				},
				{
					"name":"Spico_1671 monosaccharide ABC transporter membrane protein, CUT2 family\tK02057 ABC.SS.P; simple sugar transport system permease protein"
				},
				{
					"name":"Spico_1258 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK02056 ABC.SS.A; simple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_1672 monosaccharide ABC transporter ATP-binding protein, CUT2 family\tK02056 ABC.SS.A; simple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"Spico_0435 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Spico_0436 phosphate ABC transporter membrane protein 1, PhoT family\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Spico_0437 phosphate ABC transporter, inner membrane subunit PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Spico_0438 phosphate ABC transporter ATP-binding protein, PhoT family\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Spico_1408 amino acid ABC transporter substrate-binding protein, PAAT family\tK10039 peb1A; aspartate\/glutamate\/glutamine transport system substrate-binding protein"
				},
				{
					"name":"Spico_1406 amino acid ABC transporter membrane protein 2, PAAT family\tK10040 peb1B; aspartate\/glutamate\/glutamine transport system permease protein"
				},
				{
					"name":"Spico_1407 amino acid ABC transporter membrane protein 1, PAAT family\tK10040 peb1B; aspartate\/glutamate\/glutamine transport system permease protein"
				},
				{
					"name":"Spico_1409 amino acid ABC transporter ATP-binding protein, PAAT family\tK10041 peb1C; aspartate\/glutamate\/glutamine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"Spico_0107 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0879 amino acid\/amide ABC transporter substrate-binding protein, HAAT family\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1092 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_1580 Extracellular ligand-binding receptor\tK01999 livK; branched-chain amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0108 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0880 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1091 amino acid\/amide ABC transporter membrane protein 1, HAAT family\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1579 inner-membrane translocator\tK01997 livH; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0109 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0881 amino acid\/amide ABC transporter membrane protein 2, HAAT family\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1090 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_1578 inner-membrane translocator\tK01998 livM; branched-chain amino acid transport system permease protein"
				},
				{
					"name":"Spico_0110 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0882 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1089 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1577 amino acid\/amide ABC transporter ATP-binding protein 1, HAAT family\tK01995 livG; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0111 ABC transporter related protein\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0883 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1088 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_1576 amino acid\/amide ABC transporter ATP-binding protein 2, HAAT family\tK01996 livF; branched-chain amino acid transport system ATP-binding protein"
				},
				{
					"name":"Spico_0227 NLPA lipoprotein\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0226 binding-protein-dependent transport systems inner membrane component\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"Spico_0225 Sulfate-transporting ATPase\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"Spico_0991 ABC transporter substrate binding protein\tK01989 K01989; putative tryptophan\/tyrosine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0992 ABC transporter substrate binding protein\tK01989 K01989; putative tryptophan\/tyrosine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0993 ABC transporter substrate binding protein\tK01989 K01989; putative tryptophan\/tyrosine transport system substrate-binding protein"
				},
				{
					"name":"Spico_0994 inner-membrane translocator\tK05832 K05832; putative tryptophan\/tyrosine transport system permease protein"
				},
				{
					"name":"Spico_0995 Phosphonate-transporting ATPase\tK05833 K05833; putative tryptophan\/tyrosine transport system ATP-binding protein"
				},
				{
					"name":"Spico_0317 amino acid ABC transporter substrate-binding protein, PAAT family\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0736 extracellular solute-binding protein family 3\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0737 extracellular solute-binding protein family 3\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein"
				},
				{
					"name":"Spico_0316 amino acid ABC transporter membrane protein, PAAT family\tK02029 ABC.PA.P; polar amino acid transport system permease protein"
				},
				{
					"name":"Spico_0739 amino acid ABC transporter membrane protein, PAAT family\tK02029 ABC.PA.P; polar amino acid transport system permease protein"
				},
				{
					"name":"Spico_0315 amino acid ABC transporter ATP-binding protein, PAAT family\tK02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"Spico_0740 amino acid ABC transporter ATP-binding protein, PAAT family\tK02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"Spico_1201 extracellular solute-binding protein family 5\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"Spico_1196 binding-protein-dependent transport systems inner membrane component\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1197 binding-protein-dependent transport systems inner membrane component\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"Spico_1198 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1199 oligopeptide\/dipeptide ABC transporter, ATPase subunit\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"Spico_1596 extracellular solute-binding protein family 5\tK02035 ABC.PE.S; peptide\/nickel transport system substrate-binding protein"
				},
				{
					"name":"Spico_1124 periplasmic binding protein\tK25282 yclQ; iron-siderophore transport system substrate-binding protein"
				},
				{
					"name":"Spico_1122 transport system permease protein\tK25283 yclO; iron-siderophore transport system permease protein"
				},
				{
					"name":"Spico_1121 transport system permease protein\tK25284 yclN; iron-siderophore transport system permease protein"
				},
				{
					"name":"Spico_1123 Iron-chelate-transporting ATPase\tK25285 yclP; iron-siderophore transport system ATP-binding protein [EC:7.2.2.-]"
				},
				{
					"name":"Spico_0072 ABC transporter related protein\tK02013 ABC.FEV.A; iron complex transport system ATP-binding protein [EC:7.2.2.-]"
				},
				{
					"name":"Spico_1668 periplasmic solute binding protein\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"Spico_0223 ABC-3 protein\tK09816 znuB; zinc transport system permease protein"
				},
				{
					"name":"Spico_0224 Fe(3+)-transporting ATPase\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]"
				},
				{
					"name":"Spico_1007 BioY protein\tK03523 bioY; biotin transport system substrate-specific component"
				},
				{
					"name":"Spico_1114 cobalt transport protein\tK16783 bioN; biotin transport system permease protein"
				},
				{
					"name":"Spico_1113 Fe(3+)-transporting ATPase\tK16784 bioM; biotin transport system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Spico_1396 protein of unknown function DUF1393\tK16924 mtsT; energy-coupling factor transport system substrate-specific component"
				},
				{
					"name":"Spico_1326 cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"Spico_1394 cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"Spico_1327 ABC transporter related protein\tK01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"Spico_1395 Monosaccharide-transporting ATPase\tK01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"Spico_0601 permease YjgP\/YjgQ family protein\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Spico_0602 permease YjgP\/YjgQ family protein\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Spico_1585 Fe(3+)-transporting ATPase\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Spico_0540 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Spico_0542 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Spico_0541 Phosphonate-transporting ATPase\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Spico_1496 protein of unknown function DUF990\tK25154 evrC; viologen exporter family transport system permease protein"
				},
				{
					"name":"Spico_1494 protein of unknown function DUF990\tK25155 evrB; viologen exporter family transport system permease protein"
				},
				{
					"name":"Spico_1495 ABC transporter related protein\tK25156 evrA; viologen exporter family transport system ATP-binding protein"
				},
				{
					"name":"Spico_0249 ABC-2 type transporter\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"Spico_0709 hypothetical protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"Spico_0250 Polyamine-transporting ATPase\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Spico_0565 ABC transporter related protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Spico_0710 ABC transporter related protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Spico_1203 Polyamine-transporting ATPase\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Spico_1609 ABC transporter related protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Spico_0161 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Spico_1354 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Spico_0160 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Spico_1355 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Spico_1764 Iron-regulated ABC transporter ATPase subunit SufC\tK09013 sufC; Fe-S cluster assembly ATP-binding protein"
				},
				{
					"name":"Spico_1012 MATE efflux family protein\tK26939 norM; MATE family, multidrug efflux pump"
				},
				{
					"name":"Spico_0996 MATE efflux family protein\tK26937 dinF; MATE family, multidrug efflux pump"
				},
				{
					"name":"Spico_1548 MATE efflux family protein\tK26937 dinF; MATE family, multidrug efflux pump"
				},
				{
					"name":"Spico_1849 MATE efflux family protein\tK26937 dinF; MATE family, multidrug efflux pump"
				},
				{
					"name":"Spico_0369 major facilitator superfamily MFS_1\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				},
				{
					"name":"Spico_0376 major facilitator superfamily MFS_1\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"Spico_1508 phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"Spico_1685 phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"Spico_1509 Phosphotransferase system, phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"Spico_1589 Phosphotransferase system, phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"Spico_0753 putative PTS IIA-like nitrogen-regulatory protein PtsN\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"Spico_1116 putative PTS IIA-like nitrogen-regulatory protein PtsN\tK02806 ptsN; nitrogen PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"Spico_0091 formate\/nitrite transporter\tK02598 nirC; nitrite transporter"
				},
				{
					"name":"Spico_1360 Large-conductance mechanosensitive channel\tK03282 mscL; large conductance mechanosensitive channel"
				},
				{
					"name":"Spico_1819 MscS Mechanosensitive ion channel\tK03442 mscS; small conductance mechanosensitive channel"
				},
				{
					"name":"Spico_1021 Mg2 transporter protein CorA family protein\tK03284 corA; magnesium transporter"
				},
				{
					"name":"Spico_0162 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"Spico_0589 outer membrane protein assembly complex, YaeT protein\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Spico_1584 hypothetical protein\tK09774 lptA; lipopolysaccharide export system protein LptA"
				},
				{
					"name":"Spico_0470 CBS domain containing protein\tK06189 corC; hemolysin (HlyC) family protein"
				},
				{
					"name":"Spico_1339 major facilitator superfamily MFS_1\tK16211 malY; maltose\/moltooligosaccharide transporter"
				},
				{
					"name":"Spico_1222 zinc\/iron permease\tK07238 TC.ZIP; zinc transporter, ZIP family"
				},
				{
					"name":"Spico_0165 protein of unknown function DUF6 transmembrane\tK08978 TC.BAT1; bacterial\/archaeal transporter family protein"
				},
				{
					"name":"Spico_0289 protein of unknown function DUF606\tK09936 TC.BAT2; bacterial\/archaeal transporter family-2 protein"
				},
				{
					"name":"Spico_1854 Na+\/glutamate symporter-like protein\tK03312 gltS; glutamate:Na+ symporter, ESS family"
				},
				{
					"name":"Spico_1175 H(+)-transporting two-sector ATPase\tK03498 trkH; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"Spico_1177 cation transporter\tK03498 trkH; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"Spico_1174 TrkA-N domain protein\tK03499 trkA; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"Spico_1176 TrkA-N domain protein\tK03499 trkA; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"Spico_1605 Xanthine\/uracil\/vitamin C permease\tK02824 uraA; uracil permease"
				},
				{
					"name":"Spico_0921 Xanthine\/uracil\/vitamin C permease\tK06901 pbuG; adenine\/guanine\/hypoxanthine permease"
				},
				{
					"name":"Spico_1779 TRAP C4-dicarboxylate transport system permease DctM subunit\tK03326 TC.DCUC; C4-dicarboxylate transporter, DcuC family"
				},
				{
					"name":"Spico_0604 integral membrane protein MviN\tK03980 murJ; putative peptidoglycan lipid II flippase"
				},
				{
					"name":"Spico_1101 Oligopeptide transporter OPT superfamily protein\tK28868 K28868; oligopeptide transporter family protein"
				},
				{
					"name":"Spico_1219 Auxin Efflux Carrier\tK24180 mleP; malate permease and related proteins"
				},
				{
					"name":"Spico_0772 AzlC family protein\tK26605 azlC; branched chain amino acid efflux pump"
				},
				{
					"name":"Spico_0773 branched-chain amino acid transport\tK26606 azlD; branched chain amino acid efflux pump"
				},
				{
					"name":"Spico_0391 protein of unknown function DUF165\tK09125 yhhQ; queuosine precursor transporter"
				},
				{
					"name":"Spico_0678 protein of unknown function DUF165\tK09125 yhhQ; queuosine precursor transporter"
				},
				{
					"name":"Spico_0651 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Spico_1858 protein of unknown function DUF340 membrane\tK28370 lysO; lysine exporter"
				},
				{
					"name":"Spico_0426 Inorganic diphosphatase\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]"
				},
				{
					"name":"Spico_0318 sodium ion-translocating decarboxylase, beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_1173 glutaconyl-CoA decarboxylase beta subunit\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"Spico_0959 FeoA family protein\tK04758 feoA; ferrous iron transport protein A"
				},
				{
					"name":"Spico_0960 FeoA family protein\tK04758 feoA; ferrous iron transport protein A"
				},
				{
					"name":"Spico_0961 ferrous iron transport protein B\tK04759 feoB; ferrous iron transport protein B"
				},
				{
					"name":"Spico_1480 MgtC\/SapB transporter\tK07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein"
				}
				]
			},
			{
				"name":"02044 Secretion system [BR:scc02044]",
				"children":[
				{
					"name":"Spico_1796 protein of unknown function YGGT\tK02221 yggT; YggT family protein"
				},
				{
					"name":"Spico_1311 dCMP deaminase\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"Spico_0639 protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Spico_0214 protein-export membrane protein SecD\tK03072 secD; preprotein translocase subunit SecD"
				},
				{
					"name":"Spico_1728 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Spico_0474 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Spico_1696 protein translocase subunit secY\/sec61 alpha\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Spico_0509 signal recognition particle subunit FFH\/SRP54 (srp54)\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Spico_0539 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Spico_0213 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Spico_0007 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				}
				]
			},
			{
				"name":"02042 Bacterial toxins [BR:scc02042]",
				"children":[
				{
					"name":"Spico_0162 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				}
				]
			},
			{
				"name":"02022 Two-component system [BR:scc02022]",
				"children":[
				{
					"name":"Spico_0393 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0421 multi-sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0422 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Spico_1352 two component, sigma54 specific, transcriptional regulator, Fis family\tK07714 atoC; two-component system, NtrC family, response regulator AtoC"
				},
				{
					"name":"Spico_0178 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1382 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1402 multi-sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_1740 integral membrane sensor signal transduction histidine kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"Spico_0177 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1206 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1381 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1401 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1624 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1741 two component transcriptional regulator, AraC family\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"Spico_1783 ANTAR domain protein\tK22010 pdtaR; two-component system, response regulator PdtaR"
				}
				]
			},
			{
				"name":"02035 Bacterial motility proteins [BR:scc02035]",
				"children":[
				{
					"name":"Spico_0642 GTP-binding signal recognition particle SRP54 G-domain protein\tK02404 flhF; flagellar biosynthesis protein FlhF"
				}
				]
			},
			{
				"name":"03037 Cilium and associated proteins"
			},
			{
				"name":"04812 Cytoskeleton proteins [BR:scc04812]",
				"children":[
				{
					"name":"Spico_0034 Tubulin\/FtsZ GTPase\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_0648 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_0649 cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"Spico_0746 Cobyrinic acid ac-diamide synthase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Spico_1863 chromosome segregation ATPase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Spico_1862 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				}
				]
			},
			{
				"name":"04147 Exosome [BR:scc04147]",
				"children":[
				{
					"name":"Spico_1820 Chaperone protein htpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Spico_1607 fructose-bisphosphate aldolase\tK01623 ALDO; fructose-bisphosphate aldolase, class I [EC:4.1.2.13]"
				},
				{
					"name":"Spico_1187 enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Spico_0471 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Spico_0087 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0472 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Spico_0349 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Spico_1861 Peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"Spico_1179 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Spico_0212 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Spico_1678 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Spico_1786 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Spico_0448 IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"Spico_1718 translation elongation factor 1A (EF-1A\/EF-Tu)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Spico_1285 histidine triad (HIT) protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"Spico_1643 L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"Spico_0277 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0884 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0899 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0978 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Spico_0727 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"Spico_0625 adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"Spico_1052 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Spico_0711 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Spico_0365 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Spico_0431 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_1232 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Spico_1557 glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Spico_1782 L-glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Spico_1767 IMP cyclohydrolase; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Spico_1652 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Spico_0473 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Spico_0424 phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				}
				]
			},
			{
				"name":"02048 Prokaryotic defense system [BR:scc02048]",
				"children":[
				{
					"name":"Spico_1131 CRISPR-associated protein, Cas1 family\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"Spico_1155 CRISPR-associated protein, Cas1 family\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"Spico_1132 CRISPR-associated protein, Cas2 family\tK09951 cas2; CRISPR-associated protein Cas2"
				},
				{
					"name":"Spico_1125 CRISPR-associated helicase Cas3\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]"
				},
				{
					"name":"Spico_1154 CRISPR-associated helicase Cas3 family\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]"
				},
				{
					"name":"Spico_1126 CRISPR-associated protein, Cse1 family\tK19123 casA; CRISPR system Cascade subunit CasA"
				},
				{
					"name":"Spico_1127 CRISPR-associated protein, Cse2 family\tK19046 casB; CRISPR system Cascade subunit CasB"
				},
				{
					"name":"Spico_1129 CRISPR-associated protein, Cse4 family\tK19124 casC; CRISPR system Cascade subunit CasC"
				},
				{
					"name":"Spico_1130 CRISPR-associated protein Cas5 family\tK19125 casD; CRISPR system Cascade subunit CasD"
				},
				{
					"name":"Spico_1128 CRISPR-associated protein, Cse3 family\tK19126 casE; CRISPR system Cascade subunit CasE"
				},
				{
					"name":"Spico_1153 CRISPR-associated protein, Csy1 family\tK19127 csy1; CRISPR-associated protein Csy1"
				},
				{
					"name":"Spico_1152 CRISPR-associated protein, Csy2 family\tK19128 csy2; CRISPR-associated protein Csy2"
				},
				{
					"name":"Spico_1151 CRISPR-associated protein, Csy3 family\tK19129 csy3; CRISPR-associated protein Csy3"
				},
				{
					"name":"Spico_1150 CRISPR-associated protein, Csy4 family\tK19130 csy4; CRISPR-associated endonuclease Csy4 [EC:3.1.-.-]"
				},
				{
					"name":"Spico_0553 Type II site-specific deoxyribonuclease\tK01155 E3.1.21.4; type II restriction enzyme [EC:3.1.21.4]"
				},
				{
					"name":"Spico_0552 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"Spico_0185 addiction module toxin, RelE\/StbE family\tK06218 relE; mRNA interferase RelE\/StbE"
				},
				{
					"name":"Spico_0193 addiction module toxin, RelE\/StbE family\tK06218 relE; mRNA interferase RelE\/StbE"
				},
				{
					"name":"Spico_0195 hypothetical protein\tK19165 phd; antitoxin Phd"
				},
				{
					"name":"Spico_1160 hypothetical protein\tK19165 phd; antitoxin Phd"
				},
				{
					"name":"Spico_0034 Tubulin\/FtsZ GTPase\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_0648 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Spico_1817 DNA topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Spico_1818 DNA topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Spico_0982 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Spico_0525 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"04030 G protein-coupled receptors"
			},
			{
				"name":"04050 Cytokine receptors"
			},
			{
				"name":"04054 Pattern recognition receptors"
			},
			{
				"name":"03310 Nuclear receptors"
			},
			{
				"name":"04040 Ion channels"
			},
			{
				"name":"04031 GTP-binding proteins"
			},
			{
				"name":"04052 Cytokines and neuropeptides"
			},
			{
				"name":"04515 Cell adhesion molecules"
			},
			{
				"name":"04090 CD molecules"
			},
			{
				"name":"01504 Antimicrobial resistance genes [BR:scc01504]",
				"children":[
				{
					"name":"Spico_0369 major facilitator superfamily MFS_1\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				}
				]
			},
			{
				"name":"00535 Proteoglycans"
			},
			{
				"name":"00536 Glycosaminoglycan binding proteins"
			},
			{
				"name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:scc00537]",
				"children":[
				{
					"name":"Spico_0158 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Spico_1179 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				}
				]
			},
			{
				"name":"04091 Lectins"
			},
			{
				"name":"04990 Domain-containing proteins not elsewhere classified"
			}
			]
		},
		{
			"name":"09185 Viral protein families",
			"children":[
			{
				"name":"03200 Viral proteins"
			},
			{
				"name":"03210 Viral fusion proteins"
			}
			]
		},
		{
			"name":"09184 RNA family",
			"children":[
			{
				"name":"03100 Non-coding RNAs [BR:scc03100]",
				"children":[
				{
					"name":"Spico_R0001 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0024 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0030 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0049 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Spico_R0034 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0038 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0047 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0056 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Spico_R0042 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"Spico_R0007 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Spico_R0048 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Spico_R0020 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Spico_R0043 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Spico_R0019 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Spico_R0026 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Spico_R0006 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0014 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0037 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Spico_R0033 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"Spico_R0003 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Spico_R0008 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0036 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0039 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0050 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Spico_R0027 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Spico_R0035 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Spico_R0012 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0046 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0051 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Spico_R0045 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"Spico_R0009 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0032 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0040 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Spico_R0054 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0055 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0057 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0058 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Spico_R0015 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0021 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0053 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Spico_R0052 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"Spico_R0018 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"Spico_R0010 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_R0011 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_R0013 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Spico_R0002 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0025 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0031 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Spico_R0004 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0023 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0029 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Spico_R0005 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0022 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0028 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Spico_R0017 RNA component of RNaseP\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"Spico_R0059 RNA component of signal recognition particle\tK01983 ffs; signal recognition particle 4.5S RNA"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"09190 Not Included in Pathway or Brite",
		"children":[
		{
			"name":"09191 Unclassified: metabolism",
			"children":[
			{
				"name":"99980 Enzymes with EC numbers",
				"children":[
				{
					"name":"Spico_1845 Gluconate 5-dehydrogenase\tK00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69]"
				},
				{
					"name":"Spico_1247 NADP-dependent oxidoreductase domain protein\tK19265 gpr; L-glyceraldehyde 3-phosphate reductase [EC:1.1.1.-]"
				},
				{
					"name":"Spico_1519 Alcohol dehydrogenase\tK19955 adh2; alcohol dehydrogenase [EC:1.1.1.-]"
				},
				{
					"name":"Spico_1220 NADPH dehydrogenase\tK00354 E1.6.99.1; NADPH2 dehydrogenase [EC:1.6.99.1]"
				},
				{
					"name":"Spico_1221 Peptide methionine sulfoxide reductase msrA\tK12267 msrAB; peptide methionine sulfoxide reductase msrA\/msrB [EC:1.8.4.11 1.8.4.12]"
				},
				{
					"name":"Spico_1755 Radical SAM domain protein\tK28783 E1.8.98.7; cysteine-type anaerobic sulfatase-maturating enzyme [EC:1.8.98.7]"
				},
				{
					"name":"Spico_1286 alkyl hydroperoxide reductase\/Thiol specific antioxidant\/Mal allergen\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"Spico_1570 thiol peroxidase (atypical 2-Cys peroxiredoxin)\tK11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"Spico_0663 peroxiredoxin\tK24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]"
				},
				{
					"name":"Spico_0354 hydrogenase, Fe-only\tK18332 hndD; NADP-reducing hydrogenase subunit HndD [EC:1.12.1.3]"
				},
				{
					"name":"Spico_1118 sulfide dehydrogenase (flavoprotein) subunit SudB\tK00528 fpr; ferredoxin\/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]"
				},
				{
					"name":"Spico_0845 anaerobic ribonucleoside-triphosphate reductase activating protein\tK04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]"
				},
				{
					"name":"Spico_0115 glycyl-radical enzyme activating protein family\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"Spico_1549 pyruvate formate-lyase activating enzyme\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"Spico_1057 Radical SAM domain protein\tK04070 pflX; putative pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"Spico_0104 glycyl-radical enzyme activating protein family\tK20037 cutD; choline trimethylamine-lyase activating enzyme [EC:1.97.1.-]"
				},
				{
					"name":"Spico_1236 Apolipoprotein N-acyltransferase\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]"
				},
				{
					"name":"Spico_0395 hypothetical protein\tK27956 lnb; lipoprotein N-acyltransferase [EC:2.3.1.-]"
				},
				{
					"name":"Spico_0497 Sucrose phosphorylase\tK22597 E2.4.1.352; glucosylglycerate phosphorylase [EC:2.4.1.352]"
				},
				{
					"name":"Spico_1834 Prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]"
				},
				{
					"name":"Spico_0945 ApbE family lipoprotein\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]"
				},
				{
					"name":"Spico_1456 Conserved hypothetical protein CHP00159\tK18672 dacA; diadenylate cyclase [EC:2.7.7.85]"
				},
				{
					"name":"Spico_1588 Hpr(Ser) kinase\/phosphatase\tK06023 hprK; HPr kinase\/phosphorylase [EC:2.7.11.- 2.7.4.-]"
				},
				{
					"name":"Spico_0983 hypothetical protein\tK03928 yvaK; carboxylesterase [EC:3.1.1.1]"
				},
				{
					"name":"Spico_0136 Appr-1-p processing domain protein\tK23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]"
				},
				{
					"name":"Spico_1568 thioesterase superfamily protein\tK18700 flK; fluoroacetyl-CoA thioesterase [EC:3.1.2.29]"
				},
				{
					"name":"Spico_0776 4-hydroxybenzoyl-CoA thioesterase\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"Spico_0468 metal dependent phosphohydrolase\tK07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]"
				},
				{
					"name":"Spico_0924 hydrolase, TatD family\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"Spico_1242 hydrolase, TatD family\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"Spico_0713 Alpha-glucuronidase\tK01235 aguA; alpha-glucuronidase [EC:3.2.1.139]"
				},
				{
					"name":"Spico_0059 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Spico_0866 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Spico_1283 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Spico_1735 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Spico_0498 hypothetical protein\tK27494 exoMA1; D-arabinan exo alpha-(1,3)\/(1,5)-arabinofuranosidase (non-reducing end) [EC:3.2.1.225]"
				},
				{
					"name":"Spico_1448 peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"Spico_1483 glycoside hydrolase family 57\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]"
				},
				{
					"name":"Spico_0865 endoribonuclease L-PSP\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"Spico_0938 YjeF-related protein\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]"
				},
				{
					"name":"Spico_0400 protein of unknown function DUF111\tK09121 larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]"
				},
				{
					"name":"Spico_1655 L-rhamnose 1-epimerase\tK03534 rhaM; L-rhamnose mutarotase [EC:5.1.3.32]"
				},
				{
					"name":"Spico_0532 electron transport complex, RnfABCDGE type, D subunit\tK03614 rnfD; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit D [EC:7.1.1.11 7.2.1.2]"
				},
				{
					"name":"Spico_0531 electron transport complex, RnfABCDGE type, C subunit\tK03615 rnfC; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit C [EC:7.1.1.11 7.2.1.2]"
				},
				{
					"name":"Spico_1637 calcium-translocating P-type ATPase, PMCA-type\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]"
				},
				{
					"name":"Spico_0672 heavy metal translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				},
				{
					"name":"Spico_1377 magnesium-translocating P-type ATPase\tK01531 mgtA; P-type Mg2+ transporter [EC:7.2.2.14]"
				}
				]
			},
			{
				"name":"99981 Carbohydrate metabolism",
				"children":[
				{
					"name":"Spico_1087 CBS domain containing membrane protein\tK04767 acuB; acetoin utilization protein AcuB"
				}
				]
			},
			{
				"name":"99982 Energy metabolism",
				"children":[
				{
					"name":"Spico_0533 FMN-binding domain protein\tK03612 rnfG; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit G"
				},
				{
					"name":"Spico_0534 RnfA-Nqr electron transport subunit\tK03613 rnfE; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit E"
				},
				{
					"name":"Spico_0535 electron transport complex, RnfABCDGE type, A subunit\tK03617 rnfA; H+\/Na+-translocating ferredoxin:NAD+ oxidoreductase subunit A"
				},
				{
					"name":"Spico_1760 SUF system FeS assembly protein, NifU family\tK04488 iscU; nitrogen fixation protein NifU and related proteins"
				},
				{
					"name":"Spico_0463 flavodoxin\tK03839 fldA; flavodoxin I"
				}
				]
			},
			{
				"name":"99983 Lipid metabolism"
			},
			{
				"name":"99984 Nucleotide metabolism"
			},
			{
				"name":"99985 Amino acid metabolism",
				"children":[
				{
					"name":"Spico_0449 protein of unknown function UPF0001\tK06997 yggS; PLP dependent protein"
				}
				]
			},
			{
				"name":"99986 Glycan metabolism",
				"children":[
				{
					"name":"Spico_0303 hypothetical protein\tK07027 K07027; glycosyltransferase 2 family protein"
				}
				]
			},
			{
				"name":"99987 Cofactor metabolism"
			},
			{
				"name":"99988 Secondary metabolism",
				"children":[
				{
					"name":"Spico_1553 NADPH-dependent FMN reductase\tK19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)"
				}
				]
			},
			{
				"name":"99999 Others"
			}
			]
		},
		{
			"name":"09192 Unclassified: genetic information processing",
			"children":[
			{
				"name":"99973 Transcription"
			},
			{
				"name":"99974 Translation",
				"children":[
				{
					"name":"Spico_0752 beta-lactamase domain protein\tK07576 K07576; metallo-beta-lactamase family protein"
				}
				]
			},
			{
				"name":"99975 Protein processing",
				"children":[
				{
					"name":"Spico_0792 Trigger factor\tK03545 tig; trigger factor"
				},
				{
					"name":"Spico_0578 SsrA-binding protein\tK03664 smpB; SsrA-binding protein"
				},
				{
					"name":"Spico_0664 magnesium chelatase ChlI subunit\tK07391 comM; magnesium chelatase family protein"
				}
				]
			},
			{
				"name":"99976 Replication and repair",
				"children":[
				{
					"name":"Spico_0765 Resolvase domain protein\tK07450 K07450; putative resolvase"
				},
				{
					"name":"Spico_1838 Resolvase domain protein\tK07450 K07450; putative resolvase"
				},
				{
					"name":"Spico_1418 DNA repair protein RadC\tK03630 radC; DNA repair protein RadC"
				},
				{
					"name":"Spico_0228 RmuC-domain protein\tK09760 rmuC; DNA recombination protein RmuC"
				},
				{
					"name":"Spico_0515 UPF0102 protein yraN\tK07460 yraN; putative endonuclease"
				},
				{
					"name":"Spico_0646 hypothetical protein\tK04096 smf; DNA processing protein"
				},
				{
					"name":"Spico_1104 SMF family protein\tK04096 smf; DNA processing protein"
				},
				{
					"name":"Spico_0791 Recombination protein MgsA\tK07478 ycaJ; putative ATPase"
				},
				{
					"name":"Spico_0764 transposase, IS605 OrfB family\tK07496 K07496; putative transposase"
				},
				{
					"name":"Spico_1837 transposase, IS605 OrfB family\tK07496 K07496; putative transposase"
				}
				]
			},
			{
				"name":"99979 Viral proteins"
			},
			{
				"name":"99998 Others",
				"children":[
				{
					"name":"Spico_0140 phage shock protein A, PspA\tK03969 pspA; phage shock protein A"
				},
				{
					"name":"Spico_0143 phage shock protein A, PspA\tK03969 pspA; phage shock protein A"
				}
				]
			}
			]
		},
		{
			"name":"09193 Unclassified: signaling and cellular processes",
			"children":[
			{
				"name":"99977 Transport",
				"children":[
				{
					"name":"Spico_1067 major facilitator superfamily MFS_1\tK03292 TC.GPH; glycoside\/pentoside\/hexuronide:cation symporter, GPH family"
				},
				{
					"name":"Spico_1747 citrate\/H+ symporter, CitMHS family\tK03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family"
				},
				{
					"name":"Spico_0164 phosphate transporter\tK03306 TC.PIT; inorganic phosphate transporter, PiT family"
				},
				{
					"name":"Spico_1527 branched-chain amino acid transport system II carrier protein\tK03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family"
				},
				{
					"name":"Spico_0049 Bile acid:sodium symporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family"
				}
				]
			},
			{
				"name":"99978 Cell growth",
				"children":[
				{
					"name":"Spico_0008 single-stranded nucleic acid binding R3H domain-containing protein\tK06346 jag; spoIIIJ-associated protein"
				},
				{
					"name":"Spico_0975 septation protein spoVG\tK06412 spoVG; stage V sporulation protein G"
				}
				]
			},
			{
				"name":"99993 Cell motility"
			},
			{
				"name":"99995 Signaling proteins",
				"children":[
				{
					"name":"Spico_0749 GTP-binding protein TypA\tK06207 typA; GTP-binding protein"
				},
				{
					"name":"Spico_1543 ACT domain-containing protein\tK07166 K07166; ACT domain-containing protein"
				},
				{
					"name":"Spico_0467 PhoH family protein\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins"
				}
				]
			},
			{
				"name":"99992 Structural proteins",
				"children":[
				{
					"name":"Spico_0287 protein of unknown function UPF0118\tK11744 tqsA; AI-2 transport protein TqsA"
				}
				]
			},
			{
				"name":"99994 Others",
				"children":[
				{
					"name":"Spico_0439 phosphate uptake regulator, PhoU\tK02039 phoU; phosphate transport system protein"
				},
				{
					"name":"Spico_1808 CutC family protein\tK06201 cutC; copper homeostasis protein"
				}
				]
			}
			]
		},
		{
			"name":"09194 Poorly characterized",
			"children":[
			{
				"name":"99996 General function prediction only",
				"children":[
				{
					"name":"Spico_0637 Colicin V production protein\tK03558 cvpA; membrane protein required for colicin V production"
				},
				{
					"name":"Spico_0297 Patatin\tK07001 K07001; NTE family protein"
				},
				{
					"name":"Spico_1446 Patatin\tK07001 K07001; NTE family protein"
				},
				{
					"name":"Spico_1683 Haloacid dehalogenase domain protein hydrolase\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"Spico_1763 Iron-regulated ABC transporter membrane component SufB\tK09014 sufB; Fe-S cluster assembly protein SufB"
				},
				{
					"name":"Spico_1762 SufBD protein\tK09015 sufD; Fe-S cluster assembly protein SufD"
				},
				{
					"name":"Spico_1513 aryldialkylphosphatase\tK07048 PTER; phosphotriesterase-related protein"
				},
				{
					"name":"Spico_1223 ribonuclease BN\tK07058 K07058; membrane protein"
				},
				{
					"name":"Spico_0256 protein PhnB\tK04750 phnB; PhnB protein"
				},
				{
					"name":"Spico_0205 LemA family protein\tK03744 lemA; LemA protein"
				},
				{
					"name":"Spico_1800 SlyX family protein\tK03745 slyX; SlyX protein"
				}
				]
			},
			{
				"name":"99997 Function unknown",
				"children":[
				{
					"name":"Spico_0118 Ankyrin\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"Spico_0408 metal dependent phosphohydrolase\tK06885 K06885; uncharacterized protein"
				},
				{
					"name":"Spico_1634 alpha\/beta hydrolase fold protein\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"Spico_0789 protein of unknown function UPF0005\tK06890 K06890; uncharacterized protein"
				},
				{
					"name":"Spico_0620 protein of unknown function UPF0153\tK06940 K06940; uncharacterized protein"
				},
				{
					"name":"Spico_1020 protein of unknown function UPF0153\tK06940 K06940; uncharacterized protein"
				},
				{
					"name":"Spico_0511 RNA-binding protein (KH domain)\tK06960 K06960; uncharacterized protein"
				},
				{
					"name":"Spico_1034 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein\tK07005 K07005; uncharacterized protein"
				},
				{
					"name":"Spico_1484 amidohydrolase 2\tK07045 K07045; uncharacterized protein"
				},
				{
					"name":"Spico_1093 Nucleotidyltransferase\tK07074 K07074; uncharacterized protein"
				},
				{
					"name":"Spico_1528 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Spico_1756 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Spico_0373 phosphodiesterase, MJ0936 family\tK07095 K07095; uncharacterized protein"
				},
				{
					"name":"Spico_1225 metallophosphoesterase\tK07095 K07095; uncharacterized protein"
				},
				{
					"name":"Spico_0480 phosphoribosyl transferase domain protein\tK07101 K07101; uncharacterized protein"
				},
				{
					"name":"Spico_1295 phosphoribosyltransferase\tK07101 K07101; uncharacterized protein"
				},
				{
					"name":"Spico_1746 membrane protein AbrB duplication\tK07120 K07120; uncharacterized protein"
				},
				{
					"name":"Spico_0267 hypothetical protein\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Spico_0974 uncharacterized Fe-S center protein\tK07138 K07138; uncharacterized protein"
				},
				{
					"name":"Spico_1445 Radical SAM domain protein\tK07139 K07139; uncharacterized protein"
				},
				{
					"name":"Spico_0235 protein of unknown function DUF554\tK07150 K07150; uncharacterized protein"
				},
				{
					"name":"Spico_0617 protein of unknown function DUF164\tK07164 K07164; uncharacterized protein"
				},
				{
					"name":"Spico_0966 UPF0161 protein yidD\tK08998 K08998; uncharacterized protein"
				},
				{
					"name":"Spico_1544 UPF0210 protein\tK09157 K09157; uncharacterized protein"
				},
				{
					"name":"Spico_1230 hypothetical protein\tK09160 K09160; uncharacterized protein"
				},
				{
					"name":"Spico_0947 metal dependent phosphohydrolase\tK09163 K09163; uncharacterized protein"
				},
				{
					"name":"Spico_0067 protein of unknown function DUF985\tK09705 K09705; uncharacterized protein"
				},
				{
					"name":"Spico_0888 UPF0178 protein yaiI\tK09768 K09768; uncharacterized protein"
				},
				{
					"name":"Spico_0735 acid phosphatase\/vanadium-dependent haloperoxidase related protein\tK09775 K09775; uncharacterized protein"
				},
				{
					"name":"Spico_0368 protein of unknown function DUF454\tK09790 K09790; uncharacterized protein"
				},
				{
					"name":"Spico_1306 protein of unknown function DUF541\tK09807 K09807; uncharacterized protein"
				},
				{
					"name":"Spico_1390 protein of unknown function DUF1006\tK09927 K09927; uncharacterized protein"
				},
				{
					"name":"Spico_1632 putative ABC transporter permease\tK01163 K01163; uncharacterized protein"
				},
				{
					"name":"Spico_0163 putative phosphate transport regulator\tK07220 K07220; uncharacterized protein"
				}
				]
			}
			]
		}
		]
	}
	]
}