{
	"name":"scy01008",
	"children":[
	{
		"name":"Polyketide synthase (PKS)",
		"children":[
		{
			"name":"Modular type I PKS",
			"children":[
			{
				"name":"cis-AT PKS",
				"children":[
				{
					"name":"Erythronolide PKS"
				},
				{
					"name":"Oleandomycin synthase"
				},
				{
					"name":"Pikromycin PKS"
				},
				{
					"name":"Avermectin PKS"
				},
				{
					"name":"Tylactone synthase"
				},
				{
					"name":"Protomycinolide IV synthase"
				},
				{
					"name":"Niddamycin PKS"
				},
				{
					"name":"Rapamycin PKS"
				},
				{
					"name":"Immunomycin PKS"
				},
				{
					"name":"Ansamitocin PKS"
				},
				{
					"name":"Rifamycin PKS"
				},
				{
					"name":"Polyene macrolide PKS"
				},
				{
					"name":"Pimaricinolide synthase"
				},
				{
					"name":"Candicidin PKS"
				},
				{
					"name":"Soraphen PKS"
				},
				{
					"name":"Stigmatellin PKS"
				},
				{
					"name":"Mycolactone PKS"
				},
				{
					"name":"Coelimycin PKS"
				},
				{
					"name":"Aureothin PKS"
				},
				{
					"name":"Spectinabilin PKS"
				},
				{
					"name":"Phthiocerol \/ Phenolphthiocerol PKS"
				}
				]
			},
			{
				"name":"trans-AT PKS",
				"children":[
				{
					"name":"Bacillanene hybrid PKS-NRPS",
					"children":[
					{
						"name":"SCATT_35750 putative acyltransferase\tK15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains"
					}
					]
				},
				{
					"name":"Macrolactin PKS",
					"children":[
					{
						"name":"SCATT_35750 putative acyltransferase\tK15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains"
					}
					]
				},
				{
					"name":"Difficidin PKS",
					"children":[
					{
						"name":"SCATT_35750 putative acyltransferase\tK15329 pksE; trans-AT polyketide synthase, acyltransferase and oxidoreductase domains"
					}
					]
				},
				{
					"name":"Rhizoxin hybrid PKS-NRPS"
				},
				{
					"name":"Albicidin synthase, hybrid PKS-NRPS"
				}
				]
			}
			]
		},
		{
			"name":"Iterative type I PKS",
			"children":[
			{
				"name":"Fungal nonreducing PKS (NR-PKS)"
			},
			{
				"name":"Fungal partially reducing PKS (PR-PKS)"
			},
			{
				"name":"Fungal highly reducing PKS (HR-PKS)"
			},
			{
				"name":"Fungal hybrid type",
				"children":[
				{
					"name":"Zearalenone synthase"
				}
				]
			},
			{
				"name":"Bacterial type"
			}
			]
		},
		{
			"name":"Type II PKS",
			"children":[
			{
				"name":"C9-C14 cyclized polyketide type",
				"children":[
				{
					"name":"Spore pigment PKS"
				}
				]
			},
			{
				"name":"C7-C14 cyclized polyketide type",
				"children":[
				{
					"name":"Octaketide PKS"
				},
				{
					"name":"Nonaketide PKS"
				},
				{
					"name":"Decaketide PKS"
				}
				]
			}
			]
		},
		{
			"name":"Type III PKS",
			"children":[
			{
				"name":"Plant type"
			},
			{
				"name":"Fungal type"
			},
			{
				"name":"Bacterial type",
				"children":[
				{
					"name":"SCATT_50210 Type III polyketide synthase RppA\tK19580 rppA; 1,3,6,8-tetrahydroxynaphthalene synthase [EC:2.3.1.233]"
				}
				]
			}
			]
		},
		{
			"name":"PKS-NRPS hybrid",
			"children":[
			{
				"name":"Bacterial type (modular)",
				"children":[
				{
					"name":"Myxalamid hybrid PKS-NRPS"
				},
				{
					"name":"Coronatine hybrid PKS-NRPS"
				},
				{
					"name":"Microcystin synthetase"
				},
				{
					"name":"Epothilone synthetase"
				},
				{
					"name":"Bleomycin synthetase"
				},
				{
					"name":"Colibactin synthetase"
				},
				{
					"name":"Myxothiazol hybrid PKS-NRPS"
				}
				]
			},
			{
				"name":"Fungal type (trans-ER, iterative)",
				"children":[
				{
					"name":"Aspyridone synthetase"
				}
				]
			},
			{
				"name":"Fungal type (iterative)"
			}
			]
		}
		]
	},
	{
		"name":"Nonribosomal peptide synthetase (NRPS)",
		"children":[
		{
			"name":"Linear NRPS",
			"children":[
			{
				"name":"Emericellamide synthetase"
			},
			{
				"name":"Cyanopeptolin synthetase"
			},
			{
				"name":"ACV synthetase",
				"children":[
				{
					"name":"SCATT_56840 N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase\tK12743 PCBAB; N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase [EC:6.3.2.26]"
				}
				]
			},
			{
				"name":"Bacitracin synthetase"
			},
			{
				"name":"Viomycin synthetase"
			},
			{
				"name":"Pristinamycin I synthetase"
			},
			{
				"name":"Tyrocidine synthetase"
			},
			{
				"name":"Surfactin family lipopeptide synthetase"
			},
			{
				"name":"Iturin family lipopeptide synthetase"
			},
			{
				"name":"Fengycin family lipopeptide synthetase"
			},
			{
				"name":"Arthrofactin type cyclic lipopeptide synthetase"
			},
			{
				"name":"Vancomycin synthetase"
			},
			{
				"name":"Nocardicin synthetase",
				"children":[
				{
					"name":"SCATT_26740 putative MbtH-like protein\tK05375 mbtH; MbtH protein"
				},
				{
					"name":"SCATT_p11170 MbtH domain protein\tK05375 mbtH; MbtH protein"
				},
				{
					"name":"SCATT_p15650 MbtH domain protein\tK05375 mbtH; MbtH protein"
				}
				]
			},
			{
				"name":"Bialaphos synthetase"
			},
			{
				"name":"L-2-amino-4-methoxy-trans-3-butenoic acid synthetase"
			},
			{
				"name":"Anabaenopeptin synthetase"
			},
			{
				"name":"Linear gramicidin synthetase"
			}
			]
		},
		{
			"name":"Iterative NRPS",
			"children":[
			{
				"name":"Enterobactin synthetase",
				"children":[
				{
					"name":"SCATT_50760 putative Sfp type phosphopantetheinyl transferase\tK02362 entD; enterobactin synthetase component D \/ holo-[acyl-carrier protein] synthase [EC:6.3.2.14 2.7.8.7]"
				}
				]
			},
			{
				"name":"Bacillibactin synthetase"
			},
			{
				"name":"Gramicidin synthetase"
			}
			]
		},
		{
			"name":"Nonlinear NRPS",
			"children":[
			{
				"name":"Yersiniabactin synthetase"
			},
			{
				"name":"Pyochelin synthetase"
			},
			{
				"name":"Mycobactin synthetase"
			},
			{
				"name":"Vibriobactin synthetase"
			},
			{
				"name":"Myxochelin synthetase"
			},
			{
				"name":"Petrobacin synthetase"
			},
			{
				"name":"Syringomycin synthetase"
			},
			{
				"name":"Vanchrobactin synthetase"
			},
			{
				"name":"Isonitrile lipopeptide synthase"
			}
			]
		}
		]
	},
	{
		"name":"Polyketide tailoring proteins",
		"children":[
		{
			"name":"Hydrolase"
		},
		{
			"name":"Ketoreductase",
			"children":[
			{
				"name":"SCATT_p09860 3-hydroxyacyl-CoA dehydrogenase\tK05556 actVI1; ketoreductase RED1 [EC:1.1.1.-]"
			}
			]
		},
		{
			"name":"Oxygenase",
			"children":[
			{
				"name":"SCATT_01740 epoxide hydrolase 1\tK21159 sgcF; epoxide hydrolase"
			}
			]
		},
		{
			"name":"Methylase"
		},
		{
			"name":"Glycosyltransferase"
		},
		{
			"name":"Halogenase",
			"children":[
			{
				"name":"SCATT_55980 halogenase\tK14257 ctcP; tetracycline 7-halogenase \/ FADH2 O2-dependent halogenase [EC:1.14.19.49 1.14.19.-]"
			}
			]
		},
		{
			"name":"beta-Branched incorporating proteins"
		},
		{
			"name":"Others"
		}
		]
	},
	{
		"name":"Nonribosomal peptide tailoring proteins",
		"children":[
		{
			"name":"Reductase"
		},
		{
			"name":"Thioesterase"
		},
		{
			"name":"Oxygenase"
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"SCATT_p01310 rifampin glycosyltransferase\tK16444 gtfB; vancomycin aglycone glucosyltransferase [EC:2.4.1.310]"
			}
			]
		},
		{
			"name":"Aminotransferase"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"SCATT_56830 isopenicillin N synthase\tK04126 PCBC; isopenicillin-N synthase [EC:1.21.3.1]"
			},
			{
				"name":"SCATT_56860 isopenicillin N epimerase\tK04127 cefD; isopenicillin-N epimerase [EC:5.1.1.17]"
			},
			{
				"name":"SCATT_56870 deacetoxycephalosporin C synthase\tK12744 cefE; deacetoxycephalosporin-C synthase [EC:1.14.20.1]"
			},
			{
				"name":"SCATT_56810 deacetylcephalosporin C synthase\tK12745 cefF; deacetoxycephalosporin-C hydroxylase [EC:1.14.11.26]"
			},
			{
				"name":"SCATT_56820 3'-hydroxymethylcephem-O-carbamoyltransferase\tK04128 cmcH; hydroxymethyl cephem carbamoyltransferase [EC:2.1.3.7]"
			},
			{
				"name":"SCATT_56790 hydroxylase\tK18062 cmcI; cephamycin C biosynthesis protein"
			},
			{
				"name":"SCATT_56800 hypothetical protein\tK18063 cmcJ; cephamycin C biosynthesis protein"
			},
			{
				"name":"SCATT_26630 aspartate racemase subfamily\tK01779 racD; aspartate racemase [EC:5.1.1.13]"
			}
			]
		}
		]
	}
	]
}