{
	"name":"sdg03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"SDE12394_04580 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"SDE12394_07035 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family"
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"SDE12394_08810 Lactose phosphotransferase system repressor\tK02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor"
				},
				{
					"name":"SDE12394_04360 Fructose repressor\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"SDE12394_09105 CBS domain protein\tK23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"SDE12394_02750 Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"SDE12394_06795 LacI family transcriptional repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"SDE12394_07985 putative ribose transport operon repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"SDE12394_09440 LacI family transcription regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"SDE12394_03455 LacI family transcription regulator\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				},
				{
					"name":"SDE12394_09285 putative sucrose operon repressor\tK03484 scrR; LacI family transcriptional regulator, sucrose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"SDE12394_08295 putative transcription regulator\tK02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor"
				},
				{
					"name":"SDE12394_10445 GntR family regulatory protein\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"SDE12394_03660 Transcriptional regulator, GntR family protein\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"SDE12394_05345 putative transcription regulator\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"SDE12394_03675 transcriptional regulator GntR family protein\tK03710 K03710; GntR family transcriptional regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family"
			},
			{
				"name":"Lrp\/AsnC family"
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family"
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"SDE12394_09595 Putative transcriptional regulator\tK03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"SDE12394_10100 ferric uptake regulation protein\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"SDE12394_08050 Transcriptional regulator, CrP\/Fnr family protein\tK21828 arcR; CRP\/FNR family transcriptional regulator, arginine deiminase pathway regulator"
				},
				{
					"name":"SDE12394_01105 Crp family regulatory protein\tK16326 yeiL; CRP\/FNR family transcriptional regulator, putaive post-exponential-phase nitrogen-starvation regulator"
				}
				]
			},
			{
				"name":"Rrf2 family"
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"SDE12394_04785 cadmium efflux system accessory protein\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"SDE12394_10630 Putative cadmium efflux system accessory\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"SDE12394_06515 hypothetical protein\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"SDE12394_10695 hypothetical protein\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"SDE12394_02370 iron-dependent repressor\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"SDE12394_07355 biotin--protein ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"SDE12394_00190 transcriptional regulator\tK20342 comR; HTH-type transcriptional regulator, regulator for ComX"
				},
				{
					"name":"SDE12394_02655 Transcriptional regulator\tK20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator"
				},
				{
					"name":"SDE12394_09645 pur operon repressor\tK09685 purR; HTH-type transcriptional regulator, purine operon repressor"
				},
				{
					"name":"SDE12394_04965 redox-sensing transcriptional repressor Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"SDE12394_09135 transcriptional repressor CodY\tK03706 codY; transcriptional pleiotropic repressor"
				},
				{
					"name":"SDE12394_00755 transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"SDE12394_00550 DNA-binding protein\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"SDE12394_01235 Cro\/CI family transcriptional regulator\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"SDE12394_07440 Transcriptional regulator, Cro\/CI family protein\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"SDE12394_10730 RelB protein\tK18918 relB; RHH-type transcriptional regulator, rel operon repressor \/ antitoxin RelB"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"SDE12394_02940 BigG family transcription antiterminator\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				},
				{
					"name":"SDE12394_10140 Transcription antiterminator, BglG family protein\tK03493 bglG1; transcriptional antiterminator"
				},
				{
					"name":"SDE12394_06920 PTS system, mannitol (cryptic)-specific IIA component\tK03491 licR; probable licABCH operon transcriptional regulator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"SDE12394_11020 chromosome partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"SDE12394_07725 Putative repressor protein\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"SDE12394_08055 Putative arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"SDE12394_10570 putative arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"SDE12394_09050 hrcA; heat-inducible transcription repressor\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"SDE12394_10340 transcriptional regulator ctsR\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"SDE12394_04265 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"SDE12394_01890 nrdR; transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"SDE12394_01485 putative competence protein (ComX1)\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"SDE12394_01705 putative competence protein (ComX1)\tK12296 comX1_2; competence protein ComX"
				}
				]
			}
			]
		}
		]
	}
	]
}