{
	"name":"sfi04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"SFUL_2698 Enolase 1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"SFUL_4894 Enolase 2\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"SFUL_1505 Glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"SFUL_154 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"SFUL_6554 Glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"SFUL_1504 PGK Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"SFUL_1559 Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"SFUL_5226 Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"SFUL_3526 PPIB Peptidyl-prolyl cis-trans isomerase B\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"SFUL_2657 Membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"SFUL_3412 Band 7 protein\tK07192 FLOT; flotillin"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"SFUL_4096 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4565 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_3291 Chaperone protein dnaK1\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"SFUL_1500 G6PI Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"SFUL_4923 Peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"SFUL_4577 Inosine-5'-monophosphatedehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"SFUL_4578 IMP dehydrogenase family protein\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"SFUL_4483 Elongation factor Tu 1\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"SFUL_845 Elongation factor Tu 2\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"SFUL_4928 AAA ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
			},
			{
				"name":"SFUL_2112 Diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells",
			"children":[
			{
				"name":"SFUL_4923 Peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			}
			]
		},
		{
			"name":"Exosomal proteins of hepatic cells",
			"children":[
			{
				"name":"SFUL_6372 Bile acid:sodium symporter\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"SFUL_1217 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_1705 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_2122 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_2932 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_334 O-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_6370 Long-chain-fatty-acid-CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"SFUL_4096 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4565 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_2685 Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_2933 Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_322 Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_5194 Thiolase FadA\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_6086 Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_6501 Acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"SFUL_2620 SAHH Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"SFUL_4509 KAD Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"SFUL_1025 Adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"SFUL_1086 ARLY Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"SFUL_1087 ASSY Argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"SFUL_3600 CysMet metabolism pyridoxal-phosphate-dependent protein\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
			},
			{
				"name":"SFUL_6247 Dihydropyrimidinase\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"SFUL_4385 Fumarylacetoacetase\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"SFUL_6041 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
			},
			{
				"name":"SFUL_2761 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
			},
			{
				"name":"SFUL_5235 1,4-alpha-glucan-branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"SFUL_1177 Glycerol kinase 1\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"SFUL_1764 glutamine synthetase I\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"SFUL_1776 Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"SFUL_1822 Glutamine synthetase catalytic region\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"SFUL_659 Glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"SFUL_1500 G6PI Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"SFUL_2991 Delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"SFUL_2523 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"SFUL_6363 pterin-4-alpha-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"SFUL_5369 D-3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"SFUL_4616 Bifunctional purine biosynthesis protein purH\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			},
			{
				"name":"SFUL_1333 Trypsin-1\tK01312 PRSS1_2_3; trypsin [EC:3.4.21.4]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"SFUL_1217 AMP-dependent synthetase and ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_1705 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_2122 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_2932 Acyl-CoA synthetase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_334 O-succinylbenzoate--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_6370 Long-chain-fatty-acid-CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"SFUL_1749 Dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"SFUL_611 Flavoprotein reductase\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"SFUL_6272 Flavoprotein reductase\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"SFUL_3354 Glu\/Leu\/Phe\/Val dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
			},
			{
				"name":"SFUL_1493 Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"SFUL_4577 Inosine-5'-monophosphatedehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"SFUL_4578 IMP dehydrogenase family protein\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"SFUL_3291 Chaperone protein dnaK1\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"SFUL_4096 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4565 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4483 Elongation factor Tu 1\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"SFUL_845 Elongation factor Tu 2\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"SFUL_4096 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4565 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_1500 G6PI Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"SFUL_4923 Peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
			},
			{
				"name":"SFUL_1493 Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"SFUL_3291 Chaperone protein dnaK1\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"SFUL_1503 Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"SFUL_4483 Elongation factor Tu 1\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"SFUL_845 Elongation factor Tu 2\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"SFUL_4096 60 kDa chaperonin 2\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_4565 60 kDa chaperonin 1\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"SFUL_1493 Glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"SFUL_4039 GPMA 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"SFUL_1503 Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"SFUL_4039 GPMA 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"SFUL_1503 Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}