{
	"name":"sft01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family"
		},
		{
			"name":"PKG family"
		},
		{
			"name":"PKC family [OT]"
		},
		{
			"name":"PKN family"
		},
		{
			"name":"AUR family [OT]"
		},
		{
			"name":"PDK1 family"
		},
		{
			"name":"AKT\/PKB family"
		},
		{
			"name":"SGK family [OT]"
		},
		{
			"name":"RSK family [OT]"
		},
		{
			"name":"NDR family"
		},
		{
			"name":"MAST family [OT]"
		},
		{
			"name":"YANK family"
		},
		{
			"name":"DMPK family [OT]"
		},
		{
			"name":"GRK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]"
		},
		{
			"name":"CAMK2 family"
		},
		{
			"name":"CAMKL family"
		},
		{
			"name":"DAPK family"
		},
		{
			"name":"DCAMKL family"
		},
		{
			"name":"MAPKAPK family [OT]"
		},
		{
			"name":"MLCK family"
		},
		{
			"name":"PHK family"
		},
		{
			"name":"PIM family [OT]"
		},
		{
			"name":"PKD family"
		},
		{
			"name":"PSK family"
		},
		{
			"name":"RAD53 family"
		},
		{
			"name":"Trio family [OT]"
		},
		{
			"name":"TSSK family"
		},
		{
			"name":"CDPK family"
		},
		{
			"name":"CASK family"
		},
		{
			"name":"Trbl family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]"
		},
		{
			"name":"TTBK family"
		},
		{
			"name":"VRK family"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family"
		},
		{
			"name":"MAPK family [OT]"
		},
		{
			"name":"GSK family [OT]"
		},
		{
			"name":"CLK family"
		},
		{
			"name":"CDKL family"
		},
		{
			"name":"DYRK family [OT]"
		},
		{
			"name":"RCK family [OT]"
		},
		{
			"name":"SRPK family [OT]"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family"
		},
		{
			"name":"STE20 family"
		},
		{
			"name":"STE11 family"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family"
		},
		{
			"name":"LISK family [OT]"
		},
		{
			"name":"LRRK family"
		},
		{
			"name":"MLK family"
		},
		{
			"name":"RAF family [OT]"
		},
		{
			"name":"RIPK family [OT]"
		},
		{
			"name":"Other"
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]"
		},
		{
			"name":"BUB family"
		},
		{
			"name":"Bud32 family"
		},
		{
			"name":"CAMKK family"
		},
		{
			"name":"CDC7 family"
		},
		{
			"name":"CK2 family"
		},
		{
			"name":"Haspin family"
		},
		{
			"name":"IKK family [OT]"
		},
		{
			"name":"IRE family"
		},
		{
			"name":"MOS family"
		},
		{
			"name":"NAK family [OT]"
		},
		{
			"name":"NEK family"
		},
		{
			"name":"NKF1 family"
		},
		{
			"name":"NKF2 family"
		},
		{
			"name":"NKF3 family"
		},
		{
			"name":"NKF4 family"
		},
		{
			"name":"NKF5 family"
		},
		{
			"name":"NRBP family"
		},
		{
			"name":"PEK family [OT]"
		},
		{
			"name":"PLK family [OT]"
		},
		{
			"name":"SCY1 family [OT]"
		},
		{
			"name":"Slob family"
		},
		{
			"name":"TBCK family"
		},
		{
			"name":"TLK family"
		},
		{
			"name":"TOPK family"
		},
		{
			"name":"TTK family"
		},
		{
			"name":"ULK family [OT]"
		},
		{
			"name":"VPS15 family"
		},
		{
			"name":"WEE family"
		},
		{
			"name":"Wnk family"
		},
		{
			"name":"ABC1 family"
		},
		{
			"name":"Alpha family [OT]"
		},
		{
			"name":"BCR family"
		},
		{
			"name":"BRD family [OT]"
		},
		{
			"name":"FAST family"
		},
		{
			"name":"G11 family"
		},
		{
			"name":"H11 family"
		},
		{
			"name":"PDHK family [OT]"
		},
		{
			"name":"PIKK family [OT]"
		},
		{
			"name":"RIO family [OT]"
		},
		{
			"name":"TAF1 family"
		},
		{
			"name":"TIF1 family [OT]"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial family"
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]"
		},
		{
			"name":"TGFBR2 family [OT]"
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]"
		},
		{
			"name":"INSR family [OT]"
		},
		{
			"name":"PDGFR family [OT]"
		},
		{
			"name":"FGFR family [OT]"
		},
		{
			"name":"VEGFR family [OT]"
		},
		{
			"name":"MET family"
		},
		{
			"name":"TRK family [OT]"
		},
		{
			"name":"EPH family [OT]"
		},
		{
			"name":"AXL family"
		},
		{
			"name":"ALK family"
		},
		{
			"name":"TIE family"
		},
		{
			"name":"ROR family"
		},
		{
			"name":"DDR family"
		},
		{
			"name":"RET family"
		},
		{
			"name":"ROS family"
		},
		{
			"name":"CCK family"
		},
		{
			"name":"RYK family"
		},
		{
			"name":"MUSK family"
		},
		{
			"name":"LMR family [OT]"
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family"
		},
		{
			"name":"ACK family"
		},
		{
			"name":"CSK family"
		},
		{
			"name":"FAK family"
		},
		{
			"name":"FES family"
		},
		{
			"name":"JAK family [OT]"
		},
		{
			"name":"SRC family"
		},
		{
			"name":"TEC family"
		},
		{
			"name":"SYK family"
		},
		{
			"name":"Other"
		},
		{
			"name":"Bacterial",
			"children":[
			{
				"name":"NCTC1_01021 etk1; cryptic autophosphorylating protein tyrosine kinase Etk,Tyrosine-protein kinase etk,cryptic autophosphorylating protein tyrosine kinase Etk,Capsular polysaccharide biosynthesis protein,exopolysaccharide transport protein family,Chain length determinant protein\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
			},
			{
				"name":"NCTC1_02333 wzc; tyrosine kinase,Tyrosine-protein kinase wzc,tyrosine kinase,Capsular polysaccharide biosynthesis protein,exopolysaccharide transport protein family,Chain length determinant protein\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
			}
			]
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family",
			"children":[
			{
				"name":"NCTC1_00347 phoR; phosphate regulon sensor protein,Phosphate regulon sensor protein phoR,phosphate regulon sensor protein,Predicted periplasmic ligand-binding sensor domain,phosphate regulon sensor kinase PhoR,Domain of unknown function (DUF3329)\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_01206 phoQ; sensor protein PhoQ,Sensor protein PhoQ,sensor protein PhoQ,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,phosphate regulon sensor kinase PhoR,PhoQ Sensor\tK07637 phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_03703 envZ; osmolarity sensor protein,Osmolarity sensor protein EnvZ,osmolarity sensor protein,Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation,heavy metal sensor kinase,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07638 envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_01769 rstB; sensor protein RstB,Sensor protein RstB,sensor protein RstB,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,heavy metal sensor kinase,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07639 rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_04319 cpxA; two-component sensor protein,Sensor protein CpxA,two-component sensor protein,Predicted periplasmic ligand-binding sensor domain,heavy metal sensor kinase,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07640 cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_04812 creC; sensory histidine kinase CreC,Sensor protein CreC,sensory histidine kinase CreC,Uncharacterized protein conserved in bacteria,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07641 creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02359 baeS; signal transduction histidine-protein kinase BaeS,Signal transduction histidine-protein kinase BaeS,signal transduction histidine-protein kinase BaeS,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07642 baeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_00487 cusS; sensor kinase CusS,Sensor kinase CusS,sensor kinase CusS,Predicted periplasmic ligand-binding sensor domain,heavy metal sensor kinase,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07644 cusS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_03323 qseC; putative Sensor protein,Sensor protein qseC,sensor protein QseC,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,heavy metal sensor kinase,His Kinase A (phospho-acceptor) domain\tK07645 qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_00637 kdpD_1; sensor protein KdpD,Sensor protein KdpD,sensor protein KdpD,Osmosensitive K+ channel His kinase sensor domain\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_00638 kdpD_2; sensor protein KdpD,Sensor protein KdpD,sensor protein KdpD,Signal transduction histidine kinase regulating C4-dicarboxylate transport system,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_01031 torS_1; hybrid sensory histidine kinase TorS,Sensor protein torS,hybrid sensory histidine kinase TorS,Uncharacterized domain of BarA-like signal transduction histidine kinases,TMAO reductase sytem sensor TorS,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07647 torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_03527 arcB; aerobic respiration control sensor protein ArcB,Aerobic respiration control sensor protein ArcB,aerobic respiration control sensor protein ArcB,Uncharacterized domain of BarA-like signal transduction histidine kinases,TMAO reductase sytem sensor TorS,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07648 arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02191 yedV; heavy metal sensor histidine kinase,Probable sensor-like histidine kinase YedV,sensor kinase CusS,Predicted periplasmic ligand-binding sensor domain,heavy metal sensor kinase,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NarL family",
			"children":[
			{
				"name":"NCTC1_01293 narX; nitrate\/nitrite sensor protein NarX,Nitrate\/nitrite sensor protein narX,nitrate\/nitrite sensor protein NarX,Signal transduction histidine kinase, nitrate\/nitrite-specific,Histidine kinase\tK07673 narX; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarX [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02761 narQ_2; nitrate\/nitrite sensor protein NarQ,Nitrate\/nitrite sensor protein narX,nitrate\/nitrite sensor protein NarQ,Signal transduction histidine kinase, nitrate\/nitrite-specific,Histidine kinase\tK07674 narQ; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_04095 uhpB; sensory histidine kinase UhpB,Sensor protein degS,sensory histidine kinase UhpB,Signal transduction histidine kinase,MASE1\tK07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02529 yojN_1; phosphotransfer intermediate protein in two-component regulatory system with RcsBC,Sensor-like histidine kinase RcsD,phosphotransfer intermediate protein in two-component regulatory system with RcsBC,Uncharacterized domain of BarA-like signal transduction histidine kinases,TMAO reductase sytem sensor TorS,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07676 rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02532 rcsC; hybrid sensory kinase in two-component regulatory system with RcsB and YojN,Sensor kinase protein RcsC,hybrid sensory kinase in two-component regulatory system with RcsB and YojN,Uncharacterized domain of BarA-like signal transduction histidine kinases,TMAO reductase sytem sensor TorS,RcsC Alpha-Beta-Loop (ABL)\tK07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_03078 barA; hybrid sensory histidine kinase BarA,Signal transduction histidine-protein kinase BarA,hybrid sensory histidine kinase BarA,Uncharacterized domain of BarA-like signal transduction histidine kinases,TMAO reductase sytem sensor TorS,Uncharacterized signal transduction histidine kinase domain (DUF2222)\tK07678 barA; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02673 evgS; hybrid sensory histidine kinase in two-component regulatory system with EvgA,Sensor protein evgS precursor,hybrid sensory histidine kinase in two-component regulatory system with EvgA,Response regulator containing a CheY-like receiver domain and a GGDEF domain,TMAO reductase sytem sensor TorS,Bacterial extracellular solute-binding proteins, family 3\tK07679 evgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Spo family [OT]"
		},
		{
			"name":"CitB family [OT]",
			"children":[
			{
				"name":"NCTC1_04455 yjdH; sensory histidine kinase DcuS,Sensor histidine kinase DcuS,sensory histidine kinase DcuS,Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07701 dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"LytTR family [OT]",
			"children":[
			{
				"name":"NCTC1_02416 yehU; sensor histidine kinase,Probable sensor-like histidine kinase YehU,Predicted signal transduction protein with a C-terminal ATPase domain,5TMR of 5TMR-LYT\tK27882 btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02683 ypdA; YpdA, sensory kinase in two-component system with YpdB,Inner membrane protein ypdA,Predicted signal transduction protein with a C-terminal ATPase domain,phosphate regulon sensor kinase PhoR,Histidine kinase\tK27884 pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NtrC family",
			"children":[
			{
				"name":"NCTC1_04265 glnL; nitrogen regulation protein NR(II),Nitrogen regulation protein NR(II),nitrogen regulation protein NR(II),Signal transduction histidine kinase, nitrogen specific,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_04423 zraS; sensor protein ZraS,Sensor protein ZraS,sensor protein ZraS,Signal transduction histidine kinase, nitrogen specific,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07709 zraS; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]"
			},
			{
				"name":"NCTC1_02862 yfhK; 2-component sensor protein,Sensor histidine kinase QseE,sensory histidine kinase CreC,Predicted periplasmic ligand-binding sensor domain,phosphate regulon sensor kinase PhoR,Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase\tK07711 glrK; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"CheA family [OT]",
			"children":[
			{
				"name":"NCTC1_02104 cheA; chemotaxis protein CheA,Chemotaxis protein CheA,chemotaxis protein CheA,Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation,TMAO reductase sytem sensor TorS,CheW-like domain\tK03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Cell cycle family [OT]"
		},
		{
			"name":"Lux family [OT]"
		},
		{
			"name":"LuxR family [OT]"
		},
		{
			"name":"Other"
		}
		]
	}
	]
}