{
	"name":"sft04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"NCTC1_00432 htpG; heat shock protein 90,High temperature protein G,heat shock protein 90,Molecular chaperone, HSP90 family,Hsp90 protein\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"NCTC1_03073 eno; phosphopyruvate hydratase,Enolase,enolase,L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily,phosphopyruvate hydratase,Enolase, C-terminal TIM barrel domain\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"NCTC1_01553 gapA; gIyceraldehyde-3-phosphate dehydrogenase (phosphorylating),Glyceraldehyde-3-phosphate dehydrogenase A,glyceraldehyde-3-phosphate dehydrogenase A,Transketolase,glyceraldehyde-3-phosphate dehydrogenase, type I,Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"NCTC1_01931 gap; glyceraldehyde-3-phosphate dehydrogenase,Glyceraldehyde-3-phosphate dehydrogenase,glyceraldehyde-3-phosphate dehydrogenase,Transketolase,glyceraldehyde-3-phosphate dehydrogenase, type I,Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"NCTC1_03203 pgk; phosphoglycerate kinase,Phosphoglycerate kinase,phosphoglycerate kinase,3-phosphoglycerate kinase,Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"NCTC1_01850 pykF; Pyruvate kinase I,Pyruvate kinase I,pyruvate kinase,pyruvate kinase,Pyruvate kinase, barrel domain\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"NCTC1_02019 pykA; pyruvate kinase,Pyruvate kinase II,pyruvate kinase,pyruvate kinase,Pyruvate kinase, barrel domain\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"NCTC1_03662 ppiA; peptidyl-prolyl cis-trans isomerase,Peptidyl-prolyl cis-trans isomerase A precursor,peptidyl-prolyl cis-trans isomerase A (rotamase A),Cyclophilin type peptidyl-prolyl cis-trans isomerase\/CLD\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"NCTC1_03346 yqiK; SPFH\/band 7 domain-containing protein,Inner membrane protein yqiK,Uncharacterized protein conserved in bacteria\tK07192 FLOT; flotillin"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"NCTC1_04666 groEL; chaperonin GroEL,hypothetical protein,chaperonin GroEL,chaperonin GroL,TCP-1\/cpn60 chaperonin family\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC1_00014 dnaK_1; molecular chaperone DnaK,Heat shock protein 70,molecular chaperone DnaK,Ethanolamine utilization protein, possible chaperonin,chaperone protein DnaK,Hsp70 protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC1_04546 pgi; glucose-6-phosphate isomerase,Glucose-6-phosphate isomerase,glucose-6-phosphate isomerase,Phosphoglucose isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC1_02809 guaB; Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase,inosine 5'-monophosphate dehydrogenase,L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases,inosine-5'-monophosphate dehydrogenase,IMP dehydrogenase \/ GMP reductase domain\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC1_03637 tuf2_1; elongation factor Tu,Elongation factor Tu 1,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC1_04397 tuf2_2; elongation factor Tu,P-43,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC1_01161 hinT; purine nucleoside phosphoramidase,HIT-like protein hinT,purine nucleoside phosphoramidase,HIT domain\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells",
			"children":[
			{
				"name":"NCTC1_02709 sodium:bile acid symporter family protein\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast milk"
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"NCTC1_04666 groEL; chaperonin GroEL,hypothetical protein,chaperonin GroEL,chaperonin GroL,TCP-1\/cpn60 chaperonin family\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC1_03142 thlA; acetyl-CoA acetyltransferase,Acetyl-CoA acetyltransferase,acetyl-CoA acetyltransferase,Transcription-associated recombination protein,acetyl-CoA C-acetyltransferase,Thiolase, N-terminal domain\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"NCTC1_00433 adk; adenylate kinase,Adenylate kinase,adenylate kinase,adenylate kinase,Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"NCTC1_00428 apt; adenine phosphoribosyltransferase,Adenine phosphoribosyltransferase,adenine phosphoribosyltransferase,GTP cyclohydrolase I,adenine phosphoribosyltransferase,Phosphoribosyl transferase domain\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"NCTC1_04371 argH; argininosuccinate lyase,Argininosuccinate lyase,argininosuccinate lyase,Argininosuccinate lyase,argininosuccinate lyase,Lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"NCTC1_03486 argG; argininosuccinate synthase,Argininosuccinate synthase,argininosuccinate synthase,Argininosuccinate synthase,argininosuccinate synthase,Arginosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"NCTC1_04624 fbp; fructose-1,6-bisphosphatase,Fructose-1,6-bisphosphatase class 1,fructose-1,6-bisphosphatase,Fructose-1-6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
			},
			{
				"name":"NCTC1_00576 galK; galactokinase,Galactokinase,galactokinase, Galactokinase,galactokinase,Galactokinase galactose-binding signature\tK00849 galK; galactokinase [EC:2.7.1.6]"
			},
			{
				"name":"NCTC1_03736 glgB; glycogen branching protein,1,4-alpha-glucan branching enzyme GlgB,glycogen branching enzyme,Maltooligosyl trehalose synthase,1,4-alpha-glucan branching enzyme,Carbohydrate-binding module 48 (Isoamylase N-terminal domain)\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"NCTC1_04334 glpK; glycerol kinase,Glycerol kinase,glycerol kinase,Pentose-5-phosphate-3-epimerase,glycerol kinase,FGGY family of carbohydrate kinases, N-terminal domain\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"NCTC1_04266 glnA; glutamine synthetase,Glutamine synthetase,glutamine synthetase,Predicted metal-dependent hydrolase of the TIM-barrel fold,glutamine synthetase, type I,Glutamine synthetase, catalytic domain\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"NCTC1_04546 pgi; glucose-6-phosphate isomerase,Glucose-6-phosphate isomerase,glucose-6-phosphate isomerase,Phosphoglucose isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC1_00262 hemB; delta-aminolevulinic acid dehydratase,Delta-aminolevulinic acid dehydratase,delta-aminolevulinic acid dehydratase,Delta-aminolevulinic acid dehydratase,Delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"NCTC1_00241 phoA; alkaline phosphatase,Alkaline phosphatase precursor,alkaline phosphatase,Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"NCTC1_03190 serA; D-3-phosphoglycerate dehydrogenase,D-3-phosphoglycerate dehydrogenase,Phosphoserine aminotransferase,phosphoglycerate dehydrogenase,D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"NCTC1_04426 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase,Bifunctional purine biosynthesis protein PurH,bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase,Folate-dependent phosphoribosylglycinamide formyltransferase PurN,phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase,AICARFT\/IMPCHase bienzyme\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"NCTC1_00114 lpd; putative pyruvate\/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component,-like enzyme,Dihydrolipoyl dehydrogenase,dihydrolipoamide dehydrogenase,Uncharacterized conserved protein,dihydrolipoyl dehydrogenase,Pyridine nucleotide-disulphide oxidoreductase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"NCTC1_00039 fixB; electron transfer flavoprotein FixB,Electron transfer flavoprotein large subunit,putative electron transfer flavoprotein FixB,Rubredoxin,Electron transfer flavoprotein FAD-binding domain\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"NCTC1_02016 zwf; glucose-6-phosphate 1-dehydrogenase,Glucose-6-phosphate 1-dehydrogenase,glucose-6-phosphate dehydrogenase,Glucose-6-phosphate dehydrogenase, C-terminal domain\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC1_02809 guaB; Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase,inosine 5'-monophosphate dehydrogenase,L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases,inosine-5'-monophosphate dehydrogenase,IMP dehydrogenase \/ GMP reductase domain\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"NCTC1_00014 dnaK_1; molecular chaperone DnaK,Heat shock protein 70,molecular chaperone DnaK,Ethanolamine utilization protein, possible chaperonin,chaperone protein DnaK,Hsp70 protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC1_04666 groEL; chaperonin GroEL,hypothetical protein,chaperonin GroEL,chaperonin GroL,TCP-1\/cpn60 chaperonin family\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC1_03637 tuf2_1; elongation factor Tu,Elongation factor Tu 1,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC1_04397 tuf2_2; elongation factor Tu,P-43,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"NCTC1_04666 groEL; chaperonin GroEL,hypothetical protein,chaperonin GroEL,chaperonin GroL,TCP-1\/cpn60 chaperonin family\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC1_04546 pgi; glucose-6-phosphate isomerase,Glucose-6-phosphate isomerase,glucose-6-phosphate isomerase,Phosphoglucose isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"NCTC1_02016 zwf; glucose-6-phosphate 1-dehydrogenase,Glucose-6-phosphate 1-dehydrogenase,glucose-6-phosphate dehydrogenase,Glucose-6-phosphate dehydrogenase, C-terminal domain\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC1_00014 dnaK_1; molecular chaperone DnaK,Heat shock protein 70,molecular chaperone DnaK,Ethanolamine utilization protein, possible chaperonin,chaperone protein DnaK,Hsp70 protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"NCTC1_04327 tpiA; triosephosphate isomerase,Triosephosphate isomerase,triosephosphate isomerase,triose-phosphate isomerase,Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"NCTC1_03637 tuf2_1; elongation factor Tu,Elongation factor Tu 1,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"NCTC1_04397 tuf2_2; elongation factor Tu,P-43,elongation factor Tu,GTPases-translation elongation factors,translation elongation factor Tu,Elongation factor Tu GTP binding domain\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"NCTC1_04666 groEL; chaperonin GroEL,hypothetical protein,chaperonin GroEL,chaperonin GroL,TCP-1\/cpn60 chaperonin family\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"NCTC1_02016 zwf; glucose-6-phosphate 1-dehydrogenase,Glucose-6-phosphate 1-dehydrogenase,glucose-6-phosphate dehydrogenase,Glucose-6-phosphate dehydrogenase, C-terminal domain\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"NCTC1_00578 gpmA; phosphoglyceromutase,2, 3-bisphosphoglycerate-dependent phosphoglycerate mutase,phosphoglyceromutase,phosphoglycerate mutase 1 family,Histidine phosphatase superfamily (branch 1)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"NCTC1_04327 tpiA; triosephosphate isomerase,Triosephosphate isomerase,triosephosphate isomerase,triose-phosphate isomerase,Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"NCTC1_00578 gpmA; phosphoglyceromutase,2, 3-bisphosphoglycerate-dependent phosphoglycerate mutase,phosphoglyceromutase,phosphoglycerate mutase 1 family,Histidine phosphatase superfamily (branch 1)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"NCTC1_04327 tpiA; triosephosphate isomerase,Triosephosphate isomerase,triosephosphate isomerase,triose-phosphate isomerase,Triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells",
			"children":[
			{
				"name":"NCTC1_04676 blc; outer membrane lipoprotein Blc,Outer membrane lipoprotein blc precursor,outer membrane lipoprotein Blc,Bacterial lipocalin,Lipocalin-like domain\tK03098 APOD; apolipoprotein D and lipocalin family protein"
			}
			]
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}