{
	"name":"shg00001",
	"children":[
	{
		"name":"09100 Metabolism",
		"children":[
		{
			"name":"09101 Carbohydrate metabolism",
			"children":[
			{
				"name":"00010 Glycolysis \/ Gluconeogenesis [PATH:shg00010]",
				"children":[
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_0676 Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_3994 fructose-bisphosphate aldolase, class II\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Sph21_3045 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Sph21_0067 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3255 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3892 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_5090 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_0066 Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Sph21_2987 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Sph21_1354 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Sph21_1149 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1309 Pyruvate dehydrogenase (acetyl-transferring)\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1150 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_4787 Mannitol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_0595 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1023 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1348 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1982 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_2273 HAD-superfamily hydrolase, subfamily IA, variant 3\tK20866 yihX; glucose-1-phosphatase [EC:3.1.3.10]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_3674 Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))\tK00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]"
				},
				{
					"name":"Sph21_3016 Phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				}
				]
			},
			{
				"name":"00020 Citrate cycle (TCA cycle) [PATH:shg00020]",
				"children":[
				{
					"name":"Sph21_3626 citrate synthase I\tK01647 CS; citrate synthase [EC:2.3.3.1]"
				},
				{
					"name":"Sph21_4145 2-methylcitrate synthase\/citrate synthase II\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"Sph21_0046 aconitate hydratase 1\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_2236 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_0366 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_3146 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_1684 2-oxoglutarate dehydrogenase, E1 subunit\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]"
				},
				{
					"name":"Sph21_1685 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_2539 Dihydrolipoyllysine-residue acetyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2418 succinyl-CoA synthetase, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_3338 Succinyl-CoA ligase (ADP-forming) subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_1710 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"Sph21_1404 succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1403 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1405 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_4874 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_1523 Fumarate hydratase class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_2252 malate:quinone oxidoreductase\tK00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]"
				},
				{
					"name":"Sph21_3016 Phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"Sph21_1149 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1309 Pyruvate dehydrogenase (acetyl-transferring)\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1150 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				}
				]
			},
			{
				"name":"00030 Pentose phosphate pathway [PATH:shg00030]",
				"children":[
				{
					"name":"Sph21_0676 Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Sph21_4277 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
				},
				{
					"name":"Sph21_4278 6-phosphogluconolactonase\tK01057 PGLS; 6-phosphogluconolactonase [EC:3.1.1.31]"
				},
				{
					"name":"Sph21_1612 6-phosphogluconolactonase\tK07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31]"
				},
				{
					"name":"Sph21_4276 6-phosphogluconate dehydrogenase, decarboxylating\tK00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]"
				},
				{
					"name":"Sph21_3089 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Sph21_2191 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2617 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2618 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3915 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3916 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2192 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"Sph21_3182 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"Sph21_0015 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Sph21_4275 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_5156 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"Sph21_0579 KDPG and KHG aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"Sph21_4580 2-dehydro-3-deoxyphosphogluconate aldolase\/4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"Sph21_3674 Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))\tK00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]"
				},
				{
					"name":"Sph21_3176 3-oxoacyl-(acyl-carrier-protein) reductase\tK00034 gdh; glucose 1-dehydrogenase [EC:1.1.1.47]"
				},
				{
					"name":"Sph21_2765 Quinoprotein glucose dehydrogenase\tK00117 gcd; quinoprotein glucose dehydrogenase [EC:1.1.5.2]"
				},
				{
					"name":"Sph21_1253 Gluconolactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_4037 SMP-30\/Gluconolaconase\/LRE-like region-containing protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_4554 Gluconokinase\tK25031 gntK; gluconokinase [EC:2.7.1.12]"
				},
				{
					"name":"Sph21_0578 PfkB domain protein\tK00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]"
				},
				{
					"name":"Sph21_3994 fructose-bisphosphate aldolase, class II\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				}
				]
			},
			{
				"name":"00040 Pentose and glucuronate interconversions [PATH:shg00040]",
				"children":[
				{
					"name":"Sph21_2881 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				},
				{
					"name":"Sph21_2885 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				},
				{
					"name":"Sph21_0475 hypothetical protein\tK01730 ogl; oligogalacturonide lyase [EC:4.2.2.6]"
				},
				{
					"name":"Sph21_2820 Cupin 2 conserved barrel domain protein\tK26933 kdgF; unsaturated pyranuronate lyase [EC:4.2.99.25]"
				},
				{
					"name":"Sph21_0728 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase\tK01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17]"
				},
				{
					"name":"Sph21_0726 2-deoxy-D-gluconate 3-dehydrogenase\tK00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127]"
				},
				{
					"name":"Sph21_0575 Uronate isomerase\tK01812 uxaC; glucuronate isomerase [EC:5.3.1.12]"
				},
				{
					"name":"Sph21_2894 Uronate isomerase\tK01812 uxaC; glucuronate isomerase [EC:5.3.1.12]"
				},
				{
					"name":"Sph21_2892 Tagaturonate reductase\tK00041 uxaB; tagaturonate reductase [EC:1.1.1.58]"
				},
				{
					"name":"Sph21_0622 Altronate dehydratase\tK01685 uxaA; altronate hydrolase [EC:4.2.1.7]"
				},
				{
					"name":"Sph21_2893 Altronate dehydratase\tK01685 uxaA; altronate hydrolase [EC:4.2.1.7]"
				},
				{
					"name":"Sph21_0576 mannonate dehydratase\tK01686 uxuA; mannonate dehydratase [EC:4.2.1.8]"
				},
				{
					"name":"Sph21_1960 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_2004 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_1030 L-ribulose-5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				},
				{
					"name":"Sph21_3089 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Sph21_1031 L-arabinose isomerase\tK01804 araA; L-arabinose isomerase [EC:5.3.1.4]"
				},
				{
					"name":"Sph21_0610 L-ribulokinase\tK00853 araB; L-ribulokinase [EC:2.7.1.16]"
				},
				{
					"name":"Sph21_1029 Ribulokinase\tK00853 araB; L-ribulokinase [EC:2.7.1.16]"
				},
				{
					"name":"Sph21_3964 Xylulokinase\tK00854 xylB; xylulokinase [EC:2.7.1.17]"
				},
				{
					"name":"Sph21_3963 Xylose isomerase\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Sph21_0515 Xylose isomerase domain-containing protein TIM barrel\tK01820 rhaA; L-rhamnose isomerase \/ sugar isomerase [EC:5.3.1.14 5.3.1.-]"
				},
				{
					"name":"Sph21_0982 Dihydrodipicolinate synthase\tK22397 yjhH; 2-dehydro-3-deoxy-D-pentonate aldolase [EC:4.1.2.28]"
				},
				{
					"name":"Sph21_2642 fumarylacetoacetate (FAA) hydrolase\tK14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]"
				},
				{
					"name":"Sph21_0989 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				},
				{
					"name":"Sph21_2641 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				},
				{
					"name":"Sph21_0436 Xylulokinase\tK22935 XK1; D-ribulokinase [EC:2.7.1.47]"
				},
				{
					"name":"Sph21_0612 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				}
				]
			},
			{
				"name":"00051 Fructose and mannose metabolism [PATH:shg00051]",
				"children":[
				{
					"name":"Sph21_0933 Endoglucanase H\/Glycosyl hydrolase family 26\tK01218 gmuG; mannan endo-1,4-beta-mannosidase [EC:3.2.1.78]"
				},
				{
					"name":"Sph21_4785 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"Sph21_3998 Phosphoglucosamine mutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"Sph21_2002 Mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"Sph21_1755 GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"Sph21_1941 GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"Sph21_2012 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]"
				},
				{
					"name":"Sph21_0612 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				},
				{
					"name":"Sph21_2776 NADP-dependent oxidoreductase domain\tK00064 E1.1.1.122; D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]"
				},
				{
					"name":"Sph21_4773 Pyridoxal 4-dehydrogenase\tK00064 E1.1.1.122; D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]"
				},
				{
					"name":"Sph21_0623 protein of unknown function DUF718\tK29028 E5.1.3.29; L-fucose mutarotase [EC:5.1.3.29]"
				},
				{
					"name":"Sph21_0618 3-oxoacyl-(acyl-carrier-protein) reductase\tK18333 E1.1.1.435; L-fucose dehydrogenase [EC:1.1.1.435]"
				},
				{
					"name":"Sph21_0619 amidohydrolase 2\tK07046 E3.1.1.120; L-fucono-1,5-lactonase [EC:3.1.1.120]"
				},
				{
					"name":"Sph21_0515 Xylose isomerase domain-containing protein TIM barrel\tK01820 rhaA; L-rhamnose isomerase \/ sugar isomerase [EC:5.3.1.14 5.3.1.-]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_3963 Xylose isomerase\tK01805 xylA; xylose isomerase [EC:5.3.1.5]"
				},
				{
					"name":"Sph21_3994 fructose-bisphosphate aldolase, class II\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Sph21_3045 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Sph21_4784 Fructan beta-fructosidase\tK03332 fruA; fructan beta-fructosidase [EC:3.2.1.80]"
				},
				{
					"name":"Sph21_0015 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Sph21_4275 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				}
				]
			},
			{
				"name":"00052 Galactose metabolism [PATH:shg00052]",
				"children":[
				{
					"name":"Sph21_0595 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1023 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1348 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1982 Aldose 1-epimerase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"Sph21_1349 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Sph21_1050 UDP-glucose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1756 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_1975 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2304 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2327 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2338 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2864 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_4567 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2646 Beta-galactosidase\tK12308 bgaB; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2648 Beta-galactosidase\tK12308 bgaB; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_4066 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Sph21_4263 carbohydrate binding family 6\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Sph21_1031 L-arabinose isomerase\tK01804 araA; L-arabinose isomerase [EC:5.3.1.4]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_2640 Galactonate dehydratase\tK01684 dgoD; galactonate dehydratase [EC:4.2.1.6]"
				},
				{
					"name":"Sph21_4581 Galactonate dehydratase\tK01684 dgoD; galactonate dehydratase [EC:4.2.1.6]"
				},
				{
					"name":"Sph21_4583 2-keto-3-deoxy-galactonokinase\tK00883 dgoK; 2-dehydro-3-deoxygalactonokinase [EC:2.7.1.58]"
				},
				{
					"name":"Sph21_3807 alpha amylase catalytic region\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"Sph21_5140 glycoside hydrolase family 31\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				}
				]
			},
			{
				"name":"00053 Ascorbate and aldarate metabolism [PATH:shg00053]",
				"children":[
				{
					"name":"Sph21_1960 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_2004 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_0198 Inositol oxygenase\tK00469 MIOX; inositol oxygenase [EC:1.13.99.1]"
				},
				{
					"name":"Sph21_1253 Gluconolactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_4037 SMP-30\/Gluconolaconase\/LRE-like region-containing protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_2776 NADP-dependent oxidoreductase domain\tK00064 E1.1.1.122; D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]"
				},
				{
					"name":"Sph21_4773 Pyridoxal 4-dehydrogenase\tK00064 E1.1.1.122; D-threo-aldose 1-dehydrogenase [EC:1.1.1.122]"
				},
				{
					"name":"Sph21_1030 L-ribulose-5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				},
				{
					"name":"Sph21_2642 fumarylacetoacetate (FAA) hydrolase\tK14259 kdaD; 2-dehydro-3-deoxy-D-arabinonate dehydratase [EC:4.2.1.141]"
				},
				{
					"name":"Sph21_0989 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				},
				{
					"name":"Sph21_2641 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				}
				]
			},
			{
				"name":"00500 Starch and sucrose metabolism [PATH:shg00500]",
				"children":[
				{
					"name":"Sph21_3807 alpha amylase catalytic region\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"Sph21_5140 glycoside hydrolase family 31\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"Sph21_1423 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3133 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3949 beta-galactosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_4498 glycoside hydrolase family 5\tK01179 E3.2.1.4; endoglucanase [EC:3.2.1.4]"
				},
				{
					"name":"Sph21_5137 Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				},
				{
					"name":"Sph21_1635 Starch synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Sph21_5138 Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Sph21_2180 1,4-alpha-glucan-branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"Sph21_5139 1,4-alpha-glucan-branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"Sph21_2181 trehalose synthase\tK05343 treS; maltose alpha-D-glucosyltransferase \/ alpha-amylase [EC:5.4.99.16 3.2.1.1]"
				},
				{
					"name":"Sph21_3806 Maltose alpha-D-glucosyltransferase\tK05343 treS; maltose alpha-D-glucosyltransferase \/ alpha-amylase [EC:5.4.99.16 3.2.1.1]"
				},
				{
					"name":"Sph21_2182 alpha amylase catalytic region\tK16147 glgE; starch synthase (maltosyl-transferring) [EC:2.4.99.16]"
				},
				{
					"name":"Sph21_0315 glycogen debranching enzyme GlgX\tK01214 ISA; isoamylase [EC:3.2.1.68]"
				},
				{
					"name":"Sph21_0314 malto-oligosyltrehalose trehalohydrolase\tK01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]"
				},
				{
					"name":"Sph21_3794 malto-oligosyltrehalose trehalohydrolase\tK01236 treZ; maltooligosyltrehalose trehalohydrolase [EC:3.2.1.141]"
				},
				{
					"name":"Sph21_1323 trehalose-phosphatase\tK16055 TPS; trehalose 6-phosphate synthase\/phosphatase [EC:2.4.1.15 3.1.3.12]"
				},
				{
					"name":"Sph21_1252 Alpha,alpha-trehalase\tK01194 TREH; alpha,alpha-trehalase [EC:3.2.1.28]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_0676 Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Sph21_4785 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				}
				]
			},
			{
				"name":"00620 Pyruvate metabolism [PATH:shg00620]",
				"children":[
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_1149 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1309 Pyruvate dehydrogenase (acetyl-transferring)\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1150 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_4787 Mannitol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"Sph21_1354 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Sph21_2237 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_0012 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Sph21_0013 acetyl-CoA carboxylase, biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Sph21_3995 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_1140 Acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"Sph21_1710 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"Sph21_2205 Pyruvate dehydrogenase (cytochrome)\tK00156 poxB; pyruvate dehydrogenase (quinone) [EC:1.2.5.1]"
				},
				{
					"name":"Sph21_2899 D-lactate dehydrogenase\tK03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28]"
				},
				{
					"name":"Sph21_4107 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]"
				},
				{
					"name":"Sph21_4356 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]"
				},
				{
					"name":"Sph21_1341 beta-lactamase domain protein\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]"
				},
				{
					"name":"Sph21_2086 malic protein NAD-binding protein\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_2252 malate:quinone oxidoreductase\tK00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]"
				},
				{
					"name":"Sph21_1523 Fumarate hydratase class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"Sph21_3165 Phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"Sph21_3016 Phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_2283 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:shg00630]",
				"children":[
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_3626 citrate synthase I\tK01647 CS; citrate synthase [EC:2.3.3.1]"
				},
				{
					"name":"Sph21_4145 2-methylcitrate synthase\/citrate synthase II\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"Sph21_0046 aconitate hydratase 1\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_2236 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_1533 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_4886 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_5077 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_3869 Glyoxylate reductase\tK00015 gyaR; glyoxylate reductase [EC:1.1.1.26]"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Sph21_2084 Glycine dehydrogenase (decarboxylating)\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"Sph21_1168 Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2197 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"Sph21_3452 Xylose isomerase domain-containing protein TIM barrel\tK01816 hyi; hydroxypyruvate isomerase [EC:5.3.1.22]"
				},
				{
					"name":"Sph21_4632 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Sph21_0579 KDPG and KHG aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"Sph21_4580 2-dehydro-3-deoxyphosphogluconate aldolase\/4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"Sph21_1646 formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]"
				}
				]
			},
			{
				"name":"00640 Propanoate metabolism [PATH:shg00640]",
				"children":[
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2237 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_0012 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Sph21_0013 acetyl-CoA carboxylase, biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Sph21_3995 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_3338 Succinyl-CoA ligase (ADP-forming) subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_2418 succinyl-CoA synthetase, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_4145 2-methylcitrate synthase\/citrate synthase II\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"Sph21_4146 2-methylcitrate dehydratase\tK01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]"
				},
				{
					"name":"Sph21_0046 aconitate hydratase 1\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_2236 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_4144 methylisocitrate lyase\tK03417 prpB; methylisocitrate lyase [EC:4.1.3.30]"
				}
				]
			},
			{
				"name":"00650 Butanoate metabolism [PATH:shg00650]",
				"children":[
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_3111 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]"
				},
				{
					"name":"Sph21_0021 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"Sph21_0758 Enoyl-CoA hydratase\tK01715 crt; short-chain-enoyl-CoA hydratase [EC:4.2.1.150]"
				},
				{
					"name":"Sph21_1404 succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1403 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1405 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_4874 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_5246 succinic semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"Sph21_1710 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"Sph21_2967 Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"Sph21_4669 3-oxoacid CoA-transferase, A subunit\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]"
				},
				{
					"name":"Sph21_4666 3-oxoacid CoA-transferase, B subunit\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]"
				},
				{
					"name":"Sph21_2289 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2287 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				}
				]
			},
			{
				"name":"00660 C5-Branched dibasic acid metabolism [PATH:shg00660]",
				"children":[
				{
					"name":"Sph21_2289 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2287 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_3338 Succinyl-CoA ligase (ADP-forming) subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_2418 succinyl-CoA synthetase, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_2280 (R)-citramalate synthase\tK09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]"
				},
				{
					"name":"Sph21_2282 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Sph21_2281 3-isopropylmalate dehydratase, small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Sph21_2279 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				}
				]
			},
			{
				"name":"00562 Inositol phosphate metabolism [PATH:shg00562]",
				"children":[
				{
					"name":"Sph21_3623 Inositol-phosphate phosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]"
				},
				{
					"name":"Sph21_4643 phytase\tK01083 E3.1.3.8; 3-phytase [EC:3.1.3.8]"
				},
				{
					"name":"Sph21_5106 Myo-inositol-1-phosphate synthase\tK01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]"
				},
				{
					"name":"Sph21_0662 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_1769 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_0198 Inositol oxygenase\tK00469 MIOX; inositol oxygenase [EC:1.13.99.1]"
				},
				{
					"name":"Sph21_3045 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				}
				]
			},
			{
				"name":"00566 Sulfoquinovose metabolism",
				"children":[
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				}
				]
			}
			]
		},
		{
			"name":"09102 Energy metabolism",
			"children":[
			{
				"name":"00190 Oxidative phosphorylation [PATH:shg00190]",
				"children":[
				{
					"name":"Sph21_1587 NAD(P)H-quinone oxidoreductase subunit 3\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_3180 NAD(P)H-quinone oxidoreductase subunit 3\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1588 NAD(P)H-quinone oxidoreductase subunit K\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_3179 NAD(P)H-quinone oxidoreductase subunit K\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1589 NAD(P)H-quinone oxidoreductase subunit J\tK00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_3341 NAD(P)H-quinone oxidoreductase subunit J\tK00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1590 NAD(P)H-quinone oxidoreductase subunit H\tK00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_3340 NAD(P)H-quinone oxidoreductase subunit H\tK00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1591 NADH-quinone oxidoreductase, E subunit\tK00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1592 NADH-quinone oxidoreductase, F subunit\tK00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1593 NADH dehydrogenase\tK00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1594 NADH dehydrogenase (quinone)\tK00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2206 NADH dehydrogenase (quinone)\tK00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1595 NAD(P)H-quinone oxidoreductase subunit I\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2207 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1596 NADH-ubiquinone\/plastoquinone oxidoreductase chain 6\tK00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1597 NAD(P)H-quinone oxidoreductase subunit 4L\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2209 NAD(P)H-quinone oxidoreductase subunit 4L\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1598 proton-translocating NADH-quinone oxidoreductase, chain L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2210 proton-translocating NADH-quinone oxidoreductase, chain L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1599 proton-translocating NADH-quinone oxidoreductase, chain M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2211 proton-translocating NADH-quinone oxidoreductase, chain M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1600 NAD(P)H-quinone oxidoreductase subunit 2\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2212 NAD(P)H-quinone oxidoreductase subunit 2\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_2208 NADH-ubiquinone\/plastoquinone oxidoreductase chain 6\tK05578 ndhG; NAD(P)H-quinone oxidoreductase subunit 6 [EC:7.1.1.2]"
				},
				{
					"name":"Sph21_1704 NADH dehydrogenase (ubiquinone)\tK03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]"
				},
				{
					"name":"Sph21_4547 NADH dehydrogenase (ubiquinone)\tK03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]"
				},
				{
					"name":"Sph21_4903 NADH dehydrogenase (ubiquinone)\tK03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]"
				},
				{
					"name":"Sph21_1404 succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1403 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1405 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_4874 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_1557 Protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"Sph21_1560 hypothetical protein\tK02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1558 cytochrome c oxidase, subunit III\tK02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1559 cytochrome c oxidase subunit III\tK02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1555 cytochrome c oxidase subunit I\tK02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1913 cytochrome c oxidase subunit I\tK02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1554 cytochrome c oxidase subunit II\tK02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_1556 cytochrome oxidase assembly\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"Sph21_3527 cytochrome c oxidase, cbb3-type, subunit I\tK15862 ccoNO; cytochrome c oxidase cbb3-type subunit I\/II [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_3529 cytochrome c class I\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III"
				},
				{
					"name":"Sph21_1182 cytochrome bd ubiquinol oxidase subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]"
				},
				{
					"name":"Sph21_1183 cytochrome bd ubiquinol oxidase subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]"
				},
				{
					"name":"Sph21_5232 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"Sph21_2292 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"Sph21_5231 ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"Sph21_5233 ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"Sph21_2291 ATPase, F1 complex, delta\/epsilon subunit\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"Sph21_5236 ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"Sph21_5234 ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"Sph21_5235 ATP synthase subunit c\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"Sph21_1602 Inorganic pyrophosphatase\tK01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]"
				},
				{
					"name":"Sph21_0532 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_3169 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_2713 polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]"
				}
				]
			},
			{
				"name":"00195 Photosynthesis"
			},
			{
				"name":"00196 Photosynthesis - antenna proteins"
			},
			{
				"name":"00710 Carbon fixation by Calvin cycle [PATH:shg00710]",
				"children":[
				{
					"name":"Sph21_0066 Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Sph21_0067 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3255 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3892 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_5090 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3994 fructose-bisphosphate aldolase, class II\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_2191 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2617 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2618 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3915 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3916 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_0015 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Sph21_4275 sugar-phosphate isomerase, RpiB\/LacA\/LacB family\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"Sph21_3045 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"Sph21_3089 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"Sph21_2192 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"Sph21_3182 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"Sph21_3165 Phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"Sph21_3016 Phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"Sph21_2086 malic protein NAD-binding protein\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				}
				]
			},
			{
				"name":"00720 Other carbon fixation pathways [PATH:shg00720]",
				"children":[
				{
					"name":"Sph21_3165 Phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_1523 Fumarate hydratase class II\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"Sph21_1404 succinate dehydrogenase or fumarate reductase, flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1403 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"Sph21_1405 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_4874 succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"Sph21_2418 succinyl-CoA synthetase, alpha subunit\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_3338 Succinyl-CoA ligase (ADP-forming) subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_0366 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_3146 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_0046 aconitate hydratase 1\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_2236 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"Sph21_2237 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_0012 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Sph21_0013 acetyl-CoA carboxylase, biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Sph21_3995 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_3450 Bifunctional protein folD\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"Sph21_0381 Methylenetetrahydrofolate reductase (NAD(P)H)\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				}
				]
			},
			{
				"name":"00680 Methane metabolism [PATH:shg00680]",
				"children":[
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Sph21_3165 Phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_3994 fructose-bisphosphate aldolase, class II\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_2987 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"Sph21_0005 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0434 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0741 amino acid-binding ACT domain protein\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3091 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3090 Phosphoserine aminotransferase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Sph21_1338 Phosphosulfolactate synthase\tK08097 comA; phosphosulfolactate synthase [EC:4.4.1.19]"
				},
				{
					"name":"Sph21_1169 2-phosphosulfolactate phosphatase\tK05979 comB; 2-phosphosulfolactate phosphatase [EC:3.1.3.71]"
				}
				]
			},
			{
				"name":"00910 Nitrogen metabolism [PATH:shg00910]",
				"children":[
				{
					"name":"Sph21_3753 major facilitator superfamily MFS_1\tK02575 NRT2; MFS transporter, NNP family, nitrate\/nitrite transporter"
				},
				{
					"name":"Sph21_3754 Nitrite reductase (NAD(P)H)\tK00367 narB; ferredoxin-nitrate reductase [EC:1.7.7.2]"
				},
				{
					"name":"Sph21_2694 Nitrate reductase\tK00372 nasC; assimilatory nitrate reductase catalytic subunit [EC:1.7.99.-]"
				},
				{
					"name":"Sph21_3748 nitrite reductase (NAD(P)H), large subunit\tK00362 nirB; nitrite reductase (NADH) large subunit [EC:1.7.1.15]"
				},
				{
					"name":"Sph21_3747 nitrite reductase (NAD(P)H), small subunit\tK00363 nirD; nitrite reductase (NADH) small subunit [EC:1.7.1.15]"
				},
				{
					"name":"Sph21_0947 2-nitropropane dioxygenase\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]"
				},
				{
					"name":"Sph21_4164 2-nitropropane dioxygenase\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]"
				},
				{
					"name":"Sph21_2983 Glutamate dehydrogenase (NAD(P)(+))\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"Sph21_3428 Glutamate dehydrogenase (NADP(+))\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3183 Glutamate synthase (ferredoxin)\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Sph21_3184 glutamate synthase, NADH\/NADPH, small subunit\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Sph21_2129 carbonic anhydrase\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]"
				},
				{
					"name":"Sph21_3973 Carbonate dehydratase\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]"
				}
				]
			},
			{
				"name":"00920 Sulfur metabolism [PATH:shg00920]",
				"children":[
				{
					"name":"Sph21_3195 sulfate adenylyltransferase, large subunit\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_3194 sulfate adenylyltransferase, small subunit\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_1242 phosphoesterase RecJ domain protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				},
				{
					"name":"Sph21_3193 Phosphoadenylyl-sulfate reductase (thioredoxin)\tK00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]"
				},
				{
					"name":"Sph21_4717 Nitrate reductase (NADPH)\tK17225 soxC; sulfane dehydrogenase subunit SoxC"
				},
				{
					"name":"Sph21_4718 cytochrome c class I\tK22622 soxD; S-disulfanyl-L-cysteine oxidoreductase SoxD [EC:1.8.2.6]"
				},
				{
					"name":"Sph21_3190 Ferredoxin--nitrite reductase\tK00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]"
				},
				{
					"name":"Sph21_2152 cytochrome c class I\tK19713 tsdA; thiosulfate dehydrogenase [EC:1.8.2.2]"
				},
				{
					"name":"Sph21_3588 Rhodanese-like protein\tK03972 pspE; thiosulfate sulfurtransferase [EC:2.8.1.1]"
				},
				{
					"name":"Sph21_2030 transferase hexapeptide repeat containing protein\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_4128 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_4638 Cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"Sph21_3382 homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]"
				},
				{
					"name":"Sph21_0555 Cystathionine gamma-lyase\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"09103 Lipid metabolism",
			"children":[
			{
				"name":"00061 Fatty acid biosynthesis [PATH:shg00061]",
				"children":[
				{
					"name":"Sph21_2237 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_0012 acetyl-CoA carboxylase, biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"Sph21_0013 acetyl-CoA carboxylase, biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"Sph21_3995 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"Sph21_1356 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Sph21_3686 hypothetical protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Sph21_1317 malonyl CoA-acyl carrier protein transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Sph21_0011 3-oxoacyl-(acyl-carrier-protein) synthase 3\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_2077 Beta-ketoacyl-acyl-carrier-protein synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_2124 Beta-ketoacyl-acyl-carrier-protein synthase I\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_1357 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_4075 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_0337 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2365 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2703 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_4360 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_1541 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"Sph21_0398 Enoyl-(acyl-carrier-protein) reductase (NADH)\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]"
				},
				{
					"name":"Sph21_4113 Acyl-(acyl-carrier-protein) desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				},
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				}
				]
			},
			{
				"name":"00062 Fatty acid elongation"
			},
			{
				"name":"00071 Fatty acid degradation [PATH:shg00071]",
				"children":[
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"Sph21_0021 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"Sph21_2999 Glutaryl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_1500 Enoyl-CoA hydratase\/isomerase\tK13238 ECI1; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]"
				}
				]
			},
			{
				"name":"00073 Cutin, suberine and wax biosynthesis"
			},
			{
				"name":"00074 Mycolic acid biosynthesis [PATH:shg00074]",
				"children":[
				{
					"name":"Sph21_1356 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Sph21_3686 hypothetical protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Sph21_1317 malonyl CoA-acyl carrier protein transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Sph21_4113 Acyl-(acyl-carrier-protein) desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				}
				]
			},
			{
				"name":"00100 Steroid biosynthesis"
			},
			{
				"name":"00120 Primary bile acid biosynthesis"
			},
			{
				"name":"00121 Secondary bile acid biosynthesis"
			},
			{
				"name":"00140 Steroid hormone biosynthesis"
			},
			{
				"name":"00561 Glycerolipid metabolism [PATH:shg00561]",
				"children":[
				{
					"name":"Sph21_4632 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Sph21_4787 Mannitol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"Sph21_4544 Glycerone kinase\tK28825 dhaK; glycerone kinase [EC:2.7.1.29]"
				},
				{
					"name":"Sph21_2623 Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Sph21_2908 Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Sph21_0010 Phosphate acyltransferase\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"Sph21_2990 Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"Sph21_1576 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Sph21_4066 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Sph21_4263 carbohydrate binding family 6\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				}
				]
			},
			{
				"name":"00564 Glycerophospholipid metabolism [PATH:shg00564]",
				"children":[
				{
					"name":"Sph21_2602 Glycerol-3-phosphate dehydrogenase (NAD(P)(+))\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]"
				},
				{
					"name":"Sph21_3880 Glycerol-3-phosphate dehydrogenase (NAD(P)+)\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]"
				},
				{
					"name":"Sph21_2909 Glycerol-3-phosphate dehydrogenase\tK00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]"
				},
				{
					"name":"Sph21_2990 Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"Sph21_1576 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"Sph21_0662 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_1769 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_4465 phospholipase A1\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]"
				},
				{
					"name":"Sph21_0438 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"Sph21_1706 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"Sph21_2903 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"Sph21_1305 phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]"
				},
				{
					"name":"Sph21_4020 CDP-alcohol phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]"
				},
				{
					"name":"Sph21_1368 Phosphatidylserine decarboxylase proenzyme\tK01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]"
				},
				{
					"name":"Sph21_4029 phospholipase D\/Transphosphatidylase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]"
				},
				{
					"name":"Sph21_2155 CDP-alcohol phosphatidyltransferase\tK08744 CRLS; cardiolipin synthase (CMP-forming) [EC:2.7.8.41]"
				}
				]
			},
			{
				"name":"00565 Ether lipid metabolism [PATH:shg00565]",
				"children":[
				{
					"name":"Sph21_4465 phospholipase A1\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]"
				},
				{
					"name":"Sph21_0662 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_1769 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				}
				]
			},
			{
				"name":"00600 Sphingolipid metabolism [PATH:shg00600]",
				"children":[
				{
					"name":"Sph21_3026 Glycine C-acetyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"Sph21_3689 fatty acid desaturase\tK04712 DEGS; sphingolipid 4-desaturase\/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]"
				},
				{
					"name":"Sph21_3027 hypothetical protein\tK28560 bcerS; bacterial ceramide synthase [EC:2.3.1.-]"
				},
				{
					"name":"Sph21_2358 Glucan endo-1,6-beta-glucosidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"Sph21_1756 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_1975 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2304 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2327 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2338 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2864 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_4567 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_4587 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_4589 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_5174 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_4066 Alpha-galactosidase\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Sph21_4263 carbohydrate binding family 6\tK07407 E3.2.1.22B; alpha-galactosidase [EC:3.2.1.22]"
				},
				{
					"name":"Sph21_0646 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0655 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0656 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1083 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_3771 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				}
				]
			},
			{
				"name":"00590 Arachidonic acid metabolism",
				"children":[
				{
					"name":"Sph21_4465 phospholipase A1\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]"
				}
				]
			},
			{
				"name":"00591 Linoleic acid metabolism",
				"children":[
				{
					"name":"Sph21_4465 phospholipase A1\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]"
				}
				]
			},
			{
				"name":"00592 alpha-Linolenic acid metabolism [PATH:shg00592]",
				"children":[
				{
					"name":"Sph21_4465 phospholipase A1\tK01058 pldA; phospholipase A1\/A2 [EC:3.1.1.32 3.1.1.4]"
				},
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"01040 Biosynthesis of unsaturated fatty acids [PATH:shg01040]",
				"children":[
				{
					"name":"Sph21_4485 fatty acid desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]"
				},
				{
					"name":"Sph21_4113 Acyl-(acyl-carrier-protein) desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				}
				]
			}
			]
		},
		{
			"name":"09104 Nucleotide metabolism",
			"children":[
			{
				"name":"00230 Purine metabolism [PATH:shg00230]",
				"children":[
				{
					"name":"Sph21_4472 NUDIX hydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_5156 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"Sph21_2214 Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"Sph21_1499 Phosphoribosylamine--glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]"
				},
				{
					"name":"Sph21_2384 phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"Sph21_3859 Phosphoribosylformylglycinamidine synthase\tK01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]"
				},
				{
					"name":"Sph21_3984 Phosphoribosylformylglycinamidine cyclo-ligase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]"
				},
				{
					"name":"Sph21_3178 phosphoribosylaminoimidazole carboxylase, ATPase subunit\tK01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]"
				},
				{
					"name":"Sph21_3177 phosphoribosylaminoimidazole carboxylase, catalytic subunit\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]"
				},
				{
					"name":"Sph21_2531 Phosphoribosylaminoimidazole-succinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]"
				},
				{
					"name":"Sph21_3621 adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"Sph21_2382 phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Sph21_2249 Adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"Sph21_3410 5 nucleotidase deoxy cytosolic type C\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Sph21_3321 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_5177 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_0349 purine nucleoside phosphorylase I, inosine and guanosine-specific\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Sph21_1367 hypoxanthine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]"
				},
				{
					"name":"Sph21_3644 inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"Sph21_1241 Nucleoside diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"Sph21_1466 Nucleoside-triphosphatase rdgB\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]"
				},
				{
					"name":"Sph21_2239 GMP synthase (glutamine-hydrolyzing)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"Sph21_3237 Guanine deaminase\tK01487 guaD; guanine deaminase [EC:3.5.4.3]"
				},
				{
					"name":"Sph21_1513 Guanylate kinase\tK00942 gmk; guanylate kinase [EC:2.7.4.8]"
				},
				{
					"name":"Sph21_0339 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2913 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_0340 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2914 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_1251 deoxyguanosinetriphosphate triphosphohydrolase\tK01129 dgt; dGTPase [EC:3.1.5.1]"
				},
				{
					"name":"Sph21_3499 hypothetical protein\tK06952 yfdR; 5'-nucleotidase [EC:3.1.3.89]"
				},
				{
					"name":"Sph21_2995 (p)ppGpp synthetase I, SpoT\/RelA\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"Sph21_3170 Ppx\/GppA phosphatase\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]"
				},
				{
					"name":"Sph21_2259 adenylate\/guanylate cyclase\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]"
				},
				{
					"name":"Sph21_4271 putative adenylate\/guanylate cyclase\tK01768 E4.6.1.1; adenylate cyclase [EC:4.6.1.1]"
				},
				{
					"name":"Sph21_2993 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Sph21_4725 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Sph21_3513 Deoxyadenosine kinase\tK15519 dck; deoxyadenosine\/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]"
				},
				{
					"name":"Sph21_2927 AMP nucleosidase\tK01241 amn; AMP nucleosidase [EC:3.2.2.4]"
				},
				{
					"name":"Sph21_0074 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"Sph21_2556 metallophosphoesterase\tK03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]"
				},
				{
					"name":"Sph21_4731 metallophosphoesterase\tK03651 cpdA; 3',5'-cyclic-AMP phosphodiesterase [EC:3.1.4.53]"
				},
				{
					"name":"Sph21_3195 sulfate adenylyltransferase, large subunit\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_3194 sulfate adenylyltransferase, small subunit\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				}
				]
			},
			{
				"name":"00240 Pyrimidine metabolism [PATH:shg00240]",
				"children":[
				{
					"name":"Sph21_1122 carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_0334 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_2230 Aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"Sph21_2958 amidohydrolase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"Sph21_3886 Allantoinase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"Sph21_5136 dihydroorotase, multifunctional complex type\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"Sph21_3536 Dihydroorotate dehydrogenase\tK00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]"
				},
				{
					"name":"Sph21_3151 orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]"
				},
				{
					"name":"Sph21_4018 Orotidine 5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]"
				},
				{
					"name":"Sph21_1043 uridylate kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]"
				},
				{
					"name":"Sph21_1241 Nucleoside diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"Sph21_3141 Septum formation protein Maf\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]"
				},
				{
					"name":"Sph21_3519 CTP synthase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]"
				},
				{
					"name":"Sph21_3135 Cytidylate kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]"
				},
				{
					"name":"Sph21_4665 Uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]"
				},
				{
					"name":"Sph21_3410 5 nucleotidase deoxy cytosolic type C\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Sph21_3321 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_5177 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_3393 purine or other phosphorylase family 1\tK00757 udp; uridine phosphorylase [EC:2.4.2.3]"
				},
				{
					"name":"Sph21_0722 phosphoribosyltransferase\tK00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Sph21_1147 phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Sph21_2231 Uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Sph21_0679 deoxycytidine triphosphate deaminase\tK01494 dcd; dCTP deaminase [EC:3.5.4.13]"
				},
				{
					"name":"Sph21_0339 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2913 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_0340 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2914 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_3499 hypothetical protein\tK06952 yfdR; 5'-nucleotidase [EC:3.1.3.89]"
				},
				{
					"name":"Sph21_3513 Deoxyadenosine kinase\tK15519 dck; deoxyadenosine\/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]"
				},
				{
					"name":"Sph21_2216 CMP\/dCMP deaminase zinc-binding protein\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"Sph21_2373 Thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]"
				},
				{
					"name":"Sph21_2973 Thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"Sph21_5208 Serine 3-dehydrogenase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"09105 Amino acid metabolism",
			"children":[
			{
				"name":"00250 Alanine, aspartate and glutamate metabolism [PATH:shg00250]",
				"children":[
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_1297 L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]"
				},
				{
					"name":"Sph21_1245 L-asparaginase, type I\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"Sph21_0527 Beta-aspartyl-peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"Sph21_3307 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"Sph21_3276 Nitrilase\/cyanide hydratase and apolipoprotein N-acyltransferase\tK13566 NIT2; omega-amidase [EC:3.5.1.3]"
				},
				{
					"name":"Sph21_1536 Alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]"
				},
				{
					"name":"Sph21_1034 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Sph21_1042 Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Sph21_2993 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Sph21_4725 Adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"Sph21_3621 adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"Sph21_2230 Aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"Sph21_5246 succinic semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"Sph21_3183 Glutamate synthase (ferredoxin)\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Sph21_3184 glutamate synthase, NADH\/NADPH, small subunit\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"Sph21_2983 Glutamate dehydrogenase (NAD(P)(+))\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"Sph21_3428 Glutamate dehydrogenase (NADP(+))\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Sph21_0351 delta-1-pyrroline-5-carboxylate dehydrogenase\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_1122 carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_0334 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_2063 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"Sph21_2214 Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				}
				]
			},
			{
				"name":"00260 Glycine, serine and threonine metabolism [PATH:shg00260]",
				"children":[
				{
					"name":"Sph21_3171 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_4675 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_1430 aspartate kinase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Sph21_1075 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Sph21_3383 Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"Sph21_1429 Homoserine kinase\tK00872 thrB; homoserine kinase [EC:2.7.1.39]"
				},
				{
					"name":"Sph21_1428 threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				},
				{
					"name":"Sph21_1477 Threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]"
				},
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Sph21_4632 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"Sph21_2987 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"Sph21_0005 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0434 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0741 amino acid-binding ACT domain protein\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3091 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3090 Phosphoserine aminotransferase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Sph21_5208 Serine 3-dehydrogenase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				},
				{
					"name":"Sph21_0050 Glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Sph21_1459 2-amino-3-ketobutyrate coenzyme A ligase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Sph21_2084 Glycine dehydrogenase (decarboxylating)\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"Sph21_1168 Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2197 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"Sph21_4020 CDP-alcohol phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]"
				},
				{
					"name":"Sph21_2928 Cysteine synthase\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"Sph21_4650 Cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"Sph21_0704 L-serine dehydratase 1\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"Sph21_2278 threonine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"Sph21_3103 Tryptophan synthase alpha chain\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]"
				},
				{
					"name":"Sph21_3102 Tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				}
				]
			},
			{
				"name":"00270 Cysteine and methionine metabolism [PATH:shg00270]",
				"children":[
				{
					"name":"Sph21_2030 transferase hexapeptide repeat containing protein\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_4128 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_4638 Cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"Sph21_4650 Cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"Sph21_1916 Cys\/Met metabolism pyridoxal-phosphate-dependent protein\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"Sph21_2928 Cysteine synthase\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"Sph21_0379 methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]"
				},
				{
					"name":"Sph21_5265 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"Sph21_1577 S-adenosylmethionine synthase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Sph21_0870 purine or other phosphorylase family 1\tK01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]"
				},
				{
					"name":"Sph21_3037 GAF domain-containing protein\tK08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]"
				},
				{
					"name":"Sph21_0901 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_3497 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_1238 Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"Sph21_3171 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_4675 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_1430 aspartate kinase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Sph21_1075 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Sph21_3383 Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"Sph21_1429 Homoserine kinase\tK00872 thrB; homoserine kinase [EC:2.7.1.39]"
				},
				{
					"name":"Sph21_3382 homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]"
				},
				{
					"name":"Sph21_3381 O-acetylhomoserine\/O-acetylserine sulfhydrylase\tK01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]"
				},
				{
					"name":"Sph21_0555 Cystathionine gamma-lyase\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]"
				},
				{
					"name":"Sph21_0743 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3549 Aminodeoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3933 Malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"Sph21_0704 L-serine dehydratase 1\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"Sph21_4127 cysteine synthase B\tK12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144]"
				},
				{
					"name":"Sph21_0005 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0434 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0741 amino acid-binding ACT domain protein\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3091 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3090 Phosphoserine aminotransferase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00280 Valine, leucine and isoleucine degradation [PATH:shg00280]",
				"children":[
				{
					"name":"Sph21_0743 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3549 Aminodeoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_4008 Leucine dehydrogenase\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"Sph21_1191 3-hydroxyisobutyrate dehydrogenase\tK00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]"
				},
				{
					"name":"Sph21_3285 Methylcrotonoyl-CoA carboxylase\tK01969 MCCC2; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]"
				},
				{
					"name":"Sph21_2967 Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"Sph21_4669 3-oxoacid CoA-transferase, A subunit\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]"
				},
				{
					"name":"Sph21_4666 3-oxoacid CoA-transferase, B subunit\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:shg00290]",
				"children":[
				{
					"name":"Sph21_2278 threonine dehydratase\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"Sph21_2280 (R)-citramalate synthase\tK09011 cimA; (R)-citramalate synthase [EC:2.3.3.21]"
				},
				{
					"name":"Sph21_2282 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Sph21_2281 3-isopropylmalate dehydratase, small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"Sph21_2279 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				},
				{
					"name":"Sph21_2289 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2287 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2285 Ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"Sph21_2290 Dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"Sph21_0743 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3549 Aminodeoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_4008 Leucine dehydrogenase\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]"
				},
				{
					"name":"Sph21_2283 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00300 Lysine biosynthesis [PATH:shg00300]",
				"children":[
				{
					"name":"Sph21_3383 Homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"Sph21_3171 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_4675 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_1430 aspartate kinase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Sph21_1075 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Sph21_0049 Dihydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_2300 dihydrodipicolinate synthetase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_4588 dihydrodipicolinate synthetase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_0425 Dihydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				},
				{
					"name":"Sph21_2428 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase\tK00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]"
				},
				{
					"name":"Sph21_1037 Acetylornithine transaminase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"Sph21_1106 Diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]"
				},
				{
					"name":"Sph21_1606 LL-diaminopimelate aminotransferase\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"Sph21_3172 diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				},
				{
					"name":"Sph21_0060 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Sph21_1352 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"Sph21_4678 Alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				}
				]
			},
			{
				"name":"00310 Lysine degradation [PATH:shg00310]",
				"children":[
				{
					"name":"Sph21_1336 L-aminoadipate-semialdehyde dehydrogenase\tK26061 amaB; L-aminoadipate-semialdehyde dehydrogenase"
				},
				{
					"name":"Sph21_1685 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_2539 Dihydrolipoyllysine-residue acetyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2999 Glutaryl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_5246 succinic semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00220 Arginine biosynthesis [PATH:shg00220]",
				"children":[
				{
					"name":"Sph21_1034 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Sph21_1042 Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Sph21_2761 Arginase\/agmatinase\/formiminoglutamase\tK01476 rocF; arginase [EC:3.5.3.1]"
				},
				{
					"name":"Sph21_3006 Arginine deiminase\tK01478 arcA; arginine deiminase [EC:3.5.3.6]"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_1122 carbamoyl-phosphate synthase, large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_0334 carbamoyl-phosphate synthase, small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"Sph21_2983 Glutamate dehydrogenase (NAD(P)(+))\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"Sph21_3428 Glutamate dehydrogenase (NADP(+))\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_1039 acetylglutamate kinase\tK00930 argB; acetylglutamate kinase [EC:2.7.2.8]"
				},
				{
					"name":"Sph21_1035 N-acetyl-gamma-glutamyl-phosphate reductase\tK00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]"
				},
				{
					"name":"Sph21_1037 Acetylornithine transaminase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"Sph21_1041 peptidase M20\tK01438 argE; acetylornithine deacetylase [EC:3.5.1.16]"
				}
				]
			},
			{
				"name":"00330 Arginine and proline metabolism [PATH:shg00330]",
				"children":[
				{
					"name":"Sph21_3004 Orn\/DAP\/Arg decarboxylase 2, C-terminal protein\tK01585 speA; arginine decarboxylase [EC:4.1.1.19]"
				},
				{
					"name":"Sph21_0332 Agmatine deiminase\tK10536 aguA; agmatine deiminase [EC:3.5.3.12]"
				},
				{
					"name":"Sph21_0331 N-carbamoylputrescine amidase\tK12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]"
				},
				{
					"name":"Sph21_2761 Arginase\/agmatinase\/formiminoglutamase\tK01476 rocF; arginase [EC:3.5.3.1]"
				},
				{
					"name":"Sph21_1040 pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]"
				},
				{
					"name":"Sph21_2274 Proline dehydrogenase\tK00318 PRODH; proline dehydrogenase [EC:1.5.5.2]"
				},
				{
					"name":"Sph21_0351 delta-1-pyrroline-5-carboxylate dehydrogenase\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]"
				},
				{
					"name":"Sph21_3653 Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"Sph21_3652 Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				},
				{
					"name":"Sph21_4185 alpha\/beta hydrolase fold protein\tK01259 pip; proline iminopeptidase [EC:3.4.11.5]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				}
				]
			},
			{
				"name":"00340 Histidine metabolism [PATH:shg00340]",
				"children":[
				{
					"name":"Sph21_5142 ATP phosphoribosyltransferase\tK00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]"
				},
				{
					"name":"Sph21_5149 Phosphoribosyl-ATP pyrophosphatase\tK11755 hisIE; phosphoribosyl-AMP cyclohydrolase \/ phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]"
				},
				{
					"name":"Sph21_5147 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase\tK01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]"
				},
				{
					"name":"Sph21_5146 Imidazole glycerol phosphate synthase subunit hisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]"
				},
				{
					"name":"Sph21_5148 Imidazole glycerol phosphate synthase subunit hisF\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]"
				},
				{
					"name":"Sph21_5145 Imidazoleglycerol-phosphate dehydratase\tK01089 hisB; imidazoleglycerol-phosphate dehydratase \/ histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Sph21_5143 Histidinol dehydrogenase\tK00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]"
				},
				{
					"name":"Sph21_3303 histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				},
				{
					"name":"Sph21_3302 urocanate hydratase\tK01712 hutU; urocanate hydratase [EC:4.2.1.49]"
				},
				{
					"name":"Sph21_3301 imidazolonepropionase\tK01468 hutI; imidazolonepropionase [EC:3.5.2.7]"
				},
				{
					"name":"Sph21_0739 Arginase\/agmatinase\/formiminoglutamase\tK01479 hutG; formiminoglutamase [EC:3.5.3.8]"
				},
				{
					"name":"Sph21_3300 Formimidoylglutamase\tK01479 hutG; formiminoglutamase [EC:3.5.3.8]"
				},
				{
					"name":"Sph21_0649 Histidine decarboxylase\tK01590 hdc; histidine decarboxylase [EC:4.1.1.22]"
				},
				{
					"name":"Sph21_2565 Protein of unknown function DUF2260\tK18911 egtD; L-histidine Nalpha-methyltransferase [EC:2.1.1.44]"
				}
				]
			},
			{
				"name":"00350 Tyrosine metabolism [PATH:shg00350]",
				"children":[
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Sph21_5246 succinic semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00360 Phenylalanine metabolism [PATH:shg00360]",
				"children":[
				{
					"name":"Sph21_4119 Oxidoreductase FAD-binding domain protein\tK02613 paaE; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE"
				},
				{
					"name":"Sph21_3111 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Sph21_0987 D-amino-acid dehydrogenase\tK00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]"
				},
				{
					"name":"Sph21_2594 Catalase-peroxidase\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]"
				}
				]
			},
			{
				"name":"00380 Tryptophan metabolism [PATH:shg00380]",
				"children":[
				{
					"name":"Sph21_1685 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_2539 Dihydrolipoyllysine-residue acetyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2999 Glutaryl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_1533 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_4886 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_5077 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_2594 Catalase-peroxidase\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]"
				}
				]
			},
			{
				"name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:shg00400]",
				"children":[
				{
					"name":"Sph21_0448 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]"
				},
				{
					"name":"Sph21_2276 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]"
				},
				{
					"name":"Sph21_3159 3-dehydroquinate dehydratase, type II\tK03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]"
				},
				{
					"name":"Sph21_5255 Shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]"
				},
				{
					"name":"Sph21_3220 3-phosphoshikimate 1-carboxyvinyltransferase\tK00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]"
				},
				{
					"name":"Sph21_3219 chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]"
				},
				{
					"name":"Sph21_1506 Anthranilate synthase\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"Sph21_1507 glutamine amidotransferase of anthranilate synthase\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"Sph21_3100 Anthranilate phosphoribosyltransferase\tK00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]"
				},
				{
					"name":"Sph21_3101 Phosphoribosylanthranilate isomerase\tK01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]"
				},
				{
					"name":"Sph21_1508 Indole-3-glycerol-phosphate synthase\tK01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]"
				},
				{
					"name":"Sph21_3103 Tryptophan synthase alpha chain\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]"
				},
				{
					"name":"Sph21_3102 Tryptophan synthase beta chain\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				},
				{
					"name":"Sph21_3221 3-deoxy-7-phosphoheptulonate synthase\tK04516 AROA1; chorismate mutase [EC:5.4.99.5]"
				},
				{
					"name":"Sph21_1605 Prephenate dehydrogenase\tK04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]"
				},
				{
					"name":"Sph21_3222 Prephenate dehydratase\tK04518 pheA2; prephenate dehydratase [EC:4.2.1.51]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			}
			]
		},
		{
			"name":"09106 Metabolism of other amino acids",
			"children":[
			{
				"name":"00410 beta-Alanine metabolism [PATH:shg00410]",
				"children":[
				{
					"name":"Sph21_1637 Aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				},
				{
					"name":"Sph21_1636 Pantothenate synthetase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]"
				}
				]
			},
			{
				"name":"00430 Taurine and hypotaurine metabolism [PATH:shg00430]",
				"children":[
				{
					"name":"Sph21_3879 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_5118 Gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_1536 Alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]"
				}
				]
			},
			{
				"name":"00440 Phosphonate and phosphinate metabolism",
				"children":[
				{
					"name":"Sph21_3873 beta-lactamase domain protein\tK06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]"
				}
				]
			},
			{
				"name":"00450 Selenocompound metabolism [PATH:shg00450]",
				"children":[
				{
					"name":"Sph21_1916 Cys\/Met metabolism pyridoxal-phosphate-dependent protein\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"Sph21_0379 methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]"
				},
				{
					"name":"Sph21_5265 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"Sph21_4650 Cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"Sph21_4014 cysteine desulfurase, SufS subfamily\tK11717 sufS; cysteine desulfurase \/ selenocysteine lyase [EC:2.8.1.7 4.4.1.16]"
				},
				{
					"name":"Sph21_2969 Ferredoxin--NADP reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"Sph21_3286 thioredoxin reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"Sph21_3195 sulfate adenylyltransferase, large subunit\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_3194 sulfate adenylyltransferase, small subunit\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_2962 L-seryl-tRNA(ser) selenium transferase protein\tK01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]"
				},
				{
					"name":"Sph21_1427 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				}
				]
			},
			{
				"name":"00460 Cyanoamino acid metabolism [PATH:shg00460]",
				"children":[
				{
					"name":"Sph21_1423 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3133 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3949 beta-galactosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3879 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_5118 Gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_1245 L-asparaginase, type I\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"Sph21_0527 Beta-aspartyl-peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				}
				]
			},
			{
				"name":"00470 D-Amino acid metabolism [PATH:shg00470]",
				"children":[
				{
					"name":"Sph21_4678 Alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"Sph21_3074 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Sph21_3157 Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"Sph21_0058 UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Sph21_3252 Mandelate racemase\/muconate lactonizing protein\tK19802 ycjG; L-Ala-D\/L-Glu epimerase \/ N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]"
				},
				{
					"name":"Sph21_3543 Muconate cycloisomerase\tK19802 ycjG; L-Ala-D\/L-Glu epimerase \/ N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]"
				},
				{
					"name":"Sph21_1106 Diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]"
				},
				{
					"name":"Sph21_3172 diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				},
				{
					"name":"Sph21_0988 4-hydroxyproline epimerase\tK12658 lhpA; 4-hydroxyproline epimerase [EC:5.1.1.8]"
				},
				{
					"name":"Sph21_0990 Dihydrodipicolinate synthase\tK21062 lhpC; 1-pyrroline-4-hydroxy-2-carboxylate deaminase [EC:3.5.4.22]"
				},
				{
					"name":"Sph21_0989 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				},
				{
					"name":"Sph21_2641 Aldehyde dehydrogenase (NADP(+))\tK13877 aldH; 2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]"
				},
				{
					"name":"Sph21_0987 D-amino-acid dehydrogenase\tK00285 dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]"
				}
				]
			},
			{
				"name":"00480 Glutathione metabolism [PATH:shg00480]",
				"children":[
				{
					"name":"Sph21_3879 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_5118 Gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_2710 UPF0271 protein ybgL\tK07160 pxpA; 5-oxoprolinase (ATP-hydrolysing) subunit A [EC:3.5.2.9]"
				},
				{
					"name":"Sph21_4118 Glutathione synthase\tK01920 gshB; glutathione synthase [EC:6.3.2.3]"
				},
				{
					"name":"Sph21_1641 Membrane alanyl aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]"
				},
				{
					"name":"Sph21_0366 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_3146 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_4276 6-phosphogluconate dehydrogenase, decarboxylating\tK00033 PGD; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]"
				},
				{
					"name":"Sph21_4277 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
				},
				{
					"name":"Sph21_0032 Peroxiredoxin\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]"
				},
				{
					"name":"Sph21_2997 glutathione peroxidase\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]"
				}
				]
			}
			]
		},
		{
			"name":"09107 Glycan biosynthesis and metabolism",
			"children":[
			{
				"name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:shg00520]",
				"children":[
				{
					"name":"Sph21_3769 Anhydro-N-acetylmuramic acid kinase\tK09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]"
				},
				{
					"name":"Sph21_3259 N-acetylmuramic acid 6-phosphate etherase\tK07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126]"
				},
				{
					"name":"Sph21_0108 N-acylglucosamine 2-epimerase\tK01787 RENBP; N-acylglucosamine 2-epimerase [EC:5.1.3.8]"
				},
				{
					"name":"Sph21_1828 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]"
				},
				{
					"name":"Sph21_2929 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Sph21_1700 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Sph21_2699 Chitinase\tK01183 E3.2.1.14; chitinase [EC:3.2.1.14]"
				},
				{
					"name":"Sph21_0789 Beta-N-acetylhexosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0790 Beta-N-acetylhexosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0646 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0655 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0656 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1083 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_3771 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1908 Mannosylglycoprotein endo-beta-mannosidase\tK15855 csxA; exo-1,4-beta-D-glucosaminidase [EC:3.2.1.165]"
				},
				{
					"name":"Sph21_2846 N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"Sph21_4115 N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"Sph21_0371 Glucosamine-6-phosphate deaminase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"Sph21_1509 glucosamine-6-phosphate isomerase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"Sph21_2063 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"Sph21_4785 Fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"Sph21_0676 Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Sph21_1025 alpha-L-arabinofuranosidase domain protein\tK01209 abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55]"
				},
				{
					"name":"Sph21_1026 alpha-L-arabinofuranosidase domain protein\tK01209 abfA; alpha-L-arabinofuranosidase [EC:3.2.1.55]"
				},
				{
					"name":"Sph21_4162 glycoside hydrolase family 43\tK15921 xynD; arabinoxylan arabinofuranohydrolase [EC:3.2.1.55]"
				},
				{
					"name":"Sph21_2647 Xylan 1,4-beta-xylosidase\tK01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37]"
				},
				{
					"name":"Sph21_2653 Xylan 1,4-beta-xylosidase\tK01198 xynB; xylan 1,4-beta-xylosidase [EC:3.2.1.37]"
				},
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_1960 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_2004 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_1349 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Sph21_1050 UDP-glucose 4-epimerase\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"Sph21_3998 Phosphoglucosamine mutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"Sph21_2002 Mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"Sph21_5137 Glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				},
				{
					"name":"Sph21_1754 glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				}
				]
			},
			{
				"name":"00541 Biosynthesis of various nucleotide sugars [PATH:shg00541]",
				"children":[
				{
					"name":"Sph21_1811 nucleotide sugar dehydrogenase\tK02474 wbpO; UDP-N-acetyl-D-glucosamine\/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]"
				},
				{
					"name":"Sph21_1815 N-acetylneuraminate synthase\tK18430 legI; N,N'-diacetyllegionaminate synthase [EC:2.5.1.101]"
				},
				{
					"name":"Sph21_3363 KpsF\/GutQ family protein\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]"
				},
				{
					"name":"Sph21_3365 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]"
				},
				{
					"name":"Sph21_3140 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]"
				},
				{
					"name":"Sph21_3514 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]"
				},
				{
					"name":"Sph21_4586 N-acetylneuraminate lyase\tK01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]"
				},
				{
					"name":"Sph21_1828 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]"
				},
				{
					"name":"Sph21_3830 hydrolase, HAD-superfamily, subfamily IIIA\tK03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]"
				},
				{
					"name":"Sph21_3829 cytidyltransferase-related domain protein\tK03272 gmhC; D-beta-D-heptose 7-phosphate kinase \/ D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]"
				},
				{
					"name":"Sph21_1960 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_2004 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"Sph21_1754 glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"Sph21_1049 UDP-glucuronate decarboxylase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1051 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1566 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"Sph21_2081 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"Sph21_2294 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"Sph21_2002 Mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"Sph21_1755 GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"Sph21_1941 GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"Sph21_2012 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]"
				}
				]
			},
			{
				"name":"00510 N-Glycan biosynthesis"
			},
			{
				"name":"00513 Various types of N-glycan biosynthesis"
			},
			{
				"name":"00512 Mucin type O-glycan biosynthesis"
			},
			{
				"name":"00515 Mannose type O-glycan biosynthesis"
			},
			{
				"name":"00514 Other types of O-glycan biosynthesis"
			},
			{
				"name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate"
			},
			{
				"name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin"
			},
			{
				"name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate"
			},
			{
				"name":"00531 Glycosaminoglycan degradation"
			},
			{
				"name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
			},
			{
				"name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series"
			},
			{
				"name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series"
			},
			{
				"name":"00604 Glycosphingolipid biosynthesis - ganglio series"
			},
			{
				"name":"00511 Other glycan degradation [PATH:shg00511]",
				"children":[
				{
					"name":"Sph21_4587 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_4589 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_5174 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_1756 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_1975 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2304 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2327 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2338 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_2864 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_4567 Beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"Sph21_0646 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0655 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0656 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1083 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_3771 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_4307 glycosyl hydrolase 38 domain protein\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"Sph21_0603 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0657 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0729 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_1768 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2056 coagulation factor 5\/8 type domain protein\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2166 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2860 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2863 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2868 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3373 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3374 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4700 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4801 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0636 Alpha-L-fucosidase\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2303 Alpha-L-fucosidase\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2865 Alpha-L-fucosidase\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2882 Alpha-L-fucosidase\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4157 Alpha-L-fucosidase\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3890 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase\tK01444 AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]"
				},
				{
					"name":"Sph21_2358 Glucan endo-1,6-beta-glucosidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				}
				]
			},
			{
				"name":"00540 Lipopolysaccharide biosynthesis [PATH:shg00540]",
				"children":[
				{
					"name":"Sph21_1542 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"Sph21_1541 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"Sph21_1540 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]"
				},
				{
					"name":"Sph21_1451 metallophosphoesterase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]"
				},
				{
					"name":"Sph21_5175 lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]"
				},
				{
					"name":"Sph21_0350 Tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]"
				},
				{
					"name":"Sph21_1048 Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]"
				},
				{
					"name":"Sph21_1257 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_3162 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_4379 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_4142 Protein of unknown function DUF2219\tK09953 lpxR; lipid A 3-O-deacylase [EC:3.1.1.-]"
				}
				]
			},
			{
				"name":"00542 O-Antigen repeat unit biosynthesis [PATH:shg00542]",
				"children":[
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00550 Peptidoglycan biosynthesis [PATH:shg00550]",
				"children":[
				{
					"name":"Sph21_2929 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Sph21_1700 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Sph21_0055 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"Sph21_0058 UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Sph21_0060 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Sph21_3074 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Sph21_1352 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"Sph21_4678 Alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"Sph21_0039 diacylglycerol kinase\tK00887 dgkA; undecaprenol kinase [EC:2.7.1.66]"
				},
				{
					"name":"Sph21_5202 Undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"Sph21_0549 Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_2431 phosphoesterase PA-phosphatase related protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_0059 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Sph21_0056 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"Sph21_2295 Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_3115 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_5240 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_4124 penicillin-binding protein 1C\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_0057 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_2375 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_2376 penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_0061 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_1073 D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				}
				]
			},
			{
				"name":"00552 Teichoic acid biosynthesis [PATH:shg00552]",
				"children":[
				{
					"name":"Sph21_0549 Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_2431 phosphoesterase PA-phosphatase related protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00571 Lipoarabinomannan (LAM) biosynthesis"
			},
			{
				"name":"00572 Arabinogalactan biosynthesis - Mycobacterium",
				"children":[
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00543 Exopolysaccharide biosynthesis [PATH:shg00543]",
				"children":[
				{
					"name":"Sph21_1956 glycosyl transferase group 1\tK03208 wcaI; putative colanic acid biosynthesis glycosyltransferase WcaI"
				},
				{
					"name":"Sph21_1954 transferase hexapeptide repeat containing protein\tK03818 wcaF; putative colanic acid biosynthesis acetyltransferase WcaF [EC:2.3.1.-]"
				},
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1942 membrane bound O-acyl transferase MBOAT family protein\tK19294 algI; alginate O-acetyltransferase complex protein AlgI"
				},
				{
					"name":"Sph21_3331 membrane bound O-acyl transferase MBOAT family protein\tK19294 algI; alginate O-acetyltransferase complex protein AlgI"
				},
				{
					"name":"Sph21_2030 transferase hexapeptide repeat containing protein\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_4128 Serine O-acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"Sph21_1799 glycosyl transferase group 1\tK13658 gumI; beta-1,4-mannosyltransferase [EC:2.4.1.251]"
				},
				{
					"name":"Sph21_2071 glycosyl transferase group 1\tK13658 gumI; beta-1,4-mannosyltransferase [EC:2.4.1.251]"
				},
				{
					"name":"Sph21_1949 exopolysaccharide biosynthesis pyruvyltransferase ExoV\tK13665 gumL; pyruvyltransferase"
				}
				]
			}
			]
		},
		{
			"name":"09108 Metabolism of cofactors and vitamins",
			"children":[
			{
				"name":"00730 Thiamine metabolism [PATH:shg00730]",
				"children":[
				{
					"name":"Sph21_1387 Phosphomethylpyrimidine synthase\tK03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]"
				},
				{
					"name":"Sph21_4500 phosphomethylpyrimidine kinase\tK00941 thiD; hydroxymethylpyrimidine\/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]"
				},
				{
					"name":"Sph21_3019 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3741 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3997 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_1383 thiazole biosynthesis protein ThiH\tK03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]"
				},
				{
					"name":"Sph21_1133 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]"
				},
				{
					"name":"Sph21_1384 Thiazole synthase\tK03149 thiG; thiazole synthase [EC:2.8.1.10]"
				},
				{
					"name":"Sph21_1385 Thiamine-phosphate pyrophosphorylase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]"
				},
				{
					"name":"Sph21_1386 thiamine monophosphate synthase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]"
				},
				{
					"name":"Sph21_1295 thiamine-monophosphate kinase\tK00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]"
				},
				{
					"name":"Sph21_1435 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Sph21_3205 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_0074 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				}
				]
			},
			{
				"name":"00740 Riboflavin metabolism [PATH:shg00740]",
				"children":[
				{
					"name":"Sph21_0565 3,4-dihydroxy-2-butanone 4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]"
				},
				{
					"name":"Sph21_3390 riboflavin biosynthesis protein RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]"
				},
				{
					"name":"Sph21_2691 HAD-superfamily hydrolase, subfamily IA, variant 1\tK20862 yigB; FMN hydrolase \/ 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.102 3.1.3.104]"
				},
				{
					"name":"Sph21_5259 6,7-dimethyl-8-ribityllumazine synthase\tK00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]"
				},
				{
					"name":"Sph21_3897 riboflavin synthase, alpha subunit\tK00793 ribE; riboflavin synthase [EC:2.5.1.9]"
				},
				{
					"name":"Sph21_0551 riboflavin biosynthesis protein RibF\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]"
				},
				{
					"name":"Sph21_4472 NUDIX hydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				},
				{
					"name":"Sph21_5119 3-octaprenyl-4-hydroxybenzoate carboxy-lyase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				}
				]
			},
			{
				"name":"00750 Vitamin B6 metabolism [PATH:shg00750]",
				"children":[
				{
					"name":"Sph21_3342 Pyridoxine\/pyridoxamine 5'-phosphate oxidase\tK00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]"
				},
				{
					"name":"Sph21_3090 Phosphoserine aminotransferase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"Sph21_1240 Pyridoxine 5'-phosphate synthase\tK03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]"
				},
				{
					"name":"Sph21_1428 threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				}
				]
			},
			{
				"name":"00760 Nicotinate and nicotinamide metabolism [PATH:shg00760]",
				"children":[
				{
					"name":"Sph21_1297 L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]"
				},
				{
					"name":"Sph21_1296 Quinolinate synthase A\tK03517 nadA; quinolinate synthase [EC:2.5.1.72]"
				},
				{
					"name":"Sph21_2989 nicotinate-nucleotide pyrophosphorylase\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]"
				},
				{
					"name":"Sph21_3065 nicotinate phosphoribosyltransferase\tK00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]"
				},
				{
					"name":"Sph21_0349 purine nucleoside phosphorylase I, inosine and guanosine-specific\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"Sph21_3410 5 nucleotidase deoxy cytosolic type C\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"Sph21_3321 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_5177 Multifunctional protein surE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"Sph21_1512 nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]"
				},
				{
					"name":"Sph21_5225 NAD+ synthetase\tK01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]"
				},
				{
					"name":"Sph21_3731 CinA domain protein\tK03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]"
				},
				{
					"name":"Sph21_2153 Nicotinamidase\tK08281 pncA; nicotinamidase\/pyrazinamidase [EC:3.5.1.19 3.5.1.-]"
				},
				{
					"name":"Sph21_5204 inorganic polyphosphate\/ATP-NAD kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]"
				},
				{
					"name":"Sph21_1188 (2Fe-2S)-binding domain-containing protein\tK18029 nicA; nicotinate dehydrogenase subunit A [EC:1.17.2.1]"
				},
				{
					"name":"Sph21_1189 Isoquinoline 1-oxidoreductase\tK18030 nicB; nicotinate dehydrogenase subunit B [EC:1.17.2.1]"
				},
				{
					"name":"Sph21_5246 succinic semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00770 Pantothenate and CoA biosynthesis [PATH:shg00770]",
				"children":[
				{
					"name":"Sph21_2289 acetolactate synthase, large subunit, biosynthetic type\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2287 acetolactate synthase, small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"Sph21_2285 Ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"Sph21_2290 Dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"Sph21_0317 3-methyl-2-oxobutanoate hydroxymethyltransferase\tK00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]"
				},
				{
					"name":"Sph21_4591 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]"
				},
				{
					"name":"Sph21_1636 Pantothenate synthetase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]"
				},
				{
					"name":"Sph21_3443 Pantothenate kinase\tK00867 coaA; type I pantothenate kinase [EC:2.7.1.33]"
				},
				{
					"name":"Sph21_1762 phosphopantothenoylcysteine decarboxylase\/phosphopantothenate\/cysteine ligase\tK13038 coaBC; phosphopantothenoylcysteine decarboxylase \/ phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]"
				},
				{
					"name":"Sph21_3153 Phosphopantetheine adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]"
				},
				{
					"name":"Sph21_4003 Dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]"
				},
				{
					"name":"Sph21_0680 4'-phosphopantetheinyl transferase\tK06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]"
				},
				{
					"name":"Sph21_1260 hypothetical protein\tK06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]"
				},
				{
					"name":"Sph21_0743 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3549 Aminodeoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_1637 Aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				}
				]
			},
			{
				"name":"00780 Biotin metabolism [PATH:shg00780]",
				"children":[
				{
					"name":"Sph21_1357 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_4075 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_0337 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2365 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2703 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_4360 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_0398 Enoyl-(acyl-carrier-protein) reductase (NADH)\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]"
				},
				{
					"name":"Sph21_3313 8-amino-7-oxononanoate synthase\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"Sph21_3316 adenosylmethionine-8-amino-7-oxononanoate aminotransferase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]"
				},
				{
					"name":"Sph21_3314 Dethiobiotin synthetase\tK01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]"
				},
				{
					"name":"Sph21_3315 biotin synthase\tK01012 bioB; biotin synthase [EC:2.8.1.6]"
				},
				{
					"name":"Sph21_1059 biotin\/acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Sph21_3026 Glycine C-acetyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				}
				]
			},
			{
				"name":"00785 Lipoic acid metabolism [PATH:shg00785]",
				"children":[
				{
					"name":"Sph21_0702 Octanoyltransferase\tK03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]"
				},
				{
					"name":"Sph21_5263 Lipoyl synthase\tK03644 lipA; lipoyl synthase [EC:2.8.1.8]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_1149 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1309 Pyruvate dehydrogenase (acetyl-transferring)\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"Sph21_1150 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"Sph21_1684 2-oxoglutarate dehydrogenase, E1 subunit\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]"
				},
				{
					"name":"Sph21_1685 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_2539 Dihydrolipoyllysine-residue acetyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"Sph21_2084 Glycine dehydrogenase (decarboxylating)\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"Sph21_1168 Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Sph21_2197 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				}
				]
			},
			{
				"name":"00790 Folate biosynthesis [PATH:shg00790]",
				"children":[
				{
					"name":"Sph21_1318 GTP cyclohydrolase 1\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]"
				},
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_1748 dihydroneopterin aldolase\tK01633 folB; 7,8-dihydroneopterin aldolase\/epimerase\/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]"
				},
				{
					"name":"Sph21_4021 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]"
				},
				{
					"name":"Sph21_5252 dihydropteroate synthase\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]"
				},
				{
					"name":"Sph21_2972 dihydrofolate reductase region\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"Sph21_2223 FolC bifunctional protein\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]"
				},
				{
					"name":"Sph21_0565 3,4-dihydroxy-2-butanone 4-phosphate synthase\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]"
				},
				{
					"name":"Sph21_2992 Aminodeoxychorismate synthase\tK01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]"
				},
				{
					"name":"Sph21_1319 6-pyruvoyl tetrahydropterin synthase and hypothetical protein\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"Sph21_2825 transcriptional coactivator\/pterin dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
				},
				{
					"name":"Sph21_3290 Radical SAM domain protein\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"Sph21_3738 molybdenum cofactor biosynthesis protein A\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				},
				{
					"name":"Sph21_0143 molybdopterin biosynthesis MoaE protein\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]"
				},
				{
					"name":"Sph21_5098 molybdopterin biosynthesis MoaE protein\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]"
				},
				{
					"name":"Sph21_3737 molybdenum cofactor synthesis domain protein\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]"
				},
				{
					"name":"Sph21_3752 molybdenum cofactor synthesis domain protein\tK03750 moeA; molybdopterin molybdotransferase [EC:2.10.1.1]"
				},
				{
					"name":"Sph21_3739 4-diphosphocytidyl-2C-methyl-D-erythritol synthase\tK07141 mocA; molybdenum cofactor cytidylyltransferase [EC:2.7.7.76]"
				},
				{
					"name":"Sph21_2686 Molybdopterin-guanine dinucleotide biosynthesis protein A\tK03752 mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]"
				}
				]
			},
			{
				"name":"00670 One carbon pool by folate [PATH:shg00670]",
				"children":[
				{
					"name":"Sph21_2972 dihydrofolate reductase region\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"Sph21_3450 Bifunctional protein folD\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Sph21_2384 phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"Sph21_2382 phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Sph21_1168 Aminomethyltransferase\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"Sph21_0379 methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]"
				},
				{
					"name":"Sph21_2973 Thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"Sph21_1646 formyltetrahydrofolate deformylase\tK01433 purU; formyltetrahydrofolate deformylase [EC:3.5.1.10]"
				},
				{
					"name":"Sph21_0381 Methylenetetrahydrofolate reductase (NAD(P)H)\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"Sph21_1545 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"Sph21_1577 S-adenosylmethionine synthase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Sph21_1238 Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"Sph21_2084 Glycine dehydrogenase (decarboxylating)\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_2197 Glycine cleavage system H protein\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"Sph21_2928 Cysteine synthase\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"Sph21_4650 Cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				}
				]
			},
			{
				"name":"00830 Retinol metabolism"
			},
			{
				"name":"00860 Porphyrin metabolism [PATH:shg00860]",
				"children":[
				{
					"name":"Sph21_1436 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Sph21_5198 Glutamyl-tRNA reductase\tK02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]"
				},
				{
					"name":"Sph21_5195 Glutamate-1-semialdehyde 2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]"
				},
				{
					"name":"Sph21_5196 Porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
				},
				{
					"name":"Sph21_5197 Porphobilinogen deaminase\tK01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]"
				},
				{
					"name":"Sph21_5244 Uroporphyrinogen III synthase HEM4\tK01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]"
				},
				{
					"name":"Sph21_5191 Uroporphyrinogen decarboxylase\tK01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]"
				},
				{
					"name":"Sph21_3359 Coproporphyrinogen oxidase\tK00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]"
				},
				{
					"name":"Sph21_3524 oxygen-independent coproporphyrinogen III oxidase\tK02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]"
				},
				{
					"name":"Sph21_5190 Conserved hypothetical protein CHP00701\tK08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]"
				},
				{
					"name":"Sph21_1071 Ferrochelatase\tK01772 hemH; protoporphyrin\/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]"
				},
				{
					"name":"Sph21_0556 uroporphyrin-III C-methyltransferase\tK02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]"
				},
				{
					"name":"Sph21_3191 uroporphyrin-III C-methyltransferase\tK02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]"
				},
				{
					"name":"Sph21_3749 hypothetical protein\tK02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]"
				},
				{
					"name":"Sph21_3750 uroporphyrin-III C-methyltransferase\tK02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]"
				},
				{
					"name":"Sph21_1557 Protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"Sph21_1556 cytochrome oxidase assembly\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"Sph21_2114 Magnesium chelatase\tK02230 cobN; cobaltochelatase CobN [EC:6.6.1.2]"
				},
				{
					"name":"Sph21_3515 ATP\/cobalamin adenosyltransferase\tK00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]"
				},
				{
					"name":"Sph21_1185 Mg-chelatase subunit ChlI\tK03405 chlI; magnesium chelatase subunit I [EC:6.6.1.1]"
				}
				]
			},
			{
				"name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:shg00130]",
				"children":[
				{
					"name":"Sph21_5212 4-hydroxybenzoate polyprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]"
				},
				{
					"name":"Sph21_2218 Carboxylyase-related protein\tK03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]"
				},
				{
					"name":"Sph21_5119 3-octaprenyl-4-hydroxybenzoate carboxy-lyase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				},
				{
					"name":"Sph21_5210 Ubiquinone\/menaquinone biosynthesis methyltransferase ubiE\tK03183 ubiE; demethylmenaquinone methyltransferase \/ 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]"
				},
				{
					"name":"Sph21_3377 protein of unknown function DUF178\tK11782 mqnA; chorismate dehydratase [EC:4.2.1.151]"
				},
				{
					"name":"Sph21_3379 putative menaquinone biosynthesis protein\tK18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]"
				},
				{
					"name":"Sph21_1139 amidohydrolase\tK20810 mqnX; aminodeoxyfutalosine deaminase [EC:3.5.4.40]"
				},
				{
					"name":"Sph21_1320 futalosine nucleosidase\tK11783 mqnB; futalosine hydrolase [EC:3.2.2.26]"
				},
				{
					"name":"Sph21_3052 FO synthase, subunit 2\tK11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]"
				},
				{
					"name":"Sph21_1321 protein of unknown function DUF191\tK11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]"
				},
				{
					"name":"Sph21_0974 Ribosyldihydronicotinamide dehydrogenase (quinone)\tK00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]"
				},
				{
					"name":"Sph21_4322 NAD(P)H dehydrogenase (quinone)\tK00355 NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]"
				},
				{
					"name":"Sph21_4192 NmrA family protein\tK19267 qorB; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]"
				}
				]
			}
			]
		},
		{
			"name":"09109 Metabolism of terpenoids and polyketides",
			"children":[
			{
				"name":"00900 Terpenoid backbone biosynthesis [PATH:shg00900]",
				"children":[
				{
					"name":"Sph21_1133 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]"
				},
				{
					"name":"Sph21_2919 1-deoxy-D-xylulose 5-phosphate reductoisomerase\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]"
				},
				{
					"name":"Sph21_3992 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]"
				},
				{
					"name":"Sph21_2977 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]"
				},
				{
					"name":"Sph21_1631 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]"
				},
				{
					"name":"Sph21_2204 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]"
				},
				{
					"name":"Sph21_1072 hydroxymethylbutenyl pyrophosphate reductase\tK03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_5119 3-octaprenyl-4-hydroxybenzoate carboxy-lyase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				},
				{
					"name":"Sph21_3638 Isopentenyl-diphosphate Delta-isomerase\tK01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]"
				},
				{
					"name":"Sph21_3092 Geranyltranstransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"Sph21_1116 Trans-hexaprenyltranstransferase\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]"
				},
				{
					"name":"Sph21_5202 Undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				}
				]
			},
			{
				"name":"00902 Monoterpenoid biosynthesis"
			},
			{
				"name":"00909 Sesquiterpenoid and triterpenoid biosynthesis"
			},
			{
				"name":"00904 Diterpenoid biosynthesis"
			},
			{
				"name":"00906 Carotenoid biosynthesis"
			},
			{
				"name":"00905 Brassinosteroid biosynthesis"
			},
			{
				"name":"00981 Insect hormone biosynthesis"
			},
			{
				"name":"00908 Zeatin biosynthesis"
			},
			{
				"name":"00903 Limonene degradation"
			},
			{
				"name":"00907 Pinene, camphor and geraniol degradation [PATH:shg00907]",
				"children":[
				{
					"name":"Sph21_2967 Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"01052 Type I polyketide structures"
			},
			{
				"name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides"
			},
			{
				"name":"01051 Biosynthesis of ansamycins",
				"children":[
				{
					"name":"Sph21_2191 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2617 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_2618 1-deoxy-D-xylulose-5-phosphate synthase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3915 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"Sph21_3916 Transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				}
				]
			},
			{
				"name":"01059 Biosynthesis of enediyne antibiotics"
			},
			{
				"name":"01056 Biosynthesis of type II polyketide backbone"
			},
			{
				"name":"01057 Biosynthesis of type II polyketide products"
			},
			{
				"name":"00253 Tetracycline biosynthesis"
			},
			{
				"name":"00523 Polyketide sugar unit biosynthesis [PATH:shg00523]",
				"children":[
				{
					"name":"Sph21_1754 glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"Sph21_1049 UDP-glucuronate decarboxylase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1051 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1566 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"Sph21_2081 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"Sph21_2294 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"01054 Nonribosomal peptide structures"
			},
			{
				"name":"01053 Biosynthesis of siderophore group nonribosomal peptides"
			},
			{
				"name":"01055 Biosynthesis of vancomycin group antibiotics",
				"children":[
				{
					"name":"Sph21_1049 UDP-glucuronate decarboxylase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1051 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			}
			]
		},
		{
			"name":"09110 Biosynthesis of other secondary metabolites",
			"children":[
			{
				"name":"00940 Phenylpropanoid biosynthesis"
			},
			{
				"name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis"
			},
			{
				"name":"00941 Flavonoid biosynthesis"
			},
			{
				"name":"00944 Flavone and flavonol biosynthesis"
			},
			{
				"name":"00942 Anthocyanin biosynthesis"
			},
			{
				"name":"00943 Isoflavonoid biosynthesis"
			},
			{
				"name":"00946 Degradation of flavonoids [PATH:shg00946]",
				"children":[
				{
					"name":"Sph21_1423 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3133 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3949 beta-galactosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_0443 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				},
				{
					"name":"Sph21_0444 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				},
				{
					"name":"Sph21_0463 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				},
				{
					"name":"Sph21_2315 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				},
				{
					"name":"Sph21_2325 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				},
				{
					"name":"Sph21_2337 alpha-L-rhamnosidase\tK05989 ramA; alpha-L-rhamnosidase [EC:3.2.1.40]"
				}
				]
			},
			{
				"name":"00901 Indole alkaloid biosynthesis"
			},
			{
				"name":"00403 Indole diterpene alkaloid biosynthesis"
			},
			{
				"name":"00950 Isoquinoline alkaloid biosynthesis"
			},
			{
				"name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis"
			},
			{
				"name":"00996 Biosynthesis of various alkaloids"
			},
			{
				"name":"00232 Caffeine metabolism"
			},
			{
				"name":"00965 Betalain biosynthesis"
			},
			{
				"name":"00966 Glucosinolate biosynthesis"
			},
			{
				"name":"00402 Benzoxazinoid biosynthesis"
			},
			{
				"name":"00311 Penicillin and cephalosporin biosynthesis [PATH:shg00311]",
				"children":[
				{
					"name":"Sph21_0487 Acetyl xylan esterase\tK01060 cah; cephalosporin-C deacetylase [EC:3.1.1.41]"
				},
				{
					"name":"Sph21_3904 peptidase S45 penicillin amidase\tK01434 pac; penicillin G amidase [EC:3.5.1.11]"
				}
				]
			},
			{
				"name":"00332 Carbapenem biosynthesis [PATH:shg00332]",
				"children":[
				{
					"name":"Sph21_3653 Glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"Sph21_3652 Gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				}
				]
			},
			{
				"name":"00261 Monobactam biosynthesis [PATH:shg00261]",
				"children":[
				{
					"name":"Sph21_3195 sulfate adenylyltransferase, large subunit\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_3194 sulfate adenylyltransferase, small subunit\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"Sph21_3171 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_4675 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"Sph21_1430 aspartate kinase\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"Sph21_1075 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"Sph21_0049 Dihydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_2300 dihydrodipicolinate synthetase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_4588 dihydrodipicolinate synthetase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"Sph21_0425 Dihydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				}
				]
			},
			{
				"name":"00331 Clavulanic acid biosynthesis"
			},
			{
				"name":"00521 Streptomycin biosynthesis [PATH:shg00521]",
				"children":[
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_2018 phosphoglucomutase\/phosphomannomutase alpha\/beta\/alpha domain I\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"Sph21_5106 Myo-inositol-1-phosphate synthase\tK01858 INO1; myo-inositol-1-phosphate synthase [EC:5.5.1.4]"
				},
				{
					"name":"Sph21_3623 Inositol-phosphate phosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]"
				},
				{
					"name":"Sph21_1754 glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"Sph21_1049 UDP-glucuronate decarboxylase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1051 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1566 dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"Sph21_2081 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"Sph21_2294 dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"00524 Neomycin, kanamycin and gentamicin biosynthesis",
				"children":[
				{
					"name":"Sph21_5117 glucokinase\tK00845 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"Sph21_1910 ROK family protein\tK25026 glk; glucokinase [EC:2.7.1.2]"
				}
				]
			},
			{
				"name":"00525 Acarbose and validamycin biosynthesis [PATH:shg00525]",
				"children":[
				{
					"name":"Sph21_1754 glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"Sph21_1049 UDP-glucuronate decarboxylase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"Sph21_1051 dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00401 Novobiocin biosynthesis [PATH:shg00401]",
				"children":[
				{
					"name":"Sph21_1605 Prephenate dehydrogenase\tK04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			},
			{
				"name":"00404 Staurosporine biosynthesis"
			},
			{
				"name":"00405 Phenazine biosynthesis",
				"children":[
				{
					"name":"Sph21_1506 Anthranilate synthase\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"Sph21_1507 glutamine amidotransferase of anthranilate synthase\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				}
				]
			},
			{
				"name":"00333 Prodigiosin biosynthesis",
				"children":[
				{
					"name":"Sph21_1317 malonyl CoA-acyl carrier protein transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Sph21_0337 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2365 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2703 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_4360 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_0398 Enoyl-(acyl-carrier-protein) reductase (NADH)\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]"
				}
				]
			},
			{
				"name":"00254 Aflatoxin biosynthesis"
			},
			{
				"name":"00975 Biosynthesis of various siderophores"
			},
			{
				"name":"00998 Biosynthesis of various antibiotics",
				"children":[
				{
					"name":"Sph21_1356 Acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"Sph21_3686 hypothetical protein\tK02078 acpP; acyl carrier protein"
				}
				]
			},
			{
				"name":"00999 Biosynthesis of various plant secondary metabolites [PATH:shg00999]",
				"children":[
				{
					"name":"Sph21_1577 S-adenosylmethionine synthase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"Sph21_1423 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3133 Beta-glucosidase\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"Sph21_3949 beta-galactosidase\tK05350 bglB; beta-glucosidase [EC:3.2.1.21]"
				}
				]
			},
			{
				"name":"00997 Biosynthesis of various other secondary metabolites"
			}
			]
		},
		{
			"name":"09111 Xenobiotics biodegradation and metabolism",
			"children":[
			{
				"name":"00362 Benzoate degradation [PATH:shg00362]",
				"children":[
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"Sph21_0121 Carboxymuconolactone decarboxylase\tK01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]"
				},
				{
					"name":"Sph21_1266 Carboxymuconolactone decarboxylase\tK01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]"
				},
				{
					"name":"Sph21_0021 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"Sph21_2999 Glutaryl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"Sph21_3111 3-hydroxybutyryl-CoA dehydrogenase\tK00074 paaH; 3-hydroxybutyryl-CoA dehydrogenase [EC:1.1.1.157]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00627 Aminobenzoate degradation [PATH:shg00627]",
				"children":[
				{
					"name":"Sph21_1140 Acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"Sph21_5119 3-octaprenyl-4-hydroxybenzoate carboxy-lyase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				}
				]
			},
			{
				"name":"00364 Fluorobenzoate degradation"
			},
			{
				"name":"00625 Chloroalkane and chloroalkene degradation"
			},
			{
				"name":"00361 Chlorocyclohexane and chlorobenzene degradation"
			},
			{
				"name":"00623 Toluene degradation"
			},
			{
				"name":"00622 Xylene degradation"
			},
			{
				"name":"00633 Nitrotoluene degradation [PATH:shg00633]",
				"children":[
				{
					"name":"Sph21_4854 12-oxophytodienoate reductase\tK10680 nemA; N-ethylmaleimide reductase [EC:1.-.-.-]"
				}
				]
			},
			{
				"name":"00642 Ethylbenzene degradation",
				"children":[
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"00643 Styrene degradation"
			},
			{
				"name":"00791 Atrazine degradation"
			},
			{
				"name":"00930 Caprolactam degradation",
				"children":[
				{
					"name":"Sph21_1253 Gluconolactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_4037 SMP-30\/Gluconolaconase\/LRE-like region-containing protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				}
				]
			},
			{
				"name":"00363 Bisphenol degradation"
			},
			{
				"name":"00621 Dioxin degradation"
			},
			{
				"name":"00626 Naphthalene degradation"
			},
			{
				"name":"00624 Polycyclic aromatic hydrocarbon degradation"
			},
			{
				"name":"00365 Furfural degradation"
			},
			{
				"name":"00984 Steroid degradation [PATH:shg00984]",
				"children":[
				{
					"name":"Sph21_0020 acetyl-CoA acetyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"00980 Metabolism of xenobiotics by cytochrome P450"
			},
			{
				"name":"00982 Drug metabolism - cytochrome P450"
			},
			{
				"name":"00983 Drug metabolism - other enzymes"
			}
			]
		},
		{
			"name":"09112 Not included in regular maps",
			"children":[
			{
				"name":"09113 Global maps only"
			}
			]
		}
		]
	},
	{
		"name":"09120 Genetic Information Processing",
		"children":[
		{
			"name":"09121 Transcription",
			"children":[
			{
				"name":"03020 RNA polymerase [PATH:shg03020]",
				"children":[
				{
					"name":"Sph21_2406 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_2407 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_1742 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				}
				]
			},
			{
				"name":"03022 Basal transcription factors"
			},
			{
				"name":"03040 Spliceosome"
			}
			]
		},
		{
			"name":"09122 Translation",
			"children":[
			{
				"name":"03010 Ribosome [PATH:shg03010]",
				"children":[
				{
					"name":"Sph21_R0009 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0034 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0068 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0007 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0013 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0037 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0065 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0038 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0064 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_3134 RNA binding S1 domain protein\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"Sph21_1445 ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"Sph21_1720 ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"Sph21_1741 ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"Sph21_1732 ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"Sph21_2352 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"Sph21_3980 ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"Sph21_1729 ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"Sph21_1446 ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"Sph21_3978 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"Sph21_1740 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"Sph21_3981 ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"Sph21_1739 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"Sph21_1728 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"Sph21_3076 ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"Sph21_1325 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"Sph21_1724 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"Sph21_2351 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"Sph21_1718 ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"Sph21_3959 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"Sph21_2394 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"Sph21_2458 hypothetical protein\tK19033 PSRP4; 30S ribosomal protein S31\/Thx"
				},
				{
					"name":"Sph21_2403 ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"Sph21_1717 ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"Sph21_1714 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"Sph21_1715 ribosomal protein L4\/L1e\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"Sph21_1727 ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"Sph21_1730 ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"Sph21_2350 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"Sph21_2404 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"Sph21_2402 ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"Sph21_2405 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"Sph21_1447 ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"Sph21_1725 ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"Sph21_1734 ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"Sph21_1721 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"Sph21_1743 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"Sph21_1731 ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"Sph21_1328 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"Sph21_2966 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"Sph21_3305 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"Sph21_1719 ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"Sph21_1716 Ribosomal protein L25\/L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"Sph21_1726 ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"Sph21_5155 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"Sph21_3306 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"Sph21_5182 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"Sph21_1723 ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"Sph21_1733 ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"Sph21_3043 50S ribosomal protein L31 type B\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"Sph21_0009 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"Sph21_5183 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"Sph21_0328 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"Sph21_2965 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"Sph21_1738 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36"
				}
				]
			},
			{
				"name":"00970 Aminoacyl-tRNA biosynthesis [PATH:shg00970]",
				"children":[
				{
					"name":"Sph21_R0023 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0036 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0066 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0003 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0020 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0049 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0021 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"Sph21_R0018 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Sph21_R0019 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Sph21_R0022 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0046 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0058 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0062 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0063 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Sph21_R0004 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Sph21_R0005 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Sph21_R0028 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0055 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0060 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0033 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"Sph21_R0008 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0014 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0035 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0067 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0040 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0053 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0054 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0061 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0050 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0051 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0052 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0010 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0011 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0025 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"Sph21_R0016 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0017 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0057 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0059 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0031 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0039 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0043 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0056 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0026 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0029 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0042 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0030 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"Sph21_R0027 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"Sph21_R0001 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_R0002 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_R0032 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_1436 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Sph21_0772 Glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Sph21_3106 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Sph21_1132 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Sph21_3337 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Sph21_1705 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Sph21_2963 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Sph21_5220 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Sph21_2962 L-seryl-tRNA(ser) selenium transferase protein\tK01042 selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]"
				},
				{
					"name":"Sph21_1472 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Sph21_1427 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Sph21_3548 Methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]"
				},
				{
					"name":"Sph21_2462 Valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Sph21_0546 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Sph21_0041 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Sph21_2410 Lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"Sph21_3007 Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Sph21_4651 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Sph21_1306 Histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Sph21_1460 Phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3955 Phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3907 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Sph21_3512 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"03013 Nucleocytoplasmic transport"
			},
			{
				"name":"03015 mRNA surveillance pathway"
			},
			{
				"name":"03008 Ribosome biogenesis in eukaryotes",
				"children":[
				{
					"name":"Sph21_1358 Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			}
			]
		},
		{
			"name":"09123 Folding, sorting and degradation",
			"children":[
			{
				"name":"03060 Protein export [PATH:shg03060]",
				"children":[
				{
					"name":"Sph21_1735 preprotein translocase, SecY subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Sph21_2400 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Sph21_0751 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Sph21_2971 protein-export membrane protein SecD\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"Sph21_4005 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Sph21_3520 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Sph21_0674 Protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Sph21_1442 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Sph21_R0045 ffs; SRP RNA; RNA component of signal recognition particle\tK01983 ffs; signal recognition particle 4.5S RNA"
				},
				{
					"name":"Sph21_5185 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Sph21_1145 twin-arginine translocation protein, TatA\/E family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2075 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2540 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_0014 Sec-independent protein translocase, TatC subunit\tK03118 tatC; sec-independent protein translocase protein TatC"
				},
				{
					"name":"Sph21_0424 signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"Sph21_0043 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"Sph21_2364 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				}
				]
			},
			{
				"name":"04141 Protein processing in endoplasmic reticulum [PATH:shg04141]",
				"children":[
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_0002 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Sph21_2858 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Sph21_3240 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				}
				]
			},
			{
				"name":"04130 SNARE interactions in vesicular transport"
			},
			{
				"name":"04120 Ubiquitin mediated proteolysis"
			},
			{
				"name":"04122 Sulfur relay system [PATH:shg04122]",
				"children":[
				{
					"name":"Sph21_3019 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3741 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3997 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3175 tRNA-specific 2-thiouridylase mnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"Sph21_0143 molybdopterin biosynthesis MoaE protein\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]"
				},
				{
					"name":"Sph21_5098 molybdopterin biosynthesis MoaE protein\tK03635 MOCS2B; molybdopterin synthase catalytic subunit [EC:2.8.1.12]"
				},
				{
					"name":"Sph21_3738 molybdenum cofactor biosynthesis protein A\tK03639 moaA; GTP 3',8-cyclase [EC:4.1.99.22]"
				},
				{
					"name":"Sph21_3735 thiamineS protein\tK03636 moaD; sulfur-carrier protein"
				},
				{
					"name":"Sph21_1382 UBA\/THIF-type NAD\/FAD binding protein\tK21147 moeZR; sulfur-carrier protein adenylyltransferase\/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-]"
				},
				{
					"name":"Sph21_3734 UBA\/THIF-type NAD\/FAD binding protein\tK21147 moeZR; sulfur-carrier protein adenylyltransferase\/sulfurtransferase [EC:2.7.7.80 2.7.7.- 2.8.1.11 2.8.1.-]"
				},
				{
					"name":"Sph21_1388 thiamine biosynthesis protein ThiS\tK03154 thiS; sulfur carrier protein"
				}
				]
			},
			{
				"name":"03050 Proteasome"
			},
			{
				"name":"03018 RNA degradation [PATH:shg03018]",
				"children":[
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Sph21_3088 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"Sph21_0774 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3518 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3885 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3093 ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"Sph21_3878 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_2937 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3364 ATP-dependent DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_4019 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"Sph21_3952 2,3 cyclic-nucleotide 2-phosphodiesterase\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Sph21_0532 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_3169 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_2713 polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]"
				},
				{
					"name":"Sph21_2425 polynucleotide adenylyltransferase\/metal dependent phosphohydrolase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"09124 Replication and repair",
			"children":[
			{
				"name":"03030 DNA replication [PATH:shg03030]",
				"children":[
				{
					"name":"Sph21_3055 Exonuclease RNase T and DNA polymerase III\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3431 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3922 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2353 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0763 DNA polymerase III gamma\/tau subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2465 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1712 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3056 replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"Sph21_0670 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_3294 Ribonuclease H\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"Sph21_1167 Ribonuclease H\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03410 Base excision repair [PATH:shg03410]",
				"children":[
				{
					"name":"Sph21_0570 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Sph21_4011 Uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"Sph21_1130 A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"Sph21_2724 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
				},
				{
					"name":"Sph21_3236 DNA-formamidopyrimidine glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
				},
				{
					"name":"Sph21_5115 HhH-GPD family protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				},
				{
					"name":"Sph21_1495 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_4366 methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_4849 methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_1390 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Sph21_4521 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0716 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03420 Nucleotide excision repair [PATH:shg03420]",
				"children":[
				{
					"name":"Sph21_1343 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_0558 excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Sph21_5270 excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Sph21_0721 UvrABC system protein B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"Sph21_5241 UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"Sph21_2931 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3839 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03430 Mismatch repair [PATH:shg03430]",
				"children":[
				{
					"name":"Sph21_3063 DNA mismatch repair protein mutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Sph21_5111 DNA mismatch repair protein MutS domain protein\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Sph21_4670 MutS2 protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"Sph21_1476 DNA mismatch repair protein mutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"Sph21_2931 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3839 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_1456 Exonuclease VII, large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"Sph21_1455 Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"Sph21_0716 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_3922 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1712 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2353 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2465 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0763 DNA polymerase III gamma\/tau subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3055 Exonuclease RNase T and DNA polymerase III\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3431 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03440 Homologous recombination [PATH:shg03440]",
				"children":[
				{
					"name":"Sph21_0716 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5257 DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"Sph21_0038 DNA repair protein recO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"Sph21_3097 Recombination protein recR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"Sph21_0569 Protein recA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2087 Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"Sph21_2470 Holliday junction ATP-dependent DNA helicase ruvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_1573 Crossover junction endodeoxyribonuclease ruvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"Sph21_1158 ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3922 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1712 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2353 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2465 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0763 DNA polymerase III gamma\/tau subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3055 Exonuclease RNase T and DNA polymerase III\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3431 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0322 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03450 Non-homologous end-joining [PATH:shg03450]",
				"children":[
				{
					"name":"Sph21_3426 DNA repair protein\tK10979 ku; DNA end-binding protein Ku"
				},
				{
					"name":"Sph21_2578 DNA ligase D\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
				}
				]
			},
			{
				"name":"03460 Fanconi anemia pathway"
			}
			]
		},
		{
			"name":"09126 Chromosome",
			"children":[
			{
				"name":"03082 ATP-dependent chromatin remodeling"
			},
			{
				"name":"03083 Polycomb repressive complex"
			}
			]
		},
		{
			"name":"09125 Information processing in viruses",
			"children":[
			{
				"name":"03230 Viral genome structure"
			},
			{
				"name":"03240 Viral replication"
			},
			{
				"name":"03250 Viral life cycle - HIV-1"
			},
			{
				"name":"03260 Virion - Human immunodeficiency virus"
			},
			{
				"name":"03271 Virion - Rotavirus"
			},
			{
				"name":"03262 Virion - Coronavirus"
			},
			{
				"name":"03261 Virion - Influenza virus"
			},
			{
				"name":"03263 Virion - Enterovirus"
			},
			{
				"name":"03264 Virion - Flavivirus and Alphavirus"
			},
			{
				"name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus"
			},
			{
				"name":"03273 Virion - Lassa virus and SFTS virus"
			},
			{
				"name":"03272 Virion - Hepatitis viruses",
				"children":[
				{
					"name":"Sph21_0993 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_2473 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				}
				]
			},
			{
				"name":"03266 Virion - Herpesvirus"
			},
			{
				"name":"03268 Virion - Orthopoxvirus"
			},
			{
				"name":"03267 Virion - Adenovirus"
			},
			{
				"name":"03259 Virion - Bacteriophages T4 and T7"
			},
			{
				"name":"03258 Virion - Bacteriophage lambda"
			}
			]
		}
		]
	},
	{
		"name":"09130 Environmental Information Processing",
		"children":[
		{
			"name":"09131 Membrane transport",
			"children":[
			{
				"name":"02010 ABC transporters [PATH:shg02010]",
				"children":[
				{
					"name":"Sph21_2284 ABC transporter related protein\tK05776 modF; molybdate transport system ATP-binding protein"
				},
				{
					"name":"Sph21_0814 ABC-type glycine betaine transport, periplasmic subunit\tK02002 proX; glycine betaine\/proline transport system substrate-binding protein"
				},
				{
					"name":"Sph21_0815 ABC-type transporter, integral membrane subunit\tK02001 proW; glycine betaine\/proline transport system permease protein"
				},
				{
					"name":"Sph21_0816 glycine betaine\/L-proline ABC transporter, ATPase subunit\tK02000 proV; glycine betaine\/proline transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"Sph21_2567 ABC-type glycine betaine transport, periplasmic subunit\tK05845 opuC; osmoprotectant transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2568 Fe(3+)-transporting ATPase\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"Sph21_2534 Mammalian cell entry related domain protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"Sph21_3069 Mammalian cell entry related domain protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"Sph21_1668 protein of unknown function DUF140\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"Sph21_3067 protein of unknown function DUF140\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"Sph21_1667 Sulfate-transporting ATPase\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3068 Sulfate-transporting ATPase\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"Sph21_2619 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2622 ABC-type transporter, integral membrane subunit\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Sph21_2621 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Sph21_4532 ABC-type phosphate transporter substrate-binding component\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4735 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4531 phosphate ABC transporter, inner membrane subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4734 phosphate ABC transporter, inner membrane subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4530 ABC-type transporter, integral membrane subunit\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4733 phosphate ABC transporter, inner membrane subunit PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4529 Phosphate-transporting ATPase\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Sph21_4732 phosphate ABC transporter, ATPase subunit\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Sph21_4537 lipoprotein, YaeC family\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4538 ABC-type transporter, integral membrane subunit\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"Sph21_4539 Phosphonate-transporting ATPase\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"Sph21_1342 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Sph21_3547 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Sph21_3281 Polyamine-transporting ATPase\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Sph21_2981 cytochrome c assembly protein\tK02195 ccmC; heme exporter protein C"
				},
				{
					"name":"Sph21_2980 cytochrome c-type biogenesis protein CcmB\tK02194 ccmB; heme exporter protein B"
				},
				{
					"name":"Sph21_0564 permease YjgP\/YjgQ family protein\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Sph21_2520 permease YjgP\/YjgQ family protein\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Sph21_0715 Sulfate-transporting ATPase\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Sph21_4999 ABC transporter related protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Sph21_0547 protein of unknown function DUF214\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"Sph21_3122 Sigma 54 interacting domain protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"Sph21_4436 Xenobiotic-transporting ATPase\tK14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA\/YbtP [EC:7.-.-.-]"
				},
				{
					"name":"Sph21_4435 Xenobiotic-transporting ATPase\tK14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB\/YbtQ [EC:7.-.-.-]"
				},
				{
					"name":"Sph21_1607 Xenobiotic-transporting ATPase\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]"
				},
				{
					"name":"Sph21_4009 Xenobiotic-transporting ATPase\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Sph21_2417 Xenobiotic-transporting ATPase\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Sph21_0591 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1895 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_4095 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				}
				]
			},
			{
				"name":"02060 Phosphotransferase system (PTS)"
			},
			{
				"name":"03070 Bacterial secretion system [PATH:shg03070]",
				"children":[
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_2971 protein-export membrane protein SecD\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"Sph21_2400 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Sph21_0751 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Sph21_1735 preprotein translocase, SecY subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Sph21_4005 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Sph21_3520 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Sph21_0674 Protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Sph21_5185 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Sph21_1442 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Sph21_1145 twin-arginine translocation protein, TatA\/E family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2075 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2540 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_0014 Sec-independent protein translocase, TatC subunit\tK03118 tatC; sec-independent protein translocase protein TatC"
				}
				]
			}
			]
		},
		{
			"name":"09132 Signal transduction",
			"children":[
			{
				"name":"02020 Two-component system [PATH:shg02020]",
				"children":[
				{
					"name":"Sph21_1333 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1369 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4070 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1570 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Sph21_3108 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_4532 ABC-type phosphate transporter substrate-binding component\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4735 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_1406 protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_3618 peptidase S1 and S6 chymotrypsin\/Hap\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_0287 outer membrane protein-like protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2804 outer membrane protein-like protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0285 efflux transporter, RND family, MFP subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0286 hypothetical protein\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2802 efflux transporter, RND family, MFP subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2803 hypothetical protein\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0288 acriflavin resistance protein\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"Sph21_2805 acriflavin resistance protein\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"Sph21_4258 Osmosensitive K channel His kinase sensor\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4254 Potassium-transporting ATPase A chain\tK01546 kdpA; potassium-transporting ATPase potassium-binding subunit"
				},
				{
					"name":"Sph21_4255 Potassium-transporting ATPase B chain\tK01547 kdpB; potassium-transporting ATPase ATP-binding subunit [EC:7.2.2.6]"
				},
				{
					"name":"Sph21_4256 Potassium-transporting ATPase C chain\tK01548 kdpC; potassium-transporting ATPase KdpC subunit"
				},
				{
					"name":"Sph21_1556 cytochrome oxidase assembly\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"Sph21_0001 Chromosomal replication initiator protein dnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Sph21_4054 Lysylphosphatidylglycerol synthetase\/UPF0104\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				},
				{
					"name":"Sph21_0696 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"Sph21_1090 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"Sph21_4476 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"Sph21_4504 response regulator receiver sensor signal transduction histidine kinase\tK07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2076 integral membrane sensor signal transduction histidine kinase\tK07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4952 response regulator receiver protein\tK07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB"
				},
				{
					"name":"Sph21_2093 two component transcriptional regulator, LuxR family\tK07689 uvrY; two-component system, NarL family, invasion response regulator UvrY"
				},
				{
					"name":"Sph21_3744 two component transcriptional regulator, LuxR family\tK07692 degU; two-component system, NarL family, response regulator DegU"
				},
				{
					"name":"Sph21_3206 two component transcriptional regulator, LuxR family\tK07696 nreC; two-component system, NarL family, response regulator NreC"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_1172 two component, sigma54 specific, transcriptional regulator, Fis family\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"Sph21_3147 two component, sigma54 specific, transcriptional regulator, Fis family\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_1231 sodium:dicarboxylate symporter\tK11103 dctA; aerobic C4-dicarboxylate transport protein"
				},
				{
					"name":"Sph21_0330 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"Sph21_4259 multi-sensor signal transduction histidine kinase\tK11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1115 MCP methyltransferase, CheR-type\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"Sph21_2156 signal transduction histidine kinase with CheB and CheR activity\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]"
				},
				{
					"name":"Sph21_2096 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2923 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2157 putative PAS\/PAC sensor protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4914 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Sph21_3527 cytochrome c oxidase, cbb3-type, subunit I\tK15862 ccoNO; cytochrome c oxidase cbb3-type subunit I\/II [EC:7.1.1.9]"
				},
				{
					"name":"Sph21_3529 cytochrome c class I\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III"
				},
				{
					"name":"Sph21_1182 cytochrome bd ubiquinol oxidase subunit I\tK00425 cydA; cytochrome bd ubiquinol oxidase subunit I [EC:7.1.1.7]"
				},
				{
					"name":"Sph21_1183 cytochrome bd ubiquinol oxidase subunit II\tK00426 cydB; cytochrome bd ubiquinol oxidase subunit II [EC:7.1.1.7]"
				},
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1809 Soluble ligand binding domain\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_1958 polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_2025 Soluble ligand binding domain\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_1170 protein tyrosine phosphatase\tK25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"Sph21_1810 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_1959 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_2026 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_1828 UDP-N-acetylglucosamine 2-epimerase\tK01791 wecB; UDP-N-acetylglucosamine 2-epimerase (non-hydrolysing) [EC:5.1.3.14]"
				},
				{
					"name":"Sph21_2881 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				},
				{
					"name":"Sph21_2885 Pectinesterase\tK01051 E3.1.1.11; pectinesterase [EC:3.1.1.11]"
				},
				{
					"name":"Sph21_4498 glycoside hydrolase family 5\tK01179 E3.2.1.4; endoglucanase [EC:3.2.1.4]"
				},
				{
					"name":"Sph21_0462 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0486 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0805 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0806 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0843 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0972 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1281 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1664 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1778 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1869 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1877 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1890 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1918 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1965 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2264 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2492 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2497 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2764 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2833 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2938 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2954 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_3403 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4232 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4293 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4311 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4413 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4695 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4805 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4857 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_5020 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0938 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_0999 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_1663 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_1878 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_1966 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_2769 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_2778 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4233 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4310 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4334 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4414 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4696 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_4858 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"Sph21_5019 anti-FecI sigma factor, FecR\tK07165 fecR; transmembrane sensor"
				}
				]
			},
			{
				"name":"04010 MAPK signaling pathway"
			},
			{
				"name":"04013 MAPK signaling pathway - fly"
			},
			{
				"name":"04016 MAPK signaling pathway - plant"
			},
			{
				"name":"04011 MAPK signaling pathway - yeast"
			},
			{
				"name":"04012 ErbB signaling pathway"
			},
			{
				"name":"04014 Ras signaling pathway"
			},
			{
				"name":"04015 Rap1 signaling pathway"
			},
			{
				"name":"04310 Wnt signaling pathway"
			},
			{
				"name":"04330 Notch signaling pathway"
			},
			{
				"name":"04340 Hedgehog signaling pathway"
			},
			{
				"name":"04341 Hedgehog signaling pathway - fly"
			},
			{
				"name":"04350 TGF-beta signaling pathway"
			},
			{
				"name":"04390 Hippo signaling pathway"
			},
			{
				"name":"04391 Hippo signaling pathway - fly"
			},
			{
				"name":"04392 Hippo signaling pathway - multiple species"
			},
			{
				"name":"04370 VEGF signaling pathway"
			},
			{
				"name":"04371 Apelin signaling pathway"
			},
			{
				"name":"04630 JAK-STAT signaling pathway"
			},
			{
				"name":"04064 NF-kappa B signaling pathway"
			},
			{
				"name":"04668 TNF signaling pathway"
			},
			{
				"name":"04066 HIF-1 signaling pathway"
			},
			{
				"name":"04068 FoxO signaling pathway"
			},
			{
				"name":"04020 Calcium signaling pathway"
			},
			{
				"name":"04070 Phosphatidylinositol signaling system"
			},
			{
				"name":"04072 Phospholipase D signaling pathway"
			},
			{
				"name":"04071 Sphingolipid signaling pathway"
			},
			{
				"name":"04024 cAMP signaling pathway"
			},
			{
				"name":"04022 cGMP-PKG signaling pathway"
			},
			{
				"name":"04151 PI3K-Akt signaling pathway"
			},
			{
				"name":"04152 AMPK signaling pathway"
			},
			{
				"name":"04150 mTOR signaling pathway"
			},
			{
				"name":"04075 Plant hormone signal transduction"
			}
			]
		},
		{
			"name":"09133 Signaling molecules and interaction",
			"children":[
			{
				"name":"04080 Neuroactive ligand-receptor interaction"
			},
			{
				"name":"04082 Neuroactive ligand signaling"
			},
			{
				"name":"04081 Hormone signaling"
			},
			{
				"name":"04060 Cytokine-cytokine receptor interaction"
			},
			{
				"name":"04061 Viral protein interaction with cytokine and cytokine receptor"
			},
			{
				"name":"04512 ECM-receptor interaction"
			},
			{
				"name":"04514 Cell adhesion molecule (CAM) interaction"
			},
			{
				"name":"04517 IgSF CAM signaling"
			},
			{
				"name":"04518 Integrin signaling"
			},
			{
				"name":"04519 Cadherin signaling"
			}
			]
		}
		]
	},
	{
		"name":"09140 Cellular Processes",
		"children":[
		{
			"name":"09141 Transport and catabolism",
			"children":[
			{
				"name":"04144 Endocytosis"
			},
			{
				"name":"04145 Phagocytosis",
				"children":[
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				}
				]
			},
			{
				"name":"04142 Lysosome biogenesis [PATH:shg04142]",
				"children":[
				{
					"name":"Sph21_0395 Sulphatase-modifying factor protein\tK13444 SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]"
				},
				{
					"name":"Sph21_2007 Sulphatase-modifying factor protein\tK13444 SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]"
				},
				{
					"name":"Sph21_2358 Glucan endo-1,6-beta-glucosidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"Sph21_0603 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0657 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0729 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_1768 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2056 coagulation factor 5\/8 type domain protein\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2166 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2860 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2863 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2868 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3373 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3374 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4700 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4801 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0646 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0655 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0656 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1083 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_3771 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_4587 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_4589 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_5174 glycosyl hydrolase BNR repeat-containing protein\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"Sph21_4218 Iduronate-2-sulfatase\tK01136 IDS; iduronate 2-sulfatase [EC:3.1.6.13]"
				},
				{
					"name":"Sph21_5173 Iduronate-2-sulfatase\tK01136 IDS; iduronate 2-sulfatase [EC:3.1.6.13]"
				},
				{
					"name":"Sph21_0941 N-sulfoglucosamine sulfohydrolase\tK01565 SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]"
				},
				{
					"name":"Sph21_4315 N-sulfoglucosamine sulfohydrolase\tK01565 SGSH; N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1]"
				},
				{
					"name":"Sph21_3890 N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase\tK01444 AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]"
				}
				]
			},
			{
				"name":"04146 Peroxisome [PATH:shg04146]",
				"children":[
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_0366 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_3146 isocitrate dehydrogenase, NADP-dependent\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"Sph21_2967 Hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"Sph21_1533 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_4886 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_5077 Catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_1066 Superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]"
				},
				{
					"name":"Sph21_4297 Superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]"
				}
				]
			},
			{
				"name":"04149 Peroxisome - yeast"
			},
			{
				"name":"04140 Autophagy - animal"
			},
			{
				"name":"04138 Autophagy - yeast"
			},
			{
				"name":"04136 Autophagy - other"
			},
			{
				"name":"04137 Mitophagy - animal"
			},
			{
				"name":"04139 Mitophagy - yeast"
			},
			{
				"name":"04148 Efferocytosis",
				"children":[
				{
					"name":"Sph21_2761 Arginase\/agmatinase\/formiminoglutamase\tK01476 rocF; arginase [EC:3.5.3.1]"
				}
				]
			}
			]
		},
		{
			"name":"09143 Cell growth and death",
			"children":[
			{
				"name":"04110 Cell cycle"
			},
			{
				"name":"04111 Cell cycle - yeast"
			},
			{
				"name":"04112 Cell cycle - Caulobacter"
			},
			{
				"name":"04113 Meiosis - yeast"
			},
			{
				"name":"04114 Oocyte meiosis"
			},
			{
				"name":"04210 Apoptosis"
			},
			{
				"name":"04214 Apoptosis - fly"
			},
			{
				"name":"04215 Apoptosis - multiple species"
			},
			{
				"name":"04216 Ferroptosis"
			},
			{
				"name":"04217 Necroptosis"
			},
			{
				"name":"04115 p53 signaling pathway"
			},
			{
				"name":"04218 Cellular senescence"
			},
			{
				"name":"04156 Integrated stress response (ISR) signaling pathway [PATH:shg04156]",
				"children":[
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_R0010 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0011 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				}
				]
			}
			]
		},
		{
			"name":"09144 Cellular community - eukaryotes",
			"children":[
			{
				"name":"04510 Focal adhesion"
			},
			{
				"name":"04520 Adherens junction"
			},
			{
				"name":"04530 Tight junction"
			},
			{
				"name":"04540 Gap junction"
			},
			{
				"name":"04550 Signaling pathways regulating pluripotency of stem cells"
			}
			]
		},
		{
			"name":"09145 Cellular community - prokaryotes",
			"children":[
			{
				"name":"02024 Quorum sensing [PATH:shg02024]",
				"children":[
				{
					"name":"Sph21_1506 Anthranilate synthase\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"Sph21_1507 glutamine amidotransferase of anthranilate synthase\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_4914 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Sph21_0933 Endoglucanase H\/Glycosyl hydrolase family 26\tK01218 gmuG; mannan endo-1,4-beta-mannosidase [EC:3.2.1.78]"
				},
				{
					"name":"Sph21_3390 riboflavin biosynthesis protein RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]"
				},
				{
					"name":"Sph21_0423 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1488 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2599 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2826 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4896 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0591 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1895 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_4095 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1896 secretion protein HlyD family protein\tK20345 blpB; membrane fusion protein, peptide pheromone\/bacteriocin exporter"
				},
				{
					"name":"Sph21_4094 secretion protein HlyD family protein\tK20345 blpB; membrane fusion protein, peptide pheromone\/bacteriocin exporter"
				},
				{
					"name":"Sph21_3520 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Sph21_2971 protein-export membrane protein SecD\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"Sph21_2400 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Sph21_0751 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Sph21_1735 preprotein translocase, SecY subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Sph21_4005 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Sph21_0674 Protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Sph21_5185 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Sph21_1442 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Sph21_3744 two component transcriptional regulator, LuxR family\tK07692 degU; two-component system, NarL family, response regulator DegU"
				},
				{
					"name":"Sph21_0662 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_1769 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_0696 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"Sph21_1090 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"Sph21_4476 Lantibiotic dehydratase domain protein\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				}
				]
			},
			{
				"name":"05111 Biofilm formation - Vibrio cholerae"
			},
			{
				"name":"02025 Biofilm formation - Pseudomonas aeruginosa"
			},
			{
				"name":"02026 Biofilm formation - Escherichia coli"
			}
			]
		},
		{
			"name":"09142 Cell motility",
			"children":[
			{
				"name":"02030 Bacterial chemotaxis [PATH:shg02030]",
				"children":[
				{
					"name":"Sph21_2619 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2096 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2923 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2156 signal transduction histidine kinase with CheB and CheR activity\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]"
				},
				{
					"name":"Sph21_1115 MCP methyltransferase, CheR-type\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				}
				]
			},
			{
				"name":"02040 Flagellar assembly [PATH:shg02040]",
				"children":[
				{
					"name":"Sph21_3256 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Sph21_4481 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Sph21_0330 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				}
				]
			},
			{
				"name":"04814 Motor proteins"
			},
			{
				"name":"04820 Cytoskeleton in muscle cells",
				"children":[
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				}
				]
			},
			{
				"name":"04810 Regulation of actin cytoskeleton"
			}
			]
		}
		]
	},
	{
		"name":"09150 Organismal Systems",
		"children":[
		{
			"name":"09151 Immune system",
			"children":[
			{
				"name":"04640 Hematopoietic cell lineage"
			},
			{
				"name":"04610 Complement and coagulation cascades"
			},
			{
				"name":"04611 Platelet activation"
			},
			{
				"name":"04613 Neutrophil extracellular trap formation"
			},
			{
				"name":"04620 Toll-like receptor signaling pathway"
			},
			{
				"name":"04624 Toll and Imd signaling pathway"
			},
			{
				"name":"04621 NOD-like receptor signaling pathway"
			},
			{
				"name":"04622 RIG-I-like receptor signaling pathway"
			},
			{
				"name":"04623 Cytosolic DNA-sensing pathway"
			},
			{
				"name":"04625 C-type lectin receptor signaling pathway"
			},
			{
				"name":"04650 Natural killer cell mediated cytotoxicity"
			},
			{
				"name":"04612 Antigen processing and presentation"
			},
			{
				"name":"04660 T cell receptor signaling pathway"
			},
			{
				"name":"04658 Th1 and Th2 cell differentiation"
			},
			{
				"name":"04659 Th17 cell differentiation"
			},
			{
				"name":"04657 IL-17 signaling pathway"
			},
			{
				"name":"04662 B cell receptor signaling pathway"
			},
			{
				"name":"04664 Fc epsilon RI signaling pathway"
			},
			{
				"name":"04666 Fc gamma R-mediated phagosome formation"
			},
			{
				"name":"04670 Leukocyte transendothelial migration"
			},
			{
				"name":"04672 Intestinal immune network for IgA production"
			},
			{
				"name":"04062 Chemokine signaling pathway"
			}
			]
		},
		{
			"name":"09152 Endocrine system",
			"children":[
			{
				"name":"04911 Insulin secretion"
			},
			{
				"name":"04910 Insulin signaling pathway"
			},
			{
				"name":"04922 Glucagon signaling pathway"
			},
			{
				"name":"04923 Regulation of lipolysis in adipocytes"
			},
			{
				"name":"04920 Adipocytokine signaling pathway"
			},
			{
				"name":"03320 PPAR signaling pathway"
			},
			{
				"name":"04929 GnRH secretion"
			},
			{
				"name":"04912 GnRH signaling pathway"
			},
			{
				"name":"04913 Ovarian steroidogenesis"
			},
			{
				"name":"04915 Estrogen signaling pathway"
			},
			{
				"name":"04914 Progesterone-mediated oocyte maturation"
			},
			{
				"name":"04917 Prolactin signaling pathway"
			},
			{
				"name":"04921 Oxytocin signaling pathway"
			},
			{
				"name":"04926 Relaxin signaling pathway"
			},
			{
				"name":"04935 Growth hormone synthesis, secretion and action"
			},
			{
				"name":"04918 Thyroid hormone synthesis"
			},
			{
				"name":"04919 Thyroid hormone signaling pathway"
			},
			{
				"name":"04928 Parathyroid hormone synthesis, secretion and action"
			},
			{
				"name":"04916 Melanogenesis"
			},
			{
				"name":"04924 Renin secretion"
			},
			{
				"name":"04614 Renin-angiotensin system"
			},
			{
				"name":"04925 Aldosterone synthesis and secretion"
			},
			{
				"name":"04927 Cortisol synthesis and secretion"
			}
			]
		},
		{
			"name":"09153 Circulatory system",
			"children":[
			{
				"name":"04260 Cardiac muscle contraction"
			},
			{
				"name":"04261 Adrenergic signaling in cardiomyocytes"
			},
			{
				"name":"04270 Vascular smooth muscle contraction"
			}
			]
		},
		{
			"name":"09154 Digestive system",
			"children":[
			{
				"name":"04970 Salivary secretion"
			},
			{
				"name":"04971 Gastric acid secretion"
			},
			{
				"name":"04972 Pancreatic secretion"
			},
			{
				"name":"04976 Bile secretion"
			},
			{
				"name":"04973 Carbohydrate digestion and absorption"
			},
			{
				"name":"04974 Protein digestion and absorption"
			},
			{
				"name":"04975 Fat digestion and absorption"
			},
			{
				"name":"04979 Cholesterol metabolism"
			},
			{
				"name":"04977 Vitamin digestion and absorption"
			},
			{
				"name":"04981 Folate transport and metabolism [PATH:shg04981]",
				"children":[
				{
					"name":"Sph21_1545 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"Sph21_2972 dihydrofolate reductase region\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"Sph21_1135 Glycine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"Sph21_2973 Thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"Sph21_0379 methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]"
				}
				]
			},
			{
				"name":"04980 Cobalamin transport and metabolism [PATH:shg04980]",
				"children":[
				{
					"name":"Sph21_3515 ATP\/cobalamin adenosyltransferase\tK00798 MMAB; cob(I)alamin adenosyltransferase [EC:2.5.1.17]"
				},
				{
					"name":"Sph21_0379 methionine synthase\tK00548 metH; 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]"
				}
				]
			},
			{
				"name":"04978 Mineral absorption"
			}
			]
		},
		{
			"name":"09155 Excretory system",
			"children":[
			{
				"name":"04962 Vasopressin-regulated water reabsorption"
			},
			{
				"name":"04960 Aldosterone-regulated sodium reabsorption"
			},
			{
				"name":"04961 Endocrine and other factor-regulated calcium reabsorption"
			},
			{
				"name":"04964 Proximal tubule bicarbonate reclamation"
			},
			{
				"name":"04966 Collecting duct acid secretion"
			}
			]
		},
		{
			"name":"09156 Nervous system",
			"children":[
			{
				"name":"04724 Glutamatergic synapse"
			},
			{
				"name":"04727 GABAergic synapse"
			},
			{
				"name":"04725 Cholinergic synapse"
			},
			{
				"name":"04728 Dopaminergic synapse"
			},
			{
				"name":"04726 Serotonergic synapse"
			},
			{
				"name":"04720 Long-term potentiation"
			},
			{
				"name":"04730 Long-term depression"
			},
			{
				"name":"04723 Retrograde endocannabinoid signaling"
			},
			{
				"name":"04721 Synaptic vesicle cycle"
			},
			{
				"name":"04722 Neurotrophin signaling pathway"
			}
			]
		},
		{
			"name":"09157 Sensory system",
			"children":[
			{
				"name":"04744 Phototransduction"
			},
			{
				"name":"04745 Phototransduction - fly"
			},
			{
				"name":"04740 Olfactory transduction"
			},
			{
				"name":"04742 Taste transduction"
			},
			{
				"name":"04750 Inflammatory mediator regulation of TRP channels"
			}
			]
		},
		{
			"name":"09158 Development and regeneration",
			"children":[
			{
				"name":"04320 Dorso-ventral axis formation"
			},
			{
				"name":"04360 Axon guidance"
			},
			{
				"name":"04361 Axon regeneration"
			},
			{
				"name":"04380 Osteoclast differentiation"
			},
			{
				"name":"04382 Cornified envelope formation [PATH:shg04382]",
				"children":[
				{
					"name":"Sph21_3026 Glycine C-acetyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"Sph21_2358 Glucan endo-1,6-beta-glucosidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"Sph21_5158 peptidase C1A papain\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"Sph21_3303 histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				}
				]
			}
			]
		},
		{
			"name":"09149 Aging",
			"children":[
			{
				"name":"04211 Longevity regulating pathway"
			},
			{
				"name":"04212 Longevity regulating pathway - worm"
			},
			{
				"name":"04213 Longevity regulating pathway - multiple species"
			}
			]
		},
		{
			"name":"09159 Environmental adaptation",
			"children":[
			{
				"name":"04710 Circadian rhythm"
			},
			{
				"name":"04713 Circadian entrainment"
			},
			{
				"name":"04711 Circadian rhythm - fly"
			},
			{
				"name":"04712 Circadian rhythm - plant"
			},
			{
				"name":"04714 Thermogenesis"
			},
			{
				"name":"04626 Plant-pathogen interaction"
			}
			]
		}
		]
	},
	{
		"name":"09160 Human Diseases",
		"children":[
		{
			"name":"09161 Cancer: overview",
			"children":[
			{
				"name":"05200 Pathways in cancer"
			},
			{
				"name":"05202 Transcriptional misregulation in cancer"
			},
			{
				"name":"05206 MicroRNAs in cancer"
			},
			{
				"name":"05205 Proteoglycans in cancer"
			},
			{
				"name":"05204 Chemical carcinogenesis - DNA adducts"
			},
			{
				"name":"05207 Chemical carcinogenesis - receptor activation"
			},
			{
				"name":"05208 Chemical carcinogenesis - reactive oxygen species"
			},
			{
				"name":"05203 Viral carcinogenesis"
			},
			{
				"name":"05230 Central carbon metabolism in cancer"
			},
			{
				"name":"05231 Choline metabolism in cancer"
			},
			{
				"name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer"
			}
			]
		},
		{
			"name":"09162 Cancer: specific types",
			"children":[
			{
				"name":"05210 Colorectal cancer"
			},
			{
				"name":"05212 Pancreatic cancer"
			},
			{
				"name":"05225 Hepatocellular carcinoma"
			},
			{
				"name":"05226 Gastric cancer"
			},
			{
				"name":"05214 Glioma"
			},
			{
				"name":"05216 Thyroid cancer"
			},
			{
				"name":"05221 Acute myeloid leukemia"
			},
			{
				"name":"05220 Chronic myeloid leukemia"
			},
			{
				"name":"05217 Basal cell carcinoma"
			},
			{
				"name":"05218 Melanoma"
			},
			{
				"name":"05211 Renal cell carcinoma"
			},
			{
				"name":"05219 Bladder cancer"
			},
			{
				"name":"05215 Prostate cancer"
			},
			{
				"name":"05213 Endometrial cancer"
			},
			{
				"name":"05224 Breast cancer"
			},
			{
				"name":"05222 Small cell lung cancer"
			},
			{
				"name":"05223 Non-small cell lung cancer"
			}
			]
		},
		{
			"name":"09172 Infectious disease: viral",
			"children":[
			{
				"name":"05166 Human T-cell leukemia virus 1 infection"
			},
			{
				"name":"05170 Human immunodeficiency virus 1 infection"
			},
			{
				"name":"05161 Hepatitis B"
			},
			{
				"name":"05160 Hepatitis C"
			},
			{
				"name":"05171 Coronavirus disease"
			},
			{
				"name":"05164 Influenza A"
			},
			{
				"name":"05162 Measles"
			},
			{
				"name":"05168 Herpes simplex virus 1 infection"
			},
			{
				"name":"05163 Human cytomegalovirus infection"
			},
			{
				"name":"05167 Kaposi sarcoma-associated herpesvirus infection"
			},
			{
				"name":"05169 Epstein-Barr virus infection"
			},
			{
				"name":"05165 Human papillomavirus infection"
			}
			]
		},
		{
			"name":"09171 Infectious disease: bacterial",
			"children":[
			{
				"name":"05110 Vibrio cholerae infection"
			},
			{
				"name":"05120 Epithelial cell signaling in Helicobacter pylori infection"
			},
			{
				"name":"05130 Pathogenic Escherichia coli infection"
			},
			{
				"name":"05132 Salmonella infection"
			},
			{
				"name":"05131 Shigellosis"
			},
			{
				"name":"05135 Yersinia infection"
			},
			{
				"name":"05133 Pertussis"
			},
			{
				"name":"05134 Legionellosis"
			},
			{
				"name":"05150 Staphylococcus aureus infection"
			},
			{
				"name":"05152 Tuberculosis"
			},
			{
				"name":"05100 Bacterial invasion of epithelial cells"
			}
			]
		},
		{
			"name":"09174 Infectious disease: parasitic",
			"children":[
			{
				"name":"05146 Amoebiasis"
			},
			{
				"name":"05144 Malaria"
			},
			{
				"name":"05145 Toxoplasmosis"
			},
			{
				"name":"05140 Leishmaniasis"
			},
			{
				"name":"05142 Chagas disease"
			},
			{
				"name":"05143 African trypanosomiasis"
			}
			]
		},
		{
			"name":"09163 Immune disease",
			"children":[
			{
				"name":"05310 Asthma"
			},
			{
				"name":"05322 Systemic lupus erythematosus"
			},
			{
				"name":"05323 Rheumatoid arthritis"
			},
			{
				"name":"05320 Autoimmune thyroid disease"
			},
			{
				"name":"05321 Inflammatory bowel disease"
			},
			{
				"name":"05330 Allograft rejection"
			},
			{
				"name":"05332 Graft-versus-host disease"
			},
			{
				"name":"05340 Primary immunodeficiency"
			}
			]
		},
		{
			"name":"09164 Neurodegenerative disease",
			"children":[
			{
				"name":"05010 Alzheimer disease"
			},
			{
				"name":"05012 Parkinson disease"
			},
			{
				"name":"05014 Amyotrophic lateral sclerosis"
			},
			{
				"name":"05016 Huntington disease"
			},
			{
				"name":"05017 Spinocerebellar ataxia"
			},
			{
				"name":"05020 Prion disease"
			},
			{
				"name":"05022 Pathways of neurodegeneration - multiple diseases"
			}
			]
		},
		{
			"name":"09165 Substance dependence",
			"children":[
			{
				"name":"05030 Cocaine addiction"
			},
			{
				"name":"05031 Amphetamine addiction"
			},
			{
				"name":"05032 Morphine addiction"
			},
			{
				"name":"05033 Nicotine addiction"
			},
			{
				"name":"05034 Alcoholism"
			}
			]
		},
		{
			"name":"09166 Cardiovascular disease",
			"children":[
			{
				"name":"05417 Lipid and atherosclerosis"
			},
			{
				"name":"05418 Fluid shear stress and atherosclerosis"
			},
			{
				"name":"05410 Hypertrophic cardiomyopathy"
			},
			{
				"name":"05412 Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"05414 Dilated cardiomyopathy"
			},
			{
				"name":"05415 Diabetic cardiomyopathy"
			},
			{
				"name":"05416 Viral myocarditis"
			}
			]
		},
		{
			"name":"09167 Endocrine and metabolic disease",
			"children":[
			{
				"name":"04930 Type II diabetes mellitus"
			},
			{
				"name":"04940 Type I diabetes mellitus"
			},
			{
				"name":"04950 Maturity onset diabetes of the young"
			},
			{
				"name":"04936 Alcoholic liver disease"
			},
			{
				"name":"04932 Non-alcoholic fatty liver disease"
			},
			{
				"name":"04931 Insulin resistance"
			},
			{
				"name":"04933 AGE-RAGE signaling pathway in diabetic complications"
			},
			{
				"name":"04934 Cushing syndrome"
			}
			]
		},
		{
			"name":"09175 Drug resistance: antimicrobial",
			"children":[
			{
				"name":"01501 beta-Lactam resistance [PATH:shg01501]",
				"children":[
				{
					"name":"Sph21_0789 Beta-N-acetylhexosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0790 Beta-N-acetylhexosaminidase\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1235 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_1402 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_3629 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_1236 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_1401 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_3628 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_0028 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0421 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1124 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1486 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1696 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2597 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2828 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3603 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3635 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4059 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4634 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4898 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0029 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0422 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1123 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1487 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1695 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2598 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2827 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3602 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3636 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4058 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4633 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4897 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0423 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1488 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2599 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2826 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4896 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3115 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_5240 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_2376 penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_0061 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_3243 Beta-lactamase\tK17837 bla2; metallo-beta-lactamase class B [EC:3.5.2.6]"
				},
				{
					"name":"Sph21_2800 Beta-lactamase\tK17838 oxa; beta-lactamase class D [EC:3.5.2.6]"
				}
				]
			},
			{
				"name":"01502 Vancomycin resistance [PATH:shg01502]",
				"children":[
				{
					"name":"Sph21_3074 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Sph21_4678 Alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"Sph21_1352 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate\/D-alanyl-D-alanyl ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"Sph21_0059 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Sph21_0056 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				}
				]
			},
			{
				"name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:shg01503]",
				"children":[
				{
					"name":"Sph21_2535 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_2536 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_1406 protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_3618 peptidase S1 and S6 chymotrypsin\/Hap\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_0028 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0421 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1124 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1486 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1696 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2597 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2828 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3603 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3635 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4059 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4634 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4898 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0029 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0422 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1123 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1487 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1695 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2598 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2827 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3602 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3636 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4058 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4633 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4897 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1542 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"Sph21_4054 Lysylphosphatidylglycerol synthetase\/UPF0104\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				}
				]
			}
			]
		},
		{
			"name":"09176 Drug resistance: antineoplastic",
			"children":[
			{
				"name":"01521 EGFR tyrosine kinase inhibitor resistance"
			},
			{
				"name":"01524 Platinum drug resistance"
			},
			{
				"name":"01523 Antifolate resistance"
			},
			{
				"name":"01522 Endocrine resistance"
			}
			]
		}
		]
	},
	{
		"name":"09180 Brite Hierarchies",
		"children":[
		{
			"name":"09181 Protein families: metabolism",
			"children":[
			{
				"name":"01000 Enzymes [BR:shg01000]"
			},
			{
				"name":"01001 Protein kinases [BR:shg01001]",
				"children":[
				{
					"name":"Sph21_3073 PASTA domain containing protein\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"Sph21_4943 serine\/threonine protein kinase\tK08884 K08884; serine\/threonine protein kinase, bacterial [EC:2.7.11.1]"
				},
				{
					"name":"Sph21_1810 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_1959 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_2026 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_1333 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1369 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4070 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4258 Osmosensitive K channel His kinase sensor\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4504 response regulator receiver sensor signal transduction histidine kinase\tK07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2076 integral membrane sensor signal transduction histidine kinase\tK07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_0874 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2387 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_3408 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4640 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4259 multi-sensor signal transduction histidine kinase\tK11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2045 multi-sensor signal transduction multi-kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2157 putative PAS\/PAC sensor protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2355 Diverse 7TM receptor transmembrane region\tK20971 ladS; two-component system, sensor histidine kinase LadS"
				},
				{
					"name":"Sph21_1112 response regulator receiver sensor signal transduction histidine kinase\tK11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"01009 Protein phosphatases and associated proteins [BR:shg01009]",
				"children":[
				{
					"name":"Sph21_1238 Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_0860 hypothetical protein\tK20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"01002 Peptidases and inhibitors [BR:shg01002]",
				"children":[
				{
					"name":"Sph21_0043 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"Sph21_2364 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"Sph21_5158 peptidase C1A papain\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"Sph21_2239 GMP synthase (glutamine-hydrolyzing)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"Sph21_0664 peptidase C26\tK07010 K07010; putative glutamine amidotransferase"
				},
				{
					"name":"Sph21_0591 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1895 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_4095 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1148 NLP\/P60 protein\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
				},
				{
					"name":"Sph21_3003 NLP\/P60 protein\tK20742 ykfC; gamma-D-glutamyl-L-lysine dipeptidyl-peptidase [EC:3.4.14.13]"
				},
				{
					"name":"Sph21_3889 NLP\/P60 protein\tK20742 ykfC; gamma-D-glutamyl-L-lysine dipeptidyl-peptidase [EC:3.4.14.13]"
				},
				{
					"name":"Sph21_2214 Amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"Sph21_3183 Glutamate synthase (ferredoxin)\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"Sph21_2063 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"Sph21_3307 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"Sph21_0357 intracellular protease, PfpI family\tK05520 yhbO; deglycase [EC:3.5.1.124]"
				},
				{
					"name":"Sph21_0360 ErfK\/YbiS\/YcfS\/YnhG family protein\tK21470 ldtD; L,D-transpeptidase"
				},
				{
					"name":"Sph21_0760 ErfK\/YbiS\/YcfS\/YnhG family protein\tK21470 ldtD; L,D-transpeptidase"
				},
				{
					"name":"Sph21_1304 Abortive infection protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"Sph21_4226 Abortive infection protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"Sph21_4440 hypothetical protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"Sph21_4824 Abortive infection protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"Sph21_1641 Membrane alanyl aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]"
				},
				{
					"name":"Sph21_4033 Oligopeptidase A\tK01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]"
				},
				{
					"name":"Sph21_5215 oligoendopeptidase, M3 family\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_4637 Endothelin-converting enzyme 1\tK07386 pepO; putative endopeptidase [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_0519 peptidase M16 domain protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_3675 peptidase M16 domain protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_3676 peptidase M16 domain protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_1081 Membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Sph21_2875 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Sph21_1379 peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
				},
				{
					"name":"Sph21_5015 peptidase dimerization domain protein\tK12941 abgB; aminobenzoyl-glutamate utilization protein B"
				},
				{
					"name":"Sph21_1736 methionine aminopeptidase, type I\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"Sph21_4274 methionine aminopeptidase, type I\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"Sph21_4613 methionine aminopeptidase, type I\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"Sph21_0992 peptidase M24\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
				},
				{
					"name":"Sph21_3545 peptidase M24\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
				},
				{
					"name":"Sph21_2671 Glutamate carboxypeptidase II\tK01301 NAALAD; N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21]"
				},
				{
					"name":"Sph21_1057 ATP-dependent metalloprotease FtsH\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_0775 peptidase M48 Ste24p\tK07387 K07387; metalloprotease [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_5218 Dipeptidyl-peptidase III\tK01277 DPP3; dipeptidyl-peptidase III [EC:3.4.14.4]"
				},
				{
					"name":"Sph21_2920 membrane-associated zinc metalloprotease\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_1235 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_1402 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_3629 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_3673 protein of unknown function DUF980\tK09933 mtfA; MtfA peptidase"
				},
				{
					"name":"Sph21_1406 protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_3618 peptidase S1 and S6 chymotrypsin\/Hap\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_0572 peptidase S8 and S53 subtilisin kexin sedolisin\tK13274 wprA; cell wall-associated protease [EC:3.4.21.-]"
				},
				{
					"name":"Sph21_1453 Prolyl oligopeptidase\tK01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]"
				},
				{
					"name":"Sph21_0993 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_2473 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_1246 Oligopeptidase B\tK01354 ptrB; oligopeptidase B [EC:3.4.21.83]"
				},
				{
					"name":"Sph21_1073 D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"Sph21_2814 ATP-dependent Clp protease proteolytic subunit\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"Sph21_2925 ATP-dependent Clp protease proteolytic subunit\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"Sph21_2984 anti-sigma H sporulation factor, LonB\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]"
				},
				{
					"name":"Sph21_0424 signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"Sph21_4185 alpha\/beta hydrolase fold protein\tK01259 pip; proline iminopeptidase [EC:3.4.11.5]"
				},
				{
					"name":"Sph21_0376 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"Sph21_1361 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"Sph21_1397 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"Sph21_1002 peptidase S41\tK08676 tri; tricorn protease [EC:3.4.21.-]"
				},
				{
					"name":"Sph21_3616 peptidase S41\tK08676 tri; tricorn protease [EC:3.4.21.-]"
				},
				{
					"name":"Sph21_3904 peptidase S45 penicillin amidase\tK01434 pac; penicillin G amidase [EC:3.5.1.11]"
				},
				{
					"name":"Sph21_4022 signal peptide peptidase SppA, 67K type\tK04773 sppA; protease IV [EC:3.4.21.-]"
				},
				{
					"name":"Sph21_1474 Peptidase S54, rhomboid domain\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
				},
				{
					"name":"Sph21_1475 Peptidase S54, rhomboid domain\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
				},
				{
					"name":"Sph21_3230 Peptidase S54, rhomboid domain\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
				},
				{
					"name":"Sph21_1426 peptidase U61 LD-carboxypeptidase A\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"Sph21_3887 peptidase U61 LD-carboxypeptidase A\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"Sph21_0527 Beta-aspartyl-peptidase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"Sph21_3879 gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_5118 Gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"Sph21_4125 alpha-2-macroglobulin domain protein\tK06894 yfhM; alpha-2-macroglobulin"
				}
				]
			},
			{
				"name":"01003 Glycosyltransferases [BR:shg01003]",
				"children":[
				{
					"name":"Sph21_2471 Dolichyl-phosphate beta-D-mannosyltransferase\tK00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]"
				},
				{
					"name":"Sph21_1635 Starch synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Sph21_5138 Glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"Sph21_2295 Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_4124 penicillin-binding protein 1C\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_3115 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_5240 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_0057 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_2375 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1799 glycosyl transferase group 1\tK13658 gumI; beta-1,4-mannosyltransferase [EC:2.4.1.251]"
				},
				{
					"name":"Sph21_2071 glycosyl transferase group 1\tK13658 gumI; beta-1,4-mannosyltransferase [EC:2.4.1.251]"
				},
				{
					"name":"Sph21_1323 trehalose-phosphatase\tK16055 TPS; trehalose 6-phosphate synthase\/phosphatase [EC:2.4.1.15 3.1.3.12]"
				}
				]
			},
			{
				"name":"01005 Lipopolysaccharide biosynthesis proteins [BR:shg01005]",
				"children":[
				{
					"name":"Sph21_1542 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"Sph21_5175 lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]"
				},
				{
					"name":"Sph21_1541 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"Sph21_1540 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]"
				},
				{
					"name":"Sph21_1451 metallophosphoesterase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]"
				},
				{
					"name":"Sph21_0350 Tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]"
				},
				{
					"name":"Sph21_1257 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_3162 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_4379 lipid A biosynthesis acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"Sph21_4142 Protein of unknown function DUF2219\tK09953 lpxR; lipid A 3-O-deacylase [EC:3.1.1.-]"
				},
				{
					"name":"Sph21_1048 Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]"
				},
				{
					"name":"Sph21_3365 2-dehydro-3-deoxyphosphooctonate aldolase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]"
				},
				{
					"name":"Sph21_3514 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]"
				},
				{
					"name":"Sph21_3140 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]"
				},
				{
					"name":"Sph21_3363 KpsF\/GutQ family protein\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]"
				},
				{
					"name":"Sph21_3830 hydrolase, HAD-superfamily, subfamily IIIA\tK03273 gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]"
				},
				{
					"name":"Sph21_3829 cytidyltransferase-related domain protein\tK03272 gmhC; D-beta-D-heptose 7-phosphate kinase \/ D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]"
				},
				{
					"name":"Sph21_1781 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"Sph21_1832 glycosyl transferase family 4\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:shg01011]",
				"children":[
				{
					"name":"Sph21_2929 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"Sph21_1700 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"Sph21_0055 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"Sph21_0058 UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"Sph21_0060 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"Sph21_4678 Alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"Sph21_3074 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"Sph21_3157 Glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"Sph21_1426 peptidase U61 LD-carboxypeptidase A\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"Sph21_3887 peptidase U61 LD-carboxypeptidase A\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"Sph21_0059 Phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"Sph21_0056 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"Sph21_0549 Undecaprenyl-diphosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_2431 phosphoesterase PA-phosphatase related protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"Sph21_3115 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_5240 Peptidoglycan glycosyltransferase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"Sph21_4124 penicillin-binding protein 1C\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_2376 penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_0061 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_1073 D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"Sph21_2295 Monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_0057 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_2375 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_0360 ErfK\/YbiS\/YcfS\/YnhG family protein\tK21470 ldtD; L,D-transpeptidase"
				},
				{
					"name":"Sph21_0760 ErfK\/YbiS\/YcfS\/YnhG family protein\tK21470 ldtD; L,D-transpeptidase"
				},
				{
					"name":"Sph21_1148 NLP\/P60 protein\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
				},
				{
					"name":"Sph21_1146 Lytic transglycosylase catalytic\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
				},
				{
					"name":"Sph21_5271 Lytic transglycosylase catalytic\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
				},
				{
					"name":"Sph21_3072 aminodeoxychorismate lyase\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
				},
				{
					"name":"Sph21_2421 rare lipoprotein A\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
				},
				{
					"name":"Sph21_2535 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_2536 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_0771 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				}
				]
			},
			{
				"name":"01004 Lipid biosynthesis proteins [BR:shg01004]",
				"children":[
				{
					"name":"Sph21_1317 malonyl CoA-acyl carrier protein transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"Sph21_0011 3-oxoacyl-(acyl-carrier-protein) synthase 3\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_2077 Beta-ketoacyl-acyl-carrier-protein synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_2124 Beta-ketoacyl-acyl-carrier-protein synthase I\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"Sph21_1357 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_4075 3-oxoacyl-(acyl-carrier-protein) synthase 2\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"Sph21_0337 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2365 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_2703 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_4360 3-oxoacyl-(acyl-carrier-protein) reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"Sph21_1541 UDP-3-O-(3-hydroxymyristoyl) N-acetylglucosamine deacetylase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"Sph21_0398 Enoyl-(acyl-carrier-protein) reductase (NADH)\tK00208 fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]"
				},
				{
					"name":"Sph21_3075 acyl-ACP thioesterase\tK12500 tesC; thioesterase III [EC:3.1.2.-]"
				},
				{
					"name":"Sph21_4485 fatty acid desaturase\tK00507 SCD; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]"
				},
				{
					"name":"Sph21_4113 Acyl-(acyl-carrier-protein) desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				},
				{
					"name":"Sph21_3689 fatty acid desaturase\tK04712 DEGS; sphingolipid 4-desaturase\/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]"
				},
				{
					"name":"Sph21_5179 acetate\/CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_0010 Phosphate acyltransferase\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"Sph21_2990 Glycerol-3-phosphate acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"Sph21_1576 phospholipid\/glycerol acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				}
				]
			},
			{
				"name":"01008 Polyketide biosynthesis proteins"
			},
			{
				"name":"01006 Prenyltransferases [BR:shg01006]",
				"children":[
				{
					"name":"Sph21_3092 Geranyltranstransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"Sph21_1116 Trans-hexaprenyltranstransferase\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]"
				},
				{
					"name":"Sph21_5202 Undecaprenyl pyrophosphate synthase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"Sph21_1617 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"Sph21_2423 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"Sph21_5212 4-hydroxybenzoate polyprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]"
				},
				{
					"name":"Sph21_1557 Protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				}
				]
			},
			{
				"name":"01007 Amino acid related enzymes [BR:shg01007]",
				"children":[
				{
					"name":"Sph21_1436 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Sph21_0772 Glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Sph21_3907 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Sph21_3512 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"Sph21_1472 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Sph21_3007 Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Sph21_1427 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Sph21_0041 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Sph21_2462 Valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Sph21_0546 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Sph21_2410 Lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"Sph21_1132 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Sph21_3337 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Sph21_1306 Histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Sph21_1705 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Sph21_5220 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Sph21_4651 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Sph21_2963 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Sph21_3106 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Sph21_1460 Phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3955 Phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3216 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3987 Aspartate transaminase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"Sph21_3277 Kynurenine--oxoglutarate transaminase\tK14287 ybdL; methionine transaminase [EC:2.6.1.88]"
				},
				{
					"name":"Sph21_1606 LL-diaminopimelate aminotransferase\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"Sph21_5144 Histidinol-phosphate aminotransferase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"Sph21_0050 Glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Sph21_1459 2-amino-3-ketobutyrate coenzyme A ligase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"Sph21_3313 8-amino-7-oxononanoate synthase\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"Sph21_3026 Glycine C-acetyltransferase\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"Sph21_3678 L-lysine 6-transaminase\tK03918 lat; L-lysine 6-transaminase [EC:2.6.1.36]"
				},
				{
					"name":"Sph21_1037 Acetylornithine transaminase\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"Sph21_3316 adenosylmethionine-8-amino-7-oxononanoate aminotransferase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]"
				},
				{
					"name":"Sph21_5195 Glutamate-1-semialdehyde 2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]"
				},
				{
					"name":"Sph21_0743 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3549 Aminodeoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"Sph21_3090 Phosphoserine aminotransferase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00199 Cytochrome P450"
			},
			{
				"name":"00194 Photosynthesis proteins [BR:shg00194]",
				"children":[
				{
					"name":"Sph21_2291 ATPase, F1 complex, delta\/epsilon subunit\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"Sph21_2292 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"Sph21_5231 ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"Sph21_5232 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"Sph21_5233 ATP synthase subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"Sph21_5234 ATP synthase subunit b\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"Sph21_5235 ATP synthase subunit c\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"Sph21_5236 ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				}
				]
			}
			]
		},
		{
			"name":"09182 Protein families: genetic information processing",
			"children":[
			{
				"name":"03000 Transcription factors [BR:shg03000]",
				"children":[
				{
					"name":"Sph21_0901 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_3497 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_4390 transcriptional regulator, AraC family\tK02508 hpaA; AraC family transcriptional regulator, 4-hydroxyphenylacetate 3-monooxygenase operon regulatory protein"
				},
				{
					"name":"Sph21_0822 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_1416 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_1926 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_1985 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_2271 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_2503 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_2672 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_2678 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_3024 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_3597 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4204 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4342 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4449 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4517 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4988 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_5006 transcriptional regulator, AraC family\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"Sph21_4443 transcriptional regulator, AraC family\tK20968 exsA; AraC family transcriptional regulator, exoenzyme S synthesis regulatory protein ExsA"
				},
				{
					"name":"Sph21_4867 transcriptional regulator, AraC family\tK20968 exsA; AraC family transcriptional regulator, exoenzyme S synthesis regulatory protein ExsA"
				},
				{
					"name":"Sph21_4997 Helix-turn-helix, AraC domain\tK20968 exsA; AraC family transcriptional regulator, exoenzyme S synthesis regulatory protein ExsA"
				},
				{
					"name":"Sph21_2783 transcriptional regulator, AraC family\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Sph21_4272 methylated-DNA\/protein-cysteine methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Sph21_1915 transcriptional regulator, LysR family\tK03576 metR; LysR family transcriptional regulator, regulator for metE and metH"
				},
				{
					"name":"Sph21_1534 transcriptional regulator, LysR family\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"Sph21_1063 transcriptional regulator, LysR family\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				},
				{
					"name":"Sph21_4074 transcriptional regulator, LysR family\tK21900 cysL; LysR family transcriptional regulator, transcriptional activator of the cysJI operon"
				},
				{
					"name":"Sph21_0430 transcriptional regulator, DeoR family\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"Sph21_2910 transcriptional regulator, DeoR family\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"Sph21_3847 transcriptional regulator, DeoR family\tK22103 glcR; DeoR family transcriptional regulator, carbon catabolite repression regulator"
				},
				{
					"name":"Sph21_0199 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_0370 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_0574 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_0605 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_0731 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_1909 periplasmic binding protein\/LacI transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_2839 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_2879 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_3899 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_3966 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_4799 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_5120 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Sph21_4247 transcriptional regulator, GntR family with UTRA sensor domain\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Sph21_0539 transcriptional regulator, GntR family with aminotransferase domain\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"Sph21_3311 transcriptional regulator, GntR family with aminotransferase domain\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"Sph21_1308 transcriptional regulator, AsnC family\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"Sph21_0528 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_2789 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_4012 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_2994 ferric uptake regulator, Fur family\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"Sph21_3094 ferric uptake regulator, Fur family\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"Sph21_4616 ferric-uptake regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"Sph21_4914 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Sph21_3585 transcriptional regulator, Crp\/Fnr family\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"Sph21_0218 regulatory protein ArsR\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"Sph21_1350 transcriptional regulator, PadR-like family\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"Sph21_0318 iron (metal) dependent repressor, DtxR family\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"Sph21_1236 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_1401 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_3628 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_1059 biotin\/acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Sph21_0442 transcriptional regulator, XRE family\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"Sph21_3773 hypothetical protein\tK22301 opcR; HTH-type transcriptional regulator, osmoprotectant uptake regulator"
				},
				{
					"name":"Sph21_4881 sigma54 specific transcriptional regulator, Fis family\tK15836 fhlA; formate hydrogenlyase transcriptional activator"
				},
				{
					"name":"Sph21_4885 sigma54 specific transcriptional regulator, Fis family\tK15836 fhlA; formate hydrogenlyase transcriptional activator"
				},
				{
					"name":"Sph21_4888 sigma54 specific transcriptional regulator, Fis family\tK15836 fhlA; formate hydrogenlyase transcriptional activator"
				},
				{
					"name":"Sph21_0427 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Sph21_5167 GreA\/GreB family elongation factor\tK06140 rnk; regulator of nucleoside diphosphate kinase"
				},
				{
					"name":"Sph21_1147 phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Sph21_2231 Uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Sph21_5105 FMN-binding negative transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"Sph21_3343 protein of unknown function DUF179\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"Sph21_0042 DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Sph21_0064 Protein mraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			},
			{
				"name":"03021 Transcription machinery [BR:shg03021]",
				"children":[
				{
					"name":"Sph21_1742 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_2406 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_2407 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_3256 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Sph21_4481 RNA polymerase, sigma 70 subunit, RpoD subfamily\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"Sph21_2131 RNA polymerase, sigma-24 subunit, ECF subfamily\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"Sph21_3917 RNA polymerase, sigma-24 subunit, ECF subfamily\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0462 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0486 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0805 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0806 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0843 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0972 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1281 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1664 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1778 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1869 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1877 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1890 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1918 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_1965 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2264 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2492 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2497 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2764 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2833 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2938 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_2954 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_3403 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4232 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4293 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4311 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4413 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4695 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4805 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_4857 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_5020 RNA polymerase, sigma-24 subunit, ECF subfamily\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"Sph21_0330 RNA polymerase, sigma 54 subunit, RpoN\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"Sph21_1609 NusA antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"Sph21_4007 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"Sph21_2401 NusG antitermination factor\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"Sph21_2532 anti-anti-sigma factor\tK04749 rsbV; anti-sigma B factor antagonist"
				},
				{
					"name":"Sph21_0042 DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Sph21_1571 transcription elongation factor GreA\tK03624 greA; transcription elongation factor GreA"
				},
				{
					"name":"Sph21_4019 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				}
				]
			},
			{
				"name":"03019 Messenger RNA biogenesis [BR:shg03019]",
				"children":[
				{
					"name":"Sph21_1127 ribonuclease, Rne\/Rng family\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
				},
				{
					"name":"Sph21_1358 Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Sph21_3952 2,3 cyclic-nucleotide 2-phosphodiesterase\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_3093 ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"Sph21_0774 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3518 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3885 DEAD\/DEAH box helicase domain protein\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_3878 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_2937 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3364 ATP-dependent DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Sph21_3088 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"Sph21_4019 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"Sph21_1062 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_3894 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Sph21_0532 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_3169 polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"Sph21_2713 polyphosphate kinase 2\tK22468 ppk2; polyphosphate kinase [EC:2.7.4.34]"
				},
				{
					"name":"Sph21_1998 ATP-dependent helicase HrpB\tK03579 hrpB; ATP-dependent RNA helicase HrpB [EC:5.6.2.6]"
				}
				]
			},
			{
				"name":"03041 Spliceosome"
			},
			{
				"name":"03011 Ribosome [BR:shg03011]",
				"children":[
				{
					"name":"Sph21_3134 RNA binding S1 domain protein\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"Sph21_1445 ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"Sph21_1720 ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"Sph21_1741 ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"Sph21_1732 ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"Sph21_2352 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"Sph21_3980 ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"Sph21_1729 ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"Sph21_1446 ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"Sph21_3978 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"Sph21_1740 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"Sph21_3981 ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"Sph21_1739 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"Sph21_1728 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"Sph21_3076 ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"Sph21_1325 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"Sph21_1724 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"Sph21_2351 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"Sph21_1718 ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"Sph21_3959 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"Sph21_2394 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"Sph21_2458 hypothetical protein\tK19033 PSRP4; 30S ribosomal protein S31\/Thx"
				},
				{
					"name":"Sph21_2403 ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"Sph21_1717 ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"Sph21_1714 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"Sph21_1715 ribosomal protein L4\/L1e\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"Sph21_1727 ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"Sph21_1730 ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"Sph21_2350 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"Sph21_2404 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"Sph21_2402 ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"Sph21_2405 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"Sph21_1447 ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"Sph21_1725 ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"Sph21_1734 ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"Sph21_1721 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"Sph21_1743 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"Sph21_1731 ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"Sph21_1328 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"Sph21_2966 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"Sph21_3305 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"Sph21_1719 ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"Sph21_1716 Ribosomal protein L25\/L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"Sph21_1726 ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"Sph21_3306 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"Sph21_5182 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"Sph21_1723 ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"Sph21_1733 ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"Sph21_3043 50S ribosomal protein L31 type B\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"Sph21_0009 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"Sph21_5183 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"Sph21_0328 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"Sph21_2965 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"Sph21_1738 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36"
				},
				{
					"name":"Sph21_5155 50S ribosomal protein L25\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"Sph21_R0009 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0034 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0068 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0007 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0013 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0037 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0065 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0038 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0064 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				}
				]
			},
			{
				"name":"03009 Ribosome biogenesis [BR:shg03009]",
				"children":[
				{
					"name":"Sph21_1358 Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Sph21_0363 GTP-binding protein Era-like-protein\tK03595 era; GTPase"
				},
				{
					"name":"Sph21_0075 GTPase obg\tK03979 obgE; GTPase [EC:3.6.5.-]"
				},
				{
					"name":"Sph21_0042 DnaK suppressor protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"Sph21_1609 NusA antitermination factor\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"Sph21_4007 NusB antitermination factor\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"Sph21_2401 NusG antitermination factor\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"Sph21_0006 Ribosomal RNA small subunit methyltransferase A\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"Sph21_3154 Conserved hypothetical protein CHP00095\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"Sph21_1604 Ribosomal RNA small subunit methyltransferase E\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"Sph21_2523 Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Sph21_0063 Ribosomal RNA small subunit methyltransferase H\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"Sph21_1497 Uroporphyrin-III C\/tetrapyrrole (Corrin\/Porphyrin) methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Sph21_5221 Ribosomal RNA small subunit methyltransferase I\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"Sph21_3057 RNA methyltransferase, TrmH family, group 3\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"Sph21_0344 Ribosomal RNA large subunit methyltransferase H\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"Sph21_1086 PUA domain containing protein\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Sph21_1666 SAM dependent methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"Sph21_1331 rRNA (guanine-N(2)-)-methyltransferase\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"Sph21_1138 Ribosomal RNA large subunit methyltransferase N\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"Sph21_1250 RNA methyltransferase, TrmA family\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"Sph21_5272 pseudouridine synthase Rsu\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"Sph21_3110 pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"Sph21_1986 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Sph21_2297 pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Sph21_3550 pseudouridine synthase, RluA family\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"Sph21_3982 alpha-L-glutamate ligase, RimK family\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
				},
				{
					"name":"Sph21_1326 Ribosome maturation factor rimM\tK02860 rimM; 16S rRNA processing protein RimM"
				},
				{
					"name":"Sph21_5186 Ribosomal protein S12 methylthiotransferase rimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
				},
				{
					"name":"Sph21_3046 Ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"Sph21_1127 ribonuclease, Rne\/Rng family\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
				},
				{
					"name":"Sph21_0764 Holliday junction resolvase\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_3878 DEAD\/DEAH box helicase domain protein\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"Sph21_1435 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Sph21_3205 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"Sph21_0369 GTP-binding protein engA\tK03977 engA; GTPase"
				},
				{
					"name":"Sph21_1159 GTP-binding proten HflX\tK03665 hflX; GTPase"
				},
				{
					"name":"Sph21_2426 Sua5\/YciO\/YrdC\/YwlC family protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"Sph21_2995 (p)ppGpp synthetase I, SpoT\/RelA\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"Sph21_1160 Ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
				},
				{
					"name":"Sph21_1610 Ribosome maturation factor rimP\tK09748 rimP; ribosome maturation factor RimP"
				},
				{
					"name":"Sph21_2275 RNA-binding S4 domain protein\tK14761 rlbA; ribosome-associated protein"
				},
				{
					"name":"Sph21_1058 iojap-like protein\tK09710 ybeB; ribosome-associated protein"
				},
				{
					"name":"Sph21_1292 metalloprotease ybeY\tK07042 ybeY; probable rRNA maturation factor"
				},
				{
					"name":"Sph21_2398 ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
				},
				{
					"name":"Sph21_3129 GTP-binding protein YchF\tK06942 ychF; ribosome-binding ATPase"
				},
				{
					"name":"Sph21_0008 protein of unknown function DUF177\tK07040 yceD; DUF177 domain-containing protein"
				}
				]
			},
			{
				"name":"03016 Transfer RNA biogenesis [BR:shg03016]",
				"children":[
				{
					"name":"Sph21_2533 Ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"Sph21_2425 polynucleotide adenylyltransferase\/metal dependent phosphohydrolase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				},
				{
					"name":"Sph21_5037 protein of unknown function UPF0027\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"Sph21_1436 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Sph21_4651 Prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"Sph21_0041 Isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"Sph21_0546 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Sph21_1427 Methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"Sph21_0772 Glutaminyl-tRNA synthetase\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"Sph21_3007 Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Sph21_2410 Lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"Sph21_1132 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Sph21_3106 alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"Sph21_3337 Asparaginyl-tRNA synthetase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"Sph21_1705 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Sph21_2963 threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"Sph21_5220 seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"Sph21_1472 cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"Sph21_2462 Valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"Sph21_1306 Histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"Sph21_1460 Phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3955 Phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"Sph21_3907 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Sph21_3512 tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"Sph21_1380 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"Sph21_1572 histidine triad (HIT) protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"Sph21_0747 (Dimethylallyl)adenosine tRNA methylthiotransferase miaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"Sph21_3053 MiaB-like tRNA modifying enzyme\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				},
				{
					"name":"Sph21_1084 tRNA (guanine-N(7)-)-methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"Sph21_2416 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"Sph21_0550 tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"Sph21_3019 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3741 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3997 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_2426 Sua5\/YciO\/YrdC\/YwlC family protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"Sph21_1617 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"Sph21_2423 tRNA dimethylallyltransferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"Sph21_4135 tRNA modification GTPase mnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"Sph21_1300 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"Sph21_0327 Ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"Sph21_R0048 rnpB; RNA component of RNaseP\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"Sph21_0410 ATP-binding cassette protein, ChvD family\tK06020 ettA; energy-dependent translational throttle protein EttA"
				},
				{
					"name":"Sph21_1067 CMP\/dCMP deaminase zinc-binding protein\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				},
				{
					"name":"Sph21_1303 TIM-barrel protein, nifR3 family\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				},
				{
					"name":"Sph21_2217 Methyltransferase type 12\tK15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"Sph21_2817 Methyltransferase type 11\tK15256 cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"Sph21_1327 tRNA (guanine-N(1)-)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"Sph21_3639 methyltransferase small\tK15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]"
				},
				{
					"name":"Sph21_3187 tRNA\/rRNA methyltransferase (SpoU)\tK03437 spoU; RNA methyltransferase, TrmH family"
				},
				{
					"name":"Sph21_3175 tRNA-specific 2-thiouridylase mnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"Sph21_0004 iron-sulfur cluster assembly accessory protein\tK13628 iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"Sph21_3018 iron-sulfur cluster assembly accessory protein\tK13628 iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"Sph21_4132 tRNA-hydroxylase\tK06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]"
				},
				{
					"name":"Sph21_3991 S-adenosylmethionine:tRNA ribosyltransferase-isomerase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"Sph21_1319 6-pyruvoyl tetrahydropterin synthase and hypothetical protein\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"Sph21_3290 Radical SAM domain protein\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"Sph21_3535 iron-sulfur cluster binding protein\tK18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"Sph21_2521 Queuine tRNA-ribosyltransferase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"Sph21_1620 tRNA(Ile)-lysidine synthase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"Sph21_0325 universal protein YeaZ\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"Sph21_0567 O-sialoglycoprotein endopeptidase\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"Sph21_1537 Uncharacterized protein family UPF0079, ATPase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"Sph21_3659 UBA\/THIF-type NAD\/FAD binding protein\tK22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase"
				},
				{
					"name":"Sph21_3093 ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"Sph21_3088 Polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"Sph21_4405 PilT protein domain protein\tK18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]"
				}
				]
			},
			{
				"name":"03012 Translation factors [BR:shg03012]",
				"children":[
				{
					"name":"Sph21_1579 translation initiation factor SUI1\tK03113 EIF1; translation initiation factor 1"
				},
				{
					"name":"Sph21_1608 translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"Sph21_2964 Translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"Sph21_3537 ABC transporter related protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"Sph21_1444 Elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"Sph21_2399 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Sph21_3979 translation elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Sph21_1449 Peptide chain release factor 1\tK02835 prfA; peptide chain release factor 1"
				},
				{
					"name":"Sph21_1431 Ribosome-recycling factor\tK02838 frr; ribosome recycling factor"
				},
				{
					"name":"Sph21_3389 protein-(glutamine-N5) methyltransferase, release factor-specific\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]"
				},
				{
					"name":"Sph21_5154 Peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
				},
				{
					"name":"Sph21_1737 Translation initiation factor IF-1\tK02518 infA; translation initiation factor IF-1"
				},
				{
					"name":"Sph21_1544 Elongation factor P\tK02356 efp; elongation factor P"
				},
				{
					"name":"Sph21_0678 hypothetical protein\tK02836 prfB; peptide chain release factor 2"
				},
				{
					"name":"Sph21_3645 peptide chain release factor 3\tK02837 prfC; peptide chain release factor 3"
				},
				{
					"name":"Sph21_3136 Class I peptide chain release factor\tK15034 yaeJ; ribosome-associated protein"
				}
				]
			},
			{
				"name":"03110 Chaperones and folding catalysts [BR:shg03110]",
				"children":[
				{
					"name":"Sph21_3149 ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
				},
				{
					"name":"Sph21_0409 ATPase AAA-2 domain protein\tK03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC"
				},
				{
					"name":"Sph21_2926 Sigma 54 interacting domain protein\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
				},
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Sph21_3120 Chaperone protein dnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"Sph21_0783 chaperone DnaJ domain protein\tK05516 cbpA; curved DNA-binding protein"
				},
				{
					"name":"Sph21_3121 Protein grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"Sph21_0002 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Sph21_2858 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Sph21_3240 heat shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"Sph21_2432 RNA-binding S4 domain protein\tK04762 hslR; ribosome-associated heat shock protein Hsp15"
				},
				{
					"name":"Sph21_0752 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Sph21_4573 Chaperonin Cpn10\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Sph21_1406 protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_3618 peptidase S1 and S6 chymotrypsin\/Hap\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"Sph21_1057 ATP-dependent metalloprotease FtsH\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
				},
				{
					"name":"Sph21_5236 ATP synthase subunit a\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"Sph21_2742 hypothetical protein\tK06006 cpxP; periplasmic protein CpxP\/Spy"
				},
				{
					"name":"Sph21_0572 peptidase S8 and S53 subtilisin kexin sedolisin\tK13274 wprA; cell wall-associated protease [EC:3.4.21.-]"
				},
				{
					"name":"Sph21_0646 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0655 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0656 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_1083 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_3771 Beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"Sph21_0347 peptidyl-prolyl cis-trans isomerase cyclophilin type\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_1410 PpiC-type peptidyl-prolyl cis-trans isomerase\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_1243 peptidylprolyl isomerase FKBP-type\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_1679 peptidylprolyl isomerase FKBP-type\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_2681 peptidylprolyl isomerase FKBP-type\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_3948 peptidylprolyl isomerase FKBP-type\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_3541 peptidylprolyl isomerase FKBP-type\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_1470 PpiC-type peptidyl-prolyl cis-trans isomerase\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				},
				{
					"name":"Sph21_1480 Thioredoxin domain-containing protein\tK03671 TXN; thioredoxin"
				},
				{
					"name":"Sph21_2911 glutaredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"Sph21_3201 thioredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"Sph21_3592 thioredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"Sph21_3921 thioredoxin\tK03671 TXN; thioredoxin"
				}
				]
			},
			{
				"name":"04131 Membrane trafficking [BR:shg04131]",
				"children":[
				{
					"name":"Sph21_1241 Nucleoside diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"Sph21_4307 glycosyl hydrolase 38 domain protein\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"Sph21_0067 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3255 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3892 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_5090 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_1354 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_2942 major facilitator superfamily MFS_1\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"Sph21_0985 protein of unknown function DUF500\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				}
				]
			},
			{
				"name":"04121 Ubiquitin system [BR:shg04121]"
			},
			{
				"name":"03051 Proteasome [BR:shg03051]",
				"children":[
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"03032 DNA replication proteins [BR:shg03032]",
				"children":[
				{
					"name":"Sph21_3294 Ribonuclease H\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"Sph21_0901 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_3497 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_1129 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_2104 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_0001 Chromosomal replication initiator protein dnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Sph21_3056 replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"Sph21_0670 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_3922 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1712 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2465 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0763 DNA polymerase III gamma\/tau subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3055 Exonuclease RNase T and DNA polymerase III\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3431 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2353 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1167 Ribonuclease H\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Sph21_3360 DNA gyrase, A subunit\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_2460 DNA gyrase, B subunit\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1654 DNA topoisomerase (ATP-hydrolyzing)\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1645 DNA topoisomerase type IIA subunit B region 2 domain protein\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_3174 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Sph21_3683 DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Sph21_3610 DNA topoisomerase III\tK03169 topB; DNA topoisomerase III [EC:5.6.2.1]"
				},
				{
					"name":"Sph21_3672 DNA topoisomerase\tK03169 topB; DNA topoisomerase III [EC:5.6.2.1]"
				}
				]
			},
			{
				"name":"03036 Chromosome and associated proteins [BR:shg03036]",
				"children":[
				{
					"name":"Sph21_0901 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_3497 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_1358 Ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"Sph21_1129 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_2104 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_0783 chaperone DnaJ domain protein\tK05516 cbpA; curved DNA-binding protein"
				},
				{
					"name":"Sph21_0001 Chromosomal replication initiator protein dnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"Sph21_0781 Ferritin Dps family protein\tK04047 dps; starvation-inducible DNA-binding protein"
				},
				{
					"name":"Sph21_4661 Ferritin Dps family protein\tK04047 dps; starvation-inducible DNA-binding protein"
				},
				{
					"name":"Sph21_0528 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_2789 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_4012 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"Sph21_3274 chromosome segregation protein SMC\tK03529 smc; chromosome segregation protein"
				},
				{
					"name":"Sph21_1134 chromosome segregation and condensation protein ScpA\tK05896 scpA; segregation and condensation protein A"
				},
				{
					"name":"Sph21_3051 chromosome segregation and condensation protein, ScpB\tK06024 scpB; segregation and condensation protein B"
				},
				{
					"name":"Sph21_0053 cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"Sph21_3122 Sigma 54 interacting domain protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"Sph21_0061 Peptidoglycan glycosyltransferase\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"Sph21_3876 cell division protein FtsK\/SpoIIIE\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family"
				},
				{
					"name":"Sph21_0054 hypothetical protein\tK03589 ftsQ; cell division protein FtsQ"
				},
				{
					"name":"Sph21_0057 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_0547 protein of unknown function DUF214\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"Sph21_0052 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Sph21_3953 hypothetical protein\tK09888 zapA; cell division protein ZapA"
				},
				{
					"name":"Sph21_2535 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_2536 cell wall hydrolase\/autolysin\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"Sph21_0028 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0421 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1124 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1486 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1696 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2597 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2828 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3603 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3635 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4059 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4634 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4898 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2379 cell shape determining protein, MreB\/Mrl family\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"Sph21_2378 Rod shape-determining protein MreC\tK03570 mreC; rod shape-determining protein MreC"
				},
				{
					"name":"Sph21_2375 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_0428 Cobyrinic acid ac-diamide synthase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Sph21_0427 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Sph21_1654 DNA topoisomerase (ATP-hydrolyzing)\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1645 DNA topoisomerase type IIA subunit B region 2 domain protein\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1300 tRNA uridine 5-carboxymethylaminomethyl modification enzyme mnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"Sph21_2523 Ribosomal RNA small subunit methyltransferase G\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"Sph21_2397 Tyrosine recombinase xerC\tK03733 xerC; integrase\/recombinase XerC"
				},
				{
					"name":"Sph21_0303 integrase family protein\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"Sph21_2551 Tyrosine recombinase xerC\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"Sph21_1365 ATPase-like, ParA\/MinD\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"Sph21_5211 GTP-binding protein engB\tK03978 engB; GTP-binding protein"
				}
				]
			},
			{
				"name":"03400 DNA repair and recombination proteins [BR:shg03400]",
				"children":[
				{
					"name":"Sph21_1680 Deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"Sph21_4011 Uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"Sph21_2724 3-methyladenine DNA glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
				},
				{
					"name":"Sph21_1130 A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"Sph21_0570 endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"Sph21_1546 S1\/P1 nuclease\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"Sph21_2363 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Sph21_2716 NUDIX hydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"Sph21_2783 transcriptional regulator, AraC family\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Sph21_4272 methylated-DNA\/protein-cysteine methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"Sph21_5115 HhH-GPD family protein\tK01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				},
				{
					"name":"Sph21_1495 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_4366 methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_4849 methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"Sph21_3236 DNA-formamidopyrimidine glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
				},
				{
					"name":"Sph21_1390 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Sph21_4521 exodeoxyribonuclease III Xth\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"Sph21_4105 Endonuclease V\tK05982 nfi; deoxyribonuclease V [EC:3.1.21.7]"
				},
				{
					"name":"Sph21_0716 single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_0048 DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"Sph21_1518 DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0558 excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Sph21_5270 excinuclease ABC, A subunit\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"Sph21_0721 UvrABC system protein B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"Sph21_5241 UvrABC system protein C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"Sph21_2931 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3839 UvrD\/REP helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_2406 DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_2407 DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_1742 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"Sph21_1343 transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3063 DNA mismatch repair protein mutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Sph21_5111 DNA mismatch repair protein MutS domain protein\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"Sph21_4670 MutS2 protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"Sph21_1476 DNA mismatch repair protein mutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"Sph21_1456 Exonuclease VII, large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"Sph21_1455 Exodeoxyribonuclease 7 small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"Sph21_3922 DNA polymerase III, alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1712 DNA polymerase III, beta subunit\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2465 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_0763 DNA polymerase III gamma\/tau subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3055 Exonuclease RNase T and DNA polymerase III\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3431 DNA polymerase III, epsilon subunit\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_2353 DNA polymerase III, subunits gamma and tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_0962 DNA mismatch endonuclease Vsr\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_0569 Protein recA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"Sph21_2087 Holliday junction ATP-dependent DNA helicase ruvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"Sph21_2470 Holliday junction ATP-dependent DNA helicase ruvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_1573 Crossover junction endodeoxyribonuclease ruvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"Sph21_0322 primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3865 SMC domain protein\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
				},
				{
					"name":"Sph21_3866 nuclease SbcCD, D subunit\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
				},
				{
					"name":"Sph21_1126 DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
				},
				{
					"name":"Sph21_5257 DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"Sph21_1158 ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_0038 DNA repair protein recO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"Sph21_3097 Recombination protein recR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"Sph21_0396 DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"Sph21_1752 protein of unknown function DUF853 NPT hydrolase\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
				},
				{
					"name":"Sph21_3426 DNA repair protein\tK10979 ku; DNA end-binding protein Ku"
				},
				{
					"name":"Sph21_2578 DNA ligase D\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
				},
				{
					"name":"Sph21_3360 DNA gyrase, A subunit\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_2460 DNA gyrase, B subunit\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_3174 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Sph21_3683 DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"Sph21_1129 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_2104 histone family protein DNA-binding protein\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"Sph21_2937 ATP-dependent DNA helicase, RecQ family\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3364 ATP-dependent DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"Sph21_3197 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3429 DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"Sph21_3244 hypothetical protein\tK14160 imuA; protein ImuA"
				},
				{
					"name":"Sph21_3245 cytosolic protein\tK14161 imuB; protein ImuB"
				},
				{
					"name":"Sph21_4679 regulatory protein RecX\tK03565 recX; regulatory protein"
				},
				{
					"name":"Sph21_4023 PHP domain protein\tK02347 polX; DNA polymerase (family X)"
				},
				{
					"name":"Sph21_1109 DEAD\/H associated domain protein\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"Sph21_0339 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2913 ribonucleoside-diphosphate reductase, alpha subunit\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_0340 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_2914 Ribonucleoside-diphosphate reductase\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"Sph21_1242 phosphoesterase RecJ domain protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			},
			{
				"name":"03029 Mitochondrial biogenesis [BR:shg03029]",
				"children":[
				{
					"name":"Sph21_1608 translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"Sph21_2964 Translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"Sph21_1444 Elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"Sph21_2399 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Sph21_3979 translation elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"Sph21_0363 GTP-binding protein Era-like-protein\tK03595 era; GTPase"
				},
				{
					"name":"Sph21_3907 Tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"Sph21_0546 leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"Sph21_1132 aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"Sph21_1705 glycyl-tRNA synthetase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"Sph21_3007 Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"Sph21_2508 Endonuclease I\tK01173 ENDOG; endonuclease G, mitochondrial"
				},
				{
					"name":"Sph21_1131 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_4628 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_5164 single-strand binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"Sph21_3188 surface antigen (D15)\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Sph21_5201 outer membrane protein assembly complex, YaeT protein\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_3121 Protein grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Sph21_0752 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Sph21_4573 Chaperonin Cpn10\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"Sph21_3120 Chaperone protein dnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"Sph21_3019 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3741 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3997 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_2968 ferredoxin\tK22071 FDX2; ferredoxin-2, mitochondrial"
				},
				{
					"name":"Sph21_1365 ATPase-like, ParA\/MinD\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"Sph21_1557 Protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"Sph21_1556 cytochrome oxidase assembly\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"Sph21_3520 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Sph21_1561 electron transport protein SCO1\/SenC\tK07152 SCO1; protein SCO1"
				},
				{
					"name":"Sph21_3346 electron transport protein SCO1\/SenC\tK07152 SCO1; protein SCO1"
				},
				{
					"name":"Sph21_4299 electron transport protein SCO1\/SenC\tK07152 SCO1; protein SCO1"
				},
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			}
			]
		},
		{
			"name":"09183 Protein families: signaling and cellular processes",
			"children":[
			{
				"name":"02000 Transporters [BR:shg02000]",
				"children":[
				{
					"name":"Sph21_4436 Xenobiotic-transporting ATPase\tK14698 irtA; ATP-binding cassette, subfamily B, bacterial IrtA\/YbtP [EC:7.-.-.-]"
				},
				{
					"name":"Sph21_4435 Xenobiotic-transporting ATPase\tK14699 irtB; ATP-binding cassette, subfamily B, bacterial IrtB\/YbtQ [EC:7.-.-.-]"
				},
				{
					"name":"Sph21_1607 Xenobiotic-transporting ATPase\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]"
				},
				{
					"name":"Sph21_4009 Xenobiotic-transporting ATPase\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Sph21_2417 Xenobiotic-transporting ATPase\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"Sph21_0538 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Sph21_0698 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Sph21_0909 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Sph21_3760 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Sph21_3761 Xenobiotic-transporting ATPase\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"Sph21_0591 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1895 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_4095 Xenobiotic-transporting ATPase\tK20344 blpA; ATP-binding cassette, subfamily C, bacteriocin exporter"
				},
				{
					"name":"Sph21_1301 ABC transporter related protein\tK15738 uup; ABC transport system ATP-binding\/permease protein"
				},
				{
					"name":"Sph21_2284 ABC transporter related protein\tK05776 modF; molybdate transport system ATP-binding protein"
				},
				{
					"name":"Sph21_0814 ABC-type glycine betaine transport, periplasmic subunit\tK02002 proX; glycine betaine\/proline transport system substrate-binding protein"
				},
				{
					"name":"Sph21_0815 ABC-type transporter, integral membrane subunit\tK02001 proW; glycine betaine\/proline transport system permease protein"
				},
				{
					"name":"Sph21_0816 glycine betaine\/L-proline ABC transporter, ATPase subunit\tK02000 proV; glycine betaine\/proline transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"Sph21_2567 ABC-type glycine betaine transport, periplasmic subunit\tK05845 opuC; osmoprotectant transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2568 Fe(3+)-transporting ATPase\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"Sph21_2619 periplasmic binding protein\/LacI transcriptional regulator\tK10439 rbsB; ribose transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2622 ABC-type transporter, integral membrane subunit\tK10440 rbsC; ribose transport system permease protein"
				},
				{
					"name":"Sph21_2621 Monosaccharide-transporting ATPase\tK10441 rbsA; ribose transport system ATP-binding protein [EC:7.5.2.7]"
				},
				{
					"name":"Sph21_2534 Mammalian cell entry related domain protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"Sph21_3069 Mammalian cell entry related domain protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"Sph21_1668 protein of unknown function DUF140\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"Sph21_3067 protein of unknown function DUF140\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"Sph21_1667 Sulfate-transporting ATPase\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3068 Sulfate-transporting ATPase\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"Sph21_2339 extracellular solute-binding protein family 1\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Sph21_2342 extracellular solute-binding protein family 1\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4532 ABC-type phosphate transporter substrate-binding component\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4735 phosphate binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4531 phosphate ABC transporter, inner membrane subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4734 phosphate ABC transporter, inner membrane subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4530 ABC-type transporter, integral membrane subunit\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4733 phosphate ABC transporter, inner membrane subunit PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"Sph21_4529 Phosphate-transporting ATPase\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Sph21_4732 phosphate ABC transporter, ATPase subunit\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"Sph21_4537 lipoprotein, YaeC family\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"Sph21_4538 ABC-type transporter, integral membrane subunit\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"Sph21_4539 Phosphonate-transporting ATPase\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3278 ABC transporter substrate binding protein\tK01989 K01989; putative tryptophan\/tyrosine transport system substrate-binding protein"
				},
				{
					"name":"Sph21_3279 ABC-type transporter, integral membrane subunit\tK05832 K05832; putative tryptophan\/tyrosine transport system permease protein"
				},
				{
					"name":"Sph21_3280 Phosphonate-transporting ATPase\tK05833 K05833; putative tryptophan\/tyrosine transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3700 ABC-type transporter, periplasmic subunit\tK25132 hmuT; heme transport system substrate-binding protein"
				},
				{
					"name":"Sph21_3701 ABC-type transporter, integral membrane subunit\tK25133 hmuU; heme transport system permease protein"
				},
				{
					"name":"Sph21_3702 Phosphonate-transporting ATPase\tK10834 hmuV; heme transport system ATP-binding protein [EC:7.6.2.5]"
				},
				{
					"name":"Sph21_0411 hypothetical protein\tK02016 ABC.FEV.S; iron complex transport system substrate-binding protein"
				},
				{
					"name":"Sph21_0564 permease YjgP\/YjgQ family protein\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Sph21_2520 permease YjgP\/YjgQ family protein\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"Sph21_0715 Sulfate-transporting ATPase\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Sph21_4999 ABC transporter related protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"Sph21_1709 gliding-associated putative ABC transporter substrate-binding component GldG\tK25151 gldF; gliding motility-associated transport system permease protein"
				},
				{
					"name":"Sph21_1707 Sulfate-transporting ATPase\tK25152 gldA; gliding motility-associated transport system ATP-binding protein"
				},
				{
					"name":"Sph21_4079 ABC-2 type transporter\tK25180 ybhR; drug efflux transport system permease protein"
				},
				{
					"name":"Sph21_4080 ABC-2 type transporter\tK25181 ybhS; drug efflux transport system permease protein"
				},
				{
					"name":"Sph21_4081 Sulfate-transporting ATPase\tK25182 ybhF; drug efflux transport system ATP-binding protein"
				},
				{
					"name":"Sph21_4082 Sulfate-transporting ATPase\tK25182 ybhF; drug efflux transport system ATP-binding protein"
				},
				{
					"name":"Sph21_4083 biotin\/lipoyl attachment domain-containing protein\tK25183 ybhG; membrane fusion protein YbhG"
				},
				{
					"name":"Sph21_1342 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Sph21_3547 protein of unknown function DUF214\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"Sph21_3281 Polyamine-transporting ATPase\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"Sph21_2981 cytochrome c assembly protein\tK02195 ccmC; heme exporter protein C"
				},
				{
					"name":"Sph21_2980 cytochrome c-type biogenesis protein CcmB\tK02194 ccmB; heme exporter protein B"
				},
				{
					"name":"Sph21_0547 protein of unknown function DUF214\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"Sph21_3122 Sigma 54 interacting domain protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"Sph21_2719 ABC-type transport, permease protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"Sph21_3117 ABC transporter, permease protein, putative\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"Sph21_3766 membrane protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"Sph21_0787 Fe(3+)-transporting ATPase\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Sph21_2718 Phosphonate-transporting ATPase\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3118 Fe(3+)-transporting ATPase\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3767 ABC transporter related protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"Sph21_0828 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_0844 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_0965 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1069 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1176 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1177 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1178 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1179 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1198 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1199 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1200 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1209 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1210 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1214 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1221 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1225 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1226 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1227 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1228 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_2591 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_2610 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_3413 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_3990 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_4314 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_4358 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_4388 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_4774 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_4981 protein of unknown function DUF214\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"Sph21_1175 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Sph21_1229 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Sph21_2590 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3414 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Sph21_3516 Phosphonate-transporting ATPase\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"Sph21_4016 FeS assembly ATPase SufC\tK09013 sufC; Fe-S cluster assembly ATP-binding protein"
				},
				{
					"name":"Sph21_1223 MATE efflux family protein\tK26939 norM; MATE family, multidrug efflux pump"
				},
				{
					"name":"Sph21_1448 MATE efflux family protein\tK26939 norM; MATE family, multidrug efflux pump"
				},
				{
					"name":"Sph21_0109 sugar transporter\tK02100 araE; MFS transporter, SP family, arabinose:H+ symporter"
				},
				{
					"name":"Sph21_4246 sugar transporter\tK02100 araE; MFS transporter, SP family, arabinose:H+ symporter"
				},
				{
					"name":"Sph21_4794 sugar transporter\tK02100 araE; MFS transporter, SP family, arabinose:H+ symporter"
				},
				{
					"name":"Sph21_0611 L-fucose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_0624 L-fucose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_1439 glucose\/galactose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_2345 L-fucose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_2845 glucose\/galactose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_4108 glucose\/galactose transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"Sph21_3058 nucleoside transporter\tK11537 xapB; MFS transporter, NHS family, xanthosine permease"
				},
				{
					"name":"Sph21_2391 General substrate transporter\tK03761 kgtP; MFS transporter, MHS family, alpha-ketoglutarate permease"
				},
				{
					"name":"Sph21_2895 major facilitator superfamily MFS_1\tK08191 exuT; MFS transporter, ACS family, aldohexuronate transporter"
				},
				{
					"name":"Sph21_4582 major facilitator superfamily MFS_1\tK08194 dgoT; MFS transporter, ACS family, D-galactonate transporter"
				},
				{
					"name":"Sph21_3753 major facilitator superfamily MFS_1\tK02575 NRT2; MFS transporter, NNP family, nitrate\/nitrite transporter"
				},
				{
					"name":"Sph21_0362 major facilitator superfamily MFS_1\tK08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein"
				},
				{
					"name":"Sph21_0952 major facilitator superfamily MFS_1\tK07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_1192 major facilitator superfamily MFS_1\tK08156 araJ; MFS transporter, DHA1 family, arabinose polymer utilization protein"
				},
				{
					"name":"Sph21_0890 hypothetical protein\tK03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_1676 drug resistance transporter, EmrB\/QacA subfamily\tK03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_1760 hypothetical protein\tK03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_3688 drug resistance transporter, EmrB\/QacA subfamily\tK03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_4862 hypothetical protein\tK03446 emrB; MFS transporter, DHA2 family, multidrug resistance protein"
				},
				{
					"name":"Sph21_4553 major facilitator superfamily MFS_1\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				},
				{
					"name":"Sph21_3853 major facilitator superfamily MFS_1\tK08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein"
				},
				{
					"name":"Sph21_2942 major facilitator superfamily MFS_1\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"Sph21_5112 MIP family channel protein\tK06188 aqpZ; aquaporin"
				},
				{
					"name":"Sph21_2907 major intrinsic protein\tK02440 glpF; glycerol uptake facilitator"
				},
				{
					"name":"Sph21_2213 ammonium transporter\tK03320 amt; ammonium transporter, Amt family"
				},
				{
					"name":"Sph21_3223 ammonium transporter\tK03320 amt; ammonium transporter, Amt family"
				},
				{
					"name":"Sph21_0643 von Willebrand factor type A\tK07114 yfbK; Ca-activated chloride channel homolog"
				},
				{
					"name":"Sph21_1186 von Willebrand factor type A\tK07114 yfbK; Ca-activated chloride channel homolog"
				},
				{
					"name":"Sph21_3746 formate\/nitrite transporter\tK21993 fdhC; formate transporter"
				},
				{
					"name":"Sph21_0329 Large-conductance mechanosensitive channel\tK03282 mscL; large conductance mechanosensitive channel"
				},
				{
					"name":"Sph21_2838 MscS Mechanosensitive ion channel\tK05802 mscK; potassium-dependent mechanosensitive channel"
				},
				{
					"name":"Sph21_4028 MscS Mechanosensitive ion channel\tK03442 mscS; small conductance mechanosensitive channel"
				},
				{
					"name":"Sph21_0671 MscS Mechanosensitive ion channel\tK16053 ybdG; miniconductance mechanosensitive channel"
				},
				{
					"name":"Sph21_3970 magnesium transporter\tK06213 mgtE; magnesium transporter"
				},
				{
					"name":"Sph21_4296 magnesium transporter\tK06213 mgtE; magnesium transporter"
				},
				{
					"name":"Sph21_1580 MotA\/TolQ\/ExbB proton channel\tK03561 exbB; biopolymer transport protein ExbB"
				},
				{
					"name":"Sph21_2226 MotA\/TolQ\/ExbB proton channel\tK03561 exbB; biopolymer transport protein ExbB"
				},
				{
					"name":"Sph21_2225 Biopolymer transport protein ExbD\/TolR\tK03559 exbD; biopolymer transport protein ExbD"
				},
				{
					"name":"Sph21_2078 Mg2 transporter protein CorA family protein\tK03284 corA; magnesium transporter"
				},
				{
					"name":"Sph21_1335 hypothetical protein\tK08994 yneE; ion channel-forming bestrophin family protein"
				},
				{
					"name":"Sph21_2916 hypothetical protein\tK08994 yneE; ion channel-forming bestrophin family protein"
				},
				{
					"name":"Sph21_3974 hypothetical protein\tK08994 yneE; ion channel-forming bestrophin family protein"
				},
				{
					"name":"Sph21_1603 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"Sph21_3679 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"Sph21_0352 phosphate-selective porin O and P\tK07221 oprO_P; phosphate-selective porin OprO and OprP"
				},
				{
					"name":"Sph21_1156 OmpA\/MotB domain protein\tK03286 TC.OOP; OmpA-OmpF porin, OOP family"
				},
				{
					"name":"Sph21_3211 OmpA\/MotB domain protein\tK03286 TC.OOP; OmpA-OmpF porin, OOP family"
				},
				{
					"name":"Sph21_3650 TonB-dependent receptor\tK16092 btuB; vitamin B12 transporter"
				},
				{
					"name":"Sph21_3961 TonB-dependent receptor\tK16092 btuB; vitamin B12 transporter"
				},
				{
					"name":"Sph21_0388 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0460 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0477 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0497 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0583 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0929 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1008 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1279 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1419 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1662 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1900 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1967 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_1990 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2054 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2267 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2372 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2649 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2660 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2779 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2842 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2857 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2888 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2905 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_2949 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_3882 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_3902 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_3925 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4245 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4291 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4309 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4707 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4722 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4760 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4798 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_4803 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_5060 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_5087 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_5121 TonB-dependent receptor plug\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_5123 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"Sph21_0222 TonB-dependent receptor plug\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"Sph21_2773 TonB-dependent receptor plug\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"Sph21_3699 TonB-dependent receptor\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"Sph21_0139 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_0924 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_1011 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_1184 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_1248 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2111 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2546 outer membrane insertion C-terminal signal\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2549 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2572 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2676 TonB-dependent receptor plug\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_2683 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_3131 TonB-dependent receptor plug\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_3398 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_5065 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_5107 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_5170 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"Sph21_3967 outer membrane efflux protein\tK15725 czcC; outer membrane protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_0287 outer membrane protein-like protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2804 outer membrane protein-like protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0423 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1488 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2599 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2826 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4896 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1809 Soluble ligand binding domain\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_1958 polysaccharide export protein\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_2025 Soluble ligand binding domain\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"Sph21_3188 surface antigen (D15)\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Sph21_5201 outer membrane protein assembly complex, YaeT protein\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"Sph21_1764 outer membrane assembly lipoprotein YfiO\tK05807 bamD; outer membrane protein assembly factor BamD"
				},
				{
					"name":"Sph21_3898 major facilitator superfamily MFS_1\tK16211 malY; maltose\/moltooligosaccharide transporter"
				},
				{
					"name":"Sph21_3777 amino acid permease-associated region\tK11734 aroP; aromatic amino acid transport protein AroP"
				},
				{
					"name":"Sph21_0667 ethanolamine transporter\tK16238 eat; ethanolamine permease"
				},
				{
					"name":"Sph21_4000 zinc\/iron permease\tK16267 zipB; zinc and cadmium transporter"
				},
				{
					"name":"Sph21_0225 heavy metal efflux pump, CzcA family\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"Sph21_0894 heavy metal efflux pump, CzcA family\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"Sph21_3351 heavy metal efflux pump, CzcA family\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"Sph21_3665 heavy metal efflux pump, CzcA family\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"Sph21_3969 heavy metal efflux pump, CzcA family\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"Sph21_0288 acriflavin resistance protein\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"Sph21_2805 acriflavin resistance protein\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"Sph21_0029 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0422 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1123 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1487 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1695 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2598 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2827 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3602 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3636 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4058 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4633 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4897 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3287 small multidrug resistance protein\tK11741 sugE; quaternary ammonium compound-resistance protein SugE"
				},
				{
					"name":"Sph21_0517 RhaT l-rhamnose-proton symport 2\tK02856 rhaT; L-rhamnose-H+ transport protein"
				},
				{
					"name":"Sph21_4236 RarD protein, DMT superfamily transporter\tK05786 rarD; chloramphenicol-sensitive protein RarD"
				},
				{
					"name":"Sph21_5125 gluconate transporter\tK06155 gntT; Gnt-I system high-affinity gluconate transporter"
				},
				{
					"name":"Sph21_4418 L-lactate transport\tK03303 lutP; lactate permease"
				},
				{
					"name":"Sph21_3249 choline\/carnitine\/betaine transporter\tK02168 betT; choline\/glycine\/proline betaine transport protein"
				},
				{
					"name":"Sph21_1231 sodium:dicarboxylate symporter\tK11103 dctA; aerobic C4-dicarboxylate transport protein"
				},
				{
					"name":"Sph21_0081 Na(+)\/H(+) antiporter nhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family"
				},
				{
					"name":"Sph21_3226 Na(+)\/H(+) antiporter nhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family"
				},
				{
					"name":"Sph21_2575 Na+\/H+ antiporter\tK24163 nhaK; monovalent cation\/hydrogen antiporter"
				},
				{
					"name":"Sph21_2791 Na+\/H+ antiporter\tK24163 nhaK; monovalent cation\/hydrogen antiporter"
				},
				{
					"name":"Sph21_2242 sodium\/hydrogen exchanger\tK03316 nhaP; Na+:H+ antiporter"
				},
				{
					"name":"Sph21_3145 sodium\/hydrogen exchanger\tK26730 napA; Na+:H+ antiporter"
				},
				{
					"name":"Sph21_3856 sodium\/hydrogen exchanger\tK26731 CHX; K+:H+ antiporter"
				},
				{
					"name":"Sph21_5266 TrkA-C domain protein\tK07228 khtT; K+:H+ antiporter subunit KhtT"
				},
				{
					"name":"Sph21_5267 sodium\/hydrogen exchanger\tK26732 khtU; K+:H+ antiporter subunit KhtU"
				},
				{
					"name":"Sph21_0179 Cl-channel voltage-gated family protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"Sph21_3022 Cl-channel voltage-gated family protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"Sph21_3235 Cl-channel voltage-gated family protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"Sph21_5099 Chromate transporter\tK07240 chrA; chromate transporter"
				},
				{
					"name":"Sph21_5100 Chromate transporter\tK07240 chrA; chromate transporter"
				},
				{
					"name":"Sph21_0301 sulfate transporter\tK03321 TC.SULP; sulfate permease, SulP family"
				},
				{
					"name":"Sph21_2702 sulphate transporter\tK03321 TC.SULP; sulfate permease, SulP family"
				},
				{
					"name":"Sph21_2367 Manganese transport protein mntH\tK03322 mntH; manganese transport protein"
				},
				{
					"name":"Sph21_0231 arsenical-resistance protein\tK03325 ACR3; arsenite transporter"
				},
				{
					"name":"Sph21_4778 arsenical-resistance protein\tK03325 ACR3; arsenite transporter"
				},
				{
					"name":"Sph21_3008 NADH dehydrogenase (quinone)\tK05565 mnhA; multicomponent Na+:H+ antiporter subunit A"
				},
				{
					"name":"Sph21_3009 Na+\/H+ antiporter MnhB subunit-related protein\tK05566 mnhB; multicomponent Na+:H+ antiporter subunit B"
				},
				{
					"name":"Sph21_3010 NADH-ubiquinone oxidoreductase chain 4L\tK05567 mnhC; multicomponent Na+:H+ antiporter subunit C"
				},
				{
					"name":"Sph21_3011 NADH dehydrogenase (quinone)\tK05568 mnhD; multicomponent Na+:H+ antiporter subunit D"
				},
				{
					"name":"Sph21_3012 cation antiporter\tK05569 mnhE; multicomponent Na+:H+ antiporter subunit E"
				},
				{
					"name":"Sph21_3013 multiple resistance and pH regulation protein F\tK05570 mnhF; multicomponent Na+:H+ antiporter subunit F"
				},
				{
					"name":"Sph21_3014 monovalent cation\/proton antiporter, MnhG\/PhaG subunit\tK05571 mnhG; multicomponent Na+:H+ antiporter subunit G"
				},
				{
					"name":"Sph21_5056 Auxin Efflux Carrier\tK24180 mleP; malate permease and related proteins"
				},
				{
					"name":"Sph21_3910 Low affinity potassium transport system protein kup\tK03549 kup; KUP system potassium uptake protein"
				},
				{
					"name":"Sph21_2243 multiple antibiotic resistance (MarC)-related protein\tK05595 marC; multiple antibiotic resistance protein"
				},
				{
					"name":"Sph21_0057 cell cycle protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"Sph21_1911 carbon starvation protein CstA\tK06200 cstA; carbon starvation protein"
				},
				{
					"name":"Sph21_1583 TonB family protein\tK03832 tonB; periplasmic protein TonB"
				},
				{
					"name":"Sph21_3333 TonB family protein\tK03832 tonB; periplasmic protein TonB"
				},
				{
					"name":"Sph21_3844 OmpA\/MotB domain protein\tK03640 pal; peptidoglycan-associated lipoprotein"
				},
				{
					"name":"Sph21_2245 Pyrophosphate-energized proton pump\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]"
				},
				{
					"name":"Sph21_0889 secretion protein HlyD family protein\tK03543 emrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1675 secretion protein HlyD family protein\tK03543 emrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1759 secretion protein HlyD family protein\tK03543 emrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4863 secretion protein HlyD family protein\tK03543 emrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0226 efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_0893 efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_3353 efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_3664 efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_3968 efflux transporter, RND family, MFP subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"Sph21_0285 efflux transporter, RND family, MFP subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0286 hypothetical protein\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2802 efflux transporter, RND family, MFP subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_2803 hypothetical protein\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"Sph21_0028 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0421 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1124 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1486 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1696 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2597 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2828 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3603 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3635 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4059 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4634 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4898 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1896 secretion protein HlyD family protein\tK20345 blpB; membrane fusion protein, peptide pheromone\/bacteriocin exporter"
				},
				{
					"name":"Sph21_4094 secretion protein HlyD family protein\tK20345 blpB; membrane fusion protein, peptide pheromone\/bacteriocin exporter"
				},
				{
					"name":"Sph21_1810 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_1959 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_2026 capsular exopolysaccharide family\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"Sph21_0089 tetratricopeptide domain protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0106 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0153 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0193 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0265 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0389 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0432 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0459 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0476 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0479 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0481 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0491 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0496 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0582 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0601 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0616 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0632 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0635 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0802 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0809 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0840 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0928 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_0940 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1001 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1003 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1007 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1013 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1094 RagB\/SusD domain protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1096 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1262 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1278 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1420 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1648 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1661 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1773 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1775 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1853 hypothetical protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1872 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1880 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1883 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1886 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1899 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1921 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1929 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1968 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1976 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_1991 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2055 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2268 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2307 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2331 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2357 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2371 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2495 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2630 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2650 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2659 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2747 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2751 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2780 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2836 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2843 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2856 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2862 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2887 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2889 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2904 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2941 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2948 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_2950 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3263 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3267 hypothetical protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3881 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3901 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3926 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4235 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4244 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4249 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4262 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4290 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4308 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4332 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4416 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4467 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4698 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4708 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4721 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4747 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4761 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4797 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4802 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4860 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_4916 hypothetical protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5017 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5059 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5086 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5122 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5124 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_5172 RagB\/SusD domain-containing protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"Sph21_3670 nicotinamide mononucleotide transporter PnuC\tK03811 pnuC; nicotinamide mononucleotide transporter"
				},
				{
					"name":"Sph21_2199 FeoA family protein\tK04758 feoA; ferrous iron transport protein A"
				},
				{
					"name":"Sph21_2200 ferrous iron transport protein B\tK04759 feoB; ferrous iron transport protein B"
				},
				{
					"name":"Sph21_3138 cytochrome c assembly protein\tK02198 ccmF; cytochrome c-type biogenesis protein CcmF"
				},
				{
					"name":"Sph21_3774 MgtC\/SapB transporter\tK07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein"
				},
				{
					"name":"Sph21_5268 MgtC\/SapB transporter\tK07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein"
				},
				{
					"name":"Sph21_4312 protein of unknown function DUF202\tK00389 yidH; inner membrane protein YidH"
				}
				]
			},
			{
				"name":"02044 Secretion system [BR:shg02044]",
				"children":[
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_2216 CMP\/dCMP deaminase zinc-binding protein\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"Sph21_2936 ComEC\/Rec2-related protein\tK02238 comEC; competence protein ComEC"
				},
				{
					"name":"Sph21_0674 Protein translocase subunit secA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"Sph21_2971 protein-export membrane protein SecD\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"Sph21_2400 preprotein translocase, SecE subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"Sph21_0751 preprotein translocase, SecG subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"Sph21_1735 preprotein translocase, SecY subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"Sph21_1442 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"Sph21_5185 signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"Sph21_4005 preprotein translocase, YajC subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"Sph21_3520 Membrane protein oxaA\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"Sph21_1145 twin-arginine translocation protein, TatA\/E family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2075 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_2540 Sec-independent protein translocase protein tatA\/E-like protein\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"Sph21_0014 Sec-independent protein translocase, TatC subunit\tK03118 tatC; sec-independent protein translocase protein TatC"
				}
				]
			},
			{
				"name":"02042 Bacterial toxins [BR:shg02042]",
				"children":[
				{
					"name":"Sph21_1603 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"Sph21_3679 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"Sph21_0662 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"Sph21_1769 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				}
				]
			},
			{
				"name":"02022 Two-component system [BR:shg02022]",
				"children":[
				{
					"name":"Sph21_1333 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1369 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4070 integral membrane sensor signal transduction histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1570 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Sph21_3108 two component transcriptional regulator, winged helix family\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"Sph21_4258 Osmosensitive K channel His kinase sensor\tK07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_1638 two component transcriptional regulator, winged helix family\tK02483 K02483; two-component system, OmpR family, response regulator"
				},
				{
					"name":"Sph21_4504 response regulator receiver sensor signal transduction histidine kinase\tK07675 uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2076 integral membrane sensor signal transduction histidine kinase\tK07677 rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4952 response regulator receiver protein\tK07687 rcsB; two-component system, NarL family, captular synthesis response regulator RcsB"
				},
				{
					"name":"Sph21_2093 two component transcriptional regulator, LuxR family\tK07689 uvrY; two-component system, NarL family, invasion response regulator UvrY"
				},
				{
					"name":"Sph21_3744 two component transcriptional regulator, LuxR family\tK07692 degU; two-component system, NarL family, response regulator DegU"
				},
				{
					"name":"Sph21_3206 two component transcriptional regulator, LuxR family\tK07696 nreC; two-component system, NarL family, response regulator NreC"
				},
				{
					"name":"Sph21_0874 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2387 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_3408 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4640 signal transduction histidine kinase, LytS\tK02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_0130 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0258 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0653 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0694 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0855 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0873 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_0967 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_1398 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_1859 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_2098 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_2386 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_3208 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_3409 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4045 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4224 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4376 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4477 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4641 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_4745 two component transcriptional regulator, LytTR family\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"Sph21_1172 two component, sigma54 specific, transcriptional regulator, Fis family\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"Sph21_3147 two component, sigma54 specific, transcriptional regulator, Fis family\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"Sph21_4259 multi-sensor signal transduction histidine kinase\tK11383 kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2045 multi-sensor signal transduction multi-kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_4268 two component, sigma54 specific, transcriptional regulator, Fis family\tK02481 flgR; two-component system, NtrC family, response regulator"
				},
				{
					"name":"Sph21_2096 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2923 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2156 signal transduction histidine kinase with CheB and CheR activity\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]"
				},
				{
					"name":"Sph21_2157 putative PAS\/PAC sensor protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				},
				{
					"name":"Sph21_2355 Diverse 7TM receptor transmembrane region\tK20971 ladS; two-component system, sensor histidine kinase LadS"
				},
				{
					"name":"Sph21_1112 response regulator receiver sensor signal transduction histidine kinase\tK11527 K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"02035 Bacterial motility proteins [BR:shg02035]",
				"children":[
				{
					"name":"Sph21_1115 MCP methyltransferase, CheR-type\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"Sph21_2096 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2923 CheB methylesterase\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"Sph21_2156 signal transduction histidine kinase with CheB and CheR activity\tK13924 cheBR; two-component system, chemotaxis family, CheB\/CheR fusion protein [EC:2.1.1.80 3.1.1.61]"
				}
				]
			},
			{
				"name":"03037 Cilium and associated proteins"
			},
			{
				"name":"04812 Cytoskeleton proteins [BR:shg04812]",
				"children":[
				{
					"name":"Sph21_2379 cell shape determining protein, MreB\/Mrl family\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"Sph21_0052 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Sph21_0053 cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"Sph21_0428 Cobyrinic acid ac-diamide synthase\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"Sph21_0427 parB-like partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				}
				]
			},
			{
				"name":"04147 Exosome [BR:shg04147]",
				"children":[
				{
					"name":"Sph21_2810 HSP90 family protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_3254 Heat shock protein Hsp90\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"Sph21_0335 Enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"Sph21_0067 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3255 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_3892 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_5090 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"Sph21_0066 Phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"Sph21_1354 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"Sph21_1081 Membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Sph21_2875 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Sph21_1481 Peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
				},
				{
					"name":"Sph21_0753 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"Sph21_1745 Chaperone protein dnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"Sph21_0676 Glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"Sph21_0993 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_2473 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_1253 Gluconolactonase\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_4037 SMP-30\/Gluconolaconase\/LRE-like region-containing protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"Sph21_3644 inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"Sph21_2399 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"Sph21_1572 histidine triad (HIT) protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"Sph21_0025 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_3308 Long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"Sph21_2475 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"Sph21_1238 Adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"Sph21_0074 Adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"Sph21_2249 Adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"Sph21_1042 Argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"Sph21_1034 argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"Sph21_4650 Cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"Sph21_3143 Fructose-1,6-bisphosphatase class 1\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"Sph21_0603 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0657 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_0729 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_1768 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2056 coagulation factor 5\/8 type domain protein\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2166 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2860 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2863 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_2868 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3373 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_3374 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4700 Alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_4801 glycoside hydrolase family 29 (alpha-L-fucosidase)\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"Sph21_1349 Galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"Sph21_2180 1,4-alpha-glucan-branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"Sph21_5139 1,4-alpha-glucan-branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"Sph21_2623 Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Sph21_2908 Glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"Sph21_0666 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_3985 Glutamate--ammonia ligase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"Sph21_5196 Porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
				},
				{
					"name":"Sph21_2825 transcriptional coactivator\/pterin dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
				},
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_0005 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0434 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_0741 amino acid-binding ACT domain protein\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_3091 Phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"Sph21_2382 phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"Sph21_1690 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3439 dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"Sph21_3060 Electron transfer flavoprotein alpha subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
				},
				{
					"name":"Sph21_2983 Glutamate dehydrogenase (NAD(P)(+))\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"Sph21_4277 glucose-6-phosphate 1-dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
				},
				{
					"name":"Sph21_3045 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				}
				]
			},
			{
				"name":"02048 Prokaryotic defense system [BR:shg02048]",
				"children":[
				{
					"name":"Sph21_0901 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_3497 C-5 cytosine-specific DNA methylase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"Sph21_0585 Domain of unknown function DUF1813 HSP20-like protein\tK19048 symE; toxic protein SymE"
				},
				{
					"name":"Sph21_2679 addiction module toxin, Txe\/YoeB family\tK19158 yoeB; toxin YoeB [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_0442 transcriptional regulator, XRE family\tK18831 higA; HTH-type transcriptional regulator \/ antitoxin HigA"
				},
				{
					"name":"Sph21_4405 PilT protein domain protein\tK18828 mvpA; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]"
				},
				{
					"name":"Sph21_0052 cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"Sph21_2379 cell shape determining protein, MreB\/Mrl family\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"Sph21_1654 DNA topoisomerase (ATP-hydrolyzing)\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1645 DNA topoisomerase type IIA subunit B region 2 domain protein\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"Sph21_1436 glutamyl-tRNA synthetase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"Sph21_3019 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3741 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"Sph21_3997 Cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"04030 G protein-coupled receptors"
			},
			{
				"name":"04050 Cytokine receptors"
			},
			{
				"name":"04054 Pattern recognition receptors"
			},
			{
				"name":"03310 Nuclear receptors"
			},
			{
				"name":"04040 Ion channels [BR:shg04040]"
			},
			{
				"name":"04031 GTP-binding proteins"
			},
			{
				"name":"04052 Cytokines and neuropeptides"
			},
			{
				"name":"04515 Cell adhesion molecules"
			},
			{
				"name":"04090 CD molecules [BR:shg04090]",
				"children":[
				{
					"name":"Sph21_0993 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"Sph21_2473 Dipeptidyl-peptidase IV\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				}
				]
			},
			{
				"name":"01504 Antimicrobial resistance genes [BR:shg01504]",
				"children":[
				{
					"name":"Sph21_2136 GCN5-related N-acetyltransferase\tK03395 aac3-I; aminoglycoside 3-N-acetyltransferase I [EC:2.3.1.60]"
				},
				{
					"name":"Sph21_3199 adenylyltransferase\tK05593 aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]"
				},
				{
					"name":"Sph21_0362 major facilitator superfamily MFS_1\tK08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein"
				},
				{
					"name":"Sph21_4553 major facilitator superfamily MFS_1\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				},
				{
					"name":"Sph21_1822 hypothetical protein\tK18234 vat; virginiamycin A acetyltransferase [EC:2.3.1.-]"
				},
				{
					"name":"Sph21_3786 Chloramphenicol O-acetyltransferase\tK19271 catA; chloramphenicol O-acetyltransferase type A [EC:2.3.1.28]"
				},
				{
					"name":"Sph21_4488 chloramphenicol acetyltransferase\tK19271 catA; chloramphenicol O-acetyltransferase type A [EC:2.3.1.28]"
				},
				{
					"name":"Sph21_1235 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_1402 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_3629 peptidase M56 BlaR1\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"Sph21_1236 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_1401 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_3628 transcriptional repressor, CopY family\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Sph21_4054 Lysylphosphatidylglycerol synthetase\/UPF0104\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				},
				{
					"name":"Sph21_0028 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0421 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1124 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1486 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1696 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2597 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2828 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3603 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_3635 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4059 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4634 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4898 efflux transporter, RND family, MFP subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0029 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0422 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1123 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1487 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_1695 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2598 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_2827 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3602 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_3636 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4058 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4633 acriflavin resistance protein\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_4897 transporter, hydrophobe\/amphiphile efflux-1 (HAE1) family\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"Sph21_0423 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_1488 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2599 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_2826 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_4896 RND efflux system, outer membrane lipoprotein, NodT family\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"Sph21_0030 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_0888 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1232 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1674 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1697 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_1758 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3416 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3601 putative outer membrane protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_3634 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4057 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4138 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4635 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"Sph21_4864 outer membrane efflux protein\tK12340 tolC; outer membrane protein"
				}
				]
			},
			{
				"name":"00535 Proteoglycans"
			},
			{
				"name":"00536 Glycosaminoglycan binding proteins"
			},
			{
				"name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:shg00537]",
				"children":[
				{
					"name":"Sph21_0968 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_2898 Alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"Sph21_1252 Alpha,alpha-trehalase\tK01194 TREH; alpha,alpha-trehalase [EC:3.2.1.28]"
				},
				{
					"name":"Sph21_1081 Membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"Sph21_2875 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				}
				]
			},
			{
				"name":"04091 Lectins"
			},
			{
				"name":"04990 Domain-containing proteins not elsewhere classified"
			}
			]
		},
		{
			"name":"09185 Viral protein families",
			"children":[
			{
				"name":"03200 Viral proteins"
			},
			{
				"name":"03210 Viral fusion proteins"
			}
			]
		},
		{
			"name":"09184 RNA family",
			"children":[
			{
				"name":"03100 Non-coding RNAs [BR:shg03100]",
				"children":[
				{
					"name":"Sph21_R0023 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0036 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0066 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"Sph21_R0003 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0020 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0049 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"Sph21_R0021 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"Sph21_R0018 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Sph21_R0019 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"Sph21_R0022 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0046 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0058 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0062 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"Sph21_R0063 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"Sph21_R0004 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Sph21_R0005 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"Sph21_R0028 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0055 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0060 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"Sph21_R0033 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"Sph21_R0008 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0014 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0035 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0067 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"Sph21_R0040 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0053 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0054 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0061 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"Sph21_R0050 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0051 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0052 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"Sph21_R0010 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0011 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"Sph21_R0025 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"Sph21_R0016 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0017 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0057 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0059 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"Sph21_R0031 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0039 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0043 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0056 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"Sph21_R0026 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0029 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0042 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"Sph21_R0030 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"Sph21_R0027 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"Sph21_R0001 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_R0002 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_R0032 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"Sph21_R0009 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0034 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0068 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"Sph21_R0007 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0013 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0037 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0065 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"Sph21_R0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0038 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0064 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"Sph21_R0048 rnpB; RNA component of RNaseP\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"Sph21_R0047 ssrA; tmRNA as predicted by Rfam (RF00023), score 128.59\tK15035 ssrA; transfer-messenger RNA"
				},
				{
					"name":"Sph21_R0045 ffs; SRP RNA; RNA component of signal recognition particle\tK01983 ffs; signal recognition particle 4.5S RNA"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"09190 Not Included in Pathway or Brite",
		"children":[
		{
			"name":"09191 Unclassified: metabolism",
			"children":[
			{
				"name":"99980 Enzymes with EC numbers",
				"children":[
				{
					"name":"Sph21_0127 Methylglyoxal reductase (NADPH-dependent)\tK06221 dkgA; 2,5-diketo-D-gluconate reductase A [EC:1.1.1.346]"
				},
				{
					"name":"Sph21_0981 4-hydroxythreonine-4-phosphate dehydrogenase\tK22024 pdxA2; 4-phospho-D-threonate 3-dehydrogenase \/ 4-phospho-D-erythronate 3-dehydrogenase [EC:1.1.1.408 1.1.1.409]"
				},
				{
					"name":"Sph21_3423 NADP-dependent oxidoreductase domain\tK19265 gpr; L-glyceraldehyde 3-phosphate reductase [EC:1.1.1.-]"
				},
				{
					"name":"Sph21_0176 glucose-methanol-choline oxidoreductase\tK26059 gtd1; glucoside 3-dehydrogenase (cytochrome c) catalytic subunit [EC:1.1.2.11]"
				},
				{
					"name":"Sph21_3642 glucose-methanol-choline oxidoreductase\tK26059 gtd1; glucoside 3-dehydrogenase (cytochrome c) catalytic subunit [EC:1.1.2.11]"
				},
				{
					"name":"Sph21_4576 glucose sorbosone dehydrogenase\tK21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]"
				},
				{
					"name":"Sph21_1047 short-chain dehydrogenase\/reductase SDR\tK11166 DHRS7B; dehydrogenase\/reductase SDR family member 7B [EC:1.1.-.-]"
				},
				{
					"name":"Sph21_0135 Isoquinoline 1-oxidoreductase\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_4281 Isoquinoline 1-oxidoreductase\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_4754 Isoquinoline 1-oxidoreductase\tK07302 iorA; isoquinoline 1-oxidoreductase subunit alpha [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_0134 Aldehyde dehydrogenase (pyrroloquinoline-quinone)\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_4282 Aldehyde dehydrogenase (pyrroloquinoline-quinone)\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_4756 Isoquinoline 1-oxidoreductase\tK07303 iorB; isoquinoline 1-oxidoreductase subunit beta [EC:1.3.99.16]"
				},
				{
					"name":"Sph21_0187 NADP oxidoreductase coenzyme F420-dependent\tK06988 fno; 8-hydroxy-5-deazaflavin:NADPH oxidoreductase [EC:1.5.1.40]"
				},
				{
					"name":"Sph21_2665 NAD(P)H dehydrogenase (quinone)\tK03923 mdaB; NADPH dehydrogenase (quinone) [EC:1.6.5.10]"
				},
				{
					"name":"Sph21_2625 FMN-dependent NADH-azoreductase\tK01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]"
				},
				{
					"name":"Sph21_4316 FMN-dependent NADH-azoreductase\tK01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]"
				},
				{
					"name":"Sph21_4746 FMN-dependent NADH-azoreductase\tK01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]"
				},
				{
					"name":"Sph21_4866 FMN-dependent NADH-azoreductase\tK01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]"
				},
				{
					"name":"Sph21_3181 FAD-dependent pyridine nucleotide-disulfide oxidoreductase\tK26960 bdr; bacillithiol disulfide reductase [EC:1.8.1.-]"
				},
				{
					"name":"Sph21_1064 Peptide methionine sulfoxide reductase msrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]"
				},
				{
					"name":"Sph21_1655 Peptide methionine sulfoxide reductase msrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]"
				},
				{
					"name":"Sph21_2419 methionine-R-sulfoxide reductase\tK07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]"
				},
				{
					"name":"Sph21_5042 Cytochrome-c peroxidase\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]"
				},
				{
					"name":"Sph21_2189 Catalase\tK07217 ydbD; manganese catalase [EC:1.11.1.6]"
				},
				{
					"name":"Sph21_4992 Chloride peroxidase\tK00433 cpo; non-heme chloroperoxidase [EC:1.11.1.10]"
				},
				{
					"name":"Sph21_5248 Chloride peroxidase\tK00433 cpo; non-heme chloroperoxidase [EC:1.11.1.10]"
				},
				{
					"name":"Sph21_3914 Peroxiredoxin\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"Sph21_4522 thiol peroxidase\tK11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"Sph21_3871 Peroxidase\tK24158 prx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"Sph21_0383 peroxiredoxin, OsmC subfamily\tK04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28]"
				},
				{
					"name":"Sph21_1843 peroxiredoxin, OsmC subfamily\tK04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28]"
				},
				{
					"name":"Sph21_4065 peroxiredoxin, OsmC subfamily\tK04063 osmC; lipoyl-dependent peroxiredoxin [EC:1.11.1.28]"
				},
				{
					"name":"Sph21_0298 Pirin domain protein\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]"
				},
				{
					"name":"Sph21_2612 Pirin domain protein\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]"
				},
				{
					"name":"Sph21_2512 Nitric oxide dioxygenase\tK05916 hmp; nitric oxide dioxygenase [EC:1.14.12.17]"
				},
				{
					"name":"Sph21_3029 fatty acid hydroxylase\tK19703 FA2H; 4-hydroxysphinganine ceramide fatty acyl 2-hydroxylase [EC:1.14.18.6]"
				},
				{
					"name":"Sph21_4486 fatty acid desaturase\tK23054 desC; sn-1 stearoyl-lipid 9-desaturase [EC:1.14.19.28]"
				},
				{
					"name":"Sph21_2220 Ferritin Dps family protein\tK02217 ftnA; ferritin [EC:1.16.3.2]"
				},
				{
					"name":"Sph21_0232 protein tyrosine phosphatase\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]"
				},
				{
					"name":"Sph21_4779 protein tyrosine phosphatase\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]"
				},
				{
					"name":"Sph21_4351 short-chain dehydrogenase\/reductase SDR\tK14189 dltE; uncharacterized oxidoreductase [EC:1.-.-.-]"
				},
				{
					"name":"Sph21_0320 Protein-L-isoaspartate O-methyltransferase\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]"
				},
				{
					"name":"Sph21_1489 Protein-L-isoaspartate O-methyltransferase\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]"
				},
				{
					"name":"Sph21_3687 Cyclopropane-fatty-acyl-phospholipid synthase\tK00574 cfa; cyclopropane-fatty-acyl-phospholipid synthase [EC:2.1.1.79]"
				},
				{
					"name":"Sph21_4519 Trans-aconitate 2-methyltransferase\tK00598 tam; trans-aconitate 2-methyltransferase [EC:2.1.1.144]"
				},
				{
					"name":"Sph21_1038 N-acetylornithine carbamoyltransferase\tK13043 argF; N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11]"
				},
				{
					"name":"Sph21_3825 Carbamoyltransferase\tK00612 nodU; carbamoyltransferase [EC:2.1.3.-]"
				},
				{
					"name":"Sph21_4751 GCN5-related N-acetyltransferase\tK22441 paiA; diamine N-acetyltransferase [EC:2.3.1.57]"
				},
				{
					"name":"Sph21_4060 Arylamine N-acetyltransferase\tK00675 nhoA; N-hydroxyarylamine O-acetyltransferase [EC:2.3.1.118]"
				},
				{
					"name":"Sph21_5223 Apolipoprotein N-acyltransferase\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]"
				},
				{
					"name":"Sph21_3395 GCN5-related N-acetyltransferase\tK03826 yiaB_C; [protein]-L-lysine N-acetyltransferase [EC:2.3.1.338]"
				},
				{
					"name":"Sph21_0544 GCN5-related N-acetyltransferase\tK03828 yjgM; putative acetyltransferase [EC:2.3.1.-]"
				},
				{
					"name":"Sph21_0668 glutamine cyclotransferase\tK22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]"
				},
				{
					"name":"Sph21_1161 leucyl\/phenylalanyl-tRNA\/protein transferase\tK00684 aat; leucyl\/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]"
				},
				{
					"name":"Sph21_2601 HAD-superfamily hydrolase, subfamily IIB\tK03692 E2.4.1.213; glucosylglycerol-phosphate synthase [EC:2.4.1.213]"
				},
				{
					"name":"Sph21_0930 glycosidase related protein\tK16212 mgp; 4-O-beta-D-mannosyl-D-glucose phosphorylase [EC:2.4.1.281]"
				},
				{
					"name":"Sph21_1613 glycosyl transferase group 1\tK00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"Sph21_1547 deoxyhypusine synthase\tK00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]"
				},
				{
					"name":"Sph21_3095 Prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]"
				},
				{
					"name":"Sph21_3624 prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]"
				},
				{
					"name":"Sph21_3453 ApbE family lipoprotein\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]"
				},
				{
					"name":"Sph21_0980 hypothetical protein\tK22129 dtnK; D-threonate\/D-erythronate kinase [EC:2.7.1.219 2.7.1.220]"
				},
				{
					"name":"Sph21_2162 type III effector Hrp-dependent outer domain protein\tK23247 oiaK; 3-oxoisoapionate kinase [EC:2.7.1.231]"
				},
				{
					"name":"Sph21_3225 RNA-directed DNA polymerase (Reverse transcriptase)\tK00986 ltrA; RNA-directed DNA polymerase [EC:2.7.7.49]"
				},
				{
					"name":"Sph21_1233 Conserved hypothetical protein CHP00159\tK18672 dacA; diadenylate cyclase [EC:2.7.7.85]"
				},
				{
					"name":"Sph21_2340 Formyl-CoA transferase\tK18702 uctC; CoA:oxalate CoA-transferase [EC:2.8.3.19]"
				},
				{
					"name":"Sph21_2348 Sialate O-acetylesterase\tK05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53]"
				},
				{
					"name":"Sph21_2657 protein of unknown function DUF303 acetylesterase\tK05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53]"
				},
				{
					"name":"Sph21_4286 Sialate O-acetylesterase\tK05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53]"
				},
				{
					"name":"Sph21_0469 lipolytic protein G-D-S-L family\tK15530 RGAE; rhamnogalacturonan acetylesterase [EC:3.1.1.86]"
				},
				{
					"name":"Sph21_5022 Appr-1-p processing domain protein\tK23518 MACROD; O-acetyl-ADP-ribose deacetylase [EC:3.1.1.106]"
				},
				{
					"name":"Sph21_0445 glycoside hydrolase family 2 sugar binding protein\tK25010 GE; (4-O-methyl)-D-glucuronate---lignin esterase [EC:3.1.1.117]"
				},
				{
					"name":"Sph21_2346 glycoside hydrolase family 2 sugar binding protein\tK25010 GE; (4-O-methyl)-D-glucuronate---lignin esterase [EC:3.1.1.117]"
				},
				{
					"name":"Sph21_0122 Carboxylesterase\tK03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-]"
				},
				{
					"name":"Sph21_0202 Carboxylesterase type B\tK03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-]"
				},
				{
					"name":"Sph21_4324 Carboxylesterase type B\tK03929 pnbA; para-nitrobenzyl esterase [EC:3.1.1.-]"
				},
				{
					"name":"Sph21_0003 thioesterase superfamily protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"Sph21_3071 4-hydroxybenzoyl-CoA thioesterase\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"Sph21_4549 thioesterase-like protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"Sph21_4856 hypothetical protein\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"Sph21_1835 capsular polysaccharide biosynthesis protein\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"Sph21_2000 capsular polysaccharide biosynthesis protein\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"Sph21_4026 putative phosphohistidine phosphatase, SixA\tK08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]"
				},
				{
					"name":"Sph21_2478 7TM receptor with intracellular metal dependent phosphohydrolase\tK07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]"
				},
				{
					"name":"Sph21_1244 hydrolase, TatD family\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"Sph21_3658 TatD-related deoxyribonuclease\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"Sph21_0594 glycoside hydrolase family 43\tK06113 abnA; arabinan endo-1,5-alpha-L-arabinosidase [EC:3.2.1.99]"
				},
				{
					"name":"Sph21_1452 Mannosylglycoprotein endo-beta-mannosidase\tK18577 EBM; mannosylglycoprotein endo-beta-mannosidase [EC:3.2.1.152]"
				},
				{
					"name":"Sph21_0495 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Sph21_0796 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Sph21_0942 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Sph21_2891 glycosyl hydrolase family 88\tK15532 yteR; unsaturated rhamnogalacturonyl hydrolase [EC:3.2.1.172]"
				},
				{
					"name":"Sph21_3924 glycoside hydrolase family 31\tK01811 xylS; alpha-D-xyloside xylohydrolase [EC:3.2.1.177]"
				},
				{
					"name":"Sph21_0725 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_0730 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_2781 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_2869 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_4419 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_4699 glycosyl hydrolase family 88\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"Sph21_0797 glycoside hydrolase family 16\tK20832 EN3GAL; galactan endo-beta-1,3-galactanase [EC:3.2.1.181]"
				},
				{
					"name":"Sph21_4796 glycosidase related protein\tK21065 E3.2.1.197; beta-1,2-mannosidase [EC:3.2.1.197]"
				},
				{
					"name":"Sph21_0614 hypothetical protein\tK27494 exoMA1; D-arabinan exo alpha-(1,3)\/(1,5)-arabinofuranosidase (non-reducing end) [EC:3.2.1.225]"
				},
				{
					"name":"Sph21_1163 Peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"Sph21_1256 Peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"Sph21_4139 polysaccharide deacetylase\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]"
				},
				{
					"name":"Sph21_2998 LmbE family protein\tK01463 bshB1; N-acetylglucosamine malate deacetylase 1 [EC:3.5.1.-]"
				},
				{
					"name":"Sph21_0834 Endoribonuclease L-PSP\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"Sph21_1157 endoribonuclease L-PSP\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"Sph21_2959 Endoribonuclease L-PSP\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"Sph21_2107 nucleoside diphosphate pyrophosphatase\tK12945 nudK; GDP-mannose pyrophosphatase NudK [EC:3.6.1.-]"
				},
				{
					"name":"Sph21_0712 ATPase associated with various cellular activities AAA_3\tK03924 moxR; MoxR-like ATPase [EC:3.6.3.-]"
				},
				{
					"name":"Sph21_2161 Ribulose-bisphosphate carboxylase\tK01559 oiaT; 3-oxoisoapionate-4-phosphate transcarboxylase\/hydrolase [EC:3.7.1.28]"
				},
				{
					"name":"Sph21_5264 YjeF-related protein\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]"
				},
				{
					"name":"Sph21_0932 N-acylglucosamine 2-epimerase\tK16213 cbe; cellobiose epimerase [EC:5.1.3.11]"
				},
				{
					"name":"Sph21_0467 L-rhamnose 1-epimerase\tK03534 rhaM; L-rhamnose mutarotase [EC:5.1.3.32]"
				},
				{
					"name":"Sph21_3047 UDP-N-acetylmuramate--L-alanine ligase\tK02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45]"
				},
				{
					"name":"Sph21_0281 copper-translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]"
				},
				{
					"name":"Sph21_0283 heavy metal translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]"
				},
				{
					"name":"Sph21_4251 copper-translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]"
				},
				{
					"name":"Sph21_0227 heavy metal translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				},
				{
					"name":"Sph21_3663 heavy metal translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				}
				]
			},
			{
				"name":"99981 Carbohydrate metabolism",
				"children":[
				{
					"name":"Sph21_0660 protein of unknown function DUF224 cysteine-rich region domain protein\tK18928 lldE; L-lactate dehydrogenase complex protein LldE"
				},
				{
					"name":"Sph21_2943 protein of unknown function DUF224 cysteine-rich region domain protein\tK18928 lldE; L-lactate dehydrogenase complex protein LldE"
				},
				{
					"name":"Sph21_0017 Lactate utilization protein B\/C\tK18929 lldF; L-lactate dehydrogenase complex protein LldF"
				},
				{
					"name":"Sph21_0659 Lactate utilization protein B\/C\tK18929 lldF; L-lactate dehydrogenase complex protein LldF"
				},
				{
					"name":"Sph21_0658 Lactate utilization protein B\/C\tK00782 lldG; L-lactate dehydrogenase complex protein LldG"
				},
				{
					"name":"Sph21_1056 Lactate utilization protein B\/C\tK00782 lldG; L-lactate dehydrogenase complex protein LldG"
				},
				{
					"name":"Sph21_5187 UPF0747 protein\tK22136 bshC; bacillithiol synthase"
				},
				{
					"name":"Sph21_3640 twin-arginine translocation pathway signal\tK26060 gtd2; glucoside 3-dehydrogenase (cytochrome c) hitch-hiker subunit"
				}
				]
			},
			{
				"name":"99982 Energy metabolism",
				"children":[
				{
					"name":"Sph21_1065 NADPH:quinone reductase\tK13955 yogA; zinc-binding alcohol dehydrogenase\/oxidoreductase"
				},
				{
					"name":"Sph21_3061 Electron transfer flavoprotein alpha\/beta-subunit\tK03521 fixA; electron transfer flavoprotein beta subunit"
				},
				{
					"name":"Sph21_3248 protein of unknown function DUF1458\tK09165 K09165; dodecin"
				}
				]
			},
			{
				"name":"99983 Lipid metabolism"
			},
			{
				"name":"99984 Nucleotide metabolism",
				"children":[
				{
					"name":"Sph21_2912 NrdI protein\tK03647 nrdI; protein involved in ribonucleotide reduction"
				}
				]
			},
			{
				"name":"99985 Amino acid metabolism",
				"children":[
				{
					"name":"Sph21_0779 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK08234 yaeR; glyoxylase I family protein"
				},
				{
					"name":"Sph21_4672 protein of unknown function UPF0001\tK06997 yggS; PLP dependent protein"
				}
				]
			},
			{
				"name":"99986 Glycan metabolism",
				"children":[
				{
					"name":"Sph21_5161 hypothetical protein\tK07027 K07027; glycosyltransferase 2 family protein"
				}
				]
			},
			{
				"name":"99987 Cofactor metabolism"
			},
			{
				"name":"99988 Secondary metabolism",
				"children":[
				{
					"name":"Sph21_0877 phospholipase\/Carboxylesterase\tK03932 lpqC; polyhydroxybutyrate depolymerase"
				},
				{
					"name":"Sph21_0429 NADPH-dependent FMN reductase\tK19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)"
				}
				]
			},
			{
				"name":"99999 Others",
				"children":[
				{
					"name":"Sph21_0645 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK15975 K15975; glyoxalase family protein"
				},
				{
					"name":"Sph21_1425 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"Sph21_3128 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"Sph21_4126 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"Sph21_4183 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"Sph21_5093 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"Sph21_0644 phospholipase\/Carboxylesterase\tK06999 K06999; phospholipase\/carboxylesterase"
				},
				{
					"name":"Sph21_1234 protein of unknown function DUF1094\tK26958 brxA_B; bacilliredoxin"
				},
				{
					"name":"Sph21_5261 hypothetical protein\tK26959 brxC; monothiol bacilliredoxin"
				}
				]
			}
			]
		},
		{
			"name":"09192 Unclassified: genetic information processing",
			"children":[
			{
				"name":"99973 Transcription",
				"children":[
				{
					"name":"Sph21_0773 cold-shock DNA-binding domain protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"Sph21_2125 cold-shock DNA-binding domain protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"Sph21_3870 cold-shock DNA-binding domain protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"Sph21_4482 Cold-shock protein DNA-binding protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"Sph21_4687 cold-shock DNA-binding domain protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"Sph21_2541 Tex-like protein\tK06959 tex; protein Tex"
				}
				]
			},
			{
				"name":"99974 Translation",
				"children":[
				{
					"name":"Sph21_2526 beta-lactamase domain protein\tK07576 K07576; metallo-beta-lactamase family protein"
				},
				{
					"name":"Sph21_1107 RNA procession exonuclease\tK07577 K07577; putative mRNA 3-end processing factor"
				},
				{
					"name":"Sph21_4002 RNA procession exonuclease-like protein\tK07577 K07577; putative mRNA 3-end processing factor"
				}
				]
			},
			{
				"name":"99975 Protein processing",
				"children":[
				{
					"name":"Sph21_2457 protein of unknown function DUF306 Meta and HslJ\tK03668 hslJ; heat shock protein HslJ"
				},
				{
					"name":"Sph21_1502 ATP-dependent Clp protease adaptor protein ClpS\tK06891 clpS; ATP-dependent Clp protease adaptor protein ClpS"
				},
				{
					"name":"Sph21_2924 trigger factor\tK03545 tig; trigger factor"
				},
				{
					"name":"Sph21_0319 SsrA-binding protein\tK03664 smpB; SsrA-binding protein"
				},
				{
					"name":"Sph21_1443 Mg chelatase, subunit ChlI\tK07391 comM; magnesium chelatase family protein"
				},
				{
					"name":"Sph21_0554 OsmC family protein\tK07397 yhfA; putative redox protein"
				},
				{
					"name":"Sph21_3442 OsmC family protein\tK07397 yhfA; putative redox protein"
				},
				{
					"name":"Sph21_3328 selT\/selW\/selH selenoprotein domain-containing protein\tK07401 K07401; selenoprotein W-related protein"
				},
				{
					"name":"Sph21_0137 Xanthine dehydrogenase\tK07402 xdhC; xanthine dehydrogenase accessory factor"
				},
				{
					"name":"Sph21_3740 Xanthine dehydrogenase\tK07402 xdhC; xanthine dehydrogenase accessory factor"
				},
				{
					"name":"Sph21_4662 protein of unknown function DUF107\tK07403 nfeD; membrane-bound serine protease (ClpP class)"
				}
				]
			},
			{
				"name":"99976 Replication and repair",
				"children":[
				{
					"name":"Sph21_1496 Methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein\tK07443 ybaZ; methylated-DNA-protein-cysteine methyltransferase related protein"
				},
				{
					"name":"Sph21_3957 DNA repair protein RadC\tK03630 radC; DNA repair protein RadC"
				},
				{
					"name":"Sph21_1294 RmuC-domain protein\tK09760 rmuC; DNA recombination protein RmuC"
				},
				{
					"name":"Sph21_0669 UPF0102 protein yraN\tK07460 yraN; putative endonuclease"
				},
				{
					"name":"Sph21_1482 Excinuclease ABC C subunit domain protein\tK07461 K07461; putative endonuclease"
				},
				{
					"name":"Sph21_1864 Excinuclease ABC C subunit domain protein\tK07461 K07461; putative endonuclease"
				},
				{
					"name":"Sph21_3113 hypothetical protein\tK07461 K07461; putative endonuclease"
				},
				{
					"name":"Sph21_2524 DNA protecting protein DprA\tK04096 smf; DNA processing protein"
				},
				{
					"name":"Sph21_1359 AAA ATPase central domain protein\tK07478 ycaJ; putative ATPase"
				},
				{
					"name":"Sph21_0164 transposase IS66\tK07484 K07484; transposase"
				},
				{
					"name":"Sph21_4929 IS66 Orf2 family protein\tK07484 K07484; transposase"
				},
				{
					"name":"Sph21_4930 transposase IS66\tK07484 K07484; transposase"
				},
				{
					"name":"Sph21_5071 IS66 Orf2 family protein\tK07484 K07484; transposase"
				},
				{
					"name":"Sph21_5072 transposase IS66\tK07484 K07484; transposase"
				},
				{
					"name":"Sph21_0033 transposase IS204\/IS1001\/IS1096\/IS1165 family protein\tK07485 K07485; transposase"
				},
				{
					"name":"Sph21_0113 transposase IS204\/IS1001\/IS1096\/IS1165 family protein\tK07485 K07485; transposase"
				},
				{
					"name":"Sph21_0311 transposase IS204\/IS1001\/IS1096\/IS1165 family protein\tK07485 K07485; transposase"
				},
				{
					"name":"Sph21_0365 transposase IS204\/IS1001\/IS1096\/IS1165 family protein\tK07485 K07485; transposase"
				},
				{
					"name":"Sph21_0414 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_0637 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_1469 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_1651 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_2336 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_2897 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_3272 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				},
				{
					"name":"Sph21_4984 transposase IS116\/IS110\/IS902 family protein\tK07486 K07486; transposase"
				}
				]
			},
			{
				"name":"99979 Viral proteins"
			},
			{
				"name":"99998 Others",
				"children":[
				{
					"name":"Sph21_1521 Uncharacterized protein family UPF0133\tK09747 ebfC; nucleoid-associated protein EbfC"
				},
				{
					"name":"Sph21_1683 cryptochrome, DASH family\tK25656 cry; cryptochrome"
				}
				]
			}
			]
		},
		{
			"name":"09193 Unclassified: signaling and cellular processes",
			"children":[
			{
				"name":"99977 Transport",
				"children":[
				{
					"name":"Sph21_0931 sugar (Glycoside-Pentoside-Hexuronide) transporter\tK03292 TC.GPH; glycoside\/pentoside\/hexuronide:cation symporter, GPH family"
				},
				{
					"name":"Sph21_1019 amino acid permease-associated region\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"Sph21_2244 amino acid permease-associated region\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"Sph21_2247 amino acid permease-associated region\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"Sph21_3706 amino acid permease-associated region\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"Sph21_3909 amino acid permease-associated region\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"Sph21_1012 amino acid\/peptide transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family"
				},
				{
					"name":"Sph21_2472 amino acid\/peptide transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family"
				},
				{
					"name":"Sph21_1371 phosphate transporter\tK03306 TC.PIT; inorganic phosphate transporter, PiT family"
				},
				{
					"name":"Sph21_0197 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_0979 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_1032 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_1347 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_2299 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_2335 SSS sodium solute transporter superfamily\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_4265 Na+\/solute symporter\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"Sph21_0204 amino acid carrier protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family"
				},
				{
					"name":"Sph21_2164 Bile acid:sodium symporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family"
				},
				{
					"name":"Sph21_2638 Bile acid:sodium symporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family"
				},
				{
					"name":"Sph21_2961 Bile acid:sodium symporter\tK03453 TC.BASS; bile acid:Na+ symporter, BASS family"
				}
				]
			},
			{
				"name":"99978 Cell growth",
				"children":[
				{
					"name":"Sph21_2711 urea amidolyase related protein\tK06350 kipA; antagonist of KipI"
				},
				{
					"name":"Sph21_2712 Conserved hypothetical protein CHP00370\tK06351 kipI; inhibitor of KinA"
				},
				{
					"name":"Sph21_1144 Peptidase M23\tK22719 envC; murein hydrolase activator"
				}
				]
			},
			{
				"name":"99993 Cell motility",
				"children":[
				{
					"name":"Sph21_3647 hypothetical protein\tK07337 K07337; penicillin-binding protein activator"
				}
				]
			},
			{
				"name":"99995 Signaling proteins",
				"children":[
				{
					"name":"Sph21_1630 GTP-binding protein TypA\tK06207 typA; GTP-binding protein"
				},
				{
					"name":"Sph21_2530 PhoH family protein\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins"
				},
				{
					"name":"Sph21_5126 putative signal transduction protein with CBS domains\tK07182 K07182; CBS domain-containing protein"
				}
				]
			},
			{
				"name":"99992 Structural proteins",
				"children":[
				{
					"name":"Sph21_2459 outer membrane chaperone Skp (OmpH)\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"Sph21_5199 outer membrane chaperone Skp (OmpH)\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"Sph21_5200 outer membrane chaperone Skp (OmpH)\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"Sph21_1173 efflux transporter, RND family, MFP subunit\tK02005 ABC.CD.TX; HlyD family secretion protein"
				},
				{
					"name":"Sph21_3415 efflux transporter, RND family, MFP subunit\tK02005 ABC.CD.TX; HlyD family secretion protein"
				},
				{
					"name":"Sph21_4137 efflux transporter, RND family, MFP subunit\tK02005 ABC.CD.TX; HlyD family secretion protein"
				},
				{
					"name":"Sph21_2483 Inner membrane CreD family protein\tK06143 creD; inner membrane protein"
				}
				]
			},
			{
				"name":"99994 Others",
				"children":[
				{
					"name":"Sph21_3891 Copper homeostasis protein cutC\tK06201 cutC; copper homeostasis protein"
				},
				{
					"name":"Sph21_1302 ApaG domain protein\tK06195 apaG; ApaG protein"
				},
				{
					"name":"Sph21_0230 Flavin-containing monooxygenase-like protein\tK07222 K07222; putative flavoprotein involved in K+ transport"
				},
				{
					"name":"Sph21_4956 hypothetical protein\tK26994 sdpA; sporulation delaying protein A"
				},
				{
					"name":"Sph21_4958 HTTM domain protein\tK26995 sdpB; sporulation delaying protein B"
				}
				]
			}
			]
		},
		{
			"name":"09194 Poorly characterized",
			"children":[
			{
				"name":"99996 General function prediction only",
				"children":[
				{
					"name":"Sph21_1206 GCN5-related N-acetyltransferase\tK02348 elaA; ElaA protein"
				},
				{
					"name":"Sph21_1068 export-related chaperone CsaA\tK06878 K06878; tRNA-binding protein"
				},
				{
					"name":"Sph21_1394 hypothetical protein\tK06886 glbN; hemoglobin"
				},
				{
					"name":"Sph21_4097 Patatin\tK07001 K07001; NTE family protein"
				},
				{
					"name":"Sph21_0723 HAD superfamily (subfamily IA) hydrolase, TIGR02254\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"Sph21_2193 HAD-superfamily hydrolase, subfamily IA, variant 3\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"Sph21_4017 FeS assembly protein SufB\tK09014 sufB; Fe-S cluster assembly protein SufB"
				},
				{
					"name":"Sph21_4015 FeS assembly protein SufD\tK09015 sufD; Fe-S cluster assembly protein SufD"
				},
				{
					"name":"Sph21_1535 ribonuclease BN\tK07058 K07058; membrane protein"
				},
				{
					"name":"Sph21_2110 ribonuclease BN\tK07058 K07058; membrane protein"
				},
				{
					"name":"Sph21_3070 ribonuclease BN\tK07058 K07058; membrane protein"
				},
				{
					"name":"Sph21_4013 Fe-S metabolism associated SufE\tK02426 sufE; cysteine desulfuration protein SufE"
				},
				{
					"name":"Sph21_1417 UPF0176 protein yceA\tK07146 K07146; UPF0176 protein"
				},
				{
					"name":"Sph21_4503 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK04750 phnB; PhnB protein"
				},
				{
					"name":"Sph21_0734 LemA family protein\tK03744 lemA; LemA protein"
				},
				{
					"name":"Sph21_1601 SNARE associated Golgi protein-related protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"Sph21_1713 SNARE associated Golgi protein-related protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"Sph21_2758 SNARE associated Golgi protein-related protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"Sph21_4491 SNARE associated Golgi protein-related protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"Sph21_1611 membrane protein of unknown function\tK08972 K08972; putative membrane protein"
				},
				{
					"name":"Sph21_1562 protein of unknown function DUF420\tK08976 K08976; putative membrane protein"
				},
				{
					"name":"Sph21_2101 outer membrane protein-like protein\tK08995 K08995; putative membrane protein"
				},
				{
					"name":"Sph21_2184 putative outer membrane protein\tK08995 K08995; putative membrane protein"
				},
				{
					"name":"Sph21_3834 hypothetical protein\tK08995 K08995; putative membrane protein"
				},
				{
					"name":"Sph21_1219 PhnA protein\tK06193 phnA; protein PhnA"
				},
				{
					"name":"Sph21_4752 protein of unknown function DUF417\tK21741 rclC; reactive chlorine resistance protein C"
				}
				]
			},
			{
				"name":"99997 Function unknown",
				"children":[
				{
					"name":"Sph21_1924 ankyrin\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"Sph21_2448 Ankyrin\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"Sph21_2545 Ankyrin\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"Sph21_5076 Ankyrin\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"Sph21_0688 Radical SAM domain protein\tK06871 K06871; uncharacterized protein"
				},
				{
					"name":"Sph21_0736 protein of unknown function DUF477\tK06872 K06872; uncharacterized protein"
				},
				{
					"name":"Sph21_1539 metal dependent phosphohydrolase\tK06885 K06885; uncharacterized protein"
				},
				{
					"name":"Sph21_3339 metal dependent phosphohydrolase\tK06885 K06885; uncharacterized protein"
				},
				{
					"name":"Sph21_3542 protein of unknown function DUF255\tK06888 K06888; uncharacterized protein"
				},
				{
					"name":"Sph21_0120 hypothetical protein\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"Sph21_2461 hypothetical protein\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"Sph21_2784 alpha\/beta superfamily hydrolase\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"Sph21_4361 hypothetical protein\tK06893 K06893; uncharacterized protein"
				},
				{
					"name":"Sph21_4400 hypothetical protein\tK06893 K06893; uncharacterized protein"
				},
				{
					"name":"Sph21_4563 hypothetical protein\tK06893 K06893; uncharacterized protein"
				},
				{
					"name":"Sph21_2662 protein of unknown function DUF296\tK06934 K06934; uncharacterized protein"
				},
				{
					"name":"Sph21_1329 metal dependent phosphohydrolase\tK06950 K06950; uncharacterized protein"
				},
				{
					"name":"Sph21_1110 metallophosphoesterase\tK06953 K06953; uncharacterized protein"
				},
				{
					"name":"Sph21_1293 peptidase membrane zinc metallopeptidase\tK06973 K06973; uncharacterized protein"
				},
				{
					"name":"Sph21_2611 GCN5-related N-acetyltransferase\tK06975 K06975; uncharacterized protein"
				},
				{
					"name":"Sph21_2698 acetyltransferase\tK06975 K06975; uncharacterized protein"
				},
				{
					"name":"Sph21_2808 hydrolase CocE\/NonD family protein\tK06978 K06978; uncharacterized protein"
				},
				{
					"name":"Sph21_4724 Succinylglutamate desuccinylase\/aspartoacylase\tK06987 K06987; uncharacterized protein"
				},
				{
					"name":"Sph21_2108 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK06996 K06996; uncharacterized protein"
				},
				{
					"name":"Sph21_4502 glyoxalase\/bleomycin resistance protein\/dioxygenase\tK06996 K06996; uncharacterized protein"
				},
				{
					"name":"Sph21_2115 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein\tK07005 K07005; uncharacterized protein"
				},
				{
					"name":"Sph21_2720 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein\tK07006 K07006; uncharacterized protein"
				},
				{
					"name":"Sph21_2921 Glyoxalase\/bleomycin resistance protein\/dioxygenase\tK07032 K07032; uncharacterized protein"
				},
				{
					"name":"Sph21_0450 TatD-related deoxyribonuclease\tK07051 K07051; uncharacterized protein"
				},
				{
					"name":"Sph21_2233 protein of unknown function zinc metallopeptidase\tK07054 K07054; uncharacterized protein"
				},
				{
					"name":"Sph21_1873 protein of unknown function DUF132\tK07063 K07063; uncharacterized protein"
				},
				{
					"name":"Sph21_4392 protein of unknown function DUF132\tK07063 K07063; uncharacterized protein"
				},
				{
					"name":"Sph21_1681 domain of unknown function DUF1731\tK07071 K07071; uncharacterized protein"
				},
				{
					"name":"Sph21_1208 DNA polymerase beta domain protein region\tK07075 K07075; uncharacterized protein"
				},
				{
					"name":"Sph21_0140 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Sph21_3192 siroheme synthase\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Sph21_3586 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Sph21_3736 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Sph21_3867 protein of unknown function DUF81\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"Sph21_3142 phosphodiesterase, MJ0936 family\tK07095 K07095; uncharacterized protein"
				},
				{
					"name":"Sph21_0177 metallophosphoesterase\tK07098 K07098; uncharacterized protein"
				},
				{
					"name":"Sph21_1070 metallophosphoesterase\tK07098 K07098; uncharacterized protein"
				},
				{
					"name":"Sph21_3593 protein of unknown function DUF395 YeeE\/YedE\tK07112 K07112; uncharacterized protein"
				},
				{
					"name":"Sph21_3594 protein of unknown function DUF395 YeeE\/YedE\tK07112 K07112; uncharacterized protein"
				},
				{
					"name":"Sph21_0188 NAD-dependent epimerase\/dehydratase\tK07118 K07118; uncharacterized protein"
				},
				{
					"name":"Sph21_2177 Estradiol 17-beta-dehydrogenase\tK07124 K07124; uncharacterized protein"
				},
				{
					"name":"Sph21_2409 short-chain dehydrogenase\/reductase SDR\tK07124 K07124; uncharacterized protein"
				},
				{
					"name":"Sph21_2811 Sel1 domain protein repeat-containing protein\tK07126 K07126; uncharacterized protein"
				},
				{
					"name":"Sph21_0400 hypothetical protein\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_0827 hypothetical protein\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_0845 AAA family ATPase\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_0848 AAA ATPase\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_4403 hypothetical protein\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_4408 hypothetical protein\tK07133 K07133; uncharacterized protein"
				},
				{
					"name":"Sph21_0733 HI0933 family protein\tK07137 K07137; uncharacterized protein"
				},
				{
					"name":"Sph21_4109 Conserved hypothetical protein CHP01212\tK07139 K07139; uncharacterized protein"
				},
				{
					"name":"Sph21_2154 MOSC domain containing protein\tK07140 K07140; MOSC domain-containing protein"
				},
				{
					"name":"Sph21_0147 protein of unknown function DUF418\tK07148 K07148; uncharacterized protein"
				},
				{
					"name":"Sph21_0274 protein of unknown function DUF418\tK07148 K07148; uncharacterized protein"
				},
				{
					"name":"Sph21_1999 protein of unknown function DUF418\tK07148 K07148; uncharacterized protein"
				},
				{
					"name":"Sph21_1377 protein of unknown function DUF164\tK07164 K07164; uncharacterized protein"
				},
				{
					"name":"Sph21_0326 UPF0161 protein yidD\tK08998 K08998; uncharacterized protein"
				},
				{
					"name":"Sph21_3059 protein of unknown function DUF151\tK08999 K08999; uncharacterized protein"
				},
				{
					"name":"Sph21_4106 protein of unknown function DUF763\tK09003 K09003; uncharacterized protein"
				},
				{
					"name":"Sph21_2151 hypothetical protein\tK09004 K09004; uncharacterized protein"
				},
				{
					"name":"Sph21_5207 GatB\/YqeY domain-containing protein\tK09117 K09117; uncharacterized protein"
				},
				{
					"name":"Sph21_3352 protein of unknown function DUF190\tK09137 K09137; uncharacterized protein"
				},
				{
					"name":"Sph21_3334 protein of unknown function DUF1684\tK09164 K09164; uncharacterized protein"
				},
				{
					"name":"Sph21_4703 protein of unknown function DUF1349\tK09702 K09702; uncharacterized protein"
				},
				{
					"name":"Sph21_2819 Uncharacterized conserved protein UCP028846\tK09704 K09704; uncharacterized protein"
				},
				{
					"name":"Sph21_0413 protein of unknown function DUF458, RNase H-like protein\tK09776 K09776; uncharacterized protein"
				},
				{
					"name":"Sph21_0217 protein of unknown function DUF808\tK09781 K09781; uncharacterized protein"
				},
				{
					"name":"Sph21_3532 integral membrane protein\tK09792 K09792; uncharacterized protein"
				},
				{
					"name":"Sph21_0044 protein of unknown function DUF541\tK09807 K09807; uncharacterized protein"
				},
				{
					"name":"Sph21_3326 RNA binding S1 domain protein\tK00243 K00243; uncharacterized protein"
				},
				{
					"name":"Sph21_3646 hypothetical protein\tK09859 K09859; uncharacterized protein"
				},
				{
					"name":"Sph21_2203 UPF0502 protein yceH\tK09915 K09915; uncharacterized protein"
				},
				{
					"name":"Sph21_4267 protein of unknown function DUF486\tK09922 K09922; uncharacterized protein"
				},
				{
					"name":"Sph21_4328 hypothetical protein\tK09932 K09932; uncharacterized protein"
				},
				{
					"name":"Sph21_3668 protein of unknown function DUF1508\tK09946 K09946; uncharacterized protein"
				},
				{
					"name":"Sph21_1344 hypothetical protein\tK09954 K09954; uncharacterized protein"
				},
				{
					"name":"Sph21_0921 protein of unknown function DUF1680\tK09955 K09955; uncharacterized protein"
				},
				{
					"name":"Sph21_2347 protein of unknown function DUF1680\tK09955 K09955; uncharacterized protein"
				},
				{
					"name":"Sph21_4284 protein of unknown function DUF1680\tK09955 K09955; uncharacterized protein"
				},
				{
					"name":"Sph21_4710 protein of unknown function DUF1680\tK09955 K09955; uncharacterized protein"
				},
				{
					"name":"Sph21_4347 protein of unknown function DUF1348\tK09958 K09958; uncharacterized protein"
				},
				{
					"name":"Sph21_1454 GumN family protein\tK09973 K09973; uncharacterized protein"
				},
				{
					"name":"Sph21_2563 hypothetical protein\tK09981 K09981; uncharacterized protein"
				},
				{
					"name":"Sph21_5114 Protein of unknown function DUF2086\tK09990 K09990; uncharacterized protein"
				},
				{
					"name":"Sph21_0629 hypothetical protein\tK09992 K09992; uncharacterized protein"
				},
				{
					"name":"Sph21_2277 Crp\/FNR family transcriptional regulator\tK09992 K09992; uncharacterized protein"
				},
				{
					"name":"Sph21_1370 putative phosphate transport regulator\tK07220 K07220; uncharacterized protein"
				}
				]
			}
			]
		}
		]
	}
	]
}