{
	"name":"shx03029",
	"children":[
	{
		"name":"Mitochondrial DNA transcription, translation, and replication factors",
		"children":[
		{
			"name":"Mitochondrial DNA-encoded proteins",
			"children":[
			{
				"name":"Mitochondrial respiratory chain complex I",
				"children":[
				{
					"name":"4097440 ND1; NADH dehydrogenase subunit 1\tK03878 ND1; NADH-ubiquinone oxidoreductase chain 1 [EC:7.1.1.2]"
				},
				{
					"name":"4097436 ND2; NADH dehydrogenase subunit 2\tK03879 ND2; NADH-ubiquinone oxidoreductase chain 2 [EC:7.1.1.2]"
				},
				{
					"name":"4097439 ND3; NADH dehydrogenase subunit 3\tK03880 ND3; NADH-ubiquinone oxidoreductase chain 3 [EC:7.1.1.2]"
				},
				{
					"name":"4097446 ND4; NADH dehydrogenase subunit 4\tK03881 ND4; NADH-ubiquinone oxidoreductase chain 4 [EC:7.1.1.2]"
				},
				{
					"name":"4097437 ND5; NADH dehydrogenase subunit 5\tK03883 ND5; NADH-ubiquinone oxidoreductase chain 5 [EC:7.1.1.2]"
				},
				{
					"name":"4097443 ND6; NADH dehydrogenase subunit 6\tK03884 ND6; NADH-ubiquinone oxidoreductase chain 6 [EC:7.1.1.2]"
				}
				]
			},
			{
				"name":"Mitochondrial respiratory chain complex III",
				"children":[
				{
					"name":"4097445 CYTB; cytochrome b\tK00412 CYTB; ubiquinol-cytochrome c reductase cytochrome b subunit"
				}
				]
			},
			{
				"name":"Cytochrome c oxidase",
				"children":[
				{
					"name":"4097441 COX1; cytochrome c oxidase subunit I\tK02256 COX1; cytochrome c oxidase subunit 1 [EC:7.1.1.9]"
				},
				{
					"name":"4097442 COX2; cytochrome c oxidase subunit II\tK02261 COX2; cytochrome c oxidase subunit 2"
				}
				]
			},
			{
				"name":"F-type ATPase"
			}
			]
		},
		{
			"name":"Mitochondrial transcription and translation factors",
			"children":[
			{
				"name":"Mitochondrial RNA polymerase",
				"children":[
				{
					"name":"MS3_00001986 hypothetical protein\tK10908 POLRMT; DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6]"
				}
				]
			},
			{
				"name":"Mitochondrial transcription factors",
				"children":[
				{
					"name":"MS3_00008378 hypothetical protein\tK11830 TFAM; transcription factor A, mitochondrial"
				},
				{
					"name":"MS3_00020006 TFB1M_1; Dimethyladenosine transferase 1, mitochondrial\tK15266 TFB1M; dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-]"
				}
				]
			},
			{
				"name":"Mitochondrial translation factors",
				"children":[
				{
					"name":"MS3_00001390 MTIF2; Translation initiation factor IF-2, mitochondrial\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"MS3_00003196 TUF1; translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"MS3_00003493 GFM2_1; G elongation factor, mitochondrial 2\tK02355 fusA; elongation factor G"
				},
				{
					"name":"MS3_00004642 GFM1_1; elongation factor EF-G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"MS3_00003203 MTERF3; Transcription termination factor 3, mitochondrial\tK15031 MTERF; mitochondrial transcription termination factor family protein"
				}
				]
			},
			{
				"name":"RNase MRP",
				"children":[
				{
					"name":"MS3_00005617 POP1; Ribonucleases P\/MRP protein subunit pop1\tK01164 POP1; ribonuclease P\/MRP protein subunit POP1 [EC:3.1.26.5]"
				},
				{
					"name":"MS3_00007142 POP5; RNA-binding protein pop5\tK03537 POP5; ribonuclease P\/MRP protein subunit POP5 [EC:3.1.26.5]"
				},
				{
					"name":"MS3_00007855 RPP30; Ribonuclease P protein subunit p30\tK03539 RPP1; ribonuclease P\/MRP protein subunit RPP1 [EC:3.1.26.5]"
				},
				{
					"name":"MS3_00003797 hypothetical protein\tK14525 RPP25; ribonucleases P\/MRP protein subunit RPP25 [EC:3.1.26.5]"
				}
				]
			},
			{
				"name":"Mitochondrial ribonuclease P",
				"children":[
				{
					"name":"MS3_00003540 SUN1_1; Secreted beta-glucosidase sun1\tK17654 TRMT10C; mitochondrial ribonuclease P protein 1 [EC:2.1.1.-]"
				},
				{
					"name":"MS3_00007148 hypothetical protein\tK08683 HSD17B10; 3-hydroxyacyl-CoA dehydrogenase \/ 3-hydroxy-2-methylbutyryl-CoA dehydrogenase [EC:1.1.1.35 1.1.1.178]"
				},
				{
					"name":"MS3_00006787 hypothetical protein\tK17655 MRPP3; mitochondrial ribonuclease P protein 3"
				}
				]
			},
			{
				"name":"Other mitochondrial DNA transcription and translation factors",
				"children":[
				{
					"name":"MS3_00002377 NAA38; N(alpha)-acetyltransferase 38, NatC auxiliary, variant 2\tK17710 PTCD1; pentatricopeptide repeat domain-containing protein 1"
				},
				{
					"name":"MS3_00005414 UQCC1; Ubiquinol-cytochrome-c reductase complex assembly factor 1, variant 2\tK17662 CBP3; cytochrome b pre-mRNA-processing protein 3"
				},
				{
					"name":"MS3_00002809 PET9; ADP\/ATP carrier protein, variant 3\tK05863 SLC25A4S; solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4\/5\/6\/31"
				},
				{
					"name":"MS3_00007320 hypothetical protein\tK15113 SLC25A28_37; solute carrier family 25 (mitochondrial iron transporter), member 28\/37"
				},
				{
					"name":"MS3_00006390 YARS2_1; Tyrosine--tRNA ligase, mitochondrial\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"MS3_00009041 YARS1_1; Tyrosine--tRNA ligase, cytoplasmic, variant 2\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"MS3_00006004 LARS2_1; putative leucine--tRNA ligase, mitochondrial\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"MS3_00004733 RARS2_3; Arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"MS3_00006083 RARS1_1; Arginine--tRNA ligase, cytoplasmic\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"MS3_00009870 MTG1_1; Mitochondrial GTPase\tK19828 MTG1; mitochondrial GTPase 1"
				},
				{
					"name":"MS3_00002717 NSUN4; 5-methylcytosine rRNA methyltransferase nsun4\tK21970 NSUN4; 5-methylcytosine rRNA methyltransferase NSUN4 [EC:2.1.1.-]"
				},
				{
					"name":"MS3_00002095 GCY-31_3; Soluble guanylate cyclase gcy-31\tK23495 RCC1L; RCC1-like G exchanging factor-like protein"
				},
				{
					"name":"MS3_00004643 TRUB2_1; TruB pseudouridine (psi) synthase 2\tK23497 TRUB2; mitochondrial mRNA pseudouridine synthase TRUB2 [EC:5.4.99.-]"
				}
				]
			}
			]
		},
		{
			"name":"Mitochondrial DNA replication factors",
			"children":[
			{
				"name":"Mitochondrial DNA polymerase",
				"children":[
				{
					"name":"MS3_00002071 hypothetical protein\tK02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Mitochondrial DNA maintenance factors",
				"children":[
				{
					"name":"MS3_00001428 CPS6; Endonuclease G, mitochondrial\tK01173 ENDOG; endonuclease G, mitochondrial"
				},
				{
					"name":"MS3_00007134 MGME1; Mitochondrial genome maintenance exonuclease 1\tK19465 MGME1; mitochondrial genome maintenance exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"MS3_00006360 PIF1_1; DNA helicase\tK15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"Other Mitochondrial DNA replication factors",
				"children":[
				{
					"name":"MS3_00001395 ATAD3A; ATPase AAA domain-containing protein 3-A, variant 2\tK17681 ATAD3A_B; ATPase family AAA domain-containing protein 3A\/B"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Mitochondrial protein import machinery",
		"children":[
		{
			"name":"Endoplasmic reticulum membrane and cytosol",
			"children":[
			{
				"name":"ER-mitochondria encounter structure (ERMES) complex"
			},
			{
				"name":"Other ER-memrane and cytosol factors",
				"children":[
				{
					"name":"MS3_00011052 RHOT2; Mitochondrial Rho GTPase 2\tK07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]"
				},
				{
					"name":"MS3_00001888 HSPA8_1; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00001889 HSPA8_2; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00001890 HSPA8_3; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00001891 HSPA8_4; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00001892 HSPA8_5; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00010192 HSPA8_6; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00010193 HSPA8_7; Heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"MS3_00001734 hypothetical protein\tK17767 AIP; AH receptor-interacting protein"
				}
				]
			}
			]
		},
		{
			"name":"Outer membrane",
			"children":[
			{
				"name":"Transporter outer membrane (TOM) complex",
				"children":[
				{
					"name":"MS3_00008642 TOMM22_1; Mitochondrial import receptor subunit TOM22\tK17769 TOM22; mitochondrial import receptor subunit TOM22"
				},
				{
					"name":"MS3_00007680 TOMM40L; Mitochondrial import receptor subunit TOM40B\tK11518 TOM40; mitochondrial import receptor subunit TOM40"
				},
				{
					"name":"MS3_00009500 TOMM70A; Mitochondrial import receptor subunit TOM70\tK17768 TOM70; mitochondrial import receptor subunit TOM70"
				}
				]
			},
			{
				"name":"TOB\/SAM complex",
				"children":[
				{
					"name":"MS3_00009638 SAMM50_1; sorting and assembly machinery component 50, variant 2\tK07277 SAM50; outer membrane protein insertion porin family"
				}
				]
			},
			{
				"name":"MIM complex"
			},
			{
				"name":"Porin",
				"children":[
				{
					"name":"MS3_00005449 VDAC1_1; Voltage-dependent anion-selective channel protein 1\tK15040 VDAC2; voltage-dependent anion channel protein 2"
				}
				]
			},
			{
				"name":"Other outer membrane factor"
			}
			]
		},
		{
			"name":"Inter membrane space",
			"children":[
			{
				"name":"Transporter inner membrane (TIM) 9\/10 complex",
				"children":[
				{
					"name":"MS3_00010027 TIMM10_1; Mitochondrial import inner membrane translocase subunit Tim10, variant 4\tK17778 TIM10; mitochondrial import inner membrane translocase subunit TIM10"
				}
				]
			},
			{
				"name":"TIM8\/13 complex"
			},
			{
				"name":"Mitochondrial intermembrane space assembly (MIA) complex"
			}
			]
		},
		{
			"name":"Inner mambrane",
			"children":[
			{
				"name":"MICOS complex",
				"children":[
				{
					"name":"MS3_00007572 hypothetical protein\tK17785 IMMT; MICOS complex subunit MIC60"
				}
				]
			},
			{
				"name":"MICOS complex (yeast)",
				"children":[
				{
					"name":"MS3_00007572 hypothetical protein\tK17785 IMMT; MICOS complex subunit MIC60"
				}
				]
			},
			{
				"name":"TIM22 complex",
				"children":[
				{
					"name":"MS3_00007937 TIMM22; Mitochondrial import inner membrane translocase subunit Tim22\tK17790 TIM22; mitochondrial import inner membrane translocase subunit TIM22"
				}
				]
			},
			{
				"name":"TIM23 complex",
				"children":[
				{
					"name":"MS3_00003490 TIMM23_1; mitochondrial import inner membrane translocase, subunit timm23, variant 2\tK17794 TIM23; mitochondrial import inner membrane translocase subunit TIM23"
				},
				{
					"name":"MS3_00007464 TIMM17A_1; Mitochondrial import inner membrane translocase subunit Tim17-A\tK17795 TIM17; mitochondrial import inner membrane translocase subunit TIM17"
				},
				{
					"name":"MS3_00003928 TIMM21_1; Mitochondrial import inner membrane translocase subunit Tim21\tK17796 TIM21; mitochondrial import inner membrane translocase subunit TIM21"
				},
				{
					"name":"MS3_00004021 TIMM50_1; Mitochondrial import inner membrane translocase subunit TIM50\tK17496 TIM50; mitochondrial import inner membrane translocase subunit TIM50"
				}
				]
			},
			{
				"name":"Mitochondrial calcium uniporter complex",
				"children":[
				{
					"name":"MS3_00003062 hypothetical protein\tK20858 MCU; calcium uniporter protein, mitochondrial"
				},
				{
					"name":"MS3_00003958 MICU1; Calcium uptake protein 1, mitochondrial\tK22827 MICU1; calcium uptake protein 1, mitochondrial"
				}
				]
			},
			{
				"name":"Other inner membrane factors",
				"children":[
				{
					"name":"MS3_00006330 LETM1_1; letm1 and EF-hand domain-containing protein 1, mitochondrial, variant 3\tK17800 LETM1; mitochondrial proton\/calcium exchanger protein"
				},
				{
					"name":"MS3_00005102 IMMP1L; IMP1 inner mitochondrial membrane peptidase-like\tK09647 IMP1; mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-]"
				},
				{
					"name":"MS3_00008605 MPC2_1; Mitochondrial pyruvate carrier 2\tK22139 MPC2; mitochondrial pyruvate carrier 2"
				},
				{
					"name":"MS3_00007388 hypothetical protein\tK28215 OCIAD1; OCIA domain-containing protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Matrix",
			"children":[
			{
				"name":"MMC\/PAM proteins",
				"children":[
				{
					"name":"MS3_00005263 HSPA9_1; Stress-70 protein, mitochondrial, variant 4\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"MS3_00007961 GRPEL1; GrpE protein 1, mitochondrial\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"MS3_00001380 DNAJC19_1; DnaJ of sub C member 19\tK09539 DNAJC19; DnaJ homolog subfamily C member 19"
				},
				{
					"name":"MS3_00005389 PAM16_1; mitochondrial import inner membrane translocase subunit TIM16\tK17805 PAM16; mitochondrial import inner membrane translocase subunit TIM16"
				}
				]
			},
			{
				"name":"Other matrix factors",
				"children":[
				{
					"name":"MS3_00010519 hypothetical protein\tK01412 PMPCA; mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64]"
				},
				{
					"name":"MS3_00001464 UQCRC1_1; mitochondrial processing peptidase beta subunit\tK17732 PMPCB; mitochondrial-processing peptidase subunit beta [EC:3.4.24.64]"
				},
				{
					"name":"MS3_00004308 hypothetical protein\tK01410 MIPEP; mitochondrial intermediate peptidase [EC:3.4.24.59]"
				},
				{
					"name":"MS3_00008075 HSPD1_1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"MS3_00000755 HSPE1; 10 kda heat shock protein\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"MS3_00005190 DNAJA3_1; DnaJ sub A member 3, mitochondrial\tK09504 DNAJA3; DnaJ homolog subfamily A member 3"
				},
				{
					"name":"MS3_00001954 TAMM41; Phosphatidate cytidylyltransferase, mitochondrial\tK17807 TAM41; mitochondrial translocator assembly and maintenance protein 41"
				},
				{
					"name":"MS3_00004973 ETHE1_1; Ethylmalonic encephalopathy 1\tK17725 ETHE1; sulfur dioxygenase [EC:1.13.11.18]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Mitochondrial quality control factors",
		"children":[
		{
			"name":"Regulator of mitochondrial biogenesis",
			"children":[
			{
				"name":"Ubiquitas transcription factors",
				"children":[
				{
					"name":"MS3_00003493 GFM2_1; G elongation factor, mitochondrial 2\tK02355 fusA; elongation factor G"
				},
				{
					"name":"MS3_00004642 GFM1_1; elongation factor EF-G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"MS3_00010187 hypothetical protein\tK09454 GABPB; GA-binding protein transcription factor, beta"
				},
				{
					"name":"MS3_00008378 hypothetical protein\tK11830 TFAM; transcription factor A, mitochondrial"
				}
				]
			},
			{
				"name":"Nuclear respiratory factors"
			},
			{
				"name":"Coactivators",
				"children":[
				{
					"name":"MS3_00000454 hypothetical protein\tK04498 EP300; E1A\/CREB-binding protein [EC:2.3.1.48]"
				}
				]
			},
			{
				"name":"Proteins involved in Fe-S cluster biogenesis",
				"children":[
				{
					"name":"MS3_00008234 NFS1_5; cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"MS3_00004479 hypothetical protein\tK22068 ISCU; iron-sulfur cluster assembly enzyme ISCU, mitochondrial"
				},
				{
					"name":"MS3_00008327 FDX1; Adrenodoxin, mitochondrial\tK22070 FDX1; ferredoxin-1, mitochondrial"
				},
				{
					"name":"MS3_00008450 FDX2_1; Ferredoxin-2, mitochondrial, variant 3\tK22071 FDX2; ferredoxin-2, mitochondrial"
				},
				{
					"name":"MS3_00003030 hypothetical protein\tK18914 FDXR; adrenodoxin-NADP+ reductase [EC:1.18.1.6]"
				},
				{
					"name":"MS3_00005263 HSPA9_1; Stress-70 protein, mitochondrial, variant 4\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"MS3_00002144 hypothetical protein\tK04082 hscB; molecular chaperone HscB"
				},
				{
					"name":"MS3_00007043 IBA57_1; Iron-sulfur clusters incorporation protein, variant 2\tK22073 IBA57; transferase CAF17, mitochondrial [EC:2.1.-.-]"
				}
				]
			},
			{
				"name":"Other regulator of mitochondrial biogenesis",
				"children":[
				{
					"name":"MS3_00004682 FBXL4_1; F-box and leucine-rich repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
				},
				{
					"name":"MS3_00005986 HCFC2_2; Host cell factor 2, variant 2\tK14966 HCFC1; host cell factor 1"
				},
				{
					"name":"MS3_00004397 SNAI2_2; Snail 2\tK04533 HD; huntingtin"
				},
				{
					"name":"MS3_00002715 PRKAA2_1; protein kinase, AMP-activated, alpha 2 catalytic subunit\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
				},
				{
					"name":"MS3_00009734 LONP1; Lon protease mitochondrial\tK08675 LONP1; ATP-dependent Lon protease [EC:3.4.21.53]"
				},
				{
					"name":"MS3_00004273 SIRT1_1; NAD-dependent protein deacetylase sirtuin-1\tK11411 SIRT1; NAD-dependent protein deacetylase sirtuin 1 [EC:2.3.1.286]"
				},
				{
					"name":"MS3_00005057 SERAC1_1; Serine active site containing protein 1, variant 2\tK23504 SERAC1; protein SERAC1"
				},
				{
					"name":"MS3_00002044 hypothetical protein\tK28271 C2ORF69; mitochondrial protein C2orf69"
				},
				{
					"name":"MS3_00003734 DDX49_1; putative ATP-dependent RNA helicase ddx49, variant 2\tK14777 DDX47; ATP-dependent RNA helicase DDX47\/RRP3 [EC:5.6.2.7]"
				},
				{
					"name":"MS3_00005985 DDX49_3; putative ATP-dependent RNA helicase ddx49\tK14777 DDX47; ATP-dependent RNA helicase DDX47\/RRP3 [EC:5.6.2.7]"
				}
				]
			}
			]
		},
		{
			"name":"Mitochondrial respiratory chain complex assembly factors",
			"children":[
			{
				"name":"Complex-I assembly factors",
				"children":[
				{
					"name":"MS3_00007899 PPME1_3; Protein phosphatase methylesterase 1\tK18159 NDUFAF1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1"
				},
				{
					"name":"MS3_00005978 NDUFAF2; Mimitin, mitochondrial\tK18160 NDUFAF2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2"
				},
				{
					"name":"MS3_00006852 MTRF1L_2; Peptide chain release factor 1-like, mitochondrial\tK18161 NDUFAF4; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4"
				},
				{
					"name":"MS3_00020005 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5\tK18162 NDUFAF5; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-]"
				},
				{
					"name":"MS3_00006214 NDUFAF7_1; NADH dehydrogenase [ubiquinone] complex I, assembly factor 7\tK18164 NDUFAF7; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7"
				},
				{
					"name":"MS3_00006284 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1\tK18166 FOXRED1; FAD-dependent oxidoreductase domain-containing protein 1"
				}
				]
			},
			{
				"name":"Complex-II assembly factors"
			},
			{
				"name":"Complex-III assembly factors",
				"children":[
				{
					"name":"MS3_00001389 BCS1L_1; mitochondrial chaperone, variant 2\tK08900 BCS1; mitochondrial chaperone BCS1"
				},
				{
					"name":"MS3_00004673 TTC19; Tetratricopeptide repeat protein 19, mitochondrial\tK18169 TTC19; tetratricopeptide repeat protein 19, mitochondrial"
				},
				{
					"name":"MS3_00001795 LYRM7; Complex III assembly factor lyrm7\tK18170 LYRM7; complex III assembly factor LYRM7"
				},
				{
					"name":"MS3_00005414 UQCC1; Ubiquinol-cytochrome-c reductase complex assembly factor 1, variant 2\tK17662 CBP3; cytochrome b pre-mRNA-processing protein 3"
				}
				]
			},
			{
				"name":"Complex-IV assembly factors",
				"children":[
				{
					"name":"MS3_00002810 hypothetical protein\tK18171 CMC1; COX assembly mitochondrial protein 1"
				},
				{
					"name":"MS3_00009213 COX10; Protoheme IX farnesyltransferase, mitochondrial\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"MS3_00003549 COX18; Cytochrome c oxidase assembly protein cox18, mitochondrial\tK17797 COX18; mitochondrial inner membrane protein COX18"
				},
				{
					"name":"MS3_00004435 SURF1_1; Surfeit locus protein 1\tK14998 SURF1; surfeit locus 1 family protein"
				},
				{
					"name":"MS3_00004680 TACO1_1; Translational activator of mitochondrially encoded cytochrome c oxidase I\tK18189 TACO1; translational activator of cytochrome c oxidase 1"
				},
				{
					"name":"MS3_00006066 APOPT1; Apoptogenic protein 1, mitochondrial\tK23506 APOPT1; apoptogenic protein 1"
				}
				]
			},
			{
				"name":"Complex-V assembly factors"
			}
			]
		},
		{
			"name":"Mitochondrial dynamics",
			"children":[
			{
				"name":"Fission and Fusion factors",
				"children":[
				{
					"name":"MS3_00001582 MFN2; Mitofusin-2\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				},
				{
					"name":"MS3_00001506 OPA1_1; Dynamin-like protein, mitochondrial, variant 3\tK17079 OPA1; optic atrophy protein 1 [EC:3.6.5.5]"
				},
				{
					"name":"MS3_00004542 hypothetical protein\tK09650 PARL; rhomboid-like protein [EC:3.4.21.105]"
				},
				{
					"name":"MS3_00003243 BAK1_1; Bcl-2 antagonist\/killer, variant 3\tK14021 BAK; Bcl-2 homologous antagonist\/killer"
				},
				{
					"name":"MS3_00010207 DNM1L; Dynamin-1-like protein\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				},
				{
					"name":"MS3_00000834 FIS1_1; mitochondrial membrane protein\tK17969 FIS1; mitochondrial fission 1 protein"
				},
				{
					"name":"MS3_00001455 FIS1_2; mitochondrial membrane protein\tK17969 FIS1; mitochondrial fission 1 protein"
				},
				{
					"name":"MS3_00002832 hypothetical protein\tK11248 SH3GLB1; endophilin-B1"
				},
				{
					"name":"MS3_00007173 MTCH-1; mitochondrial carrier\tK17885 MTCH; mitochondrial carrier"
				},
				{
					"name":"MS3_00002564 hypothetical protein\tK22076 MFF; mitochondrial fission factor"
				},
				{
					"name":"MS3_00009082 VAT1L; Type I Polyketide synthase\tK23167 VAT1; synaptic vesicle membrane protein VAT-1 [EC:1.6.5.5]"
				}
				]
			},
			{
				"name":"Actin cytoskeleton organization",
				"children":[
				{
					"name":"MS3_00004525 ACT1_1; actin, variant 2\tK05692 ACTB_G1; actin beta\/gamma 1"
				},
				{
					"name":"MS3_00008660 ACTIN1_1; Actin-1\tK05692 ACTB_G1; actin beta\/gamma 1"
				},
				{
					"name":"MS3_00008661 ACTIN1_2; Actin-1\tK05692 ACTB_G1; actin beta\/gamma 1"
				},
				{
					"name":"MS3_00008744 ARP1_3; centractin- actin- protein of the dynactin complex\tK05692 ACTB_G1; actin beta\/gamma 1"
				},
				{
					"name":"MS3_00008746 hypothetical protein\tK05692 ACTB_G1; actin beta\/gamma 1"
				},
				{
					"name":"MS3_00001926 NAA20_1; N(alpha)-acetyltransferase 20, NatB catalytic subunit, variant 2\tK17972 NAA20; N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.254]"
				},
				{
					"name":"MS3_00005361 NAA25_1; N-alpha-acetyltransferase 25, NatB auxiliary subunit, variant 2\tK17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit"
				},
				{
					"name":"MS3_00010534 NAA25_3; N-alpha-acetyltransferase 25, NatB auxiliary subunit\tK17973 NAA25; N-terminal acetyltransferase B complex non-catalytic subunit"
				}
				]
			},
			{
				"name":"Mitochondrial movement",
				"children":[
				{
					"name":"MS3_00002454 hypothetical protein\tK17080 PHB1; prohibitin 1"
				},
				{
					"name":"MS3_00004310 PHB2_1; Prohibitin-2, subunit of the prohibitin complex (Phb1p-Phb2p), variant 3\tK17081 PHB2; prohibitin 2"
				}
				]
			},
			{
				"name":"Retention of mitochondria",
				"children":[
				{
					"name":"MS3_00010207 DNM1L; Dynamin-1-like protein\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			},
			{
				"name":"Morphogenesis factors",
				"children":[
				{
					"name":"MS3_00011052 RHOT2; Mitochondrial Rho GTPase 2\tK07870 RHOT1; mitochondrial Rho GTPase 1 [EC:3.6.5.-]"
				},
				{
					"name":"MS3_00007572 hypothetical protein\tK17785 IMMT; MICOS complex subunit MIC60"
				},
				{
					"name":"MS3_00001983 hypothetical protein\tK29121 MISO1; mitochondrial inner membrane subdomain organizer 1"
				},
				{
					"name":"MS3_00009868 ALDH9A1_1; 4-trimethylaminobutyraldehyde dehydrogenase\tK17408 DAP3; small subunit ribosomal protein S29"
				},
				{
					"name":"MS3_00004404 TM2D3_1; TM2 domain-containing protein 3\tK28688 TM2D3; TM2 domain-containing protein 3"
				}
				]
			}
			]
		},
		{
			"name":"Mitophagy factors",
			"children":[
			{
				"name":"Autophagy-related proteins",
				"children":[
				{
					"name":"MS3_00004455 ATG3; E2-like enzyme\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
				},
				{
					"name":"MS3_00001475 ATG4C_1; Cysteine protease atg4c, variant 2\tK08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]"
				},
				{
					"name":"MS3_00006688 BECN1_1; Beclin-1\tK08334 BECN; beclin"
				},
				{
					"name":"MS3_00010060 hypothetical protein\tK08341 GABARAP; GABA(A) receptor-associated protein"
				},
				{
					"name":"MS3_00007891 ATG9A; Autophagy- protein 9A\tK17907 ATG9; autophagy-related protein 9"
				},
				{
					"name":"MS3_00005212 ATG10_1; E2-like conjugating enzyme atg10, variant 3\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
				},
				{
					"name":"MS3_00002004 ATG12; Ubiquitin-like protein\tK08336 ATG12; ubiquitin-like protein ATG12"
				},
				{
					"name":"MS3_00007342 hypothetical protein\tK17890 ATG16L1; autophagy-related protein 16-1"
				},
				{
					"name":"MS3_00009227 WIPI2; WD repeat domain phosphoinositide-interacting protein 2\tK17908 WIPI1_2; autophagy-related protein 18"
				}
				]
			},
			{
				"name":"Parkin-dependent mechanism factors",
				"children":[
				{
					"name":"MS3_00002629 PINK1; Kinase 1\tK05688 PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"MS3_00004542 hypothetical protein\tK09650 PARL; rhomboid-like protein [EC:3.4.21.105]"
				},
				{
					"name":"MS3_00005427 AMBRA1; WD domain, G-beta repeat\tK17985 AMBRA1; activating molecule in BECN1-regulated autophagy protein 1"
				}
				]
			},
			{
				"name":"Parkin-independent mechanism factors",
				"children":[
				{
					"name":"MS3_00000913 HSP83_1; Heat shock protein 83\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"MS3_00002074 HSP83_2; Heat shock protein 83\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"MS3_00008220 uncharacterized protein\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"MS3_00008223 HSP83_4; Heat shock protein 83\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"MS3_00009347 CDC37_1; hsp90 co-chaperone Cdc37, variant 5\tK09554 CDC37; cell division cycle protein 37"
				}
				]
			},
			{
				"name":"Other mitophagy factors",
				"children":[
				{
					"name":"MS3_00002715 PRKAA2_1; protein kinase, AMP-activated, alpha 2 catalytic subunit\tK07198 PRKAA; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
				},
				{
					"name":"MS3_00001699 ZFYVE1; Zinc finger FYVE domain-containing protein 1\tK17603 ZFYVE1; zinc finger FYVE domain-containing protein 1"
				},
				{
					"name":"MS3_00010948 hypothetical protein\tK02318 COASY; phosphopantetheine adenylyltransferase \/ dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24]"
				}
				]
			}
			]
		}
		]
	}
	]
}