{
	"name":"simp03110",
	"children":[
	{
		"name":"Heat shock proteins",
		"children":[
		{
			"name":"HSP110"
		},
		{
			"name":"HSP100",
			"children":[
			{
				"name":"C6571_15155 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA\tK03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA"
			},
			{
				"name":"C6571_12455 clpB; ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"C6571_13140 ATP-dependent Clp protease ATP-binding subunit ClpX\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
			},
			{
				"name":"C6571_04585 hslU; HslU--HslV peptidase ATPase subunit\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU"
			}
			]
		},
		{
			"name":"HSP90",
			"children":[
			{
				"name":"C6571_09465 molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
			}
			]
		},
		{
			"name":"HSP70 \/ DNAK",
			"children":[
			{
				"name":"C6571_02810 molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"C6571_17355 hscA; Fe-S protein assembly chaperone HscA\tK04044 hscA; molecular chaperone HscA"
			}
			]
		},
		{
			"name":"HSP60 \/ Chaperonin",
			"children":[
			{
				"name":"C6571_04360 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"HSP47"
		},
		{
			"name":"HSP40 \/ DNAJ",
			"children":[
			{
				"name":"C6571_02815 dnaJ; molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
			},
			{
				"name":"C6571_10715 molecular chaperone DnaJ\tK05516 cbpA; curved DNA-binding protein"
			},
			{
				"name":"C6571_17360 Fe-S protein assembly co-chaperone HscB\tK04082 hscB; molecular chaperone HscB"
			}
			]
		},
		{
			"name":"HSP33",
			"children":[
			{
				"name":"C6571_13525 redox-regulated molecular chaperone Hsp33\tK04083 hslO; molecular chaperone Hsp33"
			}
			]
		},
		{
			"name":"HSP24",
			"children":[
			{
				"name":"C6571_02805 nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE"
			}
			]
		},
		{
			"name":"HSP20",
			"children":[
			{
				"name":"C6571_13415 heat-shock protein Hsp20\tK13993 HSP20; HSP20 family protein"
			},
			{
				"name":"C6571_17805 molecular chaperone\tK13993 HSP20; HSP20 family protein"
			}
			]
		},
		{
			"name":"HSP15",
			"children":[
			{
				"name":"C6571_01370 RNA-binding protein\tK04762 hslR; ribosome-associated heat shock protein Hsp15"
			}
			]
		},
		{
			"name":"HSP10",
			"children":[
			{
				"name":"C6571_04355 co-chaperone GroES\tK04078 groES; chaperonin GroES"
			}
			]
		},
		{
			"name":"GimC"
		}
		]
	},
	{
		"name":"Other chaperones and cochaperones",
		"children":[
		{
			"name":"Calnexin \/ calreticulin"
		},
		{
			"name":"DegP \/ HtrA",
			"children":[
			{
				"name":"C6571_01575 serine protease\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			},
			{
				"name":"C6571_02955 serine peptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			}
			]
		},
		{
			"name":"AAA proteases",
			"children":[
			{
				"name":"C6571_01000 cell division protein FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"PapD",
			"children":[
			{
				"name":"C6571_05175 atpB; ATP synthase F0 subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
			},
			{
				"name":"C6571_05970 F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
			}
			]
		},
		{
			"name":"SecB",
			"children":[
			{
				"name":"C6571_12160 protein-export chaperone SecB\tK03071 secB; preprotein translocase subunit SecB"
			}
			]
		},
		{
			"name":"Sti1 \/ p60"
		},
		{
			"name":"Cdc37 \/ p50"
		},
		{
			"name":"BAG"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"C6571_06590 hypothetical protein\tK06006 cpxP; periplasmic protein CpxP\/Spy"
			},
			{
				"name":"C6571_05295 hypothetical protein\tK09796 pccA; periplasmic copper chaperone A"
			},
			{
				"name":"C6571_05300 nuclear export factor GLE1\tK09796 pccA; periplasmic copper chaperone A"
			}
			]
		}
		]
	},
	{
		"name":"Intramolecular chaperones",
		"children":[
		{
			"name":"Subtilisin family"
		},
		{
			"name":"Papain family"
		},
		{
			"name":"Other peptidases"
		},
		{
			"name":"Others"
		}
		]
	},
	{
		"name":"Protein folding catalysts",
		"children":[
		{
			"name":"Peptidyl prolyl isomerase",
			"children":[
			{
				"name":"Cyclophilin",
				"children":[
				{
					"name":"C6571_01445 peptidylprolyl isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"C6571_01450 cyclophilin\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"C6571_00510 peptidylprolyl isomerase\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"FKBP",
				"children":[
				{
					"name":"C6571_09155 peptidylprolyl isomerase\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"C6571_13830 peptidylprolyl isomerase\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"C6571_02560 peptidylprolyl isomerase\tK03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8]"
				},
				{
					"name":"C6571_08195 peptidylprolyl isomerase\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				},
				{
					"name":"C6571_13660 peptidylprolyl isomerase\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"Parvulin",
				"children":[
				{
					"name":"C6571_00025 peptidylprolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"C6571_09265 peptidylprolyl isomerase\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"C6571_07035 molecular chaperone SurA\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"Protein disulfide isomerase",
			"children":[
			{
				"name":"C6571_00900 thiol reductase thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"C6571_01235 thiol reductase thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"C6571_14420 thiol reductase thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"C6571_09740 thiol reductase thioredoxin\tK03672 trxC; thioredoxin 2 [EC:1.8.1.8]"
			},
			{
				"name":"C6571_08965 co-chaperone YbbN\tK05838 ybbN; putative thioredoxin"
			},
			{
				"name":"C6571_12155 grxC; glutaredoxin 3\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"C6571_03925 grxD; monothiol glutaredoxin, Grx4 family\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"C6571_05755 disulfide bond formation protein DsbA\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]"
			},
			{
				"name":"C6571_18700 hypothetical protein\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]"
			},
			{
				"name":"C6571_00350 disulfide bond formation protein B\tK03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]"
			},
			{
				"name":"C6571_11125 disulfide isomerase\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"C6571_18655 hypothetical protein\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			}
			]
		}
		]
	}
	]
}