{
	"name":"spaa01009",
	"children":[
	{
		"name":"Protein serine\/threonine phosphatases",
		"children":[
		{
			"name":"Phosphoprotein phosphatases (PPPs)",
			"children":[
			{
				"name":"Protein phosphatase-1",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_48993 protein phosphatase type I\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"SPAPADRAFT_59387 hypothetical protein\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"SPAPADRAFT_63430 hypothetical protein\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP1-interacting proteins (PIPs)",
					"children":[
					{
						"name":"SPAPADRAFT_130711 hypothetical protein\tK16833 PPP1R2; protein phosphatase inhibitor 2"
					},
					{
						"name":"SPAPADRAFT_60516 hypothetical protein\tK17550 PPP1R7; protein phosphatase 1 regulatory subunit 7"
					},
					{
						"name":"SPAPADRAFT_51159 hypothetical protein\tK17553 PPP1R11; protein phosphatase 1 regulatory subunit 11"
					},
					{
						"name":"SPAPADRAFT_71623 hypothetical protein\tK17560 URI1; unconventional prefoldin RPB5 interactor 1"
					},
					{
						"name":"SPAPADRAFT_52956 ATP-dependent RNA helicase DBP7\tK14806 DDX31; ATP-dependent RNA helicase DDX31\/DBP7 [EC:5.6.2.7]"
					},
					{
						"name":"SPAPADRAFT_49688 hypothetical protein\tK11498 CENPE; centromeric protein E"
					},
					{
						"name":"SPAPADRAFT_144780 hypothetical protein\tK03238 EIF2S2; translation initiation factor 2 subunit 2"
					},
					{
						"name":"SPAPADRAFT_70543 histone deacetylase HDA1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"SPAPADRAFT_63004 hypothetical protein\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
					},
					{
						"name":"SPAPADRAFT_51884 hypothetical protein\tK11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]"
					},
					{
						"name":"SPAPADRAFT_63636 hypothetical protein\tK02932 RP-L5e; large subunit ribosomal protein L5e"
					},
					{
						"name":"SPAPADRAFT_136434 DNA helicase and DNA replication licensing factor\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
					},
					{
						"name":"SPAPADRAFT_130687 myosin-5 isoform\tK10356 MYO1; myosin I"
					},
					{
						"name":"SPAPADRAFT_131846 hypothetical protein\tK20872 NEK2; serine\/threonine-protein kinase Nek2 [EC:2.7.11.1]"
					},
					{
						"name":"SPAPADRAFT_148973 hypothetical protein\tK17583 NOM1; nucleolar MIF4G domain-containing protein 1"
					},
					{
						"name":"SPAPADRAFT_148516 hypothetical protein\tK02607 ORC5; origin recognition complex subunit 5"
					},
					{
						"name":"SPAPADRAFT_141651 PFK1; phosphofructokinase alpha subunit\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"SPAPADRAFT_144542 PFK2; phosphofructokinase beta-subunit\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"SPAPADRAFT_62382 hypothetical protein\tK14849 RRP1; ribosomal RNA-processing protein 1"
					},
					{
						"name":"SPAPADRAFT_141123 hypothetical protein\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"SPAPADRAFT_151822 hypothetical protein\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-2 (PP2A)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_154183 hypothetical protein\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"SPAPADRAFT_62392 hypothetical protein\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"SPAPADRAFT_137831 protein phosphatase PP2A regulatory subunit B\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"SPAPADRAFT_150740 hypothetical protein\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other PP2-interacting proteins",
					"children":[
					{
						"name":"SPAPADRAFT_141506 hypothetical protein\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"SPAPADRAFT_49625 hypothetical protein\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"SPAPADRAFT_142674 hypothetical protein\tK17606 IGBP1; immunoglobulin-binding protein 1"
					},
					{
						"name":"SPAPADRAFT_142108 hypothetical protein\tK17607 TIPRL; type 2A phosphatase activator TIP41"
					},
					{
						"name":"SPAPADRAFT_144103 factor arrest protein 11\tK27960 STRIP; striatin-interacting protein"
					},
					{
						"name":"SPAPADRAFT_59315 hypothetical protein\tK18203 LCMT1; [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]"
					}
					]
				}
				]
			},
			{
				"name":"Calcineurin (PPP3\/ PP2B)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_57818 hypothetical protein\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"SPAPADRAFT_63056 hypothetical protein\tK06268 PPP3R; serine\/threonine-protein phosphatase 2B regulatory subunit"
					},
					{
						"name":"SPAPADRAFT_58807 hypothetical protein\tK02183 CALM; calmodulin"
					}
					]
				},
				{
					"name":"Other calcineurin-interacting proteins"
				}
				]
			},
			{
				"name":"Protein phosphatase-4",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_54445 hypothetical protein\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"SPAPADRAFT_131882 hypothetical protein\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-5",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_139867 hypothetical protein\tK04460 PPP5C; serine\/threonine-protein phosphatase 5 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP5-interacting proteins",
					"children":[
					{
						"name":"SPAPADRAFT_59934 hypothetical protein\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"SPAPADRAFT_131795 anaphase-promoting complex component\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"SPAPADRAFT_63686 hypothetical protein\tK04079 HSP90A; molecular chaperone HtpG"
					},
					{
						"name":"SPAPADRAFT_134244 SSB1; hypothetical protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"SPAPADRAFT_138204 HSP70; heat shock protein SSA1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"SPAPADRAFT_53368 heat shock protein 70, Hsp70 family\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-6",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"SPAPADRAFT_133224 hypothetical protein\tK15427 SIT4; serine\/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]"
					},
					{
						"name":"SPAPADRAFT_58878 hypothetical protein\tK17615 PPG1; serine\/threonine-protein phosphatase PPG1 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits"
				}
				]
			},
			{
				"name":"PPEF\/PP7 protein phosphatases"
			}
			]
		},
		{
			"name":"Mg2+- or Mn2+- dependent protein phosphatases (PPMs)",
			"children":[
			{
				"name":"PPM1 phosphatases (PP2C)",
				"children":[
				{
					"name":"SPAPADRAFT_71828 hypothetical protein\tK19704 PTC1; protein phosphatase PTC1 [EC:3.1.3.16]"
				},
				{
					"name":"SPAPADRAFT_59895 hypothetical protein\tK14803 PTC2_3; protein phosphatase PTC2\/3 [EC:3.1.3.16]"
				},
				{
					"name":"SPAPADRAFT_59517 hypothetical protein\tK19705 PTC4; protein phosphatase PTC4 [EC:3.1.3.16]"
				},
				{
					"name":"SPAPADRAFT_59219 hypothetical protein\tK19708 PTC6; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]"
				},
				{
					"name":"SPAPADRAFT_142659 hypothetical protein\tK17508 PTC7; protein phosphatase PTC7 [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"Pyruvate dehydrogenase phosphatases",
				"children":[
				{
					"name":"Catalytic subunit",
					"children":[
					{
						"name":"SPAPADRAFT_59287 hypothetical protein\tK01102 PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]"
					},
					{
						"name":"SPAPADRAFT_59219 hypothetical protein\tK19708 PTC6; protein phosphatase PTC6 [EC:3.1.3.16 3.1.3.43]"
					}
					]
				},
				{
					"name":"Regulatory subunit"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein tyrosine phosphatases (PTPs)",
		"children":[
		{
			"name":"Class I PTPs (Classical)",
			"children":[
			{
				"name":"Receptor PTPs"
			},
			{
				"name":"Non-receptor PTPs",
				"children":[
				{
					"name":"SPAPADRAFT_48511 hypothetical protein\tK19806 PTP2_3; tyrosine-protein phosphatase 2\/3 [EC:3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_59072 hypothetical protein\tK19806 PTP2_3; tyrosine-protein phosphatase 2\/3 [EC:3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class I PTPs (Dual specificity phosphatases)",
			"children":[
			{
				"name":"MAPK phosphatases",
				"children":[
				{
					"name":"SPAPADRAFT_146959 hypothetical protein\tK04459 DUSP2S; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_63721 hypothetical protein\tK04459 DUSP2S; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_61447 hypothetical protein\tK11240 MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"Slingshots"
			},
			{
				"name":"Phosphatase of regenerating liver (PRL)"
			},
			{
				"name":"Atypical DSPs",
				"children":[
				{
					"name":"SPAPADRAFT_54472 nitrogen starvation-induced protein phosphatase\tK14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_60105 putative tyrosine-protein phosphatase OCA1\tK18043 OCA1; tyrosine-protein phosphatase OCA1 [EC:3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_149972 tyrosine phosphatase\tK18044 OCA2; tyrosine-protein phosphatase-like protein OCA2"
				},
				{
					"name":"SPAPADRAFT_59413 hypothetical protein\tK18045 SIW14; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]"
				},
				{
					"name":"SPAPADRAFT_56058 hypothetical protein\tK18046 OCA6; tyrosine-protein phosphatase OCA6 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"CDC14",
				"children":[
				{
					"name":"SPAPADRAFT_157243 protein tyrosine phosphatase CDC14\tK06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Phosphatase and Tensin homologs (PTEN)",
				"children":[
				{
					"name":"SPAPADRAFT_158376 protein tyrosine phosphatase\tK01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]"
				}
				]
			},
			{
				"name":"Myotubularins",
				"children":[
				{
					"name":"SPAPADRAFT_139029 hypothetical protein\tK18083 MTMR6_7_8; myotubularin-related protein 6\/7\/8 [EC:3.1.3.64 3.1.3.95]"
				}
				]
			},
			{
				"name":"Suppressors of T-cell receptor signaling"
			}
			]
		},
		{
			"name":"Class II PTPs",
			"children":[
			{
				"name":"Low molecular weight PTPs (LMWPTPs)",
				"children":[
				{
					"name":"SPAPADRAFT_56873 phosphotyrosine protein phosphatase\tK14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class III PTPs",
			"children":[
			{
				"name":"CDC25s",
				"children":[
				{
					"name":"SPAPADRAFT_61885 hypothetical protein\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"HAD phosphatases",
		"children":[
		{
			"name":"Fcp\/Scp phosphatases",
			"children":[
			{
				"name":"SPAPADRAFT_140004 hypothetical protein\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"SPAPADRAFT_61804 hypothetical protein\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"SPAPADRAFT_142199 hypothetical protein\tK17617 CTDNEP1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]"
			},
			{
				"name":"SPAPADRAFT_63196 hypothetical protein\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
			}
			]
		},
		{
			"name":"MDP-1",
			"children":[
			{
				"name":"SPAPADRAFT_61931 hypothetical protein\tK17619 MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]"
			}
			]
		},
		{
			"name":"EYAs"
		},
		{
			"name":"Other HAD phosphatases",
			"children":[
			{
				"name":"SPAPADRAFT_60783 phosphoserine phosphatase\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]"
			},
			{
				"name":"SPAPADRAFT_60620 hypothetical protein\tK17623 PUDP; pseudouridine 5'-phosphatase [EC:3.1.3.96]"
			},
			{
				"name":"SPAPADRAFT_60856 hypothetical protein\tK15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]"
			}
			]
		}
		]
	}
	]
}