{
	"name":"spb00001",
	"children":[
	{
		"name":"09100 Metabolism",
		"children":[
		{
			"name":"09101 Carbohydrate metabolism",
			"children":[
			{
				"name":"00010 Glycolysis \/ Gluconeogenesis [PATH:spb00010]",
				"children":[
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"M28_Spy0183 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy1597 fba; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"M28_Spy0488 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"M28_Spy1591 pgk; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"M28_Spy1158 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"M28_Spy0960 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0847 ldh; L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1112 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase\tK00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]"
				},
				{
					"name":"M28_Spy0457 bglA; 6-phospho-beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				},
				{
					"name":"M28_Spy1066 bglA.2; beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				},
				{
					"name":"M28_Spy1354 beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				}
				]
			},
			{
				"name":"00020 Citrate cycle (TCA cycle) [PATH:spb00020]",
				"children":[
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				}
				]
			},
			{
				"name":"00030 Pentose phosphate pathway [PATH:spb00030]",
				"children":[
				{
					"name":"M28_Spy0183 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"M28_Spy0218 rpe; ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"M28_Spy1418 tkt; transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"M28_Spy1419 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"M28_Spy1649 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"M28_Spy0675 rpiA; ribose 5-phosphate isomerase\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]"
				},
				{
					"name":"M28_Spy1578 deoC; deoxyribose-phosphate aldolase\tK01619 deoC; deoxyribose-phosphate aldolase [EC:4.1.2.4]"
				},
				{
					"name":"M28_Spy0676 deoB; phosphopentomutase\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy0018 prsA; ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"M28_Spy0821 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"M28_Spy0506 kgdA; 4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"M28_Spy1112 gapN; NADP-dependent glyceraldehyde-3-phosphate dehydrogenase\tK00131 gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]"
				},
				{
					"name":"M28_Spy0505 2-dehydro-3-deoxygluconokinase\tK00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]"
				},
				{
					"name":"M28_Spy1597 fba; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				}
				]
			},
			{
				"name":"00040 Pentose and glucuronate interconversions [PATH:spb00040]",
				"children":[
				{
					"name":"M28_Spy0437 UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy0149 3-keto-L-gulonate-6-phosphate decarboxylase\tK03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]"
				},
				{
					"name":"M28_Spy0150 L-xylulose 5-phosphate 3-epimerase\tK03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]"
				},
				{
					"name":"M28_Spy0151 araD; L-ribulose-5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				},
				{
					"name":"M28_Spy0218 rpe; ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				}
				]
			},
			{
				"name":"00051 Fructose and mannose metabolism [PATH:spb00051]",
				"children":[
				{
					"name":"M28_Spy1526 scrK; fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"M28_Spy1525 pmi; mannose-6-phosphate isomerase\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy0642 fruB; 1-phosphofructokinase\tK00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]"
				},
				{
					"name":"M28_Spy1597 fba; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"M28_Spy0488 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"M28_Spy0643 fruA; PTS system, fructose-specific IIABC component\tK02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]"
				},
				{
					"name":"M28_Spy0757 PTS system, mannose\/fructose family IIA component\tK02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1468 manL; PTS system, mannose-specific IIAB component\tK02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1469 manM; PTS system, mannose-specific IIC component\tK02795 manY; mannose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0760 ptsD; PTS system, mannose\/fructose family IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy1470 manN; PTS system, mannose-specific IID component\tK02796 manZ; mannose PTS system EIID component"
				}
				]
			},
			{
				"name":"00052 Galactose metabolism [PATH:spb00052]",
				"children":[
				{
					"name":"M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"M28_Spy1345 lacZ; beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"M28_Spy1626 lacC.2; tagatose-6-phosphate kinase\tK00917 lacC; tagatose 6-phosphate kinase [EC:2.7.1.144]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy1438 lacD.1; tagatose-bisphosphate aldolase\tK01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]"
				},
				{
					"name":"M28_Spy1625 lacD.2; tagatose-bisphosphate aldolase\tK01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]"
				},
				{
					"name":"M28_Spy1440 lacB.1; galactose-6-phosphate isomerase LacB subunit\tK01819 lacA_B; galactose-6-phosphate isomerase [EC:5.3.1.26]"
				},
				{
					"name":"M28_Spy1441 lacA.1; galactose-6-phosphate isomerase LacA subunit\tK01819 lacA_B; galactose-6-phosphate isomerase [EC:5.3.1.26]"
				},
				{
					"name":"M28_Spy1627 lacB.2; galactose-6-phosphate isomerase LacB subunit\tK01819 lacA_B; galactose-6-phosphate isomerase [EC:5.3.1.26]"
				},
				{
					"name":"M28_Spy1628 lacA.2; galactose-6-phosphate isomerase LacA subunit\tK01819 lacA_B; galactose-6-phosphate isomerase [EC:5.3.1.26]"
				},
				{
					"name":"M28_Spy1622 lacG; 6-phospho-beta-galactosidase\tK01220 lacG; 6-phospho-beta-galactosidase [EC:3.2.1.85]"
				},
				{
					"name":"M28_Spy1624 lacF; PTS system, lactose-specific IIA component\tK02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1623 lacE; PTS system, lactose-specific IIBC component\tK02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1530 scrB; sucrose-6-phosphate hydrolase\tK01193 INV; beta-fructofuranosidase [EC:3.2.1.26]"
				},
				{
					"name":"M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component\tK02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component\tK02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component\tK02746 agaW; N-acetylgalactosamine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component\tK02747 agaE; N-acetylgalactosamine PTS system EIID component"
				},
				{
					"name":"M28_Spy0523 agaS; galactosamine-6-phosphate deaminase (isomerizing)\tK02082 agaS; D-galactosamine 6-phosphate deaminase\/isomerase [EC:3.5.99.-]"
				}
				]
			},
			{
				"name":"00053 Ascorbate and aldarate metabolism [PATH:spb00053]",
				"children":[
				{
					"name":"M28_Spy0437 UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1652 transcription antiterminator, BglG family\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1651 PTS system, IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy1650 putative transport protein sgaT\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy0154 metal-dependent hydrolase\tK03476 ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]"
				},
				{
					"name":"M28_Spy0149 3-keto-L-gulonate-6-phosphate decarboxylase\tK03078 ulaD; 3-dehydro-L-gulonate-6-phosphate decarboxylase [EC:4.1.1.85]"
				},
				{
					"name":"M28_Spy0150 L-xylulose 5-phosphate 3-epimerase\tK03079 ulaE; L-ribulose-5-phosphate 3-epimerase [EC:5.1.3.22]"
				},
				{
					"name":"M28_Spy0151 araD; L-ribulose-5-phosphate 4-epimerase\tK03077 araD; L-ribulose-5-phosphate 4-epimerase [EC:5.1.3.4]"
				}
				]
			},
			{
				"name":"00500 Starch and sucrose metabolism [PATH:spb00500]",
				"children":[
				{
					"name":"M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component\tK02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]"
				},
				{
					"name":"M28_Spy1530 scrB; sucrose-6-phosphate hydrolase\tK01193 INV; beta-fructofuranosidase [EC:3.2.1.26]"
				},
				{
					"name":"M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1062 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1733 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1063 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1732 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1060 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy1731 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0457 bglA; 6-phospho-beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				},
				{
					"name":"M28_Spy1066 bglA.2; beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				},
				{
					"name":"M28_Spy1354 beta-glucosidase\tK01223 E3.2.1.86B; 6-phospho-beta-glucosidase [EC:3.2.1.86]"
				},
				{
					"name":"M28_Spy1036 glgP; glycogen phosphorylase\tK00688 PYG; glycogen phosphorylase [EC:2.4.1.1]"
				},
				{
					"name":"M28_Spy1047 amyB; neopullulanase\tK01208 cd; cyclomaltodextrinase \/ maltogenic alpha-amylase \/ neopullulanase [EC:3.2.1.54 3.2.1.133 3.2.1.135]"
				},
				{
					"name":"M28_Spy1037 malM; 4-alpha-glucanotransferase\tK00705 malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]"
				},
				{
					"name":"M28_Spy1678 PTS system, glucose-specific IIABC component\tK20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]"
				},
				{
					"name":"M28_Spy1677 exodeoxyribonuclease III\tK06896 mapP; maltose 6'-phosphate phosphatase [EC:3.1.3.90]"
				},
				{
					"name":"M28_Spy1046 amyA; alpha-amylase\tK00701 cgt; cyclomaltodextrin glucanotransferase [EC:2.4.1.19]"
				},
				{
					"name":"M28_Spy1768 PTS system, trehalose-specific IIBC component\tK02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]"
				},
				{
					"name":"M28_Spy1767 dexS; trehalose-6-phosphate hydrolase\tK01226 treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"M28_Spy0183 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"M28_Spy1526 scrK; fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				}
				]
			},
			{
				"name":"00620 Pyruvate metabolism [PATH:spb00620]",
				"children":[
				{
					"name":"M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy1557 pfl; formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				},
				{
					"name":"M28_Spy0092 ackA; acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"M28_Spy0826 pta; putative phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"M28_Spy0960 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"M28_Spy1475 accC; biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy0287 acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"M28_Spy0847 ldh; L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"M28_Spy0863 ddh; D-lactate dehydrogenase\tK03778 ldhA; D-lactate dehydrogenase [EC:1.1.1.28]"
				},
				{
					"name":"M28_Spy0409 gloA; lactoylglutathione lyase\tK01759 GLO1; lactoylglutathione lyase [EC:4.4.1.5]"
				},
				{
					"name":"M28_Spy0512 hydroxyacylglutathione hydrolase\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]"
				},
				{
					"name":"M28_Spy0810 NAD-dependent malic enzyme\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]"
				},
				{
					"name":"M28_Spy0867 oadA2; oxaloacetate decarboxylase alpha chain\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]"
				},
				{
					"name":"M28_Spy0882 oadA1; oxaloacetate decarboxylase alpha chain\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]"
				},
				{
					"name":"M28_Spy0870 oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0868 putative membrane associated protein\tK01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma"
				},
				{
					"name":"M28_Spy0484 ppc; phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:spb00630]",
				"children":[
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy1609 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"M28_Spy0506 kgdA; 4-hydroxy-2-oxoglutarate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				}
				]
			},
			{
				"name":"00640 Propanoate metabolism [PATH:spb00640]",
				"children":[
				{
					"name":"M28_Spy0092 ackA; acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"M28_Spy0826 pta; putative phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy1557 pfl; formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"M28_Spy1475 accC; biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy0847 ldh; L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"M28_Spy1728 gldA; glycerol dehydrogenase\tK00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]"
				}
				]
			},
			{
				"name":"00650 Butanoate metabolism [PATH:spb00650]",
				"children":[
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1387 atoA; acetate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"M28_Spy0870 oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+]\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"M28_Spy1557 pfl; formate acetyltransferase\tK00656 E2.3.1.54; formate C-acetyltransferase [EC:2.3.1.54]"
				},
				{
					"name":"M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase\tK01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]"
				},
				{
					"name":"M28_Spy1388 D-beta-hydroxybutyrate dehydrogenase\tK00019 BDH1; 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30]"
				},
				{
					"name":"M28_Spy0811 Zn-dependent alcohol dehydrogenase and related dehydrogenase\tK18369 adh2; alcohol dehydrogenase [EC:1.1.1.-]"
				},
				{
					"name":"M28_Spy0513 acetoin dehydrogenase\tK03366 butA; meso-butanediol dehydrogenase \/ (S,S)-butanediol dehydrogenase \/ diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]"
				}
				]
			},
			{
				"name":"00660 C5-Branched dibasic acid metabolism"
			},
			{
				"name":"00562 Inositol phosphate metabolism [PATH:spb00562]",
				"children":[
				{
					"name":"M28_Spy0930 myo-inositol-1(or 4)-monophosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]"
				},
				{
					"name":"M28_Spy0349 NAD-dependent oxidoreductase\tK22230 iolU; scyllo-inositol 2-dehydrogenase (NADP+) [EC:1.1.1.-]"
				},
				{
					"name":"M28_Spy0488 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				}
				]
			},
			{
				"name":"00566 Sulfoquinovose metabolism"
			}
			]
		},
		{
			"name":"09102 Energy metabolism",
			"children":[
			{
				"name":"00190 Oxidative phosphorylation [PATH:spb00190]",
				"children":[
				{
					"name":"M28_Spy0557 atpA; ATP synthase alpha chain\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"M28_Spy0559 atpD; ATPase, beta subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"M28_Spy0558 atpG; ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"M28_Spy0556 atpH; ATP synthase delta chain\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"M28_Spy0560 atpC; ATP synthase epsilon chain\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"M28_Spy0554 atpB; ATP synthase A chain\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"M28_Spy0555 atpF; ATP synthase B chain\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"M28_Spy0553 atpE; ATP synthase C chain\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"M28_Spy0129 ntpA; V-type sodium ATP synthase subunit A\tK02117 ATPVA; V\/A-type H+\/Na+-transporting ATPase subunit A [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"M28_Spy0130 ntpB; V-type sodium ATP synthase subunit B\tK02118 ATPVB; V\/A-type H+\/Na+-transporting ATPase subunit B"
				},
				{
					"name":"M28_Spy0127 ntpC; V-type ATP synthase subunit C\tK02119 ATPVC; V\/A-type H+\/Na+-transporting ATPase subunit C"
				},
				{
					"name":"M28_Spy0131 ntpD; V-type sodium ATP synthase subunit D\tK02120 ATPVD; V\/A-type H+\/Na+-transporting ATPase subunit D"
				},
				{
					"name":"M28_Spy0126 ntpE; V-type sodium ATP synthase subunit E\tK02121 ATPVE; V\/A-type H+\/Na+-transporting ATPase subunit E"
				},
				{
					"name":"M28_Spy0128 ntpF; V-type sodium ATP synthase subunit F\tK02122 ATPVF; V\/A-type H+\/Na+-transporting ATPase subunit F"
				},
				{
					"name":"M28_Spy0123 hypothetical protein\tK02107 ATPVG; V\/A-type H+\/Na+-transporting ATPase subunit G\/H"
				},
				{
					"name":"M28_Spy0124 ntpI; V-type sodium ATP synthase subunit I\tK02123 ATPVI; V\/A-type H+\/Na+-transporting ATPase subunit I"
				},
				{
					"name":"M28_Spy0125 ntpK; V-type sodium ATP synthase subunit K\tK02124 ATPVK; V\/A-type H+\/Na+-transporting ATPase subunit K"
				},
				{
					"name":"M28_Spy0308 ppaC; manganese-dependent inorganic pyrophosphatase\tK15986 ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]"
				}
				]
			},
			{
				"name":"00195 Photosynthesis"
			},
			{
				"name":"00196 Photosynthesis - antenna proteins"
			},
			{
				"name":"00710 Carbon fixation by Calvin cycle [PATH:spb00710]",
				"children":[
				{
					"name":"M28_Spy1591 pgk; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"M28_Spy1597 fba; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"M28_Spy1418 tkt; transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"M28_Spy0675 rpiA; ribose 5-phosphate isomerase\tK01807 rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]"
				},
				{
					"name":"M28_Spy0488 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"M28_Spy0218 rpe; ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"M28_Spy1419 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"M28_Spy1649 transaldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"M28_Spy0484 ppc; phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				}
				]
			},
			{
				"name":"00720 Other carbon fixation pathways [PATH:spb00720]",
				"children":[
				{
					"name":"M28_Spy0484 ppc; phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"M28_Spy1475 accC; biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy0899 fhs.1; formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"M28_Spy1758 fhs.2; formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"M28_Spy1173 folD; methylenetetrahydrofolate dehydrogenase (NADP+)\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"M28_Spy1757 formiminotetrahydrofolate cyclodeaminase\tK01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]"
				},
				{
					"name":"M28_Spy0826 pta; putative phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"M28_Spy0092 ackA; acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				}
				]
			},
			{
				"name":"00680 Methane metabolism [PATH:spb00680]",
				"children":[
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"M28_Spy0484 ppc; phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"M28_Spy1597 fba; fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy0092 ackA; acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				},
				{
					"name":"M28_Spy0826 pta; putative phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"M28_Spy1158 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"M28_Spy0431 hypothetical protein\tK12234 cofE; coenzyme F420-0:L-glutamate ligase \/ coenzyme F420-1:gamma-L-glutamate ligase [EC:6.3.2.31 6.3.2.34]"
				}
				]
			},
			{
				"name":"00910 Nitrogen metabolism [PATH:spb00910]",
				"children":[
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy1208 arcC; carbamate kinase\tK00926 arcC; carbamate kinase [EC:2.7.2.2]"
				},
				{
					"name":"M28_Spy0195 carbonic anhydrase\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]"
				}
				]
			},
			{
				"name":"00920 Sulfur metabolism [PATH:spb00920]",
				"children":[
				{
					"name":"M28_Spy0525 phosphoesterase, DHH family protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				},
				{
					"name":"M28_Spy1646 cysE; serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"M28_Spy1370 cysM; cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				}
				]
			}
			]
		},
		{
			"name":"09103 Lipid metabolism",
			"children":[
			{
				"name":"00061 Fatty acid biosynthesis [PATH:spb00061]",
				"children":[
				{
					"name":"M28_Spy1473 accD; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy1477 accB; biotin carboxyl carrier protein of acetyl-CoA carboxylase\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"M28_Spy1475 accC; biotin carboxylase\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"M28_Spy1474 accA; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"M28_Spy0021 acpP.1; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"M28_Spy1482 acpP.2; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"M28_Spy1483 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"M28_Spy0348 short chain dehydrogenase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"M28_Spy1481 fabK; enoyl-[acyl-carrier protein] reductase (NADH)\tK02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]"
				},
				{
					"name":"M28_Spy1485 phaB; enoyl-CoA hydratase\tK18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]"
				}
				]
			},
			{
				"name":"00062 Fatty acid elongation"
			},
			{
				"name":"00071 Fatty acid degradation [PATH:spb00071]",
				"children":[
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				}
				]
			},
			{
				"name":"00073 Cutin, suberine and wax biosynthesis"
			},
			{
				"name":"00074 Mycolic acid biosynthesis [PATH:spb00074]",
				"children":[
				{
					"name":"M28_Spy1523 alr; holo-[acyl-carrier protein] synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]"
				},
				{
					"name":"M28_Spy0021 acpP.1; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"M28_Spy1482 acpP.2; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				}
				]
			},
			{
				"name":"00100 Steroid biosynthesis"
			},
			{
				"name":"00120 Primary bile acid biosynthesis"
			},
			{
				"name":"00121 Secondary bile acid biosynthesis"
			},
			{
				"name":"00140 Steroid hormone biosynthesis"
			},
			{
				"name":"00561 Glycerolipid metabolism [PATH:spb00561]",
				"children":[
				{
					"name":"M28_Spy1609 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"M28_Spy1728 gldA; glycerol dehydrogenase\tK00005 gldA; glycerol dehydrogenase [EC:1.1.1.6]"
				},
				{
					"name":"M28_Spy1424 glpK; glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"M28_Spy0020 plsX; fatty acid\/phospholipid synthesis protein\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"M28_Spy0690 putative membrane spanning protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"M28_Spy0552 diacylglycerol kinase family\tK07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]"
				},
				{
					"name":"M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				},
				{
					"name":"M28_Spy0413 glycosyltransferase\tK13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]"
				},
				{
					"name":"M28_Spy0601 phosphoglycerol transferase\tK19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]"
				}
				]
			},
			{
				"name":"00564 Glycerophospholipid metabolism [PATH:spb00564]",
				"children":[
				{
					"name":"M28_Spy0188 gpsA; glycerol-3-phosphate dehydrogenase [NAD(P)+]\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]"
				},
				{
					"name":"M28_Spy1423 glpO; alpha-glycerophosphate oxidase\tK00105 glpO; alpha-glycerophosphate oxidase [EC:1.1.3.21]"
				},
				{
					"name":"M28_Spy0690 putative membrane spanning protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"M28_Spy0552 diacylglycerol kinase family\tK07029 dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]"
				},
				{
					"name":"M28_Spy0628 glycerophosphoryl diester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"M28_Spy1663 cdsA; phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]"
				},
				{
					"name":"M28_Spy1879 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase\tK00995 PGS1; CDP-diacylglycerol---glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]"
				},
				{
					"name":"M28_Spy0252 putative lipase\tK01094 GEP4; phosphatidylglycerophosphatase [EC:3.1.3.27]"
				},
				{
					"name":"M28_Spy0898 cardiolipin synthetase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]"
				}
				]
			},
			{
				"name":"00565 Ether lipid metabolism"
			},
			{
				"name":"00600 Sphingolipid metabolism",
				"children":[
				{
					"name":"M28_Spy1345 lacZ; beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				}
				]
			},
			{
				"name":"00590 Arachidonic acid metabolism"
			},
			{
				"name":"00591 Linoleic acid metabolism"
			},
			{
				"name":"00592 alpha-Linolenic acid metabolism"
			},
			{
				"name":"01040 Biosynthesis of unsaturated fatty acids"
			}
			]
		},
		{
			"name":"09104 Nucleotide metabolism",
			"children":[
			{
				"name":"00230 Purine metabolism [PATH:spb00230]",
				"children":[
				{
					"name":"M28_Spy0352 phosphohydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				},
				{
					"name":"M28_Spy0676 deoB; phosphopentomutase\tK01839 deoB; phosphopentomutase [EC:5.4.2.7]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy0018 prsA; ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"M28_Spy0821 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"M28_Spy0024 purF; amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"M28_Spy0029 purD; phosphoribosylamine--glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]"
				},
				{
					"name":"M28_Spy0026 purN; phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"M28_Spy0023 purL; phosphoribosylformylglycinamidine synthase\tK01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]"
				},
				{
					"name":"M28_Spy0025 purM; phosphoribosylformylglycinamidine cyclo-ligase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]"
				},
				{
					"name":"M28_Spy0031 purK; phosphoribosylaminoimidazole carboxylase ATPase subunit\tK01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]"
				},
				{
					"name":"M28_Spy0030 purE; phosphoribosylaminoimidazole carboxylase catalytic subunit\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]"
				},
				{
					"name":"M28_Spy0022 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]"
				},
				{
					"name":"M28_Spy0033 purB; adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"M28_Spy0708 apt; adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"M28_Spy0678 punA; purine nucleoside phosphorylase\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"M28_Spy0679 deoD2; purine nucleoside phosphorylase\tK03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"M28_Spy0012 hpt; hypoxanthine-guanine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]"
				},
				{
					"name":"M28_Spy1890 guaB; inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"M28_Spy0293 xanthosine triphosphate pyrophosphatase\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]"
				},
				{
					"name":"M28_Spy0832 xpt; xanthine phosphoribosyltransferase\tK03816 xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]"
				},
				{
					"name":"M28_Spy0891 guaA; glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"M28_Spy0831 guaC; GMP reductase\tK00364 guaC; GMP reductase [EC:1.7.1.7]"
				},
				{
					"name":"M28_Spy1382 gmk; guanylate kinase\tK00942 gmk; guanylate kinase [EC:2.7.4.8]"
				},
				{
					"name":"M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1777 nrdD; anaerobic ribonucleoside-triphosphate reductase\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"M28_Spy1674 relA; GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"M28_Spy0659 GTP pyrophosphokinase\tK07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]"
				},
				{
					"name":"M28_Spy0823 GTP pyrophosphokinase\tK07816 E2.7.6.5; GTP pyrophosphokinase [EC:2.7.6.5]"
				},
				{
					"name":"M28_Spy0134 purA; adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"M28_Spy0064 adk; adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"M28_Spy0256 hydrolase\tK28933 yqeK; bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [EC:3.6.1.41]"
				},
				{
					"name":"M28_Spy1208 arcC; carbamate kinase\tK00926 arcC; carbamate kinase [EC:2.7.2.2]"
				}
				]
			},
			{
				"name":"00240 Pyrimidine metabolism [PATH:spb00240]",
				"children":[
				{
					"name":"M28_Spy0624 carB; carbamoyl-phosphate synthase large chain\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy0622 carA; carbamoyl-phosphate synthase small chain\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy0621 pyrB; aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"M28_Spy0689 pyrC; dihydroorotase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"M28_Spy1159 pyrD; dihydroorotate dehydrogenase\tK00226 pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]"
				},
				{
					"name":"M28_Spy0684 pyrE; orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]"
				},
				{
					"name":"M28_Spy0683 pyrF; orotidine 5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]"
				},
				{
					"name":"M28_Spy0365 pyrH; uridylate kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]"
				},
				{
					"name":"M28_Spy1599 pyrG; CTP synthase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]"
				},
				{
					"name":"M28_Spy0597 cmk; cytidylate kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]"
				},
				{
					"name":"M28_Spy1109 udk; uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]"
				},
				{
					"name":"M28_Spy1580 udp; uridine phosphorylase\tK00757 udp; uridine phosphorylase [EC:2.4.2.3]"
				},
				{
					"name":"M28_Spy0316 upp; uracil phosphoribosyltransferase\tK00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"M28_Spy0619 pyrR; bifunctional pyrimidine regulatory protein PyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"M28_Spy0915 cdd; cytidine deaminase\tK01489 cdd; cytidine deaminase [EC:3.5.4.5]"
				},
				{
					"name":"M28_Spy1777 nrdD; anaerobic ribonucleoside-triphosphate reductase\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1535 comEB; ComE operon protein 2\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"M28_Spy0319 tmk; thymidylate kinase\tK00943 tmk; dTMP kinase [EC:2.7.4.9]"
				},
				{
					"name":"M28_Spy0193 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"M28_Spy0836 tdk2; thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]"
				},
				{
					"name":"M28_Spy0668 thyA; thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"M28_Spy0827 short chain dehydrogenase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"09105 Amino acid metabolism",
			"children":[
			{
				"name":"00250 Alanine, aspartate and glutamate metabolism [PATH:spb00250]",
				"children":[
				{
					"name":"M28_Spy1505 asnB; L-asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"M28_Spy1207 asnA; aspartate--ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"M28_Spy0515 aspC; aspartate aminotransferase\tK22457 E2.6.1.14; asparagine---oxo-acid transaminase [EC:2.6.1.14]"
				},
				{
					"name":"M28_Spy1502 aspartate aminotransferase\tK14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]"
				},
				{
					"name":"M28_Spy0134 purA; adenylosuccinate synthetase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"M28_Spy0033 purB; adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"M28_Spy0621 pyrB; aspartate carbamoyltransferase\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+]\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy0624 carB; carbamoyl-phosphate synthase large chain\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy0622 carA; carbamoyl-phosphate synthase small chain\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"M28_Spy0024 purF; amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				}
				]
			},
			{
				"name":"00260 Glycine, serine and threonine metabolism [PATH:spb00260]",
				"children":[
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"M28_Spy1609 glycerate kinase\tK00865 glxK; glycerate 2-kinase [EC:2.7.1.165]"
				},
				{
					"name":"M28_Spy1158 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"M28_Spy0827 short chain dehydrogenase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy1873 sdhB; L-serine dehydratase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"M28_Spy1874 sdhA; L-serine dehydratase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				}
				]
			},
			{
				"name":"00270 Cysteine and methionine metabolism [PATH:spb00270]",
				"children":[
				{
					"name":"M28_Spy1646 cysE; serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"M28_Spy1370 cysM; cysteine synthase\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"M28_Spy0144 metB; cystathionine beta-lyase\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"M28_Spy0433 metK1; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy1100 metK2; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy0354 pfs; 5'-methylthioadenosine nucleosidase\tK01243 mtnN; adenosylhomocysteine nucleosidase [EC:3.2.2.9]"
				},
				{
					"name":"M28_Spy1106 GAF domain-containing protein\tK08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]"
				},
				{
					"name":"M28_Spy0774 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"M28_Spy1390 luxS; autoinducer-2 production protein\tK07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]"
				},
				{
					"name":"M28_Spy0693 bcaT; branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"M28_Spy0847 ldh; L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"M28_Spy1873 sdhB; L-serine dehydratase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"M28_Spy1874 sdhA; L-serine dehydratase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				}
				]
			},
			{
				"name":"00280 Valine, leucine and isoleucine degradation [PATH:spb00280]",
				"children":[
				{
					"name":"M28_Spy0693 bcaT; branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase\tK01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]"
				}
				]
			},
			{
				"name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:spb00290]",
				"children":[
				{
					"name":"M28_Spy0693 bcaT; branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"M28_Spy1502 aspartate aminotransferase\tK14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]"
				}
				]
			},
			{
				"name":"00300 Lysine biosynthesis",
				"children":[
				{
					"name":"M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				}
				]
			},
			{
				"name":"00310 Lysine degradation [PATH:spb00310]",
				"children":[
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+]\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1387 atoA; acetate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				}
				]
			},
			{
				"name":"00220 Arginine biosynthesis [PATH:spb00220]",
				"children":[
				{
					"name":"M28_Spy1211 arcB; ornithine carbamoyltransferase\tK00611 OTC; ornithine carbamoyltransferase [EC:2.1.3.3]"
				},
				{
					"name":"M28_Spy1213 arcA; arginine deiminase\tK01478 arcA; arginine deiminase [EC:3.5.3.6]"
				},
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy0624 carB; carbamoyl-phosphate synthase large chain\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy0622 carA; carbamoyl-phosphate synthase small chain\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"M28_Spy1208 arcC; carbamate kinase\tK00926 arcC; carbamate kinase [EC:2.7.2.2]"
				},
				{
					"name":"M28_Spy1502 aspartate aminotransferase\tK14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]"
				}
				]
			},
			{
				"name":"00330 Arginine and proline metabolism [PATH:spb00330]",
				"children":[
				{
					"name":"M28_Spy0685 amiC; amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]"
				},
				{
					"name":"M28_Spy0094 proC; pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]"
				},
				{
					"name":"M28_Spy1414 glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"M28_Spy1413 proA; gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				}
				]
			},
			{
				"name":"00340 Histidine metabolism [PATH:spb00340]",
				"children":[
				{
					"name":"M28_Spy1761 hutH; histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				},
				{
					"name":"M28_Spy1755 hutU; urocanate hydratase\tK01712 hutU; urocanate hydratase [EC:4.2.1.49]"
				},
				{
					"name":"M28_Spy1754 hutI; imidazolonepropionase\tK01468 hutI; imidazolonepropionase [EC:3.5.2.7]"
				},
				{
					"name":"M28_Spy1762 hutG; formiminoglutamase\tK01479 hutG; formiminoglutamase [EC:3.5.3.8]"
				},
				{
					"name":"M28_Spy1756 glutamate formiminotransferase\tK00603 fctD; glutamate formiminotransferase \/ 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]"
				}
				]
			},
			{
				"name":"00350 Tyrosine metabolism [PATH:spb00350]",
				"children":[
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				},
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				},
				{
					"name":"M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+]\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00360 Phenylalanine metabolism",
				"children":[
				{
					"name":"M28_Spy0685 amiC; amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]"
				}
				]
			},
			{
				"name":"00380 Tryptophan metabolism [PATH:spb00380]",
				"children":[
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0685 amiC; amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]"
				}
				]
			},
			{
				"name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:spb00400]",
				"children":[
				{
					"name":"M28_Spy1338 phospho-2-dehydro-3-deoxyheptonate aldolase\tK03856 AROA2; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]"
				},
				{
					"name":"M28_Spy1339 aroB; 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]"
				},
				{
					"name":"M28_Spy0603 aroD; 3-dehydroquinate dehydratase\tK03785 aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]"
				},
				{
					"name":"M28_Spy0429 aroE.2; shikimate 5-dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]"
				},
				{
					"name":"M28_Spy1092 aroK; shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]"
				},
				{
					"name":"M28_Spy1093 3-phosphoshikimate 1-carboxyvinyltransferase\tK00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]"
				},
				{
					"name":"M28_Spy0604 aroF; chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]"
				},
				{
					"name":"M28_Spy1683 trpG; anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"M28_Spy0527 chorismate mutase\tK04516 AROA1; chorismate mutase [EC:5.4.99.5]"
				}
				]
			}
			]
		},
		{
			"name":"09106 Metabolism of other amino acids",
			"children":[
			{
				"name":"00410 beta-Alanine metabolism"
			},
			{
				"name":"00430 Taurine and hypotaurine metabolism [PATH:spb00430]",
				"children":[
				{
					"name":"M28_Spy0826 pta; putative phosphotransacetylase\tK00625 pta; phosphate acetyltransferase [EC:2.3.1.8]"
				},
				{
					"name":"M28_Spy0092 ackA; acetate kinase\tK00925 ackA; acetate kinase [EC:2.7.2.1]"
				}
				]
			},
			{
				"name":"00440 Phosphonate and phosphinate metabolism"
			},
			{
				"name":"00450 Selenocompound metabolism [PATH:spb00450]",
				"children":[
				{
					"name":"M28_Spy0144 metB; cystathionine beta-lyase\tK01760 metC; cysteine-S-conjugate beta-lyase [EC:4.4.1.13]"
				},
				{
					"name":"M28_Spy0239 nifS3; cysteine desulfhydrase\tK11717 sufS; cysteine desulfurase \/ selenocysteine lyase [EC:2.8.1.7 4.4.1.16]"
				},
				{
					"name":"M28_Spy1401 thioredoxin reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"M28_Spy0332 metS; methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				}
				]
			},
			{
				"name":"00460 Cyanoamino acid metabolism [PATH:spb00460]",
				"children":[
				{
					"name":"M28_Spy1505 asnB; L-asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"M28_Spy1207 asnA; aspartate--ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				}
				]
			},
			{
				"name":"00470 D-Amino acid metabolism [PATH:spb00470]",
				"children":[
				{
					"name":"M28_Spy1522 acpS; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
				},
				{
					"name":"M28_Spy1152 ddlA; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"M28_Spy1054 dltA; D-alanine-activating enzyme\tK03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1052 D-alanyl carrier protein\tK14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy0292 glr; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				}
				]
			},
			{
				"name":"00480 Glutathione metabolism [PATH:spb00480]",
				"children":[
				{
					"name":"M28_Spy0921 pepN; lysyl aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]"
				},
				{
					"name":"M28_Spy0699 glutathione S-transferase\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]"
				},
				{
					"name":"M28_Spy0607 gor; glutathione reductase\tK00383 GSR; glutathione reductase (NADPH) [EC:1.8.1.7]"
				},
				{
					"name":"M28_Spy0482 glutathione peroxidase\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]"
				}
				]
			}
			]
		},
		{
			"name":"09107 Glycan biosynthesis and metabolism",
			"children":[
			{
				"name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:spb00520]",
				"children":[
				{
					"name":"M28_Spy0206 N-acetylmannosamine-6-phosphate 2-epimerase\tK01788 nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]"
				},
				{
					"name":"M28_Spy0351 gcaD; glucosamine-1-phosphate acetyltransferase\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]"
				},
				{
					"name":"M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"M28_Spy1431 nagA; N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"M28_Spy0742 femD; phosphoglucosamine mutase\tK03431 glmM; phosphoglucosamine mutase [EC:5.4.2.10]"
				},
				{
					"name":"M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component\tK02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component\tK02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component\tK02746 agaW; N-acetylgalactosamine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component\tK02747 agaE; N-acetylgalactosamine PTS system EIID component"
				},
				{
					"name":"M28_Spy1133 nagB; glucosamine-6-phosphate isomerase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"M28_Spy1526 scrK; fructokinase\tK00847 E2.7.1.4; fructokinase [EC:2.7.1.4]"
				},
				{
					"name":"M28_Spy0183 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"M28_Spy1525 pmi; mannose-6-phosphate isomerase\tK01809 manA; mannose-6-phosphate isomerase [EC:5.3.1.8]"
				},
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy0437 UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy0757 PTS system, mannose\/fructose family IIA component\tK02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1468 manL; PTS system, mannose-specific IIAB component\tK02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1469 manM; PTS system, mannose-specific IIC component\tK02795 manY; mannose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0760 ptsD; PTS system, mannose\/fructose family IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy1470 manN; PTS system, mannose-specific IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				}
				]
			},
			{
				"name":"00541 Biosynthesis of various nucleotide sugars [PATH:spb00541]",
				"children":[
				{
					"name":"M28_Spy0351 gcaD; glucosamine-1-phosphate acetyltransferase\tK04042 glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase \/ glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]"
				},
				{
					"name":"M28_Spy0211 nanH; N-acetylneuraminate lyase\tK01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]"
				},
				{
					"name":"M28_Spy0187 hasC.2; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy1886 hasC; UTP-glucose-1-phosphate uridylyltransferase\tK00963 UGP2; UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]"
				},
				{
					"name":"M28_Spy0437 UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy1885 hasB; UDP-glucose 6-dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"00510 N-Glycan biosynthesis"
			},
			{
				"name":"00513 Various types of N-glycan biosynthesis"
			},
			{
				"name":"00512 Mucin type O-glycan biosynthesis"
			},
			{
				"name":"00515 Mannose type O-glycan biosynthesis"
			},
			{
				"name":"00514 Other types of O-glycan biosynthesis"
			},
			{
				"name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate"
			},
			{
				"name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin"
			},
			{
				"name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate"
			},
			{
				"name":"00531 Glycosaminoglycan degradation"
			},
			{
				"name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
			},
			{
				"name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series"
			},
			{
				"name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series"
			},
			{
				"name":"00604 Glycosphingolipid biosynthesis - ganglio series"
			},
			{
				"name":"00511 Other glycan degradation [PATH:spb00511]",
				"children":[
				{
					"name":"M28_Spy1345 lacZ; beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"M28_Spy1358 alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				}
				]
			},
			{
				"name":"00540 Lipopolysaccharide biosynthesis"
			},
			{
				"name":"00542 O-Antigen repeat unit biosynthesis [PATH:spb00542]",
				"children":[
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00550 Peptidoglycan biosynthesis [PATH:spb00550]",
				"children":[
				{
					"name":"M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"M28_Spy0282 murC; UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"M28_Spy1152 ddlA; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"M28_Spy0375 dgk; diacylglycerol kinase\tK00887 dgkA; undecaprenol kinase [EC:2.7.1.66]"
				},
				{
					"name":"M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"M28_Spy0233 bacA; putative undecaprenol kinase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase\tK12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy0485 ftsW; cell division protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				},
				{
					"name":"M28_Spy0314 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase\tK05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]"
				},
				{
					"name":"M28_Spy0739 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase\tK23393 murT; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]"
				},
				{
					"name":"M28_Spy0738 putative membrane associated protein\tK07009 gatD; lipid II isoglutaminyl synthase (glutamine-hydrolysing) [EC:6.3.5.13]"
				},
				{
					"name":"M28_Spy0490 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase\tK05363 murM; serine\/alanine adding enzyme [EC:2.3.2.10]"
				},
				{
					"name":"M28_Spy0892 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase\tK05363 murM; serine\/alanine adding enzyme [EC:2.3.2.10]"
				},
				{
					"name":"M28_Spy0489 methicillin resistance expression factor\tK12554 murN; alanine adding enzyme [EC:2.3.2.-]"
				},
				{
					"name":"M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B\tK03693 pbp1b; penicillin-binding protein 1B"
				},
				{
					"name":"M28_Spy1408 division specific D,D-transpeptidase\tK12556 pbp2X; penicillin-binding protein 2X"
				}
				]
			},
			{
				"name":"00552 Teichoic acid biosynthesis [PATH:spb00552]",
				"children":[
				{
					"name":"M28_Spy0233 bacA; putative undecaprenol kinase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"M28_Spy1054 dltA; D-alanine-activating enzyme\tK03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1052 D-alanyl carrier protein\tK14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1053 DltB\tK03739 dltB; membrane protein involved in D-alanine export"
				},
				{
					"name":"M28_Spy1051 dltD; protein precursor\tK03740 dltD; D-alanine transfer protein"
				},
				{
					"name":"M28_Spy1091 transcriptional regulator, LytR family\tK01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]"
				},
				{
					"name":"M28_Spy1463 lytR; transcriptional regulator, LytR family\tK01005 tagT_U_V; polyisoprenyl-teichoic acid--peptidoglycan teichoic acid transferase [EC:2.7.8.-]"
				},
				{
					"name":"M28_Spy0601 phosphoglycerol transferase\tK19005 ltaS; lipoteichoic acid synthase [EC:2.7.8.20]"
				},
				{
					"name":"M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				}
				]
			},
			{
				"name":"00571 Lipoarabinomannan (LAM) biosynthesis"
			},
			{
				"name":"00572 Arabinogalactan biosynthesis - Mycobacterium",
				"children":[
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00543 Exopolysaccharide biosynthesis [PATH:spb00543]",
				"children":[
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"M28_Spy1646 cysE; serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				}
				]
			}
			]
		},
		{
			"name":"09108 Metabolism of cofactors and vitamins",
			"children":[
			{
				"name":"00730 Thiamine metabolism [PATH:spb00730]",
				"children":[
				{
					"name":"M28_Spy0610 nifS1; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0820 nifS2; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0611 thiI; thiamine biosynthesis protein\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"M28_Spy0217 GTPase\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"M28_Spy0219 thiamine pyrophosphokinase\tK00949 thiN; thiamine pyrophosphokinase [EC:2.7.6.2]"
				},
				{
					"name":"M28_Spy0064 adk; adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				}
				]
			},
			{
				"name":"00740 Riboflavin metabolism [PATH:spb00740]",
				"children":[
				{
					"name":"M28_Spy1467 hydrolase (HAD superfamily)\tK21064 ycsE; 5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase [EC:3.1.3.104]"
				},
				{
					"name":"M28_Spy0933 mreA; riboflavin kinase\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]"
				},
				{
					"name":"M28_Spy0812 class B acid phosphatase\tK03788 aphA; acid phosphatase (class B) [EC:3.1.3.2]"
				},
				{
					"name":"M28_Spy0352 phosphohydrolase\tK01515 nudF; ADP-ribose diphosphatase [EC:3.6.1.13 3.6.1.-]"
				}
				]
			},
			{
				"name":"00750 Vitamin B6 metabolism [PATH:spb00750]",
				"children":[
				{
					"name":"M28_Spy0895 pyridoxine kinase\tK00868 pdxK; pyridoxine kinase [EC:2.7.1.35]"
				},
				{
					"name":"M28_Spy1605 thiD; phosphomethylpyrimidine kinase\tK00868 pdxK; pyridoxine kinase [EC:2.7.1.35]"
				}
				]
			},
			{
				"name":"00760 Nicotinate and nicotinamide metabolism [PATH:spb00760]",
				"children":[
				{
					"name":"M28_Spy0168 nadC; carboxylating nicotinate-nucleotide pyrophosphorylase\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]"
				},
				{
					"name":"M28_Spy1399 nadE; nicotinate phosphoribosyltransferase\tK00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]"
				},
				{
					"name":"M28_Spy0678 punA; purine nucleoside phosphorylase\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"M28_Spy0679 deoD2; purine nucleoside phosphorylase\tK03784 deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"M28_Spy0255 nadD; nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]"
				},
				{
					"name":"M28_Spy1398 NH(3)-dependent NAD(+) synthetase\tK01916 nadE; NAD+ synthase [EC:6.3.1.5]"
				},
				{
					"name":"M28_Spy0137 nga; NAD glycohydrolase\tK18153 nga; NAD+ glycohydrolase [EC:3.2.2.5]"
				},
				{
					"name":"M28_Spy0824 ATP-NAD kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]"
				},
				{
					"name":"M28_Spy0764 gabD; succinate-semialdehyde dehydrogenase [NADP+]\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00770 Pantothenate and CoA biosynthesis [PATH:spb00770]",
				"children":[
				{
					"name":"M28_Spy0640 apbA; 2-dehydropantoate 2-reductase\tK00077 panE; 2-dehydropantoate 2-reductase [EC:1.1.1.169]"
				},
				{
					"name":"M28_Spy0917 coaA; pantothenate kinase\tK00867 coaA; type I pantothenate kinase [EC:2.7.1.33]"
				},
				{
					"name":"M28_Spy0907 dpfB; phosphopantothenate--cysteine ligase\tK21977 coaB; phosphopantothenate---cysteine ligase (CTP) [EC:6.3.2.5]"
				},
				{
					"name":"M28_Spy0908 dfp; phosphopantothenoylcysteine decarboxylase\tK01598 PPCDC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]"
				},
				{
					"name":"M28_Spy1205 phosphopantetheine adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]"
				},
				{
					"name":"M28_Spy0397 dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]"
				},
				{
					"name":"M28_Spy1523 alr; holo-[acyl-carrier protein] synthase\tK00997 acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]"
				},
				{
					"name":"M28_Spy0693 bcaT; branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				}
				]
			},
			{
				"name":"00780 Biotin metabolism [PATH:spb00780]",
				"children":[
				{
					"name":"M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"M28_Spy0348 short chain dehydrogenase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"M28_Spy1102 birA; biotin operon repressor\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				}
				]
			},
			{
				"name":"00785 Lipoic acid metabolism [PATH:spb00785]",
				"children":[
				{
					"name":"M28_Spy0906 lipoate-protein ligase A\tK16869 lipL; lipoyl-[GcvH]:protein N-lipoyltransferase [EC:2.3.1.204]"
				},
				{
					"name":"M28_Spy0737 lplB; lipoate-protein ligase A\tK03800 lplA; lipoate---protein ligase [EC:6.3.1.20]"
				},
				{
					"name":"M28_Spy0900 lplA; lipoate-protein ligase A\tK03800 lplA; lipoate---protein ligase [EC:6.3.1.20]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0730 acoA; pyruvate dehydrogenase E1 component alpha subunit\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0731 acoB; pyruvate dehydrogenase E1 component beta subunit\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"M28_Spy0732 acoC; dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				}
				]
			},
			{
				"name":"00790 Folate biosynthesis [PATH:spb00790]",
				"children":[
				{
					"name":"M28_Spy0798 folE; GTP cyclohydrolase I\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]"
				},
				{
					"name":"M28_Spy0800 folQ; dihydroneopterin aldolase\tK01633 folB; 7,8-dihydroneopterin aldolase\/epimerase\/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]"
				},
				{
					"name":"M28_Spy0801 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]"
				},
				{
					"name":"M28_Spy0799 folP; dihydropteroate synthase\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]"
				},
				{
					"name":"M28_Spy0669 dyr; dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"M28_Spy0608 folC.2; folylpolyglutamate synthase\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]"
				},
				{
					"name":"M28_Spy0797 folC.1; folylpolyglutamate synthase\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]"
				},
				{
					"name":"M28_Spy1682 para-aminobenzoate synthetase component I\tK03342 pabBC; para-aminobenzoate synthetase \/ 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]"
				}
				]
			},
			{
				"name":"00670 One carbon pool by folate [PATH:spb00670]",
				"children":[
				{
					"name":"M28_Spy0669 dyr; dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"M28_Spy0899 fhs.1; formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"M28_Spy1758 fhs.2; formate--tetrahydrofolate ligase\tK01938 fhs; formate--tetrahydrofolate ligase [EC:6.3.4.3]"
				},
				{
					"name":"M28_Spy1173 folD; methylenetetrahydrofolate dehydrogenase (NADP+)\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"M28_Spy1757 formiminotetrahydrofolate cyclodeaminase\tK01500 fchA; methenyltetrahydrofolate cyclohydrolase [EC:3.5.4.9]"
				},
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"M28_Spy0026 purN; phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"M28_Spy1756 glutamate formiminotransferase\tK00603 fctD; glutamate formiminotransferase \/ 5-formyltetrahydrofolate cyclo-ligase [EC:2.1.2.5 6.3.3.2]"
				},
				{
					"name":"M28_Spy0668 thyA; thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"M28_Spy0433 metK1; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy1100 metK2; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				}
				]
			},
			{
				"name":"00830 Retinol metabolism"
			},
			{
				"name":"00860 Porphyrin metabolism"
			},
			{
				"name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis"
			}
			]
		},
		{
			"name":"09109 Metabolism of terpenoids and polyketides",
			"children":[
			{
				"name":"00900 Terpenoid backbone biosynthesis [PATH:spb00900]",
				"children":[
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0667 mvaS.1; hydroxymethylglutaryl-CoA synthase\tK01641 HMGCS; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]"
				},
				{
					"name":"M28_Spy0666 3-hydroxy-3-methylglutaryl-coenzyme A reductase\tK00054 mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]"
				},
				{
					"name":"M28_Spy0662 mvaK1; mevalonate kinase\tK00869 MVK; mevalonate kinase [EC:2.7.1.36]"
				},
				{
					"name":"M28_Spy0664 mvaK2; phosphomevalonate kinase\tK00938 E2.7.4.2; phosphomevalonate kinase [EC:2.7.4.2]"
				},
				{
					"name":"M28_Spy0663 mvaD; diphosphomevalonate decarboxylase\tK01597 MVD; diphosphomevalonate decarboxylase [EC:4.1.1.33]"
				},
				{
					"name":"M28_Spy0665 isopentenyl-diphosphate delta-isomerase\tK01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]"
				},
				{
					"name":"M28_Spy1170 fps; dimethylallyltransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				}
				]
			},
			{
				"name":"00902 Monoterpenoid biosynthesis"
			},
			{
				"name":"00909 Sesquiterpenoid and triterpenoid biosynthesis"
			},
			{
				"name":"00904 Diterpenoid biosynthesis"
			},
			{
				"name":"00906 Carotenoid biosynthesis"
			},
			{
				"name":"00905 Brassinosteroid biosynthesis"
			},
			{
				"name":"00981 Insect hormone biosynthesis"
			},
			{
				"name":"00908 Zeatin biosynthesis"
			},
			{
				"name":"00903 Limonene degradation"
			},
			{
				"name":"00907 Pinene, camphor and geraniol degradation"
			},
			{
				"name":"01052 Type I polyketide structures"
			},
			{
				"name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides"
			},
			{
				"name":"01051 Biosynthesis of ansamycins",
				"children":[
				{
					"name":"M28_Spy1418 tkt; transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				}
				]
			},
			{
				"name":"01059 Biosynthesis of enediyne antibiotics"
			},
			{
				"name":"01056 Biosynthesis of type II polyketide backbone"
			},
			{
				"name":"01057 Biosynthesis of type II polyketide products"
			},
			{
				"name":"00253 Tetracycline biosynthesis"
			},
			{
				"name":"00523 Polyketide sugar unit biosynthesis [PATH:spb00523]",
				"children":[
				{
					"name":"M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"01054 Nonribosomal peptide structures"
			},
			{
				"name":"01053 Biosynthesis of siderophore group nonribosomal peptides"
			},
			{
				"name":"01055 Biosynthesis of vancomycin group antibiotics",
				"children":[
				{
					"name":"M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			}
			]
		},
		{
			"name":"09110 Biosynthesis of other secondary metabolites",
			"children":[
			{
				"name":"00940 Phenylpropanoid biosynthesis"
			},
			{
				"name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis"
			},
			{
				"name":"00941 Flavonoid biosynthesis"
			},
			{
				"name":"00944 Flavone and flavonol biosynthesis"
			},
			{
				"name":"00942 Anthocyanin biosynthesis"
			},
			{
				"name":"00943 Isoflavonoid biosynthesis"
			},
			{
				"name":"00946 Degradation of flavonoids"
			},
			{
				"name":"00901 Indole alkaloid biosynthesis"
			},
			{
				"name":"00403 Indole diterpene alkaloid biosynthesis"
			},
			{
				"name":"00950 Isoquinoline alkaloid biosynthesis"
			},
			{
				"name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis"
			},
			{
				"name":"00996 Biosynthesis of various alkaloids"
			},
			{
				"name":"00232 Caffeine metabolism"
			},
			{
				"name":"00965 Betalain biosynthesis"
			},
			{
				"name":"00966 Glucosinolate biosynthesis"
			},
			{
				"name":"00402 Benzoxazinoid biosynthesis"
			},
			{
				"name":"00311 Penicillin and cephalosporin biosynthesis"
			},
			{
				"name":"00332 Carbapenem biosynthesis [PATH:spb00332]",
				"children":[
				{
					"name":"M28_Spy1414 glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"M28_Spy1413 proA; gamma-glutamyl phosphate reductase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				}
				]
			},
			{
				"name":"00261 Monobactam biosynthesis"
			},
			{
				"name":"00331 Clavulanic acid biosynthesis"
			},
			{
				"name":"00521 Streptomycin biosynthesis [PATH:spb00521]",
				"children":[
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				},
				{
					"name":"M28_Spy0910 pgmA; phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy1174 phosphoglucomutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"M28_Spy0930 myo-inositol-1(or 4)-monophosphatase\tK01092 E3.1.3.25; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]"
				},
				{
					"name":"M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"M28_Spy0715 cpsFP; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"M28_Spy0581 rmlD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"00524 Neomycin, kanamycin and gentamicin biosynthesis",
				"children":[
				{
					"name":"M28_Spy1196 glcK; glucokinase\tK25026 glk; glucokinase [EC:2.7.1.2]"
				}
				]
			},
			{
				"name":"00525 Acarbose and validamycin biosynthesis [PATH:spb00525]",
				"children":[
				{
					"name":"M28_Spy0714 cpsFO; glucose-1-phosphate thymidylyltransferase\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"M28_Spy0716 cpsFQ; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00401 Novobiocin biosynthesis"
			},
			{
				"name":"00404 Staurosporine biosynthesis"
			},
			{
				"name":"00405 Phenazine biosynthesis",
				"children":[
				{
					"name":"M28_Spy1683 trpG; anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				}
				]
			},
			{
				"name":"00333 Prodigiosin biosynthesis",
				"children":[
				{
					"name":"M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"M28_Spy0348 short chain dehydrogenase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				}
				]
			},
			{
				"name":"00254 Aflatoxin biosynthesis"
			},
			{
				"name":"00975 Biosynthesis of various siderophores"
			},
			{
				"name":"00998 Biosynthesis of various antibiotics",
				"children":[
				{
					"name":"M28_Spy0021 acpP.1; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"M28_Spy1482 acpP.2; acyl carrier protein\tK02078 acpP; acyl carrier protein"
				}
				]
			},
			{
				"name":"00999 Biosynthesis of various plant secondary metabolites [PATH:spb00999]",
				"children":[
				{
					"name":"M28_Spy0433 metK1; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy1100 metK2; S-adenosylmethionine synthetase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"M28_Spy0429 aroE.2; shikimate 5-dehydrogenase\tK00014 aroE; shikimate dehydrogenase [EC:1.1.1.25]"
				}
				]
			},
			{
				"name":"00997 Biosynthesis of various other secondary metabolites"
			}
			]
		},
		{
			"name":"09111 Xenobiotics biodegradation and metabolism",
			"children":[
			{
				"name":"00362 Benzoate degradation [PATH:spb00362]",
				"children":[
				{
					"name":"M28_Spy1771 glyoxalase family protein\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]"
				},
				{
					"name":"M28_Spy0835 4-oxalocrotonate tautomerase\tK01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]"
				},
				{
					"name":"M28_Spy0870 oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00627 Aminobenzoate degradation [PATH:spb00627]",
				"children":[
				{
					"name":"M28_Spy0685 amiC; amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]"
				},
				{
					"name":"M28_Spy0287 acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1387 atoA; acetate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				}
				]
			},
			{
				"name":"00364 Fluorobenzoate degradation"
			},
			{
				"name":"00625 Chloroalkane and chloroalkene degradation [PATH:spb00625]",
				"children":[
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				}
				]
			},
			{
				"name":"00361 Chlorocyclohexane and chlorobenzene degradation",
				"children":[
				{
					"name":"M28_Spy1771 glyoxalase family protein\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]"
				}
				]
			},
			{
				"name":"00623 Toluene degradation"
			},
			{
				"name":"00622 Xylene degradation [PATH:spb00622]",
				"children":[
				{
					"name":"M28_Spy1771 glyoxalase family protein\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]"
				},
				{
					"name":"M28_Spy0835 4-oxalocrotonate tautomerase\tK01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]"
				}
				]
			},
			{
				"name":"00633 Nitrotoluene degradation"
			},
			{
				"name":"00642 Ethylbenzene degradation"
			},
			{
				"name":"00643 Styrene degradation [PATH:spb00643]",
				"children":[
				{
					"name":"M28_Spy0685 amiC; amidase family protein\tK01426 E3.5.1.4; amidase [EC:3.5.1.4]"
				},
				{
					"name":"M28_Spy1771 glyoxalase family protein\tK07104 catE; catechol 2,3-dioxygenase [EC:1.13.11.2]"
				}
				]
			},
			{
				"name":"00791 Atrazine degradation"
			},
			{
				"name":"00930 Caprolactam degradation"
			},
			{
				"name":"00363 Bisphenol degradation"
			},
			{
				"name":"00621 Dioxin degradation",
				"children":[
				{
					"name":"M28_Spy0835 4-oxalocrotonate tautomerase\tK01821 praC; 4-oxalocrotonate tautomerase [EC:5.3.2.6]"
				}
				]
			},
			{
				"name":"00626 Naphthalene degradation [PATH:spb00626]",
				"children":[
				{
					"name":"M28_Spy0040 adhA; alcohol dehydrogenase\tK13953 adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]"
				},
				{
					"name":"M28_Spy0039 alcohol dehydrogenase\tK04072 adhE; acetaldehyde dehydrogenase \/ alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]"
				}
				]
			},
			{
				"name":"00624 Polycyclic aromatic hydrocarbon degradation"
			},
			{
				"name":"00365 Furfural degradation"
			},
			{
				"name":"00984 Steroid degradation"
			},
			{
				"name":"00980 Metabolism of xenobiotics by cytochrome P450"
			},
			{
				"name":"00982 Drug metabolism - cytochrome P450"
			},
			{
				"name":"00983 Drug metabolism - other enzymes"
			}
			]
		},
		{
			"name":"09112 Not included in regular maps",
			"children":[
			{
				"name":"09113 Global maps only"
			}
			]
		}
		]
	},
	{
		"name":"09120 Genetic Information Processing",
		"children":[
		{
			"name":"09121 Transcription",
			"children":[
			{
				"name":"03020 RNA polymerase [PATH:spb03020]",
				"children":[
				{
					"name":"M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy1381 DNA-directed RNA polymerase omega chain\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain\tK03048 rpoE; DNA-directed RNA polymerase subunit delta"
				}
				]
			},
			{
				"name":"03022 Basal transcription factors"
			},
			{
				"name":"03040 Spliceosome"
			}
			]
		},
		{
			"name":"09122 Translation",
			"children":[
			{
				"name":"03010 Ribosome [PATH:spb03010]",
				"children":[
				{
					"name":"M28_SpyR0001 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0004 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0007 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0010 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0018 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0002 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0005 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0008 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0011 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0014 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0017 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0003 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0009 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0013 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0016 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_Spy0695 SSU ribosomal protein S1P\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"M28_Spy1764 rpsB; SSU ribosomal protein S2P\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"M28_Spy0049 rpsC; SSU ribosomal protein S3P\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"M28_Spy1865 rpsD; SSU ribosomal protein S4P\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"M28_Spy0060 rpsE; SSU ribosomal protein S5P\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"M28_Spy1542 rpsF; SSU ribosomal protein S6P\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"M28_Spy0225 rpsG; SSU ribosomal protein S7P\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"M28_Spy0057 rpsH; SSU ribosomal protein S8P\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"M28_Spy1634 rpsI; SSU ribosomal protein S9P\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"M28_Spy0042 rpsJ; SSU ribosomal protein S10P\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"M28_Spy0068 rpsK; SSU ribosomal protein S11P\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"M28_Spy0224 rpsL; SSU ribosomal protein S12P\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"M28_Spy0067 rpsM; SSU ribosomal protein S13P\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"M28_Spy0056 rpsN; SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"M28_Spy1582 rpsN2; SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"M28_Spy1654 SSU ribosomal protein S15P\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"M28_Spy0629 rpsP; SSU ribosomal protein S16P\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"M28_Spy0052 rpsQ; SSU ribosomal protein S17P\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"M28_Spy1540 rpsR; SSU ribosomal protein S18P\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"M28_Spy0047 rpsS; SSU ribosomal protein S19P\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"M28_Spy0918 rpsT; SSU ribosomal protein S20P\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"M28_Spy0576 SSU ribosomal protein S21P\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"M28_Spy0364 rplA; LSU ribosomal protein L1P\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"M28_Spy0046 rplB; LSU ribosomal protein L2P\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"M28_Spy0043 rplC; LSU ribosomal protein L3P\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"M28_Spy0044 rplD; LSU ribosomal protein L1E\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"M28_Spy0055 rplE; LSU ribosomal protein L5P\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"M28_Spy0058 rplF; LSU ribosomal protein L6P\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"M28_Spy1868 rplI; LSU ribosomal protein L9P\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"M28_Spy0769 rplJ; LSU ribosomal protein L10P\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"M28_Spy0363 rplK; LSU ribosomal protein L11P\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"M28_Spy0770 rplL; LSU ribosomal protein L7\/L12P\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"M28_Spy1635 rplM; LSU ribosomal protein L13P\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"M28_Spy0053 rplN; LSU ribosomal protein L14P\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"M28_Spy0062 rplO; LSU ribosomal protein L15P\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"M28_Spy0050 rplP; LSU ribosomal protein L16P\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"M28_Spy0070 rplQ; LSU ribosomal protein L17P\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"M28_Spy0059 rplR; LSU ribosomal protein L18P\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"M28_Spy0529 rplS; LSU ribosomal protein L19P\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"M28_Spy0600 rplT; LSU ribosomal protein L20P\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"M28_Spy0613 rplU; LSU ribosomal protein L21P\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"M28_Spy0048 rplV; LSU ribosomal protein L22P\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"M28_Spy0045 rplW; LSU ribosomal protein L23P\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"M28_Spy0054 rplX; LSU ribosomal protein L24P\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"M28_Spy0615 rpmA; LSU ribosomal protein L27P\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"M28_Spy1596 rpmB; LSU ribosomal protein L28P\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"M28_Spy0051 rpmC; LSU ribosomal protein L29P\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"M28_Spy0061 rpmD; LSU ribosomal protein L30P\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"M28_Spy0524 rpmE; LSU ribosomal protein L31P\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"M28_Spy1824 rpmF; LSU ribosomal protein L32P\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"M28_Spy0400 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy1738 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy1825 rpmG; LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy0205 rpmH; LSU ribosomal protein L34P\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"M28_Spy0599 rpl36; LSU ribosomal protein L35P\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"M28_Spy0066 rpmJ; LSU ribosomal protein L36P\tK02919 RP-L36; large subunit ribosomal protein L36"
				}
				]
			},
			{
				"name":"00970 Aminoacyl-tRNA biosynthesis [PATH:spb00970]",
				"children":[
				{
					"name":"M28_SpyT0001 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0011 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0029 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0042 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0057 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0062 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0009 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0019 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0045 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0048 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0060 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0067 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0043 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0061 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0065 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0003 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0013 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0055 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0064 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"M28_SpyT0040 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"M28_SpyT0047 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"M28_SpyT0033 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0050 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0066 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0007 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0017 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0026 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0031 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0039 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"M28_SpyT0027 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0032 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0051 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0005 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0008 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0015 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0018 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0053 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0059 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0004 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0014 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0054 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0063 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0021 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0022 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0035 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0025 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"M28_SpyT0036 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"M28_SpyT0010 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"M28_SpyT0020 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"M28_SpyT0023 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0028 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0034 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0058 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0006 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0016 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0049 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0052 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0038 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"M28_SpyT0037 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"M28_SpyT0046 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"M28_SpyT0002 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0012 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0030 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0056 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_Spy0197 gltX; glutamyl-tRNA synthetase\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				},
				{
					"name":"M28_Spy1496 gatA; aspartyl\/glutamyl-tRNA amidotransferase subunit A\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy1495 gatB; aspartyl\/glutamyl-tRNA amidotransferase subunit B\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy1497 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy1126 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"M28_Spy1822 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"M28_Spy0516 asnS; asnS\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy0415 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"M28_Spy1472 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"M28_Spy1643 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"M28_Spy0332 metS; methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"M28_Spy1379 methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]"
				},
				{
					"name":"M28_Spy1296 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"M28_Spy0145 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"M28_Spy1182 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"M28_Spy0474 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"M28_Spy1817 argS; arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"M28_Spy1661 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"M28_Spy1823 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy0079 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"M28_Spy1891 trsA; tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"03013 Nucleocytoplasmic transport"
			},
			{
				"name":"03015 mRNA surveillance pathway"
			},
			{
				"name":"03008 Ribosome biogenesis in eukaryotes",
				"children":[
				{
					"name":"M28_Spy0426 acpA; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			}
			]
		},
		{
			"name":"09123 Folding, sorting and degradation",
			"children":[
			{
				"name":"03060 Protein export [PATH:spb03060]",
				"children":[
				{
					"name":"M28_Spy0063 secY; protein translocase subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"M28_Spy1737 secE; protein translocase subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"M28_Spy0401 secG; protein translocase subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"M28_Spy1665 yajC; protein translocase subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"M28_Spy0202 hypothetical protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy0286 inner membrane protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy1524 secA; protein translocase subunit\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"M28_Spy0887 ffh; signal recognition particle, subunit FFH\/SRP54\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"M28_Spy0453 ftsY; cell division protein\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"M28_Spy0108 sipA; signal peptidase I protein SipA\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy0959 sipC; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy1553 spi; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy0617 lsp; lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				}
				]
			},
			{
				"name":"04141 Protein processing in endoplasmic reticulum"
			},
			{
				"name":"04130 SNARE interactions in vesicular transport"
			},
			{
				"name":"04120 Ubiquitin mediated proteolysis"
			},
			{
				"name":"04122 Sulfur relay system [PATH:spb04122]",
				"children":[
				{
					"name":"M28_Spy0610 nifS1; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0820 nifS2; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy1872 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"M28_Spy0611 thiI; thiamine biosynthesis protein\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				}
				]
			},
			{
				"name":"03050 Proteasome"
			},
			{
				"name":"03018 RNA degradation [PATH:spb03018]",
				"children":[
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"M28_Spy1648 polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"M28_Spy0402 exoribonuclease II\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"M28_Spy1148 deaD; ATP-dependent RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"M28_Spy1383 hydrolase (HAD superfamily)\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0726 Zn-dependent hydrolase\tK12574 rnj; ribonuclease J [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy1587 Zn-dependent hydrolase\tK12574 rnj; ribonuclease J [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				}
				]
			}
			]
		},
		{
			"name":"09124 Replication and repair",
			"children":[
			{
				"name":"03030 DNA replication [PATH:spb03030]",
				"children":[
				{
					"name":"M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0962 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1660 polC; DNA polymerase III alpha subunit\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1105 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0320 dnaX; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1140 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0002 dnaN; DNA polymerase III, beta chain\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1867 holB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"M28_Spy0578 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy0857 ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"M28_Spy1552 ribonuclease HIII\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03410 Base excision repair [PATH:spb03410]",
				"children":[
				{
					"name":"M28_Spy0710 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"M28_Spy0688 ung; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"M28_Spy1544 mutY; A\/G-specific adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"M28_Spy0396 fpg; formamidopyrimidine-DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
				},
				{
					"name":"M28_Spy1785 tag; DNA-3-methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"M28_Spy0327 exoA; exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03420 Nucleotide excision repair [PATH:spb03420]",
				"children":[
				{
					"name":"M28_Spy0006 trcF; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1537 uvrA; excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"M28_Spy1056 uvrB; excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"M28_Spy0765 uvrC; excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"M28_Spy0949 pcrA; DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03430 Mismatch repair [PATH:spb03430]",
				"children":[
				{
					"name":"M28_Spy1814 mutS; DNA mismatch repair protein\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"M28_Spy1549 mutS2; DNA mismatch repair protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"M28_Spy1788 mutL; DNA mismatch repair protein\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"M28_Spy0949 pcrA; DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1172 exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"M28_Spy1171 xseB; exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy0962 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1660 polC; DNA polymerase III alpha subunit\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0002 dnaN; DNA polymerase III, beta chain\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1105 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1140 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0320 dnaX; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03440 Homologous recombination [PATH:spb03440]",
				"children":[
				{
					"name":"M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1888 recF; DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"M28_Spy0019 recO; DNA repair protein\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"M28_Spy1153 recR; recombination protein\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"M28_Spy1783 recA; DNA recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1786 ruvA; holliday junction DNA helicase\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"M28_Spy0035 ruvB; holliday junction DNA helicase\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1509 recG; ATP-dependent DNA helicase\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1554 recD; exodeoxyribonuclease V alpha chain\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
				},
				{
					"name":"M28_Spy0962 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1660 polC; DNA polymerase III alpha subunit\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0002 dnaN; DNA polymerase III, beta chain\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1105 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1140 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0320 dnaX; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1380 priA; primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03450 Non-homologous end-joining"
			},
			{
				"name":"03460 Fanconi anemia pathway"
			}
			]
		},
		{
			"name":"09126 Chromosome",
			"children":[
			{
				"name":"03082 ATP-dependent chromatin remodeling"
			},
			{
				"name":"03083 Polycomb repressive complex"
			}
			]
		},
		{
			"name":"09125 Information processing in viruses",
			"children":[
			{
				"name":"03230 Viral genome structure"
			},
			{
				"name":"03240 Viral replication"
			},
			{
				"name":"03250 Viral life cycle - HIV-1 [PATH:spb03250]",
				"children":[
				{
					"name":"M28_Spy0360 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"03260 Virion - Human immunodeficiency virus"
			},
			{
				"name":"03271 Virion - Rotavirus"
			},
			{
				"name":"03262 Virion - Coronavirus"
			},
			{
				"name":"03261 Virion - Influenza virus"
			},
			{
				"name":"03263 Virion - Enterovirus"
			},
			{
				"name":"03264 Virion - Flavivirus and Alphavirus"
			},
			{
				"name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus"
			},
			{
				"name":"03273 Virion - Lassa virus and SFTS virus"
			},
			{
				"name":"03272 Virion - Hepatitis viruses"
			},
			{
				"name":"03266 Virion - Herpesvirus"
			},
			{
				"name":"03268 Virion - Orthopoxvirus"
			},
			{
				"name":"03267 Virion - Adenovirus"
			},
			{
				"name":"03259 Virion - Bacteriophages T4 and T7"
			},
			{
				"name":"03258 Virion - Bacteriophage lambda"
			}
			]
		}
		]
	},
	{
		"name":"09130 Environmental Information Processing",
		"children":[
		{
			"name":"09131 Membrane transport",
			"children":[
			{
				"name":"02010 ABC transporters [PATH:spb02010]",
				"children":[
				{
					"name":"M28_Spy0763 iron(III)-binding protein\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0806 spermidine\/putrescine-binding protein\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0805 potC; spermidine\/putrescine transport system permease protein\tK11070 potC; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"M28_Spy0804 potB; spermidine\/putrescine transport system permease protein\tK11071 potB; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"M28_Spy0803 potA; spermidine\/putrescine transport ATP-binding protein\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]"
				},
				{
					"name":"M28_Spy0156 opuABC; glycine betaine-binding protein\tK02001 proW; glycine betaine\/proline transport system permease protein"
				},
				{
					"name":"M28_Spy0155 opuAA; glycine betaine transport ATP-binding protein\tK02000 proV; glycine betaine\/proline transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"M28_Spy0830 glycine betaine transport system permease protein\tK05845 opuC; osmoprotectant transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0829 proV; glycine betaine transport ATP-binding protein\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"M28_Spy1670 msmK; multiple sugar transport ATP-binding protein\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"M28_Spy1039 malE; maltose\/maltodextrin-binding protein\tK15770 cycB; arabinogalactan oligomer \/ maltooligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1048 malX; maltose\/maltodextrin-binding protein\tK15770 cycB; arabinogalactan oligomer \/ maltooligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1040 malF; maltose transport system permease protein\tK15771 ganP; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1045 malC; maltose transport system permease protein\tK15771 ganP; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1041 malG; maltose transport system permease protein\tK15772 ganQ; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1044 malD; maltodextrin transport system permease protein\tK15772 ganQ; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1349 sugar-binding protein\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1351 sugar transport system permease protein\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"M28_Spy1350 sugar transport system permease protein\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"M28_Spy0135 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"M28_Spy0914 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"M28_Spy0912 nucleoside transport system permease protein\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"M28_Spy0911 nucleoside transport system permease protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"M28_Spy0913 nucleoside transport ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0928 pstS; phosphate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0927 pstC; phosphate transport system permease protein\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"M28_Spy0926 pstA; phosphate transport system permease protein\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"M28_Spy0924 pstB; phosphate transport ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"M28_Spy0925 pstB2; phosphate transport ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"M28_Spy1057 glnH; transporter\tK10036 glnH; glutamine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1058 glnQ.2; glutamine transport ATP-binding protein\tK10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0262 ABC transporter substrate-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0686 cystine-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0687 cystine transport system permease protein\tK10009 tcyB; L-cystine transport system permease protein"
				},
				{
					"name":"M28_Spy1404 amino acid ABC transporter permease protein\tK10009 tcyB; L-cystine transport system permease protein"
				},
				{
					"name":"M28_Spy1403 transporter\tK10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0575 arginine-binding protein\tK23059 artP; arginine\/lysine\/histidine transporter system substrate-binding protein"
				},
				{
					"name":"M28_Spy1177 artQ; arginine transport system permease protein\tK17077 artQ; arginine\/lysine\/histidine transport system permease protein"
				},
				{
					"name":"M28_Spy1176 artP; arginine transport ATP-binding protein\tK23060 artR; arginine\/lysine\/histidine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0230 ABC transporter amino acid-binding protein\tK17073 lysX1; putative lysine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0229 amino acid transport ATP-binding protein\tK17076 lysY; putative lysine transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0263 ABC transporter substrate-binding protein\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0265 ABC transporter permease protein\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"M28_Spy0264 ABC transporter ATP-binding protein\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0244 oppA; oligopeptide-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0245 oppB; oligopeptide transport system permease protein\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0246 oppC; oligopeptide transport system permease protein\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0247 oppD; oligopeptide transport ATP-binding protein\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0248 oppF; oligopeptide transport ATP-binding protein\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0521 high-affinity zinc uptake system protein ZnuA precursor\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1696 lmb; laminin binding protein\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0077 adcB; high-affinity zinc uptake system membrane protein\tK09816 znuB; zinc transport system permease protein"
				},
				{
					"name":"M28_Spy0076 adcC; high-affinity zinc uptake system ATP-binding protein\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]"
				},
				{
					"name":"M28_Spy0357 mtsA; manganese-binding protein\tK11704 mtsA; iron\/zinc\/manganese\/copper transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0359 mtsC; manganese transport system membrane protein\tK11705 mtsC; iron\/zinc\/manganese\/copper transport system permease protein"
				},
				{
					"name":"M28_Spy0358 mtsB; manganese transport system ATP-binding protein\tK11706 mtsB; iron\/zinc\/manganese\/copper transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0175 BioY\tK03523 bioY; biotin transport system substrate-specific component"
				},
				{
					"name":"M28_Spy1512 cobalt transport protein cbiQ\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"M28_Spy1876 cbiQ; cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"M28_Spy1878 cbiO1; cobalt transport ATP-binding protein\tK16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"M28_Spy1877 cbiO2; cobalt transport ATP-binding protein\tK16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"M28_Spy0786 srtE; lantibiotic transport permease protein\tK20491 nisE; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0787 srtG; lantibiotic transport permease protein\tK20492 nisG; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0785 srtF; lantibiotic transport ATP-binding protein\tK20490 nisF; lantibiotic transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0511 ftsX; cell division protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"M28_Spy0510 ftsE; cell division ATP-binding protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0190 ABC transporter ATP-binding and permease protein\tK18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0191 ABC transporter ATP-binding and permease protein\tK18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0844 multidrug resistance ABC transporter ATP-binding and permease protein\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0845 multidrug resistance ABC transporter ATP-binding and permease protein\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				}
				]
			},
			{
				"name":"02060 Phosphotransferase system (PTS) [PATH:spb02060]",
				"children":[
				{
					"name":"M28_Spy1113 pstI; phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"M28_Spy1114 ptsH; phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"M28_Spy1678 PTS system, glucose-specific IIABC component\tK20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]"
				},
				{
					"name":"M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component\tK02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]"
				},
				{
					"name":"M28_Spy0456 PTS system, beta-glucoside-specific IIABC component\tK02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy1768 PTS system, trehalose-specific IIBC component\tK02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]"
				},
				{
					"name":"M28_Spy1624 lacF; PTS system, lactose-specific IIA component\tK02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1623 lacE; PTS system, lactose-specific IIBC component\tK02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1062 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1733 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1063 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1732 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1060 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy1731 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0757 PTS system, mannose\/fructose family IIA component\tK02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1468 manL; PTS system, mannose-specific IIAB component\tK02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1469 manM; PTS system, mannose-specific IIC component\tK02795 manY; mannose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0760 ptsD; PTS system, mannose\/fructose family IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy1470 manN; PTS system, mannose-specific IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy0758 ptsB; PTS system, mannose\/fructose family IIB component\tK19507 gfrB; fructoselysine\/glucoselysine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0759 ptsC; PTS system, mannose\/fructose family IIC component\tK19508 gfrC; fructoselysine\/glucoselysine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component\tK02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component\tK02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component\tK02746 agaW; N-acetylgalactosamine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component\tK02747 agaE; N-acetylgalactosamine PTS system EIID component"
				},
				{
					"name":"M28_Spy1444 PTS system, galactose-specific IIA component\tK20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]"
				},
				{
					"name":"M28_Spy1443 PTS system, galactose-specific IIB component\tK20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]"
				},
				{
					"name":"M28_Spy1442 PTS system, galactose-specific IIC component\tK20114 gatC; galactose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1652 transcription antiterminator, BglG family\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1651 PTS system, IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy1650 putative transport protein sgaT\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy0643 fruA; PTS system, fructose-specific IIABC component\tK02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]"
				},
				{
					"name":"M28_Spy0642 fruB; 1-phosphofructokinase\tK00882 fruK; 1-phosphofructokinase [EC:2.7.1.56]"
				}
				]
			},
			{
				"name":"03070 Bacterial secretion system [PATH:spb03070]",
				"children":[
				{
					"name":"M28_Spy1737 secE; protein translocase subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"M28_Spy0401 secG; protein translocase subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"M28_Spy0063 secY; protein translocase subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"M28_Spy1665 yajC; protein translocase subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"M28_Spy0202 hypothetical protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy0286 inner membrane protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy1524 secA; protein translocase subunit\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"M28_Spy0453 ftsY; cell division protein\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"M28_Spy0887 ffh; signal recognition particle, subunit FFH\/SRP54\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				}
				]
			}
			]
		},
		{
			"name":"09132 Signal transduction",
			"children":[
			{
				"name":"02020 Two-component system [PATH:spb02020]",
				"children":[
				{
					"name":"M28_Spy0928 pstS; phosphate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1898 htrA; protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"M28_Spy0424 vicK; two-component sensor histidine kinase\tK07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0423 vicR; two-component response regulator\tK07668 vicR; two-component system, OmpR family, response regulator VicR"
				},
				{
					"name":"M28_Spy0001 dnaA; chromosomal replication initiator protein\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"M28_Spy1054 dltA; D-alanine-activating enzyme\tK03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1053 DltB\tK03739 dltB; membrane protein involved in D-alanine export"
				},
				{
					"name":"M28_Spy1052 D-alanyl carrier protein\tK14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1051 dltD; protein precursor\tK03740 dltD; D-alanine transfer protein"
				},
				{
					"name":"M28_Spy0919 ciaH; sensor protein\tK14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0920 ciaR; transcriptional regulatory protein\tK14983 ciaR; two-component system, OmpR family, response regulator CiaR"
				},
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				},
				{
					"name":"M28_Spy0275 covS; CsrS\tK18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0274 covR; TCS DNA-binding response regulator, control of virulence CovR\tK18941 arlR; two-component system, OmpR family, response regulator ArlR"
				},
				{
					"name":"M28_Spy1708 ihk; two component system histidine kinase\tK18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1709 irr; two-component response regulator\tK18987 irr; two-component system, OmpR family, response regulator Irr"
				},
				{
					"name":"M28_Spy0780 srtK; sensor protein\tK20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK\/SpaK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0779 srtR; two-component response regulator\tK20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR\/SpaR"
				},
				{
					"name":"M28_Spy0781 srtA; lantibiotic\tK20482 nisA; lantibiotic bacteriocin"
				},
				{
					"name":"M28_Spy0784 serine (threonine) dehydratase\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"M28_Spy0783 lanthionine synthetase\tK20484 lanC; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated\tK20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT\/SpaT"
				},
				{
					"name":"M28_Spy0785 srtF; lantibiotic transport ATP-binding protein\tK20490 nisF; lantibiotic transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0786 srtE; lantibiotic transport permease protein\tK20491 nisE; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0787 srtG; lantibiotic transport permease protein\tK20492 nisG; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0883 citC; [citrate [pro-3S]-lyase] ligase\tK01910 citC; [citrate (pro-3S)-lyase] ligase [EC:6.2.1.22]"
				},
				{
					"name":"M28_Spy0878 citD; citrate lyase acyl carrier protein\tK01646 citD; citrate lyase subunit gamma (acyl carrier protein)"
				},
				{
					"name":"M28_Spy0879 citE; citrate lyase beta chain\tK01644 citE; citrate lyase subunit beta \/ citryl-CoA lyase [EC:4.1.3.34]"
				},
				{
					"name":"M28_Spy0880 citF; citrate lyase alpha chain\tK01643 citF; citrate lyase subunit alpha \/ citrate CoA-transferase [EC:2.8.3.10]"
				},
				{
					"name":"M28_Spy0881 citX; apo-citrate lyase phosphoribosyl-dephospho-CoA transferase\tK05964 citX; holo-ACP synthase [EC:2.7.7.61]"
				},
				{
					"name":"M28_Spy0871 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase\tK05966 citG; triphosphoribosyl-dephospho-CoA synthase [EC:2.4.2.52]"
				},
				{
					"name":"M28_Spy0810 NAD-dependent malic enzyme\tK00027 ME2; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]"
				},
				{
					"name":"M28_Spy0809 malP; malate-sodium symport\tK11616 maeN; malate:Na+ symporter"
				},
				{
					"name":"M28_Spy0198 fasB; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0199 fasC; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1359 rocA; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0200 fasA; response regulator\tK07707 agrA; two-component system, LytTR family, response regulator AgrA"
				},
				{
					"name":"M28_Spy0251 comX; competence-specific sigma factor ComX\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"M28_Spy1607 comX.2; competence-specific sigma factor\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"M28_Spy1129 oxalate\/formate antiporter\tK08177 oxlT; MFS transporter, OFA family, oxalate\/formate antiporter"
				},
				{
					"name":"M28_Spy0010 hypothetical protein\tK01467 ampC; beta-lactamase class C [EC:3.5.2.6]"
				},
				{
					"name":"M28_Spy1374 yvqE; two-component sensor protein\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1373 yvqC; two-component response regulator\tK11618 liaR; two-component system, NarL family, response regulator LiaR"
				},
				{
					"name":"M28_Spy1616 sensory transduction protein kinase\tK14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK"
				},
				{
					"name":"M28_Spy1615 salR; transcriptional regulatory protein\tK14989 salR; two-component system, NarL family, secretion system response regulator SalR"
				},
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy0118 atoD.2; acetate CoA-transferase alpha subunit AtoD\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1386 atoD.1; acetate CoA-transferase alpha subunit\tK01034 atoD; acetate CoA\/acetoacetate CoA-transferase alpha subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0119 atoA; acetyl-CoA:acetoacetyl-CoA transferase beta subunit AtoA\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy1387 atoA; acetate CoA-transferase beta subunit\tK01035 atoA; acetate CoA\/acetoacetate CoA-transferase beta subunit [EC:2.8.3.8 2.8.3.9]"
				},
				{
					"name":"M28_Spy0115 atoE; short-chain fatty acids transporter\tK02106 atoE; short-chain fatty acids transporter"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1218 yesM; two-component system sensor kinase YesM\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1347 two-component sensor kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0762 two-component response regulator\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"M28_Spy1346 two-component response regulator\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"M28_Spy0036 protein tyrosine phosphatase\tK25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"04010 MAPK signaling pathway"
			},
			{
				"name":"04013 MAPK signaling pathway - fly"
			},
			{
				"name":"04016 MAPK signaling pathway - plant"
			},
			{
				"name":"04011 MAPK signaling pathway - yeast"
			},
			{
				"name":"04012 ErbB signaling pathway"
			},
			{
				"name":"04014 Ras signaling pathway"
			},
			{
				"name":"04015 Rap1 signaling pathway"
			},
			{
				"name":"04310 Wnt signaling pathway"
			},
			{
				"name":"04330 Notch signaling pathway"
			},
			{
				"name":"04340 Hedgehog signaling pathway"
			},
			{
				"name":"04341 Hedgehog signaling pathway - fly"
			},
			{
				"name":"04350 TGF-beta signaling pathway"
			},
			{
				"name":"04390 Hippo signaling pathway"
			},
			{
				"name":"04391 Hippo signaling pathway - fly"
			},
			{
				"name":"04392 Hippo signaling pathway - multiple species"
			},
			{
				"name":"04370 VEGF signaling pathway"
			},
			{
				"name":"04371 Apelin signaling pathway"
			},
			{
				"name":"04630 JAK-STAT signaling pathway"
			},
			{
				"name":"04064 NF-kappa B signaling pathway"
			},
			{
				"name":"04668 TNF signaling pathway"
			},
			{
				"name":"04066 HIF-1 signaling pathway"
			},
			{
				"name":"04068 FoxO signaling pathway"
			},
			{
				"name":"04020 Calcium signaling pathway"
			},
			{
				"name":"04070 Phosphatidylinositol signaling system"
			},
			{
				"name":"04072 Phospholipase D signaling pathway"
			},
			{
				"name":"04071 Sphingolipid signaling pathway"
			},
			{
				"name":"04024 cAMP signaling pathway"
			},
			{
				"name":"04022 cGMP-PKG signaling pathway"
			},
			{
				"name":"04151 PI3K-Akt signaling pathway"
			},
			{
				"name":"04152 AMPK signaling pathway"
			},
			{
				"name":"04150 mTOR signaling pathway"
			},
			{
				"name":"04075 Plant hormone signal transduction"
			}
			]
		},
		{
			"name":"09133 Signaling molecules and interaction",
			"children":[
			{
				"name":"04080 Neuroactive ligand-receptor interaction"
			},
			{
				"name":"04082 Neuroactive ligand signaling"
			},
			{
				"name":"04081 Hormone signaling"
			},
			{
				"name":"04060 Cytokine-cytokine receptor interaction"
			},
			{
				"name":"04061 Viral protein interaction with cytokine and cytokine receptor"
			},
			{
				"name":"04512 ECM-receptor interaction"
			},
			{
				"name":"04514 Cell adhesion molecule (CAM) interaction"
			},
			{
				"name":"04517 IgSF CAM signaling"
			},
			{
				"name":"04518 Integrin signaling"
			},
			{
				"name":"04519 Cadherin signaling"
			}
			]
		}
		]
	},
	{
		"name":"09140 Cellular Processes",
		"children":[
		{
			"name":"09141 Transport and catabolism",
			"children":[
			{
				"name":"04144 Endocytosis"
			},
			{
				"name":"04145 Phagocytosis"
			},
			{
				"name":"04142 Lysosome biogenesis",
				"children":[
				{
					"name":"M28_Spy1355 hyl; hyaluronoglucosaminidase\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
				}
				]
			},
			{
				"name":"04146 Peroxisome [PATH:spb04146]",
				"children":[
				{
					"name":"M28_Spy0662 mvaK1; mevalonate kinase\tK00869 MVK; mevalonate kinase [EC:2.7.1.36]"
				},
				{
					"name":"M28_Spy1139 sodA; superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]"
				},
				{
					"name":"M28_Spy0421 long-chain-fatty-acid--CoA ligase"
				}
				]
			},
			{
				"name":"04149 Peroxisome - yeast"
			},
			{
				"name":"04140 Autophagy - animal"
			},
			{
				"name":"04138 Autophagy - yeast"
			},
			{
				"name":"04136 Autophagy - other"
			},
			{
				"name":"04137 Mitophagy - animal"
			},
			{
				"name":"04139 Mitophagy - yeast"
			},
			{
				"name":"04148 Efferocytosis"
			}
			]
		},
		{
			"name":"09143 Cell growth and death",
			"children":[
			{
				"name":"04110 Cell cycle"
			},
			{
				"name":"04111 Cell cycle - yeast"
			},
			{
				"name":"04112 Cell cycle - Caulobacter"
			},
			{
				"name":"04113 Meiosis - yeast"
			},
			{
				"name":"04114 Oocyte meiosis"
			},
			{
				"name":"04210 Apoptosis"
			},
			{
				"name":"04214 Apoptosis - fly"
			},
			{
				"name":"04215 Apoptosis - multiple species"
			},
			{
				"name":"04216 Ferroptosis"
			},
			{
				"name":"04217 Necroptosis"
			},
			{
				"name":"04115 p53 signaling pathway"
			},
			{
				"name":"04218 Cellular senescence"
			},
			{
				"name":"04156 Integrated stress response (ISR) signaling pathway [PATH:spb04156]",
				"children":[
				{
					"name":"M28_SpyT0021 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0022 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0035 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				}
				]
			}
			]
		},
		{
			"name":"09144 Cellular community - eukaryotes",
			"children":[
			{
				"name":"04510 Focal adhesion"
			},
			{
				"name":"04520 Adherens junction"
			},
			{
				"name":"04530 Tight junction"
			},
			{
				"name":"04540 Gap junction"
			},
			{
				"name":"04550 Signaling pathways regulating pluripotency of stem cells"
			}
			]
		},
		{
			"name":"09145 Cellular community - prokaryotes",
			"children":[
			{
				"name":"02024 Quorum sensing [PATH:spb02024]",
				"children":[
				{
					"name":"M28_Spy1390 luxS; autoinducer-2 production protein\tK07173 luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]"
				},
				{
					"name":"M28_Spy1683 trpG; anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"M28_Spy0198 fasB; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0199 fasC; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1359 rocA; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0200 fasA; response regulator\tK07707 agrA; two-component system, LytTR family, response regulator AgrA"
				},
				{
					"name":"M28_Spy0139 slo; streptolysin O\tK11031 slo; thiol-activated cytolysin"
				},
				{
					"name":"M28_Spy0919 ciaH; sensor protein\tK14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0920 ciaR; transcriptional regulatory protein\tK14983 ciaR; two-component system, OmpR family, response regulator CiaR"
				},
				{
					"name":"M28_Spy0244 oppA; oligopeptide-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0245 oppB; oligopeptide transport system permease protein\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0246 oppC; oligopeptide transport system permease protein\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0247 oppD; oligopeptide transport ATP-binding protein\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0248 oppF; oligopeptide transport ATP-binding protein\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0034 comR; competence transcriptional regulator ComR\tK20342 comR; HTH-type transcriptional regulator, regulator for ComX"
				},
				{
					"name":"M28_Spy0251 comX; competence-specific sigma factor ComX\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"M28_Spy1607 comX.2; competence-specific sigma factor\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"M28_Spy0395 mutR; transcriptional regulator\tK20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator"
				},
				{
					"name":"M28_Spy0428 transcriptional regulator\tK20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor"
				},
				{
					"name":"M28_Spy1689 dppA; dipeptide-binding protein\tK02035 ABC.PE.S; peptide\/nickel transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1690 dppB; dipeptide transport system permease protein\tK02033 ABC.PE.P; peptide\/nickel transport system permease protein"
				},
				{
					"name":"M28_Spy1691 dppC; dipeptide transport system permease protein\tK02034 ABC.PE.P1; peptide\/nickel transport system permease protein"
				},
				{
					"name":"M28_Spy1692 dppD; dipeptide transport ATP-binding protein\tK02031 ddpD; peptide\/nickel transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1693 dppE; dipeptide transport ATP-binding protein\tK02032 ddpF; peptide\/nickel transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1724 rgg; transcriptional regulator\tK20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator"
				},
				{
					"name":"M28_Spy1721 speB; pyrogenic exotoxin B\tK01364 speB; streptopain [EC:3.4.22.10]"
				},
				{
					"name":"M28_Spy1438 lacD.1; tagatose-bisphosphate aldolase\tK01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]"
				},
				{
					"name":"M28_Spy1625 lacD.2; tagatose-bisphosphate aldolase\tK01635 lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]"
				},
				{
					"name":"M28_Spy0202 hypothetical protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy0286 inner membrane protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy1737 secE; protein translocase subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"M28_Spy0401 secG; protein translocase subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"M28_Spy0063 secY; protein translocase subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"M28_Spy1665 yajC; protein translocase subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"M28_Spy1524 secA; protein translocase subunit\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"M28_Spy0453 ftsY; cell division protein\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"M28_Spy0887 ffh; signal recognition particle, subunit FFH\/SRP54\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"M28_Spy0781 srtA; lantibiotic\tK20482 nisA; lantibiotic bacteriocin"
				},
				{
					"name":"M28_Spy0784 serine (threonine) dehydratase\tK20483 lanB; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"M28_Spy0783 lanthionine synthetase\tK20484 lanC; class I lanthipeptide synthase [EC:3.13.2.4]"
				},
				{
					"name":"M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated\tK20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT\/SpaT"
				},
				{
					"name":"M28_Spy0780 srtK; sensor protein\tK20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK\/SpaK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0779 srtR; two-component response regulator\tK20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR\/SpaR"
				},
				{
					"name":"M28_Spy0785 srtF; lantibiotic transport ATP-binding protein\tK20490 nisF; lantibiotic transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0786 srtE; lantibiotic transport permease protein\tK20491 nisE; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0787 srtG; lantibiotic transport permease protein\tK20492 nisG; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0421 long-chain-fatty-acid--CoA ligase"
				}
				]
			},
			{
				"name":"05111 Biofilm formation - Vibrio cholerae"
			},
			{
				"name":"02025 Biofilm formation - Pseudomonas aeruginosa"
			},
			{
				"name":"02026 Biofilm formation - Escherichia coli"
			}
			]
		},
		{
			"name":"09142 Cell motility",
			"children":[
			{
				"name":"02030 Bacterial chemotaxis"
			},
			{
				"name":"02040 Flagellar assembly [PATH:spb02040]",
				"children":[
				{
					"name":"M28_Spy0262 ABC transporter substrate-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0686 cystine-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0579 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor"
				}
				]
			},
			{
				"name":"04814 Motor proteins"
			},
			{
				"name":"04820 Cytoskeleton in muscle cells",
				"children":[
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				}
				]
			},
			{
				"name":"04810 Regulation of actin cytoskeleton"
			}
			]
		}
		]
	},
	{
		"name":"09150 Organismal Systems",
		"children":[
		{
			"name":"09151 Immune system",
			"children":[
			{
				"name":"04640 Hematopoietic cell lineage"
			},
			{
				"name":"04610 Complement and coagulation cascades"
			},
			{
				"name":"04611 Platelet activation"
			},
			{
				"name":"04613 Neutrophil extracellular trap formation"
			},
			{
				"name":"04620 Toll-like receptor signaling pathway"
			},
			{
				"name":"04624 Toll and Imd signaling pathway"
			},
			{
				"name":"04621 NOD-like receptor signaling pathway"
			},
			{
				"name":"04622 RIG-I-like receptor signaling pathway"
			},
			{
				"name":"04623 Cytosolic DNA-sensing pathway"
			},
			{
				"name":"04625 C-type lectin receptor signaling pathway"
			},
			{
				"name":"04650 Natural killer cell mediated cytotoxicity"
			},
			{
				"name":"04612 Antigen processing and presentation"
			},
			{
				"name":"04660 T cell receptor signaling pathway"
			},
			{
				"name":"04658 Th1 and Th2 cell differentiation"
			},
			{
				"name":"04659 Th17 cell differentiation"
			},
			{
				"name":"04657 IL-17 signaling pathway"
			},
			{
				"name":"04662 B cell receptor signaling pathway"
			},
			{
				"name":"04664 Fc epsilon RI signaling pathway"
			},
			{
				"name":"04666 Fc gamma R-mediated phagosome formation"
			},
			{
				"name":"04670 Leukocyte transendothelial migration"
			},
			{
				"name":"04672 Intestinal immune network for IgA production"
			},
			{
				"name":"04062 Chemokine signaling pathway"
			}
			]
		},
		{
			"name":"09152 Endocrine system",
			"children":[
			{
				"name":"04911 Insulin secretion"
			},
			{
				"name":"04910 Insulin signaling pathway"
			},
			{
				"name":"04922 Glucagon signaling pathway"
			},
			{
				"name":"04923 Regulation of lipolysis in adipocytes"
			},
			{
				"name":"04920 Adipocytokine signaling pathway"
			},
			{
				"name":"03320 PPAR signaling pathway"
			},
			{
				"name":"04929 GnRH secretion"
			},
			{
				"name":"04912 GnRH signaling pathway"
			},
			{
				"name":"04913 Ovarian steroidogenesis"
			},
			{
				"name":"04915 Estrogen signaling pathway"
			},
			{
				"name":"04914 Progesterone-mediated oocyte maturation"
			},
			{
				"name":"04917 Prolactin signaling pathway"
			},
			{
				"name":"04921 Oxytocin signaling pathway"
			},
			{
				"name":"04926 Relaxin signaling pathway"
			},
			{
				"name":"04935 Growth hormone synthesis, secretion and action"
			},
			{
				"name":"04918 Thyroid hormone synthesis"
			},
			{
				"name":"04919 Thyroid hormone signaling pathway"
			},
			{
				"name":"04928 Parathyroid hormone synthesis, secretion and action"
			},
			{
				"name":"04916 Melanogenesis"
			},
			{
				"name":"04924 Renin secretion"
			},
			{
				"name":"04614 Renin-angiotensin system"
			},
			{
				"name":"04925 Aldosterone synthesis and secretion"
			},
			{
				"name":"04927 Cortisol synthesis and secretion"
			}
			]
		},
		{
			"name":"09153 Circulatory system",
			"children":[
			{
				"name":"04260 Cardiac muscle contraction"
			},
			{
				"name":"04261 Adrenergic signaling in cardiomyocytes"
			},
			{
				"name":"04270 Vascular smooth muscle contraction"
			}
			]
		},
		{
			"name":"09154 Digestive system",
			"children":[
			{
				"name":"04970 Salivary secretion"
			},
			{
				"name":"04971 Gastric acid secretion"
			},
			{
				"name":"04972 Pancreatic secretion"
			},
			{
				"name":"04976 Bile secretion"
			},
			{
				"name":"04973 Carbohydrate digestion and absorption"
			},
			{
				"name":"04974 Protein digestion and absorption"
			},
			{
				"name":"04975 Fat digestion and absorption"
			},
			{
				"name":"04979 Cholesterol metabolism"
			},
			{
				"name":"04977 Vitamin digestion and absorption"
			},
			{
				"name":"04981 Folate transport and metabolism [PATH:spb04981]",
				"children":[
				{
					"name":"M28_Spy0669 dyr; dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"M28_Spy0841 glyA; serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"M28_Spy0668 thyA; thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				}
				]
			},
			{
				"name":"04980 Cobalamin transport and metabolism"
			},
			{
				"name":"04978 Mineral absorption"
			}
			]
		},
		{
			"name":"09155 Excretory system",
			"children":[
			{
				"name":"04962 Vasopressin-regulated water reabsorption"
			},
			{
				"name":"04960 Aldosterone-regulated sodium reabsorption"
			},
			{
				"name":"04961 Endocrine and other factor-regulated calcium reabsorption"
			},
			{
				"name":"04964 Proximal tubule bicarbonate reclamation"
			},
			{
				"name":"04966 Collecting duct acid secretion"
			}
			]
		},
		{
			"name":"09156 Nervous system",
			"children":[
			{
				"name":"04724 Glutamatergic synapse"
			},
			{
				"name":"04727 GABAergic synapse"
			},
			{
				"name":"04725 Cholinergic synapse"
			},
			{
				"name":"04728 Dopaminergic synapse"
			},
			{
				"name":"04726 Serotonergic synapse"
			},
			{
				"name":"04720 Long-term potentiation"
			},
			{
				"name":"04730 Long-term depression"
			},
			{
				"name":"04723 Retrograde endocannabinoid signaling"
			},
			{
				"name":"04721 Synaptic vesicle cycle"
			},
			{
				"name":"04722 Neurotrophin signaling pathway"
			}
			]
		},
		{
			"name":"09157 Sensory system",
			"children":[
			{
				"name":"04744 Phototransduction"
			},
			{
				"name":"04745 Phototransduction - fly"
			},
			{
				"name":"04740 Olfactory transduction"
			},
			{
				"name":"04742 Taste transduction"
			},
			{
				"name":"04750 Inflammatory mediator regulation of TRP channels"
			}
			]
		},
		{
			"name":"09158 Development and regeneration",
			"children":[
			{
				"name":"04320 Dorso-ventral axis formation"
			},
			{
				"name":"04360 Axon guidance"
			},
			{
				"name":"04361 Axon regeneration"
			},
			{
				"name":"04380 Osteoclast differentiation"
			},
			{
				"name":"04382 Cornified envelope formation [PATH:spb04382]",
				"children":[
				{
					"name":"M28_Spy1397 pepC; aminopeptidase C\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"M28_Spy1761 hutH; histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				}
				]
			}
			]
		},
		{
			"name":"09149 Aging",
			"children":[
			{
				"name":"04211 Longevity regulating pathway"
			},
			{
				"name":"04212 Longevity regulating pathway - worm"
			},
			{
				"name":"04213 Longevity regulating pathway - multiple species"
			}
			]
		},
		{
			"name":"09159 Environmental adaptation",
			"children":[
			{
				"name":"04710 Circadian rhythm"
			},
			{
				"name":"04713 Circadian entrainment"
			},
			{
				"name":"04711 Circadian rhythm - fly"
			},
			{
				"name":"04712 Circadian rhythm - plant"
			},
			{
				"name":"04714 Thermogenesis"
			},
			{
				"name":"04626 Plant-pathogen interaction"
			}
			]
		}
		]
	},
	{
		"name":"09160 Human Diseases",
		"children":[
		{
			"name":"09161 Cancer: overview",
			"children":[
			{
				"name":"05200 Pathways in cancer"
			},
			{
				"name":"05202 Transcriptional misregulation in cancer"
			},
			{
				"name":"05206 MicroRNAs in cancer"
			},
			{
				"name":"05205 Proteoglycans in cancer"
			},
			{
				"name":"05204 Chemical carcinogenesis - DNA adducts"
			},
			{
				"name":"05207 Chemical carcinogenesis - receptor activation"
			},
			{
				"name":"05208 Chemical carcinogenesis - reactive oxygen species"
			},
			{
				"name":"05203 Viral carcinogenesis"
			},
			{
				"name":"05230 Central carbon metabolism in cancer"
			},
			{
				"name":"05231 Choline metabolism in cancer"
			},
			{
				"name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer"
			}
			]
		},
		{
			"name":"09162 Cancer: specific types",
			"children":[
			{
				"name":"05210 Colorectal cancer"
			},
			{
				"name":"05212 Pancreatic cancer"
			},
			{
				"name":"05225 Hepatocellular carcinoma"
			},
			{
				"name":"05226 Gastric cancer"
			},
			{
				"name":"05214 Glioma"
			},
			{
				"name":"05216 Thyroid cancer"
			},
			{
				"name":"05221 Acute myeloid leukemia"
			},
			{
				"name":"05220 Chronic myeloid leukemia"
			},
			{
				"name":"05217 Basal cell carcinoma"
			},
			{
				"name":"05218 Melanoma"
			},
			{
				"name":"05211 Renal cell carcinoma"
			},
			{
				"name":"05219 Bladder cancer"
			},
			{
				"name":"05215 Prostate cancer"
			},
			{
				"name":"05213 Endometrial cancer"
			},
			{
				"name":"05224 Breast cancer"
			},
			{
				"name":"05222 Small cell lung cancer"
			},
			{
				"name":"05223 Non-small cell lung cancer"
			}
			]
		},
		{
			"name":"09172 Infectious disease: viral",
			"children":[
			{
				"name":"05166 Human T-cell leukemia virus 1 infection"
			},
			{
				"name":"05170 Human immunodeficiency virus 1 infection"
			},
			{
				"name":"05161 Hepatitis B"
			},
			{
				"name":"05160 Hepatitis C"
			},
			{
				"name":"05171 Coronavirus disease"
			},
			{
				"name":"05164 Influenza A"
			},
			{
				"name":"05162 Measles"
			},
			{
				"name":"05168 Herpes simplex virus 1 infection"
			},
			{
				"name":"05163 Human cytomegalovirus infection"
			},
			{
				"name":"05167 Kaposi sarcoma-associated herpesvirus infection"
			},
			{
				"name":"05169 Epstein-Barr virus infection"
			},
			{
				"name":"05165 Human papillomavirus infection"
			}
			]
		},
		{
			"name":"09171 Infectious disease: bacterial",
			"children":[
			{
				"name":"05110 Vibrio cholerae infection"
			},
			{
				"name":"05120 Epithelial cell signaling in Helicobacter pylori infection"
			},
			{
				"name":"05130 Pathogenic Escherichia coli infection"
			},
			{
				"name":"05132 Salmonella infection"
			},
			{
				"name":"05131 Shigellosis"
			},
			{
				"name":"05135 Yersinia infection"
			},
			{
				"name":"05133 Pertussis"
			},
			{
				"name":"05134 Legionellosis"
			},
			{
				"name":"05150 Staphylococcus aureus infection"
			},
			{
				"name":"05152 Tuberculosis"
			},
			{
				"name":"05100 Bacterial invasion of epithelial cells",
				"children":[
				{
					"name":"M28_Spy0105 sfb1; fibronectin binding protein 1\tK13734 sfb1; fibronectin-binding protein 1"
				},
				{
					"name":"M28_Spy0107 cpa; collagen-binding protein Cpa, pilus ancillary protein 1\tK13734 sfb1; fibronectin-binding protein 1"
				},
				{
					"name":"M28_Spy1715 sfbX; fibronectin-binding protein\tK13734 sfb1; fibronectin-binding protein 1"
				}
				]
			}
			]
		},
		{
			"name":"09174 Infectious disease: parasitic",
			"children":[
			{
				"name":"05146 Amoebiasis"
			},
			{
				"name":"05144 Malaria"
			},
			{
				"name":"05145 Toxoplasmosis"
			},
			{
				"name":"05140 Leishmaniasis"
			},
			{
				"name":"05142 Chagas disease"
			},
			{
				"name":"05143 African trypanosomiasis"
			}
			]
		},
		{
			"name":"09163 Immune disease",
			"children":[
			{
				"name":"05310 Asthma"
			},
			{
				"name":"05322 Systemic lupus erythematosus"
			},
			{
				"name":"05323 Rheumatoid arthritis"
			},
			{
				"name":"05320 Autoimmune thyroid disease"
			},
			{
				"name":"05321 Inflammatory bowel disease"
			},
			{
				"name":"05330 Allograft rejection"
			},
			{
				"name":"05332 Graft-versus-host disease"
			},
			{
				"name":"05340 Primary immunodeficiency"
			}
			]
		},
		{
			"name":"09164 Neurodegenerative disease",
			"children":[
			{
				"name":"05010 Alzheimer disease"
			},
			{
				"name":"05012 Parkinson disease"
			},
			{
				"name":"05014 Amyotrophic lateral sclerosis"
			},
			{
				"name":"05016 Huntington disease"
			},
			{
				"name":"05017 Spinocerebellar ataxia"
			},
			{
				"name":"05020 Prion disease"
			},
			{
				"name":"05022 Pathways of neurodegeneration - multiple diseases"
			}
			]
		},
		{
			"name":"09165 Substance dependence",
			"children":[
			{
				"name":"05030 Cocaine addiction"
			},
			{
				"name":"05031 Amphetamine addiction"
			},
			{
				"name":"05032 Morphine addiction"
			},
			{
				"name":"05033 Nicotine addiction"
			},
			{
				"name":"05034 Alcoholism"
			}
			]
		},
		{
			"name":"09166 Cardiovascular disease",
			"children":[
			{
				"name":"05417 Lipid and atherosclerosis"
			},
			{
				"name":"05418 Fluid shear stress and atherosclerosis"
			},
			{
				"name":"05410 Hypertrophic cardiomyopathy"
			},
			{
				"name":"05412 Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"05414 Dilated cardiomyopathy"
			},
			{
				"name":"05415 Diabetic cardiomyopathy"
			},
			{
				"name":"05416 Viral myocarditis"
			}
			]
		},
		{
			"name":"09167 Endocrine and metabolic disease",
			"children":[
			{
				"name":"04930 Type II diabetes mellitus"
			},
			{
				"name":"04940 Type I diabetes mellitus"
			},
			{
				"name":"04950 Maturity onset diabetes of the young"
			},
			{
				"name":"04936 Alcoholic liver disease"
			},
			{
				"name":"04932 Non-alcoholic fatty liver disease"
			},
			{
				"name":"04931 Insulin resistance"
			},
			{
				"name":"04933 AGE-RAGE signaling pathway in diabetic complications"
			},
			{
				"name":"04934 Cushing syndrome"
			}
			]
		},
		{
			"name":"09175 Drug resistance: antimicrobial",
			"children":[
			{
				"name":"01501 beta-Lactam resistance [PATH:spb01501]",
				"children":[
				{
					"name":"M28_Spy0010 hypothetical protein\tK01467 ampC; beta-lactamase class C [EC:3.5.2.6]"
				},
				{
					"name":"M28_Spy0244 oppA; oligopeptide-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0245 oppB; oligopeptide transport system permease protein\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0246 oppC; oligopeptide transport system permease protein\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0247 oppD; oligopeptide transport ATP-binding protein\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0248 oppF; oligopeptide transport ATP-binding protein\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B\tK03693 pbp1b; penicillin-binding protein 1B"
				},
				{
					"name":"M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase\tK12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy1408 division specific D,D-transpeptidase\tK12556 pbp2X; penicillin-binding protein 2X"
				}
				]
			},
			{
				"name":"01502 Vancomycin resistance [PATH:spb01502]",
				"children":[
				{
					"name":"M28_Spy1152 ddlA; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"M28_Spy1522 acpS; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
				},
				{
					"name":"M28_Spy1151 murF; UDP-N-acetylmuramoylalanine-D-glutamyl-lysine--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				}
				]
			},
			{
				"name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:spb01503]",
				"children":[
				{
					"name":"M28_Spy1898 htrA; protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"M28_Spy0360 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1054 dltA; D-alanine-activating enzyme\tK03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1053 DltB\tK03739 dltB; membrane protein involved in D-alanine export"
				},
				{
					"name":"M28_Spy1052 D-alanyl carrier protein\tK14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1051 dltD; protein precursor\tK03740 dltD; D-alanine transfer protein"
				},
				{
					"name":"M28_Spy1721 speB; pyrogenic exotoxin B\tK01364 speB; streptopain [EC:3.4.22.10]"
				}
				]
			}
			]
		},
		{
			"name":"09176 Drug resistance: antineoplastic",
			"children":[
			{
				"name":"01521 EGFR tyrosine kinase inhibitor resistance"
			},
			{
				"name":"01524 Platinum drug resistance"
			},
			{
				"name":"01523 Antifolate resistance"
			},
			{
				"name":"01522 Endocrine resistance"
			}
			]
		}
		]
	},
	{
		"name":"09180 Brite Hierarchies",
		"children":[
		{
			"name":"09181 Protein families: metabolism",
			"children":[
			{
				"name":"01000 Enzymes [BR:spb01000]"
			},
			{
				"name":"01001 Protein kinases [BR:spb01001]",
				"children":[
				{
					"name":"M28_Spy1376 serine\/threonine protein kinase\tK12132 prkC; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"M28_Spy0424 vicK; two-component sensor histidine kinase\tK07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0919 ciaH; sensor protein\tK14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0275 covS; CsrS\tK18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1708 ihk; two component system histidine kinase\tK18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0780 srtK; sensor protein\tK20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK\/SpaK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1374 yvqE; two-component sensor protein\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1616 sensory transduction protein kinase\tK14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK"
				},
				{
					"name":"M28_Spy0808 dpiB; sensor kinase\tK02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0198 fasB; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0199 fasC; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1359 rocA; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1218 yesM; two-component system sensor kinase YesM\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1347 two-component sensor kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"01009 Protein phosphatases and associated proteins [BR:spb01009]",
				"children":[
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy1377 pppL; protein phosphatase 2C\tK20074 prpC; PPM family protein phosphatase [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"01002 Peptidases and inhibitors [BR:spb01002]",
				"children":[
				{
					"name":"M28_Spy0617 lsp; lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"M28_Spy1397 pepC; aminopeptidase C\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"M28_Spy1721 speB; pyrogenic exotoxin B\tK01364 speB; streptopain [EC:3.4.22.10]"
				},
				{
					"name":"M28_Spy0405 pcp; pyrrolidone-carboxylate peptidase\tK01304 PGPEP1; pyroglutamyl-peptidase [EC:3.4.19.3]"
				},
				{
					"name":"M28_Spy0891 guaA; glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"M28_Spy0817 glutamine amidotransferase, class I\tK07010 K07010; putative glutamine amidotransferase"
				},
				{
					"name":"M28_Spy0017 sibA; secreted protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy1703 mrp; emm related protein Mrp\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy0024 purF; amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"M28_Spy0958 glmS; isomerizing glucosamine--fructose-6-phosphate aminotransferase\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"M28_Spy0849 sortase\tK07284 srtA; sortase A [EC:3.4.22.70]"
				},
				{
					"name":"M28_Spy0110 srtB; class B sortase protein SrtB\tK08600 srtB; sortase B [EC:3.4.22.71]"
				},
				{
					"name":"M28_Spy0520 pepD; dipeptidase\tK08659 pepDA; dipeptidase [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy0544 sagE; streptolysin S putative self-immunity protein\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"M28_Spy1123 CaaX amino terminal protease family\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"M28_Spy0921 pepN; lysyl aminopeptidase\tK01256 pepN; aminopeptidase N [EC:3.4.11.2]"
				},
				{
					"name":"M28_Spy1130 pepB; oligoendopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy1766 pepO; neutral endopeptidase\tK07386 pepO; putative endopeptidase [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				},
				{
					"name":"M28_Spy0767 Xaa-His dipeptidase\tK01274 pepV; beta-Ala-Xaa dipeptidase [EC:3.4.13.-]"
				},
				{
					"name":"M28_Spy0593 pepT; peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
				},
				{
					"name":"M28_Spy1095 map; methionine aminopeptidase\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"M28_Spy1536 Xaa-Pro dipeptidase\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
				},
				{
					"name":"M28_Spy0013 ftsH; cell division protein\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy0095 pepA; glutamyl aminopeptidase\tK01261 pepA; glutamyl aminopeptidase [EC:3.4.11.7]"
				},
				{
					"name":"M28_Spy0272 heat shock protein HtpX\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy1662 pheromone-processing membrane metalloprotease\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy1898 htrA; protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"M28_Spy1700 scpA; C5A peptidase precursor\tK08652 C5AP; C5a peptidase [EC:3.4.21.110]"
				},
				{
					"name":"M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy0317 clpP; ATP-dependent Clp protease proteolytic subunit\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"M28_Spy1565 pepXP; Xaa-Pro dipeptidyl-peptidase\tK01281 pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]"
				},
				{
					"name":"M28_Spy1204 ATP-dependent protease La\tK07177 K07177; Lon-like protease"
				},
				{
					"name":"M28_Spy0108 sipA; signal peptidase I protein SipA\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy0959 sipC; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy1553 spi; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"M28_Spy0471 peptidase family U32\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
				}
				]
			},
			{
				"name":"01003 Glycosyltransferases [BR:spb01003]",
				"children":[
				{
					"name":"M28_Spy0414 1,2-diacylglycerol 3-glucosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				},
				{
					"name":"M28_Spy0413 glycosyltransferase\tK13677 dgs; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]"
				},
				{
					"name":"M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B\tK03693 pbp1b; penicillin-binding protein 1B"
				},
				{
					"name":"M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase\tK12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy0485 ftsW; cell division protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"01005 Lipopolysaccharide biosynthesis proteins [BR:spb01005]",
				"children":[
				{
					"name":"M28_Spy0582 rgpAc; alpha-(1,2)-rhamnosyltransferase\tK12996 rgpA; rhamnosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"M28_Spy0583 rgpBc; alpha-L-Rha alpha-1,3-L-rhamnosyltransferase\tK12997 rgpB; rhamnosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"M28_Spy0586 rgpEc; glycosyltransferase\tK12998 rgpE; glucosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"M28_Spy0587 rgpFc; alpha-L-Rha alpha-1,2-L-rhamnosyltransferase\tK07272 rgpF; rhamnosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"M28_Spy0235 undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"M28_Spy0408 glucosyltransferase\tK12999 rgpI; glucosyltransferase [EC:2.4.1.-]"
				}
				]
			},
			{
				"name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:spb01011]",
				"children":[
				{
					"name":"M28_Spy0562 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy1099 murZ; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"M28_Spy0802 murB; UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"M28_Spy0282 murC; UDP-N-acetylmuramate--alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"M28_Spy1192 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"M28_Spy0314 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--lysine ligase\tK05362 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]"
				},
				{
					"name":"M28_Spy1152 ddlA; D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"M28_Spy0490 murM; UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase\tK05363 murM; serine\/alanine adding enzyme [EC:2.3.2.10]"
				},
				{
					"name":"M28_Spy0892 UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase\tK05363 murM; serine\/alanine adding enzyme [EC:2.3.2.10]"
				},
				{
					"name":"M28_Spy0489 methicillin resistance expression factor\tK12554 murN; alanine adding enzyme [EC:2.3.2.-]"
				},
				{
					"name":"M28_Spy1522 acpS; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
				},
				{
					"name":"M28_Spy0292 glr; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"M28_Spy1407 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"M28_Spy1191 murG; UDP-GlcNAc--MurNAc-(pentapeptide) pyrophosphoryl-undecaprenol GlcNAc transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"M28_Spy0233 bacA; putative undecaprenol kinase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"M28_Spy1396 pbp1A; multimodular transpeptidase-transglycosylase\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy0080 pbp1b; multimodular transpeptidase-transglycosylase PBP 1B\tK03693 pbp1b; penicillin-binding protein 1B"
				},
				{
					"name":"M28_Spy1739 pbp2A; multimodular transpeptidase-transglycosylase\tK12555 pbp2A; penicillin-binding protein 2A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"M28_Spy1408 division specific D,D-transpeptidase\tK12556 pbp2X; penicillin-binding protein 2X"
				},
				{
					"name":"M28_Spy0243 dacA2; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy0794 dacA1; D-alanyl-D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy0485 ftsW; cell division protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				},
				{
					"name":"M28_Spy0017 sibA; secreted protein\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy1703 mrp; emm related protein Mrp\tK21471 cwlO; peptidoglycan DL-endopeptidase CwlO [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy0849 sortase\tK07284 srtA; sortase A [EC:3.4.22.70]"
				},
				{
					"name":"M28_Spy0110 srtB; class B sortase protein SrtB\tK08600 srtB; sortase B [EC:3.4.22.71]"
				},
				{
					"name":"M28_Spy0284 aminodeoxychorismate lyase family\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
				}
				]
			},
			{
				"name":"01004 Lipid biosynthesis proteins [BR:spb01004]",
				"children":[
				{
					"name":"M28_Spy1480 fabD; malonyl-CoA-[acyl-carrier-protein] transacylase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"M28_Spy1483 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"M28_Spy1478 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"M28_Spy0348 short chain dehydrogenase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1479 3-oxoacyl-[acyl-carrier protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"M28_Spy1476 fabZ; (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase\tK02372 fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
				},
				{
					"name":"M28_Spy1481 fabK; enoyl-[acyl-carrier protein] reductase (NADH)\tK02371 fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]"
				},
				{
					"name":"M28_Spy1485 phaB; enoyl-CoA hydratase\tK18474 fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]"
				},
				{
					"name":"M28_Spy0020 plsX; fatty acid\/phospholipid synthesis protein\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"M28_Spy0690 putative membrane spanning protein\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"M28_Spy1145 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				}
				]
			},
			{
				"name":"01008 Polyketide biosynthesis proteins"
			},
			{
				"name":"01006 Prenyltransferases [BR:spb01006]",
				"children":[
				{
					"name":"M28_Spy1170 fps; dimethylallyltransferase\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"M28_Spy1664 uppS; undecaprenyl pyrophosphate synthetase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"M28_Spy0702 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				}
				]
			},
			{
				"name":"01007 Amino acid related enzymes [BR:spb01007]",
				"children":[
				{
					"name":"M28_Spy0197 gltX; glutamyl-tRNA synthetase\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				},
				{
					"name":"M28_Spy0079 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"M28_Spy1891 trsA; tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"M28_Spy1643 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"M28_Spy1817 argS; arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"M28_Spy0332 metS; methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"M28_Spy1182 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"M28_Spy1296 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"M28_Spy0145 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"M28_Spy0474 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"M28_Spy1822 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"M28_Spy0516 asnS; asnS\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"M28_Spy1823 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy1472 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"M28_Spy1661 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"M28_Spy0415 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"M28_Spy1126 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy1502 aspartate aminotransferase\tK14260 alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]"
				},
				{
					"name":"M28_Spy0693 bcaT; branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"M28_Spy1682 para-aminobenzoate synthetase component I\tK03342 pabBC; para-aminobenzoate synthetase \/ 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]"
				}
				]
			},
			{
				"name":"00199 Cytochrome P450"
			},
			{
				"name":"00194 Photosynthesis proteins [BR:spb00194]",
				"children":[
				{
					"name":"M28_Spy0560 atpC; ATP synthase epsilon chain\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"M28_Spy0559 atpD; ATPase, beta subunit\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"M28_Spy0558 atpG; ATP synthase gamma chain\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"M28_Spy0557 atpA; ATP synthase alpha chain\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"M28_Spy0556 atpH; ATP synthase delta chain\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"M28_Spy0555 atpF; ATP synthase B chain\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"M28_Spy0553 atpE; ATP synthase C chain\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"M28_Spy0554 atpB; ATP synthase A chain\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				}
				]
			}
			]
		},
		{
			"name":"09182 Protein families: genetic information processing",
			"children":[
			{
				"name":"03000 Transcription factors [BR:spb03000]",
				"children":[
				{
					"name":"M28_Spy0774 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"M28_Spy1445 lacR.1; lactose phosphotransferase system repressor\tK02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor"
				},
				{
					"name":"M28_Spy1629 lacR.2; lactose phosphotransferase system repressor\tK02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor"
				},
				{
					"name":"M28_Spy0641 fruR; fructose repressor\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"M28_Spy0412 ccpA; catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"M28_Spy1038 malR; transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"M28_Spy1203 ribose operon repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"M28_Spy0496 regR; transcriptional regulator, LacI family\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				},
				{
					"name":"M28_Spy1531 scrR; sucrose operon repressor\tK03484 scrR; LacI family transcriptional regulator, sucrose operon repressor"
				},
				{
					"name":"M28_Spy1356 transcriptional regulator, GntR family\tK02103 araR; GntR family transcriptional regulator, arabinose operon transcriptional repressor"
				},
				{
					"name":"M28_Spy1769 trehalose operon transcriptional repressor\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"M28_Spy0522 transcriptional regulator, GntR family\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"M28_Spy0889 transcriptional regulator, GntR family\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"M28_Spy1589 transcriptional regulator, MerR family\tK03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor"
				},
				{
					"name":"M28_Spy0159 perR; ferric uptake regulation protein\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				},
				{
					"name":"M28_Spy1214 transcription regulator, crp family\tK21828 arcR; CRP\/FNR family transcriptional regulator, arginine deiminase pathway regulator"
				},
				{
					"name":"M28_Spy1827 cadC; cadmium efflux system accessory protein\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"M28_Spy1835 transcriptional regulator, PadR family\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"M28_Spy0356 scaR; iron-dependent repressor\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"M28_Spy1102 birA; biotin operon repressor\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"M28_Spy0034 comR; competence transcriptional regulator ComR\tK20342 comR; HTH-type transcriptional regulator, regulator for ComX"
				},
				{
					"name":"M28_Spy0395 mutR; transcriptional regulator\tK20373 rgg2; HTH-type transcriptional regulator, SHP2-responsive activator"
				},
				{
					"name":"M28_Spy0428 transcriptional regulator\tK20374 rgg3; HTH-type transcriptional regulator, SHP3-responsive repressor"
				},
				{
					"name":"M28_Spy1724 rgg; transcriptional regulator\tK20375 ropB; HTH-type transcriptional regulator, pheromone-responsive regulator"
				},
				{
					"name":"M28_Spy0222 purR; pur operon repressor\tK09685 purR; HTH-type transcriptional regulator, purine operon repressor"
				},
				{
					"name":"M28_Spy0818 redox-sensitive transcriptional regulator Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"M28_Spy1501 codY; transcription pleiotropic repressor\tK03706 codY; transcriptional pleiotropic repressor"
				},
				{
					"name":"M28_Spy1793 phage transcriptional repressor\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"M28_Spy1021 phage protein\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"M28_Spy1125 transcriptional regulator, Cro\/CI family\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"M28_Spy1636 transcriptional regulator, Cro\/CI family\tK07729 K07729; putative transcriptional regulator"
				},
				{
					"name":"M28_Spy0455 licT; transcription antiterminator, BglG family\tK03488 licT; beta-glucoside operon transcriptional antiterminator"
				},
				{
					"name":"M28_Spy0153 transcription antiterminator, BglG family\tK03493 bglG1; transcriptional antiterminator"
				},
				{
					"name":"M28_Spy1064 transcription antiterminator, BglG family\tK03491 licR; probable licABCH operon transcriptional regulator"
				},
				{
					"name":"M28_Spy1255 ParB-like protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"M28_Spy1899 parB; chromosome partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"M28_Spy1168 argR1; arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"M28_Spy1215 ahrC.2; arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"M28_Spy1816 argR2; arginine repressor\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"M28_Spy1489 hrcA; heat-inducible transcription repressor\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"M28_Spy1750 ctsR; transcriptional regulator\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"M28_Spy0619 pyrR; bifunctional pyrimidine regulatory protein PyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"M28_Spy0276 putative regulatory protein\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"M28_Spy0251 comX; competence-specific sigma factor ComX\tK12296 comX1_2; competence protein ComX"
				},
				{
					"name":"M28_Spy1607 comX.2; competence-specific sigma factor\tK12296 comX1_2; competence protein ComX"
				}
				]
			},
			{
				"name":"03021 Transcription machinery [BR:spb03021]",
				"children":[
				{
					"name":"M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain\tK03048 rpoE; DNA-directed RNA polymerase subunit delta"
				},
				{
					"name":"M28_Spy1381 DNA-directed RNA polymerase omega chain\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0579 rpoD; RNA polymerase sigma factor\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"M28_Spy1455 nusA; N utilization substance protein A\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"M28_Spy1532 nusB; N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"M28_Spy0136 nusG; transcription antitermination protein\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"M28_Spy0285 greA; transcription elongation factor\tK03624 greA; transcription elongation factor GreA"
				}
				]
			},
			{
				"name":"03019 Messenger RNA biogenesis [BR:spb03019]",
				"children":[
				{
					"name":"M28_Spy0426 acpA; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"M28_Spy0726 Zn-dependent hydrolase\tK12574 rnj; ribonuclease J [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy1587 Zn-dependent hydrolase\tK12574 rnj; ribonuclease J [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy1383 hydrolase (HAD superfamily)\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0402 exoribonuclease II\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"M28_Spy0221 cbf; CMP-binding factor\tK03698 cbf; 3'-5' exoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy1148 deaD; ATP-dependent RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"M28_Spy1406 ATP-dependent RNA helicase\tK18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]"
				},
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"M28_Spy1648 polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"M28_Spy0961 pfk; non-allosteric 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"M28_Spy0517 ATP-binding protein\tK06958 rapZ; RNase adapter protein RapZ"
				}
				]
			},
			{
				"name":"03041 Spliceosome"
			},
			{
				"name":"03011 Ribosome [BR:spb03011]",
				"children":[
				{
					"name":"M28_Spy0695 SSU ribosomal protein S1P\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"M28_Spy1764 rpsB; SSU ribosomal protein S2P\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"M28_Spy0049 rpsC; SSU ribosomal protein S3P\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"M28_Spy1865 rpsD; SSU ribosomal protein S4P\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"M28_Spy0060 rpsE; SSU ribosomal protein S5P\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"M28_Spy1542 rpsF; SSU ribosomal protein S6P\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"M28_Spy0225 rpsG; SSU ribosomal protein S7P\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"M28_Spy0057 rpsH; SSU ribosomal protein S8P\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"M28_Spy1634 rpsI; SSU ribosomal protein S9P\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"M28_Spy0042 rpsJ; SSU ribosomal protein S10P\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"M28_Spy0068 rpsK; SSU ribosomal protein S11P\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"M28_Spy0224 rpsL; SSU ribosomal protein S12P\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"M28_Spy0067 rpsM; SSU ribosomal protein S13P\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"M28_Spy0056 rpsN; SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"M28_Spy1582 rpsN2; SSU ribosomal protein S14P\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"M28_Spy1654 SSU ribosomal protein S15P\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"M28_Spy0629 rpsP; SSU ribosomal protein S16P\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"M28_Spy0052 rpsQ; SSU ribosomal protein S17P\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"M28_Spy1540 rpsR; SSU ribosomal protein S18P\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"M28_Spy0047 rpsS; SSU ribosomal protein S19P\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"M28_Spy0918 rpsT; SSU ribosomal protein S20P\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"M28_Spy0576 SSU ribosomal protein S21P\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"M28_Spy0364 rplA; LSU ribosomal protein L1P\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"M28_Spy0046 rplB; LSU ribosomal protein L2P\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"M28_Spy0043 rplC; LSU ribosomal protein L3P\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"M28_Spy0044 rplD; LSU ribosomal protein L1E\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"M28_Spy0055 rplE; LSU ribosomal protein L5P\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"M28_Spy0058 rplF; LSU ribosomal protein L6P\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"M28_Spy1868 rplI; LSU ribosomal protein L9P\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"M28_Spy0769 rplJ; LSU ribosomal protein L10P\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"M28_Spy0363 rplK; LSU ribosomal protein L11P\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"M28_Spy0770 rplL; LSU ribosomal protein L7\/L12P\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"M28_Spy1635 rplM; LSU ribosomal protein L13P\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"M28_Spy0053 rplN; LSU ribosomal protein L14P\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"M28_Spy0062 rplO; LSU ribosomal protein L15P\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"M28_Spy0050 rplP; LSU ribosomal protein L16P\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"M28_Spy0070 rplQ; LSU ribosomal protein L17P\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"M28_Spy0059 rplR; LSU ribosomal protein L18P\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"M28_Spy0529 rplS; LSU ribosomal protein L19P\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"M28_Spy0600 rplT; LSU ribosomal protein L20P\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"M28_Spy0613 rplU; LSU ribosomal protein L21P\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"M28_Spy0048 rplV; LSU ribosomal protein L22P\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"M28_Spy0045 rplW; LSU ribosomal protein L23P\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"M28_Spy0054 rplX; LSU ribosomal protein L24P\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"M28_Spy0615 rpmA; LSU ribosomal protein L27P\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"M28_Spy1596 rpmB; LSU ribosomal protein L28P\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"M28_Spy0051 rpmC; LSU ribosomal protein L29P\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"M28_Spy0061 rpmD; LSU ribosomal protein L30P\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"M28_Spy0524 rpmE; LSU ribosomal protein L31P\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"M28_Spy1824 rpmF; LSU ribosomal protein L32P\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"M28_Spy0400 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy1738 LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy1825 rpmG; LSU ribosomal protein L33P\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"M28_Spy0205 rpmH; LSU ribosomal protein L34P\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"M28_Spy0599 rpl36; LSU ribosomal protein L35P\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"M28_Spy0066 rpmJ; LSU ribosomal protein L36P\tK02919 RP-L36; large subunit ribosomal protein L36"
				},
				{
					"name":"M28_SpyR0001 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0004 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0007 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0010 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0018 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0002 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0005 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0008 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0011 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0014 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0017 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0003 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0009 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0013 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0016 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				}
				]
			},
			{
				"name":"03009 Ribosome biogenesis [BR:spb03009]",
				"children":[
				{
					"name":"M28_Spy0426 acpA; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"M28_Spy0376 era; putative GTP-binding protein\tK03595 era; GTPase"
				},
				{
					"name":"M28_Spy1069 obg; GTP-binding protein OBG family\tK03979 obgE; GTPase [EC:3.6.5.-]"
				},
				{
					"name":"M28_Spy1455 nusA; N utilization substance protein A\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"M28_Spy1532 nusB; N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"M28_Spy0136 nusG; transcription antitermination protein\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"M28_Spy1073 rsuA; ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"M28_Spy1132 ribosomal small subunit pseudouridine synthase A\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"M28_Spy0216 ksgA; dimethyladenosine transferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"M28_Spy1378 sunL; 16S rRNA m(5)C 967 methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"M28_Spy0916 16S rRNA m(2)G 1207 methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"M28_Spy1206 methyltransferase\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"M28_Spy1679 putative cytosolic protein\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"M28_Spy0270 gidB; glucose inhibited division protein B\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"M28_Spy1410 mraW; S-adenosyl-methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"M28_Spy0323 corrin\/porphyrin methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"M28_Spy1169 hemolysin\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"M28_Spy1640 23S rRNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"M28_Spy1897 putative cytosolic protein\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"M28_Spy0602 methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"M28_Spy1200 radical SAM family enzyme\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"M28_Spy1090 tRNA (uracil-5-)-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"M28_Spy0299 ribosomal large subunit pseudouridine synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"M28_Spy0618 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"M28_Spy0825 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"M28_Spy1742 ribosomal large subunit pseudouridine synthase D\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"M28_Spy1584 ribosomal-protein-alanine acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
				},
				{
					"name":"M28_Spy0636 rimM; 16S rRNA processing protein\tK02860 rimM; 16S rRNA processing protein RimM"
				},
				{
					"name":"M28_Spy1680 ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"M28_Spy1780 hypothetical protein\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy1642 hypothetical protein\tK11145 mrnC; mini-ribonuclease III [EC:3.1.26.-]"
				},
				{
					"name":"M28_Spy0215 ribonuclease M5\tK05985 rnmV; ribonuclease M5 [EC:3.1.26.8]"
				},
				{
					"name":"M28_Spy1148 deaD; ATP-dependent RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"M28_Spy1406 ATP-dependent RNA helicase\tK18692 cshB; ATP-dependent RNA helicase CshB [EC:5.6.2.7]"
				},
				{
					"name":"M28_Spy0217 GTPase\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"M28_Spy0279 pgdA; GTP-binding protein\tK03977 engA; GTPase"
				},
				{
					"name":"M28_Spy0856 GTP-binding protein\tK14540 rbgA; ribosome biogenesis GTPase A"
				},
				{
					"name":"M28_Spy0703 hflX; GTP-binding protein\tK03665 hflX; GTPase"
				},
				{
					"name":"M28_Spy0253 GTP-binding protein\tK06948 yqeH; 30S ribosome assembly GTPase"
				},
				{
					"name":"M28_Spy0839 SUA5 protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"M28_Spy1674 relA; GTP pyrophosphokinase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"M28_Spy1451 rbfA; ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
				},
				{
					"name":"M28_Spy1456 putative cytosolic protein\tK09748 rimP; ribosome maturation factor RimP"
				},
				{
					"name":"M28_Spy1887 putative cytosolic protein\tK14761 rlbA; ribosome-associated protein"
				},
				{
					"name":"M28_Spy0257 iojap protein family\tK09710 ybeB; ribosome-associated protein"
				},
				{
					"name":"M28_Spy0374 putative metal-binding protein\tK07042 ybeY; probable rRNA maturation factor"
				},
				{
					"name":"M28_Spy0254 putative RNA binding protein\tK07574 yhbY; RNA-binding protein"
				},
				{
					"name":"M28_Spy1366 ribosome-associated factor Y\tK05808 hpf; ribosome hibernation promoting factor"
				},
				{
					"name":"M28_Spy0004 GTP-binding protein\tK06942 ychF; ribosome-binding ATPase"
				},
				{
					"name":"M28_Spy0273 putative cytosolic protein\tK07040 yceD; DUF177 domain-containing protein"
				}
				]
			},
			{
				"name":"03016 Transfer RNA biogenesis [BR:spb03016]",
				"children":[
				{
					"name":"M28_Spy0705 elaC; metal-dependent hydrolase\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"M28_Spy0653 papS; poly(A) polymerase\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				},
				{
					"name":"M28_Spy1661 proS; prolyl-tRNA synthetase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"M28_Spy1182 ileS; isoleucyl-tRNA synthetase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"M28_Spy0145 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"M28_Spy0332 metS; methionyl-tRNA synthetase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"M28_Spy1817 argS; arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"M28_Spy0474 lysS; lysyl-tRNA synthetase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"M28_Spy1822 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"M28_Spy1126 alaS; alanyl-tRNA synthetase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"M28_Spy0516 asnS; asnS\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"M28_Spy0415 thrS; threonyl-tRNA synthetase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"M28_Spy1472 serS; seryl-tRNA synthetase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"M28_Spy1643 cysS; cysteinyl-tRNA synthetase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"M28_Spy1296 valS; valyl-tRNA synthetase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"M28_Spy1823 hisS; histidyl-tRNA synthetase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"M28_Spy0566 pheS; phenylalanyl-tRNA synthetase alpha chain\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy0567 pheT; phenylalanyl-tRNA synthetase beta chain\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"M28_Spy0079 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"M28_Spy1891 trsA; tryptophanyl-tRNA synthetase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"M28_Spy1673 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"M28_Spy1461 hit; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"M28_Spy1457 tRNA (m(7)G46) methyltransferase\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"M28_Spy1606 tRNA pseudouridine synthase A\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"M28_Spy0934 truB; tRNA pseudouridine synthase B\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"M28_Spy0610 nifS1; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0820 nifS2; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0839 SUA5 protein\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"M28_Spy0702 miaA; tRNA delta(2)-isopentenylpyrophosphate transferase\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"M28_Spy0768 thdF; tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"M28_Spy1870 gidA; glucose inhibited division protein A\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"M28_Spy0201 fasX; ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"M28_Spy1428 glyQ; glycyl-tRNA synthetase alpha chain\tK01878 glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy1427 glyS; glycyl-tRNA synthetase beta chain\tK01879 glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"M28_Spy0197 gltX; glutamyl-tRNA synthetase\tK09698 gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				},
				{
					"name":"M28_Spy0477 transcriptional regulator\tK03976 ybaK; Cys-tRNA(Pro)\/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]"
				},
				{
					"name":"M28_Spy0177 tRNA-specific adenosine deaminase\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				},
				{
					"name":"M28_Spy0102 tRNA-dihydrouridine synthase\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				},
				{
					"name":"M28_Spy0866 gid; glucose inhibited division protein A\tK04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]"
				},
				{
					"name":"M28_Spy0637 trmD; tRNA (guanine-N(1)-)-methyltransferase\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"M28_Spy0711 para-aminobenzoate synthase component I\tK06967 trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]"
				},
				{
					"name":"M28_Spy0301 23S rRNA methyltransferase\tK03216 trmL; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				},
				{
					"name":"M28_Spy0288 23S rRNA methyltransferase\tK03437 spoU; RNA methyltransferase, TrmH family"
				},
				{
					"name":"M28_Spy1872 trmU; tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"M28_Spy1134 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"M28_Spy0508 iron-sulfur cluster-binding protein\tK18979 queG; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"M28_Spy0192 putative cytosolic protein\tK09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"M28_Spy0173 tgt; queuine tRNA-ribosyltransferase\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"M28_Spy0611 thiI; thiamine biosynthesis protein\tK03151 thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"M28_Spy0011 tilS; tRNA(Ile)-lysidine synthetase\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"M28_Spy1585 glycoprotease protein family\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"M28_Spy1583 O-sialoglycoprotein endopeptidase\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"M28_Spy1465 ATP\/GTP hydrolase\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"M28_Spy0259 putative cytosolic protein\tK27343 tmcAL; tRNAmet cytidine acetate ligase [EC:6.3.1.22]"
				},
				{
					"name":"M28_Spy0402 exoribonuclease II\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"M28_Spy1648 polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				}
				]
			},
			{
				"name":"03012 Translation factors [BR:spb03012]",
				"children":[
				{
					"name":"M28_Spy1452 infB; bacterial protein translation initiation factor 2 (IF-2)\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"M28_Spy0598 infC; bacterial protein translation initiation factor 3 (IF-3)\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"M28_Spy0729 ABC transporter ATP-binding protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"M28_Spy1765 protein translation elongation factor Ts (EF-Ts)\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"M28_Spy0487 protein translation elongation factor Tu (EF-TU)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"M28_Spy0226 fus; protein translation elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"M28_Spy0837 prfA; bacterial peptide chain release factor 1\tK02835 prfA; peptide chain release factor 1"
				},
				{
					"name":"M28_Spy0366 rrf; ribosome recycling factor\tK02838 frr; ribosome recycling factor"
				},
				{
					"name":"M28_Spy0838 hemK; peptide release factor-glutamine N5-methyltransferase\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]"
				},
				{
					"name":"M28_Spy0005 pth; peptidyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
				},
				{
					"name":"M28_Spy0065 infA; bacterial protein translation initiation factor 1 (IF-1)\tK02518 infA; translation initiation factor IF-1"
				},
				{
					"name":"M28_Spy1534 efp; protein translation elongation factor P\tK02356 efp; elongation factor P"
				},
				{
					"name":"M28_Spy0509 prfB; bacterial peptide chain release factor 2\tK02836 prfB; peptide chain release factor 2"
				},
				{
					"name":"M28_Spy1149 prfC; bacterial peptide chain release factor 3\tK02837 prfC; peptide chain release factor 3"
				}
				]
			},
			{
				"name":"03110 Chaperones and folding catalysts [BR:spb03110]",
				"children":[
				{
					"name":"M28_Spy1749 clpC; negative regulator of genetic competence\tK03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC"
				},
				{
					"name":"M28_Spy1179 clpE; ATP-dependent Clp protease ATP-binding subunit\tK03697 clpE; ATP-dependent Clp protease ATP-binding subunit ClpE"
				},
				{
					"name":"M28_Spy0674 clpL; ATP-dependent protease ATP-binding subunit\tK04086 clpL; ATP-dependent Clp protease ATP-binding subunit ClpL"
				},
				{
					"name":"M28_Spy0671 clpX; ATP-dependent Clp protease ATP-binding subunit\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"M28_Spy1486 dnaJ; chaperone protein\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"M28_Spy0103 putative HSP33\tK04083 hslO; molecular chaperone Hsp33"
				},
				{
					"name":"M28_Spy1488 grpE; grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"M28_Spy1748 groES; 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"M28_Spy1898 htrA; protease Do\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"M28_Spy0013 ftsH; cell division protein\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
				},
				{
					"name":"M28_Spy0554 atpB; ATP synthase A chain\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"M28_Spy1700 scpA; C5A peptidase precursor\tK08652 C5AP; C5a peptidase [EC:3.4.21.110]"
				},
				{
					"name":"M28_Spy0360 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1372 peptidyl-prolyl cis-trans isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1127 surA; peptidyl-prolyl cis-trans isomerase\tK07533 prsA; foldase protein PrsA [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1718 protein export protein prsA precursor\tK07533 prsA; foldase protein PrsA [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1547 trx.2; thioredoxin\tK03671 TXN; thioredoxin"
				}
				]
			},
			{
				"name":"04131 Membrane trafficking [BR:spb04131]",
				"children":[
				{
					"name":"M28_Spy1358 alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"M28_Spy1158 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"M28_Spy0960 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				}
				]
			},
			{
				"name":"04121 Ubiquitin system"
			},
			{
				"name":"03051 Proteasome"
			},
			{
				"name":"03032 DNA replication proteins [BR:spb03032]",
				"children":[
				{
					"name":"M28_Spy0774 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"M28_Spy1162 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"M28_Spy0001 dnaA; chromosomal replication initiator protein\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"M28_Spy1867 holB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"M28_Spy0578 dnaG; DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"M28_Spy0277 dnaB; replicative DNA helicase\tK03346 dnaB; replication initiation and membrane attachment protein"
				},
				{
					"name":"M28_Spy0278 dnaI; primosomal protein\tK11144 dnaI; primosomal protein DnaI"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy0962 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1660 polC; DNA polymerase III alpha subunit\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0002 dnaN; DNA polymerase III, beta chain\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1140 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0320 dnaX; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1105 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0857 ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"M28_Spy1552 ribonuclease HIII\tK03471 rnhC; ribonuclease HIII [EC:3.1.26.4]"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"M28_Spy0848 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0532 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0692 parC; topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0691 parE; topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0859 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				}
				]
			},
			{
				"name":"03036 Chromosome and associated proteins [BR:spb03036]",
				"children":[
				{
					"name":"M28_Spy0774 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"M28_Spy0426 acpA; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"M28_Spy1162 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"M28_Spy0001 dnaA; chromosomal replication initiator protein\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"M28_Spy1198 dpr; non-specific DNA-binding protein Dps\tK04047 dps; starvation-inducible DNA-binding protein"
				},
				{
					"name":"M28_Spy0427 smc; chromosome partition protein smc\tK03529 smc; chromosome segregation protein"
				},
				{
					"name":"M28_Spy0297 putative cytosolic protein\tK05896 scpA; segregation and condensation protein A"
				},
				{
					"name":"M28_Spy0298 putative cytosolic protein\tK06024 scpB; segregation and condensation protein B"
				},
				{
					"name":"M28_Spy1189 ftsA; cell division protein\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"M28_Spy0008 divIC; cell division protein\tK13052 divIC; cell division protein DivIC"
				},
				{
					"name":"M28_Spy0510 ftsE; cell division ATP-binding protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0361 ftsK; cell division protein\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family"
				},
				{
					"name":"M28_Spy1409 ftsL; cell division protein\tK03586 ftsL; cell division protein FtsL"
				},
				{
					"name":"M28_Spy1190 divIB; cell division protein\tK03589 ftsQ; cell division protein FtsQ"
				},
				{
					"name":"M28_Spy0485 ftsW; cell division protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"M28_Spy0511 ftsX; cell division protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"M28_Spy1188 ftsZ; cell division protein\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"M28_Spy0533 septation ring formation regulator\tK06286 ezrA; septation ring formation regulator"
				},
				{
					"name":"M28_Spy1183 divIVAS; cell division initiation protein DivIVA\tK04074 divIVA; cell division initiation protein"
				},
				{
					"name":"M28_Spy1186 putative cytosolic protein\tK09772 sepF; cell division inhibitor SepF"
				},
				{
					"name":"M28_Spy1255 ParB-like protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"M28_Spy1899 parB; chromosome partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"M28_Spy0692 parC; topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0691 parE; topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy1870 gidA; glucose inhibited division protein A\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"M28_Spy0270 gidB; glucose inhibited division protein B\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"M28_Spy0866 gid; glucose inhibited division protein A\tK04094 trmFO; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]"
				},
				{
					"name":"M28_Spy0672 GTP-binding protein\tK03978 engB; GTP-binding protein"
				},
				{
					"name":"M28_Spy0519 putative cytosolic protein\tK09762 whiA; cell division protein WhiA"
				}
				]
			},
			{
				"name":"03400 DNA repair and recombination proteins [BR:spb03400]",
				"children":[
				{
					"name":"M28_Spy1175 phr; deoxyribodipyrimidine photolyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"M28_Spy0688 ung; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"M28_Spy1544 mutY; A\/G-specific adenine DNA glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"M28_Spy0710 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"M28_Spy0717 mutator protein T\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"M28_Spy1180 mutT; mutator protein (7,8-dihydro-8-oxoguanine-triphosphatase)\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"M28_Spy0193 deoxyuridine 5'-triphosphate nucleotidohydrolase\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"M28_Spy1785 tag; DNA-3-methyladenine glycosylase\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"M28_Spy0396 fpg; formamidopyrimidine-DNA glycosylase\tK10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]"
				},
				{
					"name":"M28_Spy0327 exoA; exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"M28_Spy0707 recJ; single-stranded-DNA-specific exonuclease\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0551 lig; NAD-dependent DNA ligase\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"M28_Spy0157 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1537 uvrA; excinuclease ABC subunit A\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"M28_Spy1056 uvrB; excinuclease ABC subunit B\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"M28_Spy0765 uvrC; excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"M28_Spy0949 pcrA; DNA helicase II\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy0081 rpoB; DNA-directed RNA polymerase beta chain\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0082 rpoC; DNA-directed RNA polymerase beta' chain\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0069 rpoA; DNA-directed RNA polymerase alpha chain\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy1600 rpoE; DNA-directed RNA polymerase delta chain\tK03048 rpoE; DNA-directed RNA polymerase subunit delta"
				},
				{
					"name":"M28_Spy1381 DNA-directed RNA polymerase omega chain\tK03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]"
				},
				{
					"name":"M28_Spy0006 trcF; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1814 mutS; DNA mismatch repair protein\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"M28_Spy1549 mutS2; DNA mismatch repair protein\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"M28_Spy1788 mutL; DNA mismatch repair protein\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"M28_Spy1172 exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"M28_Spy1171 xseB; exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"M28_Spy0962 dnaE; DNA polymerase III alpha subunit\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1660 polC; DNA polymerase III alpha subunit\tK03763 polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0002 dnaN; DNA polymerase III, beta chain\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1140 DNA polymerase III, delta subunit\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0320 dnaX; DNA polymerase III, delta' subunit\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1570 dnaQ; DNA polymerase III, epsilon chain\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1105 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1554 recD; exodeoxyribonuclease V alpha chain\tK03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]"
				},
				{
					"name":"M28_Spy1783 recA; DNA recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"M28_Spy1786 ruvA; holliday junction DNA helicase\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"M28_Spy0035 ruvB; holliday junction DNA helicase\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy1380 priA; primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy0194 radA; DNA repair protein\tK04485 radA; DNA repair protein RadA\/Sms"
				},
				{
					"name":"M28_Spy1888 recF; DNA replication and repair protein recF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"M28_Spy1509 recG; ATP-dependent DNA helicase\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"M28_Spy0019 recO; DNA repair protein\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"M28_Spy1153 recR; recombination protein\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"M28_Spy1167 recN; DNA repair protein\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"M28_Spy1395 recU; recombination protein\tK03700 recU; recombination protein U"
				},
				{
					"name":"M28_Spy0574 rexA; ATP-dependent nuclease subunit A\tK16898 addA; ATP-dependent helicase\/nuclease subunit A [EC:5.6.2.4 3.1.-.-]"
				},
				{
					"name":"M28_Spy0573 rexB; ATP-dependent nuclease subunit B\tK16899 addB; ATP-dependent helicase\/nuclease subunit B [EC:5.6.2.4 3.1.-.-]"
				},
				{
					"name":"M28_Spy0749 cas1; Type II CRISPR associated endonuclease, Cas1\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"M28_Spy1290 cas1; Type I-C CRISPR associated endonuclease, Cas1\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"M28_Spy0398 ATPase\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
				},
				{
					"name":"M28_Spy0848 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0532 gyrB; DNA gyrase subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0859 DNA topoisomerase I\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"M28_Spy1162 DNA-binding protein HU\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"M28_Spy1556 dinP; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"M28_Spy1361 recX; regulatory protein\tK03565 recX; regulatory protein"
				},
				{
					"name":"M28_Spy0514 dinG; ATP-dependent helicase\tK03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]"
				},
				{
					"name":"M28_Spy0336 nrdE.1; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1116 nrdE.2; ribonucleoside-diphosphate reductase alpha chain\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy0334 nrdF.1; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy1118 nrdF.2; ribonucleoside-diphosphate reductase beta chain\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"M28_Spy0525 phosphoesterase, DHH family protein\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			},
			{
				"name":"03029 Mitochondrial biogenesis [BR:spb03029]",
				"children":[
				{
					"name":"M28_Spy1452 infB; bacterial protein translation initiation factor 2 (IF-2)\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"M28_Spy0598 infC; bacterial protein translation initiation factor 3 (IF-3)\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"M28_Spy1765 protein translation elongation factor Ts (EF-Ts)\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"M28_Spy0487 protein translation elongation factor Tu (EF-TU)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"M28_Spy0226 fus; protein translation elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"M28_Spy0376 era; putative GTP-binding protein\tK03595 era; GTPase"
				},
				{
					"name":"M28_Spy0079 tyrS; tyrosyl-tRNA synthetase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"M28_Spy0145 leuS; leucyl-tRNA synthetase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"M28_Spy1822 aspS; aspartyl-tRNA synthetase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"M28_Spy1817 argS; arginyl-tRNA synthetase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"M28_Spy1496 gatA; aspartyl\/glutamyl-tRNA amidotransferase subunit A\tK02433 gatA; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy1495 gatB; aspartyl\/glutamyl-tRNA amidotransferase subunit B\tK02434 gatB; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy1497 gatC; glutamyl-tRNA(Gln) amidotransferase subunit C\tK02435 gatC; aspartyl-tRNA(Asn)\/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]"
				},
				{
					"name":"M28_Spy0100 ssb; single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1268 ssb2.1; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1541 ssb2.2; phage single-strand DNA binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy1488 grpE; grpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"M28_Spy1748 groES; 10 kDa chaperonin\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"M28_Spy1486 dnaJ; chaperone protein\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"M28_Spy0610 nifS1; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0820 nifS2; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0202 hypothetical protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy0286 inner membrane protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				}
				]
			}
			]
		},
		{
			"name":"09183 Protein families: signaling and cellular processes",
			"children":[
			{
				"name":"02000 Transporters [BR:spb02000]",
				"children":[
				{
					"name":"M28_Spy0782 srtT; ABC transporter (ATP binding)-lantibiotic associated\tK20485 nisT; ATP-binding cassette, subfamily B, bacterial NisT\/SpaT"
				},
				{
					"name":"M28_Spy0190 ABC transporter ATP-binding and permease protein\tK18891 patA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0191 ABC transporter ATP-binding and permease protein\tK18892 patB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0844 multidrug resistance ABC transporter ATP-binding and permease protein\tK18887 efrA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy0845 multidrug resistance ABC transporter ATP-binding and permease protein\tK18888 efrB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"M28_Spy1514 ABC transporter ATP-binding protein\tK06148 ABCC-BAC; ATP-binding cassette, subfamily C, bacterial"
				},
				{
					"name":"M28_Spy0654 ABC transporter ATP-binding protein uup\tK15738 uup; ABC transport system ATP-binding\/permease protein"
				},
				{
					"name":"M28_Spy0763 iron(III)-binding protein\tK02012 afuA; iron(III) transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0806 spermidine\/putrescine-binding protein\tK11069 potD; spermidine\/putrescine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0805 potC; spermidine\/putrescine transport system permease protein\tK11070 potC; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"M28_Spy0804 potB; spermidine\/putrescine transport system permease protein\tK11071 potB; spermidine\/putrescine transport system permease protein"
				},
				{
					"name":"M28_Spy0803 potA; spermidine\/putrescine transport ATP-binding protein\tK11072 potA; spermidine\/putrescine transport system ATP-binding protein [EC:7.6.2.11]"
				},
				{
					"name":"M28_Spy0156 opuABC; glycine betaine-binding protein\tK02001 proW; glycine betaine\/proline transport system permease protein"
				},
				{
					"name":"M28_Spy0155 opuAA; glycine betaine transport ATP-binding protein\tK02000 proV; glycine betaine\/proline transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"M28_Spy0830 glycine betaine transport system permease protein\tK05845 opuC; osmoprotectant transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0829 proV; glycine betaine transport ATP-binding protein\tK05847 opuA; osmoprotectant transport system ATP-binding protein [EC:7.6.2.9]"
				},
				{
					"name":"M28_Spy1670 msmK; multiple sugar transport ATP-binding protein\tK10112 msmX; multiple sugar transport system ATP-binding protein [EC:7.5.2.-]"
				},
				{
					"name":"M28_Spy1039 malE; maltose\/maltodextrin-binding protein\tK15770 cycB; arabinogalactan oligomer \/ maltooligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1048 malX; maltose\/maltodextrin-binding protein\tK15770 cycB; arabinogalactan oligomer \/ maltooligosaccharide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1040 malF; maltose transport system permease protein\tK15771 ganP; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1045 malC; maltose transport system permease protein\tK15771 ganP; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1041 malG; maltose transport system permease protein\tK15772 ganQ; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1044 malD; maltodextrin transport system permease protein\tK15772 ganQ; arabinogalactan oligomer \/ maltooligosaccharide transport system permease protein"
				},
				{
					"name":"M28_Spy1349 sugar-binding protein\tK17318 lplA; putative aldouronate transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1351 sugar transport system permease protein\tK17319 lplB; putative aldouronate transport system permease protein"
				},
				{
					"name":"M28_Spy1350 sugar transport system permease protein\tK17320 lplC; putative aldouronate transport system permease protein"
				},
				{
					"name":"M28_Spy0135 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"M28_Spy0914 nucleoside-binding protein\tK07335 bmpA; basic membrane protein A and related proteins"
				},
				{
					"name":"M28_Spy0912 nucleoside transport system permease protein\tK23535 nupB; general nucleoside transport system permease protein"
				},
				{
					"name":"M28_Spy0911 nucleoside transport system permease protein\tK23536 nupC; general nucleoside transport system permease protein"
				},
				{
					"name":"M28_Spy0913 nucleoside transport ATP-binding protein\tK23537 nupA; general nucleoside transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0207 N-acetylneuraminate-binding protein\tK02027 ABC.MS.S; multiple sugar transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0208 N-acetylneuraminate transport system permease protein\tK02025 ABC.MS.P; multiple sugar transport system permease protein"
				},
				{
					"name":"M28_Spy0209 N-acetylneuraminate transport system permease protein\tK02026 ABC.MS.P1; multiple sugar transport system permease protein"
				},
				{
					"name":"M28_Spy0928 pstS; phosphate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0927 pstC; phosphate transport system permease protein\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"M28_Spy0926 pstA; phosphate transport system permease protein\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"M28_Spy0924 pstB; phosphate transport ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"M28_Spy0925 pstB2; phosphate transport ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"M28_Spy1057 glnH; transporter\tK10036 glnH; glutamine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1058 glnQ.2; glutamine transport ATP-binding protein\tK10038 glnQ; glutamine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0262 ABC transporter substrate-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0686 cystine-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0687 cystine transport system permease protein\tK10009 tcyB; L-cystine transport system permease protein"
				},
				{
					"name":"M28_Spy1404 amino acid ABC transporter permease protein\tK10009 tcyB; L-cystine transport system permease protein"
				},
				{
					"name":"M28_Spy1403 transporter\tK10010 tcyC; L-cystine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0575 arginine-binding protein\tK23059 artP; arginine\/lysine\/histidine transporter system substrate-binding protein"
				},
				{
					"name":"M28_Spy1177 artQ; arginine transport system permease protein\tK17077 artQ; arginine\/lysine\/histidine transport system permease protein"
				},
				{
					"name":"M28_Spy1176 artP; arginine transport ATP-binding protein\tK23060 artR; arginine\/lysine\/histidine transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0263 ABC transporter substrate-binding protein\tK02073 metQ; D-methionine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0265 ABC transporter permease protein\tK02072 metI; D-methionine transport system permease protein"
				},
				{
					"name":"M28_Spy0264 ABC transporter ATP-binding protein\tK02071 metN; D-methionine transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0722 ABC transporter substrate-binding protein\tK01989 K01989; putative tryptophan\/tyrosine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0724 ABC transporter permease protein\tK05832 K05832; putative tryptophan\/tyrosine transport system permease protein"
				},
				{
					"name":"M28_Spy0725 ABC transporter ATP-binding protein\tK05833 K05833; putative tryptophan\/tyrosine transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0230 ABC transporter amino acid-binding protein\tK17073 lysX1; putative lysine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0229 amino acid transport ATP-binding protein\tK17076 lysY; putative lysine transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0954 histidine-binding protein\tK02030 ABC.PA.S; polar amino acid transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0956 histidine transport system permease protein M\tK02029 ABC.PA.P; polar amino acid transport system permease protein"
				},
				{
					"name":"M28_Spy0955 histidine transport ATP-binding protein P\tK02028 ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:7.4.2.1]"
				},
				{
					"name":"M28_Spy0244 oppA; oligopeptide-binding protein\tK15580 oppA; oligopeptide transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0245 oppB; oligopeptide transport system permease protein\tK15581 oppB; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0246 oppC; oligopeptide transport system permease protein\tK15582 oppC; oligopeptide transport system permease protein"
				},
				{
					"name":"M28_Spy0247 oppD; oligopeptide transport ATP-binding protein\tK15583 oppD; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0248 oppF; oligopeptide transport ATP-binding protein\tK10823 oppF; oligopeptide transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1689 dppA; dipeptide-binding protein\tK02035 ABC.PE.S; peptide\/nickel transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1690 dppB; dipeptide transport system permease protein\tK02033 ABC.PE.P; peptide\/nickel transport system permease protein"
				},
				{
					"name":"M28_Spy1691 dppC; dipeptide transport system permease protein\tK02034 ABC.PE.P1; peptide\/nickel transport system permease protein"
				},
				{
					"name":"M28_Spy1692 dppD; dipeptide transport ATP-binding protein\tK02031 ddpD; peptide\/nickel transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1693 dppE; dipeptide transport ATP-binding protein\tK02032 ddpF; peptide\/nickel transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0312 fhuD; ferrichrome-binding protein\tK25308 fhuD; ferric hydroxamate\/heme transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0311 fhuB; ferrichrome transport system permease protein\tK25288 fhuB; ferric hydroxamate\/heme transport system permease protein"
				},
				{
					"name":"M28_Spy0310 fhuG; ferrichrome transport system permease protein\tK25289 fhuG; ferric hydroxamate\/heme transport system permease protein"
				},
				{
					"name":"M28_Spy0313 fhuA; ferrichrome transport ATP-binding protein\tK25290 fhuA; ferric hydroxamate\/heme transport system ATP-binding protein [EC:7.2.2.16]"
				},
				{
					"name":"M28_Spy1518 ferrichrome-binding protein\tK25113 htsA; heme transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1517 ferrichrome transport system permease protein fhuB\tK25114 htsB; heme transport system permease protein"
				},
				{
					"name":"M28_Spy1516 fhuC; ferrichrome transport ATP-binding protein\tK25115 htsC; heme transport system ATP-binding protein [EC:7.6.2.5]"
				},
				{
					"name":"M28_Spy1519 shp; putative heme binding protein\tK25119 shp; heme transport system cell surface heme-binding protein"
				},
				{
					"name":"M28_Spy1520 putative Fe3+-siderophore transport protein\tK25120 shr; heme sequestration protein"
				},
				{
					"name":"M28_Spy0521 high-affinity zinc uptake system protein ZnuA precursor\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy1696 lmb; laminin binding protein\tK09815 znuA; zinc transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0077 adcB; high-affinity zinc uptake system membrane protein\tK09816 znuB; zinc transport system permease protein"
				},
				{
					"name":"M28_Spy0076 adcC; high-affinity zinc uptake system ATP-binding protein\tK09817 znuC; zinc transport system ATP-binding protein [EC:7.2.2.20]"
				},
				{
					"name":"M28_Spy0357 mtsA; manganese-binding protein\tK11704 mtsA; iron\/zinc\/manganese\/copper transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0359 mtsC; manganese transport system membrane protein\tK11705 mtsC; iron\/zinc\/manganese\/copper transport system permease protein"
				},
				{
					"name":"M28_Spy0358 mtsB; manganese transport system ATP-binding protein\tK11706 mtsB; iron\/zinc\/manganese\/copper transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0175 BioY\tK03523 bioY; biotin transport system substrate-specific component"
				},
				{
					"name":"M28_Spy1513 permease\tK16926 htsT; energy-coupling factor transport system substrate-specific component"
				},
				{
					"name":"M28_Spy0480 integral membrane protein\tK16927 cbrT; energy-coupling factor transport system substrate-specific component"
				},
				{
					"name":"M28_Spy1512 cobalt transport protein cbiQ\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"M28_Spy1876 cbiQ; cobalt transport protein\tK16785 ecfT; energy-coupling factor transport system permease protein"
				},
				{
					"name":"M28_Spy1878 cbiO1; cobalt transport ATP-binding protein\tK16786 ecfA1; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"M28_Spy1877 cbiO2; cobalt transport ATP-binding protein\tK16787 ecfA2; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"M28_Spy1511 cobalt transport ATP-binding protein cbiO\tK01552 ecfA; energy-coupling factor transport system ATP-binding protein [EC:7.-.-.-]"
				},
				{
					"name":"M28_Spy0786 srtE; lantibiotic transport permease protein\tK20491 nisE; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0787 srtG; lantibiotic transport permease protein\tK20492 nisG; lantibiotic transport system permease protein"
				},
				{
					"name":"M28_Spy0785 srtF; lantibiotic transport ATP-binding protein\tK20490 nisF; lantibiotic transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0548 sagI; streptolysin S export transmembrane protein\tK25142 lnrN; linearmycin\/streptolysin S transport system permease protein"
				},
				{
					"name":"M28_Spy0547 sagH; streptolysin S export transmembrane protein\tK25143 lnrM; linearmycin\/streptolysin S transport system permease protein"
				},
				{
					"name":"M28_Spy0546 sagG; streptolysin S export ATP-binding protein\tK25144 lnrL; linearmycin\/streptolysin S transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0627 ABC transporter permease protein\tK24948 yknZ; antimicrobial peptide resistance transport system permease protein"
				},
				{
					"name":"M28_Spy1710 ABC transporter permease protein\tK24948 yknZ; antimicrobial peptide resistance transport system permease protein"
				},
				{
					"name":"M28_Spy0626 ABC transporter ATP-binding protein\tK24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"M28_Spy1711 ABC transporter ATP-binding protein\tK24949 yknY; antimicrobial peptide resistance transport system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"M28_Spy0511 ftsX; cell division protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"M28_Spy0510 ftsE; cell division ATP-binding protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0418 ABC transporter permease protein\tK25154 evrC; viologen exporter family transport system permease protein"
				},
				{
					"name":"M28_Spy0417 putative transmembrane protein\tK25155 evrB; viologen exporter family transport system permease protein"
				},
				{
					"name":"M28_Spy0416 putative ABC transporter\tK25156 evrA; viologen exporter family transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1459 ecsB; ABC-type exoprotein transporter permease component EcsB\tK25157 ecsB; ABC-2 type transport system permease protein"
				},
				{
					"name":"M28_Spy1460 ecsA; ABC-type exoprotein transporter ATP-binding protein EcsA\tK25158 ecsA; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0584 rgpCc; polysaccharide export ABC transporter permease protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"M28_Spy1415 proB; ABC transporter permease protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"M28_Spy1506 hypothetical protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"M28_Spy0585 rgpDc; polysaccharide export ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0964 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1416 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1507 putative ATP transporter\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0570 ABC transporter permease protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"M28_Spy0938 ABC transporter permease protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"M28_Spy1617 salY; ABC transporter permease protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"M28_Spy0571 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0939 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1574 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy1618 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"M28_Spy0237 ABC transporter ATP-binding protein\tK09013 sufC; Fe-S cluster assembly ATP-binding protein"
				},
				{
					"name":"M28_Spy0041 Na+ driven multidrug efflux pump\tK26937 dinF; MATE family, multidrug efflux pump"
				},
				{
					"name":"M28_Spy1129 oxalate\/formate antiporter\tK08177 oxlT; MFS transporter, OFA family, oxalate\/formate antiporter"
				},
				{
					"name":"M28_Spy0350 phosphoglycerate transporter protein\tK02445 glpT; MFS transporter, OPA family, glycerol-3-phosphate transporter"
				},
				{
					"name":"M28_Spy0399 multidrug resistance protein B\tK08161 mdtG; MFS transporter, DHA1 family, multidrug resistance protein"
				},
				{
					"name":"M28_Spy1787 lmrP; multidrug resistance protein B\tK08152 lmrP; MFS transporter, DHA1 family, multidrug resistance protein B"
				},
				{
					"name":"M28_Spy0454 multidrug resistance protein B\tK18926 lmrB; MFS transporter, DHA2 family, lincomycin resistance protein"
				},
				{
					"name":"M28_Spy1113 pstI; phosphoenolpyruvate-protein phosphotransferase\tK08483 ptsI; phosphoenolpyruvate-protein phosphotransferase (PTS system enzyme I) [EC:2.7.3.9]"
				},
				{
					"name":"M28_Spy1114 ptsH; phosphocarrier protein HPr\tK02784 ptsH; phosphocarrier protein HPr"
				},
				{
					"name":"M28_Spy1678 PTS system, glucose-specific IIABC component\tK20108 malT; maltose PTS system EIICB or EIICBA component [EC:2.7.1.208]"
				},
				{
					"name":"M28_Spy1529 scrA; PTS system, sucrose-specific IIABC component\tK02810 scrA; sucrose PTS system EIIBCA or EIIBC component [EC:2.7.1.211]"
				},
				{
					"name":"M28_Spy0456 PTS system, beta-glucoside-specific IIABC component\tK02757 bglF; beta-glucoside PTS system EIICBA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy1768 PTS system, trehalose-specific IIBC component\tK02819 treB; trehalose PTS system EIIBC or EIIBCA component [EC:2.7.1.201]"
				},
				{
					"name":"M28_Spy0643 fruA; PTS system, fructose-specific IIABC component\tK02770 fruA; fructose PTS system EIIBC or EIIC component [EC:2.7.1.202]"
				},
				{
					"name":"M28_Spy1624 lacF; PTS system, lactose-specific IIA component\tK02786 lacF; lactose PTS system EIIA component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1623 lacE; PTS system, lactose-specific IIBC component\tK02788 lacE; lactose PTS system EIICB component [EC:2.7.1.207]"
				},
				{
					"name":"M28_Spy1062 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1733 PTS system, cellobiose-specific IIA component\tK02759 celC; cellobiose PTS system EIIA component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1063 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1732 PTS system, cellobiose-specific IIB component\tK02760 celA; cellobiose PTS system EIIB component [EC:2.7.1.196 2.7.1.205]"
				},
				{
					"name":"M28_Spy1060 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy1731 PTS system, cellobiose-specific IIC component\tK02761 celB; cellobiose PTS system EIIC component"
				},
				{
					"name":"M28_Spy1444 PTS system, galactose-specific IIA component\tK20112 gatA; galactose PTS system EIIA component [EC:2.7.1.204]"
				},
				{
					"name":"M28_Spy1443 PTS system, galactose-specific IIB component\tK20113 gatB; galactose PTS system EIIB component [EC:2.7.1.204]"
				},
				{
					"name":"M28_Spy1442 PTS system, galactose-specific IIC component\tK20114 gatC; galactose PTS system EIIC component"
				},
				{
					"name":"M28_Spy1468 manL; PTS system, mannose-specific IIAB component\tK02794 manX; mannose PTS system EIIAB component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy0757 PTS system, mannose\/fructose family IIA component\tK02793 manXa; mannose PTS system EIIA component [EC:2.7.1.191]"
				},
				{
					"name":"M28_Spy1469 manM; PTS system, mannose-specific IIC component\tK02795 manY; mannose PTS system EIIC component"
				},
				{
					"name":"M28_Spy0760 ptsD; PTS system, mannose\/fructose family IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy1470 manN; PTS system, mannose-specific IID component\tK02796 manZ; mannose PTS system EIID component"
				},
				{
					"name":"M28_Spy0758 ptsB; PTS system, mannose\/fructose family IIB component\tK19507 gfrB; fructoselysine\/glucoselysine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0759 ptsC; PTS system, mannose\/fructose family IIC component\tK19508 gfrC; fructoselysine\/glucoselysine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0502 PTS system, N-acetylgalactosamine-specific IIA component\tK02744 agaF; N-acetylgalactosamine PTS system EIIA component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0500 agaV; PTS system, N-acetylgalactosamine-specific IIB component\tK02745 agaV; N-acetylgalactosamine PTS system EIIB component [EC:2.7.1.-]"
				},
				{
					"name":"M28_Spy0499 PTS system, N-acetylgalactosamine-specific IIC component\tK02746 agaW; N-acetylgalactosamine PTS system EIIC component"
				},
				{
					"name":"M28_Spy0498 agaD; PTS system, N-acetylgalactosamine-specific IID component\tK02747 agaE; N-acetylgalactosamine PTS system EIID component"
				},
				{
					"name":"M28_Spy0148 PTS system, 3-keto-L-gulonate specific IIA component\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1652 transcription antiterminator, BglG family\tK02821 ulaC; ascorbate PTS system EIIA or EIIAB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0147 PTS system, 3-keto-L-gulonate specific IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy1651 PTS system, IIB component\tK02822 ulaB; ascorbate PTS system EIIB component [EC:2.7.1.194]"
				},
				{
					"name":"M28_Spy0146 PTS system, 3-keto-L-gulonate specific IIC component\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy1650 putative transport protein sgaT\tK03475 ulaA; ascorbate PTS system EIIC component"
				},
				{
					"name":"M28_Spy1422 glpF; glycerol uptake facilitator protein\tK02440 glpF; glycerol uptake facilitator"
				},
				{
					"name":"M28_Spy1561 glpF.2; aquaporin\tK02440 glpF; glycerol uptake facilitator"
				},
				{
					"name":"M28_Spy0699 glutathione S-transferase\tK00799 GST; glutathione S-transferase [EC:2.5.1.18]"
				},
				{
					"name":"M28_Spy1155 formate transporter\tK21993 fdhC; formate transporter"
				},
				{
					"name":"M28_Spy0577 mscL; large-conductance mechanosensitive channel\tK03282 mscL; large conductance mechanosensitive channel"
				},
				{
					"name":"M28_Spy1602 mechanosensitive ion channel\tK22044 ybiO; moderate conductance mechanosensitive channel"
				},
				{
					"name":"M28_Spy1538 corA; magnesium and cobalt transport protein\tK03284 corA; magnesium transporter"
				},
				{
					"name":"M28_Spy0306 hlyX; putative hemolysin\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"M28_Spy0781 srtA; lantibiotic\tK20482 nisA; lantibiotic bacteriocin"
				},
				{
					"name":"M28_Spy0634 czcD; cobalt-zinc-cadmium resistance protein\tK16264 czcD; cobalt-zinc-cadmium efflux system protein"
				},
				{
					"name":"M28_Spy1889 glucose uptake protein-like protein\tK05340 glcU; glucose uptake protein"
				},
				{
					"name":"M28_Spy0267 serine\/threonine sodium symporter\tK07862 sstT; serine\/threonine transporter"
				},
				{
					"name":"M28_Spy0269 potassium uptake protein KtrB\tK03498 trkH; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"M28_Spy0268 potassium uptake protein KtrA\tK03499 trkA; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"M28_Spy0620 pyrP; uracil permease\tK02824 uraA; uracil permease"
				},
				{
					"name":"M28_Spy0833 xanthine permease\tK16169 pbuX; xanthine permease"
				},
				{
					"name":"M28_Spy1466 guanine-hypoxanthine permease\tK06901 pbuG; adenine\/guanine\/hypoxanthine permease"
				},
				{
					"name":"M28_Spy0528 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"M28_Spy0813 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"M28_Spy1119 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"M28_Spy1432 sodium-dependent phosphate transporter\tK03324 yjbB; phosphate:Na+ symporter"
				},
				{
					"name":"M28_Spy1147 kup system potassium uptake protein\tK03549 kup; KUP system potassium uptake protein"
				},
				{
					"name":"M28_Spy0302 riboflavin transporter\tK23675 fmnP; riboflavin transporter"
				},
				{
					"name":"M28_Spy0478 thiamine transporter\tK16789 thiT; thiamine transporter"
				},
				{
					"name":"M28_Spy1156 hypothetical protein\tK16788 niaX; niacin transporter"
				},
				{
					"name":"M28_Spy0485 ftsW; cell division protein\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"M28_Spy1702 emm28 protein\tK03646 tolA; colicin import membrane protein"
				},
				{
					"name":"M28_Spy0870 oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0876 oadB; oxaloacetate decarboxylase beta chain\tK20509 madB; carboxybiotin decarboxylase [EC:7.2.4.1]"
				},
				{
					"name":"M28_Spy0867 oadA2; oxaloacetate decarboxylase alpha chain\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]"
				},
				{
					"name":"M28_Spy0882 oadA1; oxaloacetate decarboxylase alpha chain\tK01571 oadA; oxaloacetate decarboxylase (Na+ extruding) subunit alpha [EC:7.2.4.2]"
				},
				{
					"name":"M28_Spy0868 putative membrane associated protein\tK01573 oadG; oxaloacetate decarboxylase (Na+ extruding) subunit gamma"
				},
				{
					"name":"M28_Spy0869 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy0875 biotin carboxyl carrier protein of oxaloacetate decarboxylase\tK23351 gcdC; glutaconyl-CoA\/methylmalonyl-CoA decarboxylase subunit gamma"
				},
				{
					"name":"M28_Spy1288 ccdA; cytochrome c-type biogenesis protein\tK06196 ccdA; cytochrome c-type biogenesis protein"
				},
				{
					"name":"M28_Spy0625 periplasmic component of efflux system\tK24950 yknX; membrane fusion protein, antimicrobial resistance system"
				},
				{
					"name":"M28_Spy1712 periplasmic component of efflux system\tK24950 yknX; membrane fusion protein, antimicrobial resistance system"
				},
				{
					"name":"M28_Spy1067 nicotinamide mononucleotide transporter\tK03811 pnuC; nicotinamide mononucleotide transporter"
				}
				]
			},
			{
				"name":"02044 Secretion system [BR:spb02044]",
				"children":[
				{
					"name":"M28_Spy1185 integral membrane protein\tK02221 yggT; YggT family protein"
				},
				{
					"name":"M28_Spy1143 comEA; ComE operon protein 1\tK02237 comEA; competence protein ComEA"
				},
				{
					"name":"M28_Spy1535 comEB; ComE operon protein 2\tK01493 comEB; dCMP deaminase [EC:3.5.4.12]"
				},
				{
					"name":"M28_Spy1141 comEC.1; ComE operon protein 3\tK02238 comEC; competence protein ComEC"
				},
				{
					"name":"M28_Spy1368 comFA; ComF operon protein 1\tK02240 comFA; competence protein ComFA"
				},
				{
					"name":"M28_Spy1367 comFC; ComF operon protein 3\tK02242 comFC; competence protein ComFC"
				},
				{
					"name":"M28_Spy0084 comYA; competence protein ComYA\tK02243 comGA; competence protein ComGA"
				},
				{
					"name":"M28_Spy0085 comYB; competence protein ComYB\tK02244 comGB; competence protein ComGB"
				},
				{
					"name":"M28_Spy0086 comYC; competence protein ComYC\tK02245 comGC; competence protein ComGC"
				},
				{
					"name":"M28_Spy0087 competence protein ComYD\tK02246 comGD; competence protein ComGD"
				},
				{
					"name":"M28_Spy0089 comYF; competence protein ComYF\tK02248 comGF; competence protein ComGF"
				},
				{
					"name":"M28_Spy1199 prepilin peptidase family\tK02236 comC; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
				},
				{
					"name":"M28_Spy1524 secA; protein translocase subunit\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"M28_Spy1737 secE; protein translocase subunit\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"M28_Spy0401 secG; protein translocase subunit\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"M28_Spy0063 secY; protein translocase subunit\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"M28_Spy0887 ffh; signal recognition particle, subunit FFH\/SRP54\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"M28_Spy0453 ftsY; cell division protein\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"M28_Spy1665 yajC; protein translocase subunit\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"M28_Spy0202 hypothetical protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"M28_Spy0286 inner membrane protein\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				}
				]
			},
			{
				"name":"02042 Bacterial toxins [BR:spb02042]",
				"children":[
				{
					"name":"M28_Spy0337 spyA; C3 family ADP-ribosyltransferase\tK11044 spyA; C3 family ADP-ribosyltransferase [EC:2.4.2.-]"
				},
				{
					"name":"M28_Spy0700 putative exfoliative toxin\tK11041 eta; exfoliative toxin A\/B"
				},
				{
					"name":"M28_Spy0139 slo; streptolysin O\tK11031 slo; thiol-activated cytolysin"
				},
				{
					"name":"M28_Spy0306 hlyX; putative hemolysin\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"M28_Spy0953 cfa; cAMP factor\tK11045 cfa; cAMP factor"
				},
				{
					"name":"M28_Spy0540 sagA; streptolysin S precursor\tK11046 sagA; streptolysin S associated protein"
				},
				{
					"name":"M28_Spy0854 conserved membrane protein\tK11068 hlyIII; hemolysin III"
				},
				{
					"name":"M28_Spy0180 speG; exotoxin type G precursor\tK11040 se; staphylococcal enterotoxin"
				},
				{
					"name":"M28_Spy0345 speJ; exotoxin type J precursor\tK11040 se; staphylococcal enterotoxin"
				},
				{
					"name":"M28_Spy0969 speC; pyrogenic exotoxin SpeC\tK11040 se; staphylococcal enterotoxin"
				},
				{
					"name":"M28_Spy1223 speK; pyrogenic exotoxin SpeK\tK11040 se; staphylococcal enterotoxin"
				},
				{
					"name":"M28_Spy1687 smeZ; mitogenic exotoxin Z\tK11040 se; staphylococcal enterotoxin"
				},
				{
					"name":"M28_Spy1355 hyl; hyaluronoglucosaminidase\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
				}
				]
			},
			{
				"name":"02022 Two-component system [BR:spb02022]",
				"children":[
				{
					"name":"M28_Spy0424 vicK; two-component sensor histidine kinase\tK07652 vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0423 vicR; two-component response regulator\tK07668 vicR; two-component system, OmpR family, response regulator VicR"
				},
				{
					"name":"M28_Spy0919 ciaH; sensor protein\tK14982 ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0920 ciaR; transcriptional regulatory protein\tK14983 ciaR; two-component system, OmpR family, response regulator CiaR"
				},
				{
					"name":"M28_Spy0275 covS; CsrS\tK18940 arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0274 covR; TCS DNA-binding response regulator, control of virulence CovR\tK18941 arlR; two-component system, OmpR family, response regulator ArlR"
				},
				{
					"name":"M28_Spy1708 ihk; two component system histidine kinase\tK18986 ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1709 irr; two-component response regulator\tK18987 irr; two-component system, OmpR family, response regulator Irr"
				},
				{
					"name":"M28_Spy0780 srtK; sensor protein\tK20487 nisK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK\/SpaK [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0779 srtR; two-component response regulator\tK20488 nisR; two-component system, OmpR family, lantibiotic biosynthesis response regulator NisR\/SpaR"
				},
				{
					"name":"M28_Spy1374 yvqE; two-component sensor protein\tK11617 liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1373 yvqC; two-component response regulator\tK11618 liaR; two-component system, NarL family, response regulator LiaR"
				},
				{
					"name":"M28_Spy1616 sensory transduction protein kinase\tK14988 salK; two-component system, NarL family, secretion system sensor histidine kinase SalK"
				},
				{
					"name":"M28_Spy1615 salR; transcriptional regulatory protein\tK14989 salR; two-component system, NarL family, secretion system response regulator SalR"
				},
				{
					"name":"M28_Spy0808 dpiB; sensor kinase\tK02476 K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0807 dpiA; transcriptional regulatory protein\tK02475 K02475; two-component system, CitB family, response regulator"
				},
				{
					"name":"M28_Spy0198 fasB; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0199 fasC; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1359 rocA; sensory transduction protein kinase\tK07706 agrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0200 fasA; response regulator\tK07707 agrA; two-component system, LytTR family, response regulator AgrA"
				},
				{
					"name":"M28_Spy1218 yesM; two-component system sensor kinase YesM\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy1347 two-component sensor kinase\tK07718 yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
				},
				{
					"name":"M28_Spy0762 two-component response regulator\tK07720 yesN; two-component system, response regulator YesN"
				},
				{
					"name":"M28_Spy1346 two-component response regulator\tK07720 yesN; two-component system, response regulator YesN"
				}
				]
			},
			{
				"name":"02035 Bacterial motility proteins [BR:spb02035]",
				"children":[
				{
					"name":"M28_Spy0262 ABC transporter substrate-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				},
				{
					"name":"M28_Spy0686 cystine-binding protein\tK02424 tcyA; L-cystine transport system substrate-binding protein"
				}
				]
			},
			{
				"name":"03037 Cilium and associated proteins"
			},
			{
				"name":"04812 Cytoskeleton proteins [BR:spb04812]",
				"children":[
				{
					"name":"M28_Spy1188 ftsZ; cell division protein\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"M28_Spy1189 ftsA; cell division protein\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"M28_Spy1255 ParB-like protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"M28_Spy1899 parB; chromosome partitioning protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				}
				]
			},
			{
				"name":"04147 Exosome [BR:spb04147]",
				"children":[
				{
					"name":"M28_Spy0535 eno; enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"M28_Spy0227 plr; glyceraldehyde 3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"M28_Spy1591 pgk; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"M28_Spy0960 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"M28_Spy0360 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"M28_Spy1747 groEL; 60 kDa chaperonin\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"M28_Spy1487 dnaK; chaperone protein\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"M28_Spy0183 pgi; glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"M28_Spy1890 guaB; inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"M28_Spy0487 protein translation elongation factor Tu (EF-TU)\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"M28_Spy1461 hit; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical)\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"M28_Spy0847 ldh; L-lactate dehydrogenase\tK00016 LDH; L-lactate dehydrogenase [EC:1.1.1.27]"
				},
				{
					"name":"M28_Spy0117 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0420 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy1385 atoB; acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"M28_Spy0064 adk; adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"M28_Spy0708 apt; adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"M28_Spy1424 glpK; glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"M28_Spy1588 glnA; glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"M28_Spy0027 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"M28_Spy0734 acoL; dihydrolipoamide dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"M28_Spy0488 tpi; triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"M28_Spy1158 gpmA; phosphoglycerate mutase\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				}
				]
			},
			{
				"name":"02048 Prokaryotic defense system [BR:spb02048]",
				"children":[
				{
					"name":"M28_Spy0749 cas1; Type II CRISPR associated endonuclease, Cas1\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"M28_Spy1290 cas1; Type I-C CRISPR associated endonuclease, Cas1\tK15342 cas1; CRISP-associated protein Cas1"
				},
				{
					"name":"M28_Spy0750 cas2; Type II CRISPR associated endonuclease, Cas2\tK09951 cas2; CRISPR-associated protein Cas2"
				},
				{
					"name":"M28_Spy1289 cas2; CRISPR associated endonuclease Cas2\tK09951 cas2; CRISPR-associated protein Cas2"
				},
				{
					"name":"M28_Spy1295 cas3; CRISPR associated helicase-endonuclease Cas3\tK07012 cas3; CRISPR-associated endonuclease\/helicase Cas3 [EC:3.1.-.- 5.6.2.4]"
				},
				{
					"name":"M28_Spy1291 cas4; CRISPR associated protein Cas4\tK07464 cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]"
				},
				{
					"name":"M28_Spy1293 cas8c; Type I-C CRISPR associated protein Cas8c or Csd1\tK19117 csd1; CRISPR-associated protein Csd1"
				},
				{
					"name":"M28_Spy1292 cas7; Type I-C CRISPR associated protein Cas7 or Csd2\tK19118 csd2; CRISPR-associated protein Csd2"
				},
				{
					"name":"M28_Spy1294 cas5; Type I-C CRISPR associated protein Cas5\tK19119 cas5d; CRISPR-associated protein Cas5d"
				},
				{
					"name":"M28_Spy0748 cas9; Type II CRISPR RNA-guided endonuclease, Cas9\tK09952 csn1; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-]"
				},
				{
					"name":"M28_Spy0751 csn2; Type II CRISPR associated protein, Csn2\tK19137 csn2; CRISPR-associated protein Csn2"
				},
				{
					"name":"M28_Spy1610 hsdR; type I restriction-modification system restriction subunit\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]"
				},
				{
					"name":"M28_Spy1611 hsdS; type I restriction-modification system specificity subunit\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]"
				},
				{
					"name":"M28_Spy1612 hsdM; type I restriction-modification system methylation subunit\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]"
				},
				{
					"name":"M28_Spy0091 adenine-specific methyltransferase\tK00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]"
				},
				{
					"name":"M28_Spy0774 DNA-cytosine methyltransferase\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"M28_Spy1840 RelE-domain protein\tK06218 relE; mRNA interferase RelE\/StbE"
				},
				{
					"name":"M28_Spy1334 hypothetical protein\tK07473 dinJ; DNA-damage-inducible protein J"
				},
				{
					"name":"M28_Spy0778 srtI; SrtI\tK21498 higA-1; antitoxin HigA-1"
				},
				{
					"name":"M28_Spy1188 ftsZ; cell division protein\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"M28_Spy0692 parC; topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0691 parE; topoisomerase IV subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"M28_Spy0610 nifS1; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"M28_Spy0820 nifS2; cysteine desulfhydrase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"04030 G protein-coupled receptors"
			},
			{
				"name":"04050 Cytokine receptors"
			},
			{
				"name":"04054 Pattern recognition receptors"
			},
			{
				"name":"03310 Nuclear receptors"
			},
			{
				"name":"04040 Ion channels [BR:spb04040]"
			},
			{
				"name":"04031 GTP-binding proteins"
			},
			{
				"name":"04052 Cytokines and neuropeptides"
			},
			{
				"name":"04515 Cell adhesion molecules"
			},
			{
				"name":"04090 CD molecules [BR:spb04090]"
			},
			{
				"name":"01504 Antimicrobial resistance genes [BR:spb01504]",
				"children":[
				{
					"name":"M28_Spy1491 D-alanyl-D-alanine carboxypeptidase\tK07260 vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]"
				},
				{
					"name":"M28_Spy1054 dltA; D-alanine-activating enzyme\tK03367 dltA; D-alanine--poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1053 DltB\tK03739 dltB; membrane protein involved in D-alanine export"
				},
				{
					"name":"M28_Spy1052 D-alanyl carrier protein\tK14188 dltC; D-alanine--poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]"
				},
				{
					"name":"M28_Spy1051 dltD; protein precursor\tK03740 dltD; D-alanine transfer protein"
				}
				]
			},
			{
				"name":"00535 Proteoglycans"
			},
			{
				"name":"00536 Glycosaminoglycan binding proteins [BR:spb00536]",
				"children":[
				{
					"name":"M28_Spy1355 hyl; hyaluronoglucosaminidase\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
				}
				]
			},
			{
				"name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:spb00537]",
				"children":[
				{
					"name":"M28_Spy1355 hyl; hyaluronoglucosaminidase\tK01197 hya; hyaluronoglucosaminidase [EC:3.2.1.35]"
				}
				]
			},
			{
				"name":"04091 Lectins"
			},
			{
				"name":"04990 Domain-containing proteins not elsewhere classified"
			}
			]
		},
		{
			"name":"09185 Viral protein families",
			"children":[
			{
				"name":"03200 Viral proteins"
			},
			{
				"name":"03210 Viral fusion proteins"
			}
			]
		},
		{
			"name":"09184 RNA family",
			"children":[
			{
				"name":"03100 Non-coding RNAs [BR:spb03100]",
				"children":[
				{
					"name":"M28_SpyT0001 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0011 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0029 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0042 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0057 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0062 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"M28_SpyT0009 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0019 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0044 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0045 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0048 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0060 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0067 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"M28_SpyT0043 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0061 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0065 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"M28_SpyT0003 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0013 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0055 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"M28_SpyT0064 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"M28_SpyT0040 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"M28_SpyT0047 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"M28_SpyT0033 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0050 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0066 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"M28_SpyT0007 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0017 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0026 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0031 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"M28_SpyT0039 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"M28_SpyT0027 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0032 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0051 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"M28_SpyT0005 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0008 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0015 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0018 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0041 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0053 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0059 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"M28_SpyT0004 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0014 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0054 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0063 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"M28_SpyT0021 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0022 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0024 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0035 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"M28_SpyT0025 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"M28_SpyT0036 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"M28_SpyT0010 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"M28_SpyT0020 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"M28_SpyT0023 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0028 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0034 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0058 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"M28_SpyT0006 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0016 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0049 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0052 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"M28_SpyT0038 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"M28_SpyT0037 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"M28_SpyT0046 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"M28_SpyT0002 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0012 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0030 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyT0056 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"M28_SpyR0001 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0004 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0007 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0010 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0015 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0018 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0002 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0005 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0008 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0011 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0014 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0017 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0003 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0006 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0009 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0012 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0013 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_SpyR0016 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"M28_Spytm01 M28_Spytm01\tK15035 ssrA; transfer-messenger RNA"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"09190 Not Included in Pathway or Brite",
		"children":[
		{
			"name":"09191 Unclassified: metabolism",
			"children":[
			{
				"name":"99980 Enzymes with EC numbers",
				"children":[
				{
					"name":"M28_Spy0503 idnO; gluconate 5-dehydrogenase\tK00046 idnO; gluconate 5-dehydrogenase [EC:1.1.1.69]"
				},
				{
					"name":"M28_Spy0328 lctO; L-lactate oxidase\tK10530 lctO; L-lactate oxidase [EC:1.1.3.2]"
				},
				{
					"name":"M28_Spy0846 nox; NADH oxidase H2O-forming\tK17869 nox2; NADH oxidase (H2O-forming) [EC:1.6.3.4]"
				},
				{
					"name":"M28_Spy1753 ahpF; peroxiredoxin reductase (NAD(P)H)\tK03387 ahpF; NADH-dependent peroxiredoxin subunit F [EC:1.8.1.-]"
				},
				{
					"name":"M28_Spy0368 msrA.2; peptide methionine sulfoxide reductase\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]"
				},
				{
					"name":"M28_Spy1286 msrA; peptide methionine sulfoxide reductase\tK12267 msrAB; peptide methionine sulfoxide reductase msrA\/msrB [EC:1.8.4.11 1.8.4.12]"
				},
				{
					"name":"M28_Spy0755 msrB; peptide methionine sulfoxide reductase\tK07305 msrB; peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12]"
				},
				{
					"name":"M28_Spy1752 ahpC; peroxiredoxin reductase (NAD(P)H)\tK24119 ahpC; NADH-dependent peroxiredoxin subunit C [EC:1.11.1.26]"
				},
				{
					"name":"M28_Spy0638 trxB; thioredoxin reductase\tK21567 fnr; ferredoxin\/flavodoxin---NADP+ reductase [EC:1.18.1.2 1.19.1.1]"
				},
				{
					"name":"M28_Spy0677 arsC; arsenate reductase family protein\tK00537 arsC; arsenate reductase (glutaredoxin) [EC:1.20.4.1]"
				},
				{
					"name":"M28_Spy1773 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein\tK04068 nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]"
				},
				{
					"name":"M28_Spy0307 pflC; pyruvate formate-lyase activating enzyme\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"M28_Spy1736 pyruvate formate-lyase activating enzyme\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"M28_Spy1392 methyltransferase\tK07444 ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-]"
				},
				{
					"name":"M28_Spy0747 putative membrane spanning protein\tK27959 lit; lyso-form N-acyl lipoprotein transferase [EC:2.3.1.-]"
				},
				{
					"name":"M28_Spy0404 glutaminyl-peptide cyclotransferase\tK22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]"
				},
				{
					"name":"M28_Spy0435 glycosyltransferase\tK21349 ggs; glucosylglycerate synthase [EC:2.4.1.268]"
				},
				{
					"name":"M28_Spy0466 lgt; prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]"
				},
				{
					"name":"M28_Spy0834 apbE; thiamine biosynthesis lipoprotein\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]"
				},
				{
					"name":"M28_Spy1594 putative kinase\tK07030 fakA; fatty acid kinase [EC:2.7.2.18]"
				},
				{
					"name":"M28_Spy0740 putative membrane spanning protein\tK18672 dacA; diadenylate cyclase [EC:2.7.7.85]"
				},
				{
					"name":"M28_Spy0465 ptsK; hpr(ser) kinase\tK06023 hprK; HPr kinase\/phosphorylase [EC:2.7.11.- 2.7.4.-]"
				},
				{
					"name":"M28_Spy0727 estA; acetyl esterase\tK03930 estA; putative tributyrin esterase [EC:3.1.1.-]"
				},
				{
					"name":"M28_Spy1869 phosphoesterase, DHH family protein\tK22927 gdpP; cyclic-di-AMP phosphodiesterase [EC:3.1.4.59]"
				},
				{
					"name":"M28_Spy0214 tatD; sec-independent protein translocase protein\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"M28_Spy1669 dexB; glucan 1,6-alpha-glucosidase\tK01215 dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70]"
				},
				{
					"name":"M28_Spy0501 unsaturated glucuronyl hydrolase\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"M28_Spy0242 D-alanyl-D-alanine carboxypeptidase\tK01286 E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]"
				},
				{
					"name":"M28_Spy1672 ska; streptokinase\tK14745 ska; streptokinase A [EC:3.4.-.-]"
				},
				{
					"name":"M28_Spy0657 fms; peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"M28_Spy1657 def; peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"M28_Spy1111 peptidoglycan N-acetylglucosamine deacetylase\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]"
				},
				{
					"name":"M28_Spy0121 translation initiation inhibitor\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"M28_Spy0371 67 kDa myosin-crossreactive antigen\tK10254 ohyA; oleate hydratase [EC:4.2.1.53]"
				},
				{
					"name":"M28_Spy0736 hylA; hyaluronate lyase precursor\tK01727 hysA; hyaluronate lyase [EC:4.2.2.1]"
				},
				{
					"name":"M28_Spy0495 pacL; calcium-transporting ATPase\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]"
				},
				{
					"name":"M28_Spy1161 lead, cadmium, zinc and mercury transporting ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				}
				]
			},
			{
				"name":"99981 Carbohydrate metabolism"
			},
			{
				"name":"99982 Energy metabolism",
				"children":[
				{
					"name":"M28_Spy0595 ferredoxin\tK05337 fer; ferredoxin"
				},
				{
					"name":"M28_Spy0240 nifU; IscU\tK04488 iscU; nitrogen fixation protein NifU and related proteins"
				}
				]
			},
			{
				"name":"99983 Lipid metabolism",
				"children":[
				{
					"name":"M28_Spy0652 degV family protein\tK25232 fakB; fatty acid kinase fatty acid binding subunit"
				},
				{
					"name":"M28_Spy1165 DegV family protein\tK25232 fakB; fatty acid kinase fatty acid binding subunit"
				}
				]
			},
			{
				"name":"99984 Nucleotide metabolism",
				"children":[
				{
					"name":"M28_Spy0335 nrdI; nrdI\tK03647 nrdI; protein involved in ribonucleotide reduction"
				},
				{
					"name":"M28_Spy1676 NrdI.1\tK03647 nrdI; protein involved in ribonucleotide reduction"
				},
				{
					"name":"M28_Spy0564 DNA-entry nuclease\tK15051 endA; DNA-entry nuclease"
				},
				{
					"name":"M28_Spy0565 endA; DNA-entry nuclease\tK15051 endA; DNA-entry nuclease"
				},
				{
					"name":"M28_Spy0968 spd1; phage DNase Spd1\tK15051 endA; DNA-entry nuclease"
				},
				{
					"name":"M28_Spy1725 mf; mitogenic factor\tK15051 endA; DNA-entry nuclease"
				}
				]
			},
			{
				"name":"99985 Amino acid metabolism",
				"children":[
				{
					"name":"M28_Spy0850 lactoylglutathione lyase\tK08234 yaeR; glyoxylase I family protein"
				},
				{
					"name":"M28_Spy1187 pyridoxal-5'-phosphate family protein\tK06997 yggS; PLP dependent protein"
				}
				]
			},
			{
				"name":"99986 Glycan metabolism"
			},
			{
				"name":"99987 Cofactor metabolism"
			},
			{
				"name":"99988 Secondary metabolism"
			},
			{
				"name":"99999 Others"
			}
			]
		},
		{
			"name":"09192 Unclassified: genetic information processing",
			"children":[
			{
				"name":"99973 Transcription",
				"children":[
				{
					"name":"M28_Spy1751 csp; cold shock protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"M28_Spy1280 phage antirepressor protein\tK07741 antB; anti-repressor protein"
				},
				{
					"name":"M28_Spy0932 arsenate reductase family protein\tK16509 spxA; regulatory protein spx"
				},
				{
					"name":"M28_Spy1782 arsenate reductase family protein\tK16509 spxA; regulatory protein spx"
				},
				{
					"name":"M28_Spy0461 transcription accessory protein\tK06959 tex; protein Tex"
				}
				]
			},
			{
				"name":"99974 Translation",
				"children":[
				{
					"name":"M28_Spy1371 s1-type RNA-binding domain\tK07570 GSP13; general stress protein 13"
				}
				]
			},
			{
				"name":"99975 Protein processing",
				"children":[
				{
					"name":"M28_Spy1601 ropA; trigger factor, ppiase\tK03545 tig; trigger factor"
				},
				{
					"name":"M28_Spy0403 ssrA-binding protein\tK03664 smpB; SsrA-binding protein"
				},
				{
					"name":"M28_Spy1115 nrdH; glutaredoxin\tK06191 nrdH; glutaredoxin-like protein NrdH"
				},
				{
					"name":"M28_Spy0234 mecA; negative regulator of genetic competence\tK16511 mecA1_2; adapter protein MecA 1\/2"
				}
				]
			},
			{
				"name":"99976 Replication and repair",
				"children":[
				{
					"name":"M28_Spy0816 radC; DNA repair protein\tK03630 radC; DNA repair protein RadC"
				},
				{
					"name":"M28_Spy0220 rmuC family protein\tK09760 rmuC; DNA recombination protein RmuC"
				},
				{
					"name":"M28_Spy1146 hypothetical protein\tK07461 K07461; putative endonuclease"
				},
				{
					"name":"M28_Spy0858 smf; smf\tK04096 smf; DNA processing protein"
				},
				{
					"name":"M28_Spy0709 dnaD; phage protein\tK02086 dnaD; DNA replication protein"
				},
				{
					"name":"M28_Spy1321 transcriptional regulator, Cro\/CI family\tK07467 nicK; putative DNA relaxase"
				},
				{
					"name":"M28_Spy0998 phage terminase small subunit\tK07474 xtmA; phage terminase small subunit"
				},
				{
					"name":"M28_Spy0997 terminase large subunit\tK06909 xtmB; phage terminase large subunit"
				},
				{
					"name":"M28_Spy1684 ATPase, AAA family\tK07478 ycaJ; putative ATPase"
				},
				{
					"name":"M28_Spy1896 transposase\tK07482 K07482; transposase, IS30 family"
				},
				{
					"name":"M28_Spy0166 transposase\tK07483 K07483; transposase"
				},
				{
					"name":"M28_Spy0170 transposase\tK07483 K07483; transposase"
				},
				{
					"name":"M28_Spy0449 transposase\tK07483 K07483; transposase"
				},
				{
					"name":"M28_Spy1071 transposase\tK07483 K07483; transposase"
				},
				{
					"name":"M28_Spy0536 transposase\tK07486 K07486; transposase"
				},
				{
					"name":"M28_Spy0382 transposase\tK07493 K07493; putative transposase"
				},
				{
					"name":"M28_Spy0169 transposase\tK07497 K07497; putative transposase"
				},
				{
					"name":"M28_Spy0448 transposase\tK07497 K07497; putative transposase"
				},
				{
					"name":"M28_Spy1072 transposase\tK07497 K07497; putative transposase"
				}
				]
			},
			{
				"name":"99979 Viral proteins"
			},
			{
				"name":"99998 Others",
				"children":[
				{
					"name":"M28_Spy1568 putative cytosolic protein\tK09747 ebfC; nucleoid-associated protein EbfC"
				}
				]
			}
			]
		},
		{
			"name":"09193 Unclassified: signaling and cellular processes",
			"children":[
			{
				"name":"99977 Transport",
				"children":[
				{
					"name":"M28_Spy1400 amino acid permease\tK03293 TC.AAT; amino acid transporter, AAT family"
				},
				{
					"name":"M28_Spy0014 amino acid permease\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"M28_Spy0873 Mg2+\/citrate complex secondary transporter\tK03300 TC.CITMHS; citrate-Mg2+:H+ or citrate-Ca2+:H+ symporter, CitMHS family"
				},
				{
					"name":"M28_Spy0950 Na(+)-linked D-alanine glycine permease\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family"
				},
				{
					"name":"M28_Spy0266 braB; branched-chain amino acid transport system carrier protein\tK03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family"
				},
				{
					"name":"M28_Spy1579 nupC; nucleoside permease\tK03317 TC.CNT; concentrative nucleoside transporter, CNT family"
				}
				]
			},
			{
				"name":"99978 Cell growth",
				"children":[
				{
					"name":"M28_Spy1391 hypothetical protein\tK20073 mapZ; mid-cell-anchored protein Z"
				},
				{
					"name":"M28_Spy0203 Jag protein\tK06346 jag; spoIIIJ-associated protein"
				}
				]
			},
			{
				"name":"99993 Cell motility"
			},
			{
				"name":"99995 Signaling proteins",
				"children":[
				{
					"name":"M28_Spy1194 typA; GTP-binding protein TypA\/BipA\tK06207 typA; GTP-binding protein"
				},
				{
					"name":"M28_Spy0372 phoH; PhoH\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins"
				}
				]
			},
			{
				"name":"99992 Structural proteins"
			},
			{
				"name":"99994 Others",
				"children":[
				{
					"name":"M28_Spy0923 phoU; phosphate transport system protein\tK02039 phoU; phosphate transport system protein"
				},
				{
					"name":"M28_Spy0325 cutC; copper homeostasis protein\tK06201 cutC; copper homeostasis protein"
				}
				]
			}
			]
		},
		{
			"name":"09194 Poorly characterized",
			"children":[
			{
				"name":"99996 General function prediction only",
				"children":[
				{
					"name":"M28_Spy1775 putative oxidoreductase\tK03810 mviM; virulence factor"
				},
				{
					"name":"M28_Spy1131 putative competence protein\/transcription factor\tK06198 coiA; competence protein CoiA"
				},
				{
					"name":"M28_Spy0099 tRNA binding domain protein\tK06878 K06878; tRNA-binding protein"
				},
				{
					"name":"M28_Spy0475 hydrolase (HAD superfamily)\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"M28_Spy0241 ABC transporter-associated protein\tK09014 sufB; Fe-S cluster assembly protein SufB"
				},
				{
					"name":"M28_Spy0238 ABC transporter-associated protein\tK09015 sufD; Fe-S cluster assembly protein SufD"
				},
				{
					"name":"M28_Spy1094 ribonuclease BN\tK07058 K07058; membrane protein"
				},
				{
					"name":"M28_Spy0697 rhodanese-related sulfurtransferase\tK07146 K07146; UPF0176 protein"
				},
				{
					"name":"M28_Spy0271 lemA; lemA\tK03744 lemA; LemA protein"
				},
				{
					"name":"M28_Spy0463 zinc metalloprotease\tK03095 sprL; SprT-like protein"
				},
				{
					"name":"M28_Spy1838 phage protein\tK01421 yhgE; putative membrane protein"
				},
				{
					"name":"M28_Spy1832 integral membrane protein\tK08974 K08974; putative membrane protein"
				},
				{
					"name":"M28_Spy0458 putative membrane spanning protein\tK08986 ycgQ; putative membrane protein"
				},
				{
					"name":"M28_Spy0957 phnA; alkylphosphonate utilization operon functionally uncharacterized protein PhnA\tK06193 phnA; protein PhnA"
				}
				]
			},
			{
				"name":"99997 Function unknown",
				"children":[
				{
					"name":"M28_Spy0493 dGTP triphosphohydrolase\tK06885 K06885; uncharacterized protein"
				},
				{
					"name":"M28_Spy1598 alpha\/beta hydrolase\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"M28_Spy0290 integral membrane protein\tK06890 K06890; uncharacterized protein"
				},
				{
					"name":"M28_Spy0158 CoA binding protein\tK06929 K06929; uncharacterized protein"
				},
				{
					"name":"M28_Spy0289 hydrolase (HAD superfamily)\tK06950 K06950; uncharacterized protein"
				},
				{
					"name":"M28_Spy0630 RNA binding protein\tK06960 K06960; uncharacterized protein"
				},
				{
					"name":"M28_Spy1639 putative cytosolic protein\tK06962 K06962; uncharacterized protein"
				},
				{
					"name":"M28_Spy0549 endonuclease\/exonuclease\/phosphatase family protein\tK07004 K07004; uncharacterized protein"
				},
				{
					"name":"M28_Spy0633 putative cytosolic protein\tK07006 K07006; uncharacterized protein"
				},
				{
					"name":"M28_Spy0639 regulatory protein\tK07035 K07035; uncharacterized protein"
				},
				{
					"name":"M28_Spy0862 regulatory protein\tK07035 K07035; uncharacterized protein"
				},
				{
					"name":"M28_Spy0572 neutral zinc metallopeptidase family\tK07054 K07054; uncharacterized protein"
				},
				{
					"name":"M28_Spy0459 putative membrane spanning protein\tK07089 K07089; uncharacterized protein"
				},
				{
					"name":"M28_Spy0294 putative phosphoesterase\tK07095 K07095; uncharacterized protein"
				},
				{
					"name":"M28_Spy1157 transcriptional regulator, biotin repressor family\tK07105 K07105; uncharacterized protein"
				},
				{
					"name":"M28_Spy0706 short chain dehydrogenase\tK07124 K07124; uncharacterized protein"
				},
				{
					"name":"M28_Spy0304 Fe-S oxidoreductase\tK07139 K07139; uncharacterized protein"
				},
				{
					"name":"M28_Spy0300 putative cytosolic protein\tK08998 K08998; uncharacterized protein"
				},
				{
					"name":"M28_Spy1357 hypothetical protein\tK09704 K09704; uncharacterized protein"
				},
				{
					"name":"M28_Spy0888 ylxM; signal recognition particle associated protein\tK09787 K09787; uncharacterized protein"
				},
				{
					"name":"M28_Spy0367 s1 RNA binding domain\tK00243 K00243; uncharacterized protein"
				},
				{
					"name":"M28_Spy1772 yaaA; peroxide stress protein YaaA\tK09861 K09861; uncharacterized protein"
				},
				{
					"name":"M28_Spy1065 outer surface protein\tK09963 K09963; uncharacterized protein"
				},
				{
					"name":"M28_Spy0291 putative exported protein\tK09976 K09976; uncharacterized protein"
				},
				{
					"name":"M28_Spy0614 putative ribosome-associated protein\tK07584 ysxB; uncharacterized protein"
				},
				{
					"name":"M28_Spy1362 putative cytosolic protein\tK07586 ygaC; uncharacterized protein"
				},
				{
					"name":"M28_Spy1454 putative cytosolic protein\tK07742 ylxR; uncharacterized protein"
				}
				]
			}
			]
		}
		]
	}
	]
}