{
	"name":"spe02042",
	"children":[
	{
		"name":"Type III toxins: Intracellular toxins",
		"children":[
		{
			"name":"ADP-ribosyltransferase",
			"children":[
			{
				"name":"Diphtheria toxin (DT)"
			},
			{
				"name":"Cholera toxin\/Heat-labile enterotoxin"
			},
			{
				"name":"Exototoxin-A (ETA)"
			},
			{
				"name":"Exoenzyme S\/T"
			},
			{
				"name":"Pertussis toxin (PT)"
			},
			{
				"name":"ADP-ribosyltransferase toxin ArtA\/B"
			},
			{
				"name":"ADP-ribosyltransferase SpyA"
			}
			]
		},
		{
			"name":"Metalloprotease",
			"children":[
			{
				"name":"Botulinum neurotoxin (BoNT)"
			},
			{
				"name":"Tetanus toxin (TeTx)"
			},
			{
				"name":"Anthrax lethal toxin"
			}
			]
		},
		{
			"name":"Adenylate cyclase",
			"children":[
			{
				"name":"Anthrax edema toxin"
			},
			{
				"name":"Adenylate cyclase toxin (ACT)"
			},
			{
				"name":"Exoenzyme Y"
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Zona occludens toxin"
			},
			{
				"name":"Shiga toxin"
			},
			{
				"name":"Subtilase cytotoxin"
			},
			{
				"name":"Cytotoxic necrotizing factor 1\/Dermonecrotic toxin (DNT)"
			},
			{
				"name":"Enterotoxin ShET-1"
			},
			{
				"name":"Vacuolating cytotoxin"
			},
			{
				"name":"Cytolethal distending toxin"
			},
			{
				"name":"Exfoliative toxin type A"
			},
			{
				"name":"Toxin A\/B"
			},
			{
				"name":"Insecticidal toxin FitD\/Mcf"
			},
			{
				"name":"TccC-type insecticidal toxin",
				"children":[
				{
					"name":"Spro_0382 YD repeat protein\tK11021 tccC; insecticidal toxin complex protein TccC"
				}
				]
			},
			{
				"name":"Heat-stable enterotoxin"
			},
			{
				"name":"Typhoid toxin"
			}
			]
		}
		]
	},
	{
		"name":"Type II toxins: Membrane damaging toxins",
		"children":[
		{
			"name":"Pore-forming toxins, Beta-pore-forming\/Cholesterol-dependent"
		},
		{
			"name":"Pore-forming toxins, RTX"
		},
		{
			"name":"Pore-forming toxins, Other",
			"children":[
			{
				"name":"Spro_0457 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
			},
			{
				"name":"Spro_0849 protein of unknown function DUF21\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
			},
			{
				"name":"Spro_4482 filamentous haemagglutinin family outer membrane protein\tK11016 shlA; hemolysin"
			},
			{
				"name":"Spro_4481 Hemolysin activator HlyB domain protein\tK11017 shlB; hemolysin activation\/secretion protein"
			},
			{
				"name":"Spro_3900 channel protein, hemolysin III family\tK11068 hlyIII; hemolysin III"
			}
			]
		},
		{
			"name":"Toxins that enzymatically damage the membrane",
			"children":[
			{
				"name":"Spro_4198 Phospholipase C\tK01114 plc; phospholipase C [EC:3.1.4.3]"
			}
			]
		}
		]
	},
	{
		"name":"Type I toxins: Toxins that act from the cell surface",
		"children":[
		{
			"name":"Superantigens"
		}
		]
	},
	{
		"name":"Toxins that damage the extracellular matrix",
		"children":[
		{
			"name":"Hyaluronidases\/Collagenases"
		}
		]
	},
	{
		"name":"Not specified",
		"children":[
		{
			"name":"Ymt"
		},
		{
			"name":"Hydrogen cyanide production"
		},
		{
			"name":"Beta2 toxin"
		},
		{
			"name":"Enterotoxin"
		},
		{
			"name":"BteA"
		},
		{
			"name":"Superantigen-like protein"
		}
		]
	}
	]
}
