{
	"name":"sphz00001",
	"children":[
	{
		"name":"09100 Metabolism",
		"children":[
		{
			"name":"09101 Carbohydrate metabolism",
			"children":[
			{
				"name":"00010 Glycolysis \/ Gluconeogenesis [PATH:sphz00010]",
				"children":[
				{
					"name":"E3D81_16200 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_13405 fbaA; class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"E3D81_04915 triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"E3D81_06180 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_06735 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_15360 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_07490 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"E3D81_12970 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"E3D81_02810 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"E3D81_02780 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_00190 pyruvate dehydrogenase complex E1 component subunit beta\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_02775 pyruvate dehydrogenase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_13950 NAD(P)-dependent alcohol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_01845 aldehyde dehydrogenase\tK00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]"
				},
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_02935 galactose mutarotase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"E3D81_15455 galactose mutarotase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"E3D81_05015 HAD family phosphatase\tK20866 yihX; glucose-1-phosphatase [EC:3.1.3.10]"
				},
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_12185 pckA; phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				}
				]
			},
			{
				"name":"00020 Citrate cycle (TCA cycle) [PATH:sphz00020]",
				"children":[
				{
					"name":"E3D81_02050 citrate synthase\tK01647 CS; citrate synthase [EC:2.3.3.1]"
				},
				{
					"name":"E3D81_13880 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"E3D81_05605 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"E3D81_04215 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_04870 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_07005 2-oxoglutarate dehydrogenase E1 component\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]"
				},
				{
					"name":"E3D81_07010 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_07850 2-oxo acid dehydrogenase subunit E2\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_08000 sucD; succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_02390 sucC; ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_07975 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"E3D81_02495 fumarate reductase\/succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02500 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02490 succinate dehydrogenase cytochrome b subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"E3D81_14555 fumC; class II fumarate hydratase\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_13250 malate:quinone oxidoreductase\tK00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]"
				},
				{
					"name":"E3D81_12185 pckA; phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"E3D81_02780 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_00190 pyruvate dehydrogenase complex E1 component subunit beta\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_02775 pyruvate dehydrogenase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				}
				]
			},
			{
				"name":"00030 Pentose phosphate pathway [PATH:sphz00030]",
				"children":[
				{
					"name":"E3D81_16200 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"E3D81_08495 lactonase family protein\tK07404 pgl; 6-phosphogluconolactonase [EC:3.1.1.31]"
				},
				{
					"name":"E3D81_05610 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"E3D81_09965 transketolase family protein\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"E3D81_09970 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"E3D81_11830 fsa; fructose-6-phosphate aldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"E3D81_09135 rpiB; ribose 5-phosphate isomerase B\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_02010 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"E3D81_09340 bifunctional 4-hydroxy-2-oxoglutarate aldolase\/2-dehydro-3-deoxy-phosphogluconate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				},
				{
					"name":"E3D81_14395 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"E3D81_09345 sugar kinase\tK00874 kdgK; 2-dehydro-3-deoxygluconokinase [EC:2.7.1.45]"
				},
				{
					"name":"E3D81_13405 fbaA; class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				}
				]
			},
			{
				"name":"00040 Pentose and glucuronate interconversions [PATH:sphz00040]",
				"children":[
				{
					"name":"E3D81_00635 kduI; 5-dehydro-4-deoxy-D-glucuronate isomerase\tK01815 kduI; 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [EC:5.3.1.17]"
				},
				{
					"name":"E3D81_00625 SDR family oxidoreductase\tK00065 kduD; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase [EC:1.1.1.127]"
				},
				{
					"name":"E3D81_16530 uxaC; glucuronate isomerase\tK01812 uxaC; glucuronate isomerase [EC:5.3.1.12]"
				},
				{
					"name":"E3D81_06125 altronate dehydratase\tK01685 uxaA; altronate hydrolase [EC:4.2.1.7]"
				},
				{
					"name":"E3D81_09355 uxuA; mannonate dehydratase\tK01686 uxuA; mannonate dehydratase [EC:4.2.1.8]"
				},
				{
					"name":"E3D81_16055 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"E3D81_05610 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"E3D81_06080 ribulokinase\tK00853 araB; L-ribulokinase [EC:2.7.1.16]"
				},
				{
					"name":"E3D81_10985 carbohydrate kinase\tK22935 XK1; D-ribulokinase [EC:2.7.1.47]"
				},
				{
					"name":"E3D81_06090 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				}
				]
			},
			{
				"name":"00051 Fructose and mannose metabolism [PATH:sphz00051]",
				"children":[
				{
					"name":"E3D81_06940 glmM; phosphoglucosamine mutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"E3D81_16100 mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"E3D81_02540 gmd; GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"E3D81_01090 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]"
				},
				{
					"name":"E3D81_06090 L-fucose isomerase\tK01818 fucI; L-fucose\/D-arabinose isomerase [EC:5.3.1.25 5.3.1.3]"
				},
				{
					"name":"E3D81_06130 L-rhamnose mutarotase\tK29028 E5.1.3.29; L-fucose mutarotase [EC:5.1.3.29]"
				},
				{
					"name":"E3D81_06105 SDR family oxidoreductase\tK18333 E1.1.1.435; L-fucose dehydrogenase [EC:1.1.1.435]"
				},
				{
					"name":"E3D81_06110 amidohydrolase\tK07046 E3.1.1.120; L-fucono-1,5-lactonase [EC:3.1.1.120]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_13405 fbaA; class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"E3D81_04915 triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"E3D81_09135 rpiB; ribose 5-phosphate isomerase B\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				}
				]
			},
			{
				"name":"00052 Galactose metabolism [PATH:sphz00052]",
				"children":[
				{
					"name":"E3D81_02935 galactose mutarotase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"E3D81_15455 galactose mutarotase\tK01785 galM; aldose 1-epimerase [EC:5.1.3.3]"
				},
				{
					"name":"E3D81_15460 galK; galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"E3D81_15465 UDP-glucose--hexose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]"
				},
				{
					"name":"E3D81_15380 galE; UDP-glucose 4-epimerase GalE\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_08595 beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_10910 DUF4981 domain-containing protein\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_12890 DUF4968 domain-containing protein\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				}
				]
			},
			{
				"name":"00053 Ascorbate and aldarate metabolism [PATH:sphz00053]",
				"children":[
				{
					"name":"E3D81_16055 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"E3D81_14395 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00500 Starch and sucrose metabolism [PATH:sphz00500]",
				"children":[
				{
					"name":"E3D81_12890 DUF4968 domain-containing protein\tK01187 malZ; alpha-glucosidase [EC:3.2.1.20]"
				},
				{
					"name":"E3D81_04435 bglX; beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"E3D81_12905 glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				},
				{
					"name":"E3D81_09440 starch synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"E3D81_12900 glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"E3D81_12895 glgB; 1,4-alpha-glucan branching protein GlgB\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"E3D81_08050 glycoside hydrolase family 65 protein\tK00691 mapA; maltose phosphorylase [EC:2.4.1.8]"
				},
				{
					"name":"E3D81_08055 pgmB; beta-phosphoglucomutase\tK01838 pgmB; beta-phosphoglucomutase [EC:5.4.2.6]"
				},
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_16200 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				}
				]
			},
			{
				"name":"00620 Pyruvate metabolism [PATH:sphz00620]",
				"children":[
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_02780 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_00190 pyruvate dehydrogenase complex E1 component subunit beta\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_02775 pyruvate dehydrogenase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_13950 NAD(P)-dependent alcohol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"E3D81_02810 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"E3D81_04200 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_09150 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"E3D81_09145 accC; acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"E3D81_08370 acetyl-CoA carboxylase carboxyltransferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_14935 acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_01845 aldehyde dehydrogenase\tK00138 aldB; aldehyde dehydrogenase [EC:1.2.1.-]"
				},
				{
					"name":"E3D81_07975 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"E3D81_16485 MBL fold metallo-hydrolase\tK01069 gloB; hydroxyacylglutathione hydrolase [EC:3.1.2.6]"
				},
				{
					"name":"E3D81_01790 NADP-dependent malic enzyme\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_13250 malate:quinone oxidoreductase\tK00116 mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]"
				},
				{
					"name":"E3D81_14555 fumC; class II fumarate hydratase\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"E3D81_07430 phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"E3D81_12185 pckA; phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_02215 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00630 Glyoxylate and dicarboxylate metabolism [PATH:sphz00630]",
				"children":[
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_02050 citrate synthase\tK01647 CS; citrate synthase [EC:2.3.3.1]"
				},
				{
					"name":"E3D81_13880 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"E3D81_05605 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_13975 catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"E3D81_16940 gcvP; aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"E3D81_17025 gcvT; glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_00175 gcvH; glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"E3D81_06440 xylose isomerase\tK01816 hyi; hydroxypyruvate isomerase [EC:5.3.1.22]"
				},
				{
					"name":"E3D81_09340 bifunctional 4-hydroxy-2-oxoglutarate aldolase\/2-dehydro-3-deoxy-phosphogluconate aldolase\tK01625 eda; 2-dehydro-3-deoxyphosphogluconate aldolase \/ (4S)-4-hydroxy-2-oxoglutarate aldolase [EC:4.1.2.14 4.1.3.42]"
				}
				]
			},
			{
				"name":"00640 Propanoate metabolism [PATH:sphz00640]",
				"children":[
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_04200 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_09150 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"E3D81_09145 accC; acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"E3D81_08370 acetyl-CoA carboxylase carboxyltransferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_02390 sucC; ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_08000 sucD; succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_13880 prpC; 2-methylcitrate synthase\tK01659 prpC; 2-methylcitrate synthase [EC:2.3.3.5]"
				},
				{
					"name":"E3D81_13875 bifunctional 2-methylcitrate dehydratase\/aconitate hydratase\tK01720 prpD; 2-methylcitrate dehydratase [EC:4.2.1.79]"
				},
				{
					"name":"E3D81_05605 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"E3D81_13885 prpB; methylisocitrate lyase\tK03417 prpB; methylisocitrate lyase [EC:4.1.3.30]"
				},
				{
					"name":"E3D81_04180 methylglyoxal synthase\tK01734 mgsA; methylglyoxal synthase [EC:4.2.3.3]"
				}
				]
			},
			{
				"name":"00650 Butanoate metabolism [PATH:sphz00650]",
				"children":[
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_14685 3-hydroxyacyl-CoA dehydrogenase\/enoyl-CoA hydratase family protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_16225 enoyl-CoA hydratase\tK01715 crt; short-chain-enoyl-CoA hydratase [EC:4.2.1.150]"
				},
				{
					"name":"E3D81_04690 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"E3D81_02495 fumarate reductase\/succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02500 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02490 succinate dehydrogenase cytochrome b subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"E3D81_09775 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"E3D81_07975 succinate CoA transferase\tK18118 aarC; succinyl-CoA:acetate CoA-transferase [EC:2.8.3.18]"
				},
				{
					"name":"E3D81_00025 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"E3D81_02110 CoA transferase subunit A\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]"
				},
				{
					"name":"E3D81_02100 CoA transferase subunit B\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]"
				},
				{
					"name":"E3D81_02175 ilvB; biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02180 ilvN; acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				}
				]
			},
			{
				"name":"00660 C5-Branched dibasic acid metabolism [PATH:sphz00660]",
				"children":[
				{
					"name":"E3D81_02175 ilvB; biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02180 ilvN; acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02390 sucC; ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_08000 sucD; succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_02195 leuC; 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"E3D81_02200 leuD; 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"E3D81_02210 leuB; 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				}
				]
			},
			{
				"name":"00562 Inositol phosphate metabolism [PATH:sphz00562]",
				"children":[
				{
					"name":"E3D81_10890 phytase\tK01083 E3.1.3.8; 3-phytase [EC:3.1.3.8]"
				},
				{
					"name":"E3D81_13565 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"E3D81_04915 triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				}
				]
			},
			{
				"name":"00566 Sulfoquinovose metabolism",
				"children":[
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				}
				]
			}
			]
		},
		{
			"name":"09102 Energy metabolism",
			"children":[
			{
				"name":"00190 Oxidative phosphorylation [PATH:sphz00190]",
				"children":[
				{
					"name":"E3D81_09020 NADH-quinone oxidoreductase subunit A\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16300 NADH-quinone oxidoreductase subunit A\tK00330 nuoA; NADH-quinone oxidoreductase subunit A [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09025 NADH-quinone oxidoreductase subunit B\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16295 NADH-quinone oxidoreductase subunit B\tK00331 nuoB; NADH-quinone oxidoreductase subunit B [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_13370 NADH-quinone oxidoreductase subunit C\tK00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16290 NADH-quinone oxidoreductase subunit C\tK00332 nuoC; NADH-quinone oxidoreductase subunit C [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_13375 NADH-quinone oxidoreductase subunit D\tK00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16285 NADH-quinone oxidoreductase subunit D\tK00333 nuoD; NADH-quinone oxidoreductase subunit D [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16280 NAD(P)H-dependent oxidoreductase subunit E\tK00334 nuoE; NADH-quinone oxidoreductase subunit E [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16275 NADH oxidoreductase (quinone) subunit F\tK00335 nuoF; NADH-quinone oxidoreductase subunit F [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16270 2Fe-2S iron-sulfur cluster binding domain-containing protein\tK00336 nuoG; NADH-quinone oxidoreductase subunit G [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09615 NADH-quinone oxidoreductase subunit H\tK00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16265 nuoH; NADH-quinone oxidoreductase subunit NuoH\tK00337 nuoH; NADH-quinone oxidoreductase subunit H [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09610 4Fe-4S dicluster domain-containing protein\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16260 NADH-quinone oxidoreductase subunit I\tK00338 nuoI; NADH-quinone oxidoreductase subunit I [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16255 NADH-quinone oxidoreductase subunit J\tK00339 nuoJ; NADH-quinone oxidoreductase subunit J [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09600 nuoK; NADH-quinone oxidoreductase subunit NuoK\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16250 nuoK; NADH-quinone oxidoreductase subunit NuoK\tK00340 nuoK; NADH-quinone oxidoreductase subunit K [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09595 nuoL; NADH-quinone oxidoreductase subunit L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16245 nuoL; NADH-quinone oxidoreductase subunit L\tK00341 nuoL; NADH-quinone oxidoreductase subunit L [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09590 NADH-quinone oxidoreductase subunit M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16240 NADH-quinone oxidoreductase subunit M\tK00342 nuoM; NADH-quinone oxidoreductase subunit M [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_09585 NADH-quinone oxidoreductase subunit N\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_16235 NADH-quinone oxidoreductase subunit N\tK00343 nuoN; NADH-quinone oxidoreductase subunit N [EC:7.1.1.2]"
				},
				{
					"name":"E3D81_07170 NAD(P)\/FAD-dependent oxidoreductase\tK03885 ndh; NADH:quinone reductase (non-electrogenic) [EC:1.6.5.9]"
				},
				{
					"name":"E3D81_02495 fumarate reductase\/succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02500 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02490 succinate dehydrogenase cytochrome b subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"E3D81_08235 cyoE; protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"E3D81_08250 caa(3)-type oxidase\tK02277 coxD; cytochrome c oxidase subunit IV [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_08240 heme-copper oxidase subunit III\tK02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_08245 cytochrome oxidase subunit III\tK02276 coxC; cytochrome c oxidase subunit III [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_08225 cytochrome c oxidase subunit I\tK02274 coxA; cytochrome c oxidase subunit I [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_08220 cytochrome c oxidase subunit II\tK02275 coxB; cytochrome c oxidase subunit II [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_08230 heme A synthase\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"E3D81_11410 ccoN; cytochrome-c oxidase, cbb3-type subunit I\tK15862 ccoNO; cytochrome c oxidase cbb3-type subunit I\/II [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_11420 c-type cytochrome\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III"
				},
				{
					"name":"E3D81_09700 F0F1 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"E3D81_02155 F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"E3D81_09705 atpG; ATP synthase F1 subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"E3D81_09695 atpH; ATP synthase F1 subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"E3D81_02160 atpC; ATP synthase F1 subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"E3D81_09680 atpB; F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"E3D81_09690 F0F1 ATP synthase subunit B\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"E3D81_09685 atpE; ATP synthase F0 subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"E3D81_10780 inorganic diphosphatase\tK01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]"
				},
				{
					"name":"E3D81_10785 inorganic diphosphatase\tK01507 ppa; inorganic pyrophosphatase [EC:3.6.1.1]"
				},
				{
					"name":"E3D81_03955 ppk1; polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				}
				]
			},
			{
				"name":"00195 Photosynthesis"
			},
			{
				"name":"00196 Photosynthesis - antenna proteins"
			},
			{
				"name":"00710 Carbon fixation by Calvin cycle [PATH:sphz00710]",
				"children":[
				{
					"name":"E3D81_07490 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"E3D81_06180 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_06735 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_15360 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_13405 fbaA; class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_09965 transketolase family protein\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"E3D81_09970 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"E3D81_09135 rpiB; ribose 5-phosphate isomerase B\tK01808 rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]"
				},
				{
					"name":"E3D81_04915 triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"E3D81_05610 ribulose-phosphate 3-epimerase\tK01783 rpe; ribulose-phosphate 3-epimerase [EC:5.1.3.1]"
				},
				{
					"name":"E3D81_11830 fsa; fructose-6-phosphate aldolase\tK00616 TALDO1; transaldolase [EC:2.2.1.2]"
				},
				{
					"name":"E3D81_07430 phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"E3D81_12185 pckA; phosphoenolpyruvate carboxykinase (ATP)\tK01610 pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]"
				},
				{
					"name":"E3D81_01790 NADP-dependent malic enzyme\tK00029 maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				}
				]
			},
			{
				"name":"00720 Other carbon fixation pathways [PATH:sphz00720]",
				"children":[
				{
					"name":"E3D81_07430 phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_14555 fumC; class II fumarate hydratase\tK01679 E4.2.1.2B; fumarate hydratase, class II [EC:4.2.1.2]"
				},
				{
					"name":"E3D81_02495 fumarate reductase\/succinate dehydrogenase flavoprotein subunit\tK00239 sdhA; succinate dehydrogenase flavoprotein subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02500 succinate dehydrogenase\/fumarate reductase iron-sulfur subunit\tK00240 sdhB; succinate dehydrogenase iron-sulfur subunit [EC:1.3.5.1]"
				},
				{
					"name":"E3D81_02490 succinate dehydrogenase cytochrome b subunit\tK00241 sdhC; succinate dehydrogenase cytochrome b subunit"
				},
				{
					"name":"E3D81_08000 sucD; succinate--CoA ligase subunit alpha\tK01902 sucD; succinyl-CoA synthetase alpha subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_02390 sucC; ADP-forming succinate--CoA ligase subunit beta\tK01903 sucC; succinyl-CoA synthetase beta subunit [EC:6.2.1.5]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_04215 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_04870 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_05605 aconitate hydratase\tK27802 acnA; aconitate hydratase A \/ 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]"
				},
				{
					"name":"E3D81_04200 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_09150 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"E3D81_09145 accC; acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"E3D81_08370 acetyl-CoA carboxylase carboxyltransferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_04675 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase\/5,10-methylene-tetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"E3D81_14800 metF; methylenetetrahydrofolate reductase [NAD(P)H]\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				}
				]
			},
			{
				"name":"00680 Methane metabolism [PATH:sphz00680]",
				"children":[
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"E3D81_07430 phosphoenolpyruvate carboxylase\tK01595 ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_13405 fbaA; class II fructose-bisphosphate aldolase\tK01624 FBA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_12970 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"E3D81_03455 3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_08560 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_10975 hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_14990 phosphoserine phosphatase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_03450 serC; 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00910 Nitrogen metabolism [PATH:sphz00910]",
				"children":[
				{
					"name":"E3D81_16705 nosZ; Sec-dependent nitrous-oxide reductase\tK00376 nosZ; nitrous-oxide reductase [EC:1.7.2.4]"
				},
				{
					"name":"E3D81_05660 nitronate monooxygenase\tK00459 ncd2; nitronate monooxygenase [EC:1.13.12.16]"
				},
				{
					"name":"E3D81_17040 Glu\/Leu\/Phe\/Val dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"E3D81_03780 NADP-specific glutamate dehydrogenase\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_03055 gltB; glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"E3D81_03060 glutamate synthase subunit beta\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"E3D81_14775 carbonic anhydrase\tK01673 cynT; carbonic anhydrase [EC:4.2.1.1]"
				}
				]
			},
			{
				"name":"00920 Sulfur metabolism [PATH:sphz00920]",
				"children":[
				{
					"name":"E3D81_03690 GTP-binding protein\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_03685 cysD; sulfate adenylyltransferase subunit CysD\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_01895 bifunctional oligoribonuclease\/PAP phosphatase NrnA\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				},
				{
					"name":"E3D81_03680 phosphoadenylyl-sulfate reductase\tK00390 cysH; phosphoadenosine phosphosulfate reductase [EC:1.8.4.8 1.8.4.10]"
				},
				{
					"name":"E3D81_03665 HEPN domain-containing protein\tK00392 sir; sulfite reductase (ferredoxin) [EC:1.8.7.1]"
				},
				{
					"name":"E3D81_07610 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]"
				},
				{
					"name":"E3D81_03200 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"E3D81_07935 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"E3D81_11760 PLP-dependent cysteine synthase family protein\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"E3D81_06290 metX; homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]"
				},
				{
					"name":"E3D81_02335 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"09103 Lipid metabolism",
			"children":[
			{
				"name":"00061 Fatty acid biosynthesis [PATH:sphz00061]",
				"children":[
				{
					"name":"E3D81_04200 acetyl-CoA carboxylase carboxyltransferase subunit alpha\tK01962 accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_09150 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein\tK02160 accB; acetyl-CoA carboxylase biotin carboxyl carrier protein"
				},
				{
					"name":"E3D81_09145 accC; acetyl-CoA carboxylase biotin carboxylase subunit\tK01961 accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]"
				},
				{
					"name":"E3D81_08370 acetyl-CoA carboxylase carboxyltransferase subunit beta\tK01963 accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]"
				},
				{
					"name":"E3D81_02800 acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"E3D81_16390 fabD; ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"E3D81_09155 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_09715 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_12700 3-oxoacyl-ACP synthase III family protein\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_15965 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_02795 fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"E3D81_04715 SDR family NAD(P)-dependent oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_13245 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_15015 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\/3-hydroxyacyl-ACP dehydratase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"E3D81_04690 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"E3D81_07150 acyl-ACP desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				},
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				}
				]
			},
			{
				"name":"00062 Fatty acid elongation"
			},
			{
				"name":"00071 Fatty acid degradation [PATH:sphz00071]",
				"children":[
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_14685 3-hydroxyacyl-CoA dehydrogenase\/enoyl-CoA hydratase family protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"E3D81_09995 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_14510 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_16870 enoyl-CoA hydratase\/isomerase family protein\tK13238 ECI1; Delta3-Delta2-enoyl-CoA isomerase [EC:5.3.3.8]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00073 Cutin, suberine and wax biosynthesis"
			},
			{
				"name":"00074 Mycolic acid biosynthesis [PATH:sphz00074]",
				"children":[
				{
					"name":"E3D81_02800 acyl carrier protein\tK02078 acpP; acyl carrier protein"
				},
				{
					"name":"E3D81_16390 fabD; ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"E3D81_07150 acyl-ACP desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				}
				]
			},
			{
				"name":"00100 Steroid biosynthesis"
			},
			{
				"name":"00120 Primary bile acid biosynthesis"
			},
			{
				"name":"00121 Secondary bile acid biosynthesis"
			},
			{
				"name":"00140 Steroid hormone biosynthesis"
			},
			{
				"name":"00561 Glycerolipid metabolism [PATH:sphz00561]",
				"children":[
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_13950 NAD(P)-dependent alcohol dehydrogenase\tK13979 yahK; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
				},
				{
					"name":"E3D81_13740 glpK; glycerol kinase GlpK\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"E3D81_09160 plsX; phosphate acyltransferase PlsX\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"E3D81_12985 glycerol-3-phosphate 1-O-acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"E3D81_02565 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"E3D81_08885 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"E3D81_11995 glycosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				}
				]
			},
			{
				"name":"00564 Glycerophospholipid metabolism [PATH:sphz00564]",
				"children":[
				{
					"name":"E3D81_13670 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase\tK00057 gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]"
				},
				{
					"name":"E3D81_13745 glycerol-3-phosphate dehydrogenase\/oxidase\tK00111 glpA; glycerol-3-phosphate dehydrogenase [EC:1.1.5.3]"
				},
				{
					"name":"E3D81_12985 glycerol-3-phosphate 1-O-acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"E3D81_02565 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"E3D81_08885 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"E3D81_16050 glycerol-3-phosphate cytidylyltransferase\tK00980 tagD; glycerol-3-phosphate cytidylyltransferase [EC:2.7.7.39]"
				},
				{
					"name":"E3D81_13565 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				},
				{
					"name":"E3D81_07965 glycerophosphodiester phosphodiesterase family protein\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"E3D81_10995 glycerophosphodiester phosphodiesterase family protein\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"E3D81_11765 glycerophosphodiester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"E3D81_14650 glycerophosphodiester phosphodiesterase\tK01126 E3.1.4.46; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]"
				},
				{
					"name":"E3D81_00160 phosphatidate cytidylyltransferase\tK00981 E2.7.7.41; phosphatidate cytidylyltransferase [EC:2.7.7.41]"
				},
				{
					"name":"E3D81_07510 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]"
				},
				{
					"name":"E3D81_16450 phosphatidylserine decarboxylase family protein\tK01613 psd; phosphatidylserine decarboxylase [EC:4.1.1.65]"
				},
				{
					"name":"E3D81_11440 cls; cardiolipin synthase\tK06131 clsA_B; cardiolipin synthase A\/B [EC:2.7.8.-]"
				}
				]
			},
			{
				"name":"00565 Ether lipid metabolism",
				"children":[
				{
					"name":"E3D81_13565 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				}
				]
			},
			{
				"name":"00600 Sphingolipid metabolism [PATH:sphz00600]",
				"children":[
				{
					"name":"E3D81_01830 pyridoxal phosphate-dependent aminotransferase family protein\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"E3D81_01825 hypothetical protein\tK28560 bcerS; bacterial ceramide synthase [EC:2.3.1.-]"
				},
				{
					"name":"E3D81_01820 NAD(P)-dependent oxidoreductase\tK28561 cerR; ceramide reductase [EC:1.-.-.-]"
				},
				{
					"name":"E3D81_08325 glucosylceramidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"E3D81_08595 beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_10910 DUF4981 domain-containing protein\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_00305 sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00315 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00320 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_09360 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_08735 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_15090 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				}
				]
			},
			{
				"name":"00590 Arachidonic acid metabolism"
			},
			{
				"name":"00591 Linoleic acid metabolism"
			},
			{
				"name":"00592 alpha-Linolenic acid metabolism [PATH:sphz00592]",
				"children":[
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"01040 Biosynthesis of unsaturated fatty acids [PATH:sphz01040]",
				"children":[
				{
					"name":"E3D81_07150 acyl-ACP desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				},
				{
					"name":"E3D81_11960 arylesterase\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]"
				}
				]
			}
			]
		},
		{
			"name":"09104 Nucleotide metabolism",
			"children":[
			{
				"name":"00230 Purine metabolism [PATH:sphz00230]",
				"children":[
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_02010 ribose-phosphate pyrophosphokinase\tK00948 PRPS; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]"
				},
				{
					"name":"E3D81_06540 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"E3D81_16860 purD; phosphoribosylamine--glycine ligase\tK01945 purD; phosphoribosylamine---glycine ligase [EC:6.3.4.13]"
				},
				{
					"name":"E3D81_11045 purN; phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"E3D81_06810 purL; phosphoribosylformylglycinamidine synthase\tK01952 PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]"
				},
				{
					"name":"E3D81_11015 phosphoribosylformylglycinamidine cyclo-ligase\tK01933 purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]"
				},
				{
					"name":"E3D81_09030 5-(carboxyamino)imidazole ribonucleotide synthase\tK01589 purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]"
				},
				{
					"name":"E3D81_09035 purE; 5-(carboxyamino)imidazole ribonucleotide mutase\tK01588 purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]"
				},
				{
					"name":"E3D81_01725 phosphoribosylaminoimidazolesuccinocarboxamide synthase\tK01923 purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]"
				},
				{
					"name":"E3D81_09985 purB; adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"E3D81_11035 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"E3D81_12960 adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"E3D81_13340 twin-arginine translocation signal domain-containing protein\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"E3D81_17090 surE; 5'\/3'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"E3D81_01360 purine-nucleoside phosphorylase\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"E3D81_14850 hypoxanthine phosphoribosyltransferase\tK00760 hprT; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]"
				},
				{
					"name":"E3D81_06150 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"E3D81_15565 nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"E3D81_03065 non-canonical purine NTP diphosphatase\tK01519 rdgB; XTP\/dITP diphosphohydrolase [EC:3.6.1.66]"
				},
				{
					"name":"E3D81_05835 guaA; glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"E3D81_17100 guanylate kinase\tK00942 gmk; guanylate kinase [EC:2.7.4.8]"
				},
				{
					"name":"E3D81_02235 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_02230 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_16650 ribonucleoside triphosphate reductase\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"E3D81_02925 deoxyguanosinetriphosphate triphosphohydrolase\tK01129 dgt; dGTPase [EC:3.1.5.1]"
				},
				{
					"name":"E3D81_03880 bifunctional (p)ppGpp synthetase\/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"E3D81_07415 exopolyphosphatase\tK01524 ppx-gppA; exopolyphosphatase \/ guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]"
				},
				{
					"name":"E3D81_03890 adenylosuccinate synthase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"E3D81_04735 deoxynucleoside kinase\tK15519 dck; deoxyadenosine\/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]"
				},
				{
					"name":"E3D81_11160 AMP nucleosidase\tK01241 amn; AMP nucleosidase [EC:3.2.2.4]"
				},
				{
					"name":"E3D81_06200 adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"E3D81_03690 GTP-binding protein\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_03685 cysD; sulfate adenylyltransferase subunit CysD\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				}
				]
			},
			{
				"name":"00240 Pyrimidine metabolism [PATH:sphz00240]",
				"children":[
				{
					"name":"E3D81_08730 carB; carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_11115 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_01950 aspartate carbamoyltransferase catalytic subunit\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"E3D81_10585 dihydroorotase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"E3D81_12840 dihydroorotase\tK01465 URA4; dihydroorotase [EC:3.5.2.3]"
				},
				{
					"name":"E3D81_05780 quinone-dependent dihydroorotate dehydrogenase\tK00254 DHODH; dihydroorotate dehydrogenase [EC:1.3.5.2]"
				},
				{
					"name":"E3D81_13040 orotate phosphoribosyltransferase\tK00762 pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]"
				},
				{
					"name":"E3D81_06480 pyrF; orotidine-5'-phosphate decarboxylase\tK01591 pyrF; orotidine-5'-phosphate decarboxylase [EC:4.1.1.23]"
				},
				{
					"name":"E3D81_09050 UMP kinase\tK09903 pyrH; uridylate kinase [EC:2.7.4.22]"
				},
				{
					"name":"E3D81_15565 nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"E3D81_02830 maf; septum formation protein Maf\tK06287 yhdE; nucleoside triphosphate pyrophosphatase [EC:3.6.1.-]"
				},
				{
					"name":"E3D81_10010 CTP synthase\tK01937 pyrG; CTP synthase [EC:6.3.4.2]"
				},
				{
					"name":"E3D81_03555 (d)CMP kinase\tK00945 cmk; CMP\/dCMP kinase [EC:2.7.4.25]"
				},
				{
					"name":"E3D81_11230 uridine kinase\tK00876 udk; uridine kinase [EC:2.7.1.48]"
				},
				{
					"name":"E3D81_13340 twin-arginine translocation signal domain-containing protein\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"E3D81_17090 surE; 5'\/3'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"E3D81_07210 phosphorylase\tK00757 udp; uridine phosphorylase [EC:2.4.2.3]"
				},
				{
					"name":"E3D81_08790 uracil phosphoribosyltransferase\tK00761 upp; uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"E3D81_01955 pyrR; bifunctional pyr operon transcriptional regulator\/uracil phosphoribosyltransferase PyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"E3D81_09900 phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"E3D81_16650 ribonucleoside triphosphate reductase\tK21636 nrdD; ribonucleoside-triphosphate reductase (formate) [EC:1.1.98.6]"
				},
				{
					"name":"E3D81_16210 dCTP deaminase\tK01494 dcd; dCTP deaminase [EC:3.5.4.13]"
				},
				{
					"name":"E3D81_02235 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_02230 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_04735 deoxynucleoside kinase\tK15519 dck; deoxyadenosine\/deoxycytidine kinase [EC:2.7.1.76 2.7.1.74]"
				},
				{
					"name":"E3D81_10260 thymidine phosphorylase\tK00758 deoA; thymidine phosphorylase [EC:2.4.2.4]"
				},
				{
					"name":"E3D81_07550 thymidine kinase\tK00857 tdk; thymidine kinase [EC:2.7.1.21]"
				},
				{
					"name":"E3D81_11475 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"E3D81_07325 SDR family NAD(P)-dependent oxidoreductase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"09105 Amino acid metabolism",
			"children":[
			{
				"name":"00250 Alanine, aspartate and glutamate metabolism [PATH:sphz00250]",
				"children":[
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_00050 nadB; L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]"
				},
				{
					"name":"E3D81_00845 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]"
				},
				{
					"name":"E3D81_01910 type I asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"E3D81_08335 isoaspartyl peptidase\/L-asparaginase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"E3D81_03900 aspartate--ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"E3D81_06985 asparagine synthase B\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"E3D81_09480 amidohydrolase\tK13566 NIT2; omega-amidase [EC:3.5.1.3]"
				},
				{
					"name":"E3D81_15065 alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]"
				},
				{
					"name":"E3D81_02410 argG; argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"E3D81_02940 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"E3D81_03890 adenylosuccinate synthase\tK01939 purA; adenylosuccinate synthase [EC:6.3.4.4]"
				},
				{
					"name":"E3D81_09985 purB; adenylosuccinate lyase\tK01756 purB; adenylosuccinate lyase [EC:4.3.2.2]"
				},
				{
					"name":"E3D81_01950 aspartate carbamoyltransferase catalytic subunit\tK00609 pyrB; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]"
				},
				{
					"name":"E3D81_09775 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"E3D81_03055 gltB; glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"E3D81_03060 glutamate synthase subunit beta\tK00266 gltD; glutamate synthase (NADPH) small chain [EC:1.4.1.13]"
				},
				{
					"name":"E3D81_17040 Glu\/Leu\/Phe\/Val dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"E3D81_03780 NADP-specific glutamate dehydrogenase\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"E3D81_02460 pruA; L-glutamate gamma-semialdehyde dehydrogenase\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_08730 carB; carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_11115 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_11590 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"E3D81_06540 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				}
				]
			},
			{
				"name":"00260 Glycine, serine and threonine metabolism [PATH:sphz00260]",
				"children":[
				{
					"name":"E3D81_03460 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_13285 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_09910 thrA; bifunctional aspartate kinase\/homoserine dehydrogenase I\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"E3D81_01185 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"E3D81_06295 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"E3D81_09915 homoserine kinase\tK00872 thrB; homoserine kinase [EC:2.7.1.39]"
				},
				{
					"name":"E3D81_09920 thrC; threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				},
				{
					"name":"E3D81_12355 low specificity L-threonine aldolase\tK01620 ltaE; threonine aldolase [EC:4.1.2.48]"
				},
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"E3D81_12970 2,3-bisphosphoglycerate-independent phosphoglycerate mutase\tK15633 gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]"
				},
				{
					"name":"E3D81_03455 3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_08560 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_10975 hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_14990 phosphoserine phosphatase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_03450 serC; 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"E3D81_07325 SDR family NAD(P)-dependent oxidoreductase\tK16066 ydfG; 3-hydroxy acid dehydrogenase \/ malonic semialdehyde reductase [EC:1.1.1.381 1.1.1.-]"
				},
				{
					"name":"E3D81_00820 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"E3D81_16940 gcvP; aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"E3D81_17025 gcvT; glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_00175 gcvH; glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"E3D81_07510 pssA; CDP-diacylglycerol--serine O-phosphatidyltransferase\tK17103 CHO1; CDP-diacylglycerol---serine O-phosphatidyltransferase [EC:2.7.8.8]"
				},
				{
					"name":"E3D81_04295 cysteine synthase family protein\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_11165 pyridoxal-phosphate dependent enzyme\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_11270 cystathionine gamma-synthase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"E3D81_01240 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"E3D81_02220 ilvA; threonine ammonia-lyase IlvA\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"E3D81_08855 tryptophan synthase subunit alpha\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]"
				},
				{
					"name":"E3D81_08860 trpB; tryptophan synthase subunit beta\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				}
				]
			},
			{
				"name":"00270 Cysteine and methionine metabolism [PATH:sphz00270]",
				"children":[
				{
					"name":"E3D81_03200 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"E3D81_07935 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"E3D81_11760 PLP-dependent cysteine synthase family protein\tK01738 cysK; cysteine synthase [EC:2.5.1.47]"
				},
				{
					"name":"E3D81_11270 cystathionine gamma-synthase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"E3D81_04295 cysteine synthase family protein\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_11165 pyridoxal-phosphate dependent enzyme\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_08840 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"E3D81_16350 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"E3D81_13930 adenosylmethionine decarboxylase\tK01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]"
				},
				{
					"name":"E3D81_13915 polyamine aminopropyltransferase\tK00797 speE; spermidine synthase [EC:2.5.1.16]"
				},
				{
					"name":"E3D81_01780 GAF domain-containing protein\tK08968 msrC; L-methionine (R)-S-oxide reductase [EC:1.8.4.14]"
				},
				{
					"name":"E3D81_05185 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"E3D81_08765 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"E3D81_03460 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_13285 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_09910 thrA; bifunctional aspartate kinase\/homoserine dehydrogenase I\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"E3D81_01185 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"E3D81_06295 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"E3D81_09915 homoserine kinase\tK00872 thrB; homoserine kinase [EC:2.7.1.39]"
				},
				{
					"name":"E3D81_06290 metX; homoserine O-acetyltransferase\tK00641 metX; homoserine O-acetyltransferase\/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]"
				},
				{
					"name":"E3D81_06285 O-acetylhomoserine aminocarboxypropyltransferase\/cysteine synthase\tK01740 metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]"
				},
				{
					"name":"E3D81_02335 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK10764 metZ; O-succinylhomoserine sulfhydrylase [EC:2.5.1.-]"
				},
				{
					"name":"E3D81_02165 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03120 4-amino-4-deoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_08600 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_07610 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]"
				},
				{
					"name":"E3D81_11855 malate dehydrogenase\tK00024 mdh; malate dehydrogenase [EC:1.1.1.37]"
				},
				{
					"name":"E3D81_01240 L-serine ammonia-lyase\tK01752 E4.3.1.17; L-serine dehydratase [EC:4.3.1.17]"
				},
				{
					"name":"E3D81_07930 cysM; cysteine synthase CysM\tK12339 cysM; S-sulfo-L-cysteine synthase (O-acetyl-L-serine-dependent) [EC:2.5.1.144]"
				},
				{
					"name":"E3D81_03455 3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_08560 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_10975 hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_14990 phosphoserine phosphatase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_03450 serC; 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00280 Valine, leucine and isoleucine degradation [PATH:sphz00280]",
				"children":[
				{
					"name":"E3D81_02165 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03120 4-amino-4-deoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_08600 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_06895 Glu\/Leu\/Phe\/Val dehydrogenase\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"E3D81_13555 NAD(P)-dependent oxidoreductase\tK00020 HIBADH; 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_00035 acyl-CoA carboxylase subunit beta\tK01969 MCCC2; 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4]"
				},
				{
					"name":"E3D81_00025 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"E3D81_02110 CoA transferase subunit A\tK01028 scoA; 3-oxoacid CoA-transferase subunit A [EC:2.8.3.5]"
				},
				{
					"name":"E3D81_02100 CoA transferase subunit B\tK01029 scoB; 3-oxoacid CoA-transferase subunit B [EC:2.8.3.5]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00290 Valine, leucine and isoleucine biosynthesis [PATH:sphz00290]",
				"children":[
				{
					"name":"E3D81_02220 ilvA; threonine ammonia-lyase IlvA\tK01754 E4.3.1.19; threonine dehydratase [EC:4.3.1.19]"
				},
				{
					"name":"E3D81_02195 leuC; 3-isopropylmalate dehydratase large subunit\tK01703 leuC; 3-isopropylmalate\/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"E3D81_02200 leuD; 3-isopropylmalate dehydratase small subunit\tK01704 leuD; 3-isopropylmalate\/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]"
				},
				{
					"name":"E3D81_02210 leuB; 3-isopropylmalate dehydrogenase\tK00052 leuB; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]"
				},
				{
					"name":"E3D81_02175 ilvB; biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02180 ilvN; acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02190 ilvC; ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"E3D81_02170 ilvD; dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"E3D81_02165 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03120 4-amino-4-deoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_08600 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_06895 Glu\/Leu\/Phe\/Val dehydrogenase\tK00263 E1.4.1.9; leucine dehydrogenase [EC:1.4.1.9]"
				},
				{
					"name":"E3D81_02215 2-isopropylmalate synthase\tK01649 leuA; 2-isopropylmalate synthase [EC:2.3.3.13]"
				}
				]
			},
			{
				"name":"00300 Lysine biosynthesis [PATH:sphz00300]",
				"children":[
				{
					"name":"E3D81_06295 homoserine dehydrogenase\tK00003 hom; homoserine dehydrogenase [EC:1.1.1.3]"
				},
				{
					"name":"E3D81_03460 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_13285 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_09910 thrA; bifunctional aspartate kinase\/homoserine dehydrogenase I\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"E3D81_01185 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"E3D81_06275 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"E3D81_01410 dapB; 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				},
				{
					"name":"E3D81_08300 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase\tK00674 dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]"
				},
				{
					"name":"E3D81_02615 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"E3D81_01480 diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]"
				},
				{
					"name":"E3D81_13155 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"E3D81_03465 lysA; diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				},
				{
					"name":"E3D81_07765 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"E3D81_01025 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"E3D81_03980 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase\/alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				}
				]
			},
			{
				"name":"00310 Lysine degradation [PATH:sphz00310]",
				"children":[
				{
					"name":"E3D81_14515 aldehyde dehydrogenase family protein\tK26061 amaB; L-aminoadipate-semialdehyde dehydrogenase"
				},
				{
					"name":"E3D81_07010 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_07850 2-oxo acid dehydrogenase subunit E2\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_09995 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_14510 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_09775 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00220 Arginine biosynthesis [PATH:sphz00220]",
				"children":[
				{
					"name":"E3D81_02410 argG; argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"E3D81_02940 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_08730 carB; carbamoyl-phosphate synthase large subunit\tK01955 carB; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_11115 carA; glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit\tK01956 carA; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]"
				},
				{
					"name":"E3D81_17040 Glu\/Leu\/Phe\/Val dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"E3D81_03780 NADP-specific glutamate dehydrogenase\tK00262 E1.4.1.4; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_02605 argB; acetylglutamate kinase\tK00930 argB; acetylglutamate kinase [EC:2.7.2.8]"
				},
				{
					"name":"E3D81_02405 argC; N-acetyl-gamma-glutamyl-phosphate reductase\tK00145 argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]"
				},
				{
					"name":"E3D81_02615 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"E3D81_02595 M20\/M25\/M40 family metallo-hydrolase\tK01438 argE; acetylornithine deacetylase [EC:3.5.1.16]"
				}
				]
			},
			{
				"name":"00330 Arginine and proline metabolism [PATH:sphz00330]",
				"children":[
				{
					"name":"E3D81_06345 arginine decarboxylase\tK01585 speA; arginine decarboxylase [EC:4.1.1.19]"
				},
				{
					"name":"E3D81_03920 agmatine deiminase family protein\tK10536 aguA; agmatine deiminase [EC:3.5.3.12]"
				},
				{
					"name":"E3D81_03915 carbon-nitrogen hydrolase\tK12251 aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]"
				},
				{
					"name":"E3D81_13915 polyamine aminopropyltransferase\tK00797 speE; spermidine synthase [EC:2.5.1.16]"
				},
				{
					"name":"E3D81_13930 adenosylmethionine decarboxylase\tK01611 speD; S-adenosylmethionine decarboxylase [EC:4.1.1.50]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_02600 proC; pyrroline-5-carboxylate reductase\tK00286 proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]"
				},
				{
					"name":"E3D81_05575 proline dehydrogenase\tK00318 PRODH; proline dehydrogenase [EC:1.5.5.2]"
				},
				{
					"name":"E3D81_02460 pruA; L-glutamate gamma-semialdehyde dehydrogenase\tK00294 E1.2.1.88; 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88]"
				},
				{
					"name":"E3D81_01515 proB; glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"E3D81_01520 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				}
				]
			},
			{
				"name":"00340 Histidine metabolism [PATH:sphz00340]",
				"children":[
				{
					"name":"E3D81_12175 ATP phosphoribosyltransferase\tK00765 hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]"
				},
				{
					"name":"E3D81_01765 bifunctional phosphoribosyl-AMP cyclohydrolase\/phosphoribosyl-ATP diphosphatase HisIE\tK11755 hisIE; phosphoribosyl-AMP cyclohydrolase \/ phosphoribosyl-ATP pyrophosphohydrolase [EC:3.5.4.19 3.6.1.31]"
				},
				{
					"name":"E3D81_01755 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase\tK01814 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]"
				},
				{
					"name":"E3D81_01750 hisH; imidazole glycerol phosphate synthase subunit HisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]"
				},
				{
					"name":"E3D81_16005 hisH; imidazole glycerol phosphate synthase subunit HisH\tK02501 hisH; imidazole glycerol-phosphate synthase subunit HisH [EC:4.3.2.10]"
				},
				{
					"name":"E3D81_01760 hisF; imidazole glycerol phosphate synthase subunit HisF\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]"
				},
				{
					"name":"E3D81_16000 hisF; imidazole glycerol phosphate synthase subunit HisF\tK02500 hisF; imidazole glycerol-phosphate synthase subunit HisF [EC:4.3.2.10]"
				},
				{
					"name":"E3D81_01745 hisB; bifunctional histidinol-phosphatase\/imidazoleglycerol-phosphate dehydratase HisB\tK01089 hisB; imidazoleglycerol-phosphate dehydratase \/ histidinol-phosphatase [EC:4.2.1.19 3.1.3.15]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"E3D81_12170 hisD; histidinol dehydrogenase\tK00013 hisD; histidinol dehydrogenase [EC:1.1.1.23]"
				},
				{
					"name":"E3D81_07635 hutH; histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				},
				{
					"name":"E3D81_07625 urocanate hydratase\tK01712 hutU; urocanate hydratase [EC:4.2.1.49]"
				},
				{
					"name":"E3D81_07630 imidazolonepropionase\tK01468 hutI; imidazolonepropionase [EC:3.5.2.7]"
				},
				{
					"name":"E3D81_07620 hutG; formimidoylglutamase\tK01479 hutG; formiminoglutamase [EC:3.5.3.8]"
				},
				{
					"name":"E3D81_14980 arginase\tK01479 hutG; formiminoglutamase [EC:3.5.3.8]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00350 Tyrosine metabolism [PATH:sphz00350]",
				"children":[
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"E3D81_12305 hppD; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
				},
				{
					"name":"E3D81_12300 homogentisate 1,2-dioxygenase\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]"
				},
				{
					"name":"E3D81_09775 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				},
				{
					"name":"E3D81_15330 tryptophanase\tK01668 E4.1.99.2; tyrosine phenol-lyase [EC:4.1.99.2]"
				}
				]
			},
			{
				"name":"00360 Phenylalanine metabolism [PATH:sphz00360]",
				"children":[
				{
					"name":"E3D81_12285 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]"
				},
				{
					"name":"E3D81_12400 ferredoxin--NADP reductase\tK02613 paaE; ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"E3D81_12305 hppD; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
				},
				{
					"name":"E3D81_04855 katG; catalase\/peroxidase HPI\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]"
				}
				]
			},
			{
				"name":"00380 Tryptophan metabolism [PATH:sphz00380]",
				"children":[
				{
					"name":"E3D81_07010 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_07850 2-oxo acid dehydrogenase subunit E2\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_09995 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_14510 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_13975 catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"E3D81_04855 katG; catalase\/peroxidase HPI\tK03782 katG; catalase-peroxidase [EC:1.11.1.21]"
				}
				]
			},
			{
				"name":"00400 Phenylalanine, tyrosine and tryptophan biosynthesis [PATH:sphz00400]",
				"children":[
				{
					"name":"E3D81_05565 aroB; 3-dehydroquinate synthase\tK01735 aroB; 3-dehydroquinate synthase [EC:4.2.3.4]"
				},
				{
					"name":"E3D81_07100 aroQ; type II 3-dehydroquinate dehydratase\tK03786 aroQ; 3-dehydroquinate dehydratase II [EC:4.2.1.10]"
				},
				{
					"name":"E3D81_07960 shikimate kinase\tK00891 aroK; shikimate kinase [EC:2.7.1.71]"
				},
				{
					"name":"E3D81_07235 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase\tK00800 aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]"
				},
				{
					"name":"E3D81_07240 aroC; chorismate synthase\tK01736 aroC; chorismate synthase [EC:4.2.3.5]"
				},
				{
					"name":"E3D81_14910 anthranilate synthase component I family protein\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"E3D81_14915 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"E3D81_08870 trpD; anthranilate phosphoribosyltransferase\tK00766 trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]"
				},
				{
					"name":"E3D81_08865 phosphoribosylanthranilate isomerase\tK01817 trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]"
				},
				{
					"name":"E3D81_14920 trpC; indole-3-glycerol phosphate synthase TrpC\tK01609 trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]"
				},
				{
					"name":"E3D81_08855 tryptophan synthase subunit alpha\tK01695 trpA; tryptophan synthase alpha chain [EC:4.2.1.20]"
				},
				{
					"name":"E3D81_08860 trpB; tryptophan synthase subunit beta\tK01696 trpB; tryptophan synthase beta chain [EC:4.2.1.20]"
				},
				{
					"name":"E3D81_07230 3-deoxy-7-phosphoheptulonate synthase\tK04516 AROA1; chorismate mutase [EC:5.4.99.5]"
				},
				{
					"name":"E3D81_13150 prephenate dehydrogenase\tK04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]"
				},
				{
					"name":"E3D81_07225 prephenate dehydratase\tK04518 pheA2; prephenate dehydratase [EC:4.2.1.51]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"E3D81_12285 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]"
				}
				]
			}
			]
		},
		{
			"name":"09106 Metabolism of other amino acids",
			"children":[
			{
				"name":"00410 beta-Alanine metabolism [PATH:sphz00410]",
				"children":[
				{
					"name":"E3D81_04285 aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				},
				{
					"name":"E3D81_09430 aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				},
				{
					"name":"E3D81_09435 pantoate--beta-alanine ligase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				}
				]
			},
			{
				"name":"00430 Taurine and hypotaurine metabolism [PATH:sphz00430]",
				"children":[
				{
					"name":"E3D81_14970 ggt; gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"E3D81_15065 alanine dehydrogenase\tK00259 ald; alanine dehydrogenase [EC:1.4.1.1]"
				}
				]
			},
			{
				"name":"00440 Phosphonate and phosphinate metabolism",
				"children":[
				{
					"name":"E3D81_12870 MBL fold metallo-hydrolase\tK06167 phnP; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase [EC:3.1.4.55]"
				}
				]
			},
			{
				"name":"00450 Selenocompound metabolism [PATH:sphz00450]",
				"children":[
				{
					"name":"E3D81_08840 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase\tK00549 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:2.1.1.14]"
				},
				{
					"name":"E3D81_11270 cystathionine gamma-synthase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"E3D81_07145 cysteine desulfurase\tK11717 sufS; cysteine desulfurase \/ selenocysteine lyase [EC:2.8.1.7 4.4.1.16]"
				},
				{
					"name":"E3D81_07160 NAD(P)\/FAD-dependent oxidoreductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"E3D81_13075 trxB; thioredoxin-disulfide reductase\tK00384 trxB; thioredoxin reductase (NADPH) [EC:1.8.1.9]"
				},
				{
					"name":"E3D81_03690 GTP-binding protein\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_03685 cysD; sulfate adenylyltransferase subunit CysD\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_08275 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				}
				]
			},
			{
				"name":"00460 Cyanoamino acid metabolism [PATH:sphz00460]",
				"children":[
				{
					"name":"E3D81_04435 bglX; beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				},
				{
					"name":"E3D81_14970 ggt; gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"E3D81_01910 type I asparaginase\tK01424 E3.5.1.1; L-asparaginase [EC:3.5.1.1]"
				},
				{
					"name":"E3D81_08335 isoaspartyl peptidase\/L-asparaginase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"E3D81_03900 aspartate--ammonia ligase\tK01914 asnA; aspartate--ammonia ligase [EC:6.3.1.1]"
				},
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				}
				]
			},
			{
				"name":"00470 D-Amino acid metabolism [PATH:sphz00470]",
				"children":[
				{
					"name":"E3D81_03980 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase\/alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"E3D81_07575 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"E3D81_07120 murI; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"E3D81_07755 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"E3D81_03050 dipeptide epimerase\tK19802 ycjG; L-Ala-D\/L-Glu epimerase \/ N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]"
				},
				{
					"name":"E3D81_10615 dipeptide epimerase\tK19802 ycjG; L-Ala-D\/L-Glu epimerase \/ N-acetyl-D-glutamate racemase [EC:5.1.1.20 5.1.1.25]"
				},
				{
					"name":"E3D81_00845 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]"
				},
				{
					"name":"E3D81_01480 diaminopimelate epimerase\tK01778 dapF; diaminopimelate epimerase [EC:5.1.1.7]"
				},
				{
					"name":"E3D81_03465 lysA; diaminopimelate decarboxylase\tK01586 lysA; diaminopimelate decarboxylase [EC:4.1.1.20]"
				}
				]
			},
			{
				"name":"00480 Glutathione metabolism [PATH:sphz00480]",
				"children":[
				{
					"name":"E3D81_14970 ggt; gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"E3D81_06685 glutathione synthase\tK01920 gshB; glutathione synthase [EC:6.3.2.3]"
				},
				{
					"name":"E3D81_04215 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_04870 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_03870 glutathione peroxidase\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]"
				},
				{
					"name":"E3D81_07555 glutathione peroxidase\tK00432 gpx; glutathione peroxidase [EC:1.11.1.9]"
				},
				{
					"name":"E3D81_13915 polyamine aminopropyltransferase\tK00797 speE; spermidine synthase [EC:2.5.1.16]"
				}
				]
			}
			]
		},
		{
			"name":"09107 Glycan biosynthesis and metabolism",
			"children":[
			{
				"name":"00520 Amino sugar and nucleotide sugar metabolism [PATH:sphz00520]",
				"children":[
				{
					"name":"E3D81_00170 anhydro-N-acetylmuramic acid kinase\tK09001 anmK; anhydro-N-acetylmuramic acid kinase [EC:2.7.1.170]"
				},
				{
					"name":"E3D81_01350 murQ; N-acetylmuramic acid 6-phosphate etherase\tK07106 murQ; N-acetylmuramic acid 6-phosphate etherase [EC:4.2.1.126]"
				},
				{
					"name":"E3D81_09370 N-acylglucosamine 2-epimerase\tK01787 RENBP; N-acylglucosamine 2-epimerase [EC:5.1.3.8]"
				},
				{
					"name":"E3D81_07275 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"E3D81_07450 murB; UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"E3D81_01225 glycoside hydrolase family 3\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_08735 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_15090 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_01285 nagA; N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"E3D81_14435 nagA; N-acetylglucosamine-6-phosphate deacetylase\tK01443 nagA; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]"
				},
				{
					"name":"E3D81_14480 glucosamine-6-phosphate deaminase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"E3D81_16510 nagB; glucosamine-6-phosphate deaminase\tK02564 nagB; glucosamine-6-phosphate deaminase [EC:3.5.99.6]"
				},
				{
					"name":"E3D81_11590 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"E3D81_16200 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_16055 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"E3D81_15460 galK; galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"E3D81_15465 UDP-glucose--hexose-1-phosphate uridylyltransferase\tK00965 galT; UDPglucose--hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]"
				},
				{
					"name":"E3D81_15380 galE; UDP-glucose 4-epimerase GalE\tK01784 galE; UDP-glucose 4-epimerase [EC:5.1.3.2]"
				},
				{
					"name":"E3D81_06940 glmM; phosphoglucosamine mutase\tK01840 manB; phosphomannomutase [EC:5.4.2.8]"
				},
				{
					"name":"E3D81_16100 mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"E3D81_12905 glucose-1-phosphate adenylyltransferase\tK00975 glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]"
				},
				{
					"name":"E3D81_16075 rfbA; glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				}
				]
			},
			{
				"name":"00541 Biosynthesis of various nucleotide sugars [PATH:sphz00541]",
				"children":[
				{
					"name":"E3D81_16045 nucleotide sugar dehydrogenase\tK02474 wbpO; UDP-N-acetyl-D-glucosamine\/UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.136 1.1.1.-]"
				},
				{
					"name":"E3D81_15995 NAD-dependent epimerase\/dehydratase family protein\tK15894 pseB; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.115]"
				},
				{
					"name":"E3D81_15985 SDR family oxidoreductase\tK19068 wbjC; UDP-2-acetamido-2,6-beta-L-arabino-hexul-4-ose reductase [EC:1.1.1.367]"
				},
				{
					"name":"E3D81_15980 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)\tK24258 wbjD; UDP-N-acetyl-L-fucosamine synthase [EC:5.1.3.28]"
				},
				{
					"name":"E3D81_03575 KpsF\/GutQ family sugar-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]"
				},
				{
					"name":"E3D81_03585 3-deoxy-8-phosphooctulonate synthase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]"
				},
				{
					"name":"E3D81_02835 HAD-IIIA family hydrolase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]"
				},
				{
					"name":"E3D81_04740 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]"
				},
				{
					"name":"E3D81_00300 N-acetylneuraminate lyase\tK01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]"
				},
				{
					"name":"E3D81_09390 dihydrodipicolinate synthetase\tK01639 E4.1.3.3; N-acetylneuraminate lyase [EC:4.1.3.3]"
				},
				{
					"name":"E3D81_16055 nucleotide sugar dehydrogenase\tK00012 UGDH; UDPglucose 6-dehydrogenase [EC:1.1.1.22]"
				},
				{
					"name":"E3D81_16075 rfbA; glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"E3D81_15375 SDR family oxidoreductase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16090 rfbB; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16085 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"E3D81_08950 SDR family oxidoreductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"E3D81_16080 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"E3D81_16100 mannose-1-phosphate guanylyltransferase\tK00971 manC; mannose-1-phosphate guanylyltransferase [EC:2.7.7.13]"
				},
				{
					"name":"E3D81_02540 gmd; GDP-mannose 4,6-dehydratase\tK01711 gmd; GDPmannose 4,6-dehydratase [EC:4.2.1.47]"
				},
				{
					"name":"E3D81_01090 GDP-L-fucose synthase\tK02377 TSTA3; GDP-L-fucose synthase [EC:1.1.1.271]"
				}
				]
			},
			{
				"name":"00510 N-Glycan biosynthesis"
			},
			{
				"name":"00513 Various types of N-glycan biosynthesis"
			},
			{
				"name":"00512 Mucin type O-glycan biosynthesis"
			},
			{
				"name":"00515 Mannose type O-glycan biosynthesis"
			},
			{
				"name":"00514 Other types of O-glycan biosynthesis"
			},
			{
				"name":"00532 Glycosaminoglycan biosynthesis - chondroitin sulfate \/ dermatan sulfate"
			},
			{
				"name":"00534 Glycosaminoglycan biosynthesis - heparan sulfate \/ heparin"
			},
			{
				"name":"00533 Glycosaminoglycan biosynthesis - keratan sulfate"
			},
			{
				"name":"00531 Glycosaminoglycan degradation"
			},
			{
				"name":"00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
			},
			{
				"name":"00601 Glycosphingolipid biosynthesis - lacto and neolacto series"
			},
			{
				"name":"00603 Glycosphingolipid biosynthesis - globo and isoglobo series"
			},
			{
				"name":"00604 Glycosphingolipid biosynthesis - ganglio series"
			},
			{
				"name":"00511 Other glycan degradation [PATH:sphz00511]",
				"children":[
				{
					"name":"E3D81_00305 sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00315 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00320 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_09360 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_08595 beta-galactosidase\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_10910 DUF4981 domain-containing protein\tK01190 lacZ; beta-galactosidase [EC:3.2.1.23]"
				},
				{
					"name":"E3D81_08735 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_15090 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_14445 beta-N-acetylhexosaminidase\tK14459 HEX; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_02290 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_06670 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_08115 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_12035 alpha-1,3\/4-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_00610 glycoside hydrolase family 95 protein\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_02295 glycoside hydrolase family 95 protein\tK15923 AXY8; alpha-L-fucosidase 2 [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_10605 glycosylasparaginase\tK01444 AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]"
				},
				{
					"name":"E3D81_08325 glucosylceramidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				}
				]
			},
			{
				"name":"00540 Lipopolysaccharide biosynthesis [PATH:sphz00540]",
				"children":[
				{
					"name":"E3D81_15010 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"E3D81_15015 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\/3-hydroxyacyl-ACP dehydratase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"E3D81_15020 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]"
				},
				{
					"name":"E3D81_01610 UDP-2,3-diacylglucosamine diphosphatase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]"
				},
				{
					"name":"E3D81_03930 lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]"
				},
				{
					"name":"E3D81_17150 lpxK; tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]"
				},
				{
					"name":"E3D81_15370 3-deoxy-D-manno-octulosonic acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]"
				},
				{
					"name":"E3D81_06260 lauroyl acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				}
				]
			},
			{
				"name":"00542 O-Antigen repeat unit biosynthesis [PATH:sphz00542]",
				"children":[
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00550 Peptidoglycan biosynthesis [PATH:sphz00550]",
				"children":[
				{
					"name":"E3D81_07275 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"E3D81_07450 murB; UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"E3D81_07740 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"E3D81_07755 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"E3D81_07765 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"E3D81_07575 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"E3D81_01025 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"E3D81_03980 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase\/alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"E3D81_07380 isoprenyl transferase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"E3D81_03845 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"E3D81_07760 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"E3D81_07745 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"E3D81_08340 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_09455 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_12365 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_07750 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_07205 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_07200 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_07770 PASTA domain-containing protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_01795 dacB; D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"E3D81_05555 peptidase S13\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				}
				]
			},
			{
				"name":"00552 Teichoic acid biosynthesis [PATH:sphz00552]",
				"children":[
				{
					"name":"E3D81_03845 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"E3D81_11995 glycosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				}
				]
			},
			{
				"name":"00571 Lipoarabinomannan (LAM) biosynthesis"
			},
			{
				"name":"00572 Arabinogalactan biosynthesis - Mycobacterium",
				"children":[
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"00543 Exopolysaccharide biosynthesis [PATH:sphz00543]",
				"children":[
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"E3D81_03200 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				},
				{
					"name":"E3D81_07935 serine acetyltransferase\tK00640 cysE; serine O-acetyltransferase [EC:2.3.1.30]"
				}
				]
			}
			]
		},
		{
			"name":"09108 Metabolism of cofactors and vitamins",
			"children":[
			{
				"name":"00730 Thiamine metabolism [PATH:sphz00730]",
				"children":[
				{
					"name":"E3D81_05965 thiC; phosphomethylpyrimidine synthase ThiC\tK03147 thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]"
				},
				{
					"name":"E3D81_05770 thiD; bifunctional hydroxymethylpyrimidine kinase\/phosphomethylpyrimidine kinase\tK00941 thiD; hydroxymethylpyrimidine\/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]"
				},
				{
					"name":"E3D81_10860 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_13725 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_05985 thiH; 2-iminoacetate synthase ThiH\tK03150 thiH; 2-iminoacetate synthase [EC:4.1.99.19]"
				},
				{
					"name":"E3D81_00010 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]"
				},
				{
					"name":"E3D81_05980 thiazole synthase\tK03149 thiG; thiazole synthase [EC:2.8.1.10]"
				},
				{
					"name":"E3D81_05970 thiamine phosphate synthase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]"
				},
				{
					"name":"E3D81_05975 thiamine phosphate synthase\tK00788 thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]"
				},
				{
					"name":"E3D81_00040 thiL; thiamine-phosphate kinase\tK00946 thiL; thiamine-monophosphate kinase [EC:2.7.4.16]"
				},
				{
					"name":"E3D81_16435 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"E3D81_06200 adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				}
				]
			},
			{
				"name":"00740 Riboflavin metabolism [PATH:sphz00740]",
				"children":[
				{
					"name":"E3D81_09780 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase\/GTP cyclohydrolase II\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]"
				},
				{
					"name":"E3D81_12820 ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase\/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]"
				},
				{
					"name":"E3D81_15080 6,7-dimethyl-8-ribityllumazine synthase\tK00794 ribH; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]"
				},
				{
					"name":"E3D81_03515 riboflavin synthase\tK00793 ribE; riboflavin synthase [EC:2.5.1.9]"
				},
				{
					"name":"E3D81_03855 bifunctional riboflavin kinase\/FAD synthetase\tK11753 ribF; riboflavin kinase \/ FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]"
				},
				{
					"name":"E3D81_12835 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				}
				]
			},
			{
				"name":"00750 Vitamin B6 metabolism [PATH:sphz00750]",
				"children":[
				{
					"name":"E3D81_13365 pdxH; pyridoxamine 5'-phosphate oxidase\tK00275 pdxH; pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5]"
				},
				{
					"name":"E3D81_03450 serC; 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				},
				{
					"name":"E3D81_01420 pyridoxine 5'-phosphate synthase\tK03474 pdxJ; pyridoxine 5-phosphate synthase [EC:2.6.99.2]"
				},
				{
					"name":"E3D81_09920 thrC; threonine synthase\tK01733 thrC; threonine synthase [EC:4.2.3.1]"
				}
				]
			},
			{
				"name":"00760 Nicotinate and nicotinamide metabolism [PATH:sphz00760]",
				"children":[
				{
					"name":"E3D81_00050 nadB; L-aspartate oxidase\tK00278 nadB; L-aspartate oxidase [EC:1.4.3.16]"
				},
				{
					"name":"E3D81_00045 nadA; quinolinate synthase NadA\tK03517 nadA; quinolinate synthase [EC:2.5.1.72]"
				},
				{
					"name":"E3D81_12980 nadC; carboxylating nicotinate-nucleotide diphosphorylase\tK00767 nadC; nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19]"
				},
				{
					"name":"E3D81_10710 pncB; nicotinate phosphoribosyltransferase\tK00763 pncB; nicotinate phosphoribosyltransferase [EC:6.3.4.21]"
				},
				{
					"name":"E3D81_01360 purine-nucleoside phosphorylase\tK03783 punA; purine-nucleoside phosphorylase [EC:2.4.2.1]"
				},
				{
					"name":"E3D81_13340 twin-arginine translocation signal domain-containing protein\tK01081 E3.1.3.5; 5'-nucleotidase [EC:3.1.3.5]"
				},
				{
					"name":"E3D81_17090 surE; 5'\/3'-nucleotidase SurE\tK03787 surE; 5'\/3'-nucleotidase [EC:3.1.3.5 3.1.3.6]"
				},
				{
					"name":"E3D81_17095 nicotinate-nucleotide adenylyltransferase\tK00969 nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]"
				},
				{
					"name":"E3D81_09405 NAD+ synthase\tK01950 E6.3.5.1; NAD+ synthase (glutamine-hydrolysing) [EC:6.3.5.1]"
				},
				{
					"name":"E3D81_12545 nicotinamide-nucleotide amidohydrolase family protein\tK03743 pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]"
				},
				{
					"name":"E3D81_01210 pncA; bifunctional nicotinamidase\/pyrazinamidase\tK08281 pncA; nicotinamidase\/pyrazinamidase [EC:3.5.1.19 3.5.1.-]"
				},
				{
					"name":"E3D81_03770 NAD-dependent deacylase\tK12410 cobB; NAD-dependent protein deacetylase\/lipoamidase [EC:2.3.1.286 2.3.1.313]"
				},
				{
					"name":"E3D81_07375 NAD kinase\tK00858 ppnK; NAD+ kinase [EC:2.7.1.23]"
				},
				{
					"name":"E3D81_09775 NAD-dependent succinate-semialdehyde dehydrogenase\tK00135 gabD; succinate-semialdehyde dehydrogenase \/ glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]"
				}
				]
			},
			{
				"name":"00770 Pantothenate and CoA biosynthesis [PATH:sphz00770]",
				"children":[
				{
					"name":"E3D81_02175 ilvB; biosynthetic-type acetolactate synthase large subunit\tK01652 E2.2.1.6L; acetolactate synthase I\/II\/III large subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02180 ilvN; acetolactate synthase small subunit\tK01653 E2.2.1.6S; acetolactate synthase I\/III small subunit [EC:2.2.1.6]"
				},
				{
					"name":"E3D81_02190 ilvC; ketol-acid reductoisomerase\tK00053 ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]"
				},
				{
					"name":"E3D81_02170 ilvD; dihydroxy-acid dehydratase\tK01687 ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]"
				},
				{
					"name":"E3D81_06495 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase\tK00606 panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]"
				},
				{
					"name":"E3D81_09435 pantoate--beta-alanine ligase\tK01918 panC; pantoate--beta-alanine ligase [EC:6.3.2.1]"
				},
				{
					"name":"E3D81_04190 type I pantothenate kinase\tK00867 coaA; type I pantothenate kinase [EC:2.7.1.33]"
				},
				{
					"name":"E3D81_00775 coaBC; bifunctional phosphopantothenoylcysteine decarboxylase\/phosphopantothenate--cysteine ligase CoaBC\tK13038 coaBC; phosphopantothenoylcysteine decarboxylase \/ phosphopantothenate---cysteine ligase [EC:4.1.1.36 6.3.2.5]"
				},
				{
					"name":"E3D81_05485 coaD; pantetheine-phosphate adenylyltransferase\tK00954 E2.7.7.3A; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]"
				},
				{
					"name":"E3D81_06800 dephospho-CoA kinase\tK00859 coaE; dephospho-CoA kinase [EC:2.7.1.24]"
				},
				{
					"name":"E3D81_16215 4'-phosphopantetheinyl transferase superfamily protein\tK06133 LYS5; 4'-phosphopantetheinyl transferase [EC:2.7.8.-]"
				},
				{
					"name":"E3D81_02165 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03120 4-amino-4-deoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_08600 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_04285 aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				},
				{
					"name":"E3D81_09430 aspartate 1-decarboxylase\tK01579 panD; aspartate 1-decarboxylase [EC:4.1.1.11]"
				},
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00780 Biotin metabolism [PATH:sphz00780]",
				"children":[
				{
					"name":"E3D81_02795 fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"E3D81_04715 SDR family NAD(P)-dependent oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_13245 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_00680 pyridoxal phosphate-dependent aminotransferase family protein\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"E3D81_13810 pyridoxal phosphate-dependent aminotransferase family protein\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"E3D81_13825 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]"
				},
				{
					"name":"E3D81_13815 bioD; dethiobiotin synthase\tK01935 bioD; dethiobiotin synthetase [EC:6.3.3.3]"
				},
				{
					"name":"E3D81_13820 bioB; biotin synthase BioB\tK01012 bioB; biotin synthase [EC:2.8.1.6]"
				},
				{
					"name":"E3D81_01045 biotin--[acetyl-CoA-carboxylase] ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"E3D81_01830 pyridoxal phosphate-dependent aminotransferase family protein\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				}
				]
			},
			{
				"name":"00785 Lipoic acid metabolism [PATH:sphz00785]",
				"children":[
				{
					"name":"E3D81_01265 lipB; lipoyl(octanoyl) transferase LipB\tK03801 lipB; lipoyl(octanoyl) transferase [EC:2.3.1.181]"
				},
				{
					"name":"E3D81_08740 lipA; lipoyl synthase\tK03644 lipA; lipoyl synthase [EC:2.8.1.8]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02780 pdhA; pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha\tK00161 PDHA; pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_00190 pyruvate dehydrogenase complex E1 component subunit beta\tK00162 PDHB; pyruvate dehydrogenase E1 component subunit beta [EC:1.2.4.1]"
				},
				{
					"name":"E3D81_02775 pyruvate dehydrogenase\tK00627 DLAT; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase) [EC:2.3.1.12]"
				},
				{
					"name":"E3D81_07005 2-oxoglutarate dehydrogenase E1 component\tK00164 OGDH; 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2]"
				},
				{
					"name":"E3D81_07010 odhB; 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_07850 2-oxo acid dehydrogenase subunit E2\tK00658 DLST; 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61]"
				},
				{
					"name":"E3D81_16940 gcvP; aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"E3D81_17025 gcvT; glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"E3D81_00175 gcvH; glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein"
				}
				]
			},
			{
				"name":"00790 Folate biosynthesis [PATH:sphz00790]",
				"children":[
				{
					"name":"E3D81_00205 folE; GTP cyclohydrolase I FolE\tK01495 GCH1; GTP cyclohydrolase IA [EC:3.5.4.16]"
				},
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"E3D81_07065 folB; dihydroneopterin aldolase\tK01633 folB; 7,8-dihydroneopterin aldolase\/epimerase\/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]"
				},
				{
					"name":"E3D81_07500 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase\tK00950 folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]"
				},
				{
					"name":"E3D81_08285 folP; dihydropteroate synthase\tK00796 folP; dihydropteroate synthase [EC:2.5.1.15]"
				},
				{
					"name":"E3D81_11470 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"E3D81_01915 bifunctional folylpolyglutamate synthase\/dihydrofolate synthase\tK11754 folC; dihydrofolate synthase \/ folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]"
				},
				{
					"name":"E3D81_09780 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase\/GTP cyclohydrolase II\tK14652 ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase \/ GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]"
				},
				{
					"name":"E3D81_03895 anthranilate synthase component I family protein\tK01665 pabB; para-aminobenzoate synthetase component I [EC:2.6.1.85]"
				},
				{
					"name":"E3D81_00200 6-carboxytetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"E3D81_12285 aromatic amino acid hydroxylase\tK00500 phhA; phenylalanine-4-hydroxylase [EC:1.14.16.1]"
				},
				{
					"name":"E3D81_10915 7-carboxy-7-deazaguanine synthase QueE\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				}
				]
			},
			{
				"name":"00670 One carbon pool by folate [PATH:sphz00670]",
				"children":[
				{
					"name":"E3D81_11470 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"E3D81_04675 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase\/5,10-methylene-tetrahydrofolate cyclohydrolase\tK01491 folD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]"
				},
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"E3D81_11045 purN; phosphoribosylglycinamide formyltransferase\tK11175 purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]"
				},
				{
					"name":"E3D81_11035 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"E3D81_17025 gcvT; glycine cleavage system aminomethyltransferase GcvT\tK00605 gcvT; glycine cleavage system T protein (aminomethyltransferase) [EC:2.1.2.10]"
				},
				{
					"name":"E3D81_11475 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				},
				{
					"name":"E3D81_14800 metF; methylenetetrahydrofolate reductase [NAD(P)H]\tK00297 metF; methylenetetrahydrofolate reductase (NADH) [EC:1.5.1.54]"
				},
				{
					"name":"E3D81_14995 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"E3D81_16350 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"E3D81_08765 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"E3D81_16940 gcvP; aminomethyl-transferring glycine dehydrogenase\tK00281 GLDC; glycine cleavage system P protein (glycine dehydrogenase) [EC:1.4.4.2]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_00175 gcvH; glycine cleavage system protein GcvH\tK02437 gcvH; glycine cleavage system H protein"
				},
				{
					"name":"E3D81_04295 cysteine synthase family protein\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_11165 pyridoxal-phosphate dependent enzyme\tK01697 CBS; cystathionine beta-synthase [EC:4.2.1.22]"
				},
				{
					"name":"E3D81_11270 cystathionine gamma-synthase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				}
				]
			},
			{
				"name":"00830 Retinol metabolism"
			},
			{
				"name":"00860 Porphyrin metabolism [PATH:sphz00860]",
				"children":[
				{
					"name":"E3D81_01465 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"E3D81_02970 hemA; glutamyl-tRNA reductase\tK02492 hemA; glutamyl-tRNA reductase [EC:1.2.1.70]"
				},
				{
					"name":"E3D81_02395 hemL; glutamate-1-semialdehyde-2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]"
				},
				{
					"name":"E3D81_02980 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
				},
				{
					"name":"E3D81_02975 hemC; hydroxymethylbilane synthase\tK01749 hemC; hydroxymethylbilane synthase [EC:2.5.1.61]"
				},
				{
					"name":"E3D81_14835 uroporphyrinogen-III synthase\tK01719 hemD; uroporphyrinogen-III synthase [EC:4.2.1.75]"
				},
				{
					"name":"E3D81_09760 uroporphyrinogen decarboxylase\tK01599 hemE; uroporphyrinogen decarboxylase [EC:4.1.1.37]"
				},
				{
					"name":"E3D81_13675 hemF; oxygen-dependent coproporphyrinogen oxidase\tK00228 CPOX; coproporphyrinogen III oxidase [EC:1.3.3.3]"
				},
				{
					"name":"E3D81_11330 hemN; oxygen-independent coproporphyrinogen III oxidase\tK02495 hemN; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]"
				},
				{
					"name":"E3D81_09765 hemJ; protoporphyrinogen oxidase HemJ\tK08973 hemJ; protoporphyrinogen IX oxidase [EC:1.3.99.-]"
				},
				{
					"name":"E3D81_15555 ferrochelatase\tK01772 hemH; protoporphyrin\/coproporphyrin ferrochelatase [EC:4.98.1.1 4.99.1.9]"
				},
				{
					"name":"E3D81_03670 cobA; uroporphyrinogen-III C-methyltransferase\tK02303 cobA; uroporphyrin-III C-methyltransferase [EC:2.1.1.107]"
				},
				{
					"name":"E3D81_03675 bifunctional precorrin-2 dehydrogenase\/sirohydrochlorin ferrochelatase\tK24866 sirC; precorrin-2 dehydrogenase [EC:1.3.1.76]"
				},
				{
					"name":"E3D81_08235 cyoE; protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"E3D81_08230 heme A synthase\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				}
				]
			},
			{
				"name":"00130 Ubiquinone and other terpenoid-quinone biosynthesis [PATH:sphz00130]",
				"children":[
				{
					"name":"E3D81_03540 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]"
				},
				{
					"name":"E3D81_06990 UbiD family decarboxylase\tK03182 ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]"
				},
				{
					"name":"E3D81_12835 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				},
				{
					"name":"E3D81_07320 ubiE; bifunctional demethylmenaquinone methyltransferase\/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE\tK03183 ubiE; demethylmenaquinone methyltransferase \/ 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]"
				},
				{
					"name":"E3D81_01450 hotdog fold thioesterase\tK19222 menI; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase [EC:3.1.2.28]"
				},
				{
					"name":"E3D81_13180 radical SAM protein\tK11782 mqnA; chorismate dehydratase [EC:4.2.1.151]"
				},
				{
					"name":"E3D81_13170 mqnE; aminofutalosine synthase MqnE\tK18285 mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]"
				},
				{
					"name":"E3D81_14940 amidohydrolase\tK20810 mqnX; aminodeoxyfutalosine deaminase [EC:3.5.4.40]"
				},
				{
					"name":"E3D81_00195 mqnB; futalosine hydrolase\tK11783 mqnB; futalosine hydrolase [EC:3.2.2.26]"
				},
				{
					"name":"E3D81_13450 CofH family radical SAM protein\tK11784 mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]"
				},
				{
					"name":"E3D81_17080 1,4-dihydroxy-6-naphthoate synthase\tK11785 mqnD; 5,8-dihydroxy-2-naphthoate synthase [EC:4.1.99.29]"
				},
				{
					"name":"E3D81_12305 hppD; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
				}
				]
			}
			]
		},
		{
			"name":"09109 Metabolism of terpenoids and polyketides",
			"children":[
			{
				"name":"00900 Terpenoid backbone biosynthesis [PATH:sphz00900]",
				"children":[
				{
					"name":"E3D81_00010 1-deoxy-D-xylulose-5-phosphate synthase\tK01662 dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]"
				},
				{
					"name":"E3D81_11105 1-deoxy-D-xylulose-5-phosphate reductoisomerase\tK00099 dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]"
				},
				{
					"name":"E3D81_12880 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase\tK00991 ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]"
				},
				{
					"name":"E3D81_03785 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase\tK00919 ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]"
				},
				{
					"name":"E3D81_09445 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase\tK01770 ispF; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:4.6.1.12]"
				},
				{
					"name":"E3D81_09625 ispG; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase\tK03526 gcpE; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]"
				},
				{
					"name":"E3D81_15560 4-hydroxy-3-methylbut-2-enyl diphosphate reductase\tK03527 ispH; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_12835 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				},
				{
					"name":"E3D81_14230 isopentenyl-diphosphate Delta-isomerase\tK01823 idi; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]"
				},
				{
					"name":"E3D81_09475 polyprenyl synthetase family protein\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"E3D81_01635 polyprenyl synthetase family protein\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]"
				},
				{
					"name":"E3D81_07380 isoprenyl transferase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				}
				]
			},
			{
				"name":"00902 Monoterpenoid biosynthesis"
			},
			{
				"name":"00909 Sesquiterpenoid and triterpenoid biosynthesis"
			},
			{
				"name":"00904 Diterpenoid biosynthesis"
			},
			{
				"name":"00906 Carotenoid biosynthesis [PATH:sphz00906]",
				"children":[
				{
					"name":"E3D81_14250 phytoene\/squalene synthase family protein\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]"
				},
				{
					"name":"E3D81_14255 crtI; phytoene desaturase\tK10027 crtI; phytoene desaturase [EC:1.3.99.26 1.3.99.28 1.3.99.29 1.3.99.31]"
				},
				{
					"name":"E3D81_14240 beta-carotene hydroxylase\tK15746 crtZ; beta-carotene 3-hydroxylase [EC:1.14.15.24]"
				}
				]
			},
			{
				"name":"00905 Brassinosteroid biosynthesis"
			},
			{
				"name":"00981 Insect hormone biosynthesis"
			},
			{
				"name":"00908 Zeatin biosynthesis"
			},
			{
				"name":"00903 Limonene degradation",
				"children":[
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00907 Pinene, camphor and geraniol degradation [PATH:sphz00907]",
				"children":[
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_00025 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"01052 Type I polyketide structures"
			},
			{
				"name":"00522 Biosynthesis of 12-, 14- and 16-membered macrolides"
			},
			{
				"name":"01051 Biosynthesis of ansamycins",
				"children":[
				{
					"name":"E3D81_09965 transketolase family protein\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				},
				{
					"name":"E3D81_09970 transketolase\tK00615 E2.2.1.1; transketolase [EC:2.2.1.1]"
				}
				]
			},
			{
				"name":"01059 Biosynthesis of enediyne antibiotics"
			},
			{
				"name":"01056 Biosynthesis of type II polyketide backbone"
			},
			{
				"name":"01057 Biosynthesis of type II polyketide products"
			},
			{
				"name":"00253 Tetracycline biosynthesis"
			},
			{
				"name":"00523 Polyketide sugar unit biosynthesis [PATH:sphz00523]",
				"children":[
				{
					"name":"E3D81_16075 rfbA; glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"E3D81_15375 SDR family oxidoreductase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16090 rfbB; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16085 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"E3D81_08950 SDR family oxidoreductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"E3D81_16080 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"01054 Nonribosomal peptide structures [PATH:sphz01054]",
				"children":[
				{
					"name":"E3D81_00845 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]"
				}
				]
			},
			{
				"name":"01053 Biosynthesis of siderophore group nonribosomal peptides"
			},
			{
				"name":"01055 Biosynthesis of vancomycin group antibiotics",
				"children":[
				{
					"name":"E3D81_15375 SDR family oxidoreductase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16090 rfbB; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			}
			]
		},
		{
			"name":"09110 Biosynthesis of other secondary metabolites",
			"children":[
			{
				"name":"00940 Phenylpropanoid biosynthesis"
			},
			{
				"name":"00945 Stilbenoid, diarylheptanoid and gingerol biosynthesis"
			},
			{
				"name":"00941 Flavonoid biosynthesis"
			},
			{
				"name":"00944 Flavone and flavonol biosynthesis"
			},
			{
				"name":"00942 Anthocyanin biosynthesis"
			},
			{
				"name":"00943 Isoflavonoid biosynthesis"
			},
			{
				"name":"00946 Degradation of flavonoids [PATH:sphz00946]",
				"children":[
				{
					"name":"E3D81_04435 bglX; beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				}
				]
			},
			{
				"name":"00901 Indole alkaloid biosynthesis"
			},
			{
				"name":"00403 Indole diterpene alkaloid biosynthesis"
			},
			{
				"name":"00950 Isoquinoline alkaloid biosynthesis"
			},
			{
				"name":"00960 Tropane, piperidine and pyridine alkaloid biosynthesis"
			},
			{
				"name":"00996 Biosynthesis of various alkaloids [PATH:sphz00996]",
				"children":[
				{
					"name":"E3D81_00020 enoyl-CoA hydratase\/isomerase family protein\tK18383 ferB; feruloyl-CoA hydratase\/lyase [EC:4.1.2.61]"
				}
				]
			},
			{
				"name":"00232 Caffeine metabolism"
			},
			{
				"name":"00965 Betalain biosynthesis"
			},
			{
				"name":"00966 Glucosinolate biosynthesis"
			},
			{
				"name":"00402 Benzoxazinoid biosynthesis"
			},
			{
				"name":"00311 Penicillin and cephalosporin biosynthesis [PATH:sphz00311]",
				"children":[
				{
					"name":"E3D81_14400 acetylxylan esterase\tK01060 cah; cephalosporin-C deacetylase [EC:3.1.1.41]"
				},
				{
					"name":"E3D81_14365 bla; class A beta-lactamase\tK17836 penP; beta-lactamase class A [EC:3.5.2.6]"
				}
				]
			},
			{
				"name":"00332 Carbapenem biosynthesis [PATH:sphz00332]",
				"children":[
				{
					"name":"E3D81_01515 proB; glutamate 5-kinase\tK00931 proB; glutamate 5-kinase [EC:2.7.2.11]"
				},
				{
					"name":"E3D81_01520 glutamate-5-semialdehyde dehydrogenase\tK00147 proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]"
				}
				]
			},
			{
				"name":"00261 Monobactam biosynthesis [PATH:sphz00261]",
				"children":[
				{
					"name":"E3D81_03690 GTP-binding protein\tK00956 cysN; sulfate adenylyltransferase subunit 1 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_03685 cysD; sulfate adenylyltransferase subunit CysD\tK00957 cysD; sulfate adenylyltransferase subunit 2 [EC:2.7.7.4]"
				},
				{
					"name":"E3D81_03460 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_13285 aspartate kinase\tK00928 lysC; aspartate kinase [EC:2.7.2.4]"
				},
				{
					"name":"E3D81_09910 thrA; bifunctional aspartate kinase\/homoserine dehydrogenase I\tK12524 thrA; bifunctional aspartokinase \/ homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]"
				},
				{
					"name":"E3D81_01185 aspartate-semialdehyde dehydrogenase\tK00133 asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]"
				},
				{
					"name":"E3D81_06275 4-hydroxy-tetrahydrodipicolinate synthase\tK01714 dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]"
				},
				{
					"name":"E3D81_01410 dapB; 4-hydroxy-tetrahydrodipicolinate reductase\tK00215 dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]"
				}
				]
			},
			{
				"name":"00331 Clavulanic acid biosynthesis"
			},
			{
				"name":"00521 Streptomycin biosynthesis [PATH:sphz00521]",
				"children":[
				{
					"name":"E3D81_16885 phospho-sugar mutase\tK01835 pgm; phosphoglucomutase [EC:5.4.2.2]"
				},
				{
					"name":"E3D81_16075 rfbA; glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"E3D81_15375 SDR family oxidoreductase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16090 rfbB; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16085 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase\tK01790 rfbC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]"
				},
				{
					"name":"E3D81_08950 SDR family oxidoreductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				},
				{
					"name":"E3D81_16080 rfbD; dTDP-4-dehydrorhamnose reductase\tK00067 rfbD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]"
				}
				]
			},
			{
				"name":"00524 Neomycin, kanamycin and gentamicin biosynthesis"
			},
			{
				"name":"00525 Acarbose and validamycin biosynthesis [PATH:sphz00525]",
				"children":[
				{
					"name":"E3D81_16075 rfbA; glucose-1-phosphate thymidylyltransferase RfbA\tK00973 rfbA; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]"
				},
				{
					"name":"E3D81_15375 SDR family oxidoreductase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				},
				{
					"name":"E3D81_16090 rfbB; dTDP-glucose 4,6-dehydratase\tK01710 rfbB; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]"
				}
				]
			},
			{
				"name":"00401 Novobiocin biosynthesis [PATH:sphz00401]",
				"children":[
				{
					"name":"E3D81_13150 prephenate dehydrogenase\tK04517 tyrA2; prephenate dehydrogenase [EC:1.3.1.12]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				}
				]
			},
			{
				"name":"00404 Staurosporine biosynthesis"
			},
			{
				"name":"00405 Phenazine biosynthesis",
				"children":[
				{
					"name":"E3D81_14910 anthranilate synthase component I family protein\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"E3D81_14915 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				}
				]
			},
			{
				"name":"00333 Prodigiosin biosynthesis",
				"children":[
				{
					"name":"E3D81_16390 fabD; ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"E3D81_04715 SDR family NAD(P)-dependent oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_13245 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				}
				]
			},
			{
				"name":"00254 Aflatoxin biosynthesis"
			},
			{
				"name":"00975 Biosynthesis of various siderophores"
			},
			{
				"name":"00998 Biosynthesis of various antibiotics",
				"children":[
				{
					"name":"E3D81_02800 acyl carrier protein\tK02078 acpP; acyl carrier protein"
				}
				]
			},
			{
				"name":"00999 Biosynthesis of various plant secondary metabolites [PATH:sphz00999]",
				"children":[
				{
					"name":"E3D81_16350 methionine adenosyltransferase\tK00789 metK; S-adenosylmethionine synthetase [EC:2.5.1.6]"
				},
				{
					"name":"E3D81_04435 bglX; beta-glucosidase BglX\tK05349 bglX; beta-glucosidase [EC:3.2.1.21]"
				}
				]
			},
			{
				"name":"00997 Biosynthesis of various other secondary metabolites"
			}
			]
		},
		{
			"name":"09111 Xenobiotics biodegradation and metabolism",
			"children":[
			{
				"name":"00362 Benzoate degradation [PATH:sphz00362]",
				"children":[
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				},
				{
					"name":"E3D81_04340 carboxymuconolactone decarboxylase\tK01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]"
				},
				{
					"name":"E3D81_05050 carboxymuconolactone decarboxylase\tK01607 pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				},
				{
					"name":"E3D81_14685 3-hydroxyacyl-CoA dehydrogenase\/enoyl-CoA hydratase family protein\tK07516 fadN; 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35]"
				},
				{
					"name":"E3D81_09995 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_14510 acyl-CoA dehydrogenase\tK00252 GCDH; glutaryl-CoA dehydrogenase [EC:1.3.8.6]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				}
				]
			},
			{
				"name":"00627 Aminobenzoate degradation [PATH:sphz00627]",
				"children":[
				{
					"name":"E3D81_14935 acylphosphatase\tK01512 acyP; acylphosphatase [EC:3.6.1.7]"
				},
				{
					"name":"E3D81_12835 UbiX family flavin prenyltransferase\tK03186 ubiX; flavin prenyltransferase [EC:2.5.1.129]"
				},
				{
					"name":"E3D81_00020 enoyl-CoA hydratase\/isomerase family protein\tK18383 ferB; feruloyl-CoA hydratase\/lyase [EC:4.1.2.61]"
				}
				]
			},
			{
				"name":"00364 Fluorobenzoate degradation"
			},
			{
				"name":"00625 Chloroalkane and chloroalkene degradation [PATH:sphz00625]",
				"children":[
				{
					"name":"E3D81_00835 aldehyde dehydrogenase family protein\tK00128 ALDH; aldehyde dehydrogenase (NAD+) [EC:1.2.1.3]"
				}
				]
			},
			{
				"name":"00361 Chlorocyclohexane and chlorobenzene degradation"
			},
			{
				"name":"00623 Toluene degradation"
			},
			{
				"name":"00622 Xylene degradation"
			},
			{
				"name":"00633 Nitrotoluene degradation"
			},
			{
				"name":"00642 Ethylbenzene degradation",
				"children":[
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"00643 Styrene degradation",
				"children":[
				{
					"name":"E3D81_12300 homogentisate 1,2-dioxygenase\tK00451 HGD; homogentisate 1,2-dioxygenase [EC:1.13.11.5]"
				}
				]
			},
			{
				"name":"00791 Atrazine degradation"
			},
			{
				"name":"00930 Caprolactam degradation [PATH:sphz00930]",
				"children":[
				{
					"name":"E3D81_14395 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"E3D81_13870 3-hydroxybutyryl-CoA epimerase\tK01782 fadJ; 3-hydroxyacyl-CoA dehydrogenase \/ enoyl-CoA hydratase \/ 3-hydroxybutyryl-CoA epimerase [EC:1.1.1.35 4.2.1.17 5.1.2.3]"
				}
				]
			},
			{
				"name":"00363 Bisphenol degradation"
			},
			{
				"name":"00621 Dioxin degradation"
			},
			{
				"name":"00626 Naphthalene degradation"
			},
			{
				"name":"00624 Polycyclic aromatic hydrocarbon degradation"
			},
			{
				"name":"00365 Furfural degradation"
			},
			{
				"name":"00984 Steroid degradation [PATH:sphz00984]",
				"children":[
				{
					"name":"E3D81_14695 acetyl-CoA C-acyltransferase\tK00632 fadA; acetyl-CoA acyltransferase [EC:2.3.1.16]"
				}
				]
			},
			{
				"name":"00980 Metabolism of xenobiotics by cytochrome P450"
			},
			{
				"name":"00982 Drug metabolism - cytochrome P450"
			},
			{
				"name":"00983 Drug metabolism - other enzymes"
			}
			]
		},
		{
			"name":"09112 Not included in regular maps",
			"children":[
			{
				"name":"09113 Global maps only"
			}
			]
		}
		]
	},
	{
		"name":"09120 Genetic Information Processing",
		"children":[
		{
			"name":"09121 Transcription",
			"children":[
			{
				"name":"03020 RNA polymerase [PATH:sphz03020]",
				"children":[
				{
					"name":"E3D81_09325 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_09330 rpoC; DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_02625 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				}
				]
			},
			{
				"name":"03022 Basal transcription factors"
			},
			{
				"name":"03040 Spliceosome"
			}
			]
		},
		{
			"name":"09122 Translation",
			"children":[
			{
				"name":"03010 Ribosome [PATH:sphz03010]",
				"children":[
				{
					"name":"E3D81_00740 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_11365 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_00755 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_11380 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_00760 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_03070 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_08105 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_11385 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_07605 30S ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"E3D81_09860 rpsB; 30S ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"E3D81_02730 rpsC; 30S ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"E3D81_02630 rpsD; 30S ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"E3D81_02675 30S ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"E3D81_04250 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"E3D81_11810 rpsG; 30S ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"E3D81_02690 rpsH; 30S ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"E3D81_09865 rpsI; 30S ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"E3D81_11800 rpsJ; 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"E3D81_02635 rpsK; 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"E3D81_11815 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"E3D81_02640 rpsM; 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"E3D81_02695 rpsN; 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"E3D81_08140 rpsO; 30S ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"E3D81_14810 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"E3D81_02715 rpsQ; 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"E3D81_04255 rpsR; 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"E3D81_02740 rpsS; 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"E3D81_07990 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"E3D81_05010 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"E3D81_09310 50S ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"E3D81_02745 rplB; 50S ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"E3D81_02760 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"E3D81_02755 rplD; 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"E3D81_02700 rplE; 50S ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"E3D81_02685 50S ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"E3D81_04260 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"E3D81_09315 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"E3D81_09305 rplK; 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"E3D81_09320 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"E3D81_09870 rplM; 50S ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"E3D81_02710 rplN; 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"E3D81_02665 50S ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"E3D81_02725 rplP; 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"E3D81_02620 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"E3D81_02680 50S ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"E3D81_10020 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"E3D81_10945 rplT; 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"E3D81_06925 rplU; 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"E3D81_02735 50S ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"E3D81_02750 50S ribosomal protein L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"E3D81_02705 50S ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"E3D81_02015 50S ribosomal protein L25\/general stress protein Ctc\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"E3D81_06920 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"E3D81_16985 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"E3D81_02720 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"E3D81_02670 rpmD; 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"E3D81_04925 type B 50S ribosomal protein L31\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"E3D81_09165 rpmF; 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"E3D81_16980 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"E3D81_07700 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"E3D81_10940 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"E3D81_02645 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36"
				}
				]
			},
			{
				"name":"00970 Aminoacyl-tRNA biosynthesis [PATH:sphz00970]",
				"children":[
				{
					"name":"E3D81_00750 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_06915 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_11375 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_00280 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_05005 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_06205 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_06220 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_13620 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_07465 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"E3D81_07470 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"E3D81_01580 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_01585 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_01590 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_11785 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"E3D81_01965 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"E3D81_15095 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"E3D81_16855 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"E3D81_00940 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_03990 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_04790 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_09275 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_13790 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"E3D81_00745 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"E3D81_11370 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"E3D81_03995 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_04795 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_05880 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_07410 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_07910 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_00390 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_04305 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_12810 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_05020 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08640 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08645 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_09805 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_06745 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"E3D81_06770 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"E3D81_10025 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"E3D81_11630 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"E3D81_04170 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_04580 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_05715 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_13615 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_09265 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"E3D81_09280 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"E3D81_09290 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"E3D81_09270 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"E3D81_01370 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"E3D81_01375 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"E3D81_01465 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"E3D81_14785 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"E3D81_11575 alaS; alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"E3D81_07790 aspS; aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"E3D81_02985 asnS; asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"E3D81_02315 glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"E3D81_10930 thrS; threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"E3D81_10700 serS; serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"E3D81_08480 cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"E3D81_08275 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"E3D81_04885 methionyl-tRNA formyltransferase\tK00604 MTFMT; methionyl-tRNA formyltransferase [EC:2.1.2.9]"
				},
				{
					"name":"E3D81_07030 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"E3D81_03830 leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"E3D81_08970 isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"E3D81_04930 lysS; lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"E3D81_06340 arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"E3D81_11260 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"E3D81_02785 histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"E3D81_15270 pheS; phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_13090 phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_02075 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"E3D81_04730 trpS; tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"03013 Nucleocytoplasmic transport"
			},
			{
				"name":"03015 mRNA surveillance pathway"
			},
			{
				"name":"03008 Ribosome biogenesis in eukaryotes",
				"children":[
				{
					"name":"E3D81_02790 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			}
			]
		},
		{
			"name":"09123 Folding, sorting and degradation",
			"children":[
			{
				"name":"03060 Protein export [PATH:sphz03060]",
				"children":[
				{
					"name":"E3D81_02660 secY; preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"E3D81_09295 secE; preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"E3D81_15220 secG; preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"E3D81_06170 protein translocase subunit SecDF\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"E3D81_06880 yajC; preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"E3D81_10005 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"E3D81_17075 secA; preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"E3D81_09015 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"E3D81_08445 ffs; signal recognition particle sRNA small type\tK01983 ffs; signal recognition particle 4.5S RNA"
				},
				{
					"name":"E3D81_16970 ftsY; signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"E3D81_07835 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09890 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09140 tatC; twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
				},
				{
					"name":"E3D81_01415 lepB; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"E3D81_08960 lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"E3D81_03265 hypothetical protein\tK13280 SEC11; signal peptidase I [EC:3.4.21.89]"
				}
				]
			},
			{
				"name":"04141 Protein processing in endoplasmic reticulum [PATH:sphz04141]",
				"children":[
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"E3D81_07060 Hsp20\/alpha crystallin family protein\tK13993 HSP20; HSP20 family protein"
				}
				]
			},
			{
				"name":"04130 SNARE interactions in vesicular transport"
			},
			{
				"name":"04120 Ubiquitin mediated proteolysis"
			},
			{
				"name":"04122 Sulfur relay system [PATH:sphz04122]",
				"children":[
				{
					"name":"E3D81_10860 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_13725 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_07610 sulfurtransferase\tK01011 TST; thiosulfate\/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2]"
				},
				{
					"name":"E3D81_06740 mnmA; tRNA 2-thiouridine(34) synthase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"E3D81_05990 HesA\/MoeB\/ThiF family protein\tK21029 moeB; molybdopterin-synthase adenylyltransferase [EC:2.7.7.80]"
				},
				{
					"name":"E3D81_05960 thiS; sulfur carrier protein ThiS\tK03154 thiS; sulfur carrier protein"
				}
				]
			},
			{
				"name":"03050 Proteasome"
			},
			{
				"name":"03018 RNA degradation [PATH:sphz03018]",
				"children":[
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"E3D81_08155 pnp; polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"E3D81_08915 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"E3D81_11820 rnr; ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"E3D81_11530 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"E3D81_03580 recQ; DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_07655 RecQ family ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_07515 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"E3D81_13105 rny; ribonuclease Y\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"E3D81_03955 ppk1; polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				},
				{
					"name":"E3D81_08575 HD domain-containing protein\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"09124 Replication and repair",
			"children":[
			{
				"name":"03030 DNA replication [PATH:sphz03030]",
				"children":[
				{
					"name":"E3D81_03905 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_13070 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16105 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_04775 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11515 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17130 hypothetical protein\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11140 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17125 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_04505 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"E3D81_07315 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"E3D81_15905 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_06400 rnhA; ribonuclease HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"E3D81_16410 ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03410 Base excision repair [PATH:sphz03410]",
				"children":[
				{
					"name":"E3D81_02435 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"E3D81_00905 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"E3D81_15280 mutY; A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"E3D81_14845 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"E3D81_01505 xth; exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_08615 recJ; single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03420 Nucleotide excision repair [PATH:sphz03420]",
				"children":[
				{
					"name":"E3D81_15400 mfd; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_01010 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"E3D81_02900 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"E3D81_08795 uvrB; excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"E3D81_09460 excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"E3D81_07285 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_13605 ATP-dependent helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				}
				]
			},
			{
				"name":"03430 Mismatch repair [PATH:sphz03430]",
				"children":[
				{
					"name":"E3D81_08345 mutS; DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"E3D81_13310 endonuclease MutS2\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"E3D81_14525 mutL; DNA mismatch repair endonuclease MutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"E3D81_07285 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_13605 ATP-dependent helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_00995 xseA; exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"E3D81_01000 xseB; exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"E3D81_08615 recJ; single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_04775 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17125 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11515 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11140 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17130 hypothetical protein\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_03905 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_13070 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16105 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"E3D81_00110 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_05320 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				}
				]
			},
			{
				"name":"03440 Homologous recombination [PATH:sphz03440]",
				"children":[
				{
					"name":"E3D81_08615 recJ; single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_03015 recF; DNA replication and repair protein RecF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"E3D81_16995 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"E3D81_13330 recR; recombination protein RecR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"E3D81_02440 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_01785 ruvA; Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"E3D81_05515 ruvB; Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_02580 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"E3D81_01275 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_04775 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17125 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11515 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11140 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17130 hypothetical protein\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_03905 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_13070 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16105 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_01880 priA; primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"03450 Non-homologous end-joining [PATH:sphz03450]",
				"children":[
				{
					"name":"E3D81_12540 Ku protein\tK10979 ku; DNA end-binding protein Ku"
				},
				{
					"name":"E3D81_12535 ligD; DNA ligase D\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
				}
				]
			},
			{
				"name":"03460 Fanconi anemia pathway"
			}
			]
		},
		{
			"name":"09126 Chromosome",
			"children":[
			{
				"name":"03082 ATP-dependent chromatin remodeling"
			},
			{
				"name":"03083 Polycomb repressive complex"
			}
			]
		},
		{
			"name":"09125 Information processing in viruses",
			"children":[
			{
				"name":"03230 Viral genome structure"
			},
			{
				"name":"03240 Viral replication"
			},
			{
				"name":"03250 Viral life cycle - HIV-1"
			},
			{
				"name":"03260 Virion - Human immunodeficiency virus"
			},
			{
				"name":"03271 Virion - Rotavirus"
			},
			{
				"name":"03262 Virion - Coronavirus"
			},
			{
				"name":"03261 Virion - Influenza virus"
			},
			{
				"name":"03263 Virion - Enterovirus"
			},
			{
				"name":"03264 Virion - Flavivirus and Alphavirus"
			},
			{
				"name":"03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus"
			},
			{
				"name":"03273 Virion - Lassa virus and SFTS virus"
			},
			{
				"name":"03272 Virion - Hepatitis viruses",
				"children":[
				{
					"name":"E3D81_05385 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_11090 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				}
				]
			},
			{
				"name":"03266 Virion - Herpesvirus"
			},
			{
				"name":"03268 Virion - Orthopoxvirus"
			},
			{
				"name":"03267 Virion - Adenovirus"
			},
			{
				"name":"03259 Virion - Bacteriophages T4 and T7"
			},
			{
				"name":"03258 Virion - Bacteriophage lambda"
			}
			]
		}
		]
	},
	{
		"name":"09130 Environmental Information Processing",
		"children":[
		{
			"name":"09131 Membrane transport",
			"children":[
			{
				"name":"02010 ABC transporters [PATH:sphz02010]",
				"children":[
				{
					"name":"E3D81_02205 ATP-binding cassette domain-containing protein\tK05776 modF; molybdate transport system ATP-binding protein"
				},
				{
					"name":"E3D81_07875 MCE family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"E3D81_10730 MCE family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"E3D81_09635 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"E3D81_10720 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"E3D81_09640 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"E3D81_10725 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"E3D81_03660 PstS family phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_11930 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_03655 pstC; phosphate ABC transporter permease subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_11935 pstC; phosphate ABC transporter permease subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_03650 ABC transporter permease subunit\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_11940 pstA; phosphate ABC transporter permease PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_03645 phosphate ABC transporter ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"E3D81_11945 pstB; phosphate ABC transporter ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"E3D81_04880 ABC transporter permease\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"E3D81_16490 ABC transporter permease\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"E3D81_02355 ABC transporter ATP-binding protein\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"E3D81_01680 ABC transporter permease\tK02195 ccmC; heme exporter protein C"
				},
				{
					"name":"E3D81_01685 ABC transporter permease\tK02194 ccmB; heme exporter protein B"
				},
				{
					"name":"E3D81_09795 YjgP\/YjgQ family permease\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"E3D81_08465 YjgP\/YjgQ family permease\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"E3D81_08610 lptB; LPS export ABC transporter ATP-binding protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"E3D81_10580 ATP-binding cassette domain-containing protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"E3D81_16680 ABC transporter permease\tK19341 nosY; Cu-processing system permease protein"
				},
				{
					"name":"E3D81_16685 ABC transporter ATP-binding protein\tK19340 nosF; Cu-processing system ATP-binding protein"
				},
				{
					"name":"E3D81_03835 FtsX-like permease family protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"E3D81_03605 ATP-binding cassette domain-containing protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"E3D81_13165 ABC transporter ATP-binding protein\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]"
				},
				{
					"name":"E3D81_06900 ABC transporter ATP-binding protein\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"E3D81_00865 ABC transporter ATP-binding protein\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				}
				]
			},
			{
				"name":"02060 Phosphotransferase system (PTS)"
			},
			{
				"name":"03070 Bacterial secretion system [PATH:sphz03070]",
				"children":[
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_06170 protein translocase subunit SecDF\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"E3D81_09295 secE; preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"E3D81_15220 secG; preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"E3D81_02660 secY; preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"E3D81_06880 yajC; preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"E3D81_10005 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"E3D81_17075 secA; preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"E3D81_16970 ftsY; signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"E3D81_09015 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"E3D81_07835 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09890 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09140 tatC; twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
				}
				]
			}
			]
		},
		{
			"name":"09132 Signal transduction",
			"children":[
			{
				"name":"02020 Two-component system [PATH:sphz02020]",
				"children":[
				{
					"name":"E3D81_02820 GHKL domain-containing protein\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_10755 HAMP domain-containing histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_16455 sensor histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_10760 response regulator transcription factor\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"E3D81_11585 response regulator transcription factor\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"E3D81_03660 PstS family phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_11930 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_01485 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"E3D81_10245 TolC family protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"E3D81_10250 efflux RND transporter periplasmic adaptor subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"E3D81_10240 efflux RND transporter permease subunit\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"E3D81_08230 heme A synthase\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"E3D81_00005 dnaA; chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"E3D81_12325 lysylphosphatidylglycerol synthetase family protein\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				},
				{
					"name":"E3D81_07295 peptidase M15\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
				},
				{
					"name":"E3D81_07710 response regulator transcription factor\tK07689 uvrY; two-component system, NarL family, invasion response regulator UvrY"
				},
				{
					"name":"E3D81_12530 response regulator transcription factor\tK07696 nreC; two-component system, NarL family, response regulator NreC"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_09245 sigma-54-dependent Fis family transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_13460 dctA; C4-dicarboxylate transporter DctA\tK11103 dctA; aerobic C4-dicarboxylate transport protein"
				},
				{
					"name":"E3D81_12360 rpoN; RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"E3D81_02850 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"E3D81_15530 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"E3D81_02855 chemotaxis protein CheB\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"E3D81_04685 GHKL domain-containing protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_16715 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"E3D81_11410 ccoN; cytochrome-c oxidase, cbb3-type subunit I\tK15862 ccoNO; cytochrome c oxidase cbb3-type subunit I\/II [EC:7.1.1.9]"
				},
				{
					"name":"E3D81_11420 c-type cytochrome\tK00406 ccoP; cytochrome c oxidase cbb3-type subunit III"
				},
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_03290 sugar transporter\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"E3D81_15940 sugar transporter\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"E3D81_01490 low molecular weight phosphotyrosine protein phosphatase\tK25307 wzb; low molecular weight protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"E3D81_03295 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_04420 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15885 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15935 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_02120 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_05150 sigma-70 family RNA polymerase sigma factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_08825 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_13210 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_16355 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_02125 FecR family protein\tK07165 fecR; transmembrane sensor"
				},
				{
					"name":"E3D81_16740 DUF4974 domain-containing protein\tK07165 fecR; transmembrane sensor"
				}
				]
			},
			{
				"name":"04010 MAPK signaling pathway"
			},
			{
				"name":"04013 MAPK signaling pathway - fly"
			},
			{
				"name":"04016 MAPK signaling pathway - plant"
			},
			{
				"name":"04011 MAPK signaling pathway - yeast"
			},
			{
				"name":"04012 ErbB signaling pathway"
			},
			{
				"name":"04014 Ras signaling pathway"
			},
			{
				"name":"04015 Rap1 signaling pathway"
			},
			{
				"name":"04310 Wnt signaling pathway"
			},
			{
				"name":"04330 Notch signaling pathway"
			},
			{
				"name":"04340 Hedgehog signaling pathway"
			},
			{
				"name":"04341 Hedgehog signaling pathway - fly"
			},
			{
				"name":"04350 TGF-beta signaling pathway"
			},
			{
				"name":"04390 Hippo signaling pathway"
			},
			{
				"name":"04391 Hippo signaling pathway - fly"
			},
			{
				"name":"04392 Hippo signaling pathway - multiple species"
			},
			{
				"name":"04370 VEGF signaling pathway"
			},
			{
				"name":"04371 Apelin signaling pathway"
			},
			{
				"name":"04630 JAK-STAT signaling pathway"
			},
			{
				"name":"04064 NF-kappa B signaling pathway"
			},
			{
				"name":"04668 TNF signaling pathway"
			},
			{
				"name":"04066 HIF-1 signaling pathway"
			},
			{
				"name":"04068 FoxO signaling pathway"
			},
			{
				"name":"04020 Calcium signaling pathway"
			},
			{
				"name":"04070 Phosphatidylinositol signaling system"
			},
			{
				"name":"04072 Phospholipase D signaling pathway"
			},
			{
				"name":"04071 Sphingolipid signaling pathway"
			},
			{
				"name":"04024 cAMP signaling pathway"
			},
			{
				"name":"04022 cGMP-PKG signaling pathway"
			},
			{
				"name":"04151 PI3K-Akt signaling pathway"
			},
			{
				"name":"04152 AMPK signaling pathway"
			},
			{
				"name":"04150 mTOR signaling pathway"
			},
			{
				"name":"04075 Plant hormone signal transduction"
			}
			]
		},
		{
			"name":"09133 Signaling molecules and interaction",
			"children":[
			{
				"name":"04080 Neuroactive ligand-receptor interaction"
			},
			{
				"name":"04082 Neuroactive ligand signaling"
			},
			{
				"name":"04081 Hormone signaling"
			},
			{
				"name":"04060 Cytokine-cytokine receptor interaction"
			},
			{
				"name":"04061 Viral protein interaction with cytokine and cytokine receptor"
			},
			{
				"name":"04512 ECM-receptor interaction"
			},
			{
				"name":"04514 Cell adhesion molecule (CAM) interaction"
			},
			{
				"name":"04517 IgSF CAM signaling"
			},
			{
				"name":"04518 Integrin signaling"
			},
			{
				"name":"04519 Cadherin signaling"
			}
			]
		}
		]
	},
	{
		"name":"09140 Cellular Processes",
		"children":[
		{
			"name":"09141 Transport and catabolism",
			"children":[
			{
				"name":"04144 Endocytosis"
			},
			{
				"name":"04145 Phagocytosis",
				"children":[
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				}
				]
			},
			{
				"name":"04142 Lysosome biogenesis [PATH:sphz04142]",
				"children":[
				{
					"name":"E3D81_08715 formylglycine-generating enzyme family protein\tK13444 SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]"
				},
				{
					"name":"E3D81_15175 gliding motility-associated lipoprotein\tK13444 SUMF1; formylglycine-generating enzyme [EC:1.8.3.7]"
				},
				{
					"name":"E3D81_08325 glucosylceramidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"E3D81_02290 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_06670 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_08115 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_12035 alpha-1,3\/4-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_08735 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_15090 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_00305 sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00315 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_00320 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_09360 exo-alpha-sialidase\tK01186 NEU1; sialidase-1 [EC:3.2.1.18]"
				},
				{
					"name":"E3D81_15590 iduronate-2-sulfatase\tK01136 IDS; iduronate 2-sulfatase [EC:3.1.6.13]"
				},
				{
					"name":"E3D81_10605 glycosylasparaginase\tK01444 AGA; N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26]"
				}
				]
			},
			{
				"name":"04146 Peroxisome [PATH:sphz04146]",
				"children":[
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_04215 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_04870 NADP-dependent isocitrate dehydrogenase\tK00031 IDH1; isocitrate dehydrogenase [EC:1.1.1.42]"
				},
				{
					"name":"E3D81_00025 hydroxymethylglutaryl-CoA lyase\tK01640 HMGCL; hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4]"
				},
				{
					"name":"E3D81_13975 catalase\tK03781 katE; catalase [EC:1.11.1.6]"
				},
				{
					"name":"E3D81_02465 superoxide dismutase\tK04564 SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]"
				}
				]
			},
			{
				"name":"04149 Peroxisome - yeast"
			},
			{
				"name":"04140 Autophagy - animal"
			},
			{
				"name":"04138 Autophagy - yeast"
			},
			{
				"name":"04136 Autophagy - other"
			},
			{
				"name":"04137 Mitophagy - animal"
			},
			{
				"name":"04139 Mitophagy - yeast"
			},
			{
				"name":"04148 Efferocytosis"
			}
			]
		},
		{
			"name":"09143 Cell growth and death",
			"children":[
			{
				"name":"04110 Cell cycle"
			},
			{
				"name":"04111 Cell cycle - yeast"
			},
			{
				"name":"04112 Cell cycle - Caulobacter"
			},
			{
				"name":"04113 Meiosis - yeast"
			},
			{
				"name":"04114 Oocyte meiosis"
			},
			{
				"name":"04210 Apoptosis"
			},
			{
				"name":"04214 Apoptosis - fly"
			},
			{
				"name":"04215 Apoptosis - multiple species"
			},
			{
				"name":"04216 Ferroptosis"
			},
			{
				"name":"04217 Necroptosis"
			},
			{
				"name":"04115 p53 signaling pathway"
			},
			{
				"name":"04218 Cellular senescence"
			},
			{
				"name":"04156 Integrated stress response (ISR) signaling pathway [PATH:sphz04156]",
				"children":[
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"E3D81_05020 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08640 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08645 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_09805 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				}
				]
			}
			]
		},
		{
			"name":"09144 Cellular community - eukaryotes",
			"children":[
			{
				"name":"04510 Focal adhesion"
			},
			{
				"name":"04520 Adherens junction"
			},
			{
				"name":"04530 Tight junction"
			},
			{
				"name":"04540 Gap junction"
			},
			{
				"name":"04550 Signaling pathways regulating pluripotency of stem cells"
			}
			]
		},
		{
			"name":"09145 Cellular community - prokaryotes",
			"children":[
			{
				"name":"02024 Quorum sensing [PATH:sphz02024]",
				"children":[
				{
					"name":"E3D81_14910 anthranilate synthase component I family protein\tK01657 trpE; anthranilate synthase component I [EC:4.1.3.27]"
				},
				{
					"name":"E3D81_14915 aminodeoxychorismate\/anthranilate synthase component II\tK01658 trpG; anthranilate synthase component II [EC:4.1.3.27]"
				},
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_16715 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"E3D81_12820 ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase\/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD\tK11752 ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase \/ 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]"
				},
				{
					"name":"E3D81_05070 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12245 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_10005 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"E3D81_06170 protein translocase subunit SecDF\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"E3D81_09295 secE; preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"E3D81_15220 secG; preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"E3D81_02660 secY; preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"E3D81_06880 yajC; preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"E3D81_17075 secA; preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"E3D81_16970 ftsY; signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"E3D81_09015 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"E3D81_13565 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				}
				]
			},
			{
				"name":"05111 Biofilm formation - Vibrio cholerae"
			},
			{
				"name":"02025 Biofilm formation - Pseudomonas aeruginosa"
			},
			{
				"name":"02026 Biofilm formation - Escherichia coli"
			}
			]
		},
		{
			"name":"09142 Cell motility",
			"children":[
			{
				"name":"02030 Bacterial chemotaxis [PATH:sphz02030]",
				"children":[
				{
					"name":"E3D81_02855 chemotaxis protein CheB\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"E3D81_02850 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"E3D81_15530 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				}
				]
			},
			{
				"name":"02040 Flagellar assembly [PATH:sphz02040]",
				"children":[
				{
					"name":"E3D81_04895 RNA polymerase sigma factor RpoD\/SigA\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"E3D81_12360 rpoN; RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor"
				}
				]
			},
			{
				"name":"04814 Motor proteins"
			},
			{
				"name":"04820 Cytoskeleton in muscle cells",
				"children":[
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				}
				]
			},
			{
				"name":"04810 Regulation of actin cytoskeleton"
			}
			]
		}
		]
	},
	{
		"name":"09150 Organismal Systems",
		"children":[
		{
			"name":"09151 Immune system",
			"children":[
			{
				"name":"04640 Hematopoietic cell lineage"
			},
			{
				"name":"04610 Complement and coagulation cascades"
			},
			{
				"name":"04611 Platelet activation"
			},
			{
				"name":"04613 Neutrophil extracellular trap formation"
			},
			{
				"name":"04620 Toll-like receptor signaling pathway"
			},
			{
				"name":"04624 Toll and Imd signaling pathway"
			},
			{
				"name":"04621 NOD-like receptor signaling pathway"
			},
			{
				"name":"04622 RIG-I-like receptor signaling pathway"
			},
			{
				"name":"04623 Cytosolic DNA-sensing pathway"
			},
			{
				"name":"04625 C-type lectin receptor signaling pathway"
			},
			{
				"name":"04650 Natural killer cell mediated cytotoxicity"
			},
			{
				"name":"04612 Antigen processing and presentation"
			},
			{
				"name":"04660 T cell receptor signaling pathway"
			},
			{
				"name":"04658 Th1 and Th2 cell differentiation"
			},
			{
				"name":"04659 Th17 cell differentiation"
			},
			{
				"name":"04657 IL-17 signaling pathway"
			},
			{
				"name":"04662 B cell receptor signaling pathway"
			},
			{
				"name":"04664 Fc epsilon RI signaling pathway"
			},
			{
				"name":"04666 Fc gamma R-mediated phagosome formation"
			},
			{
				"name":"04670 Leukocyte transendothelial migration"
			},
			{
				"name":"04672 Intestinal immune network for IgA production"
			},
			{
				"name":"04062 Chemokine signaling pathway"
			}
			]
		},
		{
			"name":"09152 Endocrine system",
			"children":[
			{
				"name":"04911 Insulin secretion"
			},
			{
				"name":"04910 Insulin signaling pathway"
			},
			{
				"name":"04922 Glucagon signaling pathway"
			},
			{
				"name":"04923 Regulation of lipolysis in adipocytes"
			},
			{
				"name":"04920 Adipocytokine signaling pathway"
			},
			{
				"name":"03320 PPAR signaling pathway"
			},
			{
				"name":"04929 GnRH secretion"
			},
			{
				"name":"04912 GnRH signaling pathway"
			},
			{
				"name":"04913 Ovarian steroidogenesis"
			},
			{
				"name":"04915 Estrogen signaling pathway"
			},
			{
				"name":"04914 Progesterone-mediated oocyte maturation"
			},
			{
				"name":"04917 Prolactin signaling pathway"
			},
			{
				"name":"04921 Oxytocin signaling pathway"
			},
			{
				"name":"04926 Relaxin signaling pathway"
			},
			{
				"name":"04935 Growth hormone synthesis, secretion and action"
			},
			{
				"name":"04918 Thyroid hormone synthesis"
			},
			{
				"name":"04919 Thyroid hormone signaling pathway"
			},
			{
				"name":"04928 Parathyroid hormone synthesis, secretion and action"
			},
			{
				"name":"04916 Melanogenesis"
			},
			{
				"name":"04924 Renin secretion"
			},
			{
				"name":"04614 Renin-angiotensin system"
			},
			{
				"name":"04925 Aldosterone synthesis and secretion"
			},
			{
				"name":"04927 Cortisol synthesis and secretion"
			}
			]
		},
		{
			"name":"09153 Circulatory system",
			"children":[
			{
				"name":"04260 Cardiac muscle contraction"
			},
			{
				"name":"04261 Adrenergic signaling in cardiomyocytes"
			},
			{
				"name":"04270 Vascular smooth muscle contraction"
			}
			]
		},
		{
			"name":"09154 Digestive system",
			"children":[
			{
				"name":"04970 Salivary secretion"
			},
			{
				"name":"04971 Gastric acid secretion"
			},
			{
				"name":"04972 Pancreatic secretion"
			},
			{
				"name":"04976 Bile secretion"
			},
			{
				"name":"04973 Carbohydrate digestion and absorption"
			},
			{
				"name":"04974 Protein digestion and absorption"
			},
			{
				"name":"04975 Fat digestion and absorption"
			},
			{
				"name":"04979 Cholesterol metabolism"
			},
			{
				"name":"04977 Vitamin digestion and absorption"
			},
			{
				"name":"04981 Folate transport and metabolism [PATH:sphz04981]",
				"children":[
				{
					"name":"E3D81_14995 5-formyltetrahydrofolate cyclo-ligase\tK01934 MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]"
				},
				{
					"name":"E3D81_11470 dihydrofolate reductase\tK00287 DHFR; dihydrofolate reductase [EC:1.5.1.3]"
				},
				{
					"name":"E3D81_08980 serine hydroxymethyltransferase\tK00600 glyA; glycine hydroxymethyltransferase [EC:2.1.2.1]"
				},
				{
					"name":"E3D81_11475 thymidylate synthase\tK00560 thyA; thymidylate synthase [EC:2.1.1.45]"
				}
				]
			},
			{
				"name":"04980 Cobalamin transport and metabolism"
			},
			{
				"name":"04978 Mineral absorption"
			}
			]
		},
		{
			"name":"09155 Excretory system",
			"children":[
			{
				"name":"04962 Vasopressin-regulated water reabsorption"
			},
			{
				"name":"04960 Aldosterone-regulated sodium reabsorption"
			},
			{
				"name":"04961 Endocrine and other factor-regulated calcium reabsorption"
			},
			{
				"name":"04964 Proximal tubule bicarbonate reclamation"
			},
			{
				"name":"04966 Collecting duct acid secretion"
			}
			]
		},
		{
			"name":"09156 Nervous system",
			"children":[
			{
				"name":"04724 Glutamatergic synapse"
			},
			{
				"name":"04727 GABAergic synapse"
			},
			{
				"name":"04725 Cholinergic synapse"
			},
			{
				"name":"04728 Dopaminergic synapse"
			},
			{
				"name":"04726 Serotonergic synapse"
			},
			{
				"name":"04720 Long-term potentiation"
			},
			{
				"name":"04730 Long-term depression"
			},
			{
				"name":"04723 Retrograde endocannabinoid signaling"
			},
			{
				"name":"04721 Synaptic vesicle cycle"
			},
			{
				"name":"04722 Neurotrophin signaling pathway"
			}
			]
		},
		{
			"name":"09157 Sensory system",
			"children":[
			{
				"name":"04744 Phototransduction"
			},
			{
				"name":"04745 Phototransduction - fly"
			},
			{
				"name":"04740 Olfactory transduction"
			},
			{
				"name":"04742 Taste transduction"
			},
			{
				"name":"04750 Inflammatory mediator regulation of TRP channels"
			}
			]
		},
		{
			"name":"09158 Development and regeneration",
			"children":[
			{
				"name":"04320 Dorso-ventral axis formation"
			},
			{
				"name":"04360 Axon guidance"
			},
			{
				"name":"04361 Axon regeneration"
			},
			{
				"name":"04380 Osteoclast differentiation"
			},
			{
				"name":"04382 Cornified envelope formation [PATH:sphz04382]",
				"children":[
				{
					"name":"E3D81_01830 pyridoxal phosphate-dependent aminotransferase family protein\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"E3D81_08325 glucosylceramidase\tK01201 GBA; glucosylceramidase [EC:3.2.1.45]"
				},
				{
					"name":"E3D81_01625 aminopeptidase\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"E3D81_07635 hutH; histidine ammonia-lyase\tK01745 hutH; histidine ammonia-lyase [EC:4.3.1.3]"
				}
				]
			}
			]
		},
		{
			"name":"09149 Aging",
			"children":[
			{
				"name":"04211 Longevity regulating pathway"
			},
			{
				"name":"04212 Longevity regulating pathway - worm"
			},
			{
				"name":"04213 Longevity regulating pathway - multiple species"
			}
			]
		},
		{
			"name":"09159 Environmental adaptation",
			"children":[
			{
				"name":"04710 Circadian rhythm"
			},
			{
				"name":"04713 Circadian entrainment"
			},
			{
				"name":"04711 Circadian rhythm - fly"
			},
			{
				"name":"04712 Circadian rhythm - plant"
			},
			{
				"name":"04714 Thermogenesis"
			},
			{
				"name":"04626 Plant-pathogen interaction"
			}
			]
		}
		]
	},
	{
		"name":"09160 Human Diseases",
		"children":[
		{
			"name":"09161 Cancer: overview",
			"children":[
			{
				"name":"05200 Pathways in cancer"
			},
			{
				"name":"05202 Transcriptional misregulation in cancer"
			},
			{
				"name":"05206 MicroRNAs in cancer"
			},
			{
				"name":"05205 Proteoglycans in cancer"
			},
			{
				"name":"05204 Chemical carcinogenesis - DNA adducts"
			},
			{
				"name":"05207 Chemical carcinogenesis - receptor activation"
			},
			{
				"name":"05208 Chemical carcinogenesis - reactive oxygen species"
			},
			{
				"name":"05203 Viral carcinogenesis"
			},
			{
				"name":"05230 Central carbon metabolism in cancer"
			},
			{
				"name":"05231 Choline metabolism in cancer"
			},
			{
				"name":"05235 PD-L1 expression and PD-1 checkpoint pathway in cancer"
			}
			]
		},
		{
			"name":"09162 Cancer: specific types",
			"children":[
			{
				"name":"05210 Colorectal cancer"
			},
			{
				"name":"05212 Pancreatic cancer"
			},
			{
				"name":"05225 Hepatocellular carcinoma"
			},
			{
				"name":"05226 Gastric cancer"
			},
			{
				"name":"05214 Glioma"
			},
			{
				"name":"05216 Thyroid cancer"
			},
			{
				"name":"05221 Acute myeloid leukemia"
			},
			{
				"name":"05220 Chronic myeloid leukemia"
			},
			{
				"name":"05217 Basal cell carcinoma"
			},
			{
				"name":"05218 Melanoma"
			},
			{
				"name":"05211 Renal cell carcinoma"
			},
			{
				"name":"05219 Bladder cancer"
			},
			{
				"name":"05215 Prostate cancer"
			},
			{
				"name":"05213 Endometrial cancer"
			},
			{
				"name":"05224 Breast cancer"
			},
			{
				"name":"05222 Small cell lung cancer"
			},
			{
				"name":"05223 Non-small cell lung cancer"
			}
			]
		},
		{
			"name":"09172 Infectious disease: viral",
			"children":[
			{
				"name":"05166 Human T-cell leukemia virus 1 infection"
			},
			{
				"name":"05170 Human immunodeficiency virus 1 infection"
			},
			{
				"name":"05161 Hepatitis B"
			},
			{
				"name":"05160 Hepatitis C"
			},
			{
				"name":"05171 Coronavirus disease"
			},
			{
				"name":"05164 Influenza A"
			},
			{
				"name":"05162 Measles"
			},
			{
				"name":"05168 Herpes simplex virus 1 infection"
			},
			{
				"name":"05163 Human cytomegalovirus infection"
			},
			{
				"name":"05167 Kaposi sarcoma-associated herpesvirus infection"
			},
			{
				"name":"05169 Epstein-Barr virus infection"
			},
			{
				"name":"05165 Human papillomavirus infection"
			}
			]
		},
		{
			"name":"09171 Infectious disease: bacterial",
			"children":[
			{
				"name":"05110 Vibrio cholerae infection"
			},
			{
				"name":"05120 Epithelial cell signaling in Helicobacter pylori infection"
			},
			{
				"name":"05130 Pathogenic Escherichia coli infection"
			},
			{
				"name":"05132 Salmonella infection"
			},
			{
				"name":"05131 Shigellosis"
			},
			{
				"name":"05135 Yersinia infection"
			},
			{
				"name":"05133 Pertussis"
			},
			{
				"name":"05134 Legionellosis"
			},
			{
				"name":"05150 Staphylococcus aureus infection"
			},
			{
				"name":"05152 Tuberculosis"
			},
			{
				"name":"05100 Bacterial invasion of epithelial cells"
			}
			]
		},
		{
			"name":"09174 Infectious disease: parasitic",
			"children":[
			{
				"name":"05146 Amoebiasis"
			},
			{
				"name":"05144 Malaria"
			},
			{
				"name":"05145 Toxoplasmosis"
			},
			{
				"name":"05140 Leishmaniasis"
			},
			{
				"name":"05142 Chagas disease"
			},
			{
				"name":"05143 African trypanosomiasis"
			}
			]
		},
		{
			"name":"09163 Immune disease",
			"children":[
			{
				"name":"05310 Asthma"
			},
			{
				"name":"05322 Systemic lupus erythematosus"
			},
			{
				"name":"05323 Rheumatoid arthritis"
			},
			{
				"name":"05320 Autoimmune thyroid disease"
			},
			{
				"name":"05321 Inflammatory bowel disease"
			},
			{
				"name":"05330 Allograft rejection"
			},
			{
				"name":"05332 Graft-versus-host disease"
			},
			{
				"name":"05340 Primary immunodeficiency"
			}
			]
		},
		{
			"name":"09164 Neurodegenerative disease",
			"children":[
			{
				"name":"05010 Alzheimer disease"
			},
			{
				"name":"05012 Parkinson disease"
			},
			{
				"name":"05014 Amyotrophic lateral sclerosis"
			},
			{
				"name":"05016 Huntington disease"
			},
			{
				"name":"05017 Spinocerebellar ataxia"
			},
			{
				"name":"05020 Prion disease"
			},
			{
				"name":"05022 Pathways of neurodegeneration - multiple diseases"
			}
			]
		},
		{
			"name":"09165 Substance dependence",
			"children":[
			{
				"name":"05030 Cocaine addiction"
			},
			{
				"name":"05031 Amphetamine addiction"
			},
			{
				"name":"05032 Morphine addiction"
			},
			{
				"name":"05033 Nicotine addiction"
			},
			{
				"name":"05034 Alcoholism"
			}
			]
		},
		{
			"name":"09166 Cardiovascular disease",
			"children":[
			{
				"name":"05417 Lipid and atherosclerosis"
			},
			{
				"name":"05418 Fluid shear stress and atherosclerosis"
			},
			{
				"name":"05410 Hypertrophic cardiomyopathy"
			},
			{
				"name":"05412 Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"05414 Dilated cardiomyopathy"
			},
			{
				"name":"05415 Diabetic cardiomyopathy"
			},
			{
				"name":"05416 Viral myocarditis"
			}
			]
		},
		{
			"name":"09167 Endocrine and metabolic disease",
			"children":[
			{
				"name":"04930 Type II diabetes mellitus"
			},
			{
				"name":"04940 Type I diabetes mellitus"
			},
			{
				"name":"04950 Maturity onset diabetes of the young"
			},
			{
				"name":"04936 Alcoholic liver disease"
			},
			{
				"name":"04932 Non-alcoholic fatty liver disease"
			},
			{
				"name":"04931 Insulin resistance"
			},
			{
				"name":"04933 AGE-RAGE signaling pathway in diabetic complications"
			},
			{
				"name":"04934 Cushing syndrome"
			}
			]
		},
		{
			"name":"09175 Drug resistance: antimicrobial",
			"children":[
			{
				"name":"01501 beta-Lactam resistance [PATH:sphz01501]",
				"children":[
				{
					"name":"E3D81_01225 glycoside hydrolase family 3\tK01207 nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_00730 hypothetical protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_02040 M56 family peptidase\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_09070 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_00735 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_02045 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03715 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03730 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_09065 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_14365 bla; class A beta-lactamase\tK17836 penP; beta-lactamase class A [EC:3.5.2.6]"
				},
				{
					"name":"E3D81_11190 TetR\/AcrR family transcriptional regulator\tK18136 acrR; TetR\/AcrR family transcriptional regulator, multidrug resistance operon repressor"
				},
				{
					"name":"E3D81_05060 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06705 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_08695 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11180 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11350 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11920 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12235 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_05065 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_06700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_07040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_08700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11175 multidrug efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11355 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11915 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_12240 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_05070 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12245 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09455 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_12365 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_07200 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_07770 PASTA domain-containing protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				}
				]
			},
			{
				"name":"01502 Vancomycin resistance [PATH:sphz01502]",
				"children":[
				{
					"name":"E3D81_07295 peptidase M15\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
				},
				{
					"name":"E3D81_07575 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"E3D81_03980 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase\/alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"E3D81_01025 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase\tK01929 murF; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]"
				},
				{
					"name":"E3D81_07760 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"E3D81_07745 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				}
				]
			},
			{
				"name":"01503 Cationic antimicrobial peptide (CAMP) resistance [PATH:sphz01503]",
				"children":[
				{
					"name":"E3D81_10855 copper resistance protein NlpE\tK06079 cutF; copper homeostasis protein (lipoprotein)"
				},
				{
					"name":"E3D81_07865 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_07870 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_01485 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"E3D81_05060 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06705 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_08695 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11180 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11350 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11920 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12235 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_05065 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_06700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_07040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_08700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11175 multidrug efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11355 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11915 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_12240 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_15010 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"E3D81_12325 lysylphosphatidylglycerol synthetase family protein\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				}
				]
			}
			]
		},
		{
			"name":"09176 Drug resistance: antineoplastic",
			"children":[
			{
				"name":"01521 EGFR tyrosine kinase inhibitor resistance"
			},
			{
				"name":"01524 Platinum drug resistance"
			},
			{
				"name":"01523 Antifolate resistance"
			},
			{
				"name":"01522 Endocrine resistance"
			}
			]
		}
		]
	},
	{
		"name":"09180 Brite Hierarchies",
		"children":[
		{
			"name":"09181 Protein families: metabolism",
			"children":[
			{
				"name":"01000 Enzymes [BR:sphz01000]"
			},
			{
				"name":"01001 Protein kinases [BR:sphz01001]",
				"children":[
				{
					"name":"E3D81_12155 type II toxin-antitoxin system HipA family toxin\tK07154 hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
				},
				{
					"name":"E3D81_03295 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_04420 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15885 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15935 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_02820 GHKL domain-containing protein\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_10755 HAMP domain-containing histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_16455 sensor histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_15830 histidine kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_04685 GHKL domain-containing protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"01009 Protein phosphatases and associated proteins [BR:sphz01009]",
				"children":[
				{
					"name":"E3D81_08765 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"01002 Peptidases and inhibitors [BR:sphz01002]",
				"children":[
				{
					"name":"E3D81_08960 lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
				},
				{
					"name":"E3D81_01625 aminopeptidase\tK01372 BLMH; bleomycin hydrolase [EC:3.4.22.40]"
				},
				{
					"name":"E3D81_05835 guaA; glutamine-hydrolyzing GMP synthase\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
				},
				{
					"name":"E3D81_09905 glycoside hydrolase\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
				},
				{
					"name":"E3D81_10610 hydrolase\tK20742 ykfC; gamma-D-glutamyl-L-lysine dipeptidyl-peptidase [EC:3.4.14.13]"
				},
				{
					"name":"E3D81_06540 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
				},
				{
					"name":"E3D81_03055 gltB; glutamate synthase large subunit\tK00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]"
				},
				{
					"name":"E3D81_11590 glmS; glutamine--fructose-6-phosphate transaminase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
				},
				{
					"name":"E3D81_06985 asparagine synthase B\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
				},
				{
					"name":"E3D81_03945 DJ-1\/PfpI family protein\tK05520 yhbO; deglycase [EC:3.5.1.124]"
				},
				{
					"name":"E3D81_03400 hypothetical protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
				},
				{
					"name":"E3D81_00150 CPBP family intramembrane metalloprotease\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"E3D81_08040 CPBP family intramembrane metalloprotease\tK07052 K07052; CAAX protease family protein"
				},
				{
					"name":"E3D81_00860 M3 family peptidase\tK01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]"
				},
				{
					"name":"E3D81_06375 M3 family peptidase\tK01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]"
				},
				{
					"name":"E3D81_06560 M13 family peptidase\tK07386 pepO; putative endopeptidase [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_07295 peptidase M15\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
				},
				{
					"name":"E3D81_04935 insulinase family protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_13680 insulinase family protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_13685 insulinase family protein\tK07263 pqqL; zinc protease [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_00985 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"E3D81_14635 pepT; peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
				},
				{
					"name":"E3D81_02655 map; type I methionyl aminopeptidase\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
				},
				{
					"name":"E3D81_01800 aminopeptidase P family protein\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
				},
				{
					"name":"E3D81_01055 hflB; ATP-dependent zinc metalloprotease FtsH\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_11110 rseP; RIP metalloprotease RseP\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_00730 hypothetical protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_02040 M56 family peptidase\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_09070 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_15205 peptidase\tK09933 mtfA; MtfA peptidase"
				},
				{
					"name":"E3D81_01485 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"E3D81_02430 peptidase S8\tK13274 wprA; cell wall-associated protease [EC:3.4.21.-]"
				},
				{
					"name":"E3D81_01615 S9 family peptidase\tK01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]"
				},
				{
					"name":"E3D81_05385 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_11090 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_02425 S9 family peptidase\tK01354 ptrB; oligopeptidase B [EC:3.4.21.83]"
				},
				{
					"name":"E3D81_01795 dacB; D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"E3D81_05555 peptidase S13\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"E3D81_11150 clpP; ATP-dependent Clp endopeptidase proteolytic subunit ClpP\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
				},
				{
					"name":"E3D81_06390 lon; endopeptidase La\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]"
				},
				{
					"name":"E3D81_01415 lepB; signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"E3D81_03265 hypothetical protein\tK13280 SEC11; signal peptidase I [EC:3.4.21.89]"
				},
				{
					"name":"E3D81_02375 hypothetical protein\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"E3D81_14545 S41 family peptidase\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"E3D81_16155 tail-specific protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
				},
				{
					"name":"E3D81_00140 peptidase S41\tK08676 tri; tricorn protease [EC:3.4.21.-]"
				},
				{
					"name":"E3D81_07495 sppA; signal peptide peptidase SppA\tK04773 sppA; protease IV [EC:3.4.21.-]"
				},
				{
					"name":"E3D81_14530 rhomboid family intramembrane serine protease\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
				},
				{
					"name":"E3D81_10590 LD-carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"E3D81_08335 isoaspartyl peptidase\/L-asparaginase\tK13051 ASRGL1; L-asparaginase \/ beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]"
				},
				{
					"name":"E3D81_14970 ggt; gamma-glutamyltransferase\tK00681 ggt; gamma-glutamyltranspeptidase \/ glutathione hydrolase [EC:2.3.2.2 3.4.19.13]"
				},
				{
					"name":"E3D81_00840 proteinase inhibitor\tK08276 eco; ecotin"
				}
				]
			},
			{
				"name":"01003 Glycosyltransferases [BR:sphz01003]",
				"children":[
				{
					"name":"E3D81_05520 polyprenol monophosphomannose synthase\tK00721 DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]"
				},
				{
					"name":"E3D81_11995 glycosyltransferase\tK19002 mgs; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]"
				},
				{
					"name":"E3D81_09440 starch synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"E3D81_12900 glycogen synthase\tK00703 glgA; starch synthase [EC:2.4.1.21]"
				},
				{
					"name":"E3D81_08340 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_09455 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_12365 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_07750 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_07205 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				}
				]
			},
			{
				"name":"01005 Lipopolysaccharide biosynthesis proteins [BR:sphz01005]",
				"children":[
				{
					"name":"E3D81_15010 lpxA; acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase\tK00677 lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]"
				},
				{
					"name":"E3D81_03930 lipid-A-disaccharide synthase\tK00748 lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]"
				},
				{
					"name":"E3D81_15015 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\/3-hydroxyacyl-ACP dehydratase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"E3D81_15020 lpxD; UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase\tK02536 lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]"
				},
				{
					"name":"E3D81_01610 UDP-2,3-diacylglucosamine diphosphatase\tK03269 lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]"
				},
				{
					"name":"E3D81_17150 lpxK; tetraacyldisaccharide 4'-kinase\tK00912 lpxK; tetraacyldisaccharide 4'-kinase [EC:2.7.1.130]"
				},
				{
					"name":"E3D81_06260 lauroyl acyltransferase\tK02517 lpxL; Kdo2-lipid IVA lauroyltransferase\/acyltransferase [EC:2.3.1.241 2.3.1.-]"
				},
				{
					"name":"E3D81_15370 3-deoxy-D-manno-octulosonic acid transferase\tK02527 kdtA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]"
				},
				{
					"name":"E3D81_03585 3-deoxy-8-phosphooctulonate synthase\tK01627 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]"
				},
				{
					"name":"E3D81_04740 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase\tK00979 kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]"
				},
				{
					"name":"E3D81_02835 HAD-IIIA family hydrolase\tK03270 kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]"
				},
				{
					"name":"E3D81_03575 KpsF\/GutQ family sugar-phosphate isomerase\tK06041 kdsD; arabinose-5-phosphate isomerase [EC:5.3.1.13]"
				},
				{
					"name":"E3D81_03155 undecaprenyl\/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase\tK02851 wecA; UDP-GlcNAc:undecaprenyl-phosphate\/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]"
				},
				{
					"name":"E3D81_03160 NAD-dependent epimerase\/dehydratase family protein\tK19997 gnu; GlcNAc-P-P-Und epimerase [EC:5.1.3.26]"
				}
				]
			},
			{
				"name":"01011 Peptidoglycan biosynthesis and degradation proteins [BR:sphz01011]",
				"children":[
				{
					"name":"E3D81_07275 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
				},
				{
					"name":"E3D81_07450 murB; UDP-N-acetylmuramate dehydrogenase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
				},
				{
					"name":"E3D81_07740 UDP-N-acetylmuramate--L-alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
				},
				{
					"name":"E3D81_07755 murD; UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
				},
				{
					"name":"E3D81_07765 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
				},
				{
					"name":"E3D81_03980 bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase\/alanine racemase\tK01798 alr-murF; Alr-MurF fusion protein [EC:5.1.1.1 6.3.2.10]"
				},
				{
					"name":"E3D81_07575 D-alanine--D-alanine ligase\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
				},
				{
					"name":"E3D81_07120 murI; glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
				},
				{
					"name":"E3D81_10590 LD-carboxypeptidase\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
				},
				{
					"name":"E3D81_07760 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
				},
				{
					"name":"E3D81_07745 murG; undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
				},
				{
					"name":"E3D81_03845 undecaprenyl-diphosphate phosphatase\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
				},
				{
					"name":"E3D81_09455 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_12365 penicillin-binding protein\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
				},
				{
					"name":"E3D81_07200 mrdA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_07770 PASTA domain-containing protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_01795 dacB; D-alanyl-D-alanine carboxypeptidase\/D-alanyl-D-alanine-endopeptidase\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"E3D81_05555 peptidase S13\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
				},
				{
					"name":"E3D81_08340 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_07750 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_07205 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_03400 hypothetical protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
				},
				{
					"name":"E3D81_07295 peptidase M15\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
				},
				{
					"name":"E3D81_09905 glycoside hydrolase\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
				},
				{
					"name":"E3D81_09895 LysM peptidoglycan-binding domain-containing protein\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
				},
				{
					"name":"E3D81_11405 lytic transglycosylase domain-containing protein\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
				},
				{
					"name":"E3D81_07585 mltG; endolytic transglycosylase MltG\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
				},
				{
					"name":"E3D81_07865 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_07870 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_00235 N-acetylmuramoyl-L-alanine amidase\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_16905 N-acetylmuramoyl-L-alanine amidase\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				}
				]
			},
			{
				"name":"01004 Lipid biosynthesis proteins [BR:sphz01004]",
				"children":[
				{
					"name":"E3D81_16390 fabD; ACP S-malonyltransferase\tK00645 fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
				},
				{
					"name":"E3D81_09155 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_09715 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_12700 3-oxoacyl-ACP synthase III family protein\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_15965 ketoacyl-ACP synthase III\tK00648 fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
				},
				{
					"name":"E3D81_02795 fabF; beta-ketoacyl-[acyl-carrier-protein] synthase II\tK09458 fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
				},
				{
					"name":"E3D81_04715 SDR family NAD(P)-dependent oxidoreductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_13245 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase\tK00059 fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
				},
				{
					"name":"E3D81_15015 bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase\/3-hydroxyacyl-ACP dehydratase\tK16363 lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
				},
				{
					"name":"E3D81_04690 trans-2-enoyl-CoA reductase family protein\tK00209 fabV; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
				},
				{
					"name":"E3D81_11960 arylesterase\tK10804 tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]"
				},
				{
					"name":"E3D81_07150 acyl-ACP desaturase\tK03921 FAB2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
				},
				{
					"name":"E3D81_08550 acs; acetate--CoA ligase\tK01895 ACSS1_2; acetyl-CoA synthetase [EC:6.2.1.1]"
				},
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_09160 plsX; phosphate acyltransferase PlsX\tK03621 plsX; phosphate acyltransferase [EC:2.3.1.274]"
				},
				{
					"name":"E3D81_12985 glycerol-3-phosphate 1-O-acyltransferase\tK08591 plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
				},
				{
					"name":"E3D81_02565 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				},
				{
					"name":"E3D81_08885 1-acyl-sn-glycerol-3-phosphate acyltransferase\tK00655 plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
				}
				]
			},
			{
				"name":"01008 Polyketide biosynthesis proteins [BR:sphz01008]",
				"children":[
				{
					"name":"E3D81_00845 amino acid racemase\tK01779 racD; aspartate racemase [EC:5.1.1.13]"
				}
				]
			},
			{
				"name":"01006 Prenyltransferases [BR:sphz01006]",
				"children":[
				{
					"name":"E3D81_09475 polyprenyl synthetase family protein\tK13789 GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]"
				},
				{
					"name":"E3D81_01635 polyprenyl synthetase family protein\tK02523 ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]"
				},
				{
					"name":"E3D81_07380 isoprenyl transferase\tK00806 uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]"
				},
				{
					"name":"E3D81_14250 phytoene\/squalene synthase family protein\tK02291 crtB; 15-cis-phytoene synthase [EC:2.5.1.32]"
				},
				{
					"name":"E3D81_00705 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"E3D81_08585 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"E3D81_03540 4-hydroxybenzoate octaprenyltransferase\tK03179 ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]"
				},
				{
					"name":"E3D81_08235 cyoE; protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				}
				]
			},
			{
				"name":"01007 Amino acid related enzymes [BR:sphz01007]",
				"children":[
				{
					"name":"E3D81_01465 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"E3D81_14785 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"E3D81_02075 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"E3D81_04730 trpS; tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"E3D81_08480 cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"E3D81_06340 arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"E3D81_08275 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"E3D81_08970 isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"E3D81_07030 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"E3D81_03830 leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"E3D81_04930 lysS; lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"E3D81_07790 aspS; aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"E3D81_02985 asnS; asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"E3D81_02785 histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"E3D81_02315 glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"E3D81_10700 serS; serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"E3D81_11260 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"E3D81_10930 thrS; threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"E3D81_11575 alaS; alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"E3D81_15270 pheS; phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_13090 phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_03565 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_04245 pyridoxal phosphate-dependent aminotransferase\tK00812 aspB; aspartate aminotransferase [EC:2.6.1.1]"
				},
				{
					"name":"E3D81_13155 aminotransferase class I\/II-fold pyridoxal phosphate-dependent enzyme\tK10206 E2.6.1.83; LL-diaminopimelate aminotransferase [EC:2.6.1.83]"
				},
				{
					"name":"E3D81_01740 hisC; histidinol-phosphate transaminase\tK00817 hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]"
				},
				{
					"name":"E3D81_00820 kbl; glycine C-acetyltransferase\tK00639 kbl; glycine C-acetyltransferase [EC:2.3.1.29]"
				},
				{
					"name":"E3D81_00680 pyridoxal phosphate-dependent aminotransferase family protein\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"E3D81_13810 pyridoxal phosphate-dependent aminotransferase family protein\tK00652 bioF; 8-amino-7-oxononanoate synthase [EC:2.3.1.47]"
				},
				{
					"name":"E3D81_01830 pyridoxal phosphate-dependent aminotransferase family protein\tK00654 SPT; serine palmitoyltransferase [EC:2.3.1.50]"
				},
				{
					"name":"E3D81_14520 L-lysine 6-transaminase\tK03918 lat; L-lysine 6-transaminase [EC:2.6.1.36]"
				},
				{
					"name":"E3D81_02615 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme\tK00821 argD; acetylornithine\/N-succinyldiaminopimelate aminotransferase [EC:2.6.1.11 2.6.1.17]"
				},
				{
					"name":"E3D81_13825 bioA; adenosylmethionine--8-amino-7-oxononanoate transaminase\tK00833 bioA; adenosylmethionine---8-amino-7-oxononanoate aminotransferase [EC:2.6.1.62]"
				},
				{
					"name":"E3D81_02395 hemL; glutamate-1-semialdehyde-2,1-aminomutase\tK01845 hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]"
				},
				{
					"name":"E3D81_02165 branched-chain amino acid transaminase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03120 4-amino-4-deoxychorismate lyase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_08600 branched-chain amino acid aminotransferase\tK00826 E2.6.1.42; branched-chain amino acid aminotransferase [EC:2.6.1.42]"
				},
				{
					"name":"E3D81_03450 serC; 3-phosphoserine\/phosphohydroxythreonine transaminase\tK00831 serC; phosphoserine aminotransferase [EC:2.6.1.52]"
				}
				]
			},
			{
				"name":"00199 Cytochrome P450"
			},
			{
				"name":"00194 Photosynthesis proteins [BR:sphz00194]",
				"children":[
				{
					"name":"E3D81_02160 atpC; ATP synthase F1 subunit epsilon\tK02114 ATPF1E; F-type H+-transporting ATPase subunit epsilon"
				},
				{
					"name":"E3D81_02155 F0F1 ATP synthase subunit beta\tK02112 ATPF1B; F-type H+\/Na+-transporting ATPase subunit beta [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"E3D81_09705 atpG; ATP synthase F1 subunit gamma\tK02115 ATPF1G; F-type H+-transporting ATPase subunit gamma"
				},
				{
					"name":"E3D81_09700 F0F1 ATP synthase subunit alpha\tK02111 ATPF1A; F-type H+\/Na+-transporting ATPase subunit alpha [EC:7.1.2.2 7.2.2.1]"
				},
				{
					"name":"E3D81_09695 atpH; ATP synthase F1 subunit delta\tK02113 ATPF1D; F-type H+-transporting ATPase subunit delta"
				},
				{
					"name":"E3D81_09690 F0F1 ATP synthase subunit B\tK02109 ATPF0B; F-type H+-transporting ATPase subunit b"
				},
				{
					"name":"E3D81_09685 atpE; ATP synthase F0 subunit C\tK02110 ATPF0C; F-type H+-transporting ATPase subunit c"
				},
				{
					"name":"E3D81_09680 atpB; F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				}
				]
			}
			]
		},
		{
			"name":"09182 Protein families: genetic information processing",
			"children":[
			{
				"name":"03000 Transcription factors [BR:sphz03000]",
				"children":[
				{
					"name":"E3D81_05185 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"E3D81_04335 helix-turn-helix domain-containing protein\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"E3D81_05425 helix-turn-helix domain-containing protein\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"E3D81_15390 AraC family transcriptional regulator\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"E3D81_16145 AraC family transcriptional regulator\tK18954 pobR; AraC family transcriptional regulator, transcriptional activator of pobA"
				},
				{
					"name":"E3D81_09840 methylated-DNA--[protein]-cysteine S-methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"E3D81_03510 hydrogen peroxide-inducible genes activator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"E3D81_10950 DeoR\/GlpR transcriptional regulator\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				},
				{
					"name":"E3D81_00645 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_02380 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_06050 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_08085 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_08180 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_13160 LacI family DNA-binding transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_14440 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_14455 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_15150 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"E3D81_13800 PLP-dependent aminotransferase family protein\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"E3D81_11190 TetR\/AcrR family transcriptional regulator\tK18136 acrR; TetR\/AcrR family transcriptional regulator, multidrug resistance operon repressor"
				},
				{
					"name":"E3D81_06715 TetR\/AcrR family transcriptional regulator\tK09017 rutR; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"E3D81_02590 winged helix-turn-helix transcriptional regulator\tK03718 asnC; Lrp\/AsnC family transcriptional regulator, regulator for asnA, asnC and gidA"
				},
				{
					"name":"E3D81_00915 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"E3D81_12915 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"E3D81_14680 MarR family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				},
				{
					"name":"E3D81_03885 transcriptional repressor\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"E3D81_10205 transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"E3D81_11825 transcriptional repressor\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"E3D81_16715 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"E3D81_10575 Crp\/Fnr family transcriptional regulator\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"E3D81_11900 Crp\/Fnr family transcriptional regulator\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"E3D81_15790 Crp\/Fnr family transcriptional regulator\tK21562 flp; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				},
				{
					"name":"E3D81_10170 transcriptional regulator\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"E3D81_05890 PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"E3D81_10535 PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"E3D81_16550 PadR family transcriptional regulator\tK10947 K10947; PadR family transcriptional regulator"
				},
				{
					"name":"E3D81_00735 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_02045 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03715 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03730 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_09065 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_01045 biotin--[acetyl-CoA-carboxylase] ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"E3D81_04890 transcriptional regulator\tK07727 K07727; putative transcriptional regulator"
				},
				{
					"name":"E3D81_01400 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"E3D81_08130 ROK family transcriptional regulator\tK02565 nagC; N-acetylglucosamine repressor"
				},
				{
					"name":"E3D81_13350 ROK family protein\tK15545 mlc; transcriptional regulator of PTS gene"
				},
				{
					"name":"E3D81_01955 pyrR; bifunctional pyr operon transcriptional regulator\/uracil phosphoribosyltransferase PyrR\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"E3D81_09900 phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"E3D81_13360 YqgE\/AlgH family protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"E3D81_08965 TraR\/DksA family transcriptional regulator\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"E3D81_07785 mraZ; division\/cell wall cluster transcriptional repressor MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			},
			{
				"name":"03021 Transcription machinery [BR:sphz03021]",
				"children":[
				{
					"name":"E3D81_02625 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_09325 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_09330 rpoC; DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_04895 RNA polymerase sigma factor RpoD\/SigA\tK03086 rpoD; RNA polymerase primary sigma factor"
				},
				{
					"name":"E3D81_00975 sigma-70 family RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"E3D81_06935 sigma-70 family RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"E3D81_09960 RNA polymerase sigma factor\tK03088 rpoE; RNA polymerase sigma-70 factor, ECF subfamily"
				},
				{
					"name":"E3D81_02120 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_05150 sigma-70 family RNA polymerase sigma factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_08825 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_13210 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_16355 RNA polymerase sigma-70 factor\tK23514 fecI; RNA polymerase sigma-19 factor, ECF subfamily"
				},
				{
					"name":"E3D81_12360 rpoN; RNA polymerase factor sigma-54\tK03092 rpoN; RNA polymerase sigma-54 factor"
				},
				{
					"name":"E3D81_12390 nusA; transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"E3D81_06890 nusB; transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"E3D81_09300 nusG; transcription termination\/antitermination factor NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"E3D81_01730 anti-anti-sigma factor\tK04749 rsbV; anti-sigma B factor antagonist"
				},
				{
					"name":"E3D81_08965 TraR\/DksA family transcriptional regulator\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"E3D81_10765 greA; transcription elongation factor GreA\tK03624 greA; transcription elongation factor GreA"
				},
				{
					"name":"E3D81_07515 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				}
				]
			},
			{
				"name":"03019 Messenger RNA biogenesis [BR:sphz03019]",
				"children":[
				{
					"name":"E3D81_00695 Rne\/Rng family ribonuclease\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
				},
				{
					"name":"E3D81_02790 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"E3D81_13105 rny; ribonuclease Y\tK18682 rny; ribonucrease Y [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_11820 rnr; ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"E3D81_08915 DEAD\/DEAH box helicase\tK11927 rhlE; ATP-dependent RNA helicase RhlE [EC:5.6.2.7]"
				},
				{
					"name":"E3D81_11530 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"E3D81_03580 recQ; DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_07655 RecQ family ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"E3D81_08155 pnp; polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				},
				{
					"name":"E3D81_07515 transcription termination factor Rho\tK03628 rho; transcription termination factor Rho"
				},
				{
					"name":"E3D81_01030 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_06725 pfkA; 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"E3D81_03955 ppk1; polyphosphate kinase 1\tK00937 ppk1; polyphosphate kinase [EC:2.7.4.1]"
				}
				]
			},
			{
				"name":"03041 Spliceosome"
			},
			{
				"name":"03011 Ribosome [BR:sphz03011]",
				"children":[
				{
					"name":"E3D81_07605 30S ribosomal protein S1\tK02945 RP-S1; small subunit ribosomal protein S1"
				},
				{
					"name":"E3D81_09860 rpsB; 30S ribosomal protein S2\tK02967 RP-S2; small subunit ribosomal protein S2"
				},
				{
					"name":"E3D81_02730 rpsC; 30S ribosomal protein S3\tK02982 RP-S3; small subunit ribosomal protein S3"
				},
				{
					"name":"E3D81_02630 rpsD; 30S ribosomal protein S4\tK02986 RP-S4; small subunit ribosomal protein S4"
				},
				{
					"name":"E3D81_02675 30S ribosomal protein S5\tK02988 RP-S5; small subunit ribosomal protein S5"
				},
				{
					"name":"E3D81_04250 30S ribosomal protein S6\tK02990 RP-S6; small subunit ribosomal protein S6"
				},
				{
					"name":"E3D81_11810 rpsG; 30S ribosomal protein S7\tK02992 RP-S7; small subunit ribosomal protein S7"
				},
				{
					"name":"E3D81_02690 rpsH; 30S ribosomal protein S8\tK02994 RP-S8; small subunit ribosomal protein S8"
				},
				{
					"name":"E3D81_09865 rpsI; 30S ribosomal protein S9\tK02996 RP-S9; small subunit ribosomal protein S9"
				},
				{
					"name":"E3D81_11800 rpsJ; 30S ribosomal protein S10\tK02946 RP-S10; small subunit ribosomal protein S10"
				},
				{
					"name":"E3D81_02635 rpsK; 30S ribosomal protein S11\tK02948 RP-S11; small subunit ribosomal protein S11"
				},
				{
					"name":"E3D81_11815 30S ribosomal protein S12\tK02950 RP-S12; small subunit ribosomal protein S12"
				},
				{
					"name":"E3D81_02640 rpsM; 30S ribosomal protein S13\tK02952 RP-S13; small subunit ribosomal protein S13"
				},
				{
					"name":"E3D81_02695 rpsN; 30S ribosomal protein S14\tK02954 RP-S14; small subunit ribosomal protein S14"
				},
				{
					"name":"E3D81_08140 rpsO; 30S ribosomal protein S15\tK02956 RP-S15; small subunit ribosomal protein S15"
				},
				{
					"name":"E3D81_14810 30S ribosomal protein S16\tK02959 RP-S16; small subunit ribosomal protein S16"
				},
				{
					"name":"E3D81_02715 rpsQ; 30S ribosomal protein S17\tK02961 RP-S17; small subunit ribosomal protein S17"
				},
				{
					"name":"E3D81_04255 rpsR; 30S ribosomal protein S18\tK02963 RP-S18; small subunit ribosomal protein S18"
				},
				{
					"name":"E3D81_02740 rpsS; 30S ribosomal protein S19\tK02965 RP-S19; small subunit ribosomal protein S19"
				},
				{
					"name":"E3D81_07990 30S ribosomal protein S20\tK02968 RP-S20; small subunit ribosomal protein S20"
				},
				{
					"name":"E3D81_05010 30S ribosomal protein S21\tK02970 RP-S21; small subunit ribosomal protein S21"
				},
				{
					"name":"E3D81_09310 50S ribosomal protein L1\tK02863 RP-L1; large subunit ribosomal protein L1"
				},
				{
					"name":"E3D81_02745 rplB; 50S ribosomal protein L2\tK02886 RP-L2; large subunit ribosomal protein L2"
				},
				{
					"name":"E3D81_02760 50S ribosomal protein L3\tK02906 RP-L3; large subunit ribosomal protein L3"
				},
				{
					"name":"E3D81_02755 rplD; 50S ribosomal protein L4\tK02926 RP-L4; large subunit ribosomal protein L4"
				},
				{
					"name":"E3D81_02700 rplE; 50S ribosomal protein L5\tK02931 RP-L5; large subunit ribosomal protein L5"
				},
				{
					"name":"E3D81_02685 50S ribosomal protein L6\tK02933 RP-L6; large subunit ribosomal protein L6"
				},
				{
					"name":"E3D81_04260 50S ribosomal protein L9\tK02939 RP-L9; large subunit ribosomal protein L9"
				},
				{
					"name":"E3D81_09315 50S ribosomal protein L10\tK02864 RP-L10; large subunit ribosomal protein L10"
				},
				{
					"name":"E3D81_09305 rplK; 50S ribosomal protein L11\tK02867 RP-L11; large subunit ribosomal protein L11"
				},
				{
					"name":"E3D81_09320 50S ribosomal protein L7\/L12\tK02935 RP-L7; large subunit ribosomal protein L7\/L12"
				},
				{
					"name":"E3D81_09870 rplM; 50S ribosomal protein L13\tK02871 RP-L13; large subunit ribosomal protein L13"
				},
				{
					"name":"E3D81_02710 rplN; 50S ribosomal protein L14\tK02874 RP-L14; large subunit ribosomal protein L14"
				},
				{
					"name":"E3D81_02665 50S ribosomal protein L15\tK02876 RP-L15; large subunit ribosomal protein L15"
				},
				{
					"name":"E3D81_02725 rplP; 50S ribosomal protein L16\tK02878 RP-L16; large subunit ribosomal protein L16"
				},
				{
					"name":"E3D81_02620 50S ribosomal protein L17\tK02879 RP-L17; large subunit ribosomal protein L17"
				},
				{
					"name":"E3D81_02680 50S ribosomal protein L18\tK02881 RP-L18; large subunit ribosomal protein L18"
				},
				{
					"name":"E3D81_10020 50S ribosomal protein L19\tK02884 RP-L19; large subunit ribosomal protein L19"
				},
				{
					"name":"E3D81_10945 rplT; 50S ribosomal protein L20\tK02887 RP-L20; large subunit ribosomal protein L20"
				},
				{
					"name":"E3D81_06925 rplU; 50S ribosomal protein L21\tK02888 RP-L21; large subunit ribosomal protein L21"
				},
				{
					"name":"E3D81_02735 50S ribosomal protein L22\tK02890 RP-L22; large subunit ribosomal protein L22"
				},
				{
					"name":"E3D81_02750 50S ribosomal protein L23\tK02892 RP-L23; large subunit ribosomal protein L23"
				},
				{
					"name":"E3D81_02705 50S ribosomal protein L24\tK02895 RP-L24; large subunit ribosomal protein L24"
				},
				{
					"name":"E3D81_06920 50S ribosomal protein L27\tK02899 RP-L27; large subunit ribosomal protein L27"
				},
				{
					"name":"E3D81_16985 50S ribosomal protein L28\tK02902 RP-L28; large subunit ribosomal protein L28"
				},
				{
					"name":"E3D81_02720 50S ribosomal protein L29\tK02904 RP-L29; large subunit ribosomal protein L29"
				},
				{
					"name":"E3D81_02670 rpmD; 50S ribosomal protein L30\tK02907 RP-L30; large subunit ribosomal protein L30"
				},
				{
					"name":"E3D81_04925 type B 50S ribosomal protein L31\tK02909 RP-L31; large subunit ribosomal protein L31"
				},
				{
					"name":"E3D81_09165 rpmF; 50S ribosomal protein L32\tK02911 RP-L32; large subunit ribosomal protein L32"
				},
				{
					"name":"E3D81_16980 rpmG; 50S ribosomal protein L33\tK02913 RP-L33; large subunit ribosomal protein L33"
				},
				{
					"name":"E3D81_07700 50S ribosomal protein L34\tK02914 RP-L34; large subunit ribosomal protein L34"
				},
				{
					"name":"E3D81_10940 rpmI; 50S ribosomal protein L35\tK02916 RP-L35; large subunit ribosomal protein L35"
				},
				{
					"name":"E3D81_02645 50S ribosomal protein L36\tK02919 RP-L36; large subunit ribosomal protein L36"
				},
				{
					"name":"E3D81_02015 50S ribosomal protein L25\/general stress protein Ctc\tK02897 RP-L25; large subunit ribosomal protein L25"
				},
				{
					"name":"E3D81_00740 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_11365 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_00755 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_11380 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_00760 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_03070 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_08105 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_11385 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				}
				]
			},
			{
				"name":"03009 Ribosome biogenesis [BR:sphz03009]",
				"children":[
				{
					"name":"E3D81_02790 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"E3D81_08635 GTPase Era\tK03595 era; GTPase"
				},
				{
					"name":"E3D81_06195 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
				},
				{
					"name":"E3D81_08965 TraR\/DksA family transcriptional regulator\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"E3D81_12390 nusA; transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
				},
				{
					"name":"E3D81_06890 nusB; transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
				},
				{
					"name":"E3D81_09300 nusG; transcription termination\/antitermination factor NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
				},
				{
					"name":"E3D81_08565 rsmA; 16S rRNA (adenine(1518)-N(6)\/adenine(1519)-N(6))-dimethyltransferase RsmA\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"E3D81_05825 RsmB\/NOP family class I SAM-dependent RNA methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"E3D81_05490 rsmD; 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"E3D81_10795 16S rRNA (uracil(1498)-N(3))-methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"E3D81_08450 rsmG; 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"E3D81_07780 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"E3D81_00080 SAM-dependent methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"E3D81_10875 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"E3D81_07995 TrmH family RNA methyltransferase\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"E3D81_11520 rlmB; 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"E3D81_06815 rlmF; 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"E3D81_07265 rlmH; 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"E3D81_09645 oxidoreductase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"E3D81_09935 class I SAM-dependent rRNA methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"E3D81_14665 class I SAM-dependent RNA methyltransferase\tK25137 rlmL; 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.173]"
				},
				{
					"name":"E3D81_16565 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"E3D81_15260 rlmD; 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"E3D81_03415 RluA family pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"E3D81_11400 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"E3D81_06490 RluA family pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"E3D81_03115 RluA family pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"E3D81_10735 RluA family pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"E3D81_11005 rimK; 30S ribosomal protein S6--L-glutamate ligase\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
				},
				{
					"name":"E3D81_06015 N-acetyltransferase\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]"
				},
				{
					"name":"E3D81_14805 rimM; 16S rRNA processing protein RimM\tK02860 rimM; 16S rRNA processing protein RimM"
				},
				{
					"name":"E3D81_16965 rimO; 30S ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
				},
				{
					"name":"E3D81_04910 50S ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"E3D81_00695 Rne\/Rng family ribonuclease\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
				},
				{
					"name":"E3D81_15855 ruvX; Holliday junction resolvase RuvX\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_11530 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
				},
				{
					"name":"E3D81_16435 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
				},
				{
					"name":"E3D81_08475 ribosome biogenesis GTPase Der\tK03977 engA; GTPase"
				},
				{
					"name":"E3D81_01270 hflX; GTPase HflX\tK03665 hflX; GTPase"
				},
				{
					"name":"E3D81_08295 threonylcarbamoyl-AMP synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"E3D81_03880 bifunctional (p)ppGpp synthetase\/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
				},
				{
					"name":"E3D81_02945 rbfA; 30S ribosome-binding factor RbfA\tK02834 rbfA; ribosome-binding factor A"
				},
				{
					"name":"E3D81_12385 rimP; ribosome assembly cofactor RimP\tK09748 rimP; ribosome maturation factor RimP"
				},
				{
					"name":"E3D81_05570 RNA-binding S4 domain-containing protein\tK14761 rlbA; ribosome-associated protein"
				},
				{
					"name":"E3D81_01050 rsfS; ribosome silencing factor\tK09710 ybeB; ribosome-associated protein"
				},
				{
					"name":"E3D81_15850 ybeY; rRNA maturation RNase YbeY\tK07042 ybeY; probable rRNA maturation factor"
				},
				{
					"name":"E3D81_13415 raiA; ribosome-associated translation inhibitor RaiA\tK05808 hpf; ribosome hibernation promoting factor"
				},
				{
					"name":"E3D81_05815 ychF; redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
				},
				{
					"name":"E3D81_09170 DUF177 domain-containing protein\tK07040 yceD; DUF177 domain-containing protein"
				}
				]
			},
			{
				"name":"03016 Transfer RNA biogenesis [BR:sphz03016]",
				"children":[
				{
					"name":"E3D81_01735 ribonuclease Z\tK00784 rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"E3D81_08575 HD domain-containing protein\tK00974 cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				},
				{
					"name":"E3D81_05995 RtcB family protein\tK14415 RTCB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"E3D81_01465 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"E3D81_11260 proline--tRNA ligase\tK01881 PARS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"E3D81_08970 isoleucine--tRNA ligase\tK01870 IARS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"E3D81_03830 leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"E3D81_08275 metG; methionine--tRNA ligase\tK01874 MARS; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"E3D81_14785 glutamine--tRNA ligase\/YqeY domain fusion protein\tK01886 QARS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"E3D81_06340 arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"E3D81_04930 lysS; lysine--tRNA ligase\tK04567 KARS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"E3D81_07790 aspS; aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"E3D81_11575 alaS; alanine--tRNA ligase\tK01872 AARS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"E3D81_02985 asnS; asparagine--tRNA ligase\tK01893 NARS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"E3D81_02315 glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"E3D81_10930 thrS; threonine--tRNA ligase\tK01868 TARS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"E3D81_10700 serS; serine--tRNA ligase\tK01875 SARS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"E3D81_08480 cysteine--tRNA ligase\tK01883 CARS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"E3D81_07030 valine--tRNA ligase\tK01873 VARS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"E3D81_02785 histidine--tRNA ligase\tK01892 HARS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"E3D81_15270 pheS; phenylalanine--tRNA ligase subunit alpha\tK01889 FARSA; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_13090 phenylalanine--tRNA ligase subunit beta\tK01890 FARSB; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"E3D81_02075 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"E3D81_04730 trpS; tryptophan--tRNA ligase\tK01867 WARS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"E3D81_14950 D-tyrosyl-tRNA(Tyr) deacylase\tK07560 dtd; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"E3D81_10770 HIT family protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"E3D81_15240 miaB; tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB\tK06168 CDK5RAP1; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"E3D81_11480 mtaB; tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase MtaB\tK15865 CDKAL1; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				},
				{
					"name":"E3D81_01095 trmB; tRNA (guanosine(46)-N7)-methyltransferase TrmB\tK03439 trmB; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"E3D81_00870 truA; tRNA pseudouridine(38-40) synthase TruA\tK06173 truA; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"E3D81_03850 truB; tRNA pseudouridine(55) synthase TruB\tK03177 truB; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"E3D81_10860 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_13725 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_08295 threonylcarbamoyl-AMP synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"E3D81_00705 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"E3D81_08585 miaA; tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA\tK00791 miaA; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"E3D81_13980 mnmE; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE\tK03650 mnmE; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"E3D81_00065 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"E3D81_07695 rnpA; ribonuclease P protein component\tK03536 rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"E3D81_06305 rnpB; RNase P RNA component class A\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"E3D81_11310 ettA; energy-dependent translational throttle protein EttA\tK06020 ettA; energy-dependent translational throttle protein EttA"
				},
				{
					"name":"E3D81_02470 nucleoside deaminase\tK11991 tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				},
				{
					"name":"E3D81_14925 dusB; tRNA dihydrouridine synthase DusB\tK05540 dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				},
				{
					"name":"E3D81_14905 trmD; tRNA (guanosine(37)-N1)-methyltransferase TrmD\tK00554 trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"E3D81_08350 methyltransferase domain-containing protein\tK15460 yfiC; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]"
				},
				{
					"name":"E3D81_10685 RNA methyltransferase\tK03437 spoU; RNA methyltransferase, TrmH family"
				},
				{
					"name":"E3D81_17020 pseudouridylate synthase\tK06175 truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]"
				},
				{
					"name":"E3D81_03415 RluA family pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"E3D81_06740 mnmA; tRNA 2-thiouridine(34) synthase MnmA\tK00566 mnmA; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"E3D81_08975 iron-sulfur cluster assembly accessory protein\tK13628 iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"E3D81_13720 iron-sulfur cluster assembly accessory protein\tK13628 iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"E3D81_16580 tRNA-(ms[2]io[6]A)-hydroxylase\tK06169 miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]"
				},
				{
					"name":"E3D81_12885 queA; tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA\tK07568 queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"E3D81_00200 6-carboxytetrahydropterin synthase\tK01737 queD; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"E3D81_10915 7-carboxy-7-deazaguanine synthase QueE\tK10026 queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"E3D81_09175 epoxyqueuosine reductase QueH\tK09765 queH; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"E3D81_08460 tgt; tRNA guanosine(34) transglycosylase Tgt\tK00773 tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"E3D81_03030 tilS; tRNA lysidine(34) synthetase TilS\tK04075 tilS; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"E3D81_07685 tsaB; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB\tK14742 tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"E3D81_07815 tsaD; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD\tK25706 tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"E3D81_15035 tsaE; tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE\tK06925 tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"E3D81_13690 tRNA threonylcarbamoyladenosine dehydratase\tK22132 tcdA; tRNA threonylcarbamoyladenosine dehydratase"
				},
				{
					"name":"E3D81_11820 rnr; ribonuclease R\tK12573 rnr; ribonuclease R [EC:3.1.13.1]"
				},
				{
					"name":"E3D81_08155 pnp; polyribonucleotide nucleotidyltransferase\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
				}
				]
			},
			{
				"name":"03012 Translation factors [BR:sphz03012]",
				"children":[
				{
					"name":"E3D81_16340 translation initiation factor\tK03113 EIF1; translation initiation factor 1"
				},
				{
					"name":"E3D81_12395 infB; translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"E3D81_10935 translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"E3D81_05785 ABC transporter ATP-binding protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"E3D81_14420 ABC-F family ATP-binding cassette domain-containing protein\tK06158 ABCF3; ATP-binding cassette, subfamily F, member 3"
				},
				{
					"name":"E3D81_09855 elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"E3D81_09285 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"E3D81_11805 fusA; elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"E3D81_01595 peptide chain release factor 1\tK02835 prfA; peptide chain release factor 1"
				},
				{
					"name":"E3D81_09045 ribosome recycling factor\tK02838 frr; ribosome recycling factor"
				},
				{
					"name":"E3D81_12815 prmC; peptide chain release factor N(5)-glutamine methyltransferase\tK02493 hemK; release factor glutamine methyltransferase [EC:2.1.1.297]"
				},
				{
					"name":"E3D81_02030 aminoacyl-tRNA hydrolase\tK01056 PTH1; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]"
				},
				{
					"name":"E3D81_02650 infA; translation initiation factor IF-1\tK02518 infA; translation initiation factor IF-1"
				},
				{
					"name":"E3D81_15000 efp; elongation factor P\tK02356 efp; elongation factor P"
				},
				{
					"name":"E3D81_16190 peptide chain release factor 2\tK02836 prfB; peptide chain release factor 2"
				},
				{
					"name":"E3D81_09060 aminoacyl-tRNA hydrolase\tK15034 yaeJ; ribosome-associated protein"
				}
				]
			},
			{
				"name":"03110 Chaperones and folding catalysts [BR:sphz03110]",
				"children":[
				{
					"name":"E3D81_03485 clpB; ATP-dependent chaperone ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
				},
				{
					"name":"E3D81_11305 ATP-dependent Clp protease ATP-binding subunit\tK03696 clpC; ATP-dependent Clp protease ATP-binding subunit ClpC"
				},
				{
					"name":"E3D81_11155 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
				},
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"E3D81_03595 dnaJ; molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"E3D81_09095 J domain-containing protein\tK05516 cbpA; curved DNA-binding protein"
				},
				{
					"name":"E3D81_03600 nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"E3D81_07060 Hsp20\/alpha crystallin family protein\tK13993 HSP20; HSP20 family protein"
				},
				{
					"name":"E3D81_08305 RNA-binding S4 domain-containing protein\tK04762 hslR; ribosome-associated heat shock protein Hsp15"
				},
				{
					"name":"E3D81_15215 co-chaperone GroES\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"E3D81_01485 Do family serine endopeptidase\tK04771 degP; serine protease Do [EC:3.4.21.107]"
				},
				{
					"name":"E3D81_01055 hflB; ATP-dependent zinc metalloprotease FtsH\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
				},
				{
					"name":"E3D81_09680 atpB; F0F1 ATP synthase subunit A\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
				},
				{
					"name":"E3D81_17155 hypothetical protein\tK06006 cpxP; periplasmic protein CpxP\/Spy"
				},
				{
					"name":"E3D81_02430 peptidase S8\tK13274 wprA; cell wall-associated protease [EC:3.4.21.-]"
				},
				{
					"name":"E3D81_08735 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_15090 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
				},
				{
					"name":"E3D81_06620 peptidylprolyl isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_01655 peptidylprolyl isomerase\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_01900 peptidylprolyl isomerase\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_04750 FKBP-type peptidyl-prolyl cis-trans isomerase\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_09535 peptidylprolyl isomerase\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_08490 peptidylprolyl isomerase\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				},
				{
					"name":"E3D81_00260 thioredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"E3D81_03310 trxA; thioredoxin\tK03671 TXN; thioredoxin"
				},
				{
					"name":"E3D81_04770 trxA; thioredoxin\tK03671 TXN; thioredoxin"
				}
				]
			},
			{
				"name":"04131 Membrane trafficking [BR:sphz04131]",
				"children":[
				{
					"name":"E3D81_15565 nucleoside-diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"E3D81_06180 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_06735 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_15360 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_02810 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"E3D81_05550 MFS transporter\tK06902 UMF1; MFS transporter, UMF1 family"
				}
				]
			},
			{
				"name":"04121 Ubiquitin system"
			},
			{
				"name":"03051 Proteasome [BR:sphz03051]",
				"children":[
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"03032 DNA replication proteins [BR:sphz03032]",
				"children":[
				{
					"name":"E3D81_06400 rnhA; ribonuclease HI\tK03469 rnhA; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"E3D81_05185 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"E3D81_00685 integration host factor subunit beta\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"E3D81_00005 dnaA; chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"E3D81_04505 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"E3D81_07315 dnaB; replicative DNA helicase\tK02314 dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"E3D81_15905 DNA primase\tK02316 dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_04775 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17125 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11140 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17130 hypothetical protein\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_03905 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_13070 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16105 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11515 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16410 ribonuclease HII\tK03470 rnhB; ribonuclease HII [EC:3.1.26.4]"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"E3D81_00110 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_05320 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_03445 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_07670 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_10630 DNA gyrase\/topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_09655 type IIA DNA topoisomerase subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_03545 topA; type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"E3D81_12570 DNA topoisomerase IB\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"E3D81_02920 type IA DNA topoisomerase\tK03169 topB; DNA topoisomerase III [EC:5.6.2.1]"
				},
				{
					"name":"E3D81_10465 type IA DNA topoisomerase\tK03169 topB; DNA topoisomerase III [EC:5.6.2.1]"
				}
				]
			},
			{
				"name":"03036 Chromosome and associated proteins [BR:sphz03036]",
				"children":[
				{
					"name":"E3D81_05185 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"E3D81_02790 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				},
				{
					"name":"E3D81_00685 integration host factor subunit beta\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"E3D81_09095 J domain-containing protein\tK05516 cbpA; curved DNA-binding protein"
				},
				{
					"name":"E3D81_00005 dnaA; chromosomal replication initiator protein DnaA\tK02313 dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"E3D81_03425 DNA starvation\/stationary phase protection protein\tK04047 dps; starvation-inducible DNA-binding protein"
				},
				{
					"name":"E3D81_00915 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"E3D81_12915 Lrp\/AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"E3D81_13765 smc; chromosome segregation protein SMC\tK03529 smc; chromosome segregation protein"
				},
				{
					"name":"E3D81_00015 chromosome segregation protein ScpA\tK05896 scpA; segregation and condensation protein A"
				},
				{
					"name":"E3D81_13445 scpB; SMC-Scp complex subunit ScpB\tK06024 scpB; segregation and condensation protein B"
				},
				{
					"name":"E3D81_07730 ftsA; cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"E3D81_03605 ATP-binding cassette domain-containing protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"E3D81_07770 PASTA domain-containing protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
				},
				{
					"name":"E3D81_02090 DNA translocase FtsK\tK03466 ftsK; DNA segregation ATPase FtsK\/SpoIIIE, S-DNA-T family"
				},
				{
					"name":"E3D81_07735 cell division protein FtsQ\tK03589 ftsQ; cell division protein FtsQ"
				},
				{
					"name":"E3D81_07750 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_03835 FtsX-like permease family protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"E3D81_07725 ftsZ; cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"E3D81_13100 cell division protein ZapA\tK09888 zapA; cell division protein ZapA"
				},
				{
					"name":"E3D81_07865 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_07870 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
				},
				{
					"name":"E3D81_05060 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06705 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_08695 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11180 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11350 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11920 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12235 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07185 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"E3D81_07190 mreC; rod shape-determining protein MreC\tK03570 mreC; rod shape-determining protein MreC"
				},
				{
					"name":"E3D81_07205 rodA; rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_01395 ParA family protein\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"E3D81_05200 ParA family protein\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"E3D81_01400 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"E3D81_10630 DNA gyrase\/topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_09655 type IIA DNA topoisomerase subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_00065 mnmG; tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG\tK03495 gidA; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"E3D81_08450 rsmG; 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"E3D81_13410 integrase\tK03733 xerC; integrase\/recombinase XerC"
				},
				{
					"name":"E3D81_04940 xerD; site-specific tyrosine recombinase XerD\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_10030 recombinase\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_10045 integrase\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_10485 recombinase\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_10510 integrase\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_11635 recombinase\tK04763 xerD; integrase\/recombinase XerD"
				},
				{
					"name":"E3D81_14860 iron-sulfur cluster carrier protein ApbC\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"E3D81_09810 Fic family protein\tK04095 fic; cell filamentation protein, protein adenylyltransferase [EC:2.7.7.108]"
				},
				{
					"name":"E3D81_03535 YihA family ribosome biogenesis GTP-binding protein\tK03978 engB; GTP-binding protein"
				}
				]
			},
			{
				"name":"03400 DNA repair and recombination proteins [BR:sphz03400]",
				"children":[
				{
					"name":"E3D81_12505 deoxyribodipyrimidine photo-lyase\tK01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]"
				},
				{
					"name":"E3D81_00905 uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
				},
				{
					"name":"E3D81_15280 mutY; A\/G-specific adenine glycosylase\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
				},
				{
					"name":"E3D81_02435 nth; endonuclease III\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
				},
				{
					"name":"E3D81_06570 S1\/P1 Nuclease\tK05986 NUCS; nuclease S1 [EC:3.1.30.1]"
				},
				{
					"name":"E3D81_06525 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"E3D81_07260 NUDIX domain-containing protein\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"E3D81_12315 (deoxy)nucleoside triphosphate pyrophosphohydrolase\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"E3D81_09840 methylated-DNA--[protein]-cysteine S-methyltransferase\tK10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response \/ methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"E3D81_14845 DNA-3-methyladenine glycosylase I\tK01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]"
				},
				{
					"name":"E3D81_01505 xth; exodeoxyribonuclease III\tK01142 xthA; exodeoxyribonuclease III [EC:3.1.11.2]"
				},
				{
					"name":"E3D81_08615 recJ; single-stranded-DNA-specific exonuclease RecJ\tK07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_06270 ligA; DNA ligase (NAD(+)) LigA\tK01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]"
				},
				{
					"name":"E3D81_16440 polA; DNA polymerase I\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_01010 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"E3D81_02900 uvrA; excinuclease ABC subunit UvrA\tK03701 uvrA; excinuclease ABC subunit A"
				},
				{
					"name":"E3D81_08795 uvrB; excinuclease ABC subunit UvrB\tK03702 uvrB; excinuclease ABC subunit B"
				},
				{
					"name":"E3D81_09460 excinuclease ABC subunit C\tK03703 uvrC; excinuclease ABC subunit C"
				},
				{
					"name":"E3D81_07285 ATP-dependent DNA helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_13605 ATP-dependent helicase\tK03657 uvrD; ATP-dependent DNA helicase UvrD\/PcrA [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_09325 rpoB; DNA-directed RNA polymerase subunit beta\tK03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_09330 rpoC; DNA-directed RNA polymerase subunit beta'\tK03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_02625 DNA-directed RNA polymerase subunit alpha\tK03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]"
				},
				{
					"name":"E3D81_15400 mfd; transcription-repair coupling factor\tK03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_08345 mutS; DNA mismatch repair protein MutS\tK03555 mutS; DNA mismatch repair protein MutS"
				},
				{
					"name":"E3D81_13310 endonuclease MutS2\tK07456 mutS2; DNA mismatch repair protein MutS2"
				},
				{
					"name":"E3D81_14525 mutL; DNA mismatch repair endonuclease MutL\tK03572 mutL; DNA mismatch repair protein MutL"
				},
				{
					"name":"E3D81_00995 xseA; exodeoxyribonuclease VII large subunit\tK03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]"
				},
				{
					"name":"E3D81_01000 xseB; exodeoxyribonuclease VII small subunit\tK03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]"
				},
				{
					"name":"E3D81_04775 dnaE; DNA polymerase III subunit alpha\tK02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17125 dnaN; DNA polymerase III subunit beta\tK02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11140 holA; DNA polymerase III subunit delta\tK02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_17130 hypothetical protein\tK02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_03905 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_13070 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_16105 DNA polymerase III subunit epsilon\tK02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_11515 DNA polymerase III subunit gamma\/tau\tK02343 dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_00110 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_05320 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_14110 very short patch repair endonuclease\tK07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_02440 recA; recombinase RecA\tK03553 recA; recombination protein RecA"
				},
				{
					"name":"E3D81_01785 ruvA; Holliday junction branch migration protein RuvA\tK03550 ruvA; holliday junction DNA helicase RuvA"
				},
				{
					"name":"E3D81_05515 ruvB; Holliday junction branch migration DNA helicase RuvB\tK03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_02580 ruvC; crossover junction endodeoxyribonuclease RuvC\tK01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]"
				},
				{
					"name":"E3D81_01880 priA; primosomal protein N'\tK04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_05870 SMC family ATPase\tK03546 sbcC; DNA repair protein SbcC\/Rad50"
				},
				{
					"name":"E3D81_05865 sbcD; exonuclease subunit SbcD\tK03547 sbcD; DNA repair protein SbcD\/Mre11"
				},
				{
					"name":"E3D81_00970 radA; DNA repair protein RadA\tK04485 radA; DNA repair protein RadA\/Sms"
				},
				{
					"name":"E3D81_03015 recF; DNA replication and repair protein RecF\tK03629 recF; DNA replication and repair protein RecF"
				},
				{
					"name":"E3D81_01275 recG; ATP-dependent DNA helicase RecG\tK03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_16995 recO; DNA repair protein RecO\tK03584 recO; DNA repair protein RecO (recombination protein O)"
				},
				{
					"name":"E3D81_13330 recR; recombination protein RecR\tK06187 recR; recombination protein RecR"
				},
				{
					"name":"E3D81_11295 recN; DNA repair protein RecN\tK03631 recN; DNA repair protein RecN (Recombination protein N)"
				},
				{
					"name":"E3D81_14815 Dna2\/Cas4 domain-containing protein\tK16898 addA; ATP-dependent helicase\/nuclease subunit A [EC:5.6.2.4 3.1.-.-]"
				},
				{
					"name":"E3D81_14760 DUF853 family protein\tK06915 herA; DNA double-strand break repair helicase HerA and related ATPase"
				},
				{
					"name":"E3D81_12540 Ku protein\tK10979 ku; DNA end-binding protein Ku"
				},
				{
					"name":"E3D81_12535 ligD; DNA ligase D\tK01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]"
				},
				{
					"name":"E3D81_03445 gyrA; DNA gyrase subunit A\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_07670 gyrB; DNA topoisomerase (ATP-hydrolyzing) subunit B\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_03545 topA; type I DNA topoisomerase\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"E3D81_12570 DNA topoisomerase IB\tK03168 topA; DNA topoisomerase I [EC:5.6.2.1]"
				},
				{
					"name":"E3D81_00685 integration host factor subunit beta\tK03530 hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"E3D81_03580 recQ; DNA helicase RecQ\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_07655 RecQ family ATP-dependent DNA helicase\tK03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]"
				},
				{
					"name":"E3D81_03910 dinB; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_10640 dinB; DNA polymerase IV\tK02346 dinB; DNA polymerase IV [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_10665 DNA polymerase III subunit alpha\tK14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]"
				},
				{
					"name":"E3D81_03985 RecX family transcriptional regulator\tK03565 recX; regulatory protein"
				},
				{
					"name":"E3D81_07175 DNA polymerase\/3'-5' exonuclease PolX\tK02347 polX; DNA polymerase (family X)"
				},
				{
					"name":"E3D81_03335 ligase-associated DNA damage response DEXH box helicase\tK03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]"
				},
				{
					"name":"E3D81_02235 nrdE; class 1b ribonucleoside-diphosphate reductase subunit alpha\tK00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_02230 nrdF; class 1b ribonucleoside-diphosphate reductase subunit beta\tK00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]"
				},
				{
					"name":"E3D81_01895 bifunctional oligoribonuclease\/PAP phosphatase NrnA\tK06881 nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]"
				}
				]
			},
			{
				"name":"03029 Mitochondrial biogenesis [BR:sphz03029]",
				"children":[
				{
					"name":"E3D81_12395 infB; translation initiation factor IF-2\tK02519 infB; translation initiation factor IF-2"
				},
				{
					"name":"E3D81_10935 translation initiation factor IF-3\tK02520 infC; translation initiation factor IF-3"
				},
				{
					"name":"E3D81_09855 elongation factor Ts\tK02357 tsf; elongation factor Ts"
				},
				{
					"name":"E3D81_09285 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"E3D81_11805 fusA; elongation factor G\tK02355 fusA; elongation factor G"
				},
				{
					"name":"E3D81_08635 GTPase Era\tK03595 era; GTPase"
				},
				{
					"name":"E3D81_02075 tyrosine--tRNA ligase\tK01866 YARS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"E3D81_03830 leucine--tRNA ligase\tK01869 LARS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"E3D81_07790 aspS; aspartate--tRNA ligase\tK01876 DARS2; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"E3D81_02315 glycine--tRNA ligase\tK01880 GARS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"E3D81_06340 arginine--tRNA ligase\tK01887 RARS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"E3D81_06600 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_15275 single-stranded DNA-binding protein\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"E3D81_07385 bamA; outer membrane protein assembly factor BamA\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_03600 nucleotide exchange factor GrpE\tK03687 GRPE; molecular chaperone GrpE"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"E3D81_15215 co-chaperone GroES\tK04078 groES; chaperonin GroES"
				},
				{
					"name":"E3D81_03595 dnaJ; molecular chaperone DnaJ\tK03686 dnaJ; molecular chaperone DnaJ"
				},
				{
					"name":"E3D81_10860 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_13725 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_07165 2Fe-2S iron-sulfur cluster binding domain-containing protein\tK22071 FDX2; ferredoxin-2, mitochondrial"
				},
				{
					"name":"E3D81_14860 iron-sulfur cluster carrier protein ApbC\tK03593 mrp; ATP-binding protein involved in chromosome partitioning"
				},
				{
					"name":"E3D81_08235 cyoE; protoheme IX farnesyltransferase\tK02257 COX10; heme o synthase [EC:2.5.1.141]"
				},
				{
					"name":"E3D81_08230 heme A synthase\tK02259 COX15; heme a synthase [EC:1.17.99.9]"
				},
				{
					"name":"E3D81_10005 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"E3D81_11210 SCO family protein\tK07152 SCO1; protein SCO1"
				},
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			}
			]
		},
		{
			"name":"09183 Protein families: signaling and cellular processes",
			"children":[
			{
				"name":"02000 Transporters [BR:sphz02000]",
				"children":[
				{
					"name":"E3D81_13165 ABC transporter ATP-binding protein\tK11085 msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:7.5.2.6]"
				},
				{
					"name":"E3D81_06900 ABC transporter ATP-binding protein\tK18889 mdlA; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"E3D81_00865 ABC transporter ATP-binding protein\tK18890 mdlB; ATP-binding cassette, subfamily B, multidrug efflux pump"
				},
				{
					"name":"E3D81_03280 ABC transporter ATP-binding protein\tK06147 ABCB-BAC; ATP-binding cassette, subfamily B, bacterial"
				},
				{
					"name":"E3D81_00070 ABC transporter ATP-binding protein\tK15738 uup; ABC transport system ATP-binding\/permease protein"
				},
				{
					"name":"E3D81_02205 ATP-binding cassette domain-containing protein\tK05776 modF; molybdate transport system ATP-binding protein"
				},
				{
					"name":"E3D81_07875 MCE family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"E3D81_10730 MCE family protein\tK02067 mlaD; phospholipid\/cholesterol\/gamma-HCH transport system substrate-binding protein"
				},
				{
					"name":"E3D81_09635 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"E3D81_10720 ABC transporter permease\tK02066 mlaE; phospholipid\/cholesterol\/gamma-HCH transport system permease protein"
				},
				{
					"name":"E3D81_09640 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"E3D81_10725 ATP-binding cassette domain-containing protein\tK02065 mlaF; phospholipid\/cholesterol\/gamma-HCH transport system ATP-binding protein"
				},
				{
					"name":"E3D81_03660 PstS family phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_11930 phosphate ABC transporter substrate-binding protein\tK02040 pstS; phosphate transport system substrate-binding protein"
				},
				{
					"name":"E3D81_03655 pstC; phosphate ABC transporter permease subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_11935 pstC; phosphate ABC transporter permease subunit PstC\tK02037 pstC; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_03650 ABC transporter permease subunit\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_11940 pstA; phosphate ABC transporter permease PstA\tK02038 pstA; phosphate transport system permease protein"
				},
				{
					"name":"E3D81_03645 phosphate ABC transporter ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"E3D81_11945 pstB; phosphate ABC transporter ATP-binding protein\tK02036 pstB; phosphate transport system ATP-binding protein [EC:7.3.2.1]"
				},
				{
					"name":"E3D81_03365 hemin ABC transporter substrate-binding protein\tK25132 hmuT; heme transport system substrate-binding protein"
				},
				{
					"name":"E3D81_03360 iron ABC transporter permease\tK25133 hmuU; heme transport system permease protein"
				},
				{
					"name":"E3D81_03355 heme ABC transporter ATP-binding protein\tK10834 hmuV; heme transport system ATP-binding protein [EC:7.6.2.5]"
				},
				{
					"name":"E3D81_09795 YjgP\/YjgQ family permease\tK07091 lptF; lipopolysaccharide export system permease protein"
				},
				{
					"name":"E3D81_08465 YjgP\/YjgQ family permease\tK11720 lptG; lipopolysaccharide export system permease protein"
				},
				{
					"name":"E3D81_08610 lptB; LPS export ABC transporter ATP-binding protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"E3D81_10580 ATP-binding cassette domain-containing protein\tK06861 lptB; lipopolysaccharide export system ATP-binding protein [EC:7.5.2.5]"
				},
				{
					"name":"E3D81_16680 ABC transporter permease\tK19341 nosY; Cu-processing system permease protein"
				},
				{
					"name":"E3D81_16685 ABC transporter ATP-binding protein\tK19340 nosF; Cu-processing system ATP-binding protein"
				},
				{
					"name":"E3D81_12640 ABC transporter\tK25151 gldF; gliding motility-associated transport system permease protein"
				},
				{
					"name":"E3D81_12650 ABC transporter\tK25151 gldF; gliding motility-associated transport system permease protein"
				},
				{
					"name":"E3D81_12645 ATP-binding cassette domain-containing protein\tK25152 gldA; gliding motility-associated transport system ATP-binding protein"
				},
				{
					"name":"E3D81_04880 ABC transporter permease\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"E3D81_16490 ABC transporter permease\tK09808 lolC_E_F; lipoprotein-releasing system permease protein"
				},
				{
					"name":"E3D81_02355 ABC transporter ATP-binding protein\tK09810 lolD; lipoprotein-releasing system ATP-binding protein [EC:7.6.2.-]"
				},
				{
					"name":"E3D81_01680 ABC transporter permease\tK02195 ccmC; heme exporter protein C"
				},
				{
					"name":"E3D81_01685 ABC transporter permease\tK02194 ccmB; heme exporter protein B"
				},
				{
					"name":"E3D81_03835 FtsX-like permease family protein\tK09811 ftsX; cell division transport system permease protein"
				},
				{
					"name":"E3D81_03605 ATP-binding cassette domain-containing protein\tK09812 ftsE; cell division transport system ATP-binding protein"
				},
				{
					"name":"E3D81_03395 ABC transporter permease\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"E3D81_03525 ABC transporter permease\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"E3D81_13000 hypothetical protein\tK01992 ABC-2.P; ABC-2 type transport system permease protein"
				},
				{
					"name":"E3D81_02450 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"E3D81_03530 ATP-binding cassette domain-containing protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"E3D81_09125 ABC transporter ATP-binding protein\tK01990 ABC-2.A; ABC-2 type transport system ATP-binding protein"
				},
				{
					"name":"E3D81_09195 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09200 ABC transporter permease\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09205 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09210 ABC transporter permease\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09215 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09220 ABC transporter permease\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09225 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_10805 ABC transporter permease\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_11970 FtsX-like permease family protein\tK02004 ABC.CD.P; putative ABC transport system permease protein"
				},
				{
					"name":"E3D81_09190 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"E3D81_09230 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"E3D81_10810 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"E3D81_11965 ABC transporter ATP-binding protein\tK02003 ABC.CD.A; putative ABC transport system ATP-binding protein"
				},
				{
					"name":"E3D81_00925 sufC; Fe-S cluster assembly ATPase SufC\tK09013 sufC; Fe-S cluster assembly ATP-binding protein"
				},
				{
					"name":"E3D81_04240 bile acid:sodium symporter\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
				},
				{
					"name":"E3D81_07840 MATE family efflux transporter\tK26939 norM; MATE family, multidrug efflux pump"
				},
				{
					"name":"E3D81_01445 gluP; glucose\/galactose MFS transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"E3D81_06085 fucP; L-fucose:H+ symporter permease\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"E3D81_06135 fucP; L-fucose:H+ symporter permease\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"E3D81_07520 MFS transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"E3D81_14450 gluP; glucose\/galactose MFS transporter\tK02429 fucP; MFS transporter, FHS family, fucose-galactose-glucose:H+ symporter family protein"
				},
				{
					"name":"E3D81_10830 MFS transporter\tK11537 xapB; MFS transporter, NHS family, xanthosine permease"
				},
				{
					"name":"E3D81_00640 MFS transporter\tK08191 exuT; MFS transporter, ACS family, aldohexuronate transporter"
				},
				{
					"name":"E3D81_10955 MFS transporter\tK08191 exuT; MFS transporter, ACS family, aldohexuronate transporter"
				},
				{
					"name":"E3D81_09450 MFS transporter\tK08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein"
				},
				{
					"name":"E3D81_07095 Bcr\/CflA family efflux MFS transporter\tK07552 bcr; MFS transporter, DHA1 family, multidrug resistance protein"
				},
				{
					"name":"E3D81_00935 MFS transporter\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				},
				{
					"name":"E3D81_03810 MFS transporter\tK08223 fsr; MFS transporter, FSR family, fosmidomycin resistance protein"
				},
				{
					"name":"E3D81_05550 MFS transporter\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"E3D81_11510 aqpZ; aquaporin Z\tK06188 aqpZ; aquaporin"
				},
				{
					"name":"E3D81_13735 aquaporin family protein\tK02440 glpF; glycerol uptake facilitator"
				},
				{
					"name":"E3D81_12435 ammonium transporter\tK03320 amt; ammonium transporter, Amt family"
				},
				{
					"name":"E3D81_07800 DUF3520 domain-containing protein\tK07114 yfbK; Ca-activated chloride channel homolog"
				},
				{
					"name":"E3D81_07705 mscL; large-conductance mechanosensitive channel protein MscL\tK03282 mscL; large conductance mechanosensitive channel"
				},
				{
					"name":"E3D81_05355 mechanosensitive ion channel\tK03442 mscS; small conductance mechanosensitive channel"
				},
				{
					"name":"E3D81_13730 mechanosensitive ion channel\tK03442 mscS; small conductance mechanosensitive channel"
				},
				{
					"name":"E3D81_07475 mgtE; magnesium transporter\tK06213 mgtE; magnesium transporter"
				},
				{
					"name":"E3D81_01930 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB"
				},
				{
					"name":"E3D81_16335 MotA\/TolQ\/ExbB proton channel family protein\tK03561 exbB; biopolymer transport protein ExbB"
				},
				{
					"name":"E3D81_01925 biopolymer transporter ExbD\tK03559 exbD; biopolymer transport protein ExbD"
				},
				{
					"name":"E3D81_07680 magnesium transporter CorA\tK03284 corA; magnesium transporter"
				},
				{
					"name":"E3D81_06045 crcB; fluoride efflux transporter CrcB\tK06199 crcB; fluoride exporter"
				},
				{
					"name":"E3D81_03300 hypothetical protein\tK08994 yneE; ion channel-forming bestrophin family protein"
				},
				{
					"name":"E3D81_10175 merTP; mercuric transport protein MerTP\tK08363 merT; mercuric ion transport protein"
				},
				{
					"name":"E3D81_03315 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"E3D81_10790 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"E3D81_03925 porin\tK07221 oprO_P; phosphate-selective porin OprO and OprP"
				},
				{
					"name":"E3D81_11560 OmpA family protein\tK03286 TC.OOP; OmpA-OmpF porin, OOP family"
				},
				{
					"name":"E3D81_16470 OmpA family protein\tK03286 TC.OOP; OmpA-OmpF porin, OOP family"
				},
				{
					"name":"E3D81_02345 long-chain fatty acid transporter\tK06076 fadL; long-chain fatty acid transport protein"
				},
				{
					"name":"E3D81_04765 TonB-dependent receptor\tK16092 btuB; vitamin B12 transporter"
				},
				{
					"name":"E3D81_02260 SusC\/RagA family TonB-linked outer membrane protein\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_02515 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_05950 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_06840 SusC\/RagA family TonB-linked outer membrane protein\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_08075 SusC\/RagA family TonB-linked outer membrane protein\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_08315 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_08720 SusC\/RagA family TonB-linked outer membrane protein\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_12070 SusC\/RagA family TonB-linked outer membrane protein\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_13895 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_14460 TonB-dependent receptor\tK21573 susC; TonB-dependent starch-binding outer membrane protein SusC"
				},
				{
					"name":"E3D81_03375 TonB-dependent receptor\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"E3D81_08845 TonB-dependent receptor\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"E3D81_09420 TonB-dependent receptor\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"E3D81_10135 TonB-dependent receptor\tK16089 TC.FEV.OM2; outer membrane receptor for ferrienterochelin and colicins"
				},
				{
					"name":"E3D81_03095 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_04950 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_10345 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_14945 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_16505 TonB-dependent siderophore receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_16655 TonB-dependent receptor\tK02014 TC.FEV.OM; iron complex outermembrane recepter protein"
				},
				{
					"name":"E3D81_10330 TolC family protein\tK15725 czcC; outer membrane protein, heavy metal efflux system"
				},
				{
					"name":"E3D81_13120 TolC family protein\tK15725 czcC; outer membrane protein, heavy metal efflux system"
				},
				{
					"name":"E3D81_10245 TolC family protein\tK07796 cusC; outer membrane protein, copper\/silver efflux system"
				},
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_05070 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12245 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_03290 sugar transporter\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"E3D81_15940 sugar transporter\tK01991 wza; polysaccharide biosynthesis\/export protein"
				},
				{
					"name":"E3D81_07385 bamA; outer membrane protein assembly factor BamA\tK07277 SAM50; outer membrane protein insertion porin family"
				},
				{
					"name":"E3D81_00785 bamD; outer membrane protein assembly factor BamD\tK05807 bamD; outer membrane protein assembly factor BamD"
				},
				{
					"name":"E3D81_08045 MFS transporter\tK16211 malY; maltose\/moltooligosaccharide transporter"
				},
				{
					"name":"E3D81_06975 amino acid permease\tK11734 aroP; aromatic amino acid transport protein AroP"
				},
				{
					"name":"E3D81_06950 zinc\/iron permease\tK16267 zipB; zinc and cadmium transporter"
				},
				{
					"name":"E3D81_03430 ZIP family metal transporter\tK07238 TC.ZIP; zinc transporter, ZIP family"
				},
				{
					"name":"E3D81_10195 CusA\/CzcA family heavy metal efflux RND transporter\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"E3D81_13130 efflux RND transporter permease subunit\tK15726 czcA; heavy metal efflux system protein"
				},
				{
					"name":"E3D81_10240 efflux RND transporter permease subunit\tK07787 cusA; copper\/silver efflux system protein"
				},
				{
					"name":"E3D81_05065 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_06700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_07040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_08700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11175 multidrug efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11355 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11915 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_12240 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_01600 multidrug efflux SMR transporter\tK11741 sugE; quaternary ammonium compound-resistance protein SugE"
				},
				{
					"name":"E3D81_05930 DMT family transporter\tK11939 rhtA; inner membrane transporter RhtA"
				},
				{
					"name":"E3D81_03005 EamA family transporter\tK05786 rarD; chloramphenicol-sensitive protein RarD"
				},
				{
					"name":"E3D81_15435 BCCT family transporter\tK02168 betT; choline\/glycine\/proline betaine transport protein"
				},
				{
					"name":"E3D81_13460 dctA; C4-dicarboxylate transporter DctA\tK11103 dctA; aerobic C4-dicarboxylate transport protein"
				},
				{
					"name":"E3D81_03520 nhaA; Na+\/H+ antiporter NhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family"
				},
				{
					"name":"E3D81_06145 nhaA; Na+\/H+ antiporter NhaA\tK03313 nhaA; Na+:H+ antiporter, NhaA family"
				},
				{
					"name":"E3D81_14430 Na+\/H+ antiporter\tK24163 nhaK; monovalent cation\/hydrogen antiporter"
				},
				{
					"name":"E3D81_04875 cation:proton antiporter\tK26730 napA; Na+:H+ antiporter"
				},
				{
					"name":"E3D81_08625 potassium:proton antiporter\tK07228 khtT; K+:H+ antiporter subunit KhtT"
				},
				{
					"name":"E3D81_08630 cation:proton antiporter\tK26732 khtU; K+:H+ antiporter subunit KhtU"
				},
				{
					"name":"E3D81_15735 ATPase\tK03498 trkH; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"E3D81_15740 TrkA family potassium uptake protein\tK03499 trkA; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"E3D81_16420 TrkA family potassium uptake protein\tK03499 trkA; trk\/ktr system potassium uptake protein"
				},
				{
					"name":"E3D81_12230 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"E3D81_16195 chloride channel protein\tK03281 clcA; chloride channel protein, CIC family"
				},
				{
					"name":"E3D81_11950 SulP family inorganic anion transporter\tK03321 TC.SULP; sulfate permease, SulP family"
				},
				{
					"name":"E3D81_10315 arsB; ACR3 family arsenite efflux transporter\tK03325 ACR3; arsenite transporter"
				},
				{
					"name":"E3D81_08530 putative monovalent cation\/H+ antiporter subunit A\tK05565 mnhA; multicomponent Na+:H+ antiporter subunit A"
				},
				{
					"name":"E3D81_08525 Na+\/H+ antiporter subunit B\tK05566 mnhB; multicomponent Na+:H+ antiporter subunit B"
				},
				{
					"name":"E3D81_08520 Na+\/H+ antiporter subunit C\tK05567 mnhC; multicomponent Na+:H+ antiporter subunit C"
				},
				{
					"name":"E3D81_08515 Na+\/H+ antiporter subunit D\tK05568 mnhD; multicomponent Na+:H+ antiporter subunit D"
				},
				{
					"name":"E3D81_08510 Na+\/H+ antiporter subunit E\tK05569 mnhE; multicomponent Na+:H+ antiporter subunit E"
				},
				{
					"name":"E3D81_08505 cation:proton antiporter\tK05570 mnhF; multicomponent Na+:H+ antiporter subunit F"
				},
				{
					"name":"E3D81_08500 monovalent cation\/H(+) antiporter subunit G\tK05571 mnhG; multicomponent Na+:H+ antiporter subunit G"
				},
				{
					"name":"E3D81_06460 AEC family transporter\tK24180 mleP; malate permease and related proteins"
				},
				{
					"name":"E3D81_02060 potassium transporter Kup\tK03549 kup; KUP system potassium uptake protein"
				},
				{
					"name":"E3D81_07750 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
				},
				{
					"name":"E3D81_02905 hypothetical protein\tK03832 tonB; periplasmic protein TonB"
				},
				{
					"name":"E3D81_09080 hypothetical protein\tK03832 tonB; periplasmic protein TonB"
				},
				{
					"name":"E3D81_16320 energy transducer TonB\tK03832 tonB; periplasmic protein TonB"
				},
				{
					"name":"E3D81_07650 sodium-translocating pyrophosphatase\tK15987 hppA; K(+)-stimulated pyrophosphate-energized sodium pump [EC:7.2.3.1]"
				},
				{
					"name":"E3D81_10200 efflux RND transporter periplasmic adaptor subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"E3D81_13125 efflux RND transporter periplasmic adaptor subunit\tK15727 czcB; membrane fusion protein, heavy metal efflux system"
				},
				{
					"name":"E3D81_10250 efflux RND transporter periplasmic adaptor subunit\tK07798 cusB; membrane fusion protein, copper\/silver efflux system"
				},
				{
					"name":"E3D81_05060 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06705 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_08695 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11180 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11350 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11920 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12235 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_03295 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_04420 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15885 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_15935 polysaccharide biosynthesis tyrosine autokinase\tK16692 etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
				},
				{
					"name":"E3D81_00325 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_00340 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_00370 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_01325 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_01535 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_02135 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_02255 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_02510 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_05100 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_05135 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_05910 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_05945 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_06070 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_06825 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_06845 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_08070 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_08145 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_08320 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_08725 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_10435 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_11735 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12065 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12085 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12470 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12625 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12720 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_12745 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_13225 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_13890 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14060 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14180 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14335 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14375 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14465 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_14870 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_15130 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_15745 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_16370 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_16760 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_16920 RagB\/SusD family nutrient uptake outer membrane protein\tK21572 susD; starch-binding outer membrane protein, SusD\/RagB family"
				},
				{
					"name":"E3D81_08780 nicotinamide riboside transporter PnuC\tK03811 pnuC; nicotinamide mononucleotide transporter"
				},
				{
					"name":"E3D81_13255 nicotinamide riboside transporter PnuC\tK03811 pnuC; nicotinamide mononucleotide transporter"
				},
				{
					"name":"E3D81_06960 ferrous iron transport protein A\tK04758 feoA; ferrous iron transport protein A"
				},
				{
					"name":"E3D81_06965 feoB; ferrous iron transport protein B\tK04759 feoB; ferrous iron transport protein B"
				},
				{
					"name":"E3D81_09505 cytochrome C biogenesis protein\tK02198 ccmF; cytochrome c-type biogenesis protein CcmF"
				},
				{
					"name":"E3D81_09335 MgtC\/SapB family protein\tK07507 mgtC; putative Mg2+ transporter-C (MgtC) family protein"
				}
				]
			},
			{
				"name":"02044 Secretion system [BR:sphz02044]",
				"children":[
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07660 ComEC family competence protein\tK02238 comEC; competence protein ComEC"
				},
				{
					"name":"E3D81_17075 secA; preprotein translocase subunit SecA\tK03070 secA; preprotein translocase subunit SecA [EC:7.4.2.8]"
				},
				{
					"name":"E3D81_06170 protein translocase subunit SecDF\tK12257 secDF; SecD\/SecF fusion protein"
				},
				{
					"name":"E3D81_09295 secE; preprotein translocase subunit SecE\tK03073 secE; preprotein translocase subunit SecE"
				},
				{
					"name":"E3D81_15220 secG; preprotein translocase subunit SecG\tK03075 secG; preprotein translocase subunit SecG"
				},
				{
					"name":"E3D81_02660 secY; preprotein translocase subunit SecY\tK03076 secY; preprotein translocase subunit SecY"
				},
				{
					"name":"E3D81_09015 signal recognition particle protein\tK03106 SRP54; signal recognition particle subunit SRP54 [EC:3.6.5.4]"
				},
				{
					"name":"E3D81_16970 ftsY; signal recognition particle-docking protein FtsY\tK03110 ftsY; fused signal recognition particle receptor"
				},
				{
					"name":"E3D81_06880 yajC; preprotein translocase subunit YajC\tK03210 yajC; preprotein translocase subunit YajC"
				},
				{
					"name":"E3D81_10005 yidC; membrane protein insertase YidC\tK03217 yidC; YidC\/Oxa1 family membrane protein insertase"
				},
				{
					"name":"E3D81_07835 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09890 twin-arginine translocase TatA\/TatE family subunit\tK03116 tatA; sec-independent protein translocase protein TatA"
				},
				{
					"name":"E3D81_09140 tatC; twin-arginine translocase subunit TatC\tK03118 tatC; sec-independent protein translocase protein TatC"
				}
				]
			},
			{
				"name":"02042 Bacterial toxins [BR:sphz02042]",
				"children":[
				{
					"name":"E3D81_03315 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"E3D81_10790 HlyC\/CorC family transporter\tK03699 tlyC; magnesium and cobalt exporter, CNNM family"
				},
				{
					"name":"E3D81_13565 phospholipase C, phosphocholine-specific\tK01114 plc; phospholipase C [EC:3.1.4.3]"
				}
				]
			},
			{
				"name":"02022 Two-component system [BR:sphz02022]",
				"children":[
				{
					"name":"E3D81_02820 GHKL domain-containing protein\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_10755 HAMP domain-containing histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_16455 sensor histidine kinase\tK07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_10760 response regulator transcription factor\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"E3D81_11585 response regulator transcription factor\tK07658 phoB1; two-component system, OmpR family, alkaline phosphatase synthesis response regulator PhoP"
				},
				{
					"name":"E3D81_13110 response regulator transcription factor\tK02483 K02483; two-component system, OmpR family, response regulator"
				},
				{
					"name":"E3D81_15535 response regulator\tK02483 K02483; two-component system, OmpR family, response regulator"
				},
				{
					"name":"E3D81_07710 response regulator transcription factor\tK07689 uvrY; two-component system, NarL family, invasion response regulator UvrY"
				},
				{
					"name":"E3D81_12530 response regulator transcription factor\tK07696 nreC; two-component system, NarL family, response regulator NreC"
				},
				{
					"name":"E3D81_00660 response regulator transcription factor\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"E3D81_03635 response regulator transcription factor\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"E3D81_08935 response regulator transcription factor\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"E3D81_11070 response regulator\tK02477 K02477; two-component system, LytTR family, response regulator"
				},
				{
					"name":"E3D81_09245 sigma-54-dependent Fis family transcriptional regulator\tK07713 zraR; two-component system, NtrC family, response regulator HydG"
				},
				{
					"name":"E3D81_15830 histidine kinase\tK02482 flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]"
				},
				{
					"name":"E3D81_02855 chemotaxis protein CheB\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				},
				{
					"name":"E3D81_04685 GHKL domain-containing protein\tK11354 cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
				}
				]
			},
			{
				"name":"02035 Bacterial motility proteins [BR:sphz02035]",
				"children":[
				{
					"name":"E3D81_02850 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"E3D81_15530 protein-glutamate O-methyltransferase CheR\tK00575 cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]"
				},
				{
					"name":"E3D81_02855 chemotaxis protein CheB\tK03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase\/glutaminase [EC:3.1.1.61 3.5.1.44]"
				}
				]
			},
			{
				"name":"03037 Cilium and associated proteins"
			},
			{
				"name":"04812 Cytoskeleton proteins [BR:sphz04812]",
				"children":[
				{
					"name":"E3D81_07185 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"E3D81_07725 ftsZ; cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"E3D81_07730 ftsA; cell division protein FtsA\tK03590 ftsA; cell division protein FtsA"
				},
				{
					"name":"E3D81_01395 ParA family protein\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"E3D81_05200 ParA family protein\tK03496 parA; chromosome partitioning protein"
				},
				{
					"name":"E3D81_01400 ParB\/RepB\/Spo0J family partition protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				}
				]
			},
			{
				"name":"04147 Exosome [BR:sphz04147]",
				"children":[
				{
					"name":"E3D81_13785 htpG; molecular chaperone HtpG\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"E3D81_11120 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
				},
				{
					"name":"E3D81_06180 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_06735 gap; type I glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_15360 glyceraldehyde-3-phosphate dehydrogenase\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"E3D81_07490 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
				},
				{
					"name":"E3D81_02810 pyk; pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"E3D81_00985 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				},
				{
					"name":"E3D81_00265 peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
				},
				{
					"name":"E3D81_15210 groL; chaperonin GroEL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
				},
				{
					"name":"E3D81_14745 dnaK; molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
				},
				{
					"name":"E3D81_16200 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
				},
				{
					"name":"E3D81_05385 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_11090 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_14395 SMP-30\/gluconolactonase\/LRE family protein\tK01053 gnl; gluconolactonase [EC:3.1.1.17]"
				},
				{
					"name":"E3D81_06150 guaB; IMP dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
				},
				{
					"name":"E3D81_09285 tuf; elongation factor Tu\tK02358 tuf; elongation factor Tu"
				},
				{
					"name":"E3D81_10770 HIT family protein\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"E3D81_04240 bile acid:sodium symporter\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
				},
				{
					"name":"E3D81_11455 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_12280 long-chain fatty acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
				},
				{
					"name":"E3D81_02105 acetyl-CoA C-acyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
				},
				{
					"name":"E3D81_08765 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
				},
				{
					"name":"E3D81_06200 adenylate kinase\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
				},
				{
					"name":"E3D81_12960 adenine phosphoribosyltransferase\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
				},
				{
					"name":"E3D81_02940 argH; argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
				},
				{
					"name":"E3D81_02410 argG; argininosuccinate synthase\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
				},
				{
					"name":"E3D81_11270 cystathionine gamma-synthase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
				},
				{
					"name":"E3D81_12190 class 1 fructose-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
				},
				{
					"name":"E3D81_02290 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_06670 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_08115 alpha-L-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_12035 alpha-1,3\/4-fucosidase\tK01206 FUCA; alpha-L-fucosidase [EC:3.2.1.51]"
				},
				{
					"name":"E3D81_15460 galK; galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
				},
				{
					"name":"E3D81_12895 glgB; 1,4-alpha-glucan branching protein GlgB\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
				},
				{
					"name":"E3D81_13740 glpK; glycerol kinase GlpK\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
				},
				{
					"name":"E3D81_03080 glutamine synthetase type III\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
				},
				{
					"name":"E3D81_02980 hemB; porphobilinogen synthase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
				},
				{
					"name":"E3D81_12305 hppD; 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
				},
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"E3D81_03455 3-phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_08560 phosphoglycerate dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_10975 hydroxyacid dehydrogenase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_14990 phosphoserine phosphatase\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
				},
				{
					"name":"E3D81_11035 purH; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
				},
				{
					"name":"E3D81_02870 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_02885 lpdA; dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
				},
				{
					"name":"E3D81_10840 electron transfer flavoprotein subunit alpha\/FixB family protein\tK03522 fixB; electron transfer flavoprotein alpha subunit"
				},
				{
					"name":"E3D81_17040 Glu\/Leu\/Phe\/Val dehydrogenase\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
				},
				{
					"name":"E3D81_04915 triose-phosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
				},
				{
					"name":"E3D81_06580 lipocalin\tK03098 APOD; apolipoprotein D and lipocalin family protein"
				},
				{
					"name":"E3D81_14295 hypothetical protein\tK03098 APOD; apolipoprotein D and lipocalin family protein"
				}
				]
			},
			{
				"name":"02048 Prokaryotic defense system [BR:sphz02048]",
				"children":[
				{
					"name":"E3D81_14005 type I restriction endonuclease subunit R\tK01153 hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]"
				},
				{
					"name":"E3D81_13990 restriction endonuclease subunit S\tK01154 hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]"
				},
				{
					"name":"E3D81_13985 SAM-dependent DNA methyltransferase\tK03427 hsdM; type I restriction enzyme M protein [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_00110 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_05320 DNA adenine methylase\tK06223 dam; DNA adenine methylase [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_00125 site-specific DNA-methyltransferase\tK00571 E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]"
				},
				{
					"name":"E3D81_05185 hypothetical protein\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"E3D81_11545 type II toxin-antitoxin system PemK\/MazF family toxin\tK07171 mazF; mRNA interferase MazF [EC:3.1.-.-]"
				},
				{
					"name":"E3D81_12155 type II toxin-antitoxin system HipA family toxin\tK07154 hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
				},
				{
					"name":"E3D81_04165 plasmid maintenance system antidote protein\tK21498 higA-1; antitoxin HigA-1"
				},
				{
					"name":"E3D81_07725 ftsZ; cell division protein FtsZ\tK03531 ftsZ; cell division protein FtsZ"
				},
				{
					"name":"E3D81_07185 rod shape-determining protein\tK03569 mreB; rod shape-determining protein MreB and related proteins"
				},
				{
					"name":"E3D81_10630 DNA gyrase\/topoisomerase IV subunit A\tK02621 parC; topoisomerase IV subunit A [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_09655 type IIA DNA topoisomerase subunit B\tK02622 parE; topoisomerase IV subunit B [EC:5.6.2.2]"
				},
				{
					"name":"E3D81_01465 glutamate--tRNA ligase\tK01885 EARS; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"E3D81_10860 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"E3D81_13725 cysteine desulfurase\tK04487 iscS; cysteine desulfurase [EC:2.8.1.7]"
				}
				]
			},
			{
				"name":"04030 G protein-coupled receptors"
			},
			{
				"name":"04050 Cytokine receptors"
			},
			{
				"name":"04054 Pattern recognition receptors"
			},
			{
				"name":"03310 Nuclear receptors"
			},
			{
				"name":"04040 Ion channels"
			},
			{
				"name":"04031 GTP-binding proteins"
			},
			{
				"name":"04052 Cytokines and neuropeptides"
			},
			{
				"name":"04515 Cell adhesion molecules"
			},
			{
				"name":"04090 CD molecules [BR:sphz04090]",
				"children":[
				{
					"name":"E3D81_05385 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				},
				{
					"name":"E3D81_11090 S9 family peptidase\tK01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]"
				}
				]
			},
			{
				"name":"01504 Antimicrobial resistance genes [BR:sphz01504]",
				"children":[
				{
					"name":"E3D81_11640 aminoglycoside 6-adenylyltransferase AadS\tK05593 aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]"
				},
				{
					"name":"E3D81_11720 aminoglycoside adenylyltransferase\tK05593 aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]"
				},
				{
					"name":"E3D81_09450 MFS transporter\tK08151 tetA; MFS transporter, DHA1 family, tetracycline resistance protein"
				},
				{
					"name":"E3D81_00935 MFS transporter\tK08217 mef; MFS transporter, DHA3 family, macrolide efflux protein"
				},
				{
					"name":"E3D81_12730 macrolide 2'-phosphotransferase\tK06979 mph; macrolide phosphotransferase"
				},
				{
					"name":"E3D81_15800 chloramphenicol acetyltransferase\tK19271 catA; chloramphenicol O-acetyltransferase type A [EC:2.3.1.28]"
				},
				{
					"name":"E3D81_00730 hypothetical protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_02040 M56 family peptidase\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_09070 TonB family protein\tK02172 blaR1; bla regulator protein blaR1"
				},
				{
					"name":"E3D81_00735 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_02045 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03715 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_03730 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_09065 BlaI\/MecI\/CopY family transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"E3D81_14365 bla; class A beta-lactamase\tK17836 penP; beta-lactamase class A [EC:3.5.2.6]"
				},
				{
					"name":"E3D81_07295 peptidase M15\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
				},
				{
					"name":"E3D81_12325 lysylphosphatidylglycerol synthetase family protein\tK14205 mprF; phosphatidylglycerol lysyltransferase [EC:2.3.2.3]"
				},
				{
					"name":"E3D81_05060 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06705 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_07045 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_08695 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11180 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11350 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_11920 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12235 efflux RND transporter periplasmic adaptor subunit\tK03585 acrA; membrane fusion protein, multidrug efflux system"
				},
				{
					"name":"E3D81_05065 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_06700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_07040 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_08700 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11175 multidrug efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11355 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_11915 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_12240 efflux RND transporter permease subunit\tK18138 acrB; multidrug efflux pump"
				},
				{
					"name":"E3D81_05070 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_12245 efflux transporter outer membrane subunit\tK18139 oprM; outer membrane protein, multidrug efflux system"
				},
				{
					"name":"E3D81_06710 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_07050 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_08705 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_09240 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11185 TolC family protein\tK12340 tolC; outer membrane protein"
				},
				{
					"name":"E3D81_11910 TolC family protein\tK12340 tolC; outer membrane protein"
				}
				]
			},
			{
				"name":"00535 Proteoglycans"
			},
			{
				"name":"00536 Glycosaminoglycan binding proteins"
			},
			{
				"name":"00537 Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:sphz00537]",
				"children":[
				{
					"name":"E3D81_06595 alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
				},
				{
					"name":"E3D81_00985 membrane dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
				}
				]
			},
			{
				"name":"04091 Lectins"
			},
			{
				"name":"04990 Domain-containing proteins not elsewhere classified"
			}
			]
		},
		{
			"name":"09185 Viral protein families",
			"children":[
			{
				"name":"03200 Viral proteins"
			},
			{
				"name":"03210 Viral fusion proteins"
			}
			]
		},
		{
			"name":"09184 RNA family",
			"children":[
			{
				"name":"03100 Non-coding RNAs [BR:sphz03100]",
				"children":[
				{
					"name":"E3D81_00750 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_06915 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_11375 tRNA-Ala\tK14218 tRNA-Ala; tRNA Ala"
				},
				{
					"name":"E3D81_00280 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_05005 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_06205 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_06220 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_13620 tRNA-Arg\tK14219 tRNA-Arg; tRNA Arg"
				},
				{
					"name":"E3D81_07465 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"E3D81_07470 tRNA-Asn\tK14220 tRNA-Asn; tRNA Asn"
				},
				{
					"name":"E3D81_01580 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_01585 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_01590 tRNA-Asp\tK14221 tRNA-Asp; tRNA Asp"
				},
				{
					"name":"E3D81_11785 tRNA-Cys\tK14222 tRNA-Cys; tRNA Cys"
				},
				{
					"name":"E3D81_01965 tRNA-Gln\tK14223 tRNA-Gln; tRNA Gln"
				},
				{
					"name":"E3D81_15095 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"E3D81_16855 tRNA-Glu\tK14224 tRNA-Glu; tRNA Glu"
				},
				{
					"name":"E3D81_00940 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_03990 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_04790 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_09275 tRNA-Gly\tK14225 tRNA-Gly; tRNA Gly"
				},
				{
					"name":"E3D81_13790 tRNA-His\tK14226 tRNA-His; tRNA His"
				},
				{
					"name":"E3D81_00745 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"E3D81_11370 tRNA-Ile\tK14227 tRNA-Ile; tRNA Ile"
				},
				{
					"name":"E3D81_03995 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_04795 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_05880 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_07410 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_07910 tRNA-Leu\tK14228 tRNA-Leu; tRNA Leu"
				},
				{
					"name":"E3D81_00390 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_04305 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_12810 tRNA-Lys\tK14229 tRNA-Lys; tRNA Lys"
				},
				{
					"name":"E3D81_05020 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08640 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_08645 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_09805 tRNA-Met\tK14230 tRNA-Met; tRNA Met"
				},
				{
					"name":"E3D81_06745 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"E3D81_06770 tRNA-Phe\tK14231 tRNA-Phe; tRNA Phe"
				},
				{
					"name":"E3D81_10025 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"E3D81_11630 tRNA-Pro\tK14232 tRNA-Pro; tRNA Pro"
				},
				{
					"name":"E3D81_04170 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_04580 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_05715 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_13615 tRNA-Ser\tK14233 tRNA-Ser; tRNA Ser"
				},
				{
					"name":"E3D81_09265 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"E3D81_09280 tRNA-Thr\tK14234 tRNA-Thr; tRNA Thr"
				},
				{
					"name":"E3D81_09290 tRNA-Trp\tK14235 tRNA-Trp; tRNA Trp"
				},
				{
					"name":"E3D81_09270 tRNA-Tyr\tK14236 tRNA-Tyr; tRNA Tyr"
				},
				{
					"name":"E3D81_01370 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"E3D81_01375 tRNA-Val\tK14237 tRNA-Val; tRNA Val"
				},
				{
					"name":"E3D81_00740 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_11365 16S ribosomal RNA\tK01977 16SrRNA; 16S ribosomal RNA"
				},
				{
					"name":"E3D81_00755 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_11380 23S ribosomal RNA\tK01980 23SrRNA; 23S ribosomal RNA"
				},
				{
					"name":"E3D81_00760 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_03070 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_08105 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_11385 rrf; 5S ribosomal RNA\tK01985 5SrRNA; 5S ribosomal RNA"
				},
				{
					"name":"E3D81_06305 rnpB; RNase P RNA component class A\tK01978 rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"E3D81_12160 ssrA; transfer-messenger RNA\tK15035 ssrA; transfer-messenger RNA"
				},
				{
					"name":"E3D81_08445 ffs; signal recognition particle sRNA small type\tK01983 ffs; signal recognition particle 4.5S RNA"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"09190 Not Included in Pathway or Brite",
		"children":[
		{
			"name":"09191 Unclassified: metabolism",
			"children":[
			{
				"name":"99980 Enzymes with EC numbers",
				"children":[
				{
					"name":"E3D81_06430 GMC family oxidoreductase\tK26059 gtd1; glucoside 3-dehydrogenase (cytochrome c) catalytic subunit [EC:1.1.2.11]"
				},
				{
					"name":"E3D81_13355 PQQ-dependent sugar dehydrogenase\tK21430 yliI; aldose sugar dehydrogenase [EC:1.1.5.-]"
				},
				{
					"name":"E3D81_00565 flavodoxin family protein\tK03923 mdaB; NADPH dehydrogenase (quinone) [EC:1.6.5.10]"
				},
				{
					"name":"E3D81_00465 FMN-dependent NADH-azoreductase\tK01118 acpD; FMN-dependent NADH-azoreductase [EC:1.7.1.17]"
				},
				{
					"name":"E3D81_07440 ypdA; YpdA family putative bacillithiol disulfide reductase\tK26960 bdr; bacillithiol disulfide reductase [EC:1.8.1.-]"
				},
				{
					"name":"E3D81_10600 msrA; peptide-methionine (S)-S-oxide reductase MsrA\tK07304 msrA; peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11]"
				},
				{
					"name":"E3D81_12600 peptide-methionine (S)-S-oxide reductase\tK12267 msrAB; peptide methionine sulfoxide reductase msrA\/msrB [EC:1.8.4.11 1.8.4.12]"
				},
				{
					"name":"E3D81_01005 cytochrome-c peroxidase\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]"
				},
				{
					"name":"E3D81_13055 c-type cytochrome\tK00428 E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]"
				},
				{
					"name":"E3D81_02320 thioredoxin-dependent thiol peroxidase\tK03564 BCP; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"E3D81_02340 thiol peroxidase\tK11065 tpx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"E3D81_01545 peroxiredoxin\tK24158 prx; thioredoxin-dependent peroxiredoxin [EC:1.11.1.24]"
				},
				{
					"name":"E3D81_05445 pirin family protein\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]"
				},
				{
					"name":"E3D81_06610 pirin family protein\tK06911 PIR; quercetin 2,3-dioxygenase [EC:1.13.11.24]"
				},
				{
					"name":"E3D81_09710 fatty acid hydroxylase\tK19706 FAH; dihydroceramide fatty acyl 2-hydroxylase [EC:1.14.18.7]"
				},
				{
					"name":"E3D81_09100 ferritin\tK02217 ftnA; ferritin [EC:1.16.3.2]"
				},
				{
					"name":"E3D81_13425 ferritin\tK02217 ftnA; ferritin [EC:1.16.3.2]"
				},
				{
					"name":"E3D81_05635 protein-tyrosine-phosphatase\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]"
				},
				{
					"name":"E3D81_10310 protein-tyrosine-phosphatase\tK03741 arsC; arsenate reductase (thioredoxin) [EC:1.20.4.4]"
				},
				{
					"name":"E3D81_16640 anaerobic ribonucleoside-triphosphate reductase activating protein\tK04069 pflA; pyruvate formate lyase activating enzyme [EC:1.97.1.4]"
				},
				{
					"name":"E3D81_01875 protein-L-isoaspartate(D-aspartate) O-methyltransferase\tK00573 E2.1.1.77; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]"
				},
				{
					"name":"E3D81_04850 methyltransferase domain-containing protein\tK00598 tam; trans-aconitate 2-methyltransferase [EC:2.1.1.144]"
				},
				{
					"name":"E3D81_02610 acetylornithine carbamoyltransferase\tK13043 argF; N-succinyl-L-ornithine transcarbamylase [EC:2.1.3.11]"
				},
				{
					"name":"E3D81_06245 sugar O-acetyltransferase\tK00661 maa; maltose O-acetyltransferase [EC:2.3.1.79]"
				},
				{
					"name":"E3D81_10865 lnt; apolipoprotein N-acyltransferase\tK03820 lnt; apolipoprotein N-acyltransferase [EC:2.3.1.269]"
				},
				{
					"name":"E3D81_04105 GNAT family N-acetyltransferase\tK03826 yiaB_C; [protein]-L-lysine N-acetyltransferase [EC:2.3.1.338]"
				},
				{
					"name":"E3D81_15895 glutaminyl-peptide cyclotransferase\tK22757 QCT; glutaminyl-peptide cyclotransferase [EC:2.3.2.5]"
				},
				{
					"name":"E3D81_02950 leucyl\/phenylalanyl-tRNA--protein transferase\tK00684 aat; leucyl\/phenylalanyl-tRNA---protein transferase [EC:2.3.2.6]"
				},
				{
					"name":"E3D81_05360 ggpS; glucosylglycerol-phosphate synthase\tK03692 E2.4.1.213; glucosylglycerol-phosphate synthase [EC:2.4.1.213]"
				},
				{
					"name":"E3D81_09055 bshA; N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA\tK00754 bshA; L-malate glycosyltransferase [EC:2.4.1.-]"
				},
				{
					"name":"E3D81_03045 deoxyhypusine synthase\tK00809 DHPS; deoxyhypusine synthase [EC:2.5.1.46]"
				},
				{
					"name":"E3D81_07090 lgt; prolipoprotein diacylglyceryl transferase\tK13292 lgt; phosphatidylglycerol---prolipoprotein diacylglyceryl transferase [EC:2.5.1.145]"
				},
				{
					"name":"E3D81_06445 FAD:protein FMN transferase\tK03734 apbE; FAD:protein FMN transferase [EC:2.7.1.180]"
				},
				{
					"name":"E3D81_01425 TIGR00159 family protein\tK18672 dacA; diadenylate cyclase [EC:2.7.7.85]"
				},
				{
					"name":"E3D81_15970 sugar transferase\tK15915 pglC; undecaprenyl phosphate N,N'-diacetylbacillosamine 1-phosphate transferase [EC:2.7.8.36]"
				},
				{
					"name":"E3D81_00285 sialate O-acetylesterase\tK05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53]"
				},
				{
					"name":"E3D81_09375 sialate O-acetylesterase\tK05970 SIAE; sialate O-acetylesterase [EC:3.1.1.53]"
				},
				{
					"name":"E3D81_07590 acyl-CoA thioesterase\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"E3D81_10880 thioesterase\tK07107 ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]"
				},
				{
					"name":"E3D81_06785 tyrosine-protein phosphatase\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"E3D81_16095 protein tyrosine phosphatase\tK01104 E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]"
				},
				{
					"name":"E3D81_07355 histidinol-phosphatase\tK07053 E3.1.3.97; 3',5'-nucleoside bisphosphate phosphatase [EC:3.1.3.97]"
				},
				{
					"name":"E3D81_09545 phosphohistidine phosphatase\tK08296 sixA; phosphohistidine phosphatase [EC:3.1.3.-]"
				},
				{
					"name":"E3D81_05720 HDIG domain-containing protein\tK07037 pgpH; cyclic-di-AMP phosphodiesterase PgpH [EC:3.1.4.-]"
				},
				{
					"name":"E3D81_01905 TatD family deoxyribonuclease\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"E3D81_13695 TatD family deoxyribonuclease\tK03424 tatD; TatD DNase family protein [EC:3.1.21.-]"
				},
				{
					"name":"E3D81_13590 nuclease\tK01174 nuc; micrococcal nuclease [EC:3.1.31.1]"
				},
				{
					"name":"E3D81_08060 alpha-amylase\tK21575 susA; neopullulanase [EC:3.2.1.135]"
				},
				{
					"name":"E3D81_00620 glucuronyl hydrolase\tK18581 ugl; unsaturated chondroitin disaccharide hydrolase [EC:3.2.1.180]"
				},
				{
					"name":"E3D81_05755 DUF5110 domain-containing protein\tK25767 nag31; exo-acting protein-alpha-N-acetylgalactosaminidase [EC:3.2.1.217]"
				},
				{
					"name":"E3D81_09730 DUF1080 domain-containing protein\tK26288 E3.2.1.218; alpha-3'-ketoglucosidase [EC:3.2.1.218]"
				},
				{
					"name":"E3D81_06100 DUF2961 domain-containing protein\tK27494 exoMA1; D-arabinan exo alpha-(1,3)\/(1,5)-arabinofuranosidase (non-reducing end) [EC:3.2.1.225]"
				},
				{
					"name":"E3D81_00720 peptide deformylase\tK01462 PDF; peptide deformylase [EC:3.5.1.88]"
				},
				{
					"name":"E3D81_12950 polysaccharide deacetylase family protein\tK22278 pgdA; peptidoglycan-N-acetylglucosamine deacetylase [EC:3.5.1.104]"
				},
				{
					"name":"E3D81_03865 bshB1; bacillithiol biosynthesis deacetylase BshB1\tK01463 bshB1; N-acetylglucosamine malate deacetylase 1 [EC:3.5.1.-]"
				},
				{
					"name":"E3D81_01280 RidA family protein\tK09022 ridA; 2-iminobutanoate\/2-iminopropanoate deaminase [EC:3.5.99.10]"
				},
				{
					"name":"E3D81_06405 NAD(P)H-hydrate dehydratase\tK23997 nnr; ADP-dependent NAD(P)H-hydrate dehydratase \/ NAD(P)H-hydrate epimerase [EC:4.2.1.136 5.1.99.6]"
				},
				{
					"name":"E3D81_04905 peptidoglycan synthetase\tK02558 mpl; UDP-N-acetylmuramate: L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [EC:6.3.2.45]"
				},
				{
					"name":"E3D81_10355 copper-translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]"
				},
				{
					"name":"E3D81_10380 heavy metal translocating P-type ATPase\tK01533 copB; P-type Cu2+ transporter [EC:7.2.2.9]"
				},
				{
					"name":"E3D81_13580 cation-translocating P-type ATPase\tK01537 ATP2C; P-type Ca2+ transporter type 2C [EC:7.2.2.10]"
				},
				{
					"name":"E3D81_04640 cadA; cadmium-translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				},
				{
					"name":"E3D81_10215 cadA; cadmium-translocating P-type ATPase\tK01534 zntA; Zn2+\/Cd2+-exporting ATPase [EC:7.2.2.12 7.2.2.21]"
				}
				]
			},
			{
				"name":"99981 Carbohydrate metabolism",
				"children":[
				{
					"name":"E3D81_05545 (Fe-S)-binding protein\tK18928 lldE; L-lactate dehydrogenase complex protein LldE"
				},
				{
					"name":"E3D81_07795 iron-sulfur cluster-binding protein\tK18929 lldF; L-lactate dehydrogenase complex protein LldF"
				},
				{
					"name":"E3D81_01060 hypothetical protein\tK00782 lldG; L-lactate dehydrogenase complex protein LldG"
				},
				{
					"name":"E3D81_16960 bshC; bacillithiol biosynthesis cysteine-adding enzyme BshC\tK22136 bshC; bacillithiol synthase"
				},
				{
					"name":"E3D81_06420 gluconate 2-dehydrogenase subunit 3 family protein\tK26060 gtd2; glucoside 3-dehydrogenase (cytochrome c) hitch-hiker subunit"
				}
				]
			},
			{
				"name":"99982 Energy metabolism",
				"children":[
				{
					"name":"E3D81_10845 electron transfer flavoprotein beta subunit\/FixA family protein\tK03521 fixA; electron transfer flavoprotein beta subunit"
				}
				]
			},
			{
				"name":"99983 Lipid metabolism"
			},
			{
				"name":"99984 Nucleotide metabolism",
				"children":[
				{
					"name":"E3D81_02240 nrdI; class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI\tK03647 nrdI; protein involved in ribonucleotide reduction"
				}
				]
			},
			{
				"name":"99985 Amino acid metabolism",
				"children":[
				{
					"name":"E3D81_13300 YggS family pyridoxal phosphate-dependent enzyme\tK06997 yggS; PLP dependent protein"
				}
				]
			},
			{
				"name":"99986 Glycan metabolism",
				"children":[
				{
					"name":"E3D81_02525 flippase-like domain-containing protein\tK07027 K07027; glycosyltransferase 2 family protein"
				}
				]
			},
			{
				"name":"99987 Cofactor metabolism",
				"children":[
				{
					"name":"E3D81_03145 AarF\/ABC1\/UbiB kinase family protein\tK03688 ubiB; ubiquinone biosynthesis protein"
				}
				]
			},
			{
				"name":"99988 Secondary metabolism",
				"children":[
				{
					"name":"E3D81_16800 hypothetical protein\tK03932 lpqC; polyhydroxybutyrate depolymerase"
				},
				{
					"name":"E3D81_01390 NADPH-dependent oxidoreductase\tK19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)"
				},
				{
					"name":"E3D81_03330 NAD(P)H-dependent oxidoreductase\tK19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)"
				},
				{
					"name":"E3D81_13570 NAD(P)H-dependent oxidoreductase\tK19784 chrR; chromate reductase, NAD(P)H dehydrogenase (quinone)"
				}
				]
			},
			{
				"name":"99999 Others",
				"children":[
				{
					"name":"E3D81_00505 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"E3D81_06665 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"E3D81_08270 DoxX family protein\tK15977 K15977; putative oxidoreductase"
				},
				{
					"name":"E3D81_08760 BrxA\/BrxB family bacilliredoxin\tK26958 brxA_B; bacilliredoxin"
				}
				]
			}
			]
		},
		{
			"name":"09192 Unclassified: genetic information processing",
			"children":[
			{
				"name":"99973 Transcription",
				"children":[
				{
					"name":"E3D81_05410 cold-shock protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"E3D81_17000 cold shock domain-containing protein\tK03704 cspA; cold shock protein"
				},
				{
					"name":"E3D81_07830 RNA-binding transcriptional accessory protein\tK06959 tex; protein Tex"
				}
				]
			},
			{
				"name":"99974 Translation",
				"children":[
				{
					"name":"E3D81_06795 exonuclease\tK07577 K07577; putative mRNA 3-end processing factor"
				},
				{
					"name":"E3D81_14305 ligase-associated DNA damage response exonuclease\tK07577 K07577; putative mRNA 3-end processing factor"
				}
				]
			},
			{
				"name":"99975 Protein processing",
				"children":[
				{
					"name":"E3D81_09720 ATP-dependent Clp protease adaptor ClpS\tK06891 clpS; ATP-dependent Clp protease adaptor protein ClpS"
				},
				{
					"name":"E3D81_07915 trigger factor\tK03545 tig; trigger factor"
				},
				{
					"name":"E3D81_01835 smpB; SsrA-binding protein SmpB\tK03664 smpB; SsrA-binding protein"
				},
				{
					"name":"E3D81_02385 OsmC family peroxiredoxin\tK07397 yhfA; putative redox protein"
				},
				{
					"name":"E3D81_04185 OsmC family peroxiredoxin\tK07397 yhfA; putative redox protein"
				},
				{
					"name":"E3D81_11245 nodulation protein NfeD\tK07403 nfeD; membrane-bound serine protease (ClpP class)"
				}
				]
			},
			{
				"name":"99976 Replication and repair",
				"children":[
				{
					"name":"E3D81_14145 hypothetical protein\tK07454 K07454; putative restriction endonuclease"
				},
				{
					"name":"E3D81_00415 DNA repair protein\tK03630 radC; DNA repair protein RadC"
				},
				{
					"name":"E3D81_06615 radC; DNA repair protein RadC\tK03630 radC; DNA repair protein RadC"
				},
				{
					"name":"E3D81_14975 rmuC; DNA recombination protein RmuC\tK09760 rmuC; DNA recombination protein RmuC"
				},
				{
					"name":"E3D81_13610 DUF2813 domain-containing protein\tK07459 ybjD; putative ATP-dependent endonuclease of the OLD family"
				},
				{
					"name":"E3D81_15900 hypothetical protein\tK07460 yraN; putative endonuclease"
				},
				{
					"name":"E3D81_08430 dprA; DNA-protecting protein DprA\tK04096 smf; DNA processing protein"
				},
				{
					"name":"E3D81_16110 replication-associated recombination protein A\tK07478 ycaJ; putative ATPase"
				},
				{
					"name":"E3D81_04000 DDE transposase\tK07485 K07485; transposase"
				},
				{
					"name":"E3D81_06750 DDE transposase\tK07485 K07485; transposase"
				},
				{
					"name":"E3D81_08655 DDE transposase\tK07485 K07485; transposase"
				},
				{
					"name":"E3D81_00595 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_00700 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_01380 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_01570 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_01805 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_02080 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_03075 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_03470 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_04845 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_05615 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_07290 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_07485 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_07845 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_07880 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_08110 hypothetical protein\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_09000 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_11130 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_11195 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_11200 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_11875 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_14500 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_14565 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_14960 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_15365 IS110 family transposase\tK07486 K07486; transposase"
				},
				{
					"name":"E3D81_01235 IS3 family transposase\tK07497 K07497; putative transposase"
				}
				]
			},
			{
				"name":"99979 Viral proteins"
			},
			{
				"name":"99998 Others",
				"children":[
				{
					"name":"E3D81_07535 YbaB\/EbfC family nucleoid-associated protein\tK09747 ebfC; nucleoid-associated protein EbfC"
				},
				{
					"name":"E3D81_07000 deoxyribodipyrimidine photolyase\tK25656 cry; cryptochrome"
				}
				]
			}
			]
		},
		{
			"name":"09193 Unclassified: signaling and cellular processes",
			"children":[
			{
				"name":"99977 Transport",
				"children":[
				{
					"name":"E3D81_02065 amino acid permease\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"E3D81_11535 amino acid permease\tK03294 TC.APA; basic amino acid\/polyamine antiporter, APA family"
				},
				{
					"name":"E3D81_05525 MFS transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family"
				},
				{
					"name":"E3D81_05530 MFS transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family"
				},
				{
					"name":"E3D81_05535 MFS transporter\tK03305 TC.POT; proton-dependent oligopeptide transporter, POT family"
				},
				{
					"name":"E3D81_16465 inorganic phosphate transporter\tK03306 TC.PIT; inorganic phosphate transporter, PiT family"
				},
				{
					"name":"E3D81_08090 putP; sodium\/proline symporter PutP\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"E3D81_15450 sodium transporter\tK03307 TC.SSS; solute:Na+ symporter, SSS family"
				},
				{
					"name":"E3D81_13020 alanine:cation symporter family protein\tK03310 TC.AGCS; alanine or glycine:cation symporter, AGCS family"
				},
				{
					"name":"E3D81_08280 brnQ; branched-chain amino acid transport system II carrier protein\tK03311 TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family"
				}
				]
			},
			{
				"name":"99978 Cell growth",
				"children":[
				{
					"name":"E3D81_02020 ric; iron-sulfur cluster repair di-iron protein\tK07322 ytfE; regulator of cell morphogenesis and NO signaling"
				},
				{
					"name":"E3D81_09885 peptidase M23\tK22719 envC; murein hydrolase activator"
				}
				]
			},
			{
				"name":"99993 Cell motility"
			},
			{
				"name":"99995 Signaling proteins",
				"children":[
				{
					"name":"E3D81_00825 typA; translational GTPase TypA\tK06207 typA; GTP-binding protein"
				},
				{
					"name":"E3D81_11525 HPP family protein\tK07168 K07168; CBS domain-containing membrane protein"
				},
				{
					"name":"E3D81_01720 PhoH family protein\tK06217 phoH; phosphate starvation-inducible protein PhoH and related proteins"
				}
				]
			},
			{
				"name":"99992 Structural proteins",
				"children":[
				{
					"name":"E3D81_07390 OmpH family outer membrane protein\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"E3D81_07395 OmpH family outer membrane protein\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"E3D81_07675 OmpH family outer membrane protein\tK06142 hlpA; outer membrane protein"
				},
				{
					"name":"E3D81_03390 biotin\/lipoyl-binding protein\tK01993 ABC-2.TX; HlyD family secretion protein"
				},
				{
					"name":"E3D81_09235 HlyD family efflux transporter periplasmic adaptor subunit\tK02005 ABC.CD.TX; HlyD family secretion protein"
				},
				{
					"name":"E3D81_07890 creD; cell envelope integrity protein CreD\tK06143 creD; inner membrane protein"
				},
				{
					"name":"E3D81_08065 SusF\/SusE family outer membrane protein\tK21571 susE_F; starch-binding outer membrane protein SusE\/F"
				}
				]
			},
			{
				"name":"99994 Others",
				"children":[
				{
					"name":"E3D81_11775 copper homeostasis protein CutC\tK06201 cutC; copper homeostasis protein"
				},
				{
					"name":"E3D81_00075 apaG; Co2+\/Mg2+ efflux protein ApaG\tK06195 apaG; ApaG protein"
				},
				{
					"name":"E3D81_16690 nosD; nitrous oxide reductase family maturation protein NosD\tK07218 nosD; nitrous oxidase accessory protein"
				},
				{
					"name":"E3D81_03350 hemin-degrading factor\tK07225 hmuS; putative hemin transport protein"
				},
				{
					"name":"E3D81_16695 hypothetical protein\tK19342 nosL; copper chaperone NosL"
				},
				{
					"name":"E3D81_16700 hypothetical protein\tK19342 nosL; copper chaperone NosL"
				}
				]
			}
			]
		},
		{
			"name":"09194 Poorly characterized",
			"children":[
			{
				"name":"99996 General function prediction only",
				"children":[
				{
					"name":"E3D81_07335 GNAT family N-acetyltransferase\tK02348 elaA; ElaA protein"
				},
				{
					"name":"E3D81_02475 tRNA-binding protein\tK06878 K06878; tRNA-binding protein"
				},
				{
					"name":"E3D81_12265 group III truncated hemoglobin\tK06886 glbN; hemoglobin"
				},
				{
					"name":"E3D81_06230 patatin\tK07001 K07001; NTE family protein"
				},
				{
					"name":"E3D81_09740 noncanonical pyrimidine nucleotidase, YjjG family\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"E3D81_15795 HAD family hydrolase\tK07025 K07025; putative hydrolase of the HAD superfamily"
				},
				{
					"name":"E3D81_00920 sufB; Fe-S cluster assembly protein SufB\tK09014 sufB; Fe-S cluster assembly protein SufB"
				},
				{
					"name":"E3D81_00930 sufD; Fe-S cluster assembly protein SufD\tK09015 sufD; Fe-S cluster assembly protein SufD"
				},
				{
					"name":"E3D81_06690 YihY\/virulence factor BrkB family protein\tK07058 K07058; membrane protein"
				},
				{
					"name":"E3D81_07595 YihY\/virulence factor BrkB family protein\tK07058 K07058; membrane protein"
				},
				{
					"name":"E3D81_11450 YihY\/virulence factor BrkB family protein\tK07058 K07058; membrane protein"
				},
				{
					"name":"E3D81_07140 SufE family protein\tK02426 sufE; cysteine desulfuration protein SufE"
				},
				{
					"name":"E3D81_01125 rhodanese-related sulfurtransferase\tK07146 K07146; UPF0176 protein"
				},
				{
					"name":"E3D81_13510 VOC family protein\tK04750 phnB; PhnB protein"
				},
				{
					"name":"E3D81_00950 LemA family protein\tK03744 lemA; LemA protein"
				},
				{
					"name":"E3D81_11290 sprT domain-containing protein\tK02742 sprT; SprT protein"
				},
				{
					"name":"E3D81_10775 DedA family protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"E3D81_17115 DedA family protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"E3D81_17120 DedA family protein\tK03975 dedA; membrane-associated protein"
				},
				{
					"name":"E3D81_00810 phage holin family protein\tK08972 K08972; putative membrane protein"
				},
				{
					"name":"E3D81_08260 DUF420 domain-containing protein\tK08976 K08976; putative membrane protein"
				},
				{
					"name":"E3D81_12020 DUF4142 domain-containing protein\tK08995 K08995; putative membrane protein"
				},
				{
					"name":"E3D81_06550 zinc chelation protein SecC\tK09858 K09858; SEC-C motif domain protein"
				},
				{
					"name":"E3D81_13195 PhnA protein\tK06193 phnA; protein PhnA"
				}
				]
			},
			{
				"name":"99997 Function unknown",
				"children":[
				{
					"name":"E3D81_12830 ankyrin repeat domain-containing protein\tK06867 K06867; uncharacterized protein"
				},
				{
					"name":"E3D81_00960 TPM domain-containing protein\tK06872 K06872; uncharacterized protein"
				},
				{
					"name":"E3D81_03795 TPM domain-containing protein\tK06872 K06872; uncharacterized protein"
				},
				{
					"name":"E3D81_15025 HD domain-containing protein\tK06885 K06885; uncharacterized protein"
				},
				{
					"name":"E3D81_09540 thioredoxin domain-containing protein\tK06888 K06888; uncharacterized protein"
				},
				{
					"name":"E3D81_02550 alpha\/beta fold hydrolase\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"E3D81_05055 alpha\/beta hydrolase\tK06889 K06889; uncharacterized protein"
				},
				{
					"name":"E3D81_14660 HD domain-containing protein\tK06950 K06950; uncharacterized protein"
				},
				{
					"name":"E3D81_03340 pdeM; ligase-associated DNA damage response endonuclease PdeM\tK06953 K06953; uncharacterized protein"
				},
				{
					"name":"E3D81_08995 zinc metallopeptidase\tK06973 K06973; uncharacterized protein"
				},
				{
					"name":"E3D81_04225 N-acetyltransferase\tK06975 K06975; uncharacterized protein"
				},
				{
					"name":"E3D81_09825 N-acetyltransferase\tK06975 K06975; uncharacterized protein"
				},
				{
					"name":"E3D81_12275 N-acetyltransferase\tK06975 K06975; uncharacterized protein"
				},
				{
					"name":"E3D81_08030 CocE\/NonD family hydrolase\tK06978 K06978; uncharacterized protein"
				},
				{
					"name":"E3D81_04095 VOC family protein\tK06996 K06996; uncharacterized protein"
				},
				{
					"name":"E3D81_11485 hypothetical protein\tK06996 K06996; uncharacterized protein"
				},
				{
					"name":"E3D81_13530 VOC family protein\tK06996 K06996; uncharacterized protein"
				},
				{
					"name":"E3D81_12760 glyoxalase\/bleomycin resistance\/extradiol dioxygenase family protein\tK07032 K07032; uncharacterized protein"
				},
				{
					"name":"E3D81_13200 metalloprotease\tK07054 K07054; uncharacterized protein"
				},
				{
					"name":"E3D81_14725 TIGR01777 family protein\tK07071 K07071; uncharacterized protein"
				},
				{
					"name":"E3D81_15765 HEPN domain-containing protein\tK07076 K07076; uncharacterized protein"
				},
				{
					"name":"E3D81_12250 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"E3D81_12450 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"E3D81_13630 sulfite exporter TauE\/SafE family protein\tK07090 K07090; uncharacterized protein"
				},
				{
					"name":"E3D81_08355 metallophosphoesterase\tK07095 K07095; uncharacterized protein"
				},
				{
					"name":"E3D81_15550 metallophosphoesterase\tK07098 K07098; uncharacterized protein"
				},
				{
					"name":"E3D81_11885 YeeE\/YedE family protein\tK07112 K07112; uncharacterized protein"
				},
				{
					"name":"E3D81_11890 YeeE\/YedE family protein\tK07112 K07112; uncharacterized protein"
				},
				{
					"name":"E3D81_00945 FAD-binding protein\tK07137 K07137; uncharacterized protein"
				},
				{
					"name":"E3D81_11390 TIGR01212 family radical SAM protein\tK07139 K07139; uncharacterized protein"
				},
				{
					"name":"E3D81_00135 hypothetical protein\tK07164 K07164; uncharacterized protein"
				},
				{
					"name":"E3D81_07690 yidD; membrane protein insertion efficiency factor YidD\tK08998 K08998; uncharacterized protein"
				},
				{
					"name":"E3D81_10835 hypothetical protein\tK08999 K08999; uncharacterized protein"
				},
				{
					"name":"E3D81_14825 hypothetical protein\tK09004 K09004; uncharacterized protein"
				},
				{
					"name":"E3D81_07330 GatB\/YqeY domain-containing protein\tK09117 K09117; uncharacterized protein"
				},
				{
					"name":"E3D81_08170 DUF493 domain-containing protein\tK09158 K09158; uncharacterized protein"
				},
				{
					"name":"E3D81_07110 glycoside hydrolase family 125 protein\tK09704 K09704; uncharacterized protein"
				},
				{
					"name":"E3D81_08785 hypothetical protein\tK09776 K09776; uncharacterized protein"
				},
				{
					"name":"E3D81_12195 hypothetical protein\tK09780 K09780; uncharacterized protein"
				},
				{
					"name":"E3D81_11980 DUF808 domain-containing protein\tK09781 K09781; uncharacterized protein"
				},
				{
					"name":"E3D81_11435 sulfite exporter TauE\/SafE family protein\tK09792 K09792; uncharacterized protein"
				},
				{
					"name":"E3D81_03090 SIMPL domain-containing protein\tK09797 K09797; uncharacterized protein"
				},
				{
					"name":"E3D81_17005 DUF541 domain-containing protein\tK09807 K09807; uncharacterized protein"
				},
				{
					"name":"E3D81_04030 DUF480 domain-containing protein\tK09915 K09915; uncharacterized protein"
				},
				{
					"name":"E3D81_06555 DUF1508 domain-containing protein\tK09946 K09946; uncharacterized protein"
				},
				{
					"name":"E3D81_01130 hypothetical protein\tK09954 K09954; uncharacterized protein"
				},
				{
					"name":"E3D81_00540 nuclear transport factor 2 family protein\tK09958 K09958; uncharacterized protein"
				},
				{
					"name":"E3D81_01850 DUF779 domain-containing protein\tK09959 K09959; uncharacterized protein"
				},
				{
					"name":"E3D81_08035 TraB\/GumN family protein\tK09973 K09973; uncharacterized protein"
				},
				{
					"name":"E3D81_15425 hypothetical protein\tK09981 K09981; uncharacterized protein"
				},
				{
					"name":"E3D81_00275 prolyl 4-hydroxylase subunit alpha\tK09990 K09990; uncharacterized protein"
				},
				{
					"name":"E3D81_05560 ThuA domain-containing protein\tK09992 K09992; uncharacterized protein"
				},
				{
					"name":"E3D81_16460 DUF47 domain-containing protein\tK07220 K07220; uncharacterized protein"
				}
				]
			}
			]
		}
		]
	}
	]
}
