{
	"name":"sre03110",
	"children":[
	{
		"name":"Heat shock proteins",
		"children":[
		{
			"name":"HSP110"
		},
		{
			"name":"HSP100",
			"children":[
			{
				"name":"PTSG_03175 heat shock protein\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"PTSG_05921 ClpB\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"PTSG_07041 caseinolytic protease C\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			}
			]
		},
		{
			"name":"HSP90",
			"children":[
			{
				"name":"PTSG_02153 90-kDa heat-shock protein\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"PTSG_04395 heat shock protein gp96\tK09487 HSP90B; heat shock protein 90kDa beta"
			},
			{
				"name":"PTSG_09228 heat shock protein 90\tK09488 TRAP1; TNF receptor-associated protein 1"
			}
			]
		},
		{
			"name":"HSP70 \/ DNAK",
			"children":[
			{
				"name":"PTSG_01374 heat shock protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"PTSG_03754 Hsc70-4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"PTSG_10966 heat shock protein 70kDa\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"PTSG_04156 HS24\/P52 protein\tK09489 HSPA4; heat shock 70kDa protein 4"
			},
			{
				"name":"PTSG_07223 preimmunoglobulin heavy chain binding protein\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
			},
			{
				"name":"PTSG_06461 stress 70 protein chaperone\tK09491 HSPA13; heat shock 70kDa protein 13"
			},
			{
				"name":"PTSG_06850 molecular chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"PTSG_10149 chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			}
			]
		},
		{
			"name":"HSP60 \/ Chaperonin",
			"children":[
			{
				"name":"PTSG_11083 T-complex protein 1 subunit alpha\tK09493 CCT1; T-complex protein 1 subunit alpha"
			},
			{
				"name":"PTSG_09309 chaperonin containing TCP1\tK09494 CCT2; T-complex protein 1 subunit beta"
			},
			{
				"name":"PTSG_06459 chaperonin containing TCP1\tK09495 CCT3; T-complex protein 1 subunit gamma"
			},
			{
				"name":"PTSG_11313 chaperonin complex component TCP-1 delta subunit\tK09496 CCT4; T-complex protein 1 subunit delta"
			},
			{
				"name":"PTSG_10217 chaperonin containing TCP1\tK09497 CCT5; T-complex protein 1 subunit epsilon"
			},
			{
				"name":"PTSG_03115 chaperonin\tK09498 CCT6; T-complex protein 1 subunit zeta"
			},
			{
				"name":"PTSG_06393 chaperonin subunit 1\tK09499 CCT7; T-complex protein 1 subunit eta"
			},
			{
				"name":"PTSG_12673 T-complex protein 1 subunit theta\tK09500 CCT8; T-complex protein 1 subunit theta"
			},
			{
				"name":"PTSG_09311 heat shock protein 60\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"HSP47"
		},
		{
			"name":"HSP40 \/ DNAJ",
			"children":[
			{
				"name":"PTSG_05441 DnaJ-lik protein\tK09502 DNAJA1; DnaJ homolog subfamily A member 1"
			},
			{
				"name":"PTSG_03843 Dnaja4 protein\tK09503 DNAJA2; DnaJ homolog subfamily A member 2"
			},
			{
				"name":"PTSG_04327 dnaJ protein\tK09504 DNAJA3; DnaJ homolog subfamily A member 3"
			},
			{
				"name":"PTSG_12963 uncharacterized protein\tK09506 DNAJA5; DnaJ homolog subfamily A member 5"
			},
			{
				"name":"PTSG_01179 DnaJ domain-containing protein\tK09510 DNAJB4; DnaJ homolog subfamily B member 4"
			},
			{
				"name":"PTSG_07464 chaperone\tK09512 DNAJB6; DnaJ homolog subfamily B member 6"
			},
			{
				"name":"PTSG_01124 chaperone protein dnaJ\tK09517 DNAJB11; DnaJ homolog subfamily B member 11"
			},
			{
				"name":"PTSG_10855 uncharacterized protein\tK09518 DNAJB12; DnaJ homolog subfamily B member 12"
			},
			{
				"name":"PTSG_08182 uncharacterized protein\tK09519 DNAJB13; DnaJ homolog subfamily B member 13"
			},
			{
				"name":"PTSG_05570 uncharacterized protein\tK09522 DNAJC2; DnaJ homolog subfamily C member 2"
			},
			{
				"name":"PTSG_01415 uncharacterized protein\tK09523 DNAJC3; DnaJ homolog subfamily C member 3"
			},
			{
				"name":"PTSG_05053 uncharacterized protein\tK09527 DNAJC7; DnaJ homolog subfamily C member 7"
			},
			{
				"name":"PTSG_03450 uncharacterized protein\tK09528 DNAJC8; DnaJ homolog subfamily C member 8"
			},
			{
				"name":"PTSG_11089 uncharacterized protein\tK09529 DNAJC9; DnaJ homolog subfamily C member 9"
			},
			{
				"name":"PTSG_05593 molecular chaperone DnaJ\tK09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]"
			},
			{
				"name":"PTSG_10389 uncharacterized protein\tK09531 DNAJC11; DnaJ homolog subfamily C member 11"
			},
			{
				"name":"PTSG_05282 uncharacterized protein\tK09532 DNAJC12; DnaJ homolog subfamily C member 12"
			},
			{
				"name":"PTSG_11261 RME8 protein\tK09533 DNAJC13; DnaJ homolog subfamily C member 13"
			},
			{
				"name":"PTSG_09562 Dnajc17 protein\tK09537 DNAJC17; DnaJ homolog subfamily C member 17"
			},
			{
				"name":"PTSG_09598 Dnajc17 protein\tK09537 DNAJC17; DnaJ homolog subfamily C member 17"
			},
			{
				"name":"PTSG_01178 import inner membrane translocase subunit TIM14\tK09539 DNAJC19; DnaJ homolog subfamily C member 19"
			},
			{
				"name":"PTSG_09941 uncharacterized protein\tK19370 DNAJC22; DnaJ homolog subfamily C member 22"
			},
			{
				"name":"PTSG_04855 uncharacterized protein\tK09540 SEC63; translocation protein SEC63"
			},
			{
				"name":"PTSG_11569 uncharacterized protein\tK19371 DNAJC25; DnaJ homolog subfamily C member 25"
			},
			{
				"name":"PTSG_11628 uncharacterized protein\tK19372 DNAJC27; DnaJ homolog subfamily C member 27"
			},
			{
				"name":"PTSG_07341 uncharacterized protein\tK04082 hscB; molecular chaperone HscB"
			}
			]
		},
		{
			"name":"HSP33"
		},
		{
			"name":"HSP24",
			"children":[
			{
				"name":"PTSG_05721 uncharacterized protein\tK03687 GRPE; molecular chaperone GrpE"
			}
			]
		},
		{
			"name":"HSP20",
			"children":[
			{
				"name":"PTSG_02307 uncharacterized protein\tK19369 HSPB11; heat shock protein beta-11"
			},
			{
				"name":"PTSG_03949 low-molecular-weight heat shock protein\tK13993 HSP20; HSP20 family protein"
			},
			{
				"name":"PTSG_07162 heat shock protein\tK13993 HSP20; HSP20 family protein"
			},
			{
				"name":"PTSG_07184 heat shock protein\tK13993 HSP20; HSP20 family protein"
			}
			]
		},
		{
			"name":"HSP15"
		},
		{
			"name":"HSP10",
			"children":[
			{
				"name":"PTSG_06138 heat shock protein 10\tK04078 groES; chaperonin GroES"
			}
			]
		},
		{
			"name":"GimC",
			"children":[
			{
				"name":"PTSG_08784 uncharacterized protein\tK09548 PFDN1; prefoldin subunit 1"
			},
			{
				"name":"PTSG_04898 uncharacterized protein\tK09549 PFDN2; prefoldin subunit 2"
			},
			{
				"name":"PTSG_04187 uncharacterized protein\tK04797 pfdA; prefoldin alpha subunit"
			},
			{
				"name":"PTSG_08641 uncharacterized protein\tK04798 pfdB; prefoldin beta subunit"
			}
			]
		}
		]
	},
	{
		"name":"Other chaperones and cochaperones",
		"children":[
		{
			"name":"Calnexin \/ calreticulin",
			"children":[
			{
				"name":"PTSG_04660 SmIrV1 protein\tK08054 CANX; calnexin"
			},
			{
				"name":"PTSG_04786 calreticulin\tK08057 CALR; calreticulin"
			}
			]
		},
		{
			"name":"DegP \/ HtrA"
		},
		{
			"name":"AAA proteases",
			"children":[
			{
				"name":"PTSG_01372 26S protease regulatory subunit\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
			},
			{
				"name":"PTSG_09695 AFG3-like protein 2\tK08956 AFG3; AFG3 family protein [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"PapD"
		},
		{
			"name":"SecB"
		},
		{
			"name":"Sti1 \/ p60"
		},
		{
			"name":"Cdc37 \/ p50",
			"children":[
			{
				"name":"PTSG_04328 uncharacterized protein\tK09554 CDC37; cell division cycle protein 37"
			}
			]
		},
		{
			"name":"BAG",
			"children":[
			{
				"name":"PTSG_10068 uncharacterized protein\tK09555 BAG1; BCL2-associated athanogene 1"
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"PTSG_11164 uncharacterized protein\tK09560 ST13; suppressor of tumorigenicity protein 13"
			},
			{
				"name":"PTSG_00870 uncharacterized protein\tK09562 HSPBP1; hsp70-interacting protein"
			},
			{
				"name":"PTSG_04863 uncharacterized protein\tK19375 HSPBAP1; HSPB1-associated protein 1"
			},
			{
				"name":"PTSG_12738 uncharacterized protein\tK19375 HSPBAP1; HSPB1-associated protein 1"
			},
			{
				"name":"PTSG_04884 uncharacterized protein\tK16729 CHORDC1; cysteine and histidine-rich domain-containing protein"
			},
			{
				"name":"PTSG_06979 uncharacterized protein\tK21991 UNC45; protein unc-45"
			},
			{
				"name":"PTSG_06150 uncharacterized protein\tK16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha"
			},
			{
				"name":"PTSG_06951 uncharacterized protein\tK24962 CCDC47; PAT complex subunit CCDC47"
			},
			{
				"name":"PTSG_07308 uncharacterized protein\tK25366 MESD; LRP chaperone MESD"
			},
			{
				"name":"PTSG_00408 uncharacterized protein\tK26216 AHSA1; activator of Hsp90 ATPase protein 1"
			},
			{
				"name":"PTSG_03566 uncharacterized protein\tK28128 HYPK; huntingtin-interacting protein K"
			},
			{
				"name":"PTSG_08141 uncharacterized protein\tK28206 PDCL; phosducin-like protein"
			}
			]
		}
		]
	},
	{
		"name":"Intramolecular chaperones",
		"children":[
		{
			"name":"Subtilisin family",
			"children":[
			{
				"name":"PTSG_07047 uncharacterized protein\tK08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]"
			},
			{
				"name":"PTSG_00429 protease PC6 isoform A\tK08654 PCSK5; proprotein convertase subtilisin\/kexin type 5 [EC:3.4.21.-]"
			},
			{
				"name":"PTSG_05153 laminin alpha 5 chain\tK08654 PCSK5; proprotein convertase subtilisin\/kexin type 5 [EC:3.4.21.-]"
			},
			{
				"name":"PTSG_01230 uncharacterized protein\tK01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]"
			},
			{
				"name":"PTSG_08634 uncharacterized protein\tK01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]"
			},
			{
				"name":"PTSG_10288 hypothetical protein, variant\tK01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]"
			}
			]
		},
		{
			"name":"Papain family",
			"children":[
			{
				"name":"PTSG_05183 cathepsin B\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"PTSG_07950 uncharacterized protein\tK01363 CTSB; cathepsin B [EC:3.4.22.1]"
			},
			{
				"name":"PTSG_05727 uncharacterized protein\tK01365 CTSL; cathepsin L [EC:3.4.22.15]"
			}
			]
		},
		{
			"name":"Other peptidases"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"PTSG_01337 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"PTSG_03917 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"PTSG_05033 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"PTSG_09649 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"PTSG_11616 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"PTSG_11831 uncharacterized protein\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			}
			]
		}
		]
	},
	{
		"name":"Protein folding catalysts",
		"children":[
		{
			"name":"Peptidyl prolyl isomerase",
			"children":[
			{
				"name":"Cyclophilin",
				"children":[
				{
					"name":"PTSG_07115 peptidyl-prolyl cis-trans isomerase E\tK09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_01472 cyclophilin\tK09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_03948 peptidyl-prolyl cis-trans isomerase B\tK09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_08871 peptidylprolyl isomerase H\tK09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_12016 peptidyl-prolyl cis-trans isomerase\tK12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_08050 Ppil2 protein\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_03391 cyp10l\tK12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_07932 uncharacterized protein\tK12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_12788 uncharacterized protein\tK12739 PPIL6; peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_10832 peptidyl-prolyl cis-trans isomerase\tK12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_01085 cyclophilin-16\tK12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_03188 ran-binding protein 1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
				}
				]
			},
			{
				"name":"FKBP",
				"children":[
				{
					"name":"PTSG_01733 peptidyl-prolyl cis-trans isomerase FKBP2\tK09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_03068 FK506-binding protein\tK09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"Parvulin",
				"children":[
				{
					"name":"PTSG_01411 peptidyl-prolyl cis-trans isomerase pin1\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_02690 peptidylprolyl cis\/trans isomerase\tK09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]"
				},
				{
					"name":"PTSG_08451 parvulin-type peptidyl-prolyl cis-trans isomerase\tK09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"Protein disulfide isomerase",
			"children":[
			{
				"name":"PTSG_10131 thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"PTSG_12256 thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"PTSG_03575 uncharacterized protein\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"PTSG_01755 glutaredoxin\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"PTSG_03280 uncharacterized protein\tK17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1"
			},
			{
				"name":"PTSG_08227 uncharacterized protein\tK17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1"
			},
			{
				"name":"PTSG_02152 uncharacterized protein\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_07112 disulfide isomerase\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_07668 disulfide isomerase\tK08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_00873 disulfide isomerase\tK09582 PDIA4; protein disulfide-isomerase A4 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_09710 uncharacterized protein\tK09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_02776 uncharacterized protein\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_03920 Pdip5 protein\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_04480 uncharacterized protein\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
			},
			{
				"name":"PTSG_00605 disulfide isomerase PDI5\tK13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]"
			}
			]
		}
		]
	}
	]
}