{ "name":"ssen03019", "children":[ { "name":"Eukaryotic type", "children":[ { "name":"mRNA processing factors", "children":[ { "name":"5' end processing", "children":[ { "name":"Capping factors", "children":[ { "name":"122786853 rnmt; mRNA cap guanine-N7 methyltransferase isoform X1\tK00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]" }, { "name":"122784009 rngtt; mRNA-capping enzyme\tK13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]" }, { "name":"122769252 cdk7; cyclin-dependent kinase 7\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]" }, { "name":"122784425 cmtr1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1\tK14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]" }, { "name":"122772837 cmtr2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2\tK14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]" }, { "name":"122772857 RNA guanine-N7 methyltransferase activating subunit-like\tK18708 FAM103A1; RNMT-activating mini protein" } ] }, { "name":"Cap binding complex", "children":[ { "name":"122778712 nuclear cap-binding protein subunit 1\tK12882 NCBP1; nuclear cap-binding protein subunit 1" }, { "name":"122780406 ncbp2; nuclear cap-binding protein subunit 2\tK12883 NCBP2; nuclear cap-binding protein subunit 2" } ] } ] }, { "name":"3' end processing", "children":[ { "name":"Pre-mRNA cleavage factor Im (CFIm)", "children":[ { "name":"122772450 nudt21; cleavage and polyadenylation specificity factor subunit 5\tK14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5" }, { "name":"122767006 cpsf6; cleavage and polyadenylation specificity factor subunit 6 isoform X1\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" }, { "name":"122772360 cleavage and polyadenylation specificity factor subunit 7-like\tK14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6\/7" } ] }, { "name":"Pre-mRNA cleavage factor IIm (CFIIm)", "children":[ { "name":"122778940 clp1; polyribonucleotide 5'-hydroxyl-kinase Clp1\tK14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]" }, { "name":"122780068 pcf11; pre-mRNA cleavage complex 2 protein Pcf11\tK14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11" } ] }, { "name":"Cleavage and polyadenylation specificity factor (CPSF) complex", "children":[ { "name":"122786863 cpsf1; cleavage and polyadenylation specificity factor subunit 1\tK14401 CPSF1; cleavage and polyadenylation specificity factor subunit 1" }, { "name":"122784422 cpsf2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"122782545 cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"122784345 cleavage and polyadenylation specificity factor subunit 3-like\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"122784718 cpsf4; cleavage and polyadenylation specificity factor subunit 4\tK14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4" }, { "name":"122760338 fip1l1b; pre-mRNA 3'-end-processing factor FIP1 isoform X1\tK14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1" }, { "name":"122774537 wdr33; pre-mRNA 3' end processing protein WDR33\tK15542 PFS2; polyadenylation factor subunit 2" }, { "name":"122768142 wdr82; WD repeat-containing protein 82\tK14962 WDR82; COMPASS component SWD2" }, { "name":"122759222 ppp1cab; protein phosphatase 1, catalytic subunit, alpha isozyme b\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122760207 serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122765921 serine\/threonine-protein phosphatase PP1-beta catalytic subunit-like\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122766757 ppp1caa; protein phosphatase 1, catalytic subunit, alpha isozyme a\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122769805 serine\/threonine-protein phosphatase PP1-gamma catalytic subunit A\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122783022 ppp1cb; serine\/threonine-protein phosphatase PP1-beta catalytic subunit\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]" }, { "name":"122768428 ssu72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72\tK15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]" } ] }, { "name":"Cleavage stimulation factor (CSTF) complex", "children":[ { "name":"122760548 cstf1; cleavage stimulation factor subunit 1\tK14406 CSTF1; cleavage stimulation factor subunit 1" }, { "name":"122778254 cstf2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"122772256 cstf3; cleavage stimulation factor subunit 3\tK14408 CSTF3; cleavage stimulation factor subunit 3" }, { "name":"122765584 sympk; symplekin\tK06100 SYMPK; symplekin" } ] }, { "name":"U7-dependent histone pre-mRNA processing factors", "children":[ { "name":"122768167 snrpb; small nuclear ribonucleoprotein-associated proteins B and B'\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'" }, { "name":"122758133 small nuclear ribonucleoprotein Sm D3\tK11088 SNRPD3; small nuclear ribonucleoprotein D3" }, { "name":"122767997 snrpe; small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E" }, { "name":"122766825 snrpf; small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F" }, { "name":"122759974 snrpg; small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"122776792 small nuclear ribonucleoprotein G-like\tK11099 SNRPG; small nuclear ribonucleoprotein G" }, { "name":"122786485 lsm10; U7 snRNA-associated Sm-like protein LSm10\tK25591 LSM10; U7 snRNA-associated Sm-like protein LSm10" }, { "name":"122778979 lsm11; U7 snRNA-associated Sm-like protein LSm11\tK25592 LSM11; U7 snRNA-associated Sm-like protein LSm11" }, { "name":"122784422 cpsf2; cleavage and polyadenylation specificity factor subunit 2\tK14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2" }, { "name":"122782545 cleavage and polyadenylation specificity factor subunit 3\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"122784345 cleavage and polyadenylation specificity factor subunit 3-like\tK14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]" }, { "name":"122778254 cstf2; cleavage stimulation factor subunit 2 isoform X1\tK14407 CSTF2; cleavage stimulation factor subunit 2" }, { "name":"122765584 sympk; symplekin\tK06100 SYMPK; symplekin" }, { "name":"122778891 histone RNA hairpin-binding protein\tK18710 SLBP; histone RNA hairpin-binding protein" }, { "name":"122779999 slbp2; stem-loop binding protein 2\tK18710 SLBP; histone RNA hairpin-binding protein" }, { "name":"122784481 casp8ap2; CASP8-associated protein 2\tK25593 CASP8AP2; CASP8-associated protein 2" } ] }, { "name":"DRB sensitivity inducing factor (DSIF) complex", "children":[ { "name":"122779257 supt4h1; transcription elongation factor SPT4\tK15171 SUPT4H1; transcription elongation factor SPT4" }, { "name":"122761686 transcription elongation factor SPT5 isoform X1\tK15172 SUPT5H; transcription elongation factor SPT5" }, { "name":"122773536 transcription elongation factor SPT5-like\tK15172 SUPT5H; transcription elongation factor SPT5" } ] }, { "name":"N6-methyltransferase complex", "children":[ { "name":"122766248 mettl3; N6-adenosine-methyltransferase subunit METTL3\tK05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]" }, { "name":"122771635 mettl14; N6-adenosine-methyltransferase non-catalytic subunit\tK23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit" }, { "name":"122781254 mettl4; N(6)-adenine-specific methyltransferase METTL4 isoform X1\tK24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]" }, { "name":"122773745 mettl16; RNA N6-adenosine-methyltransferase mettl16\tK11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]" }, { "name":"122783976 pre-mRNA-splicing regulator WTAP\tK22824 WTAP; pre-mRNA-splicing regulator WTAP" }, { "name":"122775073 virma; protein virilizer homolog isoform X1\tK22910 VIRMA; protein virilizer" }, { "name":"122767999 rbm15b; putative RNA-binding protein 15B\tK13190 RBM15; RNA-binding protein 15" }, { "name":"122768049 RNA-binding protein 15-like\tK13190 RBM15; RNA-binding protein 15" }, { "name":"122777075 rbm15; RNA-binding protein 15\tK13190 RBM15; RNA-binding protein 15" }, { "name":"122762345 zc3h13; LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 13\tK22909 ZC3H13; zinc finger CCCH domain-containing protein 13" }, { "name":"122766011 cbll1; E3 ubiquitin-protein ligase Hakai isoform X1\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]" } ] }, { "name":"Poly(A) addition factors", "children":[ { "name":"122781739 papolg; poly(A) polymerase gamma isoform X1\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"122784478 poly(A) polymerase type 3-like\tK14376 PAP; poly(A) polymerase [EC:2.7.7.19]" }, { "name":"122769249 tent2; poly(A) RNA polymerase GLD2\tK14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]" }, { "name":"122759261 tut1; speckle targeted PIP5K1A-regulated poly(A) polymerase\tK18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]" } ] }, { "name":"Negative regulators of mRNA 3' end processing", "children":[ { "name":"122763523 bard1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1" }, { "name":"122772583 rbm26; RNA-binding protein 26\tK13192 RBM26; RNA-binding protein 26" }, { "name":"122772636 fto; alpha-ketoglutarate-dependent dioxygenase FTO\tK19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"122771632 alkbh5; RNA demethylase ALKBH5\tK10767 ALKBH5; mRNA N6-methyladenine demethylase [EC:1.14.11.53]" }, { "name":"122768593 tardbpb; TAR DNA-binding protein 43 isoform X1\tK23600 TARDBP; TAR DNA-binding protein 43" }, { "name":"122776824 tardbpa; TAR DNA binding protein, like isoform X1\tK23600 TARDBP; TAR DNA-binding protein 43" } ] } ] }, { "name":"Other processing factors", "children":[ { "name":"122773273 dhx40; probable ATP-dependent RNA helicase DHX40\tK18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]" }, { "name":"122762145 kin; DNA\/RNA-binding protein KIN17\tK13102 KIN; DNA\/RNA-binding protein KIN17" }, { "name":"122763809 mettl8; mRNA N(3)-methylcytidine methyltransferase METTL8\tK24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]" }, { "name":"122785797 mettl22; methyltransferase-like protein 22 isoform X1\tK23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]" }, { "name":"122775166 tent5aa; terminal nucleotidyltransferase 5A\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"122775266 tent5ba; terminal nucleotidyltransferase 5ba\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"122784310 terminal nucleotidyltransferase 5A-like\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"122786658 terminal nucleotidyltransferase 5A-like\tK23033 TENT5A_B; terminal nucleotidyltransferase 5A\/B [EC:2.7.7.-]" }, { "name":"122765367 tent5c; terminal nucleotidyltransferase 5C\tK23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]" }, { "name":"122758797 zc3h14; zinc finger CCCH domain-containing protein 14 isoform X1\tK23038 ZC3H14; zinc finger CCCH domain-containing protein 14" }, { "name":"122766947 serrate RNA effector molecule homolog\tK27103 SRRT; serrate RNA effector molecule" }, { "name":"122769430 serrate RNA effector molecule homolog\tK27103 SRRT; serrate RNA effector molecule" }, { "name":"122779644 srrt; serrate RNA effector molecule homolog\tK27103 SRRT; serrate RNA effector molecule" } ] } ] }, { "name":"mRNA surveillance and transport factors", "children":[ { "name":"Transport factors", "children":[ { "name":"EJC complex", "children":[ { "name":"122774215 rbm8a; RNA-binding protein 8A\tK12876 RBM8A; RNA-binding protein 8A" }, { "name":"122780336 magoh; protein mago nashi homolog\tK12877 MAGOH; protein mago nashi" }, { "name":"122770896 THO complex subunit 4-like isoform X1\tK12881 THOC4; THO complex subunit 4" }, { "name":"122785788 alyref; THO complex subunit 4 isoform X1\tK12881 THOC4; THO complex subunit 4" }, { "name":"122770582 eif4a3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"122768774 ccdc174; coiled-coil domain-containing protein 174\tK25178 CCDC174; coiled-coil domain-containing protein 174" }, { "name":"122785142 casc3; protein CASC3\tK14323 CASC3; protein CASC3" }, { "name":"122765060 sap18; histone deacetylase complex subunit SAP18\tK14324 SAP18; histone deacetylase complex subunit SAP18" }, { "name":"122782833 pnn; pinin\tK13114 PNN; pinin" }, { "name":"122766139 acin1b; apoptotic chromatin condensation inducer 1b isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"122773775 apoptotic chromatin condensation inducer in the nucleus-like isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"122773856 acin1a; calponin homology domain-containing protein DDB_G0272472 isoform X1\tK12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus" }, { "name":"122759650 RNA-binding protein with serine-rich domain 1-like\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1" }, { "name":"122784701 RNA-binding protein with serine-rich domain 1-like\tK14325 RNPS1; RNA-binding protein with serine-rich domain 1" }, { "name":"122761254 srrm1; serine\/arginine repetitive matrix protein 1 isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1" }, { "name":"122777457 serine\/arginine repetitive matrix protein 1-like isoform X1\tK13171 SRRM1; serine\/arginine repetitive matrix protein 1" } ] }, { "name":"TREX complex", "children":[ { "name":"122781128 thoc1; THO complex subunit 1\tK12878 THOC1; THO complex subunit 1" }, { "name":"122779371 thoc2; THO complex subunit 2 isoform X1\tK12879 THOC2; THO complex subunit 2" }, { "name":"122778570 thoc3; THO complex subunit 3\tK12880 THOC3; THO complex subunit 3" }, { "name":"122770896 THO complex subunit 4-like isoform X1\tK12881 THOC4; THO complex subunit 4" }, { "name":"122785788 alyref; THO complex subunit 4 isoform X1\tK12881 THOC4; THO complex subunit 4" }, { "name":"122769631 thoc5; THO complex subunit 5 homolog\tK13174 THOC5; THO complex subunit 5" }, { "name":"122785123 thoc6; THO complex subunit 6 homolog\tK13175 THOC6; THO complex subunit 6" }, { "name":"122786439 chtopa; chromatin target of PRMT1a\tK28424 CHTOP; chromatin target of PRMT1 protein" } ] }, { "name":"TREX-2 complex", "children":[ { "name":"122765309 pcid2; PCI domain-containing protein 2\tK23801 PCID2; nuclear mRNA export protein PCID2\/THP1" }, { "name":"122760157 sem1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1" }, { "name":"122774878 transcription and mRNA export factor ENY2-2\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"122786583 transcription and mRNA export factor ENY2-2-like\tK11368 ENY2; enhancer of yellow 2 transcription factor" }, { "name":"122778109 cetn2; caltractin\tK10840 CETN2; centrin-2" }, { "name":"122787123 cetn3; centrin-3\tK16466 CETN3; centrin-3" }, { "name":"122758994 germinal-center associated nuclear protein\tK24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]" } ] }, { "name":"Nuclear pore complex", "children":[ { "name":"122778729 nucleoprotein TPR-like\tK09291 TPR; nucleoprotein TPR" }, { "name":"122780638 tprb; translocated promoter region b, nuclear basket protein isoform X1\tK09291 TPR; nucleoprotein TPR" }, { "name":"122767576 rae1; mRNA export factor isoform X1\tK14298 RAE1; mRNA export factor" }, { "name":"122768459 sec13; protein SEC13 homolog\tK14004 SEC13; protein transport protein SEC13" }, { "name":"122766064 nup37; nucleoporin Nup37\tK14302 NUP37; nuclear pore complex protein Nup37" }, { "name":"122784940 nup85; nuclear pore complex protein Nup85\tK14304 NUP85; nuclear pore complex protein Nup85" }, { "name":"122784042 nup43; nucleoporin Nup43\tK14305 NUP43; nuclear pore complex protein Nup43" }, { "name":"122760779 nup50; nuclear pore complex protein Nup50\tK14295 NUP50; nuclear pore complex protein Nup50" }, { "name":"122758699 nup54; nucleoporin p54 isoform X1\tK14308 NUP54; nuclear pore complex protein Nup54" }, { "name":"122765182 nup62l; nucleoporin 62 like\tK14306 NUP62; nuclear pore complex protein Nup62" }, { "name":"122761009 nup93; nuclear pore complex protein Nup93\tK14309 NUP93; nuclear pore complex protein Nup93" }, { "name":"122779794 nup98; nuclear pore complex protein Nup98-Nup96 isoform X1\tK14297 NUP98; nuclear pore complex protein Nup98-Nup96" }, { "name":"122766519 nup107; nuclear pore complex protein Nup107\tK14301 NUP107; nuclear pore complex protein Nup107" }, { "name":"122771232 nup133; LOW QUALITY PROTEIN: nuclear pore complex protein Nup133\tK14300 NUP133; nuclear pore complex protein Nup133" }, { "name":"122758090 nup188; nucleoporin NUP188\tK14311 NUP188; nuclear pore complex protein Nup188" }, { "name":"122786917 nup153; nuclear pore complex protein Nup153 isoform X1\tK14296 NUP153; nuclear pore complex protein Nup153" }, { "name":"122758437 nup155; nuclear pore complex protein Nup155\tK14312 NUP155; nuclear pore complex protein Nup155" }, { "name":"122762335 nup160; nuclear pore complex protein Nup160\tK14303 NUP160; nuclear pore complex protein Nup160" }, { "name":"122762897 nup35; nucleoporin NUP35 isoform X1\tK14313 NUP35; nuclear pore complex protein Nup53" }, { "name":"122776330 nup205; nuclear pore complex protein Nup205\tK14310 NUP205; nuclear pore complex protein Nup205" }, { "name":"122777517 nup210; nuclear pore membrane glycoprotein 210\tK14314 NUP210; nuclear pore complex protein Nup210" }, { "name":"122758293 nuclear pore complex protein Nup214-like isoform X1\tK14317 NUP214; nuclear pore complex protein Nup214" }, { "name":"122780046 pom121; nuclear envelope pore membrane protein POM 121\tK14316 POM121; nuclear pore complex protein Nup121" }, { "name":"122773189 nup58; nucleoporin p58\/p45 isoform X1\tK14307 NUPL1; nucleoporin p58\/p45" }, { "name":"122786000 nup42; nucleoporin NUP42\tK14321 NUPL2; nucleoporin-like protein 2" }, { "name":"122780893 ndc1; nucleoporin NDC1 isoform X1\tK14315 NDC1; nucleoporin NDC1" }, { "name":"122775146 seh1l; nucleoporin SEH1 isoform X1\tK14299 SEH1; nucleoporin SEH1" }, { "name":"122774425 ranbp2; E3 SUMO-protein ligase RanBP2 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]" }, { "name":"122782707 senp2; sentrin-specific protease 2\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]" }, { "name":"122776644 aaas; aladin isoform X1\tK14320 AAAS; aladin" }, { "name":"122787123 cetn3; centrin-3\tK16466 CETN3; centrin-3" }, { "name":"122769565 gle1; nucleoporin GLE1 isoform X1\tK18723 GLE1; nucleoporin GLE1" }, { "name":"122778964 nxf1a; nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"122778498 nxt2; NTF2-related export protein 2\tK14285 NXT1_2; NTF2-related export protein 1\/2" } ] }, { "name":"Ran-mediated transport factors", "children":[ { "name":"122778957 ran; GTP-binding nuclear protein Ran\tK07936 RAN; GTP-binding nuclear protein Ran" }, { "name":"122772768 anp32a; acidic leucine-rich nuclear phosphoprotein 32 family member A\tK18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A\/C\/D" }, { "name":"122767208 acidic leucine-rich nuclear phosphoprotein 32 family member B-like isoform X1\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B" }, { "name":"122770839 anp32b; acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1\tK18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B" }, { "name":"122780520 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"122782645 elavl1a; ELAV-like protein 1a isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"122766981 elavl2; ELAV-like protein 2 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"122780690 elavl4; ELAV-like protein 4 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"122785011 elavl3; ELAV-like protein 3 isoform X1\tK13208 ELAVL2_3_4; ELAV like protein 2\/3\/4" }, { "name":"122778013 faf2; FAS-associated factor 2 isoform X1\tK18726 FAF2; FAS-associated factor 2" }, { "name":"122769704 transitional endoplasmic reticulum ATPase\tK13525 VCP; transitional endoplasmic reticulum ATPase" }, { "name":"122770512 zgc:136908; transitional endoplasmic reticulum ATPase isoform X1\tK13525 VCP; transitional endoplasmic reticulum ATPase" }, { "name":"122783134 vcpkmt; protein-lysine methyltransferase METTL21D isoform X1\tK21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]" }, { "name":"122771217 transportin-2 isoform X1\tK18727 TNPO2; transportin-2" }, { "name":"122784899 transportin-2-like isoform X1\tK18727 TNPO2; transportin-2" }, { "name":"122761904 xpo1a; exportin-1\tK14290 XPO1; exportin-1" }, { "name":"122761937 exportin-1 isoform X1\tK14290 XPO1; exportin-1" }, { "name":"122758296 xpo7; exportin-7 isoform X1\tK18460 XPO7; exportin-7" }, { "name":"122761447 ran GTPase-activating protein 1-like\tK14319 RANGAP1; Ran GTPase-activating protein 1" }, { "name":"122785786 rangap1a; ran GTPase-activating protein 1a isoform X1\tK14319 RANGAP1; Ran GTPase-activating protein 1" }, { "name":"122776546 nutf2; nuclear transport factor 2\tK28773 NUTF2; nuclear transport factor 2" }, { "name":"122786052 nuclear transport factor 2-like\tK28773 NUTF2; nuclear transport factor 2" } ] }, { "name":"eIF4F and regulatory proteins", "children":[ { "name":"122770821 eif4e2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122778175 eukaryotic translation initiation factor 4E-1A-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122782326 eif4e1c; eukaryotic translation initiation factor 4E family member 1c\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122782412 eif4eb; eukaryotic translation initiation factor 4eb\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122767130 eif4a1a; eukaryotic translation initiation factor 4A1A\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122768810 eif4a2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122781812 eukaryotic initiation factor 4A-II-like\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122767593 eif4g1a; eukaryotic translation initiation factor 4 gamma 1a isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122768420 eif4g3a; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122772487 eif4g2a; eukaryotic translation initiation factor 4 gamma 2a\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122773276 eukaryotic translation initiation factor 4 gamma 1-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122775851 eif4g2b; eukaryotic translation initiation factor 4 gamma 2b\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122775580 eif4ba; eukaryotic translation initiation factor 4Ba isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"122773656 eif4h; eukaryotic translation initiation factor 4H isoform X1\tK24086 EIF4H; translation initiation factor 4H" }, { "name":"122769070 eukaryotic translation initiation factor 4E-binding protein 1-like\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1" }, { "name":"122787050 eukaryotic translation initiation factor 4E-binding protein 1-like\tK07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1" }, { "name":"122760266 eif4ebp2; eukaryotic translation initiation factor 4E-binding protein 2\tK18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2" }, { "name":"122778827 eif4ebp3l; eukaryotic translation initiation factor 4E-binding protein 3-like\tK18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3" }, { "name":"122768063 eif4enif1; eukaryotic translation initiation factor 4E transporter\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"122783043 angel1; protein angel homolog 1\tK18729 ANGEL; protein angel" }, { "name":"122783616 angel2; protein angel homolog 2 isoform X1\tK18729 ANGEL; protein angel" }, { "name":"122765791 fxr2; fragile X mental retardation syndrome-related protein 2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122778452 fmr1; synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122780770 fxr1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122759900 cyfip1; cytoplasmic FMR1-interacting protein 1 homolog\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"122778396 cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"122779992 gemin5; gem-associated protein 5\tK13133 GEMIN5; gem associated protein 5" }, { "name":"122783075 tacc3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"122772498 cpeb1b; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122778525 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122779448 cpeb4b; cytoplasmic polyadenylation element-binding protein 4b isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122781049 cpeb2; cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122782128 cpeb3; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122762895 putative ATP-dependent RNA helicase an3 isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"122785191 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"122766487 gigyf1a; GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"122773497 gigyf2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"122761256 pabpc4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122774764 polyadenylate-binding protein 1A\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122786804 polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122770080 paip1; polyadenylate-binding protein-interacting protein 1\tK14322 PAIP1; polyadenylate-binding protein-interacting protein 1" }, { "name":"122764819 polyadenylate-binding protein-interacting protein 2-like\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2" }, { "name":"122766778 paip2b; polyadenylate-binding protein-interacting protein 2B isoform X1\tK27470 PAIP2; polyadenylate-binding protein-interacting protein 2" }, { "name":"122786634 skiv2l; helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"122776233 deaf1; deformed epidermal autoregulatory factor 1 homolog isoform X1\tK23041 DEAF1; deformed epidermal autoregulatory factor 1" }, { "name":"122778675 mcts1; malignant T-cell-amplified sequence 1\tK07575 MCTS; malignant T-cell-amplified sequence" }, { "name":"122758573 denr; density-regulated protein\tK24272 DENR; density-regulated protein" } ] }, { "name":"APOBEC1-ACF complex", "children":[ { "name":"122762214 a1cf; APOBEC1 complementation factor isoform X1\tK24978 A1CF; APOBEC1 complementation factor" } ] }, { "name":"Other transport factors", "children":[ { "name":"122777415 pym1; partner of Y14 and mago\tK14294 WIBG; partner of Y14 and mago" }, { "name":"122776975 hnrnpa1b; heterogeneous nuclear ribonucleoprotein A1b isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"122786686 hnrnpa3; heterogeneous nuclear ribonucleoprotein A3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"122768127 RNA-binding protein Musashi homolog 1-like isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"122770210 msi1b; RNA-binding protein Musashi homolog 1b isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"122774007 msi2b; RNA-binding protein Musashi homolog 2b isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"122779366 RNA-binding protein Musashi homolog 2 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"122781333 dazap1; DAZ-associated protein 1 isoform X1\tK14411 MSI; RNA-binding protein Musashi" }, { "name":"122783773 hbs1l; HBS1-like protein isoform X1\tK14416 HBS1; elongation factor 1 alpha-like protein" }, { "name":"122759221 pelo; protein pelota homolog\tK06965 PELO; protein pelota" }, { "name":"122772681 pabpn1l; embryonic polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"122777268 pabpn1; polyadenylate-binding protein 2 isoform X1\tK14396 PABPN1; polyadenylate-binding protein 2" }, { "name":"122768263 ATP-dependent RNA helicase DDX19B\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"122777226 ddx19a; ATP-dependent RNA helicase DDX19A\tK18655 DDX19; ATP-dependent RNA helicase DDX19\/DBP5 [EC:5.6.2.7]" }, { "name":"122760715 xab2; pre-mRNA-splicing factor SYF1\tK12867 SYF1; pre-mRNA-splicing factor SYF1" }, { "name":"122776626 SAP domain-containing ribonucleoprotein\tK18732 SARNP; SAP domain-containing ribonucleoprotein" }, { "name":"122776698 SAP domain-containing ribonucleoprotein-like isoform X1\tK18732 SARNP; SAP domain-containing ribonucleoprotein" }, { "name":"122775267 rcc1; regulator of chromosome condensation\tK11493 RCC1; regulator of chromosome condensation" }, { "name":"122772822 larp6a; la-related protein 6a\tK18733 LARP6; la-related protein 6" }, { "name":"122778495 purab; transcriptional activator protein Pur-alpha\tK21772 PURA; transcriptional activator protein Pur-alpha" }, { "name":"122780083 puraa; purine-rich element binding protein Aa\tK21772 PURA; transcriptional activator protein Pur-alpha" }, { "name":"122758538 transcriptional activator protein Pur-beta\tK21799 PURB; transcriptional activator protein Pur-beta" }, { "name":"122769623 transcriptional activator protein Pur-beta-like\tK21799 PURB; transcriptional activator protein Pur-beta" }, { "name":"122785877 poldip3; polymerase delta-interacting protein 3\tK22414 POLDIP3; polymerase delta-interacting protein 3" }, { "name":"122768253 zc3h11a; zinc finger CCCH domain-containing protein 11A\tK22415 ZC3H11; zinc finger CCCH domain-containing protein 11" }, { "name":"122774360 leng8; leukocyte receptor cluster member 8 homolog\tK23802 LENG8; SAC3 family protein LENG8\/THP3" }, { "name":"122759469 patl2; protein PAT1 homolog 2\tK24823 PATL2; protein PAT1 homolog 2" }, { "name":"122767135 UAP56-interacting factor-like\tK28772 FYTTD1; UAP56-interacting factor" } ] } ] }, { "name":"Surveillance factors", "children":[ { "name":"Surveillance complex", "children":[ { "name":"122761673 eukaryotic peptide chain release factor subunit 1\tK03265 ETF1; peptide chain release factor subunit 1" }, { "name":"122759381 gspt1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"122784903 gspt1l; G1 to S phase transition 1, like\tK03267 ERF3; peptide chain release factor subunit 3" }, { "name":"122770534 regulator of nonsense transcripts 1-like\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122780615 upf1; regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122766639 upf2; regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"122765229 upf3a; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"122777969 upf3b; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3" } ] }, { "name":"Protein phosphatase 2A", "children":[ { "name":"122769700 serine\/threonine-protein phosphatase 2A catalytic subunit beta isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"122778823 serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform-like\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"122779991 ppp2cab; serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]" }, { "name":"122773647 serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A" }, { "name":"122768994 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122770784 ppp2r2ca; protein phosphatase 2, regulatory subunit B, gamma a\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122778392 ppp2r2ba; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122778482 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122781785 ppp2r2d; serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122787121 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform-like\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B" }, { "name":"122759145 ppp2r3b; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"122782788 ppp2r3a; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"122783394 ppp2r3c; serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''" }, { "name":"122766411 ppp2r5b; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"122781603 ppp2r5d; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"122782681 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"122782967 ppp2r5eb; protein phosphatase 2, regulatory subunit B', epsilon isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"122783636 ppp2r5cb; protein phosphatase 2, regulatory subunit B', gamma b isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" }, { "name":"122783760 ppp2r5a; serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'" } ] }, { "name":"Other surveillance factors", "children":[ { "name":"122785676 smg1; serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"122774594 smg5; protein SMG5\tK11125 SMG5; protein SMG5" }, { "name":"122779651 smg6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"122761324 smg7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"122779969 smg8; protein SMG8\tK18734 SMG8; protein SMG8" }, { "name":"122774555 smg9; protein SMG9 isoform X1\tK18735 SMG9; protein SMG9" }, { "name":"122766487 gigyf1a; GRB10-interacting GYF protein 1 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"122773497 gigyf2; GRB10-interacting GYF protein 2 isoform X1\tK18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein" }, { "name":"122769402 selenocysteine insertion sequence-binding protein 2-like\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2" }, { "name":"122772606 secisbp2l; LOW QUALITY PROTEIN: selenocysteine insertion sequence-binding protein 2-like\tK19539 SECISBP2; selenocysteine insertion sequence-binding protein 2" }, { "name":"122773415 dhx34; probable ATP-dependent RNA helicase DHX34\tK20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]" }, { "name":"122765401 GTP-binding protein 1-like\tK24887 GTPBP1; GTP-binding protein 1" }, { "name":"122771094 GTP-binding protein 1-like isoform X1\tK24887 GTPBP1; GTP-binding protein 1" }, { "name":"122785072 gtpbp1; GTP-binding protein 1 isoform X1\tK24887 GTPBP1; GTP-binding protein 1" } ] } ] }, { "name":"Factors involved in mRNA localization", "children":[ { "name":"Cargo complex", "children":[ { "name":"122762104 pum3; pumilio homolog 3\tK14844 PUF6; pumilio homology domain family member 6" }, { "name":"122758217 myo5b; unconventional myosin-Vb isoform X1\tK10357 MYO5; myosin V" }, { "name":"122772402 myo5aa; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"122775548 unconventional myosin-Va-like\tK10357 MYO5; myosin V" }, { "name":"122775549 myo5c; unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"122780988 si:dkey-110c1.10; unconventional myosin-Va\tK10357 MYO5; myosin V" }, { "name":"122767309 protein bicaudal D homolog 1-like isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"122767894 bicd2; protein bicaudal D homolog 2\tK18739 BICD; protein bicaudal D" }, { "name":"122775366 bicd1a; protein bicaudal D homolog 1 isoform X1\tK18739 BICD; protein bicaudal D" }, { "name":"122776892 zgc:162200; protein bicaudal D homolog 2\tK18739 BICD; protein bicaudal D" }, { "name":"122777148 protein bicaudal D homolog 2-like\tK18739 BICD; protein bicaudal D" } ] }, { "name":"Factors that have mRNA localization signals", "children":[ { "name":"122759849 actb2; actin, cytoplasmic 2\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"122769161 actin, non-muscle 6.2\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"122770925 actb1; actin, cytoplasmic 1\tK05692 ACTB_G1; actin beta\/gamma 1" }, { "name":"122786249 mbpa; myelin basic protein isoform X1\tK17269 MBP; myelin basic protein" }, { "name":"122778244 vimr2; low molecular weight neuronal intermediate filament\tK07606 VIM; vimentin" }, { "name":"122779592 vimentin A2-like\tK07606 VIM; vimentin" }, { "name":"122761011 mt2; metallothionein-2\tK14739 MT1_2; metallothionein 1\/2" }, { "name":"122765450 mycb; transcriptional regulator Myc-B isoform X1\tK04377 MYC; Myc proto-oncogene protein" }, { "name":"122768632 myca; transcriptional regulator Myc-A\tK04377 MYC; Myc proto-oncogene protein" }, { "name":"122758543 T-box-containing protein TBX6L-like\tK10180 TBX6; T-box protein 6" }, { "name":"122759484 tbx6; T-box transcription factor TBX6\tK10180 TBX6; T-box protein 6" }, { "name":"122769921 tbx16; T-box transcription factor 16\tK10180 TBX6; T-box protein 6" }, { "name":"122772954 uncharacterized protein LOC122772954 isoform X1\tK18741 NANOS1; protein nanos 1" }, { "name":"122778933 nanos1; nanos homolog 1\tK18741 NANOS1; protein nanos 1" }, { "name":"122783099 nanos homolog 1-like\tK18741 NANOS1; protein nanos 1" } ] }, { "name":"Trans-acting binding proteins", "children":[ { "name":"122758417 fubp3; far upstream element-binding protein 3\tK13210 FUBP; far upstream element-binding protein" }, { "name":"122769604 far upstream element-binding protein 3-like isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"122771250 fubp1; far upstream element-binding protein 1 isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"122771500 far upstream element-binding protein 2\tK13210 FUBP; far upstream element-binding protein" }, { "name":"122784850 far upstream element-binding protein 2-like isoform X1\tK13210 FUBP; far upstream element-binding protein" }, { "name":"122781602 si:dkey-37o8.1; elongation factor 1-alpha-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122781999 elongation factor 1-alpha 1\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122786270 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122786271 elongation factor 1-alpha\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122786605 elongation factor 1-alpha-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122786606 elongation factor 1-alpha-like\tK03231 EEF1A; elongation factor 1-alpha" }, { "name":"122778103 eef1g; elongation factor 1-gamma\tK03233 EEF1G; elongation factor 1-gamma" }, { "name":"122786944 hax1; HCLS1-associated protein X-1\tK16220 HAX1; HCLS1-associated protein X-1" }, { "name":"122766370 agfg2; arf-GAP domain and FG repeat-containing protein 2 isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"122773335 agfg1a; arf-GAP domain and FG repeat-containing protein 1a isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"122777153 agfg1b; arf-GAP domain and FG repeat-containing protein 1b isoform X1\tK15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1" }, { "name":"122768308 stau1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"122771905 stau2; double-stranded RNA-binding protein Staufen homolog 2\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"122760168 igf2bp3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1\tK13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3" }, { "name":"122780656 ptbp1b; polypyrimidine tract-binding protein 1b isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"122782891 ptbp1a; polypyrimidine tract-binding protein 1a isoform X1\tK13218 PTBP1; polypyrimidine tract-binding protein 1" }, { "name":"122772498 cpeb1b; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122778525 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122779448 cpeb4b; cytoplasmic polyadenylation element-binding protein 4b isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122781049 cpeb2; cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122782128 cpeb3; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" } ] }, { "name":"Other mRNA localization factors", "children":[ { "name":"122765791 fxr2; fragile X mental retardation syndrome-related protein 2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122778452 fmr1; synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122780770 fxr1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122759900 cyfip1; cytoplasmic FMR1-interacting protein 1 homolog\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"122778396 cyfip2; cytoplasmic FMR1-interacting protein 2 isoform X1\tK05749 CYFIP; cytoplasmic FMR1 interacting protein" }, { "name":"122767611 poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"122777160 poly(rC)-binding protein 2-like isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"122765271 pcbp3; poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"122765605 poly(rC)-binding protein 3-like isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"122768000 poly(rC)-binding protein 4-like isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"122777428 poly(rC)-binding protein 4-like\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"122782116 zgc:110045; poly(rC)-binding protein 3 isoform X1\tK21444 PCBP3_4; poly(rC)-binding protein 3\/4" }, { "name":"122760236 caprin-1-like isoform X1\tK18743 CAPRIN1; caprin-1" }, { "name":"122775893 caprin1b; caprin-1b isoform X1\tK18743 CAPRIN1; caprin-1" }, { "name":"122765762 caprin2; caprin-2 isoform X1\tK18744 CAPRIN2; caprin-2" }, { "name":"122776942 ybx1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1" } ] } ] }, { "name":"mRNA cycle factors", "children":[ { "name":"Common to processing body (P body) and stress granule", "children":[ { "name":"122766761 xrn1; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"122760165 ago2; protein argonaute-2 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"122760298 protein argonaute-3\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"122775124 ago1; protein argonaute-1 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"122786110 ago4; protein argonaute-4 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"122786199 ago3b; protein argonaute-3 isoform X1\tK11593 ELF2C; eukaryotic translation initiation factor 2C" }, { "name":"122770821 eif4e2; eukaryotic translation initiation factor 4E type 2 isoform X1\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122778175 eukaryotic translation initiation factor 4E-1A-like\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122782326 eif4e1c; eukaryotic translation initiation factor 4E family member 1c\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122782412 eif4eb; eukaryotic translation initiation factor 4eb\tK03259 EIF4E; translation initiation factor 4E" }, { "name":"122770534 regulator of nonsense transcripts 1-like\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122780615 upf1; regulator of nonsense transcripts 1 isoform X1\tK14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122762895 putative ATP-dependent RNA helicase an3 isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"122785191 ATP-dependent RNA helicase DDX3X-like isoform X1\tK11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]" }, { "name":"122759882 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122773408 ddx6; probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122786215 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122769854 RNA-binding protein MEX3B-like\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"122772661 mex3b; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"122775040 mex3a; RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"122775588 RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]" }, { "name":"122775989 fastk; fas-activated serine\/threonine kinase\tK08290 FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]" }, { "name":"122767563 protein LSM14 homolog B-like\tK18749 LSM14; protein LSM14" }, { "name":"122772458 lsm14ab; LSM14A mRNA processing body assembly factor b isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"122775399 lsm14aa; LSM14A mRNA processing body assembly factor a\tK18749 LSM14; protein LSM14" }, { "name":"122777656 lsm14b; protein LSM14 homolog B isoform X1\tK18749 LSM14; protein LSM14" }, { "name":"122767611 poly(rC)-binding protein 2 isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"122777160 poly(rC)-binding protein 2-like isoform X1\tK13162 PCBP2; poly(rC)-binding protein 2" }, { "name":"122776942 ybx1; Y-box-binding protein 1 isoform X1\tK09276 YBX1; Y-box-binding protein 1" }, { "name":"122766141 ajuba; LIM domain-containing protein ajuba\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"122772481 Wilms tumor protein 1-interacting protein homolog\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"122774260 LIM domain-containing protein 1\tK16682 AJUBA; LIM domain-containing protein" }, { "name":"122768852 mov10a; putative helicase mov-10-B.1\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]" }, { "name":"122770123 putative helicase mov-10-B.2\tK18422 MOV10; helicase MOV-10 [EC:5.6.2.5]" }, { "name":"122774510 pnrc2; proline-rich nuclear receptor coactivator 2\tK18751 PNRC2; proline-rich nuclear receptor coactivator 2" }, { "name":"122758182 tnpo1; transportin-1\tK18752 TNPO1; transportin-1" }, { "name":"122785676 smg1; serine\/threonine-protein kinase SMG1 isoform X1\tK08873 SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]" }, { "name":"122774594 smg5; protein SMG5\tK11125 SMG5; protein SMG5" }, { "name":"122779651 smg6; telomerase-binding protein EST1A isoform X1\tK11124 SMG6; protein SMG6 [EC:3.1.-.-]" }, { "name":"122761324 smg7; protein SMG7 isoform X1\tK14409 SMG7; protein SMG7" }, { "name":"122773738 mRNA decay activator protein ZFP36L1\tK18753 ZFP36L; butyrate response factor" }, { "name":"122774008 zgc:114130; mRNA decay activator protein ZFP36L1\tK18753 ZFP36L; butyrate response factor" }, { "name":"122782183 zfp36l2; mRNA decay activator protein ZFP36L2 isoform X1\tK18753 ZFP36L; butyrate response factor" }, { "name":"122782586 zfp36l1a; mRNA decay activator protein ZFP36L1a\tK18753 ZFP36L; butyrate response factor" }, { "name":"122783673 mRNA decay activator protein ZFP36L1-like\tK18753 ZFP36L; butyrate response factor" }, { "name":"122760440 protein lin-28 homolog B-like\tK18754 LIN28; protein lin-28" }, { "name":"122774712 lin28aa; protein lin-28 homolog A isoform X1\tK18754 LIN28; protein lin-28" }, { "name":"122778809 protein lin-28 homolog B-like\tK18754 LIN28; protein lin-28" }, { "name":"122786773 protein lin-28 homolog A-like\tK18754 LIN28; protein lin-28" }, { "name":"122770715 htt; huntingtin isoform X1\tK04533 HD; huntingtin" }, { "name":"122766745 ipo8; importin-8 isoform X1\tK18755 IPO8; importin-8" }, { "name":"122778425 bicc2; bicaudal C homolog 2\tK18756 BICC1; protein bicaudal C" }, { "name":"122782240 protein bicaudal C homolog 1-like\tK18756 BICC1; protein bicaudal C" }, { "name":"122776975 hnrnpa1b; heterogeneous nuclear ribonucleoprotein A1b isoform X1\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"122786686 hnrnpa3; heterogeneous nuclear ribonucleoprotein A3\tK12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1\/A3" }, { "name":"122771368 prkacab; cAMP-dependent protein kinase catalytic subunit alpha\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"122772674 prkacbb; protein kinase, cAMP-dependent, catalytic, beta b isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"122780814 prkacba; protein kinase, cAMP-dependent, catalytic, beta a isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"122785644 prkacaa; protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a isoform X1\tK04345 PKA; protein kinase A [EC:2.7.11.11]" }, { "name":"122779490 larp1; la-related protein 1 isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"122782927 larp1b; la-related protein 1B isoform X1\tK18757 LARP1; la-related protein 1" }, { "name":"122759590 atxn2l; ataxin-2-like protein\tK23625 ATXN2; ataxin-2" }, { "name":"122769472 atxn2; ataxin-2 isoform X1\tK23625 ATXN2; ataxin-2" } ] }, { "name":"P-body specific factors", "children":[ { "name":"122758692 dcp2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"122777144 dcp1a; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"122767005 dcp1b; mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"122769987 lsm1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"122780444 smx5; smx5\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"122767705 lsm3; snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"122780412 lsm4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"122775128 lsm5; U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"122770443 lsm6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"122780955 lsm7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"122761037 lsm8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" }, { "name":"122766466 klc2; kinesin light chain 2\tK10407 KLC; kinesin light chain" }, { "name":"122773543 kinesin light chain 1-like\tK10407 KLC; kinesin light chain" }, { "name":"122781583 klc1b; kinesin light chain 1b isoform X1\tK10407 KLC; kinesin light chain" }, { "name":"122782518 klc1a; LOW QUALITY PROTEIN: kinesin light chain 1\tK10407 KLC; kinesin light chain" }, { "name":"122758217 myo5b; unconventional myosin-Vb isoform X1\tK10357 MYO5; myosin V" }, { "name":"122772402 myo5aa; unconventional myosin-Va isoform X1\tK10357 MYO5; myosin V" }, { "name":"122775548 unconventional myosin-Va-like\tK10357 MYO5; myosin V" }, { "name":"122775549 myo5c; unconventional myosin-Vc\tK10357 MYO5; myosin V" }, { "name":"122780988 si:dkey-110c1.10; unconventional myosin-Va\tK10357 MYO5; myosin V" }, { "name":"122758068 tubulin alpha-1B chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122758957 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122760595 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122761255 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122761642 tubulin alpha-1C chain-like isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"122761643 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122761649 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122764898 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122765523 tubulin alpha chain\tK07374 TUBA; tubulin alpha" }, { "name":"122765524 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122765599 tubulin alpha-1A chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122776719 tubulin alpha-1C chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122776901 tuba5; tubulin alpha 5\tK07374 TUBA; tubulin alpha" }, { "name":"122776957 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122777619 tubulin alpha chain\tK07374 TUBA; tubulin alpha" }, { "name":"122777899 tuba1a; tubulin alpha-1A chain\tK07374 TUBA; tubulin alpha" }, { "name":"122777900 tubulin alpha chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122784312 tubulin alpha chain-like isoform X1\tK07374 TUBA; tubulin alpha" }, { "name":"122787007 tubulin alpha-1B chain-like\tK07374 TUBA; tubulin alpha" }, { "name":"122772498 cpeb1b; cytoplasmic polyadenylation element-binding protein 1 isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122778525 cytoplasmic polyadenylation element-binding protein 4-like isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122779448 cpeb4b; cytoplasmic polyadenylation element-binding protein 4b isoform X1\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122781049 cpeb2; cytoplasmic polyadenylation element-binding protein 2\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122782128 cpeb3; LOW QUALITY PROTEIN: cytoplasmic polyadenylation element-binding protein 3\tK02602 CPEB; cytoplasmic polyadenylation element-binding protein" }, { "name":"122779992 gemin5; gem-associated protein 5\tK13133 GEMIN5; gem associated protein 5" }, { "name":"122783075 tacc3; transforming acidic coiled-coil-containing protein 3\tK14283 TACC3; transforming acidic coiled-coil-containing protein 3" }, { "name":"122758971 tnrc6ba; LOW QUALITY PROTEIN: trinucleotide repeat-containing gene 6B protein\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"122760638 tnrc6c1; trinucleotide repeat-containing gene 6C protein\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"122771209 tnrc6c2; trinucleotide repeat-containing gene 6C protein isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"122785197 trinucleotide repeat-containing gene 6B protein-like isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"122785874 trinucleotide repeat-containing gene 6A protein-like isoform X1\tK18412 TNRC6; trinucleotide repeat-containing gene 6 protein" }, { "name":"122775572 cnot1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"122766312 CCR4-NOT transcription complex subunit 2-like isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"122775639 cnot2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"122774531 cnot3a; CCR4-NOT transcription complex subunit 3a isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"122786507 CCR4-NOT transcription complex subunit 3-like\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"122776050 cnot4a; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"122769894 cnot6l; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"122778391 cnot6a; CCR4-NOT transcription complex subunit 6a\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"122778134 cnot7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122779994 cnot8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122782233 CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122772456 granule associated Rac and RHOG effector protein 1-like\tK26671 GARRE1; granule associated Rac and RHOG effector protein 1" }, { "name":"122777804 dis3l2; DIS3-like exonuclease 2\tK18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]" }, { "name":"122777043 pan2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"122774015 pan3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" }, { "name":"122759677 tob1b; protein Tob1b\tK14443 TOB; protein Tob\/BTG" }, { "name":"122762736 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122765431 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122766613 btg1; protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"122774567 si:dkey-79d12.5; protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"122779582 btg4; protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"122779775 btg3; protein BTG3\tK14443 TOB; protein Tob\/BTG" }, { "name":"122783776 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122784499 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122785642 protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"122785745 protein Tob1-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122768063 eif4enif1; eukaryotic translation initiation factor 4E transporter\tK18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter" }, { "name":"122771281 patl1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" }, { "name":"122760727 edc3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"122775714 edc4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"122771081 nanos3; nanos homolog 3\tK18761 NANOS3; protein nanos 3" }, { "name":"122766639 upf2; regulator of nonsense transcripts 2 isoform X1\tK14327 UPF2; regulator of nonsense transcripts 2" }, { "name":"122765229 upf3a; regulator of nonsense transcripts 3A isoform X1\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"122777969 upf3b; regulator of nonsense transcripts 3B\tK14328 UPF3; regulator of nonsense transcripts 3" }, { "name":"122786631 trim71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]" }, { "name":"122778105 polr2g; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7" }, { "name":"122781705 eif2ak2; interferon-induced, double-stranded RNA-activated protein kinase\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"122781707 interferon-induced, double-stranded RNA-activated protein kinase-like\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"122781708 interferon-induced, double-stranded RNA-activated protein kinase-like\tK16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]" }, { "name":"122780104 zar1l; ZAR1-like protein\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"122781123 zar1; zygote arrest protein 1\tK18762 ZAR1; zygote arrest protein 1" }, { "name":"122760537 ythdf1; YTH domain-containing family protein 1\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"122776248 ythdf3; YTH domain-containing family protein 3\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"122777018 YTH domain-containing family protein 1-like\tK20102 YTHDF; YTH domain-containing family protein" }, { "name":"122783208 ythdf2; YTH domain-containing family protein 2\tK20102 YTHDF; YTH domain-containing family protein" } ] }, { "name":"Stress granule specific factors", "children":[ { "name":"122758178 tia1; nucleolysin TIA-1 isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"122769646 nucleolysin TIA-1-like\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"122781717 tial1; nucleolysin TIAR isoform X1\tK13201 TIA1; nucleolysin TIA-1\/TIAR" }, { "name":"122761256 pabpc4; polyadenylate-binding protein 4 isoform X1\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122774764 polyadenylate-binding protein 1A\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122786804 polyadenylate-binding protein 1-like\tK13126 PABPC; polyadenylate-binding protein" }, { "name":"122768308 stau1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"122771905 stau2; double-stranded RNA-binding protein Staufen homolog 2\tK17597 STAU; double-stranded RNA-binding protein Staufen" }, { "name":"122765791 fxr2; fragile X mental retardation syndrome-related protein 2 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122778452 fmr1; synaptic functional regulator FMR1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122780770 fxr1; fragile X mental retardation syndrome-related protein 1 isoform X1\tK15516 FMR; fragile X mental retardation protein" }, { "name":"122780520 ELAV-like protein 1 isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"122782645 elavl1a; ELAV-like protein 1a isoform X1\tK13088 ELAVL1; ELAV-like protein 1" }, { "name":"122778694 ras GTPase-activating protein-binding protein 1-like\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122778843 ras GTPase-activating protein-binding protein 1-like\tK17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]" }, { "name":"122770830 g3bp2a; ras GTPase-activating protein-binding protein 2 isoform X1\tK24983 G3BP2; Ras GTPase-activating protein-binding protein 2" }, { "name":"122773550 eif2a; eukaryotic translation initiation factor 2A\tK15026 EIF2A; translation initiation factor 2A" }, { "name":"122770790 eif3ba; eukaryotic translation initiation factor 3, subunit Ba\tK03253 EIF3B; translation initiation factor 3 subunit B" }, { "name":"122767130 eif4a1a; eukaryotic translation initiation factor 4A1A\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122768810 eif4a2; eukaryotic initiation factor 4A-II\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122781812 eukaryotic initiation factor 4A-II-like\tK03257 EIF4A; translation initiation factor 4A" }, { "name":"122770582 eif4a3; eukaryotic initiation factor 4A-III\tK13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]" }, { "name":"122775580 eif4ba; eukaryotic translation initiation factor 4Ba isoform X1\tK03258 EIF4B; translation initiation factor 4B" }, { "name":"122767593 eif4g1a; eukaryotic translation initiation factor 4 gamma 1a isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122768420 eif4g3a; eukaryotic translation initiation factor 4 gamma 3\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122772487 eif4g2a; eukaryotic translation initiation factor 4 gamma 2a\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122773276 eukaryotic translation initiation factor 4 gamma 1-like isoform X1\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122775851 eif4g2b; eukaryotic translation initiation factor 4 gamma 2b\tK03260 EIF4G; translation initiation factor 4G" }, { "name":"122761345 ribosomal protein S6 kinase alpha-1-like isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"122772036 rps6ka3b; ribosomal protein S6 kinase alpha-3\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"122772729 rps6ka2; ribosomal protein S6 kinase alpha-2 isoform X1\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"122778271 rps6kal; ribosomal protein S6 kinase alpha-6\tK04373 RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]" }, { "name":"122778604 rack1; guanine nucleotide-binding protein subunit beta-2-like 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein" }, { "name":"122758001 traf2b; TNF receptor-associated factor 2\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"122758611 TNF receptor-associated factor 2-like\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"122769977 TNF receptor-associated factor 2-like isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]" }, { "name":"122778964 nxf1a; nuclear RNA export factor 1 isoform X1\tK14284 NXF; nuclear RNA export factor" }, { "name":"122776869 hdac6; histone deacetylase 6\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]" }, { "name":"122772806 tdrd3; tudor domain-containing protein 3 isoform X1\tK18404 TDRD3; tudor domain-containing protein 3" }, { "name":"122768238 larp4ab; la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4" }, { "name":"122769228 uncharacterized protein LOC122769228\tK18763 LARP4; la-related protein 4" }, { "name":"122774998 la-related protein 4B-like isoform X1\tK18763 LARP4; la-related protein 4" }, { "name":"122777078 la-related protein 4 isoform X1\tK18763 LARP4; la-related protein 4" } ] } ] } ] }, { "name":"mRNA degradation factors", "children":[ { "name":"5'-3' decay", "children":[ { "name":"Decapping complex", "children":[ { "name":"122777144 dcp1a; mRNA-decapping enzyme 1A\tK12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]" }, { "name":"122767005 dcp1b; mRNA-decapping enzyme 1B\tK12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]" }, { "name":"122758692 dcp2; m7GpppN-mRNA hydrolase\tK12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]" }, { "name":"122759882 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122773408 ddx6; probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122786215 probable ATP-dependent RNA helicase ddx6\tK12614 DDX6; ATP-dependent RNA helicase DDX6\/DHH1 [EC:5.6.2.7]" }, { "name":"122760727 edc3; enhancer of mRNA-decapping protein 3\tK12615 EDC3; enhancer of mRNA-decapping protein 3" }, { "name":"122775714 edc4; enhancer of mRNA-decapping protein 4\tK12616 EDC4; enhancer of mRNA-decapping protein 4" }, { "name":"122771281 patl1; protein PAT1 homolog 1\tK12617 PATL1; DNA topoisomerase 2-associated protein PAT1" } ] }, { "name":"Lsm complex", "children":[ { "name":"122769987 lsm1; U6 snRNA-associated Sm-like protein LSm1\tK12620 LSM1; U6 snRNA-associated Sm-like protein LSm1" }, { "name":"122780444 smx5; smx5\tK12621 LSM2; U6 snRNA-associated Sm-like protein LSm2" }, { "name":"122767705 lsm3; snRNA-associated Sm-like protein LSm3\tK12622 LSM3; U6 snRNA-associated Sm-like protein LSm3" }, { "name":"122780412 lsm4; U6 snRNA-associated Sm-like protein LSm4\tK12623 LSM4; U6 snRNA-associated Sm-like protein LSm4" }, { "name":"122775128 lsm5; U6 snRNA-associated Sm-like protein LSm5\tK12624 LSM5; U6 snRNA-associated Sm-like protein LSm5" }, { "name":"122770443 lsm6; U6 snRNA-associated Sm-like protein LSm6\tK12625 LSM6; U6 snRNA-associated Sm-like protein LSm6" }, { "name":"122780955 lsm7; U6 snRNA-associated Sm-like protein LSm7\tK12626 LSM7; U6 snRNA-associated Sm-like protein LSm7" }, { "name":"122761037 lsm8; LSM8 homolog, U6 small nuclear RNA associated\tK12627 LSM8; U6 snRNA-associated Sm-like protein LSm8" } ] }, { "name":"5' exonucleases", "children":[ { "name":"122766761 xrn1; 5'-3' exoribonuclease 1\tK12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]" }, { "name":"122784340 xrn2; 5'-3' exoribonuclease 2 isoform X1\tK12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]" }, { "name":"122776679 zgc:103759; U8 snoRNA-decapping enzyme isoform X1\tK16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]" } ] }, { "name":"Other 5'-3' decay factors", "children":[ { "name":"122761366 m7GpppX diphosphatase-like\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"122778794 m7GpppX diphosphatase-like\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"122770952 helz; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" } ] } ] }, { "name":"3'-5' decay", "children":[ { "name":"Core exosome factors", "children":[ { "name":"122771449 exosc1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4" }, { "name":"122758243 exosc2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"122778198 exosc3; exosome complex component RRP40\tK03681 RRP40; exosome complex component RRP40" }, { "name":"122775824 exosc4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"122772964 exosc5; exosome complex component RRP46\tK12590 RRP46; exosome complex component RRP46" }, { "name":"122775692 exosc6; exosome complex component MTR3\tK12587 MTR3; exosome complex component MTR3" }, { "name":"122760311 exosome complex component RRP42-like\tK12589 RRP42; exosome complex component RRP42" }, { "name":"122786541 exosome complex component RRP42-like\tK12589 RRP42; exosome complex component RRP42" }, { "name":"122779619 exosome complex component RRP43-like\tK12586 RRP43; exosome complex component RRP43" }, { "name":"122779779 exosome complex component RRP43-like\tK12586 RRP43; exosome complex component RRP43" }, { "name":"122770555 exosc9; exosome complex component RRP45\tK03678 RRP45; exosome complex component RRP45" } ] }, { "name":"Exosome cofactors", "children":[ { "name":"122781869 dis3; exosome complex exonuclease RRP44\tK12585 DIS3; exosome complex exonuclease DIS3\/RRP44 [EC:3.1.13.-]" }, { "name":"122772547 dis3l; DIS3-like exonuclease 1\tK18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]" }, { "name":"122777719 exosc10; exosome component 10\tK12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]" }, { "name":"122782325 c1d; nuclear nucleic acid-binding protein C1D\tK12592 C1D; exosome complex protein LRP1" }, { "name":"122775402 mphosph6; M-phase phosphoprotein 6\tK12593 MPHOSPH6; M-phase phosphoprotein 6, animal type" } ] }, { "name":"TRAMP complex", "children":[ { "name":"122772188 tent4b; terminal nucleotidyltransferase 4B\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"122774442 terminal nucleotidyltransferase 4A-like isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"122786012 tent4a; terminal nucleotidyltransferase 4A isoform X1\tK03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]" }, { "name":"122771340 zcchc7; zinc finger CCHC domain-containing protein 7\tK12597 AIR1_2; protein AIR1\/2" }, { "name":"122778300 zinc finger CCHC domain-containing protein 7-like isoform X1\tK12597 AIR1_2; protein AIR1\/2" }, { "name":"122758410 mtrex; exosome RNA helicase MTR4\tK12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]" } ] }, { "name":"Ski complex", "children":[ { "name":"122786634 skiv2l; helicase SKI2W\tK12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]" }, { "name":"122769371 ttc37; tetratricopeptide repeat protein 37\tK12600 SKI3; superkiller protein 3" }, { "name":"122776147 wdr61; WD repeat-containing protein 61\tK12602 WDR61; WD repeat-containing protein 61" } ] }, { "name":"Ccr4-NOT complex", "children":[ { "name":"122769894 cnot6l; CCR4-NOT transcription complex subunit 6-like\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"122778391 cnot6a; CCR4-NOT transcription complex subunit 6a\tK12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]" }, { "name":"122775572 cnot1; CCR4-NOT transcription complex subunit 1 isoform X1\tK12604 CNOT1; CCR4-NOT transcription complex subunit 1" }, { "name":"122766312 CCR4-NOT transcription complex subunit 2-like isoform X1\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"122775639 cnot2; CCR4-NOT transcription complex subunit 2\tK12605 CNOT2; CCR4-NOT transcription complex subunit 2" }, { "name":"122774531 cnot3a; CCR4-NOT transcription complex subunit 3a isoform X1\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"122786507 CCR4-NOT transcription complex subunit 3-like\tK12580 CNOT3; CCR4-NOT transcription complex subunit 3" }, { "name":"122776050 cnot4a; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]" }, { "name":"122778134 cnot7; CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122779994 cnot8; CCR4-NOT transcription complex subunit 8\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122782233 CCR4-NOT transcription complex subunit 7\tK12581 CNOT7_8; CCR4-NOT transcription complex subunit 7\/8" }, { "name":"122759045 cnot9; CCR4-NOT transcription complex subunit 9\tK12606 RCD1; CCR4-NOT transcription complex subunit 9" }, { "name":"122762540 cnot10; CCR4-NOT transcription complex subunit 10 isoform X1\tK12607 CNOT10; CCR4-NOT transcription complex subunit 10" } ] }, { "name":"Pan complex", "children":[ { "name":"122777043 pan2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1\tK12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]" }, { "name":"122774015 pan3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1\tK12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3" } ] }, { "name":"Other 3'-5' decay factors", "children":[ { "name":"122771581 parn; poly(A)-specific ribonuclease PARN\tK01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]" }, { "name":"122773793 dhx36; ATP-dependent DNA\/RNA helicase DHX36\tK14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]" }, { "name":"122759677 tob1b; protein Tob1b\tK14443 TOB; protein Tob\/BTG" }, { "name":"122762736 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122765431 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122766613 btg1; protein BTG1\tK14443 TOB; protein Tob\/BTG" }, { "name":"122774567 si:dkey-79d12.5; protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"122779582 btg4; protein BTG4\tK14443 TOB; protein Tob\/BTG" }, { "name":"122779775 btg3; protein BTG3\tK14443 TOB; protein Tob\/BTG" }, { "name":"122783776 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122784499 protein BTG3-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122785642 protein Tob2\tK14443 TOB; protein Tob\/BTG" }, { "name":"122785745 protein Tob1-like\tK14443 TOB; protein Tob\/BTG" }, { "name":"122762066 noctb; nocturnin\tK18764 NOCT; nocturnin [EC:3.1.3.108]" }, { "name":"122778975 nocturnin-like\tK18764 NOCT; nocturnin [EC:3.1.3.108]" }, { "name":"122766588 eri1; 3'-5' exoribonuclease 1\tK18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]" }, { "name":"122771466 eri2; ERI1 exoribonuclease 2\tK18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]" }, { "name":"122761366 m7GpppX diphosphatase-like\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"122778794 m7GpppX diphosphatase-like\tK12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]" }, { "name":"122767857 pde12; 2',5'-phosphodiesterase 12\tK19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]" }, { "name":"122775540 ireb2; iron-responsive element-binding protein 2\tK22416 IREB2; iron-responsive element-binding protein 2" }, { "name":"122770952 helz; probable helicase with zinc finger domain\tK25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]" }, { "name":"122768418 helz2a; helicase with zinc finger domain 2\tK25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]" }, { "name":"122783292 nrde2; nuclear exosome regulator NRDE2 isoform X1\tK26109 NRDE2; nuclear exosome regulator NRDE2" }, { "name":"122772164 samd4a; protein Smaug homolog 1 isoform X1\tK27396 SMG; protein Smaug" }, { "name":"122773882 protein Smaug homolog 2\tK27396 SMG; protein Smaug" }, { "name":"122766857 focad; focadhesin\tK27498 FOCAD; focadhesin" } ] } ] }, { "name":"Other degradation factors", "children":[ { "name":"RNases", "children":[ { "name":"122765035 probable ribonuclease ZC3H12C\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"122771131 zc3h12b; probable ribonuclease ZC3H12B\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" }, { "name":"122775301 endoribonuclease ZC3H12A\tK18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]" } ] } ] } ] } ] }, { "name":"Prokaryotic type", "children":[ { "name":"Bacterial mRNA degradation factors", "children":[ { "name":"RNA degradosome components", "children":[ { "name":"Ribonucreases", "children":[ { "name":"122769513 drosha; ribonuclease 3\tK03685 rnc; ribonuclease III [EC:3.1.26.3]" }, { "name":"122779222 smfn; small fragment nuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]" } ] }, { "name":"Helicases" }, { "name":"Other RNA degradosome components", "children":[ { "name":"122766057 eno3; beta-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"122768192 eno1b; enolase 1b, (alpha)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"122775229 gamma-enolase-like isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"122777438 eno1a; enolase 1a, (alpha) isoform X1\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"122786657 gamma-enolase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]" }, { "name":"122781435 polyribonucleotide nucleotidyltransferase 1, mitochondrial\tK00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]" }, { "name":"122765084 pfkla; ATP-dependent 6-phosphofructokinase, liver type\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"122765097 pfkpa; ATP-dependent 6-phosphofructokinase, platelet type isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"122768259 pfkmb; phosphofructokinase, muscle b\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"122770465 ATP-dependent 6-phosphofructokinase, platelet type-like isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" }, { "name":"122777079 ATP-dependent 6-phosphofructokinase, muscle type-like\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]" } ] } ] }, { "name":"Other RNA degradation factors", "children":[ { "name":"Chaperones", "children":[ { "name":"122759037 hspa9; stress-70 protein, mitochondrial\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"122770957 stress-70 protein, mitochondrial-like\tK04043 dnaK; molecular chaperone DnaK" }, { "name":"122785060 hspd1; 60 kDa heat shock protein, mitochondrial\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]" } ] }, { "name":"Others" }, { "name":"Bacterial Small RNA Regulators" } ] } ] }, { "name":"Archeal mRNA degradation factors", "children":[ { "name":"Exosome components", "children":[ { "name":"Core exosome", "children":[ { "name":"122758243 exosc2; exosome complex component RRP4\tK03679 RRP4; exosome complex component RRP4" }, { "name":"122771449 exosc1; exosome complex component CSL4 isoform X1\tK07573 CSL4; exosome complex component CSL4" } ] }, { "name":"Cofactors", "children":[ { "name":"122775824 exosc4; exosome complex component RRP41\tK11600 RRP41; exosome complex component RRP41" }, { "name":"122760311 exosome complex component RRP42-like\tK12589 RRP42; exosome complex component RRP42" }, { "name":"122786541 exosome complex component RRP42-like\tK12589 RRP42; exosome complex component RRP42" } ] }, { "name":"Others" } ] } ] } ] } ] }