{
	"name":"strw03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"QHG49_10725 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"QHG49_22270 orn; (GenBank) oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins",
				"children":[
				{
					"name":"QHG49_13545 GNAT family N-acetyltransferase\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				}
				]
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"QHG49_23590 era; (GenBank) GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"QHG49_23295 obgE; (GenBank) GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"QHG49_25790 TraR\/DksA C4-type zinc finger protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"QHG49_10165 nusA; (GenBank) transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"QHG49_28760 nusB; (GenBank) transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"QHG49_14765 nusG; (GenBank) transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"QHG49_20545 rsmA; (GenBank) 16S rRNA (adenine(1518)-N(6)\/adenine(1519)-N(6))-dimethyltransferase RsmA\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"QHG49_28860 transcription antitermination factor NusB\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"QHG49_10750 rsmD; (GenBank) 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"QHG49_23490 16S rRNA (uracil(1498)-N(3))-methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"QHG49_17655 rsmG; (GenBank) 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"QHG49_25705 rsmH; (GenBank) 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"QHG49_20525 rsmI; (GenBank) 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"QHG49_27270 TlyA family RNA methyltransferase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"QHG49_19265 rlmB; (GenBank) 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"QHG49_30995 methyltransferase\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"QHG49_10500 rlmN; (GenBank) 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"QHG49_27270 TlyA family RNA methyltransferase\tK06442 tlyA; 23S rRNA (cytidine1920-2'-O)\/16S rRNA (cytidine1409-2'-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]"
				},
				{
					"name":"QHG49_28065 pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"QHG49_27350 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"QHG49_25800 RluA family pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"QHG49_14430 rimI; (GenBank) ribosomal protein S18-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"QHG49_06855 GNAT family N-acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"QHG49_18045 GNAT family protein\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"QHG49_20385 GNAT family protein\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"QHG49_11125 GNAT family protein\tK03817 rimL; ribosomal-protein-serine acetyltransferase [EC:2.3.1.-]"
			},
			{
				"name":"QHG49_10605 rimM; (GenBank) ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"QHG49_09960 rimO; (GenBank) 30S ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"QHG49_05915 TOMM precursor leader peptide-binding protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			},
			{
				"name":"QHG49_05945 TOMM precursor leader peptide-binding protein\tK09136 ycaO; ribosomal protein S12 methylthiotransferase accessory factor"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"QHG49_10725 rnc; (GenBank) ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"QHG49_23270 Rne\/Rng family ribonuclease\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"QHG49_28715 ruvX; (GenBank) Holliday junction resolvase RuvX\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases"
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"QHG49_23590 era; (GenBank) GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"QHG49_07835 rsgA; (GenBank) ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"QHG49_12515 rsgA; (GenBank) ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"QHG49_27395 der; (GenBank) ribosome biogenesis GTPase Der\tK03977 engA; GTPase"
			},
			{
				"name":"QHG49_23295 obgE; (GenBank) GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"QHG49_09725 hflX; (GenBank) GTPase HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"QHG49_11825 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"QHG49_33040 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"QHG49_33750 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"QHG49_09735 HD domain-containing protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"QHG49_28655 RelA\/SpoT family protein\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"QHG49_10145 rbfA; (GenBank) 30S ribosome-binding factor RbfA\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"QHG49_10170 rimP; (GenBank) ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"QHG49_23360 rsfS; (GenBank) ribosome silencing factor\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"QHG49_23540 ybeY; (GenBank) rRNA maturation RNase YbeY\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"QHG49_13150 ychF; (GenBank) redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"QHG49_10735 DUF177 domain-containing protein\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}
