{
	"name":"sty01011",
	"children":[
	{
		"name":"Precursor biosynthesis",
		"children":[
		{
			"name":"Transferase\/Dehydrogenase",
			"children":[
			{
				"name":"STY3486 UDP-N-acetylglucosamine 1-carboxyvinyltransferase\tK00790 murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]"
			},
			{
				"name":"STY3742 UDP-N-acetylenolpyruvoylglucosamine reductase\tK00075 murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]"
			}
			]
		},
		{
			"name":"Amino acid ligase",
			"children":[
			{
				"name":"STY0149 UDP-N-acetylmuramate:alanine ligase\tK01924 murC; UDP-N-acetylmuramate--alanine ligase [EC:6.3.2.8]"
			},
			{
				"name":"STY0146 UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase\tK01925 murD; UDP-N-acetylmuramoylalanine--D-glutamate ligase [EC:6.3.2.9]"
			},
			{
				"name":"STY0143 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-dia minopim ligase\tK01928 murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:6.3.2.13]"
			},
			{
				"name":"STY0150 D-alanine:D-alanine ligase B\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			},
			{
				"name":"STY0412 D-alanine:D-alanine ligase A\tK01921 ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]"
			}
			]
		},
		{
			"name":"Racemase",
			"children":[
			{
				"name":"STY1930 alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"STY3763 alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"STY4443 alr; alanine racemase\tK01775 alr; alanine racemase [EC:5.1.1.1]"
			},
			{
				"name":"STY3743 glutamate racemase\tK01776 murI; glutamate racemase [EC:5.1.1.3]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"STY1928 conserved hypothetical protein\tK01297 ldcA; muramoyltetrapeptide carboxypeptidase [EC:3.4.17.13]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"STY0145 phospho-N-acetylmuramoyl-pentapeptide-transferase\tK01000 mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]"
			},
			{
				"name":"STY0148 UDP-N-acetylglucosamine:N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase\tK02563 murG; UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]"
			}
			]
		},
		{
			"name":"Diphosphatase",
			"children":[
			{
				"name":"STY3384 bacitracin resistance protein (putative undecaprenol kinase)\tK06153 bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			},
			{
				"name":"STY0898 ybjG; putative permease protein\tK19302 bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]"
			}
			]
		},
		{
			"name":"Flippase",
			"children":[
			{
				"name":"STY1209 mviN; virulence factor MviN\tK03980 murJ; putative peptidoglycan lipid II flippase"
			}
			]
		}
		]
	},
	{
		"name":"Peptidoglycan biosynthesis and degradation",
		"children":[
		{
			"name":"Glycosyltransferase\/DD-Transpeptidase (Class A PBP)",
			"children":[
			{
				"name":"STY4303 mrcA; penicillin-binding protein 1A\tK05366 mrcA; penicillin-binding protein 1A [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"STY0215 penicillin-binding protein 1b; peptidoglycan synthetase\tK05365 mrcB; penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]"
			},
			{
				"name":"STY2777 pbpC; penicillin-binding protein 1C\tK05367 pbpC; penicillin-binding protein 1C [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"DD-Transpeptidase (Class B PBP)",
			"children":[
			{
				"name":"STY0691 pbpA; penicillin-binding protein 2\tK05515 mrdA; penicillin-binding protein 2 [EC:3.4.16.4]"
			},
			{
				"name":"STY0142 penicillin-binding protein 3 precursor\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			},
			{
				"name":"STY1965 ftsI2; penicillin-binding protein\tK03587 ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"DD-Carboxypeptidase\/DD-Endopeptidase (Low molecular weight PBP)",
			"children":[
			{
				"name":"STY0688 D-alanine carboxypeptidase\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"STY0896 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6 precursor)\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"STY3479 Penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase)\tK07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"STY0407 ampH; penicillin-binding protein AmpH\tK18988 ampH; serine-type D-Ala-D-Ala carboxypeptidase\/endopeptidase [EC:3.4.16.4 3.4.21.-]"
			},
			{
				"name":"STY2716 putative exported protein\tK21469 pbp4b; serine-type D-Ala-D-Ala carboxypeptidase [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"Glycosyltransferase",
			"children":[
			{
				"name":"STY3505 mtgA; monofunctional biosynthetic peptidoglycan transglycosylase\tK03814 mtgA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"STY0147 cell division protein FtsW\tK03588 ftsW; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			},
			{
				"name":"STY0690 rod shape-determining protein RodA\tK05837 rodA; peptidoglycan glycosyltransferase [EC:2.4.99.28]"
			}
			]
		},
		{
			"name":"Transpeptidase",
			"children":[
			{
				"name":"STY0878 ybiS; putative exported protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"STY1255 putative exported protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"STY2218 putative exported protein\tK19236 ldtA_B_C_E; L,D-transpeptidase"
			},
			{
				"name":"STY0997 putative exported protein\tK21470 ldtD; L,D-transpeptidase"
			},
			{
				"name":"STY0357 putative exported protein\tK28919 dpaA; peptidoglycan meso-diaminopimelic acid protein amidase A [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Carboxypeptidase",
			"children":[
			{
				"name":"STY1465 pcgL; D-alanyl-D-alanine dipeptidase\tK08641 vanX; zinc D-Ala-D-Ala dipeptidase [EC:3.4.13.22]"
			}
			]
		},
		{
			"name":"Endopeptidase",
			"children":[
			{
				"name":"STY2615 penicillin-insensitive murein endopeptidase precursor\tK07261 mepA; penicillin-insensitive murein DD-endopeptidase [EC:3.4.24.-]"
			},
			{
				"name":"STY1690 putative secreted protein\tK19303 mepH; murein DD-endopeptidase [EC:3.4.-.-]"
			},
			{
				"name":"STY2450 putative lipoprotein\tK13694 mepS; murein DD-endopeptidase \/ murein LD-carboxypeptidase [EC:3.4.-.- 3.4.17.13]"
			},
			{
				"name":"STY2098 conserved hypothetical protein\tK19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Sortase"
		},
		{
			"name":"Lytic transglycosylase",
			"children":[
			{
				"name":"STY4929 slt; lytic murein transglycosylase\tK08309 slt; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			},
			{
				"name":"STY3128 membrane-bound lytic murein transglycosylase A precursor\tK08304 mltA; peptidoglycan lytic transglycosylase A [EC:4.2.2.29]"
			},
			{
				"name":"STY2952 membrane-bound lytic transglycosylase B precursor\tK08305 mltB; peptidoglycan lytic transglycosylase B [EC:4.2.2.29]"
			},
			{
				"name":"STY3267 mltC; membrane-bound lytic murein transglycosylase C\tK08306 mltC; peptidoglycan lytic transglycosylase C [EC:4.2.2.29]"
			},
			{
				"name":"STY0281 mltD; membrane-bound lytic murein transglycosylase d precursor\tK08307 mltD; peptidoglycan lytic transglycosylase D [EC:4.2.2.29]"
			},
			{
				"name":"STY1927 mltE; membrane-bound lytic murein transglycosylase E\tK08308 mltE; peptidoglycan lytic transglycosylase E [EC:4.2.2.29]"
			},
			{
				"name":"STY2813 putative exported protein\tK18691 mltF; peptidoglycan lytic transglycosylase F [EC:4.2.2.29]"
			},
			{
				"name":"STY1238 putative secreted protein\tK07082 mltG; peptidoglycan lytic transglycosylase G [EC:4.2.2.29]"
			},
			{
				"name":"STY0689 rare lipoprotein A precursor\tK03642 rlpA; peptidoglycan lytic transglycosylase [EC:4.2.2.29]"
			}
			]
		},
		{
			"name":"Amidase",
			"children":[
			{
				"name":"STY2687 probable N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"STY3129 N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"STY4715 amiB; N-acetylmuramoyl-L-alanine amidase\tK01448 amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"STY0927 putative N-acetylmuramoyl-L-alanine amidase\tK11066 amiD; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]"
			},
			{
				"name":"STY0168 AmpD protein (anhydro-N-acetylmuramyl-tripeptide amidase)\tK03806 ampD; N-acetyl-anhydromuramoyl-L-alanine amidase [EC:3.5.1.28]"
			}
			]
		},
		{
			"name":"Structural protein",
			"children":[
			{
				"name":"STY1745 major outer membrane lipoprotein\tK06078 lpp; murein lipoprotein"
			},
			{
				"name":"STY1746 lppB; major outer membrane lipoprotein\tK06078 lpp; murein lipoprotein"
			}
			]
		}
		]
	}
	]
}
