{
	"name":"sud03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins",
				"children":[
				{
					"name":"ST398NM01_2546 Type II restriction-modification system methylation subunit\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family"
			},
			{
				"name":"LysR family"
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"ST398NM01_2256 Lactose phosphotransferase system repressor\tK02530 lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor"
				},
				{
					"name":"ST398NM01_0775 Fructose repressor\tK03436 fruR2; DeoR family transcriptional regulator, fructose operon transcriptional repressor"
				},
				{
					"name":"ST398NM01_1629 CBS domain containing protein\tK23774 ccpN; DeoR family transcriptional regulator, catabolite repression regulator"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"ST398NM01_0286 Transcriptional repressor\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ST398NM01_1788 Catabolite control protein A\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"ST398NM01_2079 Sucrose operon repressor\tK03484 scrR; LacI family transcriptional regulator, sucrose operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"ST398NM01_0542 Trehalose operon transcriptional repressor\tK03486 treR2; GntR family transcriptional regulator, trehalose operon transcriptional repressor"
				},
				{
					"name":"ST398NM01_0278 hypothetical protein\tK03489 yydK; GntR family transcriptional regulator, transcriptional regulator of bglA"
				},
				{
					"name":"ST398NM01_1279 Transcriptional regulator, GntR family\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"ST398NM01_0593 Transcriptional regulator, GntR family\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"ST398NM01_2557 Gluconate operon transcriptional repressor\tK11476 gntR; GntR family transcriptional regulator, gluconate operon transcriptional repressor"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"ST398NM01_2717 IcaR\tK21453 icaR; TetR\/AcrR family transcriptional regulator, biofilm operon repressor"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family"
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"ST398NM01_2572 Transcriptional regulator, MarR family\tK15973 mhqR; MarR family transcriptional regulator, 2-MHQ and catechol-resistance regulon repressor"
				},
				{
					"name":"ST398NM01_0764 Transcriptional regulator, MarR family\tK18906 mgrA; MarR family transcriptional regulator, multiple gene regulator MgrA"
				},
				{
					"name":"ST398NM01_0414 Transcriptional regulator, MarR family\tK18909 mepR; MarR family transcriptional regulator, repressor for mepA"
				},
				{
					"name":"ST398NM01_1815 Staphylococcal accessory regulator\tK20338 rot; MarR family transcriptional regulator, global regulator for virulence"
				},
				{
					"name":"ST398NM01_2410 TcaR transcription regulator\tK21454 tcaR; MarR family transcriptional regulator, teicoplanin-associated locus regulator"
				},
				{
					"name":"ST398NM01_2439 Transcriptional regulator, MarR family\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"ST398NM01_1310 Transcriptional regulator, MerR family\tK03713 glnR; MerR family transcriptional regulator, glutamine synthetase repressor"
				},
				{
					"name":"ST398NM01_2261 Transcriptional regulator, MerR family\tK21745 adhR; MerR family transcriptional regulator, aldehyde-responsive regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"ST398NM01_1564 Ferric uptake regulation protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"ST398NM01_1619 Zinc-specific metalloregulatory protein\tK02076 zurR; Fur family transcriptional regulator, zinc uptake regulator"
				},
				{
					"name":"ST398NM01_1954 Peroxide operon regulator\tK09825 perR; Fur family transcriptional regulator, peroxide stress response regulator"
				}
				]
			},
			{
				"name":"IclR family"
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"ST398NM01_2681 Transcription regulator, crp family\tK21828 arcR; CRP\/FNR family transcriptional regulator, arginine deiminase pathway regulator"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"ST398NM01_1690 Rrf2 family protein\tK17472 cymR; Rrf2 family transcriptional regulator, cysteine metabolism repressor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"ST398NM01_2891 Arsenical resistance operon repressor\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"ST398NM01_2895 Cadmium efflux system accessory protein\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"ST398NM01_2187 Transcriptional regulator, ArsR family\tK22043 czrA; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"ST398NM01_2738 Transcriptional regulator, PadR family\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"ST398NM01_0713 Iron-dependent repressor\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"ST398NM01_2375 Transcriptional regulator, RpiR family\tK03481 glvR; RpiR family transcriptional regulator, glv operon transcriptional regulator"
				},
				{
					"name":"ST398NM01_2018 MecI\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"ST398NM01_1456 Biotin operon repressor\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"ST398NM01_2661 Transcriptional regulator, ArsR family\tK22109 gbsR; HTH-type transcriptional regulator, glycine betaine synthesis regulator"
				},
				{
					"name":"ST398NM01_0562 Pur operon repressor\tK09685 purR; HTH-type transcriptional regulator, purine operon repressor"
				},
				{
					"name":"ST398NM01_2084 Redox-sensitive transcriptional regulator Rex\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"ST398NM01_1257 CodY\tK03706 codY; transcriptional pleiotropic repressor"
				},
				{
					"name":"ST398NM01_0429 Transcriptional regulator, Cro\/CI family\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family",
				"children":[
				{
					"name":"ST398NM01_2110 hypothetical protein\tK07723 ndoAI; CopG family transcriptional regulator \/ antitoxin EndoAI"
				}
				]
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family",
				"children":[
				{
					"name":"ST398NM01_1359 Transcription antiterminator, BglG family\tK03480 glcT; transcriptional antiterminator"
				},
				{
					"name":"ST398NM01_2211 Transcription antiterminator, BglG family\tK03483 mtlR; mannitol operon transcriptional activator"
				},
				{
					"name":"ST398NM01_2690 Transcription antiterminator, BglG family\tK02538 manR; mannose operon transcriptional activator"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"ST398NM01_2128 putative cytosolic protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"ST398NM01_0440 ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"ST398NM01_2754 ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"ST398NM01_0136 SbnI\tK23371 sbnI; L-serine kinase (ATP) \/ ParB family transcriptional regulator, heme-responsive regulator [EC:2.7.1.225]"
				},
				{
					"name":"ST398NM01_1300 Glycerol uptake operon antiterminator regulatory protein\tK02443 glpP; glycerol uptake operon antiterminator"
				},
				{
					"name":"ST398NM01_1586 ArgR\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"ST398NM01_1648 HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"ST398NM01_2137 TenA\tK03707 tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]"
				},
				{
					"name":"ST398NM01_0597 CtsR\tK03708 ctsR; transcriptional regulator of stress and heat shock response"
				},
				{
					"name":"ST398NM01_0850 Central glycolytic genes regulator\tK05311 cggR; central glycolytic genes regulator"
				},
				{
					"name":"ST398NM01_1195 Uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"ST398NM01_1402 Protease synthase and sporulation negative regulatory protein PAI 2\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"ST398NM01_1740 Putative regulatory protein\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"ST398NM01_1023 Competence transcription factor\tK02250 comK; competence protein ComK"
				},
				{
					"name":"ST398NM01_1175 MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}
