{
	"name":"svi03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"Svir_31420 DNA-3-methyladenine glycosylase II\/DNA-O6-methylguanine--protein-cysteine S-methyltransferase\/Transcriptional regulator Ada\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"Svir_18480 transcriptional regulator\tK17737 dhcR; LysR family transcriptional regulator, carnitine catabolism transcriptional activator"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"Svir_16690 transcriptional regulator, DeoR family\tK02081 agaR; DeoR family transcriptional regulator, aga operon transcriptional repressor"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"Svir_07090 transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Svir_13230 transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Svir_23440 transcriptional regulator, LacI family\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Svir_38350 transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"Svir_11580 transcriptional regulator, LacI family\tK05499 cytR; LacI family transcriptional regulator, repressor for deo operon, udp, cdd, tsx, nupC, and nupG"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"Svir_15390 transcriptional regulator\tK24967 nagR; GntR family transcriptional regulator, N-acetylglucosamine utilization regulator"
				},
				{
					"name":"Svir_34690 transcriptional regulator, GntR family\tK24969 dasR; GntR family transcriptional regulator, nutrient-sensing system regulator"
				},
				{
					"name":"Svir_14010 transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Svir_18050 transcriptional regulator, GntR family\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Svir_33520 transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"Svir_09150 transcriptional regulator, GntR family\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"Svir_22500 transcriptional regulator, TetR family\tK21962 acnR; TetR\/AcrR family transcriptional regulator, transcriptional repressor of aconitase"
				},
				{
					"name":"Svir_19020 transcriptional regulator, TetR family\tK23778 rcdA; TetR\/AcrR family transcriptional regulator, regulator of biofilm formation and stress response"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"Svir_21870 transcriptional regulator, AsnC family\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family"
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"Svir_02170 predicted transcriptional regulator\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator"
				},
				{
					"name":"Svir_10940 transcriptional regulator, MerR family\tK13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR"
				},
				{
					"name":"Svir_38550 transcriptional regulator, MerR family\tK13640 hspR; MerR family transcriptional regulator, heat shock protein HspR"
				},
				{
					"name":"Svir_35010 predicted cobalamin binding protein\tK22491 litR; MerR family transcriptional regulator, light-induced transcriptional regulator"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"Svir_13670 zinc uptake regulator, Fur family\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"Svir_21260 Fe2+\/Zn2+ uptake regulation protein\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				},
				{
					"name":"Svir_20420 Fe2+\/Zn2+ uptake regulation protein\tK22297 furA; Fur family transcriptional regulator, stress-responsive regulator"
				},
				{
					"name":"Svir_21120 Fe2+\/Zn2+ uptake regulation protein\tK22297 furA; Fur family transcriptional regulator, stress-responsive regulator"
				},
				{
					"name":"Svir_36340 Fe2+\/Zn2+ uptake regulation protein\tK22297 furA; Fur family transcriptional regulator, stress-responsive regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"Svir_09640 transcriptional regulator, IclR family\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"Svir_20720 transcriptional regulator\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"Svir_21340 transcriptional regulator\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"Svir_27090 transcriptional regulator\tK13641 iclR; IclR family transcriptional regulator, acetate operon repressor"
				},
				{
					"name":"Svir_13060 transcriptional regulator, IclR family\tK02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"Svir_26880 cAMP-binding protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"Svir_36130 cAMP-binding protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"Svir_22810 rrf2 family protein, putative transcriptional regulator\tK13771 nsrR; Rrf2 family transcriptional regulator, nitric oxide-sensitive transcriptional repressor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"Svir_02010 transcriptional regulator, ArsR family\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"Svir_25900 transcriptional regulator, ArsR family\tK21903 cadC; ArsR family transcriptional regulator, lead\/cadmium\/zinc\/bismuth-responsive transcriptional repressor"
				},
				{
					"name":"Svir_13680 transcriptional regulator, ArsR family\tK22298 smtB; ArsR family transcriptional regulator, zinc-responsive transcriptional repressor"
				}
				]
			},
			{
				"name":"XRE family",
				"children":[
				{
					"name":"Svir_28370 predicted transcriptional regulator\tK07110 ramB; XRE family transcriptional regulator, fatty acid utilization regulator"
				},
				{
					"name":"Svir_25140 Helix-turn-helix protein\tK27043 clgR; XRE family transcriptional regulator, stress-response regulator"
				}
				]
			},
			{
				"name":"PadR family",
				"children":[
				{
					"name":"Svir_26090 predicted transcriptional regulator\tK26740 vanR; PadR family transcriptional regulator, regulator of vanillate utilization"
				},
				{
					"name":"Svir_09510 transcriptional regulator, PadR family\tK10947 K10947; PadR family transcriptional regulator"
				}
				]
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"Svir_27510 Mn-dependent transcriptional regulator\tK26252 dtxR; DtxR family transcriptional regulator, iron-dependent repressor"
				},
				{
					"name":"Svir_33150 Mn-dependent transcriptional regulator\tK03709 troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator"
				},
				{
					"name":"Svir_37280 predicted transcriptional regulator\tK02171 blaI; BlaI family transcriptional regulator, penicillinase repressor"
				},
				{
					"name":"Svir_05900 birA, biotin-(acetyl-CoA-carboxylase) ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"Svir_02840 AT-rich DNA-binding protein\tK01926 rex; redox-sensing transcriptional repressor"
				},
				{
					"name":"Svir_26750 hypothetical protein\tK27097 espR; ESX-1-secreted protein regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"Svir_04680 Transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_08190 transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_12870 Transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_30700 transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_31070 transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_36240 transcription factor WhiB\tK18955 whiB1_2_3_4; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_07550 Transcription factor WhiB-like protein\tK18958 whiB7; WhiB family transcriptional regulator, redox-sensing transcriptional regulator"
				},
				{
					"name":"Svir_36760 uncharacterized conserved protein\tK21600 csoR; CsoR family transcriptional regulator, copper-sensing transcriptional repressor"
				},
				{
					"name":"Svir_20880 purine catabolism regulator-like protein\tK09684 pucR; PucR family transcriptional regulator, purine catabolism regulatory protein"
				},
				{
					"name":"Svir_39730 chromosome segregation DNA-binding protein\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"Svir_35090 transcriptional regulator, CarD family\tK07736 carD; CarD family transcriptional regulator, regulator of rRNA transcription"
				},
				{
					"name":"Svir_25580 transcriptional regulator, ArgR family\tK03402 argR; transcriptional regulator of arginine metabolism"
				},
				{
					"name":"Svir_13540 heat-inducible transcription repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"Svir_19070 phenylacetic acid-responsive transcriptional repressor\tK02616 paaX; phenylacetic acid degradation operon negative regulatory protein"
				},
				{
					"name":"Svir_15540 pyrimidine operon attenuation protein\/uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"Svir_39570 predicted transcriptional regulator\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"Svir_27580 transcriptional regulator NrdR\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"Svir_24980 mraZ protein\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}