{
	"name":"tch04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"CHITON_1608 LSU ribosomal protein L40e\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"CHITON_0466 SSU ribosomal protein S27Ae\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)"
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme"
		},
		{
			"name":"UBL-activating enzymes"
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes"
		},
		{
			"name":"UBL-conjugating enzymes"
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"HECT type E3 associated proteins"
			}
			]
		},
		{
			"name":"U-box type E3"
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins"
			},
			{
				"name":"CBL proteins"
			},
			{
				"name":"SINA (Seven in absentia) proteins"
			},
			{
				"name":"Ligand of Numb proteins"
			},
			{
				"name":"March proteins"
			},
			{
				"name":"MDM2\/MDM4 proteins"
			},
			{
				"name":"NFX1 proteins"
			},
			{
				"name":"Pellino proteins"
			},
			{
				"name":"Peripheral membrane proteins"
			},
			{
				"name":"RBR proteins"
			},
			{
				"name":"TRAF proteins"
			},
			{
				"name":"TRIM\/RBCC proteins"
			},
			{
				"name":"UBR box proteins"
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3"
			}
			]
		},
		{
			"name":"Atypical E3"
		},
		{
			"name":"UBL E3 ligases"
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit (F-box)"
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)"
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein"
				},
				{
					"name":"Target recognizing subunit (DCAF)"
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adoptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein"
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Target recognizing subunit"
				},
				{
					"name":"Other subunits"
				}
				]
			},
			{
				"name":"BRCC complex"
			},
			{
				"name":"KPC complex"
			},
			{
				"name":"LUBAC complex"
			},
			{
				"name":"CTLH complex"
			},
			{
				"name":"ERAD complex"
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex"
			},
			{
				"name":"STUB1-CHIC2  complex"
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins"
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH"
			},
			{
				"name":"UBP\/USP"
			},
			{
				"name":"OTU"
			},
			{
				"name":"MJD"
			},
			{
				"name":"MINDY"
			},
			{
				"name":"JAMM"
			},
			{
				"name":"PPPDE"
			},
			{
				"name":"ZUFSP"
			},
			{
				"name":"BRISC complex"
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"COP9 signalosome (CSN) complex"
			}
			]
		}
		]
	}
	]
}