{
	"name":"thi04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"THI_1273 htpG; Chaperone protein htpG (Heat shock protein htpG) (High temperature protein G) (Heat shock protein C62.5)\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"THI_0525 eno1; Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"THI_2130 eno2; Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"THI_2657 eno3; Enolase (2-phosphoglycerate dehydratase) (2-phospho-D-glycerate hydro-lyase)\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"THI_0162 cbbG; Glyceraldehyde-3-phosphate dehydrogenase A (GAPDH-A)\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"THI_0163 cbbKP; phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"THI_1050 pykA; pyruvate kinase II (PK-2)\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"THI_2527 putative Pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"THI_0441 ppiA; Peptidyl-prolyl cis-trans isomerase A precursor (PPIase A) (Rotamase A) (Cyclophilin A)\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
			},
			{
				"name":"THI_3375 putative Peroxiredoxin\tK03386 PRDX2_4; peroxiredoxin 2\/4 [EC:1.11.1.24]"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"THI_0833 groL; 60 kDa chaperonin (Protein Cpn60) (groEL protein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"THI_2212 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"THI_1383 putative glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"THI_2184 guaB; Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"THI_3434 tuf; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"THI_3726 tufA; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"THI_1120 hinT; purine nucleoside phosphoramidase\tK02503 HINT1_2; histidine triad (HIT) family protein [EC:3.9.1.-]"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells"
		},
		{
			"name":"Exosomal proteins of epithelial cells"
		},
		{
			"name":"Exosomal proteins of hepatic cells"
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"THI_1099 putative long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"THI_2917 fadD; Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase) (Acyl-CoA synthetase)\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"THI_0833 groL; 60 kDa chaperonin (Protein Cpn60) (groEL protein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"THI_1641 phbA1; acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"THI_3278 phbA2; acetyl-CoA acetyltransferase (Acetoacetyl-CoA thiolase)\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"THI_2563 ahcY; Adenosylhomocysteinase (S-adenosyl-L-homocysteine hydrolase) (AdoHcyase)\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"THI_2095 adk; Adenylate kinase (ATP-AMP transphosphorylase) (AK)\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"THI_0344 apt; Adenine phosphoribosyltransferase (APRT)\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"THI_0654 argH; Argininosuccinate lyase (Arginosuccinase) (ASAL)\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"THI_2570 argG; Argininosuccinate synthase (Citrulline--aspartate ligase)\tK01940 argG; argininosuccinate synthase [EC:6.3.4.5]"
			},
			{
				"name":"THI_3626 dht; D-hydantoinase (Dihydropyrimidinase) (DHPase)\tK01464 DPYS; dihydropyrimidinase [EC:3.5.2.2]"
			},
			{
				"name":"THI_2216 cbbFC2; Fructose-1,6-bisphosphatase (D-fructose-1,6-bisphosphate 1-phosphohydrolase) (FBPase)\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
			},
			{
				"name":"THI_1389 glgB; 1,4-alpha-glucan branching enzyme (Glycogen branching enzyme) (BE) (1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase)\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"THI_0733 glpK; Glycerol kinase (ATP:glycerol 3-phosphotransferase) (Glycerokinase) (GK)\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"THI_0200 putative glutamine synthetase (GS)\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"THI_1383 putative glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"THI_0330 hemB; Delta-aminolevulinic acid dehydratase (Porphobilinogen synthase) (ALAD) (ALADH)\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"THI_1260 lly; 4-hydroxyphenylpyruvate dioxygenase (4HPPD) (HPD) (HPPDase)\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"THI_0146 putative Pterin-4a-carbinolamine dehydratase\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"THI_1191 putative pterin-4-alpha-carbinolamine dehydratase (PHS) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD)\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"THI_3820 putative Glyoxylate reductase gyaR\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"THI_3260 purH; Bifunctional purine biosynthesis protein purH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase); IMP cyclohydrolase (Inosinicase) (IMP synthetase) (ATIC)]\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			},
			{
				"name":"THI_1192 putative Peptidase M48, Ste24p\tK06013 STE24; STE24 endopeptidase [EC:3.4.24.84]"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"THI_1099 putative long-chain-fatty-acid--CoA ligase\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"THI_2917 fadD; Long-chain-fatty-acid--CoA ligase (Long-chain acyl-CoA synthetase) (Acyl-CoA synthetase)\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"THI_0061 putative Dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"THI_1673 odhL; Dihydrolipoyl dehydrogenase (E3 component of 2-oxoglutarate dehydrogenase complex) (Dihydrolipoamide dehydrogenase)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"THI_2235 putative Dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"THI_2678 lpdA; Dihydrolipoyl dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) (Dihydrolipoamide dehydrogenase) (Glycine cleavage system L protein)\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"THI_1679 etfA; electron transfer flavoprotein alpha-subunit (Alpha-ETF)(Electron transfer flavoprotein large subunit) (ETFLS)\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"THI_3422 gdhA; glutamate dehydrogenase (GDH)\tK00261 GLUD1_2; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]"
			},
			{
				"name":"THI_1392 zwf; Glucose-6-phosphate 1-dehydrogenase (G6PD)\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"THI_2184 guaB; Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD)\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"THI_2212 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"THI_0833 groL; 60 kDa chaperonin (Protein Cpn60) (groEL protein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"THI_3434 tuf; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"THI_3726 tufA; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"THI_0833 groL; 60 kDa chaperonin (Protein Cpn60) (groEL protein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"THI_1383 putative glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI)\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"THI_1392 zwf; Glucose-6-phosphate 1-dehydrogenase (G6PD)\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"THI_2212 dnaK; Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70)\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"THI_2642 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"THI_3434 tuf; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"THI_3726 tufA; Elongation factor Tu (EF-Tu) (P-43)\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"THI_0833 groL; 60 kDa chaperonin (Protein Cpn60) (groEL protein)\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"THI_1392 zwf; Glucose-6-phosphate 1-dehydrogenase (G6PD)\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"THI_0970 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"THI_2642 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"THI_0970 gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase (Phosphoglyceromutase) (PGAM) (BPG-dependent PGAM) (dPGM)\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
			},
			{
				"name":"THI_2642 tpiA; Triosephosphate isomerase (TIM) (Triose-phosphate isomerase)\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}