{
	"name":"thj03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"104799099 origin of replication complex subunit 1B-like\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"104806568 origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"104809222 LOW QUALITY PROTEIN: origin of replication complex subunit 2-like\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"104821161 origin of replication complex subunit 3\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"104805050 origin of replication complex subunit 4 isoform X1\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"104825846 origin of replication complex subunit 5 isoform X1\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"104822117 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"104800876 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"104825264 CDT1-like protein b\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"104826211 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"104800725 cell division control protein 6 homolog\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"104816080 cell division control protein 6 homolog B-like\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"104801409 DNA replication licensing factor MCM2\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"104806124 DNA replication licensing factor MCM3\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"104819624 DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"104808931 DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"104811945 DNA replication licensing factor MCM6 isoform X1\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"104801305 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"104799792 putative cyclin-A3-1 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104800218 cyclin-A1-2 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104806825 cyclin-A1-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104808211 cyclin-A2-4-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104808251 cyclin-A1-1-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104812477 cyclin-A2-4-like isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104813571 cyclin-A2-4-like\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104814180 putative cyclin-A3-1 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104815036 cyclin-A2-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104820502 putative cyclin-A3-1 isoform X1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104825754 putative cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"104818174 cyclin-dependent kinase A-1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"104825029 cell division control protein 2 homolog A-like isoform X1\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"104807924 uncharacterized protein LOC104807924 isoform X1\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"104812498 probable DNA replication complex GINS protein PSF1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"104827330 DNA replication complex GINS protein PSF2\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"104824313 DNA replication complex GINS protein PSF3-like\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"104827096 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"104800232 DNA topoisomerase 2-binding protein 1-A-like\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"104810225 DNA topoisomerase 2-binding protein 1-like isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"104813680 DNA topoisomerase 2-binding protein 1-A isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"104815922 BRCT domain-containing protein At4g02110-like isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"104825943 BRCT domain-containing protein At4g02110\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"104820520 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"104808789 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"104816318 probable DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"104819509 probable DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"104807811 protein MCM10 homolog isoform X1\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"104803295 mini-chromosome maintenance complex-binding protein-like\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				},
				{
					"name":"104812375 mini-chromosome maintenance complex-binding protein-like\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"104827210 DNA polymerase alpha catalytic subunit\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"104807895 DNA polymerase alpha subunit B isoform X1\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"104809335 DNA primase small subunit isoform X1\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"104807138 probable DNA primase large subunit\tK02685 PRI2; DNA primase large subunit"
				},
				{
					"name":"104825491 probable DNA primase large subunit isoform X1\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"104826411 DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"104810934 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"104826426 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"104818425 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"104824475 DNA polymerase delta small subunit isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"104808089 uncharacterized protein LOC104808089\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"104820303 uncharacterized protein LOC104820303\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"104804633 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"104806192 replication protein A 70 kDa DNA-binding subunit E-like isoform X1\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"104819400 replication protein A 70 kDa DNA-binding subunit B-like\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"104826582 replication protein A 70 kDa DNA-binding subunit A isoform X1\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"104802929 replication protein A 32 kDa subunit B\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"104803594 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"104804847 replication protein A 14 kDa subunit B\tK10740 RPA3; replication factor A3"
				},
				{
					"name":"104805250 replication protein A 14 kDa subunit B-like isoform X1\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"104810945 replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"104800216 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"104809417 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"104800207 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"104824562 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"104824207 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"104811993 ribonuclease H2 subunit B isoform X1\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"104824253 uncharacterized protein C12B10.15c\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"104815801 proliferating cell nuclear antigen 2\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"104826301 proliferating cell nuclear antigen 2-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"104808236 DNA replication ATP-dependent helicase\/nuclease DNA2-like\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"104818763 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"104812654 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"104813917 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"104818327 DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"104800577 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"104800189 uncharacterized protein LOC104800189 isoform X1\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"104798456 DNA (cytosine-5)-methyltransferase CMT2 isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"104809536 putative DNA (cytosine-5)-methyltransferase CMT1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"104815273 DNA (cytosine-5)-methyltransferase CMT3\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"104820805 DNA (cytosine-5)-methyltransferase 1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"104823726 DNA (cytosine-5)-methyltransferase 1-like isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"104802799 uncharacterized protein LOC104802799\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"104800470 cyclin-B1-4\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104804291 cyclin-B2-1-like isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104805940 cyclin-SDS\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104808136 putative cyclin-B3-1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104809782 cyclin-B2-4-like isoform X2\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104809968 cyclin-B1-3-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104811466 cyclin-B2-4-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104816598 cyclin-B1-3 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104816953 cyclin-B1-4-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"104819723 cyclin-B2-1-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex"
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"104800748 CST complex subunit STN1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"104805904 CST complex subunit TEN1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"104827206 LOW QUALITY PROTEIN: telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"104802867 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"104827273 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"104813898 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"104818364 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"104804047 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"104814520 H\/ACA ribonucleoprotein complex subunit 3-like protein\tK11130 NOP10; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"104803283 LOW QUALITY PROTEIN: H\/ACA ribonucleoprotein complex subunit 4\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"104816817 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"104824422 H\/ACA ribonucleoprotein complex subunit 4-like\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"104827206 LOW QUALITY PROTEIN: telomerase reverse transcriptase\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"104806243 small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"104812077 small nuclear ribonucleoprotein-associated protein B'-like\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"104801227 small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"104819017 small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"104822445 small nuclear ribonucleoprotein Sm D1-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"104802174 small nuclear ribonucleoprotein Sm D2-like isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"104817495 small nuclear ribonucleoprotein Sm D2-like\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"104809773 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"104811465 small nuclear ribonucleoprotein SmD3b-like\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"104803508 small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"104803931 small nuclear ribonucleoprotein E-like\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"104803496 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"104803938 probable small nuclear ribonucleoprotein F isoform X1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"104823127 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"104826821 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"104800216 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"104809417 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"104800207 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"104824562 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"104813315 double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"104826172 DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"104820929 nijmegen breakage syndrome 1 protein\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"104818218 serine\/threonine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"104809610 ATP-dependent DNA helicase Q-like 4A isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"104819729 ATP-dependent DNA helicase Q-like 3\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"104807928 DNA repair endonuclease UVH1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"104800882 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"104801277 poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"104817794 G patch domain-containing protein 4\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"104812517 regulator of telomere elongation helicase 1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"104818196 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"104810308 transcription factor Pur-alpha 1 isoform X1\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"104806275 telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"104801375 protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"104817053 protein SDE2 homolog isoform X1\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"104817828 protein RTF2 homolog\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"104811639 DNA topoisomerase 1 alpha\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"104817691 DNA topoisomerase 1 alpha\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"104820131 DNA topoisomerase 2\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"104800954 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"104818422 DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"104803364 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				},
				{
					"name":"104821851 single-stranded DNA-binding protein, mitochondrial-like\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"104817879 DNA polymerase I A, chloroplastic\/mitochondrial\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"104808236 DNA replication ATP-dependent helicase\/nuclease DNA2-like\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"104818763 flap endonuclease 1 isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"104800577 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"104826959 DNA gyrase subunit A, chloroplastic\/mitochondrial isoform X1\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"104816412 DNA gyrase subunit B, chloroplastic isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"104826889 DNA gyrase subunit B, mitochondrial-like isoform X1\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"104816912 DNA topoisomerase 6 subunit B isoform X1\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}