{
	"name":"tmu03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"101355611 proteasome subunit alpha type-6 isoform X1\tK02730 PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"101355548 proteasome subunit alpha type-2\tK02726 PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"101356505 proteasome subunit alpha type-4\tK02728 PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"101347133 proteasome subunit alpha type-7\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"101354620 proteasome subunit alpha type-7-like isoform X1\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"101347799 proteasome subunit alpha type-5\tK02729 PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"101352422 proteasome subunit alpha type-1\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"101340422 proteasome subunit alpha type-3\tK02727 PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"101343598 proteasome subunit beta type-6\tK02738 PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"101359620 proteasome subunit beta type-7\tK02739 PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"101348858 proteasome subunit beta type-3 isoform X1\tK02735 PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"101346461 proteasome subunit beta type-2\tK02734 PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"101343830 proteasome subunit beta type-5\tK02737 PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"101359762 proteasome subunit beta type-1\tK02732 PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"101343402 proteasome subunit beta type-4\tK02736 PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]"
				},
				{
					"name":"101342060 proteasome subunit beta type-8\tK02740 PSMB8; 20S proteasome subunit beta 8 [EC:3.4.25.1]"
				},
				{
					"name":"101341554 proteasome subunit beta type-9 isoform X1\tK02741 PSMB9; 20S proteasome subunit beta 9 [EC:3.4.25.1]"
				},
				{
					"name":"101354564 proteasome subunit beta type-10\tK02733 PSMB10; 20S proteasome subunit beta 10 [EC:3.4.25.1]"
				},
				{
					"name":"101348827 proteasome subunit beta type-11\tK11598 PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"101360911 26S proteasome regulatory subunit 7\tK03061 PSMC2; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"101341654 26S proteasome regulatory subunit 4\tK03062 PSMC1; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"101356704 26S proteasome regulatory subunit 6B\tK03063 PSMC4; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"101354396 26S proteasome regulatory subunit 10B\tK03064 PSMC6; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"101353268 26S proteasome regulatory subunit 6A\tK03065 PSMC3; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"101353736 26S proteasome regulatory subunit 8\tK03066 PSMC5; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"101358856 26S proteasome non-ATPase regulatory subunit 2\tK03028 PSMD2; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"101355826 26S proteasome non-ATPase regulatory subunit 1 isoform X3\tK03032 PSMD1; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"101359024 26S proteasome non-ATPase regulatory subunit 3\tK03033 PSMD3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"101355804 26S proteasome non-ATPase regulatory subunit 9\tK06693 PSMD9; 26S proteasome regulatory subunit N4"
					},
					{
						"name":"101349534 26S proteasome non-ATPase regulatory subunit 12\tK03035 PSMD12; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"101345656 26S proteasome non-ATPase regulatory subunit 11\tK03036 PSMD11; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"101344747 26S proteasome non-ATPase regulatory subunit 6\tK03037 PSMD6; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"101351436 26S proteasome non-ATPase regulatory subunit 7\tK03038 PSMD7; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"101340678 26S proteasome non-ATPase regulatory subunit 13\tK03039 PSMD13; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"101345005 26S proteasome non-ATPase regulatory subunit 4\tK03029 PSMD4; 26S proteasome regulatory subunit N10"
					},
					{
						"name":"101346477 26S proteasome non-ATPase regulatory subunit 14\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"101355652 26S proteasome non-ATPase regulatory subunit 8\tK03031 PSMD8; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"101346449 proteasomal ubiquitin receptor ADRM1 isoform X1\tK06691 RPN13; 26S proteasome regulatory subunit N13"
					},
					{
						"name":"101359313 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"101351312 26S proteasome non-ATPase regulatory subunit 5 isoform X1\tK06692 PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					},
					{
						"name":"101348872 26S proteasome non-ATPase regulatory subunit 10 isoform X1\tK06694 PSMD10; 26S proteasome non-ATPase regulatory subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)",
				"children":[
				{
					"name":"101344933 proteasome activator complex subunit 1 isoform X3\tK06696 PSME1; proteasome activator subunit 1 (PA28 alpha)"
				},
				{
					"name":"101345183 proteasome activator complex subunit 2\tK06697 PSME2; proteasome activator subunit 2 (PA28 beta)"
				},
				{
					"name":"101359250 proteasome activator complex subunit 3 isoform X1\tK06698 PSME3; proteasome activator subunit 3 (PA28 gamma)"
				}
				]
			},
			{
				"name":"PA200",
				"children":[
				{
					"name":"101341621 proteasome activator complex subunit 4 isoform X2\tK06699 PSME4; proteasome activator subunit 4"
				}
				]
			},
			{
				"name":"PI31",
				"children":[
				{
					"name":"101351200 proteasome inhibitor PI31 subunit isoform X1\tK06700 PSMF1; proteasome inhibitor subunit 1 (PI31)"
				}
				]
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"101353428 proteasome maturation protein\tK11599 POMP; proteasome maturation protein"
				},
				{
					"name":"101357165 proteasome assembly chaperone 1\tK11875 PSMG1; proteasome assembly chaperone 1"
				},
				{
					"name":"101347223 proteasome assembly chaperone 2\tK11876 PSMG2; proteasome assembly chaperone 2"
				},
				{
					"name":"101342363 proteasome assembly chaperone 3\tK11877 PSMG3; proteasome assembly chaperone 3"
				},
				{
					"name":"101361820 proteasome assembly chaperone 4\tK11878 PSMG4; proteasome assembly chaperone 4"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"101343480 eukaryotic translation initiation factor 3 subunit E\tK03250 EIF3E; translation initiation factor 3 subunit E"
				},
				{
					"name":"101348660 heat shock 70 kDa protein 1-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101348919 heat shock 70 kDa protein 1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101351001 heat shock 70 kDa protein 6\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101354728 heat shock cognate 71 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101356536 LOW QUALITY PROTEIN: heat shock cognate 71 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101356837 LOW QUALITY PROTEIN: heat shock 70 kDa protein-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101357110 heat shock 70 kDa protein 1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"101352690 heat shock-related 70 kDa protein 2\tK26598 HSPA2; heat shock 70kDa protein 2"
				},
				{
					"name":"101341605 heat shock protein HSP 90-alpha-like isoform X1\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"101343785 heat shock protein HSP 90-beta\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"101348117 LOW QUALITY PROTEIN: heat shock protein HSP 90-alpha-like\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"101349955 heat shock protein HSP 90-alpha isoform X1\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"101346429 interferon gamma\tK04687 IFNG; interferon gamma"
				},
				{
					"name":"101350914 RNA-binding protein NOB1\tK11883 NOB1; RNA-binding protein NOB1"
				},
				{
					"name":"101343659 RNA-binding protein PNO1\tK11884 PNO1; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"101349937 UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"101354050 UV excision repair protein RAD23 homolog A isoform X2\tK10839 RAD23; UV excision repair protein RAD23"
				},
				{
					"name":"101346442 ubiquilin-4\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"101348314 ubiquilin-3\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"101355318 ubiquilin-2 isoform X2\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"101359588 LOW QUALITY PROTEIN: ubiquilin-4-like\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"101361194 ubiquilin-1 isoform X1\tK04523 UBQLN; ubiquilin"
				},
				{
					"name":"101348059 ubiquilin-like protein\tK22254 UBQLNL; ubiquilin-like protein"
				},
				{
					"name":"101348567 ubiquilin-3-like\tK22254 UBQLNL; ubiquilin-like protein"
				},
				{
					"name":"101357798 protein DDI1 homolog 2 isoform X3\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"101361125 protein DDI1 homolog 1\tK11885 DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"101360216 LOW QUALITY PROTEIN: NEDD8 ultimate buster 1\tK29014 NUB1; NEDD8 ultimate buster 1"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"101343575 proteasome-associated protein ECM29 homolog isoform X2\tK11886 ECM29; proteasome component ECM29"
				},
				{
					"name":"101355541 proteasomal ATPase-associated factor 1 isoform X1\tK11887 PAAF1; proteasomal ATPase-associated factor 1"
				},
				{
					"name":"101362003 homologous-pairing protein 2 homolog\tK06695 PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein"
				},
				{
					"name":"101343481 JNK1\/MAPK8-associated membrane protein isoform X1\tK28966 JKAMP; JNK1\/MAPK8-associated membrane protein"
				},
				{
					"name":"101348180 midnolin\tK29091 MIDN; midnolin"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)"
		},
		{
			"name":"Bacterial regulatory particles"
		},
		{
			"name":"Archaeal regulatory particles"
		}
		]
	}
	]
}