{
	"name":"tod03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"119234131 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"119244884 ALKBH2; DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"119255345 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"119252730 ASCC3; activating signal cointegrator 1 complex subunit 3 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"119244883 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"119247025 LOW QUALITY PROTEIN: uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"119260999 CCNO; cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"119247359 TDG; G\/T mismatch-specific thymine DNA glycosylase isoform X1\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"119247368 LOW QUALITY PROTEIN: G\/T mismatch-specific thymine DNA glycosylase-like\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"119242405 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"119248004 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"119236175 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"119255325 OGG1; N-glycosylase\/DNA lyase\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"119238407 NEIL1; endonuclease 8-like 1 isoform X1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"119258042 NEIL2; endonuclease 8-like 2 isoform X1\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"119257998 NEIL3; endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"119242031 NTHL1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"119238853 APEX1; DNA-(apurinic or apyrimidinic site) endonuclease\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"119246129 APEX2; DNA-(apurinic or apyrimidinic site) endonuclease 2 isoform X1\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"119249610 POLD1; DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"119231225 POLD2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"119255625 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"119249917 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"119245099 POLE; DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"119239064 POLE2; DNA polymerase epsilon subunit 2 isoform X3\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"119232274 POLE3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"119258584 POLE4; LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 4\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"119232790 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"119238731 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"119250081 FEN1; flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"119249503 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"119257854 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"119249416 XRCC1; DNA repair protein XRCC1 isoform X1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"119232568 LIG3; DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"119239290 TDP1; tyrosyl-DNA phosphodiesterase 1 isoform X2\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"119230949 APTX; aprataxin isoform X2\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"119253332 aprataxin-like\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"119259023 APLF; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"119249604 PNKP; bifunctional polynucleotide phosphatase\/kinase isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"119239393 LOW QUALITY PROTEIN: high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119241258 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119258812 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119233545 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"119244558 PARP1; poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"119238848 PARP2; poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"119258933 PARP4; protein mono-ADP-ribosyltransferase PARP4 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"119260893 PARP3; protein mono-ADP-ribosyltransferase PARP3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"119256011 XPC; DNA repair protein complementing XP-C cells\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"119232900 RAD23B; UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"119241010 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"119246488 CETN2; centrin-2 isoform X1\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"119247226 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"119245926 CUL4B; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119250814 cullin-4B-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119259709 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119250038 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"119255301 DDB2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"119230578 POLR2A; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"119260794 POLR2B; DNA-directed RNA polymerase II subunit RPB2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"119249264 POLR2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"119254718 POLR2D; DNA-directed RNA polymerase II subunit RPB4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"119240496 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"119247275 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"119250099 POLR2G; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"119257353 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"119250244 POLR2I; DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"119246429 DNA-directed RNA polymerases I, II, and III subunit RPABC5-like\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"119249844 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"119257021 DNA-directed RNA polymerases I, II, and III subunit RPABC5-like\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"119241544 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"119238011 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"119247226 RBX1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"119245926 CUL4B; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119250814 cullin-4B-like\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119259709 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"119250038 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"119260218 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"119234312 DNA excision repair protein ERCC-6-like isoform X1\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"119261008 UVSSA; UV-stimulated scaffold protein A\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"119240984 ELOF1; transcription elongation factor 1 homolog isoform X2\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"119255706 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB isoform X1\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"119249440 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"119255515 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"119261438 GTF2H2C; general transcription factor IIH subunit 2-like protein isoform X2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"119245059 GTF2H3; general transcription factor IIH subunit 3 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"119252122 GTF2H4; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"119252984 GTF2H5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"119260812 CDK7; cyclin-dependent kinase 7 isoform X2\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"119260517 CCNH; cyclin-H isoform X1\tK06634 CCNH; cyclin H"
					},
					{
						"name":"119239159 MNAT1; CDK-activating kinase assembly factor MAT1 isoform X2\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"119230772 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"119236186 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"119242680 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"119261340 LOW QUALITY PROTEIN: replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"119232453 XPA; DNA repair protein complementing XP-A cells\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"119249445 ERCC1; DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"119241914 ERCC4; DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"119259745 ERCC5; DNA excision repair protein ERCC-5\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"119249503 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"119234594 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"119244809 CCDC117; coiled-coil domain-containing protein 117 isoform X1\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"119259222 CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"119238716 CIAO2A; cytosolic iron-sulfur assembly component 2A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"119248924 CIAO2B; cytosolic iron-sulfur assembly component 2B\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"119256261 CUL3; cullin-3 isoform X1\tK03869 CUL3; cullin 3"
					},
					{
						"name":"119240889 CUL5; cullin-5\tK10612 CUL5; cullin 5"
					},
					{
						"name":"119240666 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"119248271 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"119242010 ELOB; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"119235531 ELOA; elongin-A isoform X1\tK15076 ELOA; elongin-A"
					},
					{
						"name":"119243707 elongin-A-like\tK15076 ELOA; elongin-A"
					},
					{
						"name":"119232664 UBAP2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"119236514 UBAP2L; ubiquitin-associated protein 2-like isoform X4\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"119259324 MSH2; LOW QUALITY PROTEIN: DNA mismatch repair protein Msh2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"119260874 MSH3; DNA mismatch repair protein Msh3 isoform X1\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"119259318 MSH6; DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"119256029 PMS1; PMS1 protein homolog 1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"119257886 MLH1; DNA mismatch repair protein Mlh1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"119241655 PMS2; mismatch repair endonuclease PMS2 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"119239357 MLH3; LOW QUALITY PROTEIN: DNA mismatch repair protein Mlh3\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"119249610 POLD1; DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"119231225 POLD2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"119255625 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"119249917 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"119230772 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"119236186 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"119242680 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"119261340 LOW QUALITY PROTEIN: replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"119261404 RFC1; LOW QUALITY PROTEIN: replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"119241504 RFC2; replication factor C subunit 2 isoform X2\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"119257380 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"119244935 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"119258836 RFC3; LOW QUALITY PROTEIN: replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"119232790 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"119238731 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"119244512 EXO1; exonuclease 1 isoform X2\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"119239393 LOW QUALITY PROTEIN: high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119241258 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119258812 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"119249503 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"119238562 WDR76; WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"119240393 MRE11; double-strand break repair protein MRE11 isoform X4\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"119243487 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"119239930 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119255190 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119261163 ABRAXAS1; BRCA1-A complex subunit Abraxas 1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"119237193 UIMC1; BRCA1-A complex subunit RAP80 isoform X2\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"119241092 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"119259441 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"119245773 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119230767 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"119257915 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119243142 RBBP8; DNA endonuclease RBBP8\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"119240393 MRE11; double-strand break repair protein MRE11 isoform X4\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"119243487 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"119239930 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119258825 BRCA2; breast cancer type 2 susceptibility protein isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"119241823 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"119238491 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"119238491 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"119239217 RAD51B; DNA repair protein RAD51 homolog 2 isoform X7\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"119231687 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"119230370 RAD51D; DNA repair protein RAD51 homolog 4 isoform X1\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"119249125 XRCC2; DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"119239476 XRCC3; DNA repair protein XRCC3\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"119247845 RAD52; DNA repair protein RAD52 homolog isoform X1\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"119232175 RDM1; RAD52 motif-containing protein 1 isoform X1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"119236417 RAD54L; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"119260815 RAD54L2; helicase ARIP4 isoform X1\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"119239518 RAD54B; DNA repair and recombination protein RAD54B isoform X1\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"119247647 RECQL; ATP-dependent DNA helicase Q1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"119257791 WRN; bifunctional 3'-5' exonuclease\/ATP-dependent helicase WRN isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"119244243 BLM; recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"119240391 RECQL4; ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"119232004 RECQL5; ATP-dependent DNA helicase Q5 isoform X2\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"119244243 BLM; recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"119230543 TOP3A; DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"119233454 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"119232985 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"119241930 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"119230772 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"119236186 RPA2; replication protein A 32 kDa subunit\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"119242680 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"119261340 LOW QUALITY PROTEIN: replication protein A 14 kDa subunit-like\tK10740 RPA3; replication factor A3"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"119241773 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit isoform X1\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"119236848 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"119243192 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"119231192 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X1\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"119239463 PPP4R3A; serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"119246769 PPP4R3C; protein PPP4R3C isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"119258962 PPP4R3B; serine\/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"119239430 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"119250522 AP5B1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"119239127 AP5M1; AP-5 complex subunit mu-1 isoform X1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"119254260 AP5S1; AP-5 complex subunit sigma-1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"119241637 AP5Z1; AP-5 complex subunit zeta-1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					},
					{
						"name":"119248603 LOW QUALITY PROTEIN: AP-5 complex subunit zeta-1-like\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"119232771 SMC5; structural maintenance of chromosomes protein 5 isoform X1\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"119259534 SMC6; LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"119259601 LOW QUALITY PROTEIN: structural maintenance of chromosomes protein 6-like\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"119258751 LRATD1; protein LRATD1\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"119241810 NSMCE1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"119238121 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"119244349 NSMCE3; non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"119233650 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"119247355 EID3; EP300-interacting inhibitor of differentiation 3\tK22826 EID3; EP300-interacting inhibitor of differentiation 3"
					},
					{
						"name":"119261449 SLF1; SMC5-SMC6 complex localization factor protein 1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"119233661 SLF2; SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"119236646 SIMC1; SUMO-interacting motif-containing protein 1 isoform X1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"119232833 EME1; crossover junction endonuclease EME1 isoform X1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"119239223 EXD2; exonuclease 3'-5' domain-containing protein 2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"119249962 MUS81; crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"119239966 26S proteasome complex subunit SEM1-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"119242544 SEM1; 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"119246774 26S proteasome complex subunit SEM1-like\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"119230397 SWI5; DNA repair protein SWI5 homolog\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"119234252 SFR1; swi5-dependent recombination DNA repair protein 1 homolog isoform X2\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"119241782 SLX1A; structure-specific endonuclease subunit SLX1 isoform X1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"119242373 SLX4; LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"119259533 GEN1; flap endonuclease GEN homolog 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"119238568 SPG11; spatacsin\tK19026 SPG11; spatacsin"
					},
					{
						"name":"119239216 ZFYVE26; zinc finger FYVE domain-containing protein 26\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"119247812 RAD51AP1; RAD51-associated protein 1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"119234897 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"119244278 MORF4L1; mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"119233079 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"119231684 FIGNL1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"119241511 SPIDR; DNA repair-scaffolding protein isoform X3\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"119238071 LRATD2; protein LRATD2\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"119241626 BRAT1; BRCA1-associated ATM activator 1 isoform X1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"119257155 CFAP410; cilia- and flagella-associated protein 410 isoform X3\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"119240593 HDGFL2; hepatoma-derived growth factor-related protein 2 isoform X1\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"119232477 ZSWIM7; zinc finger SWIM domain-containing protein 7\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"119239995 SWSAP1; ATPase SWSAP1 isoform X2\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"119255646 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X1\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"119257071 HSF2BP; heat shock factor 2-binding protein\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"119252719 MMS22L; protein MMS22-like\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"119250991 LOW QUALITY PROTEIN: tonsoku-like protein\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"119259477 TONSL; tonsoku-like protein isoform X1\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"119261315 BOD1L1; LOW QUALITY PROTEIN: biorientation of chromosomes in cell division protein 1-like 1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"119247370 PARPBP; PCNA-interacting partner isoform X1\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"119230535 HROB; homologous recombination OB-fold protein isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"119232730 MCM8; DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"119252832 MCM9; DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"119249348 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"119250118 HNRNPUL2; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"119237207 MRNIP; MRN complex-interacting protein isoform X1\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"119245992 RADX; RPA-related protein RADX isoform X1\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"119260451 RBM6; RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"119247210 XRCC6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"119256183 XRCC5; X-ray repair cross-complementing protein 5 isoform X1\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"119241502 PRKDC; DNA-dependent protein kinase catalytic subunit\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"119240393 MRE11; double-strand break repair protein MRE11 isoform X4\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"119243487 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"119259730 LIG4; DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"119261209 XRCC4; DNA repair protein XRCC4 isoform X2\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"119256223 NHEJ1; non-homologous end-joining factor 1 isoform X1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"119233545 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"119231206 POLM; DNA-directed DNA\/RNA polymerase mu\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"119233784 DNTT; DNA nucleotidylexotransferase\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"119257854 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"119230949 APTX; aprataxin isoform X2\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"119253332 aprataxin-like\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"119259023 APLF; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"119244709 DCLRE1C; protein artemis\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"119251694 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"119243162 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"119240502 PWWP3A; PWWP domain-containing DNA repair factor 3A\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"119245993 PWWP3B; PWWP domain-containing DNA repair factor 3B\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"119246414 PWWP domain-containing DNA repair factor 4-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"119246415 PWWP domain-containing DNA repair factor 4-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"119233003 PAXX; LOW QUALITY PROTEIN: protein PAXX\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"119247354 CYREN; cell cycle regulator of non-homologous end joining\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"119242400 JMJD8; jmjC domain-containing protein 8\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"119233519 SHLD2; shieldin complex subunit 2\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"119260601 BEND4; LOW QUALITY PROTEIN: BEN domain-containing protein 4\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"119235213 IFFO2; LOW QUALITY PROTEIN: intermediate filament family orphan 2\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"119247788 IFFO1; LOW QUALITY PROTEIN: non-homologous end joining factor IFFO1\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"119250285 FANCA; Fanconi anemia group A protein\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"119246326 FANCB; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"119250303 LOW QUALITY PROTEIN: Fanconi anemia group B protein-like\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"119232441 FANCC; Fanconi anemia group C protein isoform X1\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"119252379 FANCE; Fanconi anemia group E protein isoform X1\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"119255422 FANCF; Fanconi anemia group F protein\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"119232750 FANCG; Fanconi anemia group G protein\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"119258558 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"119239049 FANCM; Fanconi anemia group M protein isoform X1\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"119249212 FAAP24; Fanconi anemia core complex-associated protein 24 isoform X1\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"119232336 FAAP100; Fanconi anemia core complex-associated protein 100 isoform X1\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"119256797 HES1; transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"119237290 CENPS; centromere protein S\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"119234551 UBE2T; ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"119244243 BLM; recQ-like DNA helicase BLM\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"119230543 TOP3A; DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"119233454 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"119232985 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"119241930 RMI2; recQ-mediated genome instability protein 2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"119255462 FANCD2; Fanconi anemia group D2 protein\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"119244291 FANCI; Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"119230413 BRCA1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"119258825 BRCA2; breast cancer type 2 susceptibility protein isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"119230767 BRIP1; LOW QUALITY PROTEIN: Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"119241823 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"119244353 FAN1; fanconi-associated nuclease 1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"119238491 RAD51; DNA repair protein RAD51 homolog 1 isoform X1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"119231687 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"119242050 TELO2; telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"119237240 USP1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"119258185 WDR48; WD repeat-containing protein 48 isoform X2\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"119230667 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"119249754 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"119248161 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"119249884 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"119256909 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"119256062 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X2\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"119248056 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"119257425 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"119255042 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"119244374 HERC2; E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"119230676 WRAP53; telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"119232051 TPRN; taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"119241591 ZCWPW1; zinc finger CW-type PWWP domain protein 1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"119261175 WDR70; WD repeat-containing protein 70 isoform X1\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"119238562 WDR76; WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"119256196 HMCES; abasic site processing protein HMCES\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"119252502 POLH; DNA polymerase eta\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"119243029 POLI; DNA polymerase iota\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"119260894 POLK; DNA polymerase kappa isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"119259258 REV1; DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"119252787 REV3L; DNA polymerase zeta catalytic subunit isoform X2\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"119261367 POLN; DNA polymerase nu isoform X1\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"119245936 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"119243465 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"119255148 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X2\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"119257687 HLTF; helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"119234807 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 variant 2-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119236449 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119241480 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119249724 ubiquitin-conjugating enzyme E2 variant 2-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119258682 ubiquitin-conjugating enzyme E2 variant 2-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"119247433 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"119255165 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"119232790 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"119238731 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"119238724 PCLAF; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"119247370 PARPBP; PCNA-interacting partner isoform X1\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"119244605 SPRTN; DNA-dependent metalloprotease SPRTN\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"119246085 GCNA; germ cell nuclear acidic protein isoform X1\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"119253364 DPPA5; developmental pluripotency-associated 5 protein\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"119249913 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"119244994 RAD9B; cell cycle checkpoint control protein RAD9B isoform X1\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"119231540 HUS1; checkpoint protein HUS1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"119261378 RAD1; cell cycle checkpoint protein RAD1 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"119260203 RAD17; cell cycle checkpoint protein RAD17 isoform X1\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"119241504 RFC2; replication factor C subunit 2 isoform X2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"119257380 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"119244935 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"119258836 RFC3; LOW QUALITY PROTEIN: replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"119261378 RAD1; cell cycle checkpoint protein RAD1 isoform X1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"119248062 TIMELESS; protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"119238767 TIPIN; TIMELESS-interacting protein\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"119235829 CLSPN; LOW QUALITY PROTEIN: claspin\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"119242050 TELO2; telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"119232903 TTI1; TELO2-interacting protein 1 homolog isoform X1\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"119257796 TTI2; TELO2-interacting protein 2 isoform X1\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"119252204 BAG6; LOW QUALITY PROTEIN: large proline-rich protein BAG6\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"119236645 UBL4B; ubiquitin-like protein 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"119245784 UBL4A; ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"119241445 GET4; Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"119237258 INTS3; integrator complex subunit 3\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"119248054 NABP2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"119256046 NABP1; SOSS complex subunit B2 isoform X2\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"119231316 INIP; SOSS complex subunit C\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"119257701 ATR; serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"119259570 ATRIP; ATR-interacting protein\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"119259013 ETAA1; ewing's tumor-associated antigen 1 isoform X1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"119240886 ATM; serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"119230677 TP53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"119240818 CHEK1; serine\/threonine-protein kinase Chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"119244807 CHEK2; serine\/threonine-protein kinase Chk2\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"119259478 CDC25A; M-phase inducer phosphatase 1 isoform X1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"119235253 CDC25B; M-phase inducer phosphatase 2\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"119243428 CDC25C; M-phase inducer phosphatase 3 isoform X3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"119234735 LOW QUALITY PROTEIN: 14-3-3 protein theta-like\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"119235730 YWHAB; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"119238993 YWHAZ; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"119259564 YWHAQ; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"119241537 YWHAG; 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"119244870 YWHAH; 14-3-3 protein eta\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"119232973 YWHAE; 14-3-3 protein epsilon\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"119255432 NAV2; neuron navigator 2\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"119247861 WEE2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"119255461 WEE1; LOW QUALITY PROTEIN: wee1-like protein kinase\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"119230746 PER1; period circadian protein homolog 1 isoform X2\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"119252114 MDC1; mediator of DNA damage checkpoint protein 1 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"119245951 PLS3; plastin-3\tK17336 PLS3; plastin-3"
				},
				{
					"name":"119244300 AEN; apoptosis-enhancing nuclease isoform X1\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"119236492 PLK3; serine\/threonine-protein kinase PLK3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"119240361 PLK5; inactive serine\/threonine-protein kinase PLK5\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"119257965 NEK1; serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"119258537 LOW QUALITY PROTEIN: serine\/threonine-protein kinase Nek5-like\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"119258869 NEK5; serine\/threonine-protein kinase Nek5\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"119261250 NEK4; serine\/threonine-protein kinase Nek4 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"119237561 serine\/threonine-protein kinase Nek10\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"119256680 NEK11; serine\/threonine-protein kinase Nek11 isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"119257224 DONSON; protein downstream neighbor of Son\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"119232559 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"119237114 KANK4; KN motif and ankyrin repeat domain-containing protein 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"119240449 KANK3; KN motif and ankyrin repeat domain-containing protein 3 isoform X2\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"119240966 KANK2; KN motif and ankyrin repeat domain-containing protein 2\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"119240418 CHMP4C; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"119242992 VPS4B; vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"119249000 VPS4A; vacuolar protein sorting-associated protein 4A isoform X1\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"119238494 ZFYVE19; abscission\/NoCut checkpoint regulator\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"119244564 SDE2; splicing regulator SDE2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"119259150 KRCC1; lysine-rich coiled-coil protein 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				},
				{
					"name":"119232975 BLCAP; bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"119257479 POLQ; DNA polymerase theta isoform X1\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"119232978 MYBBP1A; myb-binding protein 1A\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"119257945 PRIMPOL; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"119259576 TREX1; three-prime repair exonuclease 1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"119246485 TREX2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"119233610 DCLRE1A; DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"119236346 DCLRE1B; 5' exonuclease Apollo\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"119236295 EXO5; exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"119232072 ENDOV; endonuclease V isoform X3\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"119255785 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 isoform X2\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"119242230 ANKLE1; ankyrin repeat and LEM domain-containing protein 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"119261161 HELQ; helicase POLQ-like isoform X1\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"119232675 ERCC6L2; DNA excision repair protein ERCC-6-like 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"119250132 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"119252523 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"119235358 pre-mRNA-splicing factor SPF27-like\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"119236373 pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"119233643 PLRG1; pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"119258913 NUDT15; nucleotide triphosphate diphosphatase NUDT15 isoform X1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"119241423 NUDT1; oxidized purine nucleoside triphosphate hydrolase isoform X1\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"119233428 NUDT18; 8-oxo-dGDP phosphatase NUDT18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"119238594 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"119246633 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"119255579 RRM1; ribonucleoside-diphosphate reductase large subunit isoform X1\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"119238943 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"119258685 RRM2; ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"119234131 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"119244883 UNG; uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"119247025 LOW QUALITY PROTEIN: uracil-DNA glycosylase-like\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"119248004 SMUG1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"119242405 MPG; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"119236175 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"119242031 NTHL1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"119247871 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"119247871 SSBP1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"119258913 NUDT15; nucleotide triphosphate diphosphatase NUDT15 isoform X1\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"119238594 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"119246633 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}
