{
	"name":"tpre01009",
	"children":[
	{
		"name":"Protein serine\/threonine phosphatases",
		"children":[
		{
			"name":"Phosphoprotein phosphatases (PPPs)",
			"children":[
			{
				"name":"Protein phosphatase-1",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106648928 serine\/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106654221 serine\/threonine-protein phosphatase alpha-2 isoform\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP1-interacting proteins (PIPs)",
					"children":[
					{
						"name":"106648827 protein phosphatase inhibitor 2-like\tK16833 PPP1R2; protein phosphatase inhibitor 2"
					},
					{
						"name":"106658413 protein phosphatase 1 regulatory subunit 3C-like isoform X1\tK07189 PPP1R3; protein phosphatase 1 regulatory subunit 3A\/B\/C\/D\/E"
					},
					{
						"name":"106650038 protein phosphatase 1 regulatory subunit 7-like\tK17550 PPP1R7; protein phosphatase 1 regulatory subunit 7"
					},
					{
						"name":"106652544 nuclear inhibitor of protein phosphatase 1\tK13216 PPP1R8; nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-]"
					},
					{
						"name":"106656674 serine\/threonine-protein phosphatase 1 regulatory subunit 10-like isoform X1\tK17552 PPP1R10; protein phosphatase 1 regulatory subunit 10"
					},
					{
						"name":"106648436 protein phosphatase 1 regulatory subunit 11\tK17553 PPP1R11; protein phosphatase 1 regulatory subunit 11"
					},
					{
						"name":"106648966 protein phosphatase 1 regulatory subunit 12A isoform X1\tK06270 PPP1R12A; protein phosphatase 1 regulatory subunit 12A"
					},
					{
						"name":"106657579 apoptosis-stimulating of p53 protein 2 isoform X3\tK17554 PPP1R13B; apoptosis-stimulating of p53 protein 1"
					},
					{
						"name":"106653698 protein phosphatase 1 regulatory subunit 14B\tK17555 PPP1R14B; protein phosphatase 1 regulatory subunit 14B"
					},
					{
						"name":"106657168 protein phosphatase 1 regulatory subunit 16A isoform X2\tK17458 PPP1R16A; protein phosphatase 1 regulatory subunit 16A"
					},
					{
						"name":"106660291 RNA polymerase II subunit 5-mediating protein homolog\tK17560 URI1; unconventional prefoldin RPB5 interactor 1"
					},
					{
						"name":"106652229 protein phosphatase 1 regulatory subunit 21\tK17562 PPP1R21; protein phosphatase 1 regulatory subunit 21"
					},
					{
						"name":"106655458 MICOS complex subunit mic25a\tK17563 CHCHD3; MICOS complex subunit MIC19"
					},
					{
						"name":"106650030 probable ATP-dependent RNA helicase DDX31\tK14806 DDX31; ATP-dependent RNA helicase DDX31\/DBP7 [EC:5.6.2.7]"
					},
					{
						"name":"106652915 brefeldin A-inhibited guanine nucleotide-exchange protein 3\tK17572 ARFGEF3; brefeldin A-inhibited guanine nucleotide-exchange protein 3"
					},
					{
						"name":"106648922 meiosis regulator and mRNA stability factor 1\tK17573 LKAP; meiosis arrest female protein 1"
					},
					{
						"name":"106653807 uncharacterized protein LOC106653807\tK17575 PPP1R36; protein phosphatase 1 regulatory subunit 36"
					},
					{
						"name":"106656746 protein phosphatase 1 regulatory subunit 37\tK17576 PPP1R37; protein phosphatase 1 regulatory subunit 37"
					},
					{
						"name":"106654245 SH3 domain-containing RING finger protein 3 isoform X1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
					},
					{
						"name":"106649034 protein phosphatase 1 regulatory subunit 42-like\tK17579 PPP1R42; protein phosphatase 1 regulatory subunit 42"
					},
					{
						"name":"106656061 A-kinase anchor protein 1, mitochondrial\tK16518 AKAP1; A-kinase anchor protein 1, mitochondrial"
					},
					{
						"name":"106655727 GSK3-beta interaction protein\tK28129 GSKIP; GSK3B-interacting protein"
					},
					{
						"name":"106654206 adenomatous polyposis coli homolog isoform X1\tK02085 APC; adenomatosis polyposis coli protein"
					},
					{
						"name":"106657646 aurora kinase C-like\tK11481 AURKA; aurora kinase A [EC:2.7.11.1]"
					},
					{
						"name":"106648989 aurora kinase B\tK11479 AURKB; aurora kinase B [EC:2.7.11.1]"
					},
					{
						"name":"106658029 axin isoform X1\tK02157 AXIN1; axin 1"
					},
					{
						"name":"106650747 uncharacterized protein LOC106650747\tK04570 BCL2L1; Bcl-2-like 1 (apoptosis regulator Bcl-X)"
					},
					{
						"name":"106656062 breast cancer type 1 susceptibility protein homolog isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"106653338 protein CASC1-like\tK17580 CASC1; cancer susceptibility candidate protein 1"
					},
					{
						"name":"106657348 CD2 antigen cytoplasmic tail-binding protein 2 homolog\tK13099 CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2"
					},
					{
						"name":"106649643 kinesin-related protein 4-like isoform X1\tK11498 CENPE; centromeric protein E"
					},
					{
						"name":"106652048 H(+)\/Cl(-) exchange transporter 7\tK05016 CLCN7; chloride channel 7"
					},
					{
						"name":"106659547 eukaryotic translation initiation factor 2 subunit 2 isoform X1\tK03238 EIF2S2; translation initiation factor 2 subunit 2"
					},
					{
						"name":"111694256 RNA polymerase II elongation factor ELL2-like\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"106658453 zinc finger FYVE domain-containing protein 9 isoform X2\tK04679 MADHIP; MAD, mothers against decapentaplegic interacting protein"
					},
					{
						"name":"106654450 endophilin-B1 isoform X1\tK11248 SH3GLB1; endophilin-B1"
					},
					{
						"name":"106659573 focal adhesion kinase 1 isoform X2\tK05725 PTK2; focal adhesion kinase 1 [EC:2.7.10.2]"
					},
					{
						"name":"106654081 tyrosine-protein kinase Fer isoform X1\tK08889 FER; tyrosine-protein kinase Fer [EC:2.7.10.2]"
					},
					{
						"name":"106660287 DNA polymerase delta subunit 3-like\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"106650765 glutaredoxin domain-containing cysteine-rich protein CG12206-like\tK17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1"
					},
					{
						"name":"106650595 host cell factor\tK14966 HCFC1; host cell factor 1"
					},
					{
						"name":"106657643 histone deacetylase 6 isoform X2\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
					},
					{
						"name":"106659907 inositol 1,4,5-trisphosphate receptor\tK04958 ITPR1; inositol 1,4,5-triphosphate receptor type 1"
					},
					{
						"name":"106655826 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
					},
					{
						"name":"106657101 S-adenosylhomocysteine hydrolase-like protein 1 isoform X1\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
					},
					{
						"name":"106657024 lysine-specific demethylase lid\tK11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]"
					},
					{
						"name":"106655531 60S ribosomal protein L5-like\tK02932 RP-L5e; large subunit ribosomal protein L5e"
					},
					{
						"name":"106656643 60S ribosomal protein L5-like\tK02932 RP-L5e; large subunit ribosomal protein L5e"
					},
					{
						"name":"106648410 uncharacterized protein LOC106648410 isoform X1\tK17480 AATK; lemur tyrosine kinase 1 [EC:2.7.10.1]"
					},
					{
						"name":"106659504 DNA replication licensing factor Mcm7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
					},
					{
						"name":"106659666 metabotropic glutamate receptor 1-like\tK04603 GRM1; metabotropic glutamate receptor 1"
					},
					{
						"name":"106648147 metabotropic glutamate receptor 7-like\tK04610 GRM8; metabotropic glutamate receptor 8"
					},
					{
						"name":"106649602 U3 small nucleolar ribonucleoprotein protein MPP10\tK14559 MPP10; U3 small nucleolar RNA-associated protein MPP10"
					},
					{
						"name":"106650144 myosin-IA\tK10356 MYO1; myosin I"
					},
					{
						"name":"106659899 unconventional myosin-Ie-like\tK10356 MYO1; myosin I"
					},
					{
						"name":"106653139 nuclear receptor corepressor 1 isoform X1\tK04650 NCOR1; nuclear receptor co-repressor 1"
					},
					{
						"name":"106648912 patronin isoform X2\tK17493 CAMSAP; calmodulin-regulated spectrin-associated protein"
					},
					{
						"name":"106652605 bumetanide-sensitive sodium-(potassium)-chloride cotransporter isoform X1\tK10951 SLC12A2; solute carrier family 12 (sodium\/potassium\/chloride transporter), member 2"
					},
					{
						"name":"106654077 bumetanide-sensitive sodium-(potassium)-chloride cotransporter\tK10951 SLC12A2; solute carrier family 12 (sodium\/potassium\/chloride transporter), member 2"
					},
					{
						"name":"106657459 nucleolar MIF4G domain-containing protein 1 homolog\tK17583 NOM1; nucleolar MIF4G domain-containing protein 1"
					},
					{
						"name":"106655541 origin recognition complex subunit 5\tK02607 ORC5; origin recognition complex subunit 5"
					},
					{
						"name":"106650120 phosphorylated CTD-interacting factor 1 isoform X1\tK17584 PCIF1; phosphorylated CTD-interacting factor 1"
					},
					{
						"name":"106653752 ATP-dependent 6-phosphofructokinase isoform X1\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"106648279 phosphatase and actin regulator 2-like isoform X1\tK17594 PHACTR; phosphatase and actin regulator"
					},
					{
						"name":"106650582 hrp65 protein-like\tK13219 SFPQ; splicing factor, proline- and glutamine-rich"
					},
					{
						"name":"106660204 RB1-inducible coiled-coil protein 1 isoform X1\tK17589 RB1CC1; RB1-inducible coiled-coil protein 1"
					},
					{
						"name":"106648513 ribosomal RNA processing protein 1 homolog\tK14849 RRP1; ribosomal RNA-processing protein 1"
					},
					{
						"name":"106654310 WW domain-binding protein 11\tK12866 WBP11; WW domain-binding protein 11"
					},
					{
						"name":"106655069 SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"106653492 probable cationic amino acid transporter\tK13871 SLC7A14; solute carrier family 7 (cationic amino acid transporter), member 14"
					},
					{
						"name":"106653202 sprouty-related, EVH1 domain-containing protein 1 isoform X1\tK04703 SPRED; sprouty-related, EVH1 domain-containing protein"
					},
					{
						"name":"106651695 double-stranded RNA-binding protein Staufen homolog isoform X1\tK17597 STAU; double-stranded RNA-binding protein Staufen"
					},
					{
						"name":"106657124 microtubule-associated protein tau-like isoform X1\tK04380 MAPT; microtubule-associated protein tau"
					},
					{
						"name":"106658961 transmembrane protein 132B\tK17599 TMEM132; transmembrane protein 132"
					},
					{
						"name":"106653185 transformer-2 protein homolog alpha isoform X2\tK12897 TRA2; transformer-2 protein"
					},
					{
						"name":"106648369 tuberin\tK07207 TSC2; tuberous sclerosis 2"
					},
					{
						"name":"106652119 protein starmaker-like\tK17492 UBN; ubinuclein"
					},
					{
						"name":"106648673 vacuolar protein sorting-associated protein 54\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
					},
					{
						"name":"106657317 WD repeat-containing protein 81 isoform X1\tK17601 WDR81; WD repeat-containing protein 81"
					},
					{
						"name":"106657801 uncharacterized protein LOC106657801 isoform X1\tK08867 WNK; WNK lysine deficient protein kinase [EC:2.7.11.1]"
					},
					{
						"name":"106648980 uncharacterized protein LOC106648980 isoform X1\tK17602 YLPM1; YLP motif-containing protein 1"
					},
					{
						"name":"106648007 zinc finger FYVE domain-containing protein 1-like\tK17603 ZFYVE1; zinc finger FYVE domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-2 (PP2A)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106658269 serine\/threonine-protein phosphatase 2A catalytic subunit alpha isoform\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"106648616 serine\/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform isoform X1\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"106658991 serine\/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"106648660 uncharacterized protein LOC106648660 isoform X1\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"106656631 serine\/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma-like\tK11583 PPP2R3; serine\/threonine-protein phosphatase 2A regulatory subunit B''"
					},
					{
						"name":"106652316 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform-like\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					},
					{
						"name":"106659396 serine\/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other PP2-interacting proteins",
					"children":[
					{
						"name":"106658249 serine\/threonine-protein phosphatase 2A activator-like\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"106658369 immunoglobulin-binding protein 1b\tK17606 IGBP1; immunoglobulin-binding protein 1"
					},
					{
						"name":"106651199 TIP41-like protein\tK17607 TIPRL; type 2A phosphatase activator TIP41"
					},
					{
						"name":"106657314 striatin\tK17608 STRN1_3_4; striatin 1\/3\/4"
					},
					{
						"name":"106655790 striatin-interacting protein 1\tK27960 STRIP; striatin-interacting protein"
					},
					{
						"name":"106656791 MOB kinase activator-like 4\tK27961 MOB4; MOB-like protein phocein"
					},
					{
						"name":"106649490 uncharacterized protein CG10915\tK27962 CTTNBP2NL; CTTNBP2 N-terminal-like protein"
					},
					{
						"name":"106659275 sarcolemmal membrane-associated protein\tK27963 SLMAP; sarcolemmal membrane-associated protein"
					},
					{
						"name":"106650648 nucleoredoxin-like\tK17609 NXN; nucleoredoxin [EC:1.8.1.8]"
					},
					{
						"name":"106659459 leucine carboxyl methyltransferase 1\tK18203 LCMT1; [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233]"
					},
					{
						"name":"106651934 alpha-endosulfine\tK27491 ENSA; endosulfine family protein"
					}
					]
				}
				]
			},
			{
				"name":"Calcineurin (PPP3\/ PP2B)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106648831 serine\/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X2\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106652049 serine\/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106655179 serine\/threonine-protein phosphatase 2B catalytic subunit 3-like isoform X3\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"106655750 serine\/threonine-protein phosphatase 2B catalytic subunit alpha isoform-like isoform X1\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"106660541 calcineurin subunit B type 2\tK06268 PPP3R; serine\/threonine-protein phosphatase 2B regulatory subunit"
					},
					{
						"name":"106650908 calmodulin-like isoform X1\tK02183 CALM; calmodulin"
					},
					{
						"name":"106657562 calmodulin-like protein 4\tK02183 CALM; calmodulin"
					},
					{
						"name":"106659299 calmodulin isoform X2\tK02183 CALM; calmodulin"
					},
					{
						"name":"106660403 calcineurin B homologous protein 1\tK17610 CHP; calcineurin B homologous protein 1"
					}
					]
				},
				{
					"name":"Other calcineurin-interacting proteins",
					"children":[
					{
						"name":"106658188 calcineurin-binding protein cabin-1-like\tK17613 CABIN1; calcineurin-binding protein cabin-1"
					},
					{
						"name":"106659780 peptidyl-prolyl cis-trans isomerase FKBP8\tK09574 FKBP8; FK506-binding protein 8 [EC:5.2.1.8]"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-4",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106656906 serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"106652122 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"106660537 serine\/threonine-protein phosphatase 4 regulatory subunit 2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"106652300 serine\/threonine-protein phosphatase 4 regulatory subunit 3 isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"106656727 serine\/threonine-protein phosphatase 4 regulatory subunit 4-like isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-5",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106659520 serine\/threonine-protein phosphatase 5\tK04460 PPP5C; serine\/threonine-protein phosphatase 5 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP5-interacting proteins",
					"children":[
					{
						"name":"106655873 cell division cycle protein 27 homolog\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"106656029 cell division cycle protein 16 homolog\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"106650483 heat shock protein 83\tK04079 HSP90A; molecular chaperone HtpG"
					},
					{
						"name":"106648008 heat shock 70 kDa protein cognate 4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"106656683 heat shock protein 68-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"106659289 heat shock 70 kDa protein cognate 4-like\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-6",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"106654897 serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"106652869 serine\/threonine-protein phosphatase 6 regulatory subunit 3\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					}
					]
				}
				]
			},
			{
				"name":"PPEF\/PP7 protein phosphatases"
			}
			]
		},
		{
			"name":"Mg2+- or Mn2+- dependent protein phosphatases (PPMs)",
			"children":[
			{
				"name":"PPM1 phosphatases (PP2C)",
				"children":[
				{
					"name":"106652289 protein phosphatase 1B-like\tK04461 PPM1B; protein phosphatase 1B [EC:3.1.3.16]"
				},
				{
					"name":"106655776 probable protein phosphatase CG10417\tK17499 PPM1G; protein phosphatase 1G [EC:3.1.3.16]"
				},
				{
					"name":"106652435 uncharacterized protein LOC106652435\tK10147 PPM1D; protein phosphatase 1D [EC:3.1.3.16]"
				},
				{
					"name":"106659958 protein phosphatase 1H\tK17503 PPM1H; protein phosphatase 1H [EC:3.1.3.16]"
				},
				{
					"name":"106649933 protein phosphatase PHLPP-like protein\tK16340 PHLPP; PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16]"
				},
				{
					"name":"106659896 probable protein phosphatase 2C T23F11.1\tK14803 PTC2_3; protein phosphatase PTC2\/3 [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"Pyruvate dehydrogenase phosphatases",
				"children":[
				{
					"name":"Catalytic subunit",
					"children":[
					{
						"name":"106659375 pyruvate dehydrogenase [acetyl-transferring]-phosphatase 1, mitochondrial\tK01102 PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]"
					}
					]
				},
				{
					"name":"Regulatory subunit",
					"children":[
					{
						"name":"106648951 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial\tK17509 PDPR; pyruvate dehydrogenase phosphatase regulatory subunit"
					},
					{
						"name":"106658335 pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial-like\tK17509 PDPR; pyruvate dehydrogenase phosphatase regulatory subunit"
					}
					]
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein tyrosine phosphatases (PTPs)",
		"children":[
		{
			"name":"Class I PTPs (Classical)",
			"children":[
			{
				"name":"Receptor PTPs",
				"children":[
				{
					"name":"106650553 tyrosine-protein phosphatase 10D isoform X1\tK05694 PTPRB; receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48]"
				},
				{
					"name":"106650532 tyrosine-protein phosphatase Lar isoform X2\tK05695 PTPRF; receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48]"
				},
				{
					"name":"106650331 uncharacterized protein LOC106650331 isoform X1\tK07817 PTPRN; receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48]"
				},
				{
					"name":"106656926 tyrosine-protein phosphatase non-receptor type 5-like isoform X1\tK04458 PTPRR; receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"Non-receptor PTPs",
				"children":[
				{
					"name":"106652129 tyrosine-protein phosphatase non-receptor type 2 isoform X2\tK18026 PTPN2; tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48]"
				},
				{
					"name":"106657401 tyrosine-protein phosphatase non-receptor type 4 isoform X1\tK18037 PTPN4; tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48]"
				},
				{
					"name":"106654172 tyrosine-protein phosphatase non-receptor type 9\tK18038 PTPN9; tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48]"
				},
				{
					"name":"106648937 tyrosine-protein phosphatase corkscrew isoform X1\tK07293 PTPN11; tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class I PTPs (Dual specificity phosphatases)",
			"children":[
			{
				"name":"MAPK phosphatases",
				"children":[
				{
					"name":"106653699 dual specificity protein phosphatase Mpk3-like isoform X1\tK04459 DUSP2S; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Slingshots",
				"children":[
				{
					"name":"106649319 uncharacterized protein LOC106649319 isoform X1\tK05766 SSH; protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Phosphatase of regenerating liver (PRL)",
				"children":[
				{
					"name":"106651474 protein tyrosine phosphatase type IVA 1\tK18041 PTP4A; protein tyrosine phosphatase type IVA [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"Atypical DSPs",
				"children":[
				{
					"name":"106652747 dual specificity protein phosphatase MPK-4-like\tK14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"106652290 phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 isoform X1\tK14165 K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"106655836 RNA\/RNP complex-1-interacting phosphatase-like isoform X1\tK14165 K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"106657187 dual specificity protein phosphatase 15-like\tK14165 K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"106658179 dual specificity protein phosphatase 3-like isoform X1\tK14165 K14165; atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"106651738 serine\/threonine\/tyrosine-interacting protein-like\tK18042 STYX; serine\/threonine\/tyrosine-interacting protein"
				}
				]
			},
			{
				"name":"CDC14",
				"children":[
				{
					"name":"106659294 dual specificity protein phosphatase CDC14B isoform X1\tK06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Phosphatase and Tensin homologs (PTEN)",
				"children":[
				{
					"name":"106650074 phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN isoform X1\tK01110 PTEN; phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]"
				},
				{
					"name":"106650961 tensin-1-like isoform X1\tK18080 TNS; tensin"
				},
				{
					"name":"106654995 tensin-1 isoform X1\tK18080 TNS; tensin"
				}
				]
			},
			{
				"name":"Myotubularins",
				"children":[
				{
					"name":"106655585 myotubularin-related protein 2 isoform X1\tK18081 MTMR1_2; myotubularin-related protein 1\/2 [EC:3.1.3.64 3.1.3.95]"
				},
				{
					"name":"106654902 myotubularin-related protein 3\tK18082 MTMR3_4; myotubularin-related protein 3\/4 [EC:3.1.3.48 3.1.3.64 3.1.3.95]"
				},
				{
					"name":"106650960 myotubularin-related protein 13\tK18061 SBF1_2; myotubularin-related protein 5\/13"
				},
				{
					"name":"106657695 myotubularin-related protein 6\tK18083 MTMR6_7_8; myotubularin-related protein 6\/7\/8 [EC:3.1.3.64 3.1.3.95]"
				},
				{
					"name":"106648605 myotubularin-related protein 9\tK18084 MTMR9; myotubularin-related protein 9"
				},
				{
					"name":"106648521 myotubularin-related protein 10-B\tK18085 MTMR10_11_12; myotubularin-related protein 10\/11\/12"
				},
				{
					"name":"106657851 myotubularin-related protein 14\tK18086 MTMR14; myotubularin-related protein 14 [EC:3.1.3.64 3.1.3.95]"
				}
				]
			},
			{
				"name":"Suppressors of T-cell receptor signaling"
			}
			]
		},
		{
			"name":"Class II PTPs",
			"children":[
			{
				"name":"Low molecular weight PTPs (LMWPTPs)",
				"children":[
				{
					"name":"106659830 low molecular weight phosphotyrosine protein phosphatase-like\tK14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]"
				},
				{
					"name":"106659889 low molecular weight phosphotyrosine protein phosphatase-like\tK14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class III PTPs",
			"children":[
			{
				"name":"CDC25s",
				"children":[
				{
					"name":"106651124 M-phase inducer phosphatase-like isoform X1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"HAD phosphatases",
		"children":[
		{
			"name":"Fcp\/Scp phosphatases",
			"children":[
			{
				"name":"106654664 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"106659775 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1-like isoform X2\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"106649989 CTD small phosphatase-like protein 2 isoform X1\tK17616 CTDSPL2; CTD small phosphatase-like protein 2 [EC:3.1.3.-]"
			},
			{
				"name":"106653148 CTD nuclear envelope phosphatase 1 homolog isoform X1\tK17617 CTDNEP1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]"
			},
			{
				"name":"106654646 ubiquitin-like domain-containing CTD phosphatase 1\tK17618 UBLCP1; ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16]"
			},
			{
				"name":"106655215 putative RNA polymerase II subunit B1 CTD phosphatase RPAP2\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
			}
			]
		},
		{
			"name":"MDP-1",
			"children":[
			{
				"name":"106659358 magnesium-dependent phosphatase 1-like\tK17619 MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]"
			}
			]
		},
		{
			"name":"EYAs",
			"children":[
			{
				"name":"106655699 eyes absent homolog 2 isoform X2\tK17622 EYA4; eyes absent homolog 4 [EC:3.1.3.48]"
			}
			]
		},
		{
			"name":"Other HAD phosphatases",
			"children":[
			{
				"name":"106650393 glycerol-3-phosphate phosphatase-like\tK19269 PGP; phosphoglycolate phosphatase [EC:3.1.3.18 3.1.3.48]"
			},
			{
				"name":"106658062 uncharacterized protein F21D5.5 isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
			},
			{
				"name":"106654864 phosphoserine phosphatase isoform X1\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]"
			},
			{
				"name":"106651562 pseudouridine-5'-phosphatase-like\tK17623 PUDP; pseudouridine 5'-phosphatase [EC:3.1.3.96]"
			},
			{
				"name":"106651563 pseudouridine-5'-phosphatase-like isoform X1\tK17623 PUDP; pseudouridine 5'-phosphatase [EC:3.1.3.96]"
			},
			{
				"name":"106652293 N-acylneuraminate-9-phosphatase\tK01097 NANP; N-acylneuraminate-9-phosphatase [EC:3.1.3.29]"
			},
			{
				"name":"106651757 phosphatidate phosphatase LPIN3 isoform X1\tK15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]"
			}
			]
		}
		]
	}
	]
}