{
	"name":"tsco03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"R1T40_19070 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"R1T40_19075 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"R1T40_05905 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"R1T40_04010 dksA; RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"R1T40_16455 nusA; transcription termination factor NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"R1T40_10215 nusB; transcription antitermination factor NusB\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"R1T40_08550 hypothetical protein\tK02601 nusG; transcription termination\/antitermination protein NusG"
			},
			{
				"name":"R1T40_14435 nusG; transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"R1T40_04275 rsmA; 16S rRNA (adenine(1518)-N(6)\/adenine(1519)-N(6))-dimethyltransferase RsmA\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"R1T40_05555 RsmB\/NOP family class I SAM-dependent RNA methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"R1T40_15185 transcription antitermination factor NusB\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"R1T40_13220 class I SAM-dependent methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"R1T40_13640 rsmD; 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"R1T40_13115 16S rRNA (uracil(1498)-N(3))-methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"R1T40_16230 rsmG; 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"R1T40_02165 rsmH; 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"R1T40_20340 rsmI; 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"R1T40_02000 rlmB; 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"R1T40_05955 RlmE family RNA methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"R1T40_13815 rlmH; 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"R1T40_03960 class I SAM-dependent rRNA methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"R1T40_20470 rlmJ; 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"R1T40_16715 rlmN; 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"R1T40_16375 class I SAM-dependent RNA methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"R1T40_15270 RluA family pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"R1T40_08300 pseudouridine synthase\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"R1T40_14125 RluA family pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"R1T40_10165 RluA family pseudouridine synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"R1T40_06070 pseudouridine synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"R1T40_12590 GNAT family N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"R1T40_11100 GNAT family protein\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"R1T40_03000 rimK; 30S ribosomal protein S6--L-glutamate ligase\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"R1T40_18705 GAK system ATP-grasp enzyme\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"R1T40_18815 rimM; ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"R1T40_09210 rimO; 30S ribosomal protein S12 methylthiotransferase RimO\tK14441 rimO; ribosomal protein S12 methylthiotransferase [EC:2.8.4.4]"
			},
			{
				"name":"R1T40_11360 50S ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"R1T40_19070 rnc; ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"R1T40_04650 Rne\/Rng family ribonuclease\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"R1T40_07035 ruvX; Holliday junction resolvase RuvX\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"R1T40_09470 DEAD\/DEAH box helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"R1T40_19075 era; GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"R1T40_00980 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"R1T40_01460 rsgA; ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"R1T40_06935 der; ribosome biogenesis GTPase Der\tK03977 engA; GTPase"
			},
			{
				"name":"R1T40_05905 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"R1T40_05205 hflX; GTPase HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"R1T40_13015 L-threonylcarbamoyladenylate synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"R1T40_19040 bifunctional (p)ppGpp synthetase\/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"R1T40_15200 rbfA; 30S ribosome-binding factor RbfA\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"R1T40_16450 rimP; ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"R1T40_13820 rsfS; ribosome silencing factor\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"R1T40_12165 ybeY; rRNA maturation RNase YbeY\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"R1T40_15690 raiA; ribosome-associated translation inhibitor RaiA\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"R1T40_12005 ychF; redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}