{
	"name":"twi01002",
	"children":[
	{
		"name":"Aspartic peptidases",
		"children":[
		{
			"name":"Family A1: pepsin family"
		},
		{
			"name":"Family A2: retropepsin family"
		},
		{
			"name":"Family A5: thermopsin family"
		},
		{
			"name":"Family A8: signal peptidase II family",
			"children":[
			{
				"name":"Thewi_1489 Lipoprotein signal peptidase\tK03101 lspA; signal peptidase II [EC:3.4.23.36]"
			}
			]
		},
		{
			"name":"Family A22: presenilin family"
		},
		{
			"name":"Family A24: type IV prepilin peptidase family",
			"children":[
			{
				"name":"Thewi_1215 peptidase A24A domain protein\tK02654 pilD; leader peptidase (prepilin peptidase) \/ N-methyltransferase [EC:3.4.23.43 2.1.1.-]"
			}
			]
		},
		{
			"name":"Family A25: gpr protease family",
			"children":[
			{
				"name":"Thewi_1034 Germination protease\tK06012 gpr; spore protease [EC:3.4.24.78]"
			}
			]
		},
		{
			"name":"Family A26: omptin family"
		},
		{
			"name":"Family A28"
		},
		{
			"name":"Family A31: HybD endopeptidase family"
		},
		{
			"name":"Family A36",
			"children":[
			{
				"name":"Thewi_1597 hypothetical protein\tK06383 spoIIGA; stage II sporulation protein GA (sporulation sigma-E factor processing peptidase) [EC:3.4.23.-]"
			}
			]
		}
		]
	},
	{
		"name":"Cysteine peptidases",
		"children":[
		{
			"name":"Family C1: papain family"
		},
		{
			"name":"Family C2: calpain family"
		},
		{
			"name":"Family C3: picornain family"
		},
		{
			"name":"Family C4: NIa protease family"
		},
		{
			"name":"Family C5"
		},
		{
			"name":"Family C9"
		},
		{
			"name":"Family C10: streptopain family"
		},
		{
			"name":"Family C11: clostripain family"
		},
		{
			"name":"Family C12: ubiquitin C-terminal hydrolase family"
		},
		{
			"name":"Family C13: legumain family"
		},
		{
			"name":"Family C14: caspase family"
		},
		{
			"name":"Family C15: pyroglutamyl peptidase I family",
			"children":[
			{
				"name":"Thewi_1072 Pyrrolidone-carboxylate peptidase\tK01304 PGPEP1; pyroglutamyl-peptidase [EC:3.4.19.3]"
			}
			]
		},
		{
			"name":"Family C16"
		},
		{
			"name":"Family C19: ubiquitin-specific protease family"
		},
		{
			"name":"Family C25: gingipain family"
		},
		{
			"name":"Family C26: gamma-glutamyl hydrolase family",
			"children":[
			{
				"name":"Thewi_0667 GMP synthase (glutamine-hydrolyzing)\tK01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]"
			}
			]
		},
		{
			"name":"Family C27"
		},
		{
			"name":"Family C30"
		},
		{
			"name":"Family C37"
		},
		{
			"name":"Family C39"
		},
		{
			"name":"Family C40"
		},
		{
			"name":"Family C44",
			"children":[
			{
				"name":"Thewi_0674 amidophosphoribosyltransferase\tK00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]"
			},
			{
				"name":"Thewi_0369 sugar isomerase (SIS)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
			},
			{
				"name":"Thewi_2175 Glucosamine--fructose-6-phosphate aminotransferase (isomerizing)\tK00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]"
			},
			{
				"name":"Thewi_0579 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
			},
			{
				"name":"Thewi_1014 asparagine synthase (glutamine-hydrolyzing)\tK01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]"
			}
			]
		},
		{
			"name":"Family C45"
		},
		{
			"name":"Family C46: hedgehog family"
		},
		{
			"name":"Family C47: staphopain family"
		},
		{
			"name":"Family C48: Ulp1 endopeptidase family"
		},
		{
			"name":"Family C50: separase family"
		},
		{
			"name":"Family C54: Aut2 peptidase family"
		},
		{
			"name":"Family C55: YopJ protease family"
		},
		{
			"name":"Family C56: PfpI endopeptidase family",
			"children":[
			{
				"name":"Thewi_1075 intracellular protease, PfpI family\tK05520 yhbO; deglycase [EC:3.5.1.124]"
			}
			]
		},
		{
			"name":"Family C57: vaccinia virus I7 peptidase family"
		},
		{
			"name":"Family C58"
		},
		{
			"name":"Family C59"
		},
		{
			"name":"Family C60"
		},
		{
			"name":"Family C63"
		},
		{
			"name":"Family C64"
		},
		{
			"name":"Family C65"
		},
		{
			"name":"Family C67"
		},
		{
			"name":"Family C69"
		},
		{
			"name":"Family C70"
		},
		{
			"name":"Family C75",
			"children":[
			{
				"name":"Thewi_0641 Accessory gene regulator B\tK07813 agrB; accessory gene regulator B"
			}
			]
		},
		{
			"name":"Family C76"
		},
		{
			"name":"Family C78"
		},
		{
			"name":"Family C79"
		},
		{
			"name":"Family C82"
		},
		{
			"name":"Family C83"
		},
		{
			"name":"Family C85"
		},
		{
			"name":"Family C86"
		},
		{
			"name":"Family C88"
		},
		{
			"name":"Family C89"
		},
		{
			"name":"Family C97"
		},
		{
			"name":"Family C98"
		},
		{
			"name":"Family C110"
		}
		]
	},
	{
		"name":"Glutamic peptidases",
		"children":[
		{
			"name":"Family G1"
		},
		{
			"name":"Family G4"
		},
		{
			"name":"Family G5: prenyl protease 2 family",
			"children":[
			{
				"name":"Thewi_2583 Abortive infection protein\tK07052 K07052; CAAX protease family protein"
			}
			]
		}
		]
	},
	{
		"name":"Metallo peptidases",
		"children":[
		{
			"name":"Family M1"
		},
		{
			"name":"Family M2"
		},
		{
			"name":"Family M3",
			"children":[
			{
				"name":"Thewi_1104 oligoendopeptidase F\tK08602 pepF; oligoendopeptidase F [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M4: thermolysin family"
		},
		{
			"name":"Family M5: mycolysin family"
		},
		{
			"name":"Family M6: immune inhibitor A family"
		},
		{
			"name":"Family M7: snapalysin family"
		},
		{
			"name":"Family M8: leishmanolysin family"
		},
		{
			"name":"Family M9"
		},
		{
			"name":"Family M10"
		},
		{
			"name":"Family M12: astacin\/adamalysin family"
		},
		{
			"name":"Family M13: neprilysin family"
		},
		{
			"name":"Family M14: carboxypeptidase A family"
		},
		{
			"name":"Family M15: zinc D-Ala-D-Ala carboxypeptidase family"
		},
		{
			"name":"Family M16: pitrilysin family"
		},
		{
			"name":"Family M17: leucyl aminopeptidase family"
		},
		{
			"name":"Family M18"
		},
		{
			"name":"Family M19: membrane dipeptidase family",
			"children":[
			{
				"name":"Thewi_2025 peptidase M19 renal dipeptidase\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			}
			]
		},
		{
			"name":"Family M20",
			"children":[
			{
				"name":"Thewi_1675 dipeptidase\tK01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]"
			},
			{
				"name":"Thewi_1771 peptidase T\tK01258 pepT; tripeptide aminopeptidase [EC:3.4.11.4]"
			}
			]
		},
		{
			"name":"Family M23"
		},
		{
			"name":"Family M24",
			"children":[
			{
				"name":"Thewi_2234 methionine aminopeptidase, type I\tK01265 map; methionyl aminopeptidase [EC:3.4.11.18]"
			},
			{
				"name":"Thewi_1229 peptidase M24\tK01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]"
			}
			]
		},
		{
			"name":"Family M26"
		},
		{
			"name":"Family M27"
		},
		{
			"name":"Family M28: aminopeptidase Y family"
		},
		{
			"name":"Family M29: aminopeptidase T family"
		},
		{
			"name":"Family M32: carboxypeptidase Taq family"
		},
		{
			"name":"Family M34: anthrax lethal factor family"
		},
		{
			"name":"Family M35: deuterolysin family"
		},
		{
			"name":"Family M36: fungalysin family"
		},
		{
			"name":"Family M38: beta-aspartyl dipeptidase family",
			"children":[
			{
				"name":"Thewi_0924 isoaspartyl dipeptidase\tK01305 iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]"
			}
			]
		},
		{
			"name":"Family M41: FtsH endopeptidase family",
			"children":[
			{
				"name":"Thewi_0133 AAA ATPase central domain protein\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			},
			{
				"name":"Thewi_1995 ATP-dependent metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			},
			{
				"name":"Thewi_2334 ATP-dependent metalloprotease FtsH\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M42: glutamyl aminopeptidase family"
		},
		{
			"name":"Family M43: cytophagalysin family"
		},
		{
			"name":"Family M44"
		},
		{
			"name":"Family M48: Ste24 endopeptidase family",
			"children":[
			{
				"name":"Thewi_0827 hypothetical protein\tK03799 htpX; heat shock protein HtpX [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M49: dipeptidyl-peptidase III family"
		},
		{
			"name":"Family M50: S2P protease family",
			"children":[
			{
				"name":"Thewi_0994 peptidase M50\tK06402 spoIVFB; stage IV sporulation protein FB [EC:3.4.24.-]"
			},
			{
				"name":"Thewi_1357 membrane-associated zinc metalloprotease\tK11749 rseP; regulator of sigma E protease [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"Family M54"
		},
		{
			"name":"Family M55: DppA aminopeptidase family"
		},
		{
			"name":"Family M56"
		},
		{
			"name":"Family M67"
		},
		{
			"name":"Family M72"
		},
		{
			"name":"Family M73"
		},
		{
			"name":"Family M74"
		},
		{
			"name":"Family M80"
		},
		{
			"name":"Family M82"
		},
		{
			"name":"Family M85"
		},
		{
			"name":"Family M88"
		},
		{
			"name":"Family M90"
		},
		{
			"name":"Family M98"
		}
		]
	},
	{
		"name":"Asparagine peptide lyases",
		"children":[
		{
			"name":"Family N1"
		},
		{
			"name":"Family N8"
		}
		]
	},
	{
		"name":"Mixed peptidases",
		"children":[
		{
			"name":"Family P1: DmpA aminopeptidase family"
		},
		{
			"name":"Family P2"
		}
		]
	},
	{
		"name":"Serine peptidases",
		"children":[
		{
			"name":"Family S1: chymotrypsin family",
			"children":[
			{
				"name":"Thewi_2574 peptidase S1 and S6 chymotrypsin\/Hap\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			}
			]
		},
		{
			"name":"Family S3: togavirin family"
		},
		{
			"name":"Family S6"
		},
		{
			"name":"Family S7: flavivirin family"
		},
		{
			"name":"Family S8: subtilisin family",
			"children":[
			{
				"name":"Thewi_0649 peptidase S8 and S53 subtilisin kexin sedolisin\tK17734 aprX; serine protease AprX [EC:3.4.21.-]"
			},
			{
				"name":"Thewi_0908 peptidase S8 and S53 subtilisin kexin sedolisin\tK17734 aprX; serine protease AprX [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S9: prolyl oligopeptidase family"
		},
		{
			"name":"Family S10"
		},
		{
			"name":"Family S11: D-Ala-D-Ala carboxypeptidase A family",
			"children":[
			{
				"name":"Thewi_1015 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"Thewi_1264 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			},
			{
				"name":"Thewi_1282 peptidase S11 D-alanyl-D-alanine carboxypeptidase 1\tK07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5\/6) [EC:3.4.16.4]"
			}
			]
		},
		{
			"name":"Family S12: D-Ala-D-Ala carboxypeptidase B family"
		},
		{
			"name":"Family S13: D-Ala-D-Ala peptidase C family"
		},
		{
			"name":"Family S14: ClpP endopeptidase family",
			"children":[
			{
				"name":"Thewi_0740 ATP-dependent Clp protease proteolytic subunit\tK01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]"
			}
			]
		},
		{
			"name":"Family S15"
		},
		{
			"name":"Family S16: lon protease family",
			"children":[
			{
				"name":"Thewi_0742 anti-sigma H sporulation factor, LonB\tK01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]"
			}
			]
		},
		{
			"name":"Family S21: assemblin family"
		},
		{
			"name":"Family S24: LexA family"
		},
		{
			"name":"Family S26: signal peptidase I family",
			"children":[
			{
				"name":"Thewi_0027 signal peptidase I\tK03100 lepB; signal peptidase I [EC:3.4.21.89]"
			}
			]
		},
		{
			"name":"Family S28"
		},
		{
			"name":"Family S31"
		},
		{
			"name":"Family S32"
		},
		{
			"name":"Family S33"
		},
		{
			"name":"Family S41: C-terminal processing peptidase family",
			"children":[
			{
				"name":"Thewi_1946 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
			},
			{
				"name":"Thewi_2604 carboxyl-terminal protease\tK03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]"
			}
			]
		},
		{
			"name":"Family S45"
		},
		{
			"name":"Family S49: protease IV family",
			"children":[
			{
				"name":"Thewi_0937 signal peptide peptidase SppA, 36K type\tK04773 sppA; protease IV [EC:3.4.21.-]"
			}
			]
		},
		{
			"name":"Family S50"
		},
		{
			"name":"Family S51",
			"children":[
			{
				"name":"Thewi_2620 peptidase S51 dipeptidase E\tK05995 pepE; dipeptidase E [EC:3.4.13.21]"
			},
			{
				"name":"Thewi_2709 cyanophycinase\tK13282 cphB; cyanophycinase [EC:3.4.15.6]"
			}
			]
		},
		{
			"name":"Family S53"
		},
		{
			"name":"Family S54: Rhomboid family",
			"children":[
			{
				"name":"Thewi_0466 Rhomboid family protein\tK07059 rho2; rhomboid family protease [EC:3.4.21.105]"
			}
			]
		},
		{
			"name":"Family S55: SpoIVB peptidase family",
			"children":[
			{
				"name":"Thewi_1252 stage IV sporulation protein B\tK06399 spoIVB; stage IV sporulation protein B [EC:3.4.21.116]"
			}
			]
		},
		{
			"name":"Family S62"
		},
		{
			"name":"Family S66"
		},
		{
			"name":"Family S77: phage prohead processing peptidase family"
		},
		{
			"name":"Family S78"
		}
		]
	},
	{
		"name":"Threonine peptidases",
		"children":[
		{
			"name":"Family T1: proteasome family",
			"children":[
			{
				"name":"Thewi_1403 ATP-dependent protease hslV\tK01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]"
			}
			]
		},
		{
			"name":"Family T2"
		},
		{
			"name":"Family T3: gamma-glutamyltransferase family"
		}
		]
	},
	{
		"name":"Peptidases of unknown catalytic type",
		"children":[
		{
			"name":"Family U32",
			"children":[
			{
				"name":"Thewi_1206 peptidase U32\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
			},
			{
				"name":"Thewi_1647 peptidase U32\tK08303 prtC; U32 family peptidase [EC:3.4.-.-]"
			}
			]
		},
		{
			"name":"Family U62"
		}
		]
	},
	{
		"name":"Peptidase inhibitors",
		"children":[
		{
			"name":"Family I1: Kazal family"
		},
		{
			"name":"Family I2: Kunitz - BPTI family"
		},
		{
			"name":"Family I4: serpin family"
		},
		{
			"name":"Family I11: ecotin family"
		},
		{
			"name":"Family I17: WAP-type family"
		},
		{
			"name":"Family I25: cystatin family"
		},
		{
			"name":"Family I27: calpastatin family"
		},
		{
			"name":"Family I32: IAP family"
		},
		{
			"name":"Family I34: IA3 family"
		},
		{
			"name":"Family I35: timp family"
		},
		{
			"name":"Family I39: alpha2M family"
		},
		{
			"name":"Family I47: latexin family"
		},
		{
			"name":"Family I49: proSAAS family"
		},
		{
			"name":"Family I51: IC family"
		},
		{
			"name":"Family I57: staphostatin B family"
		},
		{
			"name":"Family I63"
		},
		{
			"name":"Family I80"
		},
		{
			"name":"Family I87"
		},
		{
			"name":"Family I93"
		}
		]
	}
	]
}