{
	"name":"ure04147",
	"children":[
	{
		"name":"Exosomal proteins",
		"children":[
		{
			"name":"Proteins found in most exosomes",
			"children":[
			{
				"name":"UREG_04106 hypothetical protein\tK05765 CFL; cofilin"
			},
			{
				"name":"UREG_05232 dynein heavy chain\tK10413 DYNC1H; dynein cytoplasmic 1 heavy chain"
			},
			{
				"name":"UREG_02713 myosin-5\tK10356 MYO1; myosin I"
			},
			{
				"name":"UREG_02803 profilin-2\tK05759 PFN; profilin"
			},
			{
				"name":"UREG_01466 heat shock protein SSB1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"UREG_03219 heat shock 70 kDa protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
			},
			{
				"name":"UREG_01901 heat shock protein 82\tK04079 HSP90A; molecular chaperone HtpG"
			},
			{
				"name":"UREG_02880 enolase 2\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"UREG_07866 phosphopyruvate hydratase\tK01689 ENO1_2_3; enolase 1\/2\/3 [EC:4.2.1.11]"
			},
			{
				"name":"UREG_04000 glyceraldehyde-3-phosphate dehydrogenase, type I\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
			},
			{
				"name":"UREG_03420 phosphoglycerate kinase\tK00927 PGK; phosphoglycerate kinase [EC:2.7.2.3]"
			},
			{
				"name":"UREG_02318 pyruvate kinase\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
			},
			{
				"name":"UREG_03382 hypothetical protein\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"UREG_05177 hypothetical protein\tK01273 DPEP; membrane dipeptidase [EC:3.4.13.19]"
			},
			{
				"name":"UREG_05606 pH-response regulator protein palA\/RIM20\tK12200 PDCD6IP; programmed cell death 6-interacting protein"
			},
			{
				"name":"UREG_00232 hypothetical protein\tK12183 TSG101; ESCRT-I complex subunit TSG101"
			},
			{
				"name":"UREG_03656 guanine nucleotide-binding protein alpha subunit\tK04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha"
			},
			{
				"name":"UREG_04434 guanine nucleotide-binding protein alpha-3 subunit\tK04630 GNAI; guanine nucleotide-binding protein G(i) subunit alpha"
			},
			{
				"name":"UREG_01748 DNA damage checkpoint protein rad24\tK06630 YWHAE; 14-3-3 protein epsilon"
			},
			{
				"name":"UREG_07864 14-3-3 protein epsilon\tK06630 YWHAE; 14-3-3 protein epsilon"
			},
			{
				"name":"UREG_07557 translation elongation factor EF-1, subunit alpha\tK03231 EEF1A; elongation factor 1-alpha"
			},
			{
				"name":"UREG_06526 elongation factor 2\tK03234 EEF2; elongation factor 2"
			},
			{
				"name":"UREG_05863 ADP-ribosylation factor\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
			},
			{
				"name":"UREG_04750 clathrin heavy chain\tK04646 CLTC; clathrin heavy chain"
			},
			{
				"name":"UREG_02265 rab GDP dissociation inhibitor alpha\tK17255 GDI1_2; Rab GDP dissociation inhibitor"
			},
			{
				"name":"UREG_00839 hypothetical protein\tK07192 FLOT; flotillin"
			}
			]
		},
		{
			"name":"Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)",
			"children":[
			{
				"name":"UREG_04451 actin\tK17260 ACTR2; actin-related protein 2"
			},
			{
				"name":"UREG_05207 actin\tK18584 ACTR3; actin-related protein 3"
			},
			{
				"name":"UREG_03636 hypothetical protein\tK17261 CAP1_2; adenylyl cyclase-associated protein"
			},
			{
				"name":"UREG_06748 F-actin capping protein beta subunit isoforms 1 and 2\tK10365 CAPZB; F-actin-capping protein subunit beta"
			},
			{
				"name":"UREG_01444 DNM1 protein\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
			},
			{
				"name":"UREG_02972 kinesin heavy chain\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
			},
			{
				"name":"UREG_04554 prohibitin\tK17080 PHB1; prohibitin 1"
			},
			{
				"name":"UREG_06390 cell division control protein 3\tK16944 SEPT7; septin 7"
			},
			{
				"name":"UREG_05710 similar to septin 3 isoform B variant\tK16938 SEPT3_9_12; septin 3\/9\/12"
			},
			{
				"name":"UREG_03458 hypothetical protein\tK16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha"
			},
			{
				"name":"UREG_01340 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_04085 tubulin alpha chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_03196 hypothetical protein\tK17262 TBCB; tubulin-specific chaperone B"
			},
			{
				"name":"UREG_02437 hypothetical protein\tK16569 TUBGCP2; gamma-tubulin complex component 2"
			},
			{
				"name":"UREG_07458 hypothetical protein\tK16570 TUBGCP3; gamma-tubulin complex component 3"
			},
			{
				"name":"UREG_01160 heat shock protein 70\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
			},
			{
				"name":"UREG_04105 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"UREG_01663 chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"UREG_00388 T-complex protein 1, alpha subunit\tK09493 CCT1; T-complex protein 1 subunit alpha"
			},
			{
				"name":"UREG_06055 T-complex protein 1 subunit beta\tK09494 CCT2; T-complex protein 1 subunit beta"
			},
			{
				"name":"UREG_07268 T-complex protein 1, gamma subunit\tK09495 CCT3; T-complex protein 1 subunit gamma"
			},
			{
				"name":"UREG_01413 T-complex protein 1, delta subunit\tK09496 CCT4; T-complex protein 1 subunit delta"
			},
			{
				"name":"UREG_01216 T-complex protein 1, epsilon subunit\tK09497 CCT5; T-complex protein 1 subunit epsilon"
			},
			{
				"name":"UREG_06846 T-complex protein 1, zeta subunit\tK09498 CCT6; T-complex protein 1 subunit zeta"
			},
			{
				"name":"UREG_01955 T-complex protein 1, eta subunit\tK09499 CCT7; T-complex protein 1 subunit eta"
			},
			{
				"name":"UREG_04629 ATP-citrate synthase subunit 1\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_04630 similar to ATP-citrat-lyase\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_02168 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"UREG_01031 similar to aspartate aminotransferase\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
			},
			{
				"name":"UREG_02186 aspartate aminotransferase\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
			},
			{
				"name":"UREG_04602 serine\/threonine-protein phosphatase PP2A catalytic subunit\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
			},
			{
				"name":"UREG_00539 DNA-repair protein rad2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
			},
			{
				"name":"UREG_01716 inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"UREG_07465 ubiquitin\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			},
			{
				"name":"UREG_04931 hypothetical protein\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
			},
			{
				"name":"UREG_02896 hypothetical protein\tK12184 VPS28; ESCRT-I complex subunit VPS28"
			},
			{
				"name":"UREG_02531 hypothetical protein\tK12197 CHMP1; charged multivesicular body protein 1"
			},
			{
				"name":"UREG_04941 charged multivesicular body protein 2a\tK12191 CHMP2A; charged multivesicular body protein 2A"
			},
			{
				"name":"UREG_01984 vacuolar sorting protein snf-7\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
			},
			{
				"name":"UREG_05757 hypothetical protein\tK12195 CHMP6; charged multivesicular body protein 6"
			},
			{
				"name":"UREG_00365 ubiquitin-activating enzyme E1 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			},
			{
				"name":"UREG_05674 hypothetical protein\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
			},
			{
				"name":"UREG_03050 proteasome component PRE5\tK02725 PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
			},
			{
				"name":"UREG_03372 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"UREG_07452 hypothetical protein\tK03250 EIF3E; translation initiation factor 3 subunit E"
			},
			{
				"name":"UREG_05766 hypothetical protein\tK03249 EIF3F; translation initiation factor 3 subunit F"
			},
			{
				"name":"UREG_07691 eukaryotic initiation factor 4A-6\tK03257 EIF4A; translation initiation factor 4A"
			},
			{
				"name":"UREG_06340 hypothetical protein\tK17095 ANXA7_11; annexin A7\/11"
			},
			{
				"name":"UREG_03834 Na\/K ATPase alpha 1 isoform\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"UREG_05045 guanine nucleotide-binding protein beta subunit\tK04536 GNB1; guanine nucleotide-binding protein G(I)\/G(S)\/G(T) subunit beta-1"
			},
			{
				"name":"UREG_03487 GTP-binding nuclear protein GSP1\/Ran\tK07936 RAN; GTP-binding nuclear protein Ran"
			},
			{
				"name":"UREG_02758 GTP-binding protein ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
			},
			{
				"name":"UREG_05058 GTP-binding protein ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
			},
			{
				"name":"UREG_02573 GTP-binding protein SAS1\tK07901 RAB8A; Ras-related protein Rab-8A"
			},
			{
				"name":"UREG_00468 cell division control protein 42\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
			},
			{
				"name":"UREG_03736 krev-1 protein\tK07836 RAP1B; Ras-related protein Rap-1B"
			},
			{
				"name":"UREG_01930 protein rho5\tK04513 RHOA; Ras homolog gene family, member A"
			},
			{
				"name":"UREG_00170 ADP-ribosylation factor 6\tK07941 ARF6; ADP-ribosylation factor 6"
			},
			{
				"name":"UREG_05192 similar to GDP dissociation inhibitor\tK12462 ARHGDI; Rho GDP-dissociation inhibitor"
			},
			{
				"name":"UREG_05505 similar to coatomer protein complex\tK17267 COPG; coatomer subunit gamma"
			},
			{
				"name":"UREG_05430 mitogen-activated protein kinase\tK04371 ERK; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]"
			},
			{
				"name":"UREG_02077 hypothetical protein\tK10089 M6PR; cation-dependent mannose-6-phosphate receptor"
			},
			{
				"name":"UREG_02982 hypothetical protein\tK17086 TM9SF2_4; transmembrane 9 superfamily member 2\/4"
			},
			{
				"name":"UREG_03500 hypothetical protein\tK17086 TM9SF2_4; transmembrane 9 superfamily member 2\/4"
			},
			{
				"name":"UREG_04612 nuclear migration protein nudF\tK16794 PAFAH1B1; platelet-activating factor acetylhydrolase IB subunit alpha"
			},
			{
				"name":"UREG_07677 nuclear migration protein nudF\tK16794 PAFAH1B1; platelet-activating factor acetylhydrolase IB subunit alpha"
			},
			{
				"name":"UREG_04902 cell division cycle protein 48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
			},
			{
				"name":"UREG_04002 histone H2A variant\tK11251 H2A; histone H2A"
			},
			{
				"name":"UREG_06993 histone H2A\tK11251 H2A; histone H2A"
			},
			{
				"name":"UREG_06992 histone H2B\tK11252 H2B; histone H2B"
			},
			{
				"name":"UREG_07214 histone H3.3\tK11253 H3; histone H3"
			}
			]
		},
		{
			"name":"Exosomal proteins of oligodendrocytes"
		},
		{
			"name":"Exosomal proteins of cortical neuronal cells"
		},
		{
			"name":"Exosomal proteins of microglial cells",
			"children":[
			{
				"name":"UREG_00754 cell division control protein 42\tK04393 CDC42; cell division control protein 42"
			},
			{
				"name":"UREG_05766 hypothetical protein\tK03249 EIF3F; translation initiation factor 3 subunit F"
			},
			{
				"name":"UREG_00917 fimbrin\tK17275 PLS1; plastin-1"
			}
			]
		},
		{
			"name":"Exosomal proteins of epithelial cells",
			"children":[
			{
				"name":"UREG_02364 hypothetical protein\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
			}
			]
		},
		{
			"name":"Exosomal proteins of hepatic cells",
			"children":[
			{
				"name":"UREG_07384 damage response protein 1\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
			},
			{
				"name":"UREG_04379 protein yop-1\tK17279 REEP5_6; receptor expression-enhancing protein 5\/6"
			},
			{
				"name":"UREG_04887 hypothetical protein\tK14347 SLC10A7; solute carrier family 10 (sodium\/bile acid cotransporter), member 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast milk",
			"children":[
			{
				"name":"UREG_01671 hypothetical protein\tK05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2"
			},
			{
				"name":"UREG_02290 hypothetical protein\tK05681 ABCG2; ATP-binding cassette, subfamily G (WHITE), member 2"
			},
			{
				"name":"UREG_02149 hypothetical protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"UREG_04081 hypothetical protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"UREG_00754 cell division control protein 42\tK04393 CDC42; cell division control protein 42"
			},
			{
				"name":"UREG_07319 hypothetical protein\tK17286 STOM; stomatin"
			},
			{
				"name":"UREG_00590 ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"UREG_05104 xanthine dehydrogenase\tK00106 XDH; xanthine dehydrogenase\/oxidase [EC:1.17.1.4 1.17.3.2]"
			}
			]
		},
		{
			"name":"Exosomal proteins of other body fluids (saliva and urine)",
			"children":[
			{
				"name":"UREG_04451 actin\tK17260 ACTR2; actin-related protein 2"
			},
			{
				"name":"UREG_05207 actin\tK18584 ACTR3; actin-related protein 3"
			},
			{
				"name":"UREG_01340 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_04085 tubulin alpha chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_05920 tubulin beta chain\tK07375 TUBB; tubulin beta"
			},
			{
				"name":"UREG_01160 heat shock protein 70\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
			},
			{
				"name":"UREG_04105 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"UREG_01473 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"UREG_02971 acetyl-CoA acetyltransferase\tK00626 ACAT; acetyl-CoA C-acetyltransferase [EC:2.3.1.9]"
			},
			{
				"name":"UREG_03427 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
			},
			{
				"name":"UREG_03201 adenylate kinase cytosolic\tK00939 adk; adenylate kinase [EC:2.7.4.3]"
			},
			{
				"name":"UREG_02100 adenine phosphoribosyltransferase 1\tK00759 APRT; adenine phosphoribosyltransferase [EC:2.4.2.7]"
			},
			{
				"name":"UREG_01298 argininosuccinate lyase\tK01755 argH; argininosuccinate lyase [EC:4.3.2.1]"
			},
			{
				"name":"UREG_05285 vacuolar ATP synthase 98 kDa subunit\tK02154 ATPeV0A; V-type H+-transporting ATPase subunit a"
			},
			{
				"name":"UREG_06480 V-type ATPase, B subunit\tK02147 ATPeV1B; V-type H+-transporting ATPase subunit B"
			},
			{
				"name":"UREG_03834 Na\/K ATPase alpha 1 isoform\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"UREG_03020 carboxypeptidase Y\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
			},
			{
				"name":"UREG_06044 carboxypeptidase Y\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
			},
			{
				"name":"UREG_01504 cystathionine gamma-lyase\tK01758 CTH; cystathionine gamma-lyase [EC:4.4.1.1]"
			},
			{
				"name":"UREG_02527 hypothetical protein\tK01593 DDC; aromatic-L-amino-acid\/L-tryptophan decarboxylase [EC:4.1.1.28 4.1.1.105]"
			},
			{
				"name":"UREG_01239 fumarylacetoacetase\tK01555 FAH; fumarylacetoacetase [EC:3.7.1.2]"
			},
			{
				"name":"UREG_05283 fructose-1,6-bisphosphatase\tK03841 FBP; fructose-1,6-bisphosphatase I [EC:3.1.3.11]"
			},
			{
				"name":"UREG_07362 galactokinase\tK00849 galK; galactokinase [EC:2.7.1.6]"
			},
			{
				"name":"UREG_04110 1,4-alpha-glucan branching enzyme\tK00700 GBE1; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]"
			},
			{
				"name":"UREG_03540 similar to glucosidase I\tK01228 MOGS; mannosyl-oligosaccharide glucosidase [EC:3.2.1.106]"
			},
			{
				"name":"UREG_03589 glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"UREG_05304 glycerol kinase\tK00864 glpK; glycerol kinase [EC:2.7.1.30]"
			},
			{
				"name":"UREG_05173 glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"UREG_05961 similar to glutamine synthetase\tK01915 glnA; glutamine synthetase [EC:6.3.1.2]"
			},
			{
				"name":"UREG_02168 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"UREG_01031 similar to aspartate aminotransferase\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
			},
			{
				"name":"UREG_02186 aspartate aminotransferase\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
			},
			{
				"name":"UREG_04364 hypothetical protein\tK21456 GSS; glutathione synthase [EC:6.3.2.3]"
			},
			{
				"name":"UREG_05690 delta-aminolevulinic acid dehydratase\tK01698 hemB; porphobilinogen synthase [EC:4.2.1.24]"
			},
			{
				"name":"UREG_01236 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"UREG_05130 4-hydroxyphenylpyruvate dioxygenase\tK00457 HPD; 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27]"
			},
			{
				"name":"UREG_06285 hypothetical protein\tK00846 KHK; ketohexokinase [EC:2.7.1.3]"
			},
			{
				"name":"UREG_02609 succinyl-CoA ligase beta-chain\tK01900 LSC2; succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5]"
			},
			{
				"name":"UREG_07615 C-1-tetrahydrofolate synthase\tK00288 MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) \/ methenyltetrahydrofolate cyclohydrolase \/ formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]"
			},
			{
				"name":"UREG_02576 hypothetical protein\tK01724 PCBD; 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96]"
			},
			{
				"name":"UREG_01769 repressible alkaline phosphatase\tK01077 ALP; alkaline phosphatase [EC:3.1.3.1]"
			},
			{
				"name":"UREG_01171 hypothetical protein\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"UREG_04045 D-3-phosphoglycerate dehydrogenase 1\tK00058 serA; D-3-phosphoglycerate dehydrogenase \/ 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]"
			},
			{
				"name":"UREG_04751 phosphoribosylaminoimidazolecarboxamide formyltransferase\/IMP cyclohydrolase\tK00602 purH; phosphoribosylaminoimidazolecarboxamide formyltransferase \/ IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]"
			},
			{
				"name":"UREG_04768 similar to CaaX prenyl protease\tK06013 STE24; STE24 endopeptidase [EC:3.4.24.84]"
			},
			{
				"name":"UREG_00260 similar to tripeptidyl peptidase A\tK01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]"
			},
			{
				"name":"UREG_01816 hypothetical protein\tK01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]"
			},
			{
				"name":"UREG_02074 similar to fuSed3 protease\tK01279 TPP1; tripeptidyl-peptidase I [EC:3.4.14.9]"
			},
			{
				"name":"UREG_02896 hypothetical protein\tK12184 VPS28; ESCRT-I complex subunit VPS28"
			},
			{
				"name":"UREG_02205 hypothetical protein\tK12188 SNF8; ESCRT-II complex subunit VPS22"
			},
			{
				"name":"UREG_05808 hypothetical protein\tK12189 VPS25; ESCRT-II complex subunit VPS25"
			},
			{
				"name":"UREG_02651 hypothetical protein\tK12190 VPS36; ESCRT-II complex subunit VPS36"
			},
			{
				"name":"UREG_02531 hypothetical protein\tK12197 CHMP1; charged multivesicular body protein 1"
			},
			{
				"name":"UREG_04941 charged multivesicular body protein 2a\tK12191 CHMP2A; charged multivesicular body protein 2A"
			},
			{
				"name":"UREG_04704 hypothetical protein\tK12193 VPS24; charged multivesicular body protein 3"
			},
			{
				"name":"UREG_01984 vacuolar sorting protein snf-7\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
			},
			{
				"name":"UREG_05757 hypothetical protein\tK12195 CHMP6; charged multivesicular body protein 6"
			},
			{
				"name":"UREG_04858 hypothetical protein\tK15053 CHMP7; charged multivesicular body protein 7"
			},
			{
				"name":"UREG_00590 ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"UREG_00365 ubiquitin-activating enzyme E1 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			},
			{
				"name":"UREG_05192 similar to GDP dissociation inhibitor\tK12462 ARHGDI; Rho GDP-dissociation inhibitor"
			},
			{
				"name":"UREG_02137 hypothetical protein\tK00002 AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
			},
			{
				"name":"UREG_03469 similar to aldehyde reductase\tK00002 AKR1A1; alcohol dehydrogenase (NADP+) [EC:1.1.1.2]"
			},
			{
				"name":"UREG_01909 hypothetical protein\tK00522 FTH1; ferritin heavy chain [EC:1.16.3.1]"
			},
			{
				"name":"UREG_06340 hypothetical protein\tK17095 ANXA7_11; annexin A7\/11"
			},
			{
				"name":"UREG_01930 protein rho5\tK04513 RHOA; Ras homolog gene family, member A"
			},
			{
				"name":"UREG_03736 krev-1 protein\tK07836 RAP1B; Ras-related protein Rap-1B"
			},
			{
				"name":"UREG_02758 GTP-binding protein ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
			},
			{
				"name":"UREG_05058 GTP-binding protein ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
			},
			{
				"name":"UREG_02573 GTP-binding protein SAS1\tK07901 RAB8A; Ras-related protein Rab-8A"
			},
			{
				"name":"UREG_04118 GTP-binding protein ypt3\tK07904 RAB11A; Ras-related protein Rab-11A"
			},
			{
				"name":"UREG_00468 cell division control protein 42\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
			},
			{
				"name":"UREG_05165 similar to receptor of activated protein kinase C 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
			},
			{
				"name":"UREG_01715 hypothetical protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
			},
			{
				"name":"UREG_06880 ras-GAP protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
			},
			{
				"name":"UREG_00162 multidrug resistance protein 1\tK05658 ABCB1; ATP-binding cassette, subfamily B (MDR\/TAP), member 1 [EC:7.6.2.2]"
			},
			{
				"name":"UREG_00750 similar to P-glycoprotein\tK05658 ABCB1; ATP-binding cassette, subfamily B (MDR\/TAP), member 1 [EC:7.6.2.2]"
			},
			{
				"name":"UREG_01347 similar to ABC transporter\tK05658 ABCB1; ATP-binding cassette, subfamily B (MDR\/TAP), member 1 [EC:7.6.2.2]"
			},
			{
				"name":"UREG_02492 hypothetical protein\tK05658 ABCB1; ATP-binding cassette, subfamily B (MDR\/TAP), member 1 [EC:7.6.2.2]"
			},
			{
				"name":"UREG_04188 multidrug resistance protein 3\tK05658 ABCB1; ATP-binding cassette, subfamily B (MDR\/TAP), member 1 [EC:7.6.2.2]"
			},
			{
				"name":"UREG_07591 coatomer alpha subunit\tK05236 COPA; coatomer subunit alpha"
			},
			{
				"name":"UREG_06719 hypothetical protein\tK12386 CTNS; cystinosin"
			},
			{
				"name":"UREG_05000 hypothetical protein\tK10609 CUL4; cullin 4"
			},
			{
				"name":"UREG_07061 similar to inorganic phosphate transporter\tK15102 SLC25A3; solute carrier family 25 (mitochondrial phosphate transporter), member 3"
			},
			{
				"name":"UREG_07620 mitochondrial phosphate carrier protein 2\tK15102 SLC25A3; solute carrier family 25 (mitochondrial phosphate transporter), member 3"
			},
			{
				"name":"UREG_02364 hypothetical protein\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
			},
			{
				"name":"UREG_00717 hypothetical protein\tK15292 STXBP1; syntaxin-binding protein 1"
			},
			{
				"name":"UREG_04711 hypothetical protein\tK08515 VAMP7; vesicle-associated membrane protein 7"
			}
			]
		},
		{
			"name":"Exosomal proteins of breast cancer cells",
			"children":[
			{
				"name":"UREG_02149 hypothetical protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"UREG_04081 hypothetical protein\tK01897 ACSL; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"UREG_06178 dihydrolipoyl dehydrogenase\tK00382 DLD; dihydrolipoyl dehydrogenase [EC:1.8.1.4]"
			},
			{
				"name":"UREG_06368 electron transfer flavoprotein alpha-subunit\tK03522 fixB; electron transfer flavoprotein alpha subunit"
			},
			{
				"name":"UREG_07624 glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"UREG_01716 inosine-5'-monophosphate dehydrogenase\tK00088 IMPDH; IMP dehydrogenase [EC:1.1.1.205]"
			},
			{
				"name":"UREG_04554 prohibitin\tK17080 PHB1; prohibitin 1"
			},
			{
				"name":"UREG_05680 protein disulfide-isomerase\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"UREG_01663 chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"UREG_04105 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"UREG_03372 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
			}
			]
		},
		{
			"name":"Exosomal proteins of ovarian cancer cells"
		},
		{
			"name":"Exosomal proteins of colorectal cancer cells",
			"children":[
			{
				"name":"UREG_02636 similar to alpha-adaptin C\tK11824 AP2A; AP-2 complex subunit alpha"
			},
			{
				"name":"UREG_01340 tubulin alpha-1 chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_04085 tubulin alpha chain\tK07374 TUBA; tubulin alpha"
			},
			{
				"name":"UREG_05920 tubulin beta chain\tK07375 TUBB; tubulin beta"
			},
			{
				"name":"UREG_01160 heat shock protein 70\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
			},
			{
				"name":"UREG_04105 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"UREG_00388 T-complex protein 1, alpha subunit\tK09493 CCT1; T-complex protein 1 subunit alpha"
			},
			{
				"name":"UREG_06055 T-complex protein 1 subunit beta\tK09494 CCT2; T-complex protein 1 subunit beta"
			},
			{
				"name":"UREG_07268 T-complex protein 1, gamma subunit\tK09495 CCT3; T-complex protein 1 subunit gamma"
			},
			{
				"name":"UREG_01413 T-complex protein 1, delta subunit\tK09496 CCT4; T-complex protein 1 subunit delta"
			},
			{
				"name":"UREG_01216 T-complex protein 1, epsilon subunit\tK09497 CCT5; T-complex protein 1 subunit epsilon"
			},
			{
				"name":"UREG_06846 T-complex protein 1, zeta subunit\tK09498 CCT6; T-complex protein 1 subunit zeta"
			},
			{
				"name":"UREG_01955 T-complex protein 1, eta subunit\tK09499 CCT7; T-complex protein 1 subunit eta"
			},
			{
				"name":"UREG_02168 glucose-6-phosphate isomerase\tK01810 GPI; glucose-6-phosphate isomerase [EC:5.3.1.9]"
			},
			{
				"name":"UREG_04554 prohibitin\tK17080 PHB1; prohibitin 1"
			},
			{
				"name":"UREG_00967 prohibitin-2\tK17081 PHB2; prohibitin 2"
			},
			{
				"name":"UREG_00837 hypothetical protein\tK17292 TBCA; tubulin-specific chaperone A"
			},
			{
				"name":"UREG_07624 glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"UREG_05680 protein disulfide-isomerase\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"UREG_01663 chaperone DnaK\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"UREG_03296 calmodulin\tK02183 CALM; calmodulin"
			},
			{
				"name":"UREG_02232 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"UREG_04952 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"UREG_02896 hypothetical protein\tK12184 VPS28; ESCRT-I complex subunit VPS28"
			},
			{
				"name":"UREG_05808 hypothetical protein\tK12189 VPS25; ESCRT-II complex subunit VPS25"
			},
			{
				"name":"UREG_02651 hypothetical protein\tK12190 VPS36; ESCRT-II complex subunit VPS36"
			},
			{
				"name":"UREG_02531 hypothetical protein\tK12197 CHMP1; charged multivesicular body protein 1"
			},
			{
				"name":"UREG_04941 charged multivesicular body protein 2a\tK12191 CHMP2A; charged multivesicular body protein 2A"
			},
			{
				"name":"UREG_01984 vacuolar sorting protein snf-7\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
			},
			{
				"name":"UREG_00590 ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"UREG_00365 ubiquitin-activating enzyme E1 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			},
			{
				"name":"UREG_07465 ubiquitin\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			},
			{
				"name":"UREG_03445 hypothetical protein\tK03247 EIF3H; translation initiation factor 3 subunit H"
			},
			{
				"name":"UREG_03372 translation elongation factor Tu\tK02358 tuf; elongation factor Tu"
			},
			{
				"name":"UREG_06340 hypothetical protein\tK17095 ANXA7_11; annexin A7\/11"
			},
			{
				"name":"UREG_00170 ADP-ribosylation factor 6\tK07941 ARF6; ADP-ribosylation factor 6"
			},
			{
				"name":"UREG_03834 Na\/K ATPase alpha 1 isoform\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"UREG_05914 coatomer beta subunit\tK17301 COPB1; coatomer subunit beta"
			},
			{
				"name":"UREG_02221 coatomer beta' subunit\tK17302 COPB2; coatomer subunit beta'"
			},
			{
				"name":"UREG_01930 protein rho5\tK04513 RHOA; Ras homolog gene family, member A"
			},
			{
				"name":"UREG_05192 similar to GDP dissociation inhibitor\tK12462 ARHGDI; Rho GDP-dissociation inhibitor"
			},
			{
				"name":"UREG_03736 krev-1 protein\tK07836 RAP1B; Ras-related protein Rap-1B"
			},
			{
				"name":"UREG_07582 GTP-binding protein ypt4\tK07880 RAB4B; Ras-related protein Rab-4B"
			},
			{
				"name":"UREG_02758 GTP-binding protein ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
			},
			{
				"name":"UREG_05058 GTP-binding protein ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
			},
			{
				"name":"UREG_02573 GTP-binding protein SAS1\tK07901 RAB8A; Ras-related protein Rab-8A"
			},
			{
				"name":"UREG_04118 GTP-binding protein ypt3\tK07904 RAB11A; Ras-related protein Rab-11A"
			},
			{
				"name":"UREG_00468 cell division control protein 42\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
			},
			{
				"name":"UREG_05165 similar to receptor of activated protein kinase C 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
			},
			{
				"name":"UREG_01715 hypothetical protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
			},
			{
				"name":"UREG_06880 ras-GAP protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
			},
			{
				"name":"UREG_05045 guanine nucleotide-binding protein beta subunit\tK04536 GNB1; guanine nucleotide-binding protein G(I)\/G(S)\/G(T) subunit beta-1"
			}
			]
		},
		{
			"name":"Exosomal proteins of pancreatic cancer cells"
		},
		{
			"name":"Exosomal proteins of bladder cancer cells",
			"children":[
			{
				"name":"UREG_00576 actin-1\tK16575 ACTR1; centractin"
			},
			{
				"name":"UREG_04451 actin\tK17260 ACTR2; actin-related protein 2"
			},
			{
				"name":"UREG_05207 actin\tK18584 ACTR3; actin-related protein 3"
			},
			{
				"name":"UREG_03702 myosin-11 (Myosin heavy chain\tK10352 MYH9s; myosin heavy chain 9\/10\/11\/14"
			},
			{
				"name":"UREG_05920 tubulin beta chain\tK07375 TUBB; tubulin beta"
			},
			{
				"name":"UREG_04105 chaperonin GroL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			},
			{
				"name":"UREG_00388 T-complex protein 1, alpha subunit\tK09493 CCT1; T-complex protein 1 subunit alpha"
			},
			{
				"name":"UREG_06055 T-complex protein 1 subunit beta\tK09494 CCT2; T-complex protein 1 subunit beta"
			},
			{
				"name":"UREG_07268 T-complex protein 1, gamma subunit\tK09495 CCT3; T-complex protein 1 subunit gamma"
			},
			{
				"name":"UREG_01413 T-complex protein 1, delta subunit\tK09496 CCT4; T-complex protein 1 subunit delta"
			},
			{
				"name":"UREG_01216 T-complex protein 1, epsilon subunit\tK09497 CCT5; T-complex protein 1 subunit epsilon"
			},
			{
				"name":"UREG_06846 T-complex protein 1, zeta subunit\tK09498 CCT6; T-complex protein 1 subunit zeta"
			},
			{
				"name":"UREG_01955 T-complex protein 1, eta subunit\tK09499 CCT7; T-complex protein 1 subunit eta"
			},
			{
				"name":"UREG_04629 ATP-citrate synthase subunit 1\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_04630 similar to ATP-citrat-lyase\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_01909 hypothetical protein\tK00522 FTH1; ferritin heavy chain [EC:1.16.3.1]"
			},
			{
				"name":"UREG_07624 glucose-6-phosphate dehydrogenase\tK00036 G6PD; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]"
			},
			{
				"name":"UREG_05680 protein disulfide-isomerase\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
			},
			{
				"name":"UREG_02896 hypothetical protein\tK12184 VPS28; ESCRT-I complex subunit VPS28"
			},
			{
				"name":"UREG_00590 ubiquitin\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"UREG_07691 eukaryotic initiation factor 4A-6\tK03257 EIF4A; translation initiation factor 4A"
			},
			{
				"name":"UREG_06340 hypothetical protein\tK17095 ANXA7_11; annexin A7\/11"
			},
			{
				"name":"UREG_03834 Na\/K ATPase alpha 1 isoform\tK01539 ATP1A; sodium\/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]"
			},
			{
				"name":"UREG_07591 coatomer alpha subunit\tK05236 COPA; coatomer subunit alpha"
			},
			{
				"name":"UREG_01930 protein rho5\tK04513 RHOA; Ras homolog gene family, member A"
			},
			{
				"name":"UREG_05058 GTP-binding protein ypt7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
			},
			{
				"name":"UREG_00468 cell division control protein 42\tK04392 RAC1; Ras-related C3 botulinum toxin substrate 1"
			},
			{
				"name":"UREG_05165 similar to receptor of activated protein kinase C 1\tK14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein"
			},
			{
				"name":"UREG_02232 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"UREG_04952 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			}
			]
		},
		{
			"name":"Exosomal proteins of melanoma cells",
			"children":[
			{
				"name":"UREG_04629 ATP-citrate synthase subunit 1\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_04630 similar to ATP-citrat-lyase\tK01648 ACLY; ATP citrate (pro-S)-lyase [EC:2.3.3.8]"
			},
			{
				"name":"UREG_02232 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"UREG_04952 triosephosphate isomerase\tK01803 TPI; triosephosphate isomerase (TIM) [EC:5.3.1.1]"
			},
			{
				"name":"UREG_02758 GTP-binding protein ypt5\tK07888 RAB5B; Ras-related protein Rab-5B"
			},
			{
				"name":"UREG_05045 guanine nucleotide-binding protein beta subunit\tK04536 GNB1; guanine nucleotide-binding protein G(I)\/G(S)\/G(T) subunit beta-1"
			}
			]
		},
		{
			"name":"Exosomal proteins of other cancer cells"
		}
		]
	},
	{
		"name":"Exosomal RNA",
		"children":[
		{
			"name":"Exosomal RNA of haemopoietic cells"
		},
		{
			"name":"Exosomal RNA of muscle cells"
		},
		{
			"name":"Exosomal RNA of hepatic cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cells"
		},
		{
			"name":"Exosomal RNA of neural cells"
		},
		{
			"name":"Exosomal RNA of breast milk"
		},
		{
			"name":"Exosomal RNA of saliva"
		},
		{
			"name":"Exosomal RNA of breast cancer cells"
		},
		{
			"name":"Exosomal RNA of ovarian cancer cells"
		},
		{
			"name":"Exosomal RNA of colorectal cancer cells"
		},
		{
			"name":"Exosomal RNA of hepatic cancer cells"
		},
		{
			"name":"Exosomal RNA of renal carcinoma cells"
		},
		{
			"name":"Exosomal RNA of pancreatic cancer cells"
		},
		{
			"name":"Exosomal RNA of melanoma cells"
		},
		{
			"name":"Exosomal RNA of lung cancer cells"
		},
		{
			"name":"Exosomal RNA of other cancer cells"
		}
		]
	}
	]
}
