{
	"name":"vaa03000",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Basic leucine zipper (bZIP)",
			"children":[
			{
				"name":"AP-1(-like) components, Jun"
			},
			{
				"name":"AP-1(-like) components, Fos"
			},
			{
				"name":"AP-1(-like) components, Maf"
			},
			{
				"name":"AP-1(-like) components, NF-E2"
			},
			{
				"name":"AP-1(-like) components, Fungal regulators"
			},
			{
				"name":"AP-1(-like) components, CRE-BP\/ATF"
			},
			{
				"name":"CREB"
			},
			{
				"name":"C\/EBP-like factors"
			},
			{
				"name":"bZIP\/PAR"
			},
			{
				"name":"Plant bZIP factors"
			},
			{
				"name":"ZIP only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix (bHLH)",
			"children":[
			{
				"name":"Ubiquitous (class A) factors"
			},
			{
				"name":"Myogenic transcription factors"
			},
			{
				"name":"Achaete-Scute"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Lymphoid factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesodermal Twist-like factors"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, HEN"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Mesp"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Atonal"
			},
			{
				"name":"Tal\/Twist\/Atonal\/Hen, Pancreatic factors"
			},
			{
				"name":"Hairy, Hairy\/E(SPL)"
			},
			{
				"name":"Hairy, Fungal regulators"
			},
			{
				"name":"Factors with PAS domain"
			},
			{
				"name":"Yabby"
			},
			{
				"name":"INO"
			},
			{
				"name":"HLH domain only"
			}
			]
		},
		{
			"name":"Basic helix-loop-helix\/leucine zipper (bHLH-ZIP)",
			"children":[
			{
				"name":"Ubiquitous bHLH-ZIP factors"
			},
			{
				"name":"Cell cycle controlling factors, Myc"
			},
			{
				"name":"Cell cycle controlling factors, Mad\/Max"
			},
			{
				"name":"Other bHLH-ZIP factors"
			}
			]
		},
		{
			"name":"Other basic domains",
			"children":[
			{
				"name":"NF-1"
			},
			{
				"name":"RF-X"
			},
			{
				"name":"AP-2 (bHSH)"
			}
			]
		},
		{
			"name":"Zinc finger",
			"children":[
			{
				"name":"Cys4 thyroid hormone receptor-like"
			},
			{
				"name":"Cys4 hepatocyte nuclear factor 4-like"
			},
			{
				"name":"Cys4 estrogen receptor-like"
			},
			{
				"name":"Cys4 nerve growth factor IB-like"
			},
			{
				"name":"Cys4 Fushi tarazu-F1-like"
			},
			{
				"name":"Cys4 germ cell nuclear factor"
			},
			{
				"name":"Cys4 Knirps\/DAX1-like"
			},
			{
				"name":"Cys4 GATA-factors"
			},
			{
				"name":"Cys2His2 SP\/KLF family and related proteins"
			},
			{
				"name":"Cys2His2 GLI-like"
			},
			{
				"name":"Cys2His2 Snail"
			},
			{
				"name":"Cys2His2 BTB-ZF factors"
			},
			{
				"name":"Cys2His2 BED"
			},
			{
				"name":"Cys2His2 PRDM"
			},
			{
				"name":"Cys2His2 metabolic regulators in fungi"
			},
			{
				"name":"Cys2His2 others"
			},
			{
				"name":"Cys2HisCys zinc factors"
			},
			{
				"name":"Cys3His zinc factors"
			},
			{
				"name":"Cys2CysHis zinc factors"
			},
			{
				"name":"CXXC CpG-binding proteins"
			},
			{
				"name":"Cys6 metabolic regulators in fungi"
			},
			{
				"name":"Other zinc fingers"
			}
			]
		},
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"Homeo domain ANTP: HOXL"
			},
			{
				"name":"Homeo domain ANTP: NKL"
			},
			{
				"name":"Homeo domain Paired-related"
			},
			{
				"name":"Homeo domain LIM"
			},
			{
				"name":"Homeo domain POU"
			},
			{
				"name":"Homeo domain SINE"
			},
			{
				"name":"Homeo domain ZF"
			},
			{
				"name":"Homeo domain CUT"
			},
			{
				"name":"Homeo domain PROS"
			},
			{
				"name":"Homeo domain TALE"
			},
			{
				"name":"Homeo domain other"
			},
			{
				"name":"Fork head\/winged helix developmental regulators"
			},
			{
				"name":"Fork head\/winged helix tissue-specific regulators"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, E2F"
			},
			{
				"name":"Fork head\/winged helix cell cycle-controlling factors, DP"
			},
			{
				"name":"Fork head\/winged helix other regulators"
			},
			{
				"name":"Stork head\/winged helix factors"
			},
			{
				"name":"Heat shock factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-factors"
			},
			{
				"name":"Tryptophan clusters Myb, Myb-like factors"
			},
			{
				"name":"Tryptophan clusters Ets-type"
			},
			{
				"name":"Tryptophan clusters interferon-regulating factors"
			},
			{
				"name":"TEA domain"
			},
			{
				"name":"ARID"
			}
			]
		},
		{
			"name":"beta-Scaffold factors with minor groove contacts",
			"children":[
			{
				"name":"RHR (Rel homology region) Rel\/Ankyrin"
			},
			{
				"name":"RHR (Rel homology region) Ankyrin only"
			},
			{
				"name":"RHR (Rel homology region) NF-AT"
			},
			{
				"name":"STAT"
			},
			{
				"name":"p53"
			},
			{
				"name":"MADS-box regulators of differentiation, MEF-2"
			},
			{
				"name":"MADS-box regulators of differentiation, Homeotic genes"
			},
			{
				"name":"MADS-box regulators of differentiation, Yeast regulators"
			},
			{
				"name":"MADS-box responders to external signals"
			},
			{
				"name":"SAND domain-containing proteins"
			},
			{
				"name":"TATA-binding proteins"
			},
			{
				"name":"HMG SOX"
			},
			{
				"name":"HMG TCF-1"
			},
			{
				"name":"HMG TOX"
			},
			{
				"name":"HMG2-related"
			},
			{
				"name":"UBF"
			},
			{
				"name":"Other HMG box factors"
			},
			{
				"name":"Heteromeric CCAAT factors"
			},
			{
				"name":"Grainyhead"
			},
			{
				"name":"Cold-shock domain factors, DbpA-like"
			},
			{
				"name":"Cold-shock domain factors, YB-1\/DbpB-like"
			},
			{
				"name":"Cold-shock domain factors, FRG Y2-like"
			},
			{
				"name":"Runt"
			},
			{
				"name":"MYRF"
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"HMGI(Y)"
			},
			{
				"name":"NUPR"
			},
			{
				"name":"Pocket domain Rb"
			},
			{
				"name":"Pocket domain CBP"
			},
			{
				"name":"T-box"
			},
			{
				"name":"DMRT"
			},
			{
				"name":"LRRFIP"
			},
			{
				"name":"TCP"
			},
			{
				"name":"AP2\/ERF"
			},
			{
				"name":"WRKY"
			},
			{
				"name":"LOB"
			},
			{
				"name":"GRAS"
			},
			{
				"name":"NAC"
			},
			{
				"name":"Copper-fist proteins fungal regulators"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Helix-turn-helix",
			"children":[
			{
				"name":"AraC family",
				"children":[
				{
					"name":"AX767_07155 hypothetical protein\tK18991 mtrA; AraC family transcriptional regulator, activator of mtrCDE"
				},
				{
					"name":"AX767_03330 adenosine deaminase\tK13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response \/ DNA-3-methyladenine glycosylase II [EC:3.2.2.21]"
				}
				]
			},
			{
				"name":"LysR family",
				"children":[
				{
					"name":"AX767_06225 LysR family transcriptional regulator\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"AX767_20540 LysR family transcriptional regulator\tK03566 gcvA; LysR family transcriptional regulator, glycine cleavage system transcriptional activator"
				},
				{
					"name":"AX767_13820 LysR family transcriptional regulator\tK02623 pcaQ; LysR family transcriptional regulator, pca operon transcriptional activator"
				},
				{
					"name":"AX767_09065 LysR family transcriptional regulator\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA"
				},
				{
					"name":"AX767_12920 LysR family transcriptional regulator\tK03717 nhaR; LysR family transcriptional regulator, transcriptional activator of nhaA"
				},
				{
					"name":"AX767_08170 LysR family transcriptional regulator\tK04761 oxyR; LysR family transcriptional regulator, hydrogen peroxide-inducible genes activator"
				},
				{
					"name":"AX767_07990 LysR family transcriptional regulator\tK05596 argP; LysR family transcriptional regulator, arginine and lysine transport system\/DNA replication regulator"
				},
				{
					"name":"AX767_19410 transcriptional regulator\tK13634 cysB; LysR family transcriptional regulator, cys regulon transcriptional activator"
				},
				{
					"name":"AX767_16615 LysR family transcriptional regulator\tK14057 abgR; LysR family transcriptional regulator, regulator of abg operon"
				},
				{
					"name":"AX767_16800 LysR family transcriptional regulator\tK16135 dmlR; LysR family transcriptional regulator, transcriptional activator for dmlA"
				},
				{
					"name":"AX767_01775 LysR family transcriptional regulator\tK17737 dhcR; LysR family transcriptional regulator, carnitine catabolism transcriptional activator"
				},
				{
					"name":"AX767_18620 LysR family transcriptional regulator\tK18900 bpeT; LysR family transcriptional regulator, regulator for bpeEF and oprC"
				},
				{
					"name":"AX767_07250 LysR family transcriptional regulator\tK21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT"
				},
				{
					"name":"AX767_16565 LysR family transcriptional regulator\tK21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT"
				},
				{
					"name":"AX767_17530 LysR family transcriptional regulator\tK21645 hypT; LysR family transcriptional regulator, hypochlorite-specific transcription factor HypT"
				}
				]
			},
			{
				"name":"DeoR family",
				"children":[
				{
					"name":"AX767_01905 DeoR family transcriptional regulator\tK02444 glpR; DeoR family transcriptional regulator, glycerol-3-phosphate regulon repressor"
				}
				]
			},
			{
				"name":"LacI family",
				"children":[
				{
					"name":"AX767_13630 LacI family transcriptional regulator\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"AX767_19920 hypothetical protein\tK02529 galR; LacI family transcriptional regulator, galactose operon repressor"
				},
				{
					"name":"AX767_01990 dehydrogenase\tK02525 kdgR; LacI family transcriptional regulator, kdg operon repressor"
				}
				]
			},
			{
				"name":"GntR family",
				"children":[
				{
					"name":"AX767_06175 phosphonate metabolism transcriptional regulator PhnF\tK02043 phnF; GntR family transcriptional regulator, phosphonate transport system regulatory protein"
				},
				{
					"name":"AX767_09955 histidine utilization repressor\tK05836 hutC; GntR family transcriptional regulator, histidine utilization repressor"
				},
				{
					"name":"AX767_01680 hypothetical protein\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"AX767_15280 GntR family transcriptional regulator\tK03710 K03710; GntR family transcriptional regulator"
				},
				{
					"name":"AX767_11640 GntR family transcriptional regulator\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"AX767_20020 DNA-binding protein\tK00375 K00375; GntR family transcriptional regulator \/ MocR family aminotransferase"
				},
				{
					"name":"AX767_16430 GntR family transcriptional regulator\tK11475 vanR; GntR family transcriptional regulator, vanillate catabolism transcriptional regulator"
				}
				]
			},
			{
				"name":"TetR\/AcrR family",
				"children":[
				{
					"name":"AX767_07385 dihydroorotate oxidase\tK05501 slmA; TetR\/AcrR family transcriptional regulator"
				},
				{
					"name":"AX767_14300 hypothetical protein\tK19736 aefR; TetR\/AcrR family transcriptional regulator, regulator of autoinduction and epiphytic fitness"
				},
				{
					"name":"AX767_09795 TetR family transcriptional regulator\tK22294 nicS; TetR\/AcrR family transcriptional regulator, upper aerobic nicotinate degradation pathway regulator"
				},
				{
					"name":"AX767_18285 TetR family transcriptional regulator\tK23777 cecR; TetR\/AcrR family transcriptional regulator, regulator of cefoperazone and chloramphenicol sensitivity"
				}
				]
			},
			{
				"name":"Lrp\/AsnC family",
				"children":[
				{
					"name":"AX767_06195 AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"AX767_08450 ArsR family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"AX767_11315 AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"AX767_16685 AsnC family transcriptional regulator\tK03719 lrp; Lrp\/AsnC family transcriptional regulator, leucine-responsive regulatory protein"
				},
				{
					"name":"AX767_01585 ArsR family transcriptional regulator\tK05800 decR; Lrp\/AsnC family transcriptional regulator, cysteine-sensing transcriptional activator"
				}
				]
			},
			{
				"name":"LuxR family"
			},
			{
				"name":"MarR family",
				"children":[
				{
					"name":"AX767_07730 MarR family transcriptional regulator\tK23775 ohrR; MarR family transcriptional regulator, organic hydroperoxide resistance regulator"
				}
				]
			},
			{
				"name":"MerR family",
				"children":[
				{
					"name":"AX767_10360 MerR family transcriptional regulator\tK19591 cueR; MerR family transcriptional regulator, copper efflux regulator"
				},
				{
					"name":"AX767_18170 MerR family transcriptional regulator\tK13639 soxR; MerR family transcriptional regulator, redox-sensitive transcriptional activator SoxR"
				}
				]
			},
			{
				"name":"Fur family",
				"children":[
				{
					"name":"AX767_11790 Fur family transcriptional regulator\tK03711 fur; Fur family transcriptional regulator, ferric uptake regulator"
				}
				]
			},
			{
				"name":"IclR family",
				"children":[
				{
					"name":"AX767_13835 IclR family transcriptional regulator\tK02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein"
				},
				{
					"name":"AX767_20590 IclR family transcriptional regulator\tK02624 pcaR; IclR family transcriptional regulator, pca regulon regulatory protein"
				}
				]
			},
			{
				"name":"CRP\/FNR family",
				"children":[
				{
					"name":"AX767_00555 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_01705 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_07940 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_08605 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_09475 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_11420 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_14610 hypothetical protein\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_17845 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_18970 Crp\/Fnr family transcriptional regulator\tK10914 crp; CRP\/FNR family transcriptional regulator, cyclic AMP receptor protein"
				},
				{
					"name":"AX767_06210 Crp\/Fnr family transcriptional regulator\tK01420 fnr; CRP\/FNR family transcriptional regulator, anaerobic regulatory protein"
				}
				]
			},
			{
				"name":"Rrf2 family",
				"children":[
				{
					"name":"AX767_00985 DNA-binding protein\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				},
				{
					"name":"AX767_14130 DNA-binding protein\tK13643 iscR; Rrf2 family transcriptional regulator, iron-sulfur cluster assembly transcription factor"
				}
				]
			},
			{
				"name":"ArsR family",
				"children":[
				{
					"name":"AX767_06495 ArsR family transcriptional regulator\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"AX767_09875 hypothetical protein\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"AX767_17460 ArsR family transcriptional regulator\tK03892 arsR; ArsR family transcriptional regulator, arsenate\/arsenite\/antimonite-responsive transcriptional repressor"
				},
				{
					"name":"AX767_03480 ArsR family transcriptional regulator\tK22042 hlyU; ArsR family transcriptional regulator, virulence genes transcriptional regulator"
				}
				]
			},
			{
				"name":"XRE family"
			},
			{
				"name":"PadR family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"AX767_10985 biotin--acetyl-CoA-carboxylase ligase\tK03524 birA; BirA family transcriptional regulator, biotin operon repressor \/ biotin---[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]"
				},
				{
					"name":"AX767_13670 Fis family transcriptional regulator\tK03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein"
				},
				{
					"name":"AX767_20570 propionate catabolism operon regulatory protein PrpR\tK02688 prpR; transcriptional regulator, propionate catabolism operon regulatory protein"
				},
				{
					"name":"AX767_07830 transcriptional regulator\tK06211 nadR; HTH-type transcriptional regulator, transcriptional repressor of NAD biosynthesis genes [EC:2.7.7.1 2.7.1.22]"
				},
				{
					"name":"AX767_18690 hypothetical protein\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"AX767_20245 addiction module antidote protein\tK15773 hipB; HTH-type transcriptional regulator \/ antitoxin HipB"
				},
				{
					"name":"AX767_15765 hypothetical protein\tK02019 modE; molybdate transport system regulatory protein"
				},
				{
					"name":"AX767_01945 XRE family transcriptional regulator\tK07726 K07726; putative transcriptional regulator"
				},
				{
					"name":"AX767_00430 XRE family transcriptional regulator\tK07729 K07729; putative transcriptional regulator"
				}
				]
			}
			]
		},
		{
			"name":"Ribbon-helix-helix",
			"children":[
			{
				"name":"CopG family"
			},
			{
				"name":"Other families",
				"children":[
				{
					"name":"AX767_08445 integrase\tK13821 putA; RHH-type transcriptional regulator, proline utilization regulon repressor \/ proline dehydrogenase \/ delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]"
				}
				]
			}
			]
		},
		{
			"name":"Other transcription factors",
			"children":[
			{
				"name":"BglG family"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"AX767_16285 regulator\tK23239 frmR; FrmR\/RcnR family transcriptional regulator, repressor of frmRAB operon"
				},
				{
					"name":"AX767_20175 BolA family transcriptional regulator\tK05527 bolA; BolA family transcriptional regulator, general stress-responsive regulator"
				},
				{
					"name":"AX767_10240 chromosome partitioning protein ParB\tK03497 parB; ParB family transcriptional regulator, chromosome partitioning protein"
				},
				{
					"name":"AX767_14235 heat-inducible transcriptional repressor HrcA\tK03705 hrcA; heat-inducible transcriptional repressor"
				},
				{
					"name":"AX767_10520 transcription elongation factor GreAB\tK06140 rnk; regulator of nucleoside diphosphate kinase"
				},
				{
					"name":"AX767_13740 bifunctional pyr operon transcriptional regulator\/uracil phosphoribosyltransferase\tK02825 pyrR; pyrimidine operon attenuation protein \/ uracil phosphoribosyltransferase [EC:2.4.2.9]"
				},
				{
					"name":"AX767_07015 negative transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"AX767_19780 transcriptional regulator\tK07734 paiB; transcriptional regulator"
				},
				{
					"name":"AX767_13730 hypothetical protein\tK07735 algH; putative transcriptional regulator"
				},
				{
					"name":"AX767_03805 hypothetical protein\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"AX767_06980 conjugal transfer protein TraR\tK06204 dksA; RNA polymerase-binding transcription factor"
				},
				{
					"name":"AX767_18080 NrdR family transcriptional regulator\tK07738 nrdR; transcriptional repressor NrdR"
				},
				{
					"name":"AX767_06960 division\/cell wall cluster transcriptional repressor MraZ\tK03925 mraZ; transcriptional regulator MraZ"
				}
				]
			}
			]
		}
		]
	}
	]
}