{
	"name":"val01009",
	"children":[
	{
		"name":"Protein serine\/threonine phosphatases",
		"children":[
		{
			"name":"Phosphoprotein phosphatases (PPPs)",
			"children":[
			{
				"name":"Protein phosphatase-1",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"VDBG_07352 serine\/threonine-protein phosphatase PP-Z\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"VDBG_08759 serine\/threonine-protein phosphatase PP1\tK06269 PPP1C; serine\/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP1-interacting proteins (PIPs)",
					"children":[
					{
						"name":"VDBG_06452 hypothetical protein\tK16833 PPP1R2; protein phosphatase inhibitor 2"
					},
					{
						"name":"VDBG_03847 protein phosphatase 1 regulatory subunit SDS22\tK17550 PPP1R7; protein phosphatase 1 regulatory subunit 7"
					},
					{
						"name":"VDBG_07206 hypothetical protein\tK17560 URI1; unconventional prefoldin RPB5 interactor 1"
					},
					{
						"name":"VDBG_05196 hypothetical protein\tK13099 CD2BP2; CD2 antigen cytoplasmic tail-binding protein 2"
					},
					{
						"name":"VDBG_04836 kinesin-II 95 kDa subunit\tK11498 CENPE; centromeric protein E"
					},
					{
						"name":"VDBG_00319 eukaryotic translation initiation factor 2 subunit beta\tK03238 EIF2S2; translation initiation factor 2 subunit 2"
					},
					{
						"name":"VDBG_03767 COM1\tK15183 ELL; RNA polymerase II elongation factor ELL"
					},
					{
						"name":"VDBG_01432 adenosylhomocysteinase\tK01251 AHCY; adenosylhomocysteinase [EC:3.13.2.1]"
					},
					{
						"name":"VDBG_07586 histone demethylase JARID1A\tK11446 KDM5; [histone H3]-trimethyl-L-lysine4 demethylase [EC:1.14.11.67]"
					},
					{
						"name":"VDBG_04277 60S ribosomal protein L5\tK02932 RP-L5e; large subunit ribosomal protein L5e"
					},
					{
						"name":"VDBG_04696 DNA replication licensing factor mcm7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
					},
					{
						"name":"VDBG_07170 myosin-5\tK10356 MYO1; myosin I"
					},
					{
						"name":"VDBG_01832 G2-specific protein kinase nim-1\tK20872 NEK2; serine\/threonine-protein kinase Nek2 [EC:2.7.11.1]"
					},
					{
						"name":"VDBG_09694 suppressor of glycerol defect protein\tK17583 NOM1; nucleolar MIF4G domain-containing protein 1"
					},
					{
						"name":"VDBG_09695 hypothetical protein\tK17583 NOM1; nucleolar MIF4G domain-containing protein 1"
					},
					{
						"name":"VDBG_01664 6-phosphofructokinase\tK00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]"
					},
					{
						"name":"VDBG_01424 rRNA processing protein RRP1\tK14849 RRP1; ribosomal RNA-processing protein 1"
					},
					{
						"name":"VDBG_06781 transcription regulatory protein SNF5\tK11648 SMARCB1; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1"
					},
					{
						"name":"VDBG_00241 vacuolar protein sorting-associated protein\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-2 (PP2A)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"VDBG_00932 serine\/threonine-protein phosphatase PP2A catalytic subunit\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"VDBG_08720 protein phosphatase PP2A regulatory subunit A\tK03456 PPP2R1; serine\/threonine-protein phosphatase 2A regulatory subunit A"
					},
					{
						"name":"VDBG_05099 protein phosphatase PP2A regulatory subunit B\tK04354 PPP2R2; serine\/threonine-protein phosphatase 2A regulatory subunit B"
					},
					{
						"name":"VDBG_04046 serine\/threonine-protein phosphatase 2A\tK11584 PPP2R5; serine\/threonine-protein phosphatase 2A regulatory subunit B'"
					}
					]
				},
				{
					"name":"Other PP2-interacting proteins",
					"children":[
					{
						"name":"VDBG_05848 serine\/threonine-protein phosphatase 2A activator 2\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"VDBG_07898 serine\/threonine-protein phosphatase 2A activator 1\tK17605 PPP2R4; serine\/threonine-protein phosphatase 2A activator"
					},
					{
						"name":"VDBG_00863 TapA protein\tK17606 IGBP1; immunoglobulin-binding protein 1"
					},
					{
						"name":"VDBG_08832 type 2A phosphatase activator TIP41\tK17607 TIPRL; type 2A phosphatase activator TIP41"
					},
					{
						"name":"VDBG_05450 striatin Pro11\tK17608 STRN1_3_4; striatin 1\/3\/4"
					},
					{
						"name":"VDBG_04223 HAM-2\tK27960 STRIP; striatin-interacting protein"
					}
					]
				}
				]
			},
			{
				"name":"Calcineurin (PPP3\/ PP2B)",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"VDBG_00079 serine\/threonine-protein phosphatase 2B catalytic subunit\tK04348 PPP3C; serine\/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"VDBG_00062 calcineurin subunit B\tK06268 PPP3R; serine\/threonine-protein phosphatase 2B regulatory subunit"
					},
					{
						"name":"VDBG_04469 calmodulin\tK02183 CALM; calmodulin"
					},
					{
						"name":"VDBG_09353 calmodulin\tK02183 CALM; calmodulin"
					}
					]
				},
				{
					"name":"Other calcineurin-interacting proteins"
				}
				]
			},
			{
				"name":"Protein phosphatase-4",
				"children":[
				{
					"name":"Catalytic subunits"
				},
				{
					"name":"Regulatory subunits",
					"children":[
					{
						"name":"VDBG_01614 suppressor of Mek1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-5",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"VDBG_00071 serine\/threonine-protein phosphatase\tK04460 PPP5C; serine\/threonine-protein phosphatase 5 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"PP5-interacting proteins",
					"children":[
					{
						"name":"VDBG_06806 bimA\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"VDBG_04104 anaphase-promoting complex subunit cut9\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"VDBG_09407 heat shock protein\tK04079 HSP90A; molecular chaperone HtpG"
					},
					{
						"name":"VDBG_03874 heat shock protein SSB1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					},
					{
						"name":"VDBG_05260 hsp70-like protein\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
					}
					]
				}
				]
			},
			{
				"name":"Protein phosphatase-6",
				"children":[
				{
					"name":"Catalytic subunits",
					"children":[
					{
						"name":"VDBG_01534 serine\/threonine-protein phosphatase PP1-1\tK15427 SIT4; serine\/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]"
					},
					{
						"name":"VDBG_01347 serine\/threonine-protein phosphatase PP2A-3 catalytic subunit\tK17615 PPG1; serine\/threonine-protein phosphatase PPG1 [EC:3.1.3.16]"
					}
					]
				},
				{
					"name":"Regulatory subunits"
				}
				]
			},
			{
				"name":"PPEF\/PP7 protein phosphatases"
			}
			]
		},
		{
			"name":"Mg2+- or Mn2+- dependent protein phosphatases (PPMs)",
			"children":[
			{
				"name":"PPM1 phosphatases (PP2C)",
				"children":[
				{
					"name":"VDBG_07829 protein phosphatase 1A\tK19704 PTC1; protein phosphatase PTC1 [EC:3.1.3.16]"
				},
				{
					"name":"VDBG_00405 protein phosphatase 1G\tK14803 PTC2_3; protein phosphatase PTC2\/3 [EC:3.1.3.16]"
				},
				{
					"name":"VDBG_04896 hypothetical protein\tK17508 PTC7; protein phosphatase PTC7 [EC:3.1.3.16]"
				}
				]
			},
			{
				"name":"Pyruvate dehydrogenase phosphatases",
				"children":[
				{
					"name":"Catalytic subunit",
					"children":[
					{
						"name":"VDBG_05225 phosphatase\tK01102 PDP; pyruvate dehydrogenase phosphatase [EC:3.1.3.43]"
					}
					]
				},
				{
					"name":"Regulatory subunit"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein tyrosine phosphatases (PTPs)",
		"children":[
		{
			"name":"Class I PTPs (Classical)",
			"children":[
			{
				"name":"Receptor PTPs"
			},
			{
				"name":"Non-receptor PTPs",
				"children":[
				{
					"name":"VDBG_05505 tyrosine-protein phosphatase non-receptor\tK19806 PTP2_3; tyrosine-protein phosphatase 2\/3 [EC:3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class I PTPs (Dual specificity phosphatases)",
			"children":[
			{
				"name":"MAPK phosphatases",
				"children":[
				{
					"name":"VDBG_03420 pps1 dual specificty phosphatase\tK04459 DUSP2S; dual specificity protein phosphatase [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"VDBG_08838 tyrosine-protein phosphatase pmp1\tK11240 MSG5; tyrosine-protein phosphatase MSG5 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"Slingshots"
			},
			{
				"name":"Phosphatase of regenerating liver (PRL)"
			},
			{
				"name":"Atypical DSPs",
				"children":[
				{
					"name":"VDBG_02851 dual specificity protein phosphatase\tK14819 DUSP12; dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48]"
				},
				{
					"name":"VDBG_00883 FMI2 protein\tK18042 STYX; serine\/threonine\/tyrosine-interacting protein"
				},
				{
					"name":"VDBG_05814 tyrosine-protein phosphatase SIW14\tK18045 SIW14; tyrosine-protein phosphatase SIW14 [EC:3.1.3.48]"
				}
				]
			},
			{
				"name":"CDC14",
				"children":[
				{
					"name":"VDBG_05999 tyrosine-protein phosphatase CDC14\tK06639 CDC14; cell division cycle 14 [EC:3.1.3.16 3.1.3.48]"
				}
				]
			},
			{
				"name":"Phosphatase and Tensin homologs (PTEN)"
			},
			{
				"name":"Myotubularins",
				"children":[
				{
					"name":"VDBG_08718 myotubularin\tK18083 MTMR6_7_8; myotubularin-related protein 6\/7\/8 [EC:3.1.3.64 3.1.3.95]"
				}
				]
			},
			{
				"name":"Suppressors of T-cell receptor signaling"
			}
			]
		},
		{
			"name":"Class II PTPs",
			"children":[
			{
				"name":"Low molecular weight PTPs (LMWPTPs)",
				"children":[
				{
					"name":"VDBG_02118 phosphotyrosine protein phosphatase\tK14394 ACP1; low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48]"
				}
				]
			}
			]
		},
		{
			"name":"Class III PTPs",
			"children":[
			{
				"name":"CDC25s",
				"children":[
				{
					"name":"VDBG_05031 M-phase inducer phosphatase\tK02555 MIH1; M-phase inducer tyrosine phosphatase [EC:3.1.3.48]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"HAD phosphatases",
		"children":[
		{
			"name":"Fcp\/Scp phosphatases",
			"children":[
			{
				"name":"VDBG_09811 RNA polymerase II subunit A C-terminal domain phosphatase\tK15732 CTDP1; RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"VDBG_03840 phosphatase PSR1\tK15731 CTDSP; carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16]"
			},
			{
				"name":"VDBG_00601 nuclear envelope morphology protein\tK17617 CTDNEP1; CTD nuclear envelope phosphatase 1 [EC:3.1.3.16]"
			},
			{
				"name":"VDBG_08253 DUF408 domain-containing protein\tK20827 RPAP2; RNA polymerase II-associated protein 2 [EC:3.1.3.16]"
			}
			]
		},
		{
			"name":"MDP-1",
			"children":[
			{
				"name":"VDBG_01201 magnesium-dependent phosphatase\tK17619 MDP1; magnesium-dependent phosphatase 1 [EC:3.1.3.48 3.1.3.-]"
			}
			]
		},
		{
			"name":"EYAs"
		},
		{
			"name":"Other HAD phosphatases",
			"children":[
			{
				"name":"VDBG_02956 bifunctional polynucleotide phosphatase\/kinase\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
			},
			{
				"name":"VDBG_05347 epoxide hydrolase\tK08726 EPHX2; soluble epoxide hydrolase \/ lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]"
			},
			{
				"name":"VDBG_08907 epoxide hydrolase\tK08726 EPHX2; soluble epoxide hydrolase \/ lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]"
			},
			{
				"name":"VDBG_06462 phosphoserine phosphatase\tK01079 serB; phosphoserine phosphatase [EC:3.1.3.3]"
			},
			{
				"name":"VDBG_08375 GS1 protein\tK17623 PUDP; pseudouridine 5'-phosphatase [EC:3.1.3.96]"
			},
			{
				"name":"VDBG_07233 nuclear elongation and deformation protein\tK15728 LPIN; phosphatidate phosphatase LPIN [EC:3.1.3.4]"
			},
			{
				"name":"VDBG_00881 phosphorylcholine phosphatase\tK21830 pchP; phosphoethanolamine\/phosphocholine phosphatase [EC:3.1.3.75]"
			}
			]
		}
		]
	}
	]
}