{
	"name":"vbr03009",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"90S particles",
			"children":[
			{
				"name":"U3 small nucleolar RNA-associated proteins"
			},
			{
				"name":"Helicases"
			},
			{
				"name":"GTPase"
			},
			{
				"name":"RNase",
				"children":[
				{
					"name":"A6E01_10900 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
				}
				]
			},
			{
				"name":"Kinase"
			},
			{
				"name":"Other 90S particles"
			}
			]
		},
		{
			"name":"Pre-40S particles",
			"children":[
			{
				"name":"Kinases",
				"children":[
				{
					"name":"A6E01_13555 kinase\tK07178 RIOK1; RIO kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"Other pre-40S particles"
			}
			]
		},
		{
			"name":"Pre-60S particles",
			"children":[
			{
				"name":"Helicases"
			},
			{
				"name":"GTPases"
			},
			{
				"name":"RNases",
				"children":[
				{
					"name":"A6E01_11955 oligoribonuclease\tK13288 orn; oligoribonuclease [EC:3.1.-.-]"
				},
				{
					"name":"RNase MRP"
				}
				]
			},
			{
				"name":"Kinases"
			},
			{
				"name":"Export and cytoplasmic maturation factors"
			},
			{
				"name":"55LCC heterohexameric ATPase complex"
			},
			{
				"name":"5-FMC complex"
			},
			{
				"name":"Ribosome quality control proteins"
			},
			{
				"name":"Other pre-60S particles"
			}
			]
		},
		{
			"name":"Other ribosome biogenesis factors",
			"children":[
			{
				"name":"A6E01_10895 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"A6E01_01555 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"Sno RNPs",
			"children":[
			{
				"name":"Box C\/D snoRNPs"
			},
			{
				"name":"Box H\/ACA snoRNPs"
			}
			]
		},
		{
			"name":"rRNA transcription factors",
			"children":[
			{
				"name":"A6E01_10550 RNA polymerase-binding protein DksA\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"A6E01_20820 hypothetical protein\tK06204 dksA; RNA polymerase-binding transcription factor"
			},
			{
				"name":"A6E01_02695 nusA; transcription termination\/antitermination protein NusA\tK02600 nusA; transcription termination\/antitermination protein NusA"
			},
			{
				"name":"A6E01_09875 N utilization substance protein B\tK03625 nusB; transcription antitermination protein NusB"
			},
			{
				"name":"A6E01_12435 nusG; transcription termination\/antitermination protein NusG\tK02601 nusG; transcription termination\/antitermination protein NusG"
			}
			]
		},
		{
			"name":"rRNA modification factors",
			"children":[
			{
				"name":"16S rRNA modification factors",
				"children":[
				{
					"name":"A6E01_06165 16S rRNA pseudouridine(516) synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"A6E01_07170 16S rRNA pseudouridine(516) synthase\tK06183 rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]"
				},
				{
					"name":"A6E01_01590 16S rRNA (adenine(1518)-N(6)\/adenine(1519)-N(6))-dimethyltransferase\tK02528 ksgA; 16S rRNA (adenine1518-N6\/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]"
				},
				{
					"name":"A6E01_00210 16S rRNA (cytosine(967)-C(5))-methyltransferase\tK03500 rsmB; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]"
				},
				{
					"name":"A6E01_10435 16S rRNA methyltransferase\tK00564 rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]"
				},
				{
					"name":"A6E01_12650 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD\tK08316 rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]"
				},
				{
					"name":"A6E01_11050 16S rRNA (uracil(1498)-N(3))-methyltransferase\tK09761 rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]"
				},
				{
					"name":"A6E01_06680 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF\tK11392 rsmF; 16S rRNA (cytosine1407-C5)-methyltransferase [EC:2.1.1.178]"
				},
				{
					"name":"A6E01_00055 16S rRNA (guanine(527)-N(7))-methyltransferase\tK03501 gidB; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]"
				},
				{
					"name":"A6E01_02050 16S rRNA (cytosine(1402)-N(4))-methyltransferase\tK03438 mraW; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]"
				},
				{
					"name":"A6E01_02040 16S rRNA (cytidine(1402)-2'-O)-methyltransferase\tK07056 rsmI; 16S rRNA (cytidine1402-2'-O)-methyltransferase [EC:2.1.1.198]"
				},
				{
					"name":"A6E01_00480 16S rRNA methyltransferase\tK15984 rsmJ; 16S rRNA (guanine1516-N2)-methyltransferase [EC:2.1.1.242]"
				}
				]
			},
			{
				"name":"23S rRNA modification factors",
				"children":[
				{
					"name":"A6E01_08400 rrmA; 23S rRNA (guanine(745)-N(1))-methyltransferase\tK00563 rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]"
				},
				{
					"name":"A6E01_11835 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB\tK03218 rlmB; 23S rRNA (guanosine2251-2'-O)-methyltransferase [EC:2.1.1.185]"
				},
				{
					"name":"A6E01_10365 23S rRNA (uridine(2552)-2'-O)-methyltransferase\tK02427 rlmE; 23S rRNA (uridine2552-2'-O)-methyltransferase [EC:2.1.1.166]"
				},
				{
					"name":"A6E01_08950 23S rRNA (adenine(1618)-N(6))-methyltransferase\tK06970 rlmF; 23S rRNA (adenine1618-N6)-methyltransferase [EC:2.1.1.181]"
				},
				{
					"name":"A6E01_03130 50S rRNA methyltransferase\tK11391 rlmG; 23S rRNA (guanine1835-N2)-methyltransferase [EC:2.1.1.174]"
				},
				{
					"name":"A6E01_03305 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH\tK00783 rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]"
				},
				{
					"name":"A6E01_05555 methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"A6E01_06755 23S rRNA methyltransferase\tK06969 rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]"
				},
				{
					"name":"A6E01_00465 rRNA methyltransferase\tK07115 rlmJ; 23S rRNA (adenine2030-N6)-methyltransferase [EC:2.1.1.266]"
				},
				{
					"name":"A6E01_06625 23S rRNA (guanine(2445)-N(2))\/(guanine(2069)-N(7))-methyltransferase\tK12297 rlmKL; 23S rRNA (guanine2069-N7)-methyltransferase \/ 23S rRNA (guanine2445-N2)-methyltransferase [EC:2.1.1.264 2.1.1.173]"
				},
				{
					"name":"A6E01_09835 23S rRNA (cytidine(2498)-2'-O)-methyltransferase RlmM\tK06968 rlmM; 23S rRNA (cytidine2498-2'-O)-methyltransferase [EC:2.1.1.186]"
				},
				{
					"name":"A6E01_10285 bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG\/ribosomal RNA large subunit methyltransferase RlmN\tK06941 rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]"
				},
				{
					"name":"A6E01_10870 rumA; 23S rRNA (uracil(1939)-C(5))-methyltransferase\tK03215 rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]"
				},
				{
					"name":"A6E01_01500 RNA pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"A6E01_05550 RNA pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"A6E01_07825 RNA pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"A6E01_18305 RNA pseudouridine synthase\tK06177 rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				},
				{
					"name":"A6E01_05660 23S rRNA pseudouridylate synthase B\tK06178 rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]"
				},
				{
					"name":"A6E01_08875 RNA pseudouridine synthase\tK06179 rluC; 23S rRNA pseudouridine955\/2504\/2580 synthase [EC:5.4.99.24]"
				},
				{
					"name":"A6E01_02455 23S rRNA pseudouridine(1911\/1915\/1917) synthase\tK06180 rluD; 23S rRNA pseudouridine1911\/1915\/1917 synthase [EC:5.4.99.23]"
				},
				{
					"name":"A6E01_05165 23S rRNA pseudouridylate synthase\tK06181 rluE; 23S rRNA pseudouridine2457 synthase [EC:5.4.99.20]"
				},
				{
					"name":"A6E01_03520 23S rRNA pseudouridine synthase F\tK06182 rluF; 23S rRNA pseudouridine2604 synthase [EC:5.4.99.21]"
				}
				]
			}
			]
		},
		{
			"name":"ribosomal protein modification factors",
			"children":[
			{
				"name":"A6E01_02770 ribosomal-protein-alanine N-acetyltransferase\tK03789 rimI; [ribosomal protein S18]-alanine N-acetyltransferase \/ [ribosomal protein L31]-L-lysine N-acetyltransferase [EC:2.3.1.266 2.3.1.338]"
			},
			{
				"name":"A6E01_06970 ribosomal-protein-alanine acetyltransferase\tK03790 rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]"
			},
			{
				"name":"A6E01_18450 ribosomal protein S6 modification protein\tK05844 rimK; ribosomal protein S6--L-glutamate ligase [EC:6.3.2.-]"
			},
			{
				"name":"A6E01_10675 rimM; ribosome maturation factor RimM\tK02860 rimM; 16S rRNA processing protein RimM"
			},
			{
				"name":"A6E01_12240 ribosomal protein L11 methyltransferase\tK02687 prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]"
			},
			{
				"name":"A6E01_08545 ribosomal protein L3 N(5)-glutamine methyltransferase\tK07320 prmB; ribosomal protein L3 glutamine methyltransferase [EC:2.1.1.298]"
			},
			{
				"name":"A6E01_05530 50S ribosomal protein L16 arginine hydroxylase\tK18850 ycfD; 50S ribosomal protein L16 3-hydroxylase [EC:1.14.11.47]"
			}
			]
		},
		{
			"name":"rRNA processing factors",
			"children":[
			{
				"name":"A6E01_10900 ribonuclease III\tK03685 rnc; ribonuclease III [EC:3.1.26.3]"
			},
			{
				"name":"A6E01_08880 ribonuclease\tK08300 rne; ribonuclease E [EC:3.1.26.12]"
			},
			{
				"name":"A6E01_11500 ribonuclease G\tK08301 rng; ribonuclease G [EC:3.1.26.-]"
			},
			{
				"name":"A6E01_11065 Holliday junction DNA helicase RuvA\tK07447 ruvX; putative pre-16S rRNA nuclease [EC:3.1.-.-]"
			}
			]
		},
		{
			"name":"rRNA helicases",
			"children":[
			{
				"name":"A6E01_16900 ATP-dependent RNA helicase DbpA\tK05591 dbpA; ATP-dependent RNA helicase DbpA [EC:5.6.2.6]"
			},
			{
				"name":"A6E01_15420 ATP-dependent RNA helicase\tK05592 deaD; ATP-dependent RNA helicase DeaD [EC:5.6.2.7]"
			},
			{
				"name":"A6E01_02280 ATP-dependent RNA helicase SrmB\tK05590 srmB; ATP-dependent RNA helicase SrmB [EC:5.6.2.7]"
			}
			]
		},
		{
			"name":"GTPases",
			"children":[
			{
				"name":"A6E01_10895 GTPase Era\tK03595 era; GTPase"
			},
			{
				"name":"A6E01_11960 ribosome biogenesis GTPase RsgA\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"A6E01_17125 ribosome small subunit-dependent GTPase A\tK06949 rsgA; ribosome biogenesis GTPase \/ thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]"
			},
			{
				"name":"A6E01_10250 ribosome biogenesis GTPase Der\tK03977 engA; GTPase"
			},
			{
				"name":"A6E01_01555 obgE; GTPase ObgE\tK03979 obgE; GTPase [EC:3.6.5.-]"
			},
			{
				"name":"A6E01_14630 ribosome biogenesis GTPase YlqF\tK14540 rbgA; ribosome biogenesis GTPase A"
			},
			{
				"name":"A6E01_11875 GTPase HflX\tK03665 hflX; GTPase"
			}
			]
		},
		{
			"name":"Other maturation factors",
			"children":[
			{
				"name":"A6E01_00250 threonylcarbamoyl-AMP synthase\tK07566 tsaC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
			},
			{
				"name":"A6E01_12350 bifunctional GTP diphosphokinase\/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase\tK01139 spoT; GTP diphosphokinase \/ guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [EC:2.7.6.5 3.1.7.2]"
			},
			{
				"name":"A6E01_02705 ribosome-binding factor A\tK02834 rbfA; ribosome-binding factor A"
			},
			{
				"name":"A6E01_02690 ribosome maturation factor RimP\tK09748 rimP; ribosome maturation factor RimP"
			},
			{
				"name":"A6E01_15400 hypothetical protein\tK14761 rlbA; ribosome-associated protein"
			},
			{
				"name":"A6E01_03310 ribosome silencing factor\tK09710 ybeB; ribosome-associated protein"
			},
			{
				"name":"A6E01_03350 rRNA maturation RNase YbeY\tK07042 ybeY; probable rRNA maturation factor"
			},
			{
				"name":"A6E01_10370 RNA-binding protein\tK07574 yhbY; RNA-binding protein"
			},
			{
				"name":"A6E01_18820 hypothetical protein\tK14762 yibL; ribosome-associated protein"
			},
			{
				"name":"A6E01_11480 hypothetical protein\tK09889 yjgA; ribosome-associated protein"
			},
			{
				"name":"A6E01_06605 ribosome modulation factor\tK03812 rmf; ribosome modulation factor"
			},
			{
				"name":"A6E01_11450 ribosomal subunit interface protein\tK05808 hpf; ribosome hibernation promoting factor"
			},
			{
				"name":"A6E01_02440 ribosomal subunit interface protein\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"A6E01_18505 ribosomal subunit interface protein\tK05809 raiA; ribosome-associated inhibitor A"
			},
			{
				"name":"A6E01_03445 redox-regulated ATPase YchF\tK06942 ychF; ribosome-binding ATPase"
			},
			{
				"name":"A6E01_08865 ribosomal protein L32p\tK07040 yceD; DUF177 domain-containing protein"
			}
			]
		}
		]
	},
	{
		"name":"Related small nucleolar RNAs",
		"children":[
		{
			"name":"Box C\/D snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for 2'-O-ribose methylation"
			}
			]
		},
		{
			"name":"Box H\/ACA snoRNAs",
			"children":[
			{
				"name":"SnoRNAs involved in processing reactions"
			},
			{
				"name":"SnoRNAs act as guides for pseudouridynation"
			}
			]
		},
		{
			"name":"Other snoRNA"
		}
		]
	}
	]
}