{
	"name":"vda04812",
	"children":[
	{
		"name":"Eukaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin filaments \/ Microfilaments",
			"children":[
			{
				"name":"Actins",
				"children":[
				{
					"name":"Actins"
				},
				{
					"name":"Actin-related proteins",
					"children":[
					{
						"name":"VDAG_00300 alpha-centractin\tK16575 ACTR1; centractin"
					},
					{
						"name":"VDAG_09057 actin\tK11662 ACTR6; actin-related protein 6"
					}
					]
				}
				]
			},
			{
				"name":"Actin-binding proteins",
				"children":[
				{
					"name":"Myosins",
					"children":[
					{
						"name":"VDAG_06810 myosin-5\tK10356 MYO1; myosin I"
					},
					{
						"name":"VDAG_08303 myosin-2\tK10357 MYO5; myosin V"
					},
					{
						"name":"VDAG_01900 myosin-11\tK10352 MYH9s; myosin heavy chain 9\/10\/11\/14"
					}
					]
				},
				{
					"name":"Arp2\/3 complex",
					"children":[
					{
						"name":"VDAG_03181 ARP2\/3 actin-organizing complex subunit Sop2\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
					},
					{
						"name":"VDAG_04262 ARP2\/3 complex 34 kDa subunit\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
					},
					{
						"name":"VDAG_07636 ARP2\/3 complex 21 kDa subunit\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
					},
					{
						"name":"VDAG_10331 ARP2\/3 complex 20 kDa subunit\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
					},
					{
						"name":"VDAG_01987 Arp2\/3 complex subunit\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
					},
					{
						"name":"VDAG_02600 actin\tK17260 ACTR2; actin-related protein 2"
					},
					{
						"name":"VDAG_07506 actin-2\tK18584 ACTR3; actin-related protein 3"
					}
					]
				},
				{
					"name":"WASP \/ WAVE",
					"children":[
					{
						"name":"VDAG_01787 hypothetical protein\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
					}
					]
				},
				{
					"name":"Formins"
				},
				{
					"name":"Profilin",
					"children":[
					{
						"name":"VDAG_08939 profilin\tK05759 PFN; profilin"
					}
					]
				},
				{
					"name":"Thymosin"
				},
				{
					"name":"ADF \/ Cofilin",
					"children":[
					{
						"name":"VDAG_08897 cofilin\tK05765 CFL; cofilin"
					},
					{
						"name":"SCMC complex"
					}
					]
				},
				{
					"name":"Gelsolin \/ villin",
					"children":[
					{
						"name":"VDAG_07736 Gelsolin repeat-containing protein\tK05768 GSN; gelsolin"
					}
					]
				},
				{
					"name":"Ezrin\/Radixin\/Moesin"
				},
				{
					"name":"Capping proteins",
					"children":[
					{
						"name":"VDAG_01574 F-actin-capping protein subunit alpha\tK10364 CAPZA; F-actin-capping protein subunit alpha"
					},
					{
						"name":"VDAG_04499 F-actin-capping protein subunit beta\tK10365 CAPZB; F-actin-capping protein subunit beta"
					}
					]
				},
				{
					"name":"Tropomyosins",
					"children":[
					{
						"name":"VDAG_01421 tropomyosin\tK17945 TPM1_2; tropomyosin, fungi type"
					}
					]
				},
				{
					"name":"Troponins"
				},
				{
					"name":"Cross-linking proteins",
					"children":[
					{
						"name":"VDAG_06551 coronin\tK13886 CORO1B_1C_6; coronin-1B\/1C\/6"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"VDAG_05727 calponin\tK20526 TAGLN; transgelin"
					},
					{
						"name":"VDAG_01012 RasGAP-like protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
					},
					{
						"name":"VDAG_06390 fyv-10\tK18624 MAEA; macrophage erythroblast attacher"
					},
					{
						"name":"VDAG_06679 fimbrin\tK17275 PLS1; plastin-1"
					},
					{
						"name":"VDAG_07132 coactosin\tK28102 COTL1; coactosin"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Intermediate filaments",
			"children":[
			{
				"name":"Intermediate filaments",
				"children":[
				{
					"name":"Types I and II: Acidic and basic keratins"
				},
				{
					"name":"Type III"
				},
				{
					"name":"Type IV"
				},
				{
					"name":"Type V: Nuclear lamins"
				},
				{
					"name":"Type VI"
				},
				{
					"name":"Others"
				}
				]
			},
			{
				"name":"Intermediate filament-binding proteins"
			}
			]
		},
		{
			"name":"Microtubules",
			"children":[
			{
				"name":"Tubulins",
				"children":[
				{
					"name":"VDAG_03302 tubulin alpha chain\tK07374 TUBA; tubulin alpha"
				},
				{
					"name":"VDAG_04060 tubulin alpha chain\tK07374 TUBA; tubulin alpha"
				},
				{
					"name":"VDAG_05175 tubulin beta-3 chain\tK07375 TUBB; tubulin beta"
				},
				{
					"name":"VDAG_10074 tubulin beta chain\tK07375 TUBB; tubulin beta"
				},
				{
					"name":"VDAG_01827 tubulin gamma chain\tK10389 TUBG; tubulin gamma"
				}
				]
			},
			{
				"name":"Tubulin-binding proteins",
				"children":[
				{
					"name":"Kinesins",
					"children":[
					{
						"name":"VDAG_00150 kinesin-II 85 kDa subunit\tK10392 KIF1; kinesin family member 1"
					},
					{
						"name":"VDAG_07634 diatom spindle kinesin 1\tK10393 KIF2_24; kinesin family member 2\/24"
					},
					{
						"name":"VDAG_09024 kinesin heavy chain\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
					},
					{
						"name":"VDAG_06098 kinesin-II 85 kDa subunit\tK10398 KIF11; kinesin family member 11"
					},
					{
						"name":"VDAG_06209 kinesin heavy chain\tK10401 KIF18A; kinesin family member 18A"
					},
					{
						"name":"VDAG_04622 carboxy-terminal kinesin 2\tK10405 KIFC1; kinesin family member C1 (minus-end-directed kinesin ATPase) [EC:5.6.1.4]"
					}
					]
				},
				{
					"name":"Stathmin"
				},
				{
					"name":"Microtubule severing proteins"
				},
				{
					"name":"EMAP"
				},
				{
					"name":"Dyneins",
					"children":[
					{
						"name":"VDAG_00518 dynein heavy chain\tK10413 DYNC1H; dynein cytoplasmic 1 heavy chain"
					},
					{
						"name":"VDAG_02757 dynein light intermediate chain\tK10416 DYNC1LI; dynein cytoplasmic 1 light intermediate chain"
					},
					{
						"name":"VDAG_01000 dynein light chain\tK10418 DYNLL; dynein light chain LC8-type"
					},
					{
						"name":"Dynein-related proteins"
					}
					]
				},
				{
					"name":"Dynactins",
					"children":[
					{
						"name":"VDAG_07008 dynactin\tK04648 DCTN1; dynactin 1"
					},
					{
						"name":"VDAG_03592 dynactin Arp1 p62 subunit RO2\tK10426 DCTN4; dynactin 4"
					},
					{
						"name":"VDAG_02574 dynactin subunit 5\tK10427 DCTN5; dynactin 5"
					},
					{
						"name":"VDAG_05452 hypothetical protein\tK10428 DCTN6; dynactin 6"
					},
					{
						"name":"VDAG_04511 hypothetical protein\tK18599 JNM1; nuclear migration protein JNM1"
					}
					]
				},
				{
					"name":"Gamma-tubulin complex components",
					"children":[
					{
						"name":"VDAG_08990 spindle pole body component alp4\tK16569 TUBGCP2; gamma-tubulin complex component 2"
					},
					{
						"name":"VDAG_08659 spindle pole body component alp6\tK16570 TUBGCP3; gamma-tubulin complex component 3"
					},
					{
						"name":"VDAG_08419 hypothetical protein\tK16572 TUBGCP5; gamma-tubulin complex component 5"
					}
					]
				},
				{
					"name":"XMAP215",
					"children":[
					{
						"name":"VDAG_10219 spindle pole body component alp14\tK24394 STU2; protein STU2"
					}
					]
				},
				{
					"name":"Cytoplasmic linker proteins (CLIPs)",
					"children":[
					{
						"name":"CLIP-associating proteins",
						"children":[
						{
							"name":"VDAG_00451 STU1 protein\tK16578 CLASP1_2; CLIP-associating protein 1\/2"
						}
						]
					}
					]
				},
				{
					"name":"Fused toes protein (FTS)"
				},
				{
					"name":"Hook proteins",
					"children":[
					{
						"name":"VDAG_01230 hypothetical protein\tK16536 HOOK3; protein HOOK3"
					}
					]
				},
				{
					"name":"FTS and Hook-interacting proteins (FHIP)"
				},
				{
					"name":"EB \/ APC",
					"children":[
					{
						"name":"VDAG_03578 microtubule-associated protein RP\/EB family member 1\tK10436 MAPRE; microtubule-associated protein, RP\/EB family"
					}
					]
				},
				{
					"name":"Microtubule-associated proteins (MAPs)",
					"children":[
					{
						"name":"VDAG_10296 hypothetical protein\tK16732 PRC1; Ase1\/PRC1\/MAP65 family protein"
					}
					]
				},
				{
					"name":"Tubulin modification proteins",
					"children":[
					{
						"name":"Tubulin polyglutamylases"
					},
					{
						"name":"Tubulin polyglutamylase complex components"
					},
					{
						"name":"Other tubulin modification proteins",
						"children":[
						{
							"name":"VDAG_07271 TTL domain-containing protein\tK06047 TTL; tubulin---tyrosine ligase [EC:6.3.2.25]"
						},
						{
							"name":"VDAG_10040 TTL domain-containing protein\tK06047 TTL; tubulin---tyrosine ligase [EC:6.3.2.25]"
						}
						]
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"VDAG_03928 hypothetical protein\tK18633 MZT1; mitotic-spindle organizing protein 1"
					},
					{
						"name":"VDAG_06830 MEMO1 protein\tK06990 MEMO1; MEMO1 family protein"
					},
					{
						"name":"VDAG_08701 hypothetical protein\tK17292 TBCA; tubulin-specific chaperone A"
					},
					{
						"name":"VDAG_06777 cell polarity protein alp11\tK17262 TBCB; tubulin-specific chaperone B"
					},
					{
						"name":"VDAG_00852 tubulin-specific chaperone C\tK21766 TBCC; tubulin-specific chaperone C"
					},
					{
						"name":"VDAG_00688 small nuclear ribonucleoprotein\tK21767 TBCD; tubulin-specific chaperone D"
					},
					{
						"name":"VDAG_03226 tubulin-specific chaperone E\tK21768 TBCE; tubulin-specific chaperone E"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Septins",
			"children":[
			{
				"name":"Septins",
				"children":[
				{
					"name":"Group 1",
					"children":[
					{
						"name":"VDAG_07169 cell division control protein\tK16938 SEPT3_9_12; septin 3\/9\/12"
					}
					]
				},
				{
					"name":"Group 2",
					"children":[
					{
						"name":"VDAG_00736 cell division control protein\tK16944 SEPT7; septin 7"
					}
					]
				},
				{
					"name":"Group 3",
					"children":[
					{
						"name":"VDAG_04382 cell division control protein\tK16945 CDC11; cell division control protein 11"
					}
					]
				},
				{
					"name":"Group 4",
					"children":[
					{
						"name":"VDAG_01474 cell division control protein\tK16948 CDC12; cell division control protein 12"
					}
					]
				}
				]
			},
			{
				"name":"Septin associated proteins",
				"children":[
				{
					"name":"VDAG_01775 BR serine\/threonine-protein kinase\tK02515 HSL1; serine\/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]"
				},
				{
					"name":"VDAG_06319 MIZ zinc finger protein\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin homologs",
			"children":[
			{
				"name":"Actins"
			},
			{
				"name":"Actin-binding proteins"
			}
			]
		},
		{
			"name":"Intermediate filaments homologs"
		},
		{
			"name":"Microtubules homologs"
		},
		{
			"name":"MinD \/ ParA class of bacterial cytoskeletal proteins"
		}
		]
	}
	]
}