{
	"name":"vfi03110",
	"children":[
	{
		"name":"Heat shock proteins",
		"children":[
		{
			"name":"HSP110"
		},
		{
			"name":"HSP100",
			"children":[
			{
				"name":"VF_1765 clpA; ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity\tK03694 clpA; ATP-dependent Clp protease ATP-binding subunit ClpA"
			},
			{
				"name":"VF_0566 clpB; protein disaggregation chaperone\tK03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB"
			},
			{
				"name":"VF_0797 clpX; ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease\tK03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX"
			},
			{
				"name":"VF_2278 hslU; molecular chaperone and ATPase component of HslUV protease\tK03667 hslU; ATP-dependent HslUV protease ATP-binding subunit HslU"
			}
			]
		},
		{
			"name":"HSP90",
			"children":[
			{
				"name":"VF_0792 htpG; molecular chaperone HSP90 family\tK04079 HSP90A; molecular chaperone HtpG"
			}
			]
		},
		{
			"name":"HSP70 \/ DNAK",
			"children":[
			{
				"name":"VF_1467 chaperone, DnaK-like protein\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"VF_1994 dnaK; chaperone Hsp70\/DnaK, co-chaperone with DnaJ\tK04043 dnaK; molecular chaperone DnaK"
			},
			{
				"name":"VF_0621 hscA; DnaK-like molecular chaperone specific for Fe-S scaffold IscU\tK04044 hscA; molecular chaperone HscA"
			},
			{
				"name":"VF_1207 yegD; predicted chaperone\tK04046 yegD; hypothetical chaperone protein"
			}
			]
		},
		{
			"name":"HSP60 \/ Chaperonin",
			"children":[
			{
				"name":"VF_0205 groL; Cpn60 chaperonin GroEL, large subunit of GroESL\tK04077 groEL; chaperonin GroEL [EC:5.6.1.7]"
			}
			]
		},
		{
			"name":"HSP47"
		},
		{
			"name":"HSP40 \/ DNAJ",
			"children":[
			{
				"name":"VF_1108 chaperone protein DnaJ-like protein\tK03686 dnaJ; molecular chaperone DnaJ"
			},
			{
				"name":"VF_1993 dnaJ; chaperone Hsp40\/DnaJ, co-chaperone with DnaK\tK03686 dnaJ; molecular chaperone DnaJ"
			},
			{
				"name":"VF_0290 djlA; DnaJ-like protein, membrane anchored\tK05801 djlA; DnaJ like chaperone protein"
			},
			{
				"name":"VF_0620 hscB; DnaJ-like molecular chaperone specific for Fe-S scaffold IscU\tK04082 hscB; molecular chaperone HscB"
			}
			]
		},
		{
			"name":"HSP33",
			"children":[
			{
				"name":"VF_2477 hslO; heat shock and oxidative stress chaperone Hsp33\tK04083 hslO; molecular chaperone Hsp33"
			}
			]
		},
		{
			"name":"HSP24",
			"children":[
			{
				"name":"VF_1996 grpE; heat shock protein\tK03687 GRPE; molecular chaperone GrpE"
			}
			]
		},
		{
			"name":"HSP20",
			"children":[
			{
				"name":"VF_0013 ibpA; heat shock chaperone\tK04080 ibpA; molecular chaperone IbpA"
			},
			{
				"name":"VF_1466 small heat shock protein\tK04080 ibpA; molecular chaperone IbpA"
			}
			]
		},
		{
			"name":"HSP15",
			"children":[
			{
				"name":"VF_2476 hslR; ribosome-associated heat shock protein Hsp15\tK04762 hslR; ribosome-associated heat shock protein Hsp15"
			}
			]
		},
		{
			"name":"HSP10",
			"children":[
			{
				"name":"VF_0204 groS; Cpn10 chaperonin GroES, small subunit of GroESL\tK04078 groES; chaperonin GroES"
			}
			]
		},
		{
			"name":"GimC"
		}
		]
	},
	{
		"name":"Other chaperones and cochaperones",
		"children":[
		{
			"name":"Calnexin \/ calreticulin"
		},
		{
			"name":"DegP \/ HtrA",
			"children":[
			{
				"name":"VF_2225 degP; serine endoprotease DegP (protease Do), periplasmic\tK04771 degP; serine protease Do [EC:3.4.21.107]"
			}
			]
		},
		{
			"name":"AAA proteases",
			"children":[
			{
				"name":"VF_0479 hflB; ATP-dependent zinc-metalloprotease\tK03798 ftsH; cell division protease FtsH [EC:3.4.24.-]"
			}
			]
		},
		{
			"name":"PapD",
			"children":[
			{
				"name":"VF_2570 atpB; ATP synthase F0, A subunit\tK02108 ATPF0A; F-type H+-transporting ATPase subunit a"
			}
			]
		},
		{
			"name":"SecB",
			"children":[
			{
				"name":"VF_2349 secB; protein export chaperone\tK03071 secB; preprotein translocase subunit SecB"
			}
			]
		},
		{
			"name":"Sti1 \/ p60"
		},
		{
			"name":"Cdc37 \/ p50"
		},
		{
			"name":"BAG"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"VF_2342 cpxP; periplasmic protein CpxP, modulator of CpxAR signaling\tK06006 cpxP; periplasmic protein CpxP\/Spy"
			},
			{
				"name":"VF_A0818 conserved protein\tK09796 pccA; periplasmic copper chaperone A"
			},
			{
				"name":"VF_1571 torD; chaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I\tK03533 torD; TorA specific chaperone"
			},
			{
				"name":"VF_A0083 dmsD; twin-argninine leader-binding protein for DmsA and TorA\tK23349 dmsD; putative dimethyl sulfoxide reductase chaperone"
			}
			]
		}
		]
	},
	{
		"name":"Intramolecular chaperones",
		"children":[
		{
			"name":"Subtilisin family"
		},
		{
			"name":"Papain family"
		},
		{
			"name":"Other peptidases"
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"VF_0037 beta-N-acetylhexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"VF_2146 beta-hexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			},
			{
				"name":"VF_A1010 beta-hexosaminidase\tK12373 HEXA_B; hexosaminidase [EC:3.2.1.52]"
			}
			]
		}
		]
	},
	{
		"name":"Protein folding catalysts",
		"children":[
		{
			"name":"Peptidyl prolyl isomerase",
			"children":[
			{
				"name":"Cyclophilin",
				"children":[
				{
					"name":"VF_0721 peptidyl-prolyl cis-trans isomerase\tK03767 PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]"
				},
				{
					"name":"VF_1098 peptidyl-prolyl cis-trans isomerase\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"VF_1601 ppiB; peptidyl-prolyl cis-trans isomerase B (rotamase B)\tK03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]"
				},
				{
					"name":"VF_0800 ppiD; peptidyl-prolyl cis-trans isomerase (rotamase D)\tK03770 ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"FKBP",
				"children":[
				{
					"name":"VF_0226 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)\tK03772 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]"
				},
				{
					"name":"VF_0314 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)\tK03773 fklB; FKBP-type peptidyl-prolyl cis-trans isomerase FklB [EC:5.2.1.8]"
				},
				{
					"name":"VF_0469 fkpB; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase)\tK03774 slpA; FKBP-type peptidyl-prolyl cis-trans isomerase SlpA [EC:5.2.1.8]"
				},
				{
					"name":"VF_0223 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase)\tK03775 slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]"
				}
				]
			},
			{
				"name":"Parvulin",
				"children":[
				{
					"name":"VF_A0697 ppiC; peptidyl-prolyl cis-trans isomerase C (rotamase C)\tK03769 ppiC; peptidyl-prolyl cis-trans isomerase C [EC:5.2.1.8]"
				},
				{
					"name":"VF_0288 surA; peptidyl-prolyl cis-trans isomerase (PPIase)\tK03771 surA; peptidyl-prolyl cis-trans isomerase SurA [EC:5.2.1.8]"
				}
				]
			}
			]
		},
		{
			"name":"Protein disulfide isomerase",
			"children":[
			{
				"name":"VF_0057 trxA; thioredoxin\tK03671 TXN; thioredoxin"
			},
			{
				"name":"VF_0909 trxC; thioredoxin 2\tK03672 trxC; thioredoxin 2 [EC:1.8.1.8]"
			},
			{
				"name":"VF_0783 ybbN; predicted thioredoxin domain-containing protein\tK05838 ybbN; putative thioredoxin"
			},
			{
				"name":"VF_0890 grxA; glutaredoxin 1, redox coenzyme for ribonucleotide reductase (RNR1a)\tK03674 grxA; glutaredoxin 1"
			},
			{
				"name":"VF_1584 grxB; glutaredoxin 2 (Grx2)\tK03675 grxB; glutaredoxin 2"
			},
			{
				"name":"VF_1496 glutaredoxin\tK03676 grxC; glutaredoxin 3"
			},
			{
				"name":"VF_0922 grxD; glutaredoxin 4\tK07390 grxD; monothiol glutaredoxin"
			},
			{
				"name":"VF_0646 periplasmic protein disulfide isomerase, DsbA-like protein\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]"
			},
			{
				"name":"VF_2553 dsbA; periplasmic protein disulfide isomerase I\tK03673 dsbA; protein dithiol oxidoreductase (disulfide-forming) [EC:1.8.4.15]"
			},
			{
				"name":"VF_1635 dsbB; oxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I\tK03611 dsbB; protein dithiol:quinone oxidoreductase [EC:1.8.5.9]"
			},
			{
				"name":"VF_0449 dsbC; protein disulfide isomerase II\tK03981 dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]"
			},
			{
				"name":"VF_2356 dipZ; fused thiol:disulfide interchange protein: activator of DsbC\/conserved protein\tK04084 dsbD; thioredoxin:protein disulfide reductase [EC:1.8.4.16]"
			},
			{
				"name":"VF_1549 thiol:disulfide interchange protein TlpA\tK02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE"
			},
			{
				"name":"VF_1818 ccmG; periplasmic thioredoxin of cytochrome c-type biogenesis\tK02199 ccmG; cytochrome c biogenesis protein CcmG, thiol:disulfide interchange protein DsbE"
			}
			]
		}
		]
	}
	]
}