{
	"name":"vvp03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"112928803 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"112910483 ALKBH2; DNA oxidative demethylase ALKBH2 isoform X1\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"112914443 ALKBH3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"112923182 ASCC3; activating signal cointegrator 1 complex subunit 3 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"112910498 UNG; LOW QUALITY PROTEIN: uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"112935129 CCNO; cyclin-O\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"112930670 TDG; G\/T mismatch-specific thymine DNA glycosylase\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"112909135 MPG; DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"112911277 SMUG1; single-strand selective monofunctional uracil DNA glycosylase\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"112914785 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"112933691 MBD4; methyl-CpG-binding domain protein 4 isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"112933671 OGG1; N-glycosylase\/DNA lyase isoform X1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"112910111 NEIL1; endonuclease 8-like 1 isoform X1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"112926756 NEIL2; endonuclease 8-like 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"112932862 NEIL3; endonuclease 8-like 3\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"112909095 NTHL1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"112914843 APEX1; DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"112912374 APEX2; DNA-(apurinic or apyrimidinic site) lyase 2 isoform X1\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"112931281 POLD1; DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"112911682 POLD2; DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"112928649 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"112924189 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"112911600 POLE; DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"112921459 POLE2; DNA polymerase epsilon subunit 2\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"112923084 POLE3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"112916699 POLE4; DNA polymerase epsilon subunit 4\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"112930067 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"112931262 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"112916158 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"112931248 XRCC1; DNA repair protein XRCC1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"112917995 LIG3; DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"112930197 TDP1; tyrosyl-DNA phosphodiesterase 1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"112927557 APTX; aprataxin isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"112934404 APLF; aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"112931452 PNKP; bifunctional polynucleotide phosphatase\/kinase\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"112918651 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"112925668 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"112915159 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"112923556 PARP1; poly [ADP-ribose] polymerase 1 isoform X1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"112914982 PARP2; poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"112910742 PARP3; poly [ADP-ribose] polymerase 3\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"112918584 PARP4; poly [ADP-ribose] polymerase 4 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"112914451 XPC; DNA repair protein complementing XP-C cells isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"112908091 RAD23A; UV excision repair protein RAD23 homolog A isoform X1\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"112922975 RAD23B; UV excision repair protein RAD23 homolog B\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"112912370 centrin-2\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"112934005 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"112927492 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"112934425 CUL4B; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"112911054 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"112924073 DDB2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"112924841 POLR2A; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"112923701 POLR2B; DNA-directed RNA polymerase II subunit RPB2 isoform X1\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"112912793 DNA-directed RNA polymerase II subunit RPB3-like\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"112929650 POLR2C; DNA-directed RNA polymerase II subunit RPB3\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"112932713 POLR2D; DNA-directed RNA polymerase II subunit RPB4\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"112935475 POLR2E; DNA-directed RNA polymerases I, II, and III subunit RPABC1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"112929126 POLR2F; DNA-directed RNA polymerases I, II, and III subunit RPABC2\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"112924357 POLR2G; DNA-directed RNA polymerase II subunit RPB7 isoform X1\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"112926268 POLR2H; DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"112928543 POLR2I; DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"112923954 POLR2L; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"112935797 POLR2J; DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"112916960 POLR2K; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"112934005 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"112927492 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
						},
						{
							"name":"112934425 CUL4B; cullin-4B isoform X1\tK10609 CUL4; cullin 4"
						},
						{
							"name":"112911054 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"112935354 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"112913160 ERCC6; DNA excision repair protein ERCC-6 isoform X1\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"112920094 UVSSA; UV-stimulated scaffold protein A isoform X1\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"112908142 ELOF1; transcription elongation factor 1 homolog isoform X1\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"112932697 ERCC3; general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"112931257 ERCC2; general transcription and DNA repair factor IIH helicase subunit XPD isoform X1\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"112911569 GTF2H1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"112906917 general transcription factor IIH subunit 2\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"112933823 GTF2H3; general transcription factor IIH subunit 3 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"112913577 GTF2H4; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"112935134 GTF2H5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"112935878 CDK7; cyclin-dependent kinase 7 isoform X3\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"112915512 CCNH; LOW QUALITY PROTEIN: cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"112921362 MNAT1; CDK-activating kinase assembly factor MAT1\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112933167 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"112931729 RPA2; replication protein A 32 kDa subunit isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112923925 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"112910227 RPA4; LOW QUALITY PROTEIN: replication protein A 30 kDa subunit\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"112930889 XPA; DNA repair protein complementing XP-A cells isoform X1\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"112931206 ERCC1; DNA excision repair protein ERCC-1 isoform X1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"112923338 ERCC4; DNA repair endonuclease XPF isoform X1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"112927479 ERCC5; DNA repair protein complementing XP-G cells isoform X1\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"112931262 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"112914369 MMS19; MMS19 nucleotide excision repair protein homolog isoform X1\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"112906912 CCDC117; coiled-coil domain-containing protein 117\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"112916618 CIAO1; probable cytosolic iron-sulfur protein assembly protein CIAO1\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"112924368 CIAO2A; MIP18 family protein FAM96A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"112929397 CIAO2B; mitotic spindle-associated MMXD complex subunit MIP18\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"112925537 CUL3; cullin-3 isoform X1\tK03869 CUL3; cullin 3"
					},
					{
						"name":"112925956 CUL5; LOW QUALITY PROTEIN: cullin-5\tK10612 CUL5; cullin 5"
					},
					{
						"name":"112930296 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"112908995 ELOB; elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"112930145 ELOA; elongin-A\tK15076 ELOA; elongin-A"
					},
					{
						"name":"112918880 UBAP2L; ubiquitin-associated protein 2-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"112927547 UBAP2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"112915229 MSH2; DNA mismatch repair protein Msh2 isoform X1\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"112919583 MSH3; DNA mismatch repair protein Msh3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"112915230 MSH6; DNA mismatch repair protein Msh6\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"112922936 PMS1; PMS1 protein homolog 1 isoform X1\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"112921667 MLH1; DNA mismatch repair protein Mlh1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"112909998 PMS2; mismatch repair endonuclease PMS2 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"112927286 MLH3; DNA mismatch repair protein Mlh3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"112931281 POLD1; DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"112911682 POLD2; DNA polymerase delta subunit 2\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"112928649 POLD3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"112924189 POLD4; DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112933167 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"112931729 RPA2; replication protein A 32 kDa subunit isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112923925 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"112910227 RPA4; LOW QUALITY PROTEIN: replication protein A 30 kDa subunit\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"112919329 RFC1; replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"112926297 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"112935749 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"112918670 RFC3; replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"112926201 LOW QUALITY PROTEIN: replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"112932911 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"112930067 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"112923521 EXO1; exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"112918651 HMGB1; high mobility group protein B1\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"112925668 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"112931262 LIG1; DNA ligase 1 isoform X1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"112920011 WDR76; WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"112915765 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"112917079 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"112930896 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112922456 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112919685 ABRAXAS1; BRCA1-A complex subunit Abraxas 1 isoform X1\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"112925695 UIMC1; BRCA1-A complex subunit RAP80 isoform X1\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"112913116 BABAM1; BRISC and BRCA1-A complex member 1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"112933000 BABAM2; BRISC and BRCA1-A complex member 2 isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"112908355 LOW QUALITY PROTEIN: lys-63-specific deubiquitinase BRCC36-like\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					},
					{
						"name":"112918166 BRCC3; lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112917947 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"112932500 TOPBP1; DNA topoisomerase 2-binding protein 1 isoform X1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112925728 RBBP8; DNA endonuclease RBBP8\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"112915765 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"112917079 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"112930896 NBN; nibrin isoform X1\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112918664 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"112908291 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"112919949 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"112919949 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"112927197 RAD51B; DNA repair protein RAD51 homolog 2 isoform X1\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"112917927 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"112917992 RAD51D; DNA repair protein RAD51 homolog 4 isoform X1\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"112916196 XRCC2; DNA repair protein XRCC2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"112930297 XRCC3; DNA repair protein XRCC3\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"112917413 RAD52; DNA repair protein RAD52 homolog\tK10873 RAD52; DNA repair and recombination protein RAD52"
					},
					{
						"name":"112912513 LOW QUALITY PROTEIN: RAD52 motif-containing protein 1-like\tK10874 RDM1; RAD52 motif-containing protein 1"
					},
					{
						"name":"112912685 RDM1; LOW QUALITY PROTEIN: RAD52 motif-containing protein 1\tK10874 RDM1; RAD52 motif-containing protein 1"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"112914769 RAD54L; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"112910820 RAD54L2; helicase ARIP4\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"112931140 RAD54B; DNA repair and recombination protein RAD54B isoform X1\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"112917227 RECQL; ATP-dependent DNA helicase Q1 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"112916106 WRN; Werner syndrome ATP-dependent helicase\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"112921453 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"112911115 RECQL4; ATP-dependent DNA helicase Q4\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"112920796 RECQL5; ATP-dependent DNA helicase Q5 isoform X1\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"112921453 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"112907457 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"112924950 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"112911629 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"112933167 RPA1; replication protein A 70 kDa DNA-binding subunit\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"112931729 RPA2; replication protein A 32 kDa subunit isoform X1\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"112923925 RPA3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"112910227 RPA4; LOW QUALITY PROTEIN: replication protein A 30 kDa subunit\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"112929205 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit isoform X1\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"112925286 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"112932177 serine\/threonine-protein phosphatase 4 regulatory subunit 1-like isoform X1\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"112909042 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"112907319 PPP4R3A; serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"112915262 PPP4R3B; serine\/threonine-protein phosphatase 4 regulatory subunit 3B isoform X1\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"112919034 serine\/threonine-protein phosphatase 4 regulatory subunit 3B-like\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"112907325 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X1\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"112924251 AP5B1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"112921398 AP5M1; AP-5 complex subunit mu-1\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"112930080 AP5S1; AP-5 complex subunit sigma-1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"112929318 AP5Z1; AP-5 complex subunit zeta-1 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"112922115 SMC5; structural maintenance of chromosomes protein 5 isoform X1\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"112932098 SMC6; structural maintenance of chromosomes protein 6\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"112910730 FAM84A; protein FAM84A\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"112929178 NSMCE1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"112915976 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X1\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"112922401 NSMCE3; non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"112915176 NSMCE4A; non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"112916988 LOW QUALITY PROTEIN: non-structural maintenance of chromosomes element 4 homolog A-like\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"112929035 EID3; EP300-interacting inhibitor of differentiation 3\tK22826 EID3; EP300-interacting inhibitor of differentiation 3"
					},
					{
						"name":"112915488 SLF1; SMC5-SMC6 complex localization factor protein 1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"112914918 SLF2; SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"112927963 SIMC1; SUMO-interacting motif-containing protein 1\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"112917857 EME1; crossover junction endonuclease EME1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"112909014 EME2; LOW QUALITY PROTEIN: probable crossover junction endonuclease EME2\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"112927208 EXD2; exonuclease 3'-5' domain-containing protein 2 isoform X1\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"112924243 MUS81; crossover junction endonuclease MUS81 isoform X1\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"112927817 SWI5; DNA repair protein SWI5 homolog\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"112915799 SFR1; swi5-dependent recombination DNA repair protein 1 homolog isoform X1\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"112929339 SLX1A; structure-specific endonuclease subunit SLX1\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"112923260 SLX4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"112932118 GEN1; flap endonuclease GEN homolog 1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"112920022 SPG11; spatacsin\tK19026 SPG11; spatacsin"
					},
					{
						"name":"112927196 ZFYVE26; zinc finger FYVE domain-containing protein 26\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"112917375 RAD51AP1; RAD51-associated protein 1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"112914595 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"112922772 MORF4L1; mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"112928180 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"112925827 FIGNL1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"112910702 SPIDR; DNA repair-scaffolding protein isoform X1\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"112915978 FAM84B; protein FAM84B\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"112929311 BRAT1; BRCA1-associated ATM activator 1 isoform X1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"112909531 CFAP410; protein C21orf2 isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"112935624 HDGFL2; hepatoma-derived growth factor-related protein 2\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"112908153 SWSAP1; ATPase SWSAP1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"112928631 EMSY; BRCA2-interacting transcriptional repressor EMSY isoform X1\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"112909522 HSF2BP; heat shock factor 2-binding protein\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"112923169 MMS22L; protein MMS22-like\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"112911171 TONSL; tonsoku-like protein\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"112922566 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"112930723 PARPBP; PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"112910675 CUNH17orf53; uncharacterized protein C17orf53 homolog\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"112930059 MCM8; DNA helicase MCM8\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"112922758 MCM9; DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"112928353 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X1\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"112924359 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"112932445 MRNIP; MRN complex-interacting protein isoform X1\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"112932003 CUNHXorf57; RPA-related protein RADX isoform X1\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"112911241 RBM6; RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"112934010 XRCC6; LOW QUALITY PROTEIN: X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"112922451 XRCC5; X-ray repair cross-complementing protein 5\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"112929152 PRKDC; DNA-dependent protein kinase catalytic subunit isoform X1\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"112915765 MRE11; double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"112917079 RAD50; DNA repair protein RAD50 isoform X1\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"112927468 LIG4; DNA ligase 4 isoform X1\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"112915517 XRCC4; DNA repair protein XRCC4 isoform X1\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"112922536 NHEJ1; non-homologous end-joining factor 1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"112915159 POLL; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"112911693 POLM; DNA-directed DNA\/RNA polymerase mu isoform X1\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"112917661 DNTT; DNA nucleotidylexotransferase isoform X1\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"112916158 POLB; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"112927557 APTX; aprataxin isoform X1\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"112934404 APLF; aprataxin and PNK-like factor\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"112933106 DCLRE1C; protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"112920496 TDP2; tyrosyl-DNA phosphodiesterase 2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"112925259 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"112911484 PWWP domain-containing protein MUM1L1-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112912659 LOW QUALITY PROTEIN: PWWP domain-containing protein MUM1L1-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112912723 PWWP domain-containing protein MUM1L1-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112932013 MUM1L1; PWWP domain-containing protein MUM1L1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112935495 PWWP domain-containing protein MUM1 isoform X1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"112906905 PAXX; protein PAXX\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"112908892 CYREN; cell cycle regulator of non-homologous end joining isoform X1\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"112909022 JMJD8; jmjC domain-containing protein 8\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"112930028 SHLD1; shieldin complex subunit 1\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"112925269 SHLD2; shieldin complex subunit 2 isoform X1\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"112935675 shieldin complex subunit 3\tK26130 SHLD3; shieldin complex subunit 3"
					},
					{
						"name":"112909880 BEND4; BEN domain-containing protein 4\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"112917354 IFFO1; intermediate filament family orphan 1 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"112929807 IFFO2; intermediate filament family orphan 2\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"112924641 Fanconi anemia group A protein-like isoform X1\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"112910548 FANCB; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"112908709 FANCC; Fanconi anemia group C protein\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"112913924 FANCE; Fanconi anemia group E protein\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"112930868 FANCG; Fanconi anemia group G protein\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"112915267 FANCL; E3 ubiquitin-protein ligase FANCL\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"112921475 FANCM; Fanconi anemia group M protein\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"112928449 FAAP24; Fanconi anemia core complex-associated protein 24 isoform X1\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"112920678 FAAP100; Fanconi anemia core complex-associated protein 100\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"112925420 HES1; transcription factor HES-1\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"112929732 centromere protein S-like isoform X1\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"112920910 CENPX; centromere protein X isoform X1\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"112934543 UBE2T; ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"112921453 BLM; Bloom syndrome protein\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"112907457 TOP3B; DNA topoisomerase 3-beta-1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"112924950 TOP3A; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"112911629 RMI1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"112933672 FANCD2; Fanconi anemia group D2 protein\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"112921747 FANCI; Fanconi anemia group I protein\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"112910801 BRCA1; breast cancer type 1 susceptibility protein\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"112918664 BRCA2; breast cancer type 2 susceptibility protein\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"112917947 BRIP1; Fanconi anemia group J protein\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"112908291 PALB2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"112910162 FAN1; fanconi-associated nuclease 1 isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"112919949 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"112917927 RAD51C; DNA repair protein RAD51 homolog 3 isoform X1\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"112909072 TELO2; telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"112926075 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"112921643 WDR48; WD repeat-containing protein 48 isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"112927877 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"112909323 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"112935848 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2 isoform X1\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"112924163 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"112925618 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"112922905 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"112922385 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"112913950 RNF8; E3 ubiquitin-protein ligase RNF8\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"112913532 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"112928737 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"112907079 E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"112924854 WRAP53; telomerase Cajal body protein 1 isoform X1\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"112911430 TPRN; taperin\tK24164 TPRN; taperin"
					},
					{
						"name":"112935679 ZCWPW1; zinc finger CW-type PWWP domain protein 1 isoform X1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"112933503 WDR70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"112920011 WDR76; WD repeat-containing protein 76\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"112914469 HMCES; embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein isoform X1\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"112914023 POLH; DNA polymerase eta isoform X1\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"112919274 POLI; DNA polymerase iota isoform X1\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"112919752 POLK; DNA polymerase kappa isoform X1\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"112915161 REV1; DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"112925183 REV3L; DNA polymerase zeta catalytic subunit isoform X1\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"112920223 POLN; DNA polymerase nu\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"112910574 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"112917053 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"112933720 RAD18; E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"112932829 HLTF; helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"112919236 ubiquitin-conjugating enzyme E2 variant 1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"112926351 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"112929184 UBE2V2; ubiquitin-conjugating enzyme E2 variant 2 isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"112931948 UBE2V1; ubiquitin-conjugating enzyme E2 variant 1 isoform X1\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"112913808 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112914910 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112915544 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112917147 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112917600 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112917985 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112921655 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112928967 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112932306 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112932822 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				},
				{
					"name":"112932868 ubiquitin-conjugating enzyme E2 N-like\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"112930067 PCNA; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"112925494 PCLAF; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"112930723 PARPBP; PCNA-interacting partner\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"112927340 SPRTN; sprT-like domain-containing protein Spartan isoform X1\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"112907627 GCNA; acidic repeat-containing protein\tK26957 GCNA; germ cell nuclear acidic protein"
				},
				{
					"name":"112908418 developmental pluripotency-associated 5 protein-like\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				},
				{
					"name":"112926355 DPPA5; developmental pluripotency-associated 5 protein\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"112924186 RAD9A; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"112935251 RAD9B; cell cycle checkpoint control protein RAD9B\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"112911454 HUS1; checkpoint protein HUS1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"112908597 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"112906889 RAD17; cell cycle checkpoint protein RAD17 isoform X1\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"112926297 RFC4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"112935749 RFC2; replication factor C subunit 2 isoform X1\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"112918670 RFC3; replication factor C subunit 3 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"112926201 LOW QUALITY PROTEIN: replication factor C subunit 5-like\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"112932911 RFC5; replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"112908597 RAD1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"112922377 TIMELESS; protein timeless homolog isoform X1\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"112928657 TIPIN; TIMELESS-interacting protein isoform X1\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"112914686 CLSPN; claspin isoform X1\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"112909072 TELO2; telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"112928144 TTI1; TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"112916112 TTI2; TELO2-interacting protein 2\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"112913594 BAG6; large proline-rich protein BAG6 isoform X1\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"112911467 UBL4A; ubiquitin-like protein 4A\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"112929286 GET4; Golgi to ER traffic protein 4 homolog isoform X1\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"112918865 INTS3; integrator complex subunit 3 isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"112922387 NABP2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"112922916 NABP1; SOSS complex subunit B2 isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"112923065 INIP; SOSS complex subunit C\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"112934959 ATR; serine\/threonine-protein kinase ATR isoform X1\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"112912053 ATRIP; ATR-interacting protein isoform X1\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"112934371 ETAA1; ewing's tumor-associated antigen 1 isoform X1\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"112925961 ATM; serine-protein kinase ATM\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"112924853 TP53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"112920276 CHEK1; serine\/threonine-protein kinase Chk1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"112906959 CHEK2; serine\/threonine-protein kinase Chk2 isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"112912171 CDC25A; M-phase inducer phosphatase 1 isoform X1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"112930081 CDC25B; M-phase inducer phosphatase 2 isoform X1\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"112921903 CDC25C; LOW QUALITY PROTEIN: M-phase inducer phosphatase 3\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"112916971 YWHAZ; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"112920076 YWHAB; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"112927727 YWHAQ; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"112909830 YWHAH; 14-3-3 protein eta\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"112935798 YWHAG; 14-3-3 protein gamma\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"112933041 YWHAE; 14-3-3 protein epsilon isoform X1\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"112934712 NAV2; LOW QUALITY PROTEIN: neuron navigator 2\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"112907064 WEE2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"112927082 WEE1; wee1-like protein kinase isoform X1\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"112924868 PER1; period circadian protein homolog 1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"112908777 PER2; period circadian protein homolog 2 isoform X1\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"112924683 PER3; period circadian protein homolog 3 isoform X1\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"112913569 MDC1; mediator of DNA damage checkpoint protein 1 isoform X1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"112908438 PLS3; plastin-3 isoform X1\tK17336 PLS3; plastin-3"
				},
				{
					"name":"112921805 AEN; apoptosis-enhancing nuclease\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"112914964 PLK3; serine\/threonine-protein kinase PLK3\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"112935619 PLK5; inactive serine\/threonine-protein kinase PLK5\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"112910267 NEK4; serine\/threonine-protein kinase Nek4 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"112934153 NEK1; serine\/threonine-protein kinase Nek1 isoform X1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"112925580 NEK10; serine\/threonine-protein kinase Nek10 isoform X1\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"112932538 NEK11; serine\/threonine-protein kinase Nek11 isoform X1\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"112909288 DONSON; protein downstream neighbor of Son\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"112908070 KANK2; KN motif and ankyrin repeat domain-containing protein 2 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"112909691 KANK3; KN motif and ankyrin repeat domain-containing protein 3\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"112922131 KANK1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"112926077 KANK4; KN motif and ankyrin repeat domain-containing protein 4\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"112930618 CHMP4C; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"112919309 VPS4B; vacuolar protein sorting-associated protein 4B\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"112929525 VPS4A; vacuolar protein sorting-associated protein 4A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"112919951 ZFYVE19; abscission\/NoCut checkpoint regulator isoform X1\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"112923560 SDE2; replication stress response regulator SDE2 isoform X1\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"112916655 KRCC1; lysine-rich coiled-coil protein 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				},
				{
					"name":"112928170 BLCAP; bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"112913480 POLQ; DNA polymerase theta\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"112924765 MYBBP1A; myb-binding protein 1A\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"112934768 PRIMPOL; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"112912073 TREX1; three-prime repair exonuclease 1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"112911479 TREX2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"112916210 DCLRE1A; DNA cross-link repair 1A protein\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"112916758 DCLRE1B; 5' exonuclease Apollo\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"112908242 EXO5; exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"112920877 ENDOV; endonuclease V isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"112932593 ZRANB3; DNA annealing helicase and endonuclease ZRANB3\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"112913179 ANKLE1; LOW QUALITY PROTEIN: ankyrin repeat and LEM domain-containing protein 1\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"112919687 HELQ; helicase POLQ-like isoform X1\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"112908690 ERCC6L2; DNA excision repair protein ERCC-6-like 2\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"112911072 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"112914041 CDC5L; cell division cycle 5-like protein\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"112916764 BCAS2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"112933424 PLRG1; pleiotropic regulator 1 isoform X1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"112933922 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"112929306 NUDT1; 7,8-dihydro-8-oxoguanine triphosphatase\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"112926826 NUDT18; 8-oxo-dGDP phosphatase NUDT18 isoform X1\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"112920043 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"112928709 RRM1; ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"112916984 RRM2B; ribonucleoside-diphosphate reductase subunit M2 B isoform X1\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"112927720 RRM2; ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"112928803 MGMT; methylated-DNA--protein-cysteine methyltransferase\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"112910498 UNG; LOW QUALITY PROTEIN: uracil-DNA glycosylase\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"112911277 SMUG1; single-strand selective monofunctional uracil DNA glycosylase\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"112909135 MPG; DNA-3-methyladenine glycosylase isoform X1\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"112914785 MUTYH; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"112909095 NTHL1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"112907004 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"112907004 SSBP1; single-stranded DNA-binding protein, mitochondrial isoform X1\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"112933922 NUDT15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"112920043 DUT; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}