{
	"name":"zro04812",
	"children":[
	{
		"name":"Eukaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin filaments \/ Microfilaments",
			"children":[
			{
				"name":"Actins",
				"children":[
				{
					"name":"Actins",
					"children":[
					{
						"name":"ZYRO0F02772g actin\tK10355 ACTF; actin, other eukaryote"
					}
					]
				},
				{
					"name":"Actin-related proteins",
					"children":[
					{
						"name":"ZYRO0G05676g actin-related protein 1\tK16575 ACTR1; centractin"
					},
					{
						"name":"ZYRO0C01738g uncharacterized protein\tK11662 ACTR6; actin-related protein 6"
					}
					]
				}
				]
			},
			{
				"name":"Actin-binding proteins",
				"children":[
				{
					"name":"Myosins",
					"children":[
					{
						"name":"ZYRO0G19976g myosin 5\tK10356 MYO1; myosin I"
					},
					{
						"name":"ZYRO0D04158g myosin 2\tK10357 MYO5; myosin V"
					},
					{
						"name":"ZYRO0C11066g myosin 1\tK10352 MYH9s; myosin heavy chain 9\/10\/11\/14"
					}
					]
				},
				{
					"name":"Arp2\/3 complex",
					"children":[
					{
						"name":"ZYRO0C14762g uncharacterized protein\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
					},
					{
						"name":"ZYRO0D07942g uncharacterized protein\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
					},
					{
						"name":"ZYRO0B07502g uncharacterized protein\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
					},
					{
						"name":"ZYRO0E00660g uncharacterized protein\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
					},
					{
						"name":"ZYRO0C08426g uncharacterized protein\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
					},
					{
						"name":"ZYRO0B04928g actin-related protein 2\tK17260 ACTR2; actin-related protein 2"
					},
					{
						"name":"ZYRO0G01936g actin-related protein 3\tK18584 ACTR3; actin-related protein 3"
					}
					]
				},
				{
					"name":"WASP \/ WAVE",
					"children":[
					{
						"name":"ZYRO0D14586g actin-binding protein LAS17\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
					}
					]
				},
				{
					"name":"Formins"
				},
				{
					"name":"Profilin",
					"children":[
					{
						"name":"ZYRO0F10142g profilin\tK05759 PFN; profilin"
					}
					]
				},
				{
					"name":"Thymosin"
				},
				{
					"name":"ADF \/ Cofilin",
					"children":[
					{
						"name":"ZYRO0G07524g cofilin\tK05765 CFL; cofilin"
					},
					{
						"name":"SCMC complex"
					}
					]
				},
				{
					"name":"Gelsolin \/ villin"
				},
				{
					"name":"Ezrin\/Radixin\/Moesin"
				},
				{
					"name":"Capping proteins",
					"children":[
					{
						"name":"ZYRO0B01320g uncharacterized protein\tK10364 CAPZA; F-actin-capping protein subunit alpha"
					},
					{
						"name":"ZYRO0D16148g F-actin-capping protein subunit beta\tK10365 CAPZB; F-actin-capping protein subunit beta"
					}
					]
				},
				{
					"name":"Tropomyosins",
					"children":[
					{
						"name":"ZYRO0C15114g tropomyosin TPM1\tK17945 TPM1_2; tropomyosin, fungi type"
					}
					]
				},
				{
					"name":"Troponins"
				},
				{
					"name":"Cross-linking proteins",
					"children":[
					{
						"name":"ZYRO0B13838g uncharacterized protein\tK13886 CORO1B_1C_6; coronin-1B\/1C\/6"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"ZYRO0C00660g uncharacterized protein\tK20526 TAGLN; transgelin"
					},
					{
						"name":"ZYRO0E08030g uncharacterized protein\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
					},
					{
						"name":"ZYRO0D02860g glucose-induced degradation complex subunit FYV10\tK18624 MAEA; macrophage erythroblast attacher"
					},
					{
						"name":"ZYRO0D06512g fimbrin\tK17275 PLS1; plastin-1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Intermediate filaments",
			"children":[
			{
				"name":"Intermediate filaments",
				"children":[
				{
					"name":"Types I and II: Acidic and basic keratins"
				},
				{
					"name":"Type III"
				},
				{
					"name":"Type IV"
				},
				{
					"name":"Type V: Nuclear lamins"
				},
				{
					"name":"Type VI"
				},
				{
					"name":"Others"
				}
				]
			},
			{
				"name":"Intermediate filament-binding proteins"
			}
			]
		},
		{
			"name":"Microtubules",
			"children":[
			{
				"name":"Tubulins",
				"children":[
				{
					"name":"ZYRO0A00880g alpha-tubulin TUB3\tK07374 TUBA; tubulin alpha"
				},
				{
					"name":"ZYRO0F02860g beta-tubulin\tK07375 TUBB; tubulin beta"
				},
				{
					"name":"ZYRO0F11154g gamma-tubulin\tK10389 TUBG; tubulin gamma"
				}
				]
			},
			{
				"name":"Tubulin-binding proteins",
				"children":[
				{
					"name":"Kinesins",
					"children":[
					{
						"name":"ZYRO0E01078g uncharacterized protein\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
					},
					{
						"name":"ZYRO0B03234g uncharacterized protein\tK10398 KIF11; kinesin family member 11"
					},
					{
						"name":"ZYRO0C07898g kinesin motor protein CIN8\tK10398 KIF11; kinesin family member 11"
					},
					{
						"name":"ZYRO0E08668g tubulin-dependent ATPase KIP3\tK10401 KIF18A; kinesin family member 18A"
					},
					{
						"name":"ZYRO0B04290g uncharacterized protein\tK10405 KIFC1; kinesin family member C1 (minus-end-directed kinesin ATPase) [EC:5.6.1.4]"
					}
					]
				},
				{
					"name":"Stathmin"
				},
				{
					"name":"Microtubule severing proteins"
				},
				{
					"name":"EMAP"
				},
				{
					"name":"Dyneins",
					"children":[
					{
						"name":"ZYRO0D03168g dynein heavy chain\tK10413 DYNC1H; dynein cytoplasmic 1 heavy chain"
					},
					{
						"name":"ZYRO0B06424g dynein intermediate chain\tK10415 DYNC1I; dynein cytoplasmic 1 intermediate chain"
					},
					{
						"name":"ZYRO0D12672g dynein light chain\tK10418 DYNLL; dynein light chain LC8-type"
					},
					{
						"name":"Dynein-related proteins"
					}
					]
				},
				{
					"name":"Dynactins",
					"children":[
					{
						"name":"ZYRO0F11858g uncharacterized protein\tK04648 DCTN1; dynactin 1"
					},
					{
						"name":"ZYRO0D07370g uncharacterized protein\tK18599 JNM1; nuclear migration protein JNM1"
					},
					{
						"name":"ZYRO0G07546g uncharacterized protein\tK18600 LDB18; potein LDB18"
					}
					]
				},
				{
					"name":"Gamma-tubulin complex components",
					"children":[
					{
						"name":"ZYRO0C11792g uncharacterized protein\tK16569 TUBGCP2; gamma-tubulin complex component 2"
					},
					{
						"name":"ZYRO0G06358g uncharacterized protein\tK16570 TUBGCP3; gamma-tubulin complex component 3"
					}
					]
				},
				{
					"name":"XMAP215",
					"children":[
					{
						"name":"ZYRO0F01628g uncharacterized protein\tK24394 STU2; protein STU2"
					}
					]
				},
				{
					"name":"Cytoplasmic linker proteins (CLIPs)",
					"children":[
					{
						"name":"CLIP-associating proteins",
						"children":[
						{
							"name":"ZYRO0G13178g uncharacterized protein\tK16578 CLASP1_2; CLIP-associating protein 1\/2"
						}
						]
					}
					]
				},
				{
					"name":"Fused toes protein (FTS)"
				},
				{
					"name":"Hook proteins"
				},
				{
					"name":"FTS and Hook-interacting proteins (FHIP)"
				},
				{
					"name":"EB \/ APC",
					"children":[
					{
						"name":"ZYRO0D15268g microtubule-binding protein BIM1\tK10436 MAPRE; microtubule-associated protein, RP\/EB family"
					}
					]
				},
				{
					"name":"Microtubule-associated proteins (MAPs)",
					"children":[
					{
						"name":"ZYRO0B15928g uncharacterized protein\tK16732 PRC1; Ase1\/PRC1\/MAP65 family protein"
					}
					]
				},
				{
					"name":"Tubulin modification proteins",
					"children":[
					{
						"name":"Tubulin polyglutamylases"
					},
					{
						"name":"Tubulin polyglutamylase complex components"
					},
					{
						"name":"Other tubulin modification proteins",
						"children":[
						{
							"name":"ZYRO0C15796g uncharacterized protein\tK06047 TTL; tubulin---tyrosine ligase [EC:6.3.2.25]"
						}
						]
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"ZYRO0G12034g uncharacterized protein\tK06990 MEMO1; MEMO1 family protein"
					},
					{
						"name":"ZYRO0F12078g uncharacterized protein\tK17292 TBCA; tubulin-specific chaperone A"
					},
					{
						"name":"ZYRO0G05742g uncharacterized protein\tK17262 TBCB; tubulin-specific chaperone B"
					},
					{
						"name":"ZYRO0E08008g GTPase-activating protein CIN2\tK21766 TBCC; tubulin-specific chaperone C"
					},
					{
						"name":"ZYRO0D04708g uncharacterized protein\tK21767 TBCD; tubulin-specific chaperone D"
					},
					{
						"name":"ZYRO0D09614g uncharacterized protein\tK21768 TBCE; tubulin-specific chaperone E"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Septins",
			"children":[
			{
				"name":"Septins",
				"children":[
				{
					"name":"Group 1",
					"children":[
					{
						"name":"ZYRO0E04378g septin CDC10\tK16938 SEPT3_9_12; septin 3\/9\/12"
					}
					]
				},
				{
					"name":"Group 2",
					"children":[
					{
						"name":"ZYRO0B00770g septin CDC3\tK16944 SEPT7; septin 7"
					}
					]
				},
				{
					"name":"Group 3",
					"children":[
					{
						"name":"ZYRO0G02354g septin CDC11\tK16945 CDC11; cell division control protein 11"
					},
					{
						"name":"ZYRO0C10186g septin SHS1\tK16946 SHS1; seventh homolog of septin 1"
					},
					{
						"name":"ZYRO0A09482g septin SPR28\tK16947 SPR28; sporulation-regulated protein 28"
					}
					]
				},
				{
					"name":"Group 4",
					"children":[
					{
						"name":"ZYRO0A06270g septin CDC12\tK16948 CDC12; cell division control protein 12"
					},
					{
						"name":"ZYRO0B07810g septin SPR3\tK12773 SPR3; sporulation-regulated protein 3"
					}
					]
				}
				]
			},
			{
				"name":"Septin associated proteins",
				"children":[
				{
					"name":"ZYRO0C15268g uncharacterized protein\tK18637 AXL2; axial budding pattern protein 2"
				},
				{
					"name":"ZYRO0F15510g uncharacterized protein\tK18638 BNI4; protein BNI4"
				},
				{
					"name":"ZYRO0G03366g protein kinase HSL1\tK02515 HSL1; serine\/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]"
				},
				{
					"name":"ZYRO0F17402g serine\/threonine protein kinase\tK06668 GIN4; serine\/threonine-protein kinase GIN4 [EC:2.7.11.-]"
				},
				{
					"name":"ZYRO0D12078g SUMO ligase SIZ1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin homologs",
			"children":[
			{
				"name":"Actins"
			},
			{
				"name":"Actin-binding proteins"
			}
			]
		},
		{
			"name":"Intermediate filaments homologs"
		},
		{
			"name":"Microtubules homologs"
		},
		{
			"name":"MinD \/ ParA class of bacterial cytoskeletal proteins"
		}
		]
	}
	]
}