{
	"name":"br08402",
	"children":[
	{
		"name":"Carbohydrate metabolism",
		"children":[
		{
			"name":"nt06031  Citrate cycle and pyruvate metabolism",
			"children":[
			{
				"name":"H01225  D-2-hydroxyglutaric aciduria"
			},
			{
				"name":"H01096  Pyruvate kinase deficiency"
			},
			{
				"name":"H00072  Pyruvate dehydrogenase complex deficiency"
			},
			{
				"name":"H01997  Pyruvate dehydrogenase E1-alpha deficiency"
			},
			{
				"name":"H01998  Pyruvate dehydrogenase E1-beta deficiency"
			},
			{
				"name":"H01999  Pyruvate dehydrogenase E2 deficiency"
			},
			{
				"name":"H02000  Dihydrolipoamide dehydrogenase deficiency"
			},
			{
				"name":"H00073  Pyruvate carboxylase deficiency"
			},
			{
				"name":"H02520  Phosphoenolpyruvate carboxykinase deficiency"
			},
			{
				"name":"H01022  Diseases of the tricarboxylic acid cycle"
			},
			{
				"name":"H02004  Fumarase deficiency"
			},
			{
				"name":"H02006  Alpha-ketoglutarate dehydrogenase complex deficiency"
			},
			{
				"name":"H02113  Infantile cerebellar-retinal degeneration"
			},
			{
				"name":"H02562  Yoon-Bellen neurodevelopmental syndrome"
			},
			{
				"name":"H02005  Mitochondrial complex II deficiency"
			}
			]
		},
		{
			"name":"nt06017  Glycogen metabolism",
			"children":[
			{
				"name":"H00069  Glycogen storage disease"
			},
			{
				"name":"H01939  Glycogen storage disease type I"
			},
			{
				"name":"H01940  Glycogen storage disease type II"
			},
			{
				"name":"H01941  Glycogen storage disease type III"
			},
			{
				"name":"H01942  Glycogen storage disease type IV"
			},
			{
				"name":"H01943  Glycogen storage disease type V"
			},
			{
				"name":"H01944  Glycogen storage disease type VI"
			},
			{
				"name":"H01945  Glycogen storage disease type VII"
			},
			{
				"name":"H01946  Glycogen storage disease type XI"
			},
			{
				"name":"H01947  Fanconi-Bickel syndrome"
			},
			{
				"name":"H01949  Glycogen storage disease type 0b"
			},
			{
				"name":"H01950  Glycogen storage disease type 0a"
			},
			{
				"name":"H01951  Glycogen storage disease type X"
			},
			{
				"name":"H01952  Glycogen storage disease type XII"
			},
			{
				"name":"H01953  Glycogen storage disease type XIII"
			},
			{
				"name":"H01955  Glycogen storage disease type XV"
			}
			]
		},
		{
			"name":"nt06023  Galactose degradation",
			"children":[
			{
				"name":"H00070  Galactosemia"
			},
			{
				"name":"H02008  Galactose-1P uridylyltransferase deficiency"
			},
			{
				"name":"H02009  Galactokinase deficiency"
			},
			{
				"name":"H02010  Galactose epimerase deficiency"
			}
			]
		}
		]
	},
	{
		"name":"Lipid\/glycolipid metabolism",
		"children":[
		{
			"name":"nt06020  beta-Oxidation in mitochondria",
			"children":[
			{
				"name":"H01589  Systemic primary carnitine deficiency"
			},
			{
				"name":"H01981  Carnitine palmitoyltransferase I deficiency"
			},
			{
				"name":"H01982  Carnitine palmitoyltransferase II deficiency"
			},
			{
				"name":"H01983  Carnitine-acylcarnitine translocase deficiency"
			},
			{
				"name":"H00392  Very long-chain acyl-CoA dehydrogenase deficiency"
			},
			{
				"name":"H00488  MCAD deficiency"
			},
			{
				"name":"H00489  LCHAD deficiency"
			},
			{
				"name":"H00525  Disorders of mitochondrial fatty-acid oxidation"
			},
			{
				"name":"H01352  Mitochondrial trifunctional protein deficiency"
			},
			{
				"name":"H01364  3-Hydroxyacyl-CoA dehydrogenase deficiency"
			},
			{
				"name":"H01980  SCAD deficiency"
			}
			]
		},
		{
			"name":"nt06021  beta-Oxidation in peroxisome",
			"children":[
			{
				"name":"H02099  Alpha-methylacyl-CoA racemase deficiency"
			},
			{
				"name":"H00407  Peroxisomal beta-oxidation enzyme deficiency"
			},
			{
				"name":"H00874  Leukoencephalopathy with dystonia and motor neuropathy"
			},
			{
				"name":"H02096  Peroxisomal acyl-CoA oxidase deficiency"
			},
			{
				"name":"H02098  D-bifunctional protein deficiency"
			}
			]
		},
		{
			"name":"nt06034  Cholesterol biosynthesis",
			"children":[
			{
				"name":"H01143  Vitamin D-dependent rickets"
			},
			{
				"name":"H00161  Smith-Lemli-Opitz syndrome"
			},
			{
				"name":"H00206  Mevalonate kinase deficiency"
			},
			{
				"name":"H00617  Desmosterolosis"
			},
			{
				"name":"H01281  Lathosterolosis"
			},
			{
				"name":"H03060  Squalene synthase deficiency"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H01933  Porokeratosis"
			},
			{
				"name":"H02132  Microcephaly syndrome"
			},
			{
				"name":"H00447  HEM skeletal dysplasia"
			},
			{
				"name":"H00496  Congenital hemidysplasia with ichthyosiform nevus and limb defects (CHILD)"
			},
			{
				"name":"H01194  X-linked chondrodysplasia punctata"
			},
			{
				"name":"H02303  Alopecia-mental retardation syndrome"
			},
			{
				"name":"H01917  CK syndrome"
			},
			{
				"name":"H02248  MEND syndrome"
			}
			]
		},
		{
			"name":"nt06019  Steroid hormone biosynthesis",
			"children":[
			{
				"name":"H00216  Congenital adrenal hyperplasia"
			},
			{
				"name":"H01111  Cortisone reductase deficiency"
			},
			{
				"name":"H00259  Apparent mineralocorticoid excess syndrome"
			},
			{
				"name":"H00258  Aldosterone synthase deficiency"
			},
			{
				"name":"H02314  Adrenal insufficiency, congenital, with 46XY sex reversal, partial or complete"
			},
			{
				"name":"H01163  Corticosteroid-binding globulin (CBG) deficiency"
			},
			{
				"name":"H00794  Aromatase excess syndrome"
			},
			{
				"name":"H02020  Aromatase deficiency"
			},
			{
				"name":"H00607  46,XY gonadal dysgenesis"
			},
			{
				"name":"H00608  46,XY disorder of sex development due to testosterone secretion defect"
			}
			]
		},
		{
			"name":"nt06022  Bile acid biosynthesis",
			"children":[
			{
				"name":"H00151  Cerebrotendinous xanthomatosis"
			},
			{
				"name":"H00628  Congenital bile acid synthesis defect"
			}
			]
		},
		{
			"name":"nt06014  Sphingolipid degradation",
			"children":[
			{
				"name":"H00423  Sphingolipidosis"
			},
			{
				"name":"H00124  GM2 gangliosidoses"
			},
			{
				"name":"H00281  GM1 gangliosidosis"
			},
			{
				"name":"H02016  Tay-Sachs disease"
			},
			{
				"name":"H02017  Sandhoff disease"
			},
			{
				"name":"H00125  Fabry disease"
			},
			{
				"name":"H00127  Metachromatic leukodystrophy"
			},
			{
				"name":"H00126  Gaucher disease"
			},
			{
				"name":"H00137  Niemann-Pick disease type A\/B"
			},
			{
				"name":"H00138  Farber lipogranulomatosis"
			},
			{
				"name":"H00135  Krabbe disease"
			}
			]
		}
		]
	},
	{
		"name":"Nucleotide metabolism",
		"children":[
		{
			"name":"nt06027  Purine salvage pathway",
			"children":[
			{
				"name":"H00194  Lesch-Nyhan syndrome"
			},
			{
				"name":"H00195  Adenine phosphoribosyltransferase deficiency"
			}
			]
		}
		]
	},
	{
		"name":"Amino acid metabolism",
		"children":[
		{
			"name":"nt06033  Glycine, serine and arginine metabolism",
			"children":[
			{
				"name":"H01079  3-Phosphoglycerate dehydrogenase (3-PGDH) deficiency"
			},
			{
				"name":"H01082  Phosphoserine aminotransferase deficiency"
			},
			{
				"name":"H02116  Phosphoserine phosphatase deficiency"
			},
			{
				"name":"H01003  Dimethylglycine dehydrogenase deficiency"
			},
			{
				"name":"H00191  Nonketotic hyperglycinemia"
			},
			{
				"name":"H02657  Sarcosinemia"
			},
			{
				"name":"H00190  Hyperprolinemia"
			},
			{
				"name":"H00189  Ornithinaemia"
			},
			{
				"name":"H02919  Bachmann-Bupp syndrome"
			},
			{
				"name":"H01894  Multiple mitochondrial dysfunctions syndrome"
			},
			{
				"name":"H00849  Cerebral creatine deficiency syndrome"
			},
			{
				"name":"H02117  Neu-Laxova syndrome"
			},
			{
				"name":"H00597  Snyder-Robinson syndrome"
			},
			{
				"name":"H02918  Neurodevelopmental disorder with cardiomyopathy, spasticity, and brain abnormalities"
			}
			]
		},
		{
			"name":"nt06030  Methionine metabolism",
			"children":[
			{
				"name":"H00182  Cystathioninuria"
			},
			{
				"name":"H00183  Homocystinuria"
			},
			{
				"name":"H00184  Hypermethioninemia"
			}
			]
		},
		{
			"name":"nt06024  Valine, leucine and isoleucine degradation",
			"children":[
			{
				"name":"H00172  Maple syrup urine disease"
			},
			{
				"name":"H01279  Isobutyryl-CoA dehydrogenase deficiency"
			},
			{
				"name":"H02285  Methylmalonate semialdehyde dehydrogenase deficiency"
			},
			{
				"name":"H01349  Methacrylic aciduria"
			},
			{
				"name":"H00173  Isovaleric acidemia"
			},
			{
				"name":"H00174  Methylmalonic aciduria"
			},
			{
				"name":"H00175  Propionic acidemia"
			},
			{
				"name":"H00181  3-Methylcrotonylglycinuria"
			},
			{
				"name":"H00375  SBCAD deficiency"
			},
			{
				"name":"H00754  3-Methylglutaconic aciduria"
			},
			{
				"name":"H00925  2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency"
			},
			{
				"name":"H00179  3-Hydroxy-3-methylglutaryl-CoA lyase deficiency"
			},
			{
				"name":"H02000  Dihydrolipoamide dehydrogenase deficiency"
			}
			]
		},
		{
			"name":"nt06036  Lysine degradation",
			"children":[
			{
				"name":"H01583  Hydroxykynureninuria"
			},
			{
				"name":"H00188  Hyperlysinemia"
			},
			{
				"name":"H01242  Saccharopinuria"
			},
			{
				"name":"H02644  Alpha-aminoadipic and alpha-ketoadipic aciduria"
			},
			{
				"name":"H00178  Glutaric acidemia"
			},
			{
				"name":"H01929  2,4-Dienoyl-CoA reductase deficiency"
			},
			{
				"name":"H01247  Pyridoxine-dependent epilepsy"
			},
			{
				"name":"H02087  Vertebral, cardiac, renal, and limb defects syndrome"
			}
			]
		},
		{
			"name":"nt06010  Urea cycle",
			"children":[
			{
				"name":"H00187  Ornithine transcarbamylase deficiency"
			},
			{
				"name":"H01398  Primary hyperammonemia (Urea cycle disorders)"
			},
			{
				"name":"H01028  Argininosuccinic aciduria"
			},
			{
				"name":"H00164  Carbamoyl phosphate synthetase I deficiency"
			},
			{
				"name":"H00186  Hyperargininemia"
			},
			{
				"name":"H00185  Citrullinemia"
			},
			{
				"name":"H01032  N-acetylglutamate synthase deficiency"
			}
			]
		},
		{
			"name":"nt06037  Histidine metabolism",
			"children":[
			{
				"name":"H01262  Formiminotransferase deficiency"
			},
			{
				"name":"H00171  Histidinemia"
			},
			{
				"name":"H01233  Urocanase deficiency"
			},
			{
				"name":"H00862  Tourette syndrome"
			}
			]
		},
		{
			"name":"nt06016  Phenylalanine and tyrosine metabolism",
			"children":[
			{
				"name":"H00167  Phenylketonuria"
			},
			{
				"name":"H00163  Alkaptonuria"
			},
			{
				"name":"H00165  Tyrosinemia"
			}
			]
		},
		{
			"name":"nt06028  Dopamine and serotonin metabolism",
			"children":[
			{
				"name":"H01005  Dopamine beta-hydroxylase deficiency"
			},
			{
				"name":"H01161  Aromatic L-amino acid decarboxylase deficiency"
			},
			{
				"name":"H02597  Sepiapterin reductase deficiency"
			},
			{
				"name":"H00548  Brunner syndrome"
			},
			{
				"name":"H01895  Attention deficit hyperactivity disorder (ADHD)"
			},
			{
				"name":"H01646  Major depressive disorder"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H02557  Dopa-responsive dystonia"
			},
			{
				"name":"H02676  Infantile-onset parkinsonism-dystonia"
			},
			{
				"name":"H00168  Oculocutaneous albinism"
			}
			]
		},
		{
			"name":"nt06026  Glutathione biosynthesis",
			"children":[
			{
				"name":"H00668  Anemia due to disorders of glutathione metabolism"
			},
			{
				"name":"H02313  5-Oxoprolinase deficiency"
			},
			{
				"name":"H02312  Glutathione synthetase deficiency"
			},
			{
				"name":"H01375  Glucose 6-phosphate dehydrogenase deficiency"
			},
			{
				"name":"H01825  Spondylometaphyseal dysplasia, Sedaghatian type"
			}
			]
		}
		]
	},
	{
		"name":"Glycan\/glycoprotein metabolism",
		"children":[
		{
			"name":"nt06015  N-Glycan biosynthesis",
			"children":[
			{
				"name":"H00118  Congenital disorders of glycosylation type I"
			},
			{
				"name":"H00119  Congenital disorders of glycosylation type II"
			}
			]
		},
		{
			"name":"nt06013  O-Glycan biosynthesis",
			"children":[
			{
				"name":"H01959  Muscular dystrophy-dystroglycanopathy type C"
			},
			{
				"name":"H00120  Muscular dystrophy-dystroglycanopathy type A"
			},
			{
				"name":"H01960  Muscular dystrophy-dystroglycanopathy type B"
			},
			{
				"name":"H02307  Muscular dystrophy-dystroglycanopathy"
			}
			]
		},
		{
			"name":"nt06029  Glycosaminoglycan biosynthesis",
			"children":[
			{
				"name":"H02491  Immunoskeletal dysplasia with neurodevelopmental abnormalities"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H00762  Spondyloepiphyseal dysplasia with congenital joint dislocations"
			},
			{
				"name":"H00122  Multiple exostoses"
			},
			{
				"name":"H01494  SEMD with joint laxity type"
			},
			{
				"name":"H00494  Desbuquois syndrome"
			},
			{
				"name":"H01498  Multiple joint dislocations, short stature, craniofacial dysmorphism, and congenital heart defects"
			},
			{
				"name":"H01496  Spondyloocular syndrome"
			},
			{
				"name":"H02551  Skeletal dysplasia with joint laxity and advanced bone age"
			},
			{
				"name":"H01497  Temtamy preaxial brachydactyly syndrome"
			},
			{
				"name":"H02239  Ehlers-Danlos syndrome, spondylodysplastic type"
			},
			{
				"name":"H02246  Ehlers-Danlos syndrome musculocontractural type"
			}
			]
		},
		{
			"name":"nt06012  Glycosaminoglycan degradation",
			"children":[
			{
				"name":"H00421  Mucopolysaccharidosis"
			},
			{
				"name":"H00128  Mucopolysaccharidosis type I"
			},
			{
				"name":"H00129  Mucopolysaccharidosis type II"
			},
			{
				"name":"H00123  Mucopolysaccharidosis type IV"
			},
			{
				"name":"H00131  Mucopolysaccharidosis type VI"
			},
			{
				"name":"H00130  Mucopolysaccharidosis type III"
			},
			{
				"name":"H00132  Mucopolysaccharidosis type VII"
			},
			{
				"name":"H00133  Mucopolysaccharidosis type IX"
			}
			]
		},
		{
			"name":"nt06018  GPI-anchor biosynthesis",
			"children":[
			{
				"name":"H01486  Multiple congenital anomalies-hypotonia-seizures syndrome"
			},
			{
				"name":"H01487  CHIME syndrome"
			},
			{
				"name":"H01127  PIGM-congenital disorder of glycosylation"
			},
			{
				"name":"H01489  Inherited glycosylphosphatidylinositol deficiencies"
			},
			{
				"name":"H01485  Autosomal recessive mental retardation-42"
			},
			{
				"name":"H01488  Hyperphosphatasia with mental retardation syndrome"
			}
			]
		},
		{
			"name":"nt06035  Blood group carbohydrate antigen biosynthesis",
			"children":[
			{
				"name":"H00119  Congenital disorders of glycosylation type II"
			}
			]
		}
		]
	},
	{
		"name":"Cofactor\/vitamin metabolism",
		"children":[
		{
			"name":"nt06032  Lipoic acid metabolism",
			"children":[
			{
				"name":"H02000  Dihydrolipoamide dehydrogenase deficiency"
			},
			{
				"name":"H02438  Hyperglycinemia, lactic acidosis, and seizures"
			},
			{
				"name":"H02518  Neonatal severe encephalopathy with lactic acidosis and brain abnormalities"
			},
			{
				"name":"H02643  Lipoyltransferase 1 deficiency"
			}
			]
		},
		{
			"name":"nt06038  Folate metabolism",
			"children":[
			{
				"name":"H01197  Dihydrofolate reductase deficiency"
			},
			{
				"name":"H01262  Formiminotransferase deficiency"
			},
			{
				"name":"H01003  Dimethylglycine dehydrogenase deficiency"
			},
			{
				"name":"H02657  Sarcosinemia"
			},
			{
				"name":"H00262  Neural tube defects, folate-sensitive"
			}
			]
		},
		{
			"name":"nt06025  Molybdenum cofactor biosynthesis",
			"children":[
			{
				"name":"H02311  Molybdenum cofactor deficiency"
			},
			{
				"name":"H00192  Xanthinuria"
			}
			]
		},
		{
			"name":"nt06011  Heme biosynthesis",
			"children":[
			{
				"name":"H01763  Porphyria"
			}
			]
		},
		{
			"name":"nt06538  Cobalamin transport and metabolism",
			"children":[
			{
				"name":"H01277  Vitamin B12 deficiency anaemia"
			},
			{
				"name":"H01190  Transcobalamin II deficiency"
			},
			{
				"name":"H00183  Homocystinuria"
			},
			{
				"name":"H00174  Methylmalonic aciduria"
			},
			{
				"name":"H02221  Methylmalonic aciduria and homocystinuria"
			},
			{
				"name":"H02222  Methylmalonic acidemia and hyperhomocysteinemia, cblX type"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00262  Neural tube defects, folate-sensitive"
			}
			]
		}
		]
	},
	{
		"name":"Replication, repair and transcription",
		"children":[
		{
			"name":"nt06509  DNA replication",
			"children":[
			{
				"name":"H02569  Pulmonary fibrosis and\/or bone marrow failure, telomere-related"
			},
			{
				"name":"H02525  Disorders of innate immunity"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H00094  Immunodeficiency associated with DNA repair defects"
			},
			{
				"name":"H02014  Ataxia-telangiectasia-like syndrome"
			},
			{
				"name":"H02031  Inclusion body myopathy with Paget disease of bone and frontotemporal dementia"
			},
			{
				"name":"H00290  Aicardi-Goutieres syndrome"
			},
			{
				"name":"H02484  X-linked reticulate pigmentary disorder with systemic manifestations"
			},
			{
				"name":"H00658  X-linked syndromic intellectual developmental disorder"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H01118  Progressive external ophthalmoplegia"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00564  Primary ciliary dyskinesia"
			},
			{
				"name":"H02366  Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome"
			},
			{
				"name":"H02840  Morimoto-Ryu-Malicdan neuromuscular syndrome"
			},
			{
				"name":"H00992  Seckel syndrome"
			},
			{
				"name":"H01993  Baller-Gerold syndrome"
			},
			{
				"name":"H01889  Meier-Gorlin syndrome"
			},
			{
				"name":"H01734  Rothmund-Thomson syndrome"
			},
			{
				"name":"H00965  RAPADILINO syndrome"
			},
			{
				"name":"H02369  IMAGE-I syndrome"
			},
			{
				"name":"H02370  FILS syndrome"
			},
			{
				"name":"H02625  Primordial dwarfism-immunodeficiency-lipodystrophy syndrome"
			},
			{
				"name":"H01623  MDPL syndrome"
			}
			]
		},
		{
			"name":"nt06510  Telomere length regulation",
			"children":[
			{
				"name":"H00038  Melanoma"
			},
			{
				"name":"H02624  Tumor predisposition syndrome"
			},
			{
				"name":"H01132  Aplastic anemia"
			},
			{
				"name":"H00507  Dyskeratosis congenita"
			},
			{
				"name":"H02569  Pulmonary fibrosis and\/or bone marrow failure, telomere-related"
			},
			{
				"name":"H02580  Hereditary sensory neuropathy with spastic paraplegia"
			},
			{
				"name":"H02251  Cerebroretinal microangiopathy with calcifications and cysts"
			},
			{
				"name":"H02843  Brain malformations and seizures by impaired function of TRiC"
			}
			]
		},
		{
			"name":"nt06504  Base excision repair",
			"children":[
			{
				"name":"H00018  Gastric cancer"
			},
			{
				"name":"H02568  Polymerase proofreading-associated polyposis"
			},
			{
				"name":"H00021  Renal cell carcinoma"
			},
			{
				"name":"H01025  Familial adenomatous polyposis"
			},
			{
				"name":"H02624  Tumor predisposition syndrome"
			},
			{
				"name":"H00086  Immunodeficiency with hyper-IgM"
			},
			{
				"name":"H00091  T-B+Severe combined immunodeficiency"
			},
			{
				"name":"H00094  Immunodeficiency associated with DNA repair defects"
			},
			{
				"name":"H00469  Mitochondrial DNA depletion syndrome"
			},
			{
				"name":"H01390  Mitochondrial neurogastrointestinal encephalomyopathy"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H02573  Autosomal recessive spinocerebellar ataxias with axonal neuropathy"
			},
			{
				"name":"H00848  Ataxia with ocular apraxia"
			},
			{
				"name":"H02572  Neurodegeneration, childhood-onset, stress-induced, with variable ataxia and seizures"
			},
			{
				"name":"H01118  Progressive external ophthalmoplegia"
			},
			{
				"name":"H02366  Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome"
			},
			{
				"name":"H02369  IMAGE-I syndrome"
			},
			{
				"name":"H02370  FILS syndrome"
			},
			{
				"name":"H01623  MDPL syndrome"
			}
			]
		},
		{
			"name":"nt06502  Nucleotide excision repair",
			"children":[
			{
				"name":"H00238  Fanconi anemia"
			},
			{
				"name":"H02569  Pulmonary fibrosis and\/or bone marrow failure, telomere-related"
			},
			{
				"name":"H00091  T-B+Severe combined immunodeficiency"
			},
			{
				"name":"H00403  Disorders of nucleotide excision repair"
			},
			{
				"name":"H02014  Ataxia-telangiectasia-like syndrome"
			},
			{
				"name":"H02571  Neurodevelopmental disorder with hypotonia and variable intellectual and behavioral abnormalities"
			},
			{
				"name":"H00866  Trichothiodystrophy"
			},
			{
				"name":"H02131  UV-sensitive syndrome"
			},
			{
				"name":"H01428  Xeroderma pigmentosum"
			},
			{
				"name":"H00076  Cockayne syndrome"
			},
			{
				"name":"H02570  Cerebro-oculo-facio-skeletal syndrome"
			},
			{
				"name":"H02560  White-Kernohan syndrome"
			}
			]
		},
		{
			"name":"nt06503  Mismatch repair",
			"children":[
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H02565  Hereditary nonpolyposis colorectal cancer"
			},
			{
				"name":"H02568  Polymerase proofreading-associated polyposis"
			},
			{
				"name":"H00876  Mismatch repair deficiency"
			},
			{
				"name":"H02566  Muir-Torre syndrome"
			},
			{
				"name":"H01025  Familial adenomatous polyposis"
			}
			]
		},
		{
			"name":"nt06506  Double-strand break repair",
			"children":[
			{
				"name":"H00005  Chronic lymphocytic leukemia"
			},
			{
				"name":"H02418  Non-Hodgkin lymphoma"
			},
			{
				"name":"H00019  Pancreatic cancer"
			},
			{
				"name":"H00038  Melanoma"
			},
			{
				"name":"H00031  Breast cancer"
			},
			{
				"name":"H02531  Familial breast-ovarian cancer"
			},
			{
				"name":"H01132  Aplastic anemia"
			},
			{
				"name":"H00238  Fanconi anemia"
			},
			{
				"name":"H00507  Dyskeratosis congenita"
			},
			{
				"name":"H02569  Pulmonary fibrosis and\/or bone marrow failure, telomere-related"
			},
			{
				"name":"H00091  T-B+Severe combined immunodeficiency"
			},
			{
				"name":"H00092  T-B-Severe combined immunodeficiency"
			},
			{
				"name":"H01244  T+B+Severe combined immunodeficiencies (SCIDs)"
			},
			{
				"name":"H02554  Omenn syndrome"
			},
			{
				"name":"H00924  Severe combined immunodeficiency with microcephaly, growth retardation, and sensitivity to ionizing radiation"
			},
			{
				"name":"H02015  LIG4 syndrome"
			},
			{
				"name":"H00064  Ataxia telangiectasia"
			},
			{
				"name":"H00094  Immunodeficiency associated with DNA repair defects"
			},
			{
				"name":"H00296  Defects in RecQ helicases"
			},
			{
				"name":"H00962  RIDDLE syndrome"
			},
			{
				"name":"H01344  Nijmegen breakage syndrome"
			},
			{
				"name":"H01346  Bloom syndrome"
			},
			{
				"name":"H02014  Ataxia-telangiectasia-like syndrome"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H01118  Progressive external ophthalmoplegia"
			},
			{
				"name":"H01395  Autosomal recessive progressive external ophthalmoplegia"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00627  Premature ovarian failure"
			},
			{
				"name":"H01282  Spermatogenic failure"
			},
			{
				"name":"H00599  Ovarian dysgenesis"
			},
			{
				"name":"H02492  Microcephaly, growth restriction, and increased sister chromatid exchange"
			},
			{
				"name":"H00992  Seckel syndrome"
			},
			{
				"name":"H01993  Baller-Gerold syndrome"
			},
			{
				"name":"H01889  Meier-Gorlin syndrome"
			},
			{
				"name":"H01733  Werner syndrome"
			},
			{
				"name":"H01734  Rothmund-Thomson syndrome"
			},
			{
				"name":"H02576  Familial cutaneous telangiectasia and cancer syndrome"
			},
			{
				"name":"H00965  RAPADILINO syndrome"
			},
			{
				"name":"H02578  Short stature, microcephaly, and endocrine dysfunction"
			},
			{
				"name":"H02639  Atelis syndrome"
			},
			{
				"name":"H01623  MDPL syndrome"
			}
			]
		},
		{
			"name":"nt06508  Interstrand crosslink repair",
			"children":[
			{
				"name":"H00019  Pancreatic cancer"
			},
			{
				"name":"H00031  Breast cancer"
			},
			{
				"name":"H02531  Familial breast-ovarian cancer"
			},
			{
				"name":"H00238  Fanconi anemia"
			},
			{
				"name":"H02569  Pulmonary fibrosis and\/or bone marrow failure, telomere-related"
			},
			{
				"name":"H00627  Premature ovarian failure"
			},
			{
				"name":"H02577  Karyomegalic interstitial nephritis"
			},
			{
				"name":"H00599  Ovarian dysgenesis"
			},
			{
				"name":"H00992  Seckel syndrome"
			},
			{
				"name":"H01428  Xeroderma pigmentosum"
			},
			{
				"name":"H00076  Cockayne syndrome"
			},
			{
				"name":"H02570  Cerebro-oculo-facio-skeletal syndrome"
			},
			{
				"name":"H02576  Familial cutaneous telangiectasia and cancer syndrome"
			}
			]
		},
		{
			"name":"nt06547  Spliceosome",
			"children":[
			{
				"name":"H01847  Thrombocytopenia-absent radius syndrome"
			},
			{
				"name":"H02526  Disorders of adaptive immunity"
			},
			{
				"name":"H02031  Inclusion body myopathy with Paget disease of bone and frontotemporal dementia"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H00658  X-linked syndromic intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H01577  Essential tremor"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H00455  Spinal muscular atrophy"
			},
			{
				"name":"H00593  Limb-girdle muscular dystrophy"
			},
			{
				"name":"H00594  Distal myopathy"
			},
			{
				"name":"H00527  Retinitis pigmentosa"
			},
			{
				"name":"H00704  Oculopharyngeal muscular dystrophy"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00866  Trichothiodystrophy"
			},
			{
				"name":"H00786  Hypotrichosis"
			},
			{
				"name":"H00897  Pontocerebellar hypoplasia"
			},
			{
				"name":"H03033  Progressive microcephaly with simplified gyral pattern and cerebellar hypoplasia"
			},
			{
				"name":"H02745  Neuromuscular oculoauditory syndrome"
			},
			{
				"name":"H02422  Retinitis pigmentosa with skeletal anomalies"
			},
			{
				"name":"H01843  Cerebrocostomandibular syndrome"
			},
			{
				"name":"H01376  Acrofacial dysostosis"
			},
			{
				"name":"H02299  Arthrogryposis multiplex congenita"
			},
			{
				"name":"H02912  Achalasia-progeroid syndrome"
			},
			{
				"name":"H01195  VACTERL\/VATER association"
			},
			{
				"name":"H01838  Mandibulofacial dysostosis with microcephaly"
			},
			{
				"name":"H02673  Craniofacial microsomia"
			},
			{
				"name":"H01839  Burn-McKeown syndrome"
			},
			{
				"name":"H01930  Au-Kline syndrome"
			},
			{
				"name":"H02253  Beaulieu-Boycott-Innes syndrome"
			},
			{
				"name":"H02503  Richieri-Costa-Pereira syndrome"
			},
			{
				"name":"H01800  Verheij syndrome"
			},
			{
				"name":"H01913  Renpenning syndrome"
			},
			{
				"name":"H02804  ReNU syndrome"
			},
			{
				"name":"H02983  Leukodystrophy and cerebellar atrophy"
			},
			{
				"name":"H02986  Neurodevelopmental disorder with microcephaly, cataracts, and renal abnormalities"
			},
			{
				"name":"H02987  Neurodevelopmental disorder with cerebellar atrophy and motor dysfunction"
			},
			{
				"name":"H02993  Developmental delay, dysmorphic facies, and brain anomalies"
			},
			{
				"name":"H02997  Neurodevelopmental disorder with seizures and joint laxity"
			},
			{
				"name":"H02998  Neurodevelopmental disorder with hypotonia, feeding difficulties, facial dysmorphism, and brain abnormalities"
			},
			{
				"name":"H03017  Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects"
			},
			{
				"name":"H03018  Neurodevelopmental disorder with dysmorphic facies and skeletal and brain abnormalities"
			},
			{
				"name":"H03019  Neurodevelopmental disorder with hypotonia, craniofacial abnormalities, and seizures"
			}
			]
		},
		{
			"name":"nt06523  Epigenetic regulation by Polycomb complexes",
			"children":[
			{
				"name":"H01481  Myelodysplastic syndrome"
			},
			{
				"name":"H01510  Malignant paraganglioma"
			},
			{
				"name":"H00247  Multiple endocrine neoplasia syndrome"
			},
			{
				"name":"H02624  Tumor predisposition syndrome"
			},
			{
				"name":"H02222  Methylmalonic acidemia and hyperhomocysteinemia, cblX type"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H02490  Gabriele-de Vries syndrome"
			},
			{
				"name":"H00627  Premature ovarian failure"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H02170  Microphthalmia, syndromic"
			},
			{
				"name":"H02047  Bohring-Opitz syndrome"
			},
			{
				"name":"H01751  Weaver syndrome"
			},
			{
				"name":"H02477  Cohen-Gibson syndrome"
			},
			{
				"name":"H02522  Imagawa-Matsumoto syndrome"
			},
			{
				"name":"H00504  Rubinstein-Taybi syndrome"
			},
			{
				"name":"H00907  Kleefstra syndrome"
			},
			{
				"name":"H02382  Bainbridge-Ropers syndrome"
			},
			{
				"name":"H02619  Hypotonia, ataxia, developmental delay, and tooth enamel defect syndrome"
			},
			{
				"name":"H02650  Menke-Hennekam syndrome"
			},
			{
				"name":"H02528  Hao-Fountain syndrome"
			},
			{
				"name":"H02587  Luo-Schoch-Yamamoto syndrome"
			},
			{
				"name":"H02611  Turnpenny-Fry syndrome"
			},
			{
				"name":"H02617  Bryant-Li-Bhoj neurodevelopmental syndrome"
			},
			{
				"name":"H02618  Developmental delay with variable intellectual disability and dysmorphic facies"
			},
			{
				"name":"H02622  Shukla-Vernon syndrome"
			},
			{
				"name":"H02623  Kury-Isidor syndrome"
			},
			{
				"name":"H02635  Poirier-Bienvenu neurodevelopmental syndrome"
			},
			{
				"name":"H02854  Okur-Chung neurodevelopmental syndrome"
			},
			{
				"name":"H02855  Shashi-Pena syndrome"
			}
			]
		}
		]
	},
	{
		"name":"Signal transduction",
		"children":[
		{
			"name":"nt06526  MAPK signaling",
			"children":[
			{
				"name":"H00042  Glioma"
			},
			{
				"name":"H00004  Chronic myeloid leukemia"
			},
			{
				"name":"H02541  Juvenile myelomonocytic leukemia"
			},
			{
				"name":"H00003  Acute myeloid leukemia"
			},
			{
				"name":"H00018  Gastric cancer"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00019  Pancreatic cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00014  Non-small cell lung cancer"
			},
			{
				"name":"H00013  Small cell lung cancer"
			},
			{
				"name":"H00038  Melanoma"
			},
			{
				"name":"H00039  Basal cell carcinoma"
			},
			{
				"name":"H00031  Breast cancer"
			},
			{
				"name":"H00026  Endometrial cancer"
			},
			{
				"name":"H00022  Bladder cancer"
			},
			{
				"name":"H00032  Thyroid cancer"
			},
			{
				"name":"H01592  Medullary thyroid cancer"
			},
			{
				"name":"H01510  Malignant paraganglioma"
			},
			{
				"name":"H00247  Multiple endocrine neoplasia syndrome"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H01250  Hereditary gingival fibromatosis"
			},
			{
				"name":"H02188  Watson syndrome"
			},
			{
				"name":"H02043  Capillary malformation-arteriovenous malformation"
			},
			{
				"name":"H00910  Hirschsprung disease"
			},
			{
				"name":"H00471  Split-hand\/foot malformation"
			},
			{
				"name":"H02631  Melorheostosis"
			},
			{
				"name":"H02157  Short-rib thoracic dysplasia"
			},
			{
				"name":"H01756  Pfeiffer syndrome"
			},
			{
				"name":"H01754  Crouzon syndrome"
			},
			{
				"name":"H01755  Apert syndrome"
			},
			{
				"name":"H01753  Antley-Bixler syndrome"
			},
			{
				"name":"H01988  Jackson-Weiss syndrome"
			},
			{
				"name":"H01989  Beare-Stevenson syndrome"
			},
			{
				"name":"H01990  Muenke syndrome"
			},
			{
				"name":"H01991  Saethre-Chotzen syndrome"
			},
			{
				"name":"H00532  Parkes Weber syndrome"
			},
			{
				"name":"H01986  Legius syndrome"
			},
			{
				"name":"H02189  Neurofibromatosis-Noonan syndrome"
			},
			{
				"name":"H01437  Neurofibromatosis type 1"
			},
			{
				"name":"H01738  Noonan syndrome"
			},
			{
				"name":"H00523  Noonan syndrome and related disorders"
			},
			{
				"name":"H00574  Coffin-Lowry syndrome"
			},
			{
				"name":"H01745  Cardiofaciocutaneous syndrome"
			},
			{
				"name":"H01747  Costello syndrome"
			},
			{
				"name":"H01984  Leopard syndrome"
			},
			{
				"name":"H02190  CBL syndrome"
			},
			{
				"name":"H02191  Noonan-like syndrome with loose anagen hair"
			}
			]
		},
		{
			"name":"nt06530  PI3K signaling",
			"children":[
			{
				"name":"H00003  Acute myeloid leukemia"
			},
			{
				"name":"H00031  Breast cancer"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H01909  Hypoinsulinemic hypoglycemia with hemihypertrophy"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H00848  Ataxia with ocular apraxia"
			},
			{
				"name":"H01807  Hereditary diffuse leukoencephalopathy with spheroids"
			},
			{
				"name":"H00534  Cerebral cavernous malformation"
			},
			{
				"name":"H01282  Spermatogenic failure"
			},
			{
				"name":"H02647  Macrodactyly"
			},
			{
				"name":"H02627  Epidermal nevus"
			},
			{
				"name":"H02723  Macrocephaly\/autism syndrome"
			},
			{
				"name":"H01885  Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome"
			},
			{
				"name":"H01912  Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi"
			},
			{
				"name":"H02119  Proteus syndrome"
			},
			{
				"name":"H02153  Megalencephaly-capillary malformation syndrome"
			},
			{
				"name":"H02297  CLAPO syndrome"
			},
			{
				"name":"H01222  Cowden syndrome"
			},
			{
				"name":"H02632  Houge-Janssens syndrome"
			}
			]
		},
		{
			"name":"nt06505  WNT signaling",
			"children":[
			{
				"name":"H00113  Salmonellosis"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00018  Gastric cancer"
			},
			{
				"name":"H03037  Gastric adenocarcinoma and proximal polyposis of the stomach"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00026  Endometrial cancer"
			},
			{
				"name":"H01025  Familial adenomatous polyposis"
			},
			{
				"name":"H00535  Lymphatic malformation"
			},
			{
				"name":"H01307  Nonsyndromic congenital nail disorder"
			},
			{
				"name":"H03009  Yellow nail syndrome"
			},
			{
				"name":"H01774  Hyperostosis corticalis generalisata"
			},
			{
				"name":"H02609  Craniodiaphyseal dysplasia"
			},
			{
				"name":"H01593  Osteoporosis"
			},
			{
				"name":"H01027  Microphthalmia"
			},
			{
				"name":"H00589  Familial exudative vitreoretinopathy"
			},
			{
				"name":"H00625  Tooth agenesis"
			},
			{
				"name":"H00482  Brachydactyly"
			},
			{
				"name":"H00471  Split-hand\/foot malformation"
			},
			{
				"name":"H00636  Tetra-amelia syndrome"
			},
			{
				"name":"H00436  Osteopetrosis"
			},
			{
				"name":"H00486  Sclerosteosis"
			},
			{
				"name":"H00479  Metaphyseal dysplasias"
			},
			{
				"name":"H00485  Robinow syndrome"
			},
			{
				"name":"H02154  Omodysplasia"
			},
			{
				"name":"H00506  Osteogenesis imperfecta"
			},
			{
				"name":"H00451  Osteoporosis-pseudoglioma syndrome"
			},
			{
				"name":"H00853  Cenani-Lenz syndactyly syndrome"
			},
			{
				"name":"H00846  Fuhrmann syndrome"
			},
			{
				"name":"H00847  Al-Awadi\/Raas-Rothschild syndrome"
			},
			{
				"name":"H02456  Ectodermal dysplasia"
			},
			{
				"name":"H00646  Odontoonychodermal dysplasia"
			},
			{
				"name":"H00781  Schopf-Schulz-Passarge syndrome"
			},
			{
				"name":"H00857  Oligodontia-colorectal cancer syndrome"
			},
			{
				"name":"H00949  Focal dermal hypoplasia"
			}
			]
		},
		{
			"name":"nt06511  NOTCH signaling",
			"children":[
			{
				"name":"H00030  Cervical cancer"
			},
			{
				"name":"H01910  Infantile myofibromatosis"
			},
			{
				"name":"H02467  Neonatal inflammatory skin and bowel disease"
			},
			{
				"name":"H00536  Cerebral autosomal dominant arteriopathy with subcortical infarcts and leucoencephalopathy"
			},
			{
				"name":"H01757  Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy"
			},
			{
				"name":"H01216  Left ventricular noncompaction"
			},
			{
				"name":"H00786  Hypotrichosis"
			},
			{
				"name":"H00681  Acne inversa"
			},
			{
				"name":"H00623  Hajdu-Cheney syndrome"
			},
			{
				"name":"H01893  Lateral meningocele syndrome"
			},
			{
				"name":"H00549  Tetralogy of Fallot"
			},
			{
				"name":"H00554  Aortic valve disease"
			},
			{
				"name":"H00551  Alagille syndrome"
			},
			{
				"name":"H00517  Spondylocostal dysostosis"
			},
			{
				"name":"H01413  Adams-Oliver syndrome"
			}
			]
		},
		{
			"name":"nt06501  HH signaling",
			"children":[
			{
				"name":"H00039  Basal cell carcinoma"
			},
			{
				"name":"H00267  Holoprosencephaly"
			},
			{
				"name":"H00263  Acrocallosal syndrome"
			},
			{
				"name":"H01835  Neuronal migration disorder"
			},
			{
				"name":"H01027  Microphthalmia"
			},
			{
				"name":"H00482  Brachydactyly"
			},
			{
				"name":"H01852  Postaxial polydactyly"
			},
			{
				"name":"H02332  Preaxial polydactyly"
			},
			{
				"name":"H00530  Joubert syndrome and related disorders"
			},
			{
				"name":"H00675  Acrocapitofemoral dysplasia"
			},
			{
				"name":"H02158  Weyers acrofacial dysostosis"
			},
			{
				"name":"H02161  Greig cephalopolysyndactyly syndrome"
			},
			{
				"name":"H00503  Ellis-van Creveld syndrome"
			},
			{
				"name":"H00895  Basal cell nevus syndrome"
			},
			{
				"name":"H00502  Pallister-Hall syndrome"
			},
			{
				"name":"H00886  Donnai-Barrow syndrome"
			},
			{
				"name":"H01265  Hydrolethalus syndrome"
			},
			{
				"name":"H02479  Nivelon-Nivelon-Mabille syndrome"
			}
			]
		},
		{
			"name":"nt06507  TGFB signaling",
			"children":[
			{
				"name":"H00009  Adult T-cell leukemia"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H01023  Juvenile polyposis syndrome"
			},
			{
				"name":"H01024  Hereditary mixed polyposis syndrome"
			},
			{
				"name":"H00211  Hemochromatosis"
			},
			{
				"name":"H01619  Primary pulmonary hypertension"
			},
			{
				"name":"H00801  Familial thoracic aortic aneurysm and dissection"
			},
			{
				"name":"H00430  Fibrodysplasia ossificans progressiva"
			},
			{
				"name":"H02452  Muscle hypertrophy"
			},
			{
				"name":"H00625  Tooth agenesis"
			},
			{
				"name":"H00632  Heterotaxy"
			},
			{
				"name":"H00533  Hereditary hemorrhagic telangiectasia"
			},
			{
				"name":"H00599  Ovarian dysgenesis"
			},
			{
				"name":"H00482  Brachydactyly"
			},
			{
				"name":"H00484  Multiple synostosis syndrome"
			},
			{
				"name":"H00851  Proximal symphalangism"
			},
			{
				"name":"H00434  Camurati-Engelmann disease"
			},
			{
				"name":"H00900  Geleophysic dysplasia"
			},
			{
				"name":"H02543  Acromesomelic dysplasia"
			},
			{
				"name":"H00778  Tarsal-carpal coalition syndrome"
			},
			{
				"name":"H00653  Marfan syndrome"
			},
			{
				"name":"H00800  Loeys-Dietz syndrome"
			},
			{
				"name":"H00609  Persistent Mullerian duct syndrome"
			},
			{
				"name":"H02102  Myhre syndrome"
			}
			]
		},
		{
			"name":"nt06518  JAK-STAT signaling",
			"children":[
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H01109  Chronic mucocutaneous candidiasis"
			},
			{
				"name":"H01605  Myelofibrosis"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00009  Adult T-cell leukemia"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00236  Congenital polycythemia"
			},
			{
				"name":"H01612  Essential thrombocythemia"
			},
			{
				"name":"H02525  Disorders of innate immunity"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H00089  IFN-gamma\/IL-12 axis"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H00091  T-B+Severe combined immunodeficiency"
			},
			{
				"name":"H01968  Hyper-IgE syndrome"
			},
			{
				"name":"H02540  Infantile-onset multisystem autoimmune disease"
			},
			{
				"name":"H02537  Autoinflammation, immune dysregulation, and eosinophilia"
			},
			{
				"name":"H00100  Neutropenic disorders"
			},
			{
				"name":"H01388  Hyperprolactinemia"
			},
			{
				"name":"H00931  Growth hormone insensitivity with immunodeficiency"
			},
			{
				"name":"H02035  Isolated growth hormone deficiency"
			},
			{
				"name":"H02037  Laron syndrome"
			},
			{
				"name":"H02059  Leptin deficiency"
			},
			{
				"name":"H02060  Leptin receptor deficiency"
			},
			{
				"name":"H01217  Primary localized cutaneous amyloidosis"
			},
			{
				"name":"H00935  Cold-induced sweating syndrome"
			},
			{
				"name":"H01122  Congenital pulmonary alveolar proteinosis"
			},
			{
				"name":"H01227  Inflammatory bowel disease (IBD)"
			},
			{
				"name":"H00840  Pseudo-TORCH syndrome"
			},
			{
				"name":"H00462  Stuve-Wiedemann syndrome"
			}
			]
		},
		{
			"name":"nt06516  TNF signaling",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00278  Enteropathogenic Escherichia coli (EPEC) infection"
			},
			{
				"name":"H00277  Enterohemorrhagic Escherichia coli (EHEC) infection"
			},
			{
				"name":"H00113  Salmonellosis"
			},
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00009  Adult T-cell leukemia"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00030  Cervical cancer"
			},
			{
				"name":"H02525  Disorders of innate immunity"
			},
			{
				"name":"H02620  Autoinflammation with episodic fever and lymphadenopathy"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H00086  Immunodeficiency with hyper-IgM"
			},
			{
				"name":"H00088  Common variable immunodeficiency"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H01969  X-linked lymphoproliferative syndrome"
			},
			{
				"name":"H01970  Lymphoproliferative syndrome"
			},
			{
				"name":"H02592  Familial Behcet-like autoinflammatory syndrome"
			},
			{
				"name":"H02593  Chronic mucocutaneous ulceration"
			},
			{
				"name":"H00912  Tumor necrosis factor receptor-associated periodic syndrome"
			},
			{
				"name":"H01744  Polyglucosan body myopathy"
			},
			{
				"name":"H02414  Autoinflammation, panniculitis, and dermatosis syndrome"
			},
			{
				"name":"H01490  Multiple sclerosis"
			},
			{
				"name":"H00437  Paget disease of bone"
			},
			{
				"name":"H02042  Familial expansile osteolysis"
			},
			{
				"name":"H00625  Tooth agenesis"
			},
			{
				"name":"H00436  Osteopetrosis"
			},
			{
				"name":"H00651  Hypohidrotic ectodermal dysplasia"
			},
			{
				"name":"H00645  Incontinentia pigmenti"
			},
			{
				"name":"H00540  Osteoporosis, lymphedema, anhydrotic ectodermal dysplasia with immunodeficiency (OLEDAID)"
			}
			]
		},
		{
			"name":"nt06528  Calcium signaling",
			"children":[
			{
				"name":"H00042  Glioma"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00014  Non-small cell lung cancer"
			},
			{
				"name":"H02259  Stormorken syndrome"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H01603  Primary aldosteronism"
			},
			{
				"name":"H00144  Mucolipidosis IV"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H02865  Neurodevelopmental disorder with or without hyperkinetic movements and seizures"
			},
			{
				"name":"H00749  Episodic ataxias"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H00808  Idiopathic generalized epilepsies"
			},
			{
				"name":"H01514  Landau-Kleffner syndrome"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H02150  Infantile or early childhood epileptic encephalopathy"
			},
			{
				"name":"H00775  Hemiplegic migraine"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H02258  Tubular aggregate myopathy"
			},
			{
				"name":"H02320  Vacuolar myopathy with CASQ1 aggregates"
			},
			{
				"name":"H00215  Periodic paralysis"
			},
			{
				"name":"H01129  Brody myopathy"
			},
			{
				"name":"H00481  Cone-rod dystrophy and cone dystrophy"
			},
			{
				"name":"H00690  Aland Island eye disease"
			},
			{
				"name":"H00787  Congenital stationary night blindness"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00292  Hypertrophic cardiomyopathy"
			},
			{
				"name":"H00293  Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"H00720  Long QT syndrome"
			},
			{
				"name":"H00728  Brugada syndrome"
			},
			{
				"name":"H01019  Catecholaminergic polymorphic ventricular tachycardia"
			},
			{
				"name":"H02636  Sinoatrial node dysfunction and deafness"
			},
			{
				"name":"H00801  Familial thoracic aortic aneurysm and dissection"
			},
			{
				"name":"H00715  Darier disease"
			},
			{
				"name":"H00755  Acrokeratosis verruciformis"
			},
			{
				"name":"H01307  Nonsyndromic congenital nail disorder"
			},
			{
				"name":"H02281  Isolated anhidrosis with normal sweat glands"
			},
			{
				"name":"H01869  Megacystis microcolon intestinal hypoperistalsis syndrome"
			},
			{
				"name":"H02641  Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development"
			},
			{
				"name":"H02856  Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures"
			},
			{
				"name":"H02858  Neurodevelopmental disorder with speech impairment and with or without seizures"
			},
			{
				"name":"H02859  Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements"
			}
			]
		},
		{
			"name":"nt06522  mTOR signaling",
			"children":[
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H01692  Subependymal giant cell astrocytoma"
			},
			{
				"name":"H00030  Cervical cancer"
			},
			{
				"name":"H01691  Renal angiomyolipoma"
			},
			{
				"name":"H01210  Hypomagnesemia"
			},
			{
				"name":"H02214  Familial focal epilepsy with variable foci"
			},
			{
				"name":"H02697  Long-Olsen-Distelmaier syndrome"
			},
			{
				"name":"H00896  Lymphangioleiomyomatosis"
			},
			{
				"name":"H02446  Autosomal recessive macrocephaly\/megalencephaly syndrome"
			},
			{
				"name":"H01251  Focal cortical dysplasia of Taylor"
			},
			{
				"name":"H01789  You-Hoover-Fong syndrome"
			},
			{
				"name":"H00818  Birt-Hogg-Dube syndrome"
			},
			{
				"name":"H00666  Peutz-Jeghers syndrome"
			},
			{
				"name":"H00915  Tuberous sclerosis complex"
			},
			{
				"name":"H01928  Smith-Kingsmore syndrome"
			},
			{
				"name":"H03095  Neurodevelopmental disorder with microcephaly and movement abnormalities"
			},
			{
				"name":"H01112  Polyhydramnios, megalencephaly, and symptomatic epilepsy"
			}
			]
		},
		{
			"name":"nt06542  HIF signaling",
			"children":[
			{
				"name":"H00021  Renal cell carcinoma"
			},
			{
				"name":"H00236  Congenital polycythemia"
			},
			{
				"name":"H00559  von Hippel-Lindau syndrome"
			}
			]
		},
		{
			"name":"nt06543  NRG-ERBB signaling",
			"children":[
			{
				"name":"H00019  Pancreatic cancer"
			},
			{
				"name":"H00014  Non-small cell lung cancer"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			}
			]
		},
		{
			"name":"nt06544  Neuroactive ligand signaling",
			"children":[
			{
				"name":"H01235  Bleeding disorder platelet-type"
			},
			{
				"name":"H00420  Familial partial lipodystrophy"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H02773  Menstrual cycle-dependent periodic fever"
			},
			{
				"name":"H02105  Prohormone convertase 1\/3 deficiency"
			},
			{
				"name":"H02106  Genetic obesity"
			},
			{
				"name":"H02419  Glycine encephalopathy with normal serum glycine"
			},
			{
				"name":"H02311  Molybdenum cofactor deficiency"
			},
			{
				"name":"H00923  Congenital systemic glutamine deficiency"
			},
			{
				"name":"H02846  Global developmental delay, progressive ataxia, and elevated glutamine"
			},
			{
				"name":"H02847  CASGID syndrome"
			},
			{
				"name":"H01161  Aromatic L-amino acid decarboxylase deficiency"
			},
			{
				"name":"H00548  Brunner syndrome"
			},
			{
				"name":"H01257  GABA-transaminase deficiency"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H00658  X-linked syndromic intellectual developmental disorder"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H02111  Autism"
			},
			{
				"name":"H01895  Attention deficit hyperactivity disorder (ADHD)"
			},
			{
				"name":"H02865  Neurodevelopmental disorder with or without hyperkinetic movements and seizures"
			},
			{
				"name":"H01649  Schizophrenia"
			},
			{
				"name":"H01646  Major depressive disorder"
			},
			{
				"name":"H01450  Obsessive-compulsive disorder"
			},
			{
				"name":"H01611  Alcohol dependence"
			},
			{
				"name":"H02849  Familial natural short sleep"
			},
			{
				"name":"H02557  Dopa-responsive dystonia"
			},
			{
				"name":"H02676  Infantile-onset parkinsonism-dystonia"
			},
			{
				"name":"H00749  Episodic ataxias"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H01577  Essential tremor"
			},
			{
				"name":"H00862  Tourette syndrome"
			},
			{
				"name":"H00808  Idiopathic generalized epilepsies"
			},
			{
				"name":"H02889  X-linked epilepsy-2 with or without impaired intellectual development and dysmorphic features"
			},
			{
				"name":"H01819  Early myoclonic encephalopathy"
			},
			{
				"name":"H02215  Childhood absence epilepsy"
			},
			{
				"name":"H02564  Generalized epilepsy with febrile seizures plus"
			},
			{
				"name":"H00807  Nocturnal frontal lobe epilepsy"
			},
			{
				"name":"H01514  Landau-Kleffner syndrome"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00783  Febrile seizures"
			},
			{
				"name":"H00775  Hemiplegic migraine"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H00856  Distal hereditary motor neuropathies"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00770  Congenital myasthenic syndrome"
			},
			{
				"name":"H01031  Orthostatic intolerance"
			},
			{
				"name":"H00787  Congenital stationary night blindness"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H02751  Orthostatic hypotension"
			},
			{
				"name":"H02895  Lodder-Merla syndrome"
			},
			{
				"name":"H01933  Porokeratosis"
			},
			{
				"name":"H01256  Foveal hypoplasia"
			},
			{
				"name":"H02796  Autonomic bladder dysfunction with impaired pupillary reflex and secondary CAKUT"
			},
			{
				"name":"H02236  Keppen-Lubinsky syndrome"
			},
			{
				"name":"H02129  Prune belly syndrome"
			},
			{
				"name":"H00756  Pitt-Hopkins syndrome"
			},
			{
				"name":"H01238  Phelan-McDermid syndrome"
			},
			{
				"name":"H00769  Hyperekplexia"
			},
			{
				"name":"H02859  Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements"
			},
			{
				"name":"H02885  Neurodevelopmental disorder with hypotonia and dysmorphic facies"
			},
			{
				"name":"H02886  Neurodevelopmental disorder with seizures, hypotonia, and brain imaging abnormalities"
			},
			{
				"name":"H02887  Neurodevelopmental disorder with language impairment and behavioral abnormalities"
			},
			{
				"name":"H02888  Neurodevelopmental disorder with or without seizures and gait abnormalities"
			},
			{
				"name":"H02890  Neurodevelopmental disorder with language delay and variable cognitive abnormalities"
			},
			{
				"name":"H02891  Neurodevelopmental disorder with poor language and loss of hand skills"
			},
			{
				"name":"H02892  Neurodevelopmental disorder with infantile epileptic spasms"
			},
			{
				"name":"H02894  Neurodevelopmental disorder with impaired language and ataxia and with or without seizures"
			}
			]
		}
		]
	},
	{
		"name":"Cellular processes",
		"children":[
		{
			"name":"nt06546  IgSF CAM signaling",
			"children":[
			{
				"name":"H00342  Tuberculosis"
			},
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H00842  Epidermodysplasia verruciformis"
			},
			{
				"name":"H00361  Malaria"
			},
			{
				"name":"H02541  Juvenile myelomonocytic leukemia"
			},
			{
				"name":"H00017  Esophageal cancer"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00039  Basal cell carcinoma"
			},
			{
				"name":"H00032  Thyroid cancer"
			},
			{
				"name":"H00222  Congenital fibrinogen deficiency"
			},
			{
				"name":"H01235  Bleeding disorder platelet-type"
			},
			{
				"name":"H00226  Glanzmann thrombasthenia"
			},
			{
				"name":"H00233  MYH9-related disease"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H01969  X-linked lymphoproliferative syndrome"
			},
			{
				"name":"H02036  Combined pituitary hormone deficiency"
			},
			{
				"name":"H00624  Progressive familial intrahepatic cholestasis"
			},
			{
				"name":"H01185  Cerebral amyloid angiopathy"
			},
			{
				"name":"H00845  Familial amyloidosis"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H02111  Autism"
			},
			{
				"name":"H01882  Asperger syndrome"
			},
			{
				"name":"H02990  Neurodevelopmental disorder with central and peripheral motor dysfunction"
			},
			{
				"name":"H00864  Trichotillomania"
			},
			{
				"name":"H01574  Familial idiopathic basal ganglia calcification"
			},
			{
				"name":"H00749  Episodic ataxias"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H00862  Tourette syndrome"
			},
			{
				"name":"H02789  Familial myoclonus"
			},
			{
				"name":"H01287  Congenital mirror movements"
			},
			{
				"name":"H00056  Alzheimer disease"
			},
			{
				"name":"H02980  Cognitive impairment with or without cerebellar ataxia"
			},
			{
				"name":"H02696  Early-onset epilepsy"
			},
			{
				"name":"H00806  Benign familial neonatal seizure"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H02362  Benign familial infantile seizure"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H02178  MASA syndrome"
			},
			{
				"name":"H00856  Distal hereditary motor neuropathies"
			},
			{
				"name":"H01436  Guillain-Barre syndrome"
			},
			{
				"name":"H02357  Congenital hypomyelinating neuropathy"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H01155  Roussy-Levy syndrome"
			},
			{
				"name":"H01296  Hereditary neuropathy with liability to pressure palsies"
			},
			{
				"name":"H02359  Dejerine-Sottas disease"
			},
			{
				"name":"H02817  Peripheral neuropathy, myopathy, hoarseness, and hearing loss"
			},
			{
				"name":"H01777  Schwartz-Jampel syndrome"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H00594  Distal myopathy"
			},
			{
				"name":"H02989  Developmental delay with or without epilepsy"
			},
			{
				"name":"H02450  Horizontal gaze palsy with progressive scoliosis"
			},
			{
				"name":"H00776  Congenital motor nystagmus (CMN)"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00292  Hypertrophic cardiomyopathy"
			},
			{
				"name":"H00720  Long QT syndrome"
			},
			{
				"name":"H01935  Familial hypercholanemia"
			},
			{
				"name":"H00630  Rheumatoid arthritis"
			},
			{
				"name":"H01657  Nephrotic syndrome"
			},
			{
				"name":"H01037  Vesicoureteral reflux"
			},
			{
				"name":"H01477  Congenital short bowel syndrome"
			},
			{
				"name":"H02458  Hydrocephalus due to congenital stenosis of aqueduct of Sylvius"
			},
			{
				"name":"H00516  Cleft lip and\/or cleft palate"
			},
			{
				"name":"H00554  Aortic valve disease"
			},
			{
				"name":"H02043  Capillary malformation-arteriovenous malformation"
			},
			{
				"name":"H02811  Aplasia or hypoplasia of the breasts and\/or nipples"
			},
			{
				"name":"H01921  MICPCH syndrome"
			},
			{
				"name":"H02132  Microcephaly syndrome"
			},
			{
				"name":"H01034  L1 syndrome"
			},
			{
				"name":"H02155  Dyssegmental dysplasia"
			},
			{
				"name":"H01828  Opsismodysplasia"
			},
			{
				"name":"H02154  Omodysplasia"
			},
			{
				"name":"H01008  C syndrome"
			},
			{
				"name":"H00865  Lethal congenital contractural syndrome"
			},
			{
				"name":"H02456  Ectodermal dysplasia"
			},
			{
				"name":"H00647  Ectodermal dysplasia-syndactyly syndrome"
			},
			{
				"name":"H01215  Simpson-Golabi-Behmel syndrome"
			},
			{
				"name":"H01738  Noonan syndrome"
			},
			{
				"name":"H00756  Pitt-Hopkins syndrome"
			},
			{
				"name":"H00894  FG syndrome"
			},
			{
				"name":"H01869  Megacystis microcolon intestinal hypoperistalsis syndrome"
			},
			{
				"name":"H01984  Leopard syndrome"
			},
			{
				"name":"H02074  Knobloch syndrome"
			},
			{
				"name":"H02667  Takenouchi-Kosaki syndrome"
			},
			{
				"name":"H02981  Neurooculorenal syndrome"
			},
			{
				"name":"H02982  Congenital heart defects and skeletal malformations syndrome"
			},
			{
				"name":"H02326  Keipert syndrome"
			},
			{
				"name":"H02355  Deafness and myopia"
			},
			{
				"name":"H02397  Neurodevelopmental disorder with movement abnormalities or hypotonia"
			},
			{
				"name":"H02463  Syndromic intellectual developmental disorder"
			},
			{
				"name":"H02911  Paul-Chao neurodevelopmental syndrome"
			},
			{
				"name":"H02988  Neurodevelopmental disorder with intracranial hemorrhage, seizures, and spasticity"
			},
			{
				"name":"H03077  Developmental delay, impaired speech, and behavioral abnormalities"
			},
			{
				"name":"H00626  Focal segmental glomerulosclerosis"
			},
			{
				"name":"H00099  Leukocyte adhesion deficiency"
			},
			{
				"name":"H01301  Hemorrhagic destruction of the brain, subependymal calcification, and cataracts"
			}
			]
		},
		{
			"name":"nt06548  Integrin signaling",
			"children":[
			{
				"name":"H00842  Epidermodysplasia verruciformis"
			},
			{
				"name":"H00361  Malaria"
			},
			{
				"name":"H02092  von Willebrand disease"
			},
			{
				"name":"H00222  Congenital fibrinogen deficiency"
			},
			{
				"name":"H01235  Bleeding disorder platelet-type"
			},
			{
				"name":"H00226  Glanzmann thrombasthenia"
			},
			{
				"name":"H02669  Inflammatory bowel disease, immunodeficiency, and encephalopathy"
			},
			{
				"name":"H00214  Hypophosphatemic rickets"
			},
			{
				"name":"H02139  Autosomal recessive hypophosphatemic rickets"
			},
			{
				"name":"H00845  Familial amyloidosis"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H00809  Familial epilepsy temporal lobe (ETL)"
			},
			{
				"name":"H00877  Brain small vessel disease"
			},
			{
				"name":"H02718  Autosomal dominant pontine microangiopathy and leukoencephalopathy"
			},
			{
				"name":"H00798  Familial carpal tunnel syndrome"
			},
			{
				"name":"H00593  Limb-girdle muscular dystrophy"
			},
			{
				"name":"H00590  Congenital muscular dystrophies (CMD\/MDC)"
			},
			{
				"name":"H01340  Bethlem myopathy"
			},
			{
				"name":"H01778  Ullrich disease"
			},
			{
				"name":"H01958  Merosin-deficient congenital muscular dystrophy"
			},
			{
				"name":"H01338  Myosclerosis"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H01209  Deafness, X-linked"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00535  Lymphatic malformation"
			},
			{
				"name":"H00218  Cystic fibrosis"
			},
			{
				"name":"H01276  Chronic idiopathic intestinal pseudo-obstruction"
			},
			{
				"name":"H00586  Epidermolysis bullosa, junctional"
			},
			{
				"name":"H00588  Kindler syndrome"
			},
			{
				"name":"H00813  Laryngo onycho cutaneous syndrome"
			},
			{
				"name":"H01173  Stiff skin syndrome"
			},
			{
				"name":"H02539  Intervertebral disc disease"
			},
			{
				"name":"H01526  Legg-Calve-Perthes Disease"
			},
			{
				"name":"H01529  Avascular necrosis of femoral head"
			},
			{
				"name":"H01593  Osteoporosis"
			},
			{
				"name":"H00576  Pierson syndrome"
			},
			{
				"name":"H01657  Nephrotic syndrome"
			},
			{
				"name":"H00582  Benign familial hematuria"
			},
			{
				"name":"H01037  Vesicoureteral reflux"
			},
			{
				"name":"H00270  Periventricular nodular heterotopia"
			},
			{
				"name":"H00839  Porencephaly"
			},
			{
				"name":"H02501  Occipital cortical malformation"
			},
			{
				"name":"H00662  Ectopia lentis"
			},
			{
				"name":"H02880  Retinal arterial tortuosity"
			},
			{
				"name":"H02852  Unilateral or bilateral isolated cryptophthalmos"
			},
			{
				"name":"H00615  Amelogenesis imperfecta"
			},
			{
				"name":"H02348  Dentin dysplasia"
			},
			{
				"name":"H00432  Hereditary dentine disorders"
			},
			{
				"name":"H02230  X-linked cardiac valvular dysplasia"
			},
			{
				"name":"H00822  Renal hypodysplasia and aplasia"
			},
			{
				"name":"H01207  Trigonocephaly"
			},
			{
				"name":"H02464  Poretti-Boltshauser syndrome"
			},
			{
				"name":"H00268  Lissencephaly"
			},
			{
				"name":"H03007  Nonprogressive neurodevelopmental disorder with spasticity and transient opisthotonus"
			},
			{
				"name":"H00673  Weill-Marchesani syndrome"
			},
			{
				"name":"H00579  Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)"
			},
			{
				"name":"H00520  Type II collagenopathies"
			},
			{
				"name":"H00434  Camurati-Engelmann disease"
			},
			{
				"name":"H00445  Osteoarthritis with mild chondrodysplasia"
			},
			{
				"name":"H00499  Spondylocarpotarsal synostosis syndrome"
			},
			{
				"name":"H00519  Spondyloepiphyseal dysplasia congenita"
			},
			{
				"name":"H02070  Kniest dysplasia"
			},
			{
				"name":"H02071  Czech dysplasia"
			},
			{
				"name":"H02187  Spondyloepimetaphyseal dysplasia"
			},
			{
				"name":"H02185  Spondylometaphyseal dysplasia"
			},
			{
				"name":"H02066  Achondrogenesis type II"
			},
			{
				"name":"H00477  Pseudoachondroplasia"
			},
			{
				"name":"H00476  Multiple epiphyseal dysplasia"
			},
			{
				"name":"H00900  Geleophysic dysplasia"
			},
			{
				"name":"H02228  Acromicric dysplasia"
			},
			{
				"name":"H02229  Terminal osseous dysplasia"
			},
			{
				"name":"H02629  Bent bone dysplasia syndrome"
			},
			{
				"name":"H02048  Larsen syndrome"
			},
			{
				"name":"H02064  Atelosteogenesis type I and III"
			},
			{
				"name":"H02067  Boomerang dysplasia"
			},
			{
				"name":"H00506  Osteogenesis imperfecta"
			},
			{
				"name":"H00456  Fronto-otopalatodigital syndromes"
			},
			{
				"name":"H02227  Frontometaphyseal dysplasia"
			},
			{
				"name":"H02474  Blepharocheilodontic syndrome"
			},
			{
				"name":"H00653  Marfan syndrome"
			},
			{
				"name":"H00661  MASS phenotype"
			},
			{
				"name":"H00802  Ehlers-Danlos syndrome"
			},
			{
				"name":"H02241  Ehlers-Danlos syndrome cardiac valvular type"
			},
			{
				"name":"H02243  Ehlers-Danlos syndrome arthrochalasia type"
			},
			{
				"name":"H02724  Combined osteogenesis imperfecta and Ehlers-Danlos syndrome"
			},
			{
				"name":"H00685  Bifid nose with or without anorectal and renal anomalies"
			},
			{
				"name":"H00686  Manitoba oculotrichoanal syndrome"
			},
			{
				"name":"H00894  FG syndrome"
			},
			{
				"name":"H02072  Stickler syndrome"
			},
			{
				"name":"H02500  Congenital interstitial lung disease with nephrotic syndrome and epidermolysis bullosa"
			},
			{
				"name":"H00687  Fraser syndrome"
			},
			{
				"name":"H00581  Alport syndrome"
			},
			{
				"name":"H01260  Glomerulopathy with fibronectin deposits"
			},
			{
				"name":"H00099  Leukocyte adhesion deficiency"
			}
			]
		},
		{
			"name":"nt06549  Cadherin signaling",
			"children":[
			{
				"name":"H01667  Medulloblastoma"
			},
			{
				"name":"H00018  Gastric cancer"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00027  Ovarian cancer"
			},
			{
				"name":"H00026  Endometrial cancer"
			},
			{
				"name":"H00947  Pilomatricoma"
			},
			{
				"name":"H01102  Pituitary adenomas"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H02526  Disorders of adaptive immunity"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H00409  Type 2 diabetes mellitus"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H01895  Attention deficit hyperactivity disorder (ADHD)"
			},
			{
				"name":"H00060  Dentatorubropallidoluysian atrophy (DRPLA)"
			},
			{
				"name":"H01255  Juvenile-onset dystonia"
			},
			{
				"name":"H00808  Idiopathic generalized epilepsies"
			},
			{
				"name":"H02215  Childhood absence epilepsy"
			},
			{
				"name":"H02217  Juvenile myoclonic epilepsy"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H01890  Pattern dystrophies of the retinal pigment epithelium"
			},
			{
				"name":"H01180  Sveinsson chorioretinal atrophy (SCRA)"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H01868  Mitral valve prolapse"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00293  Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"H00669  Naxos disease"
			},
			{
				"name":"H00893  Dilated cardiomyopathy with woolly hair, keratoderma, and tooth agenesis"
			},
			{
				"name":"H02094  Carvajal syndrome"
			},
			{
				"name":"H00535  Lymphatic malformation"
			},
			{
				"name":"H02169  Hennekam lymphangiectasia-lymphedema syndrome"
			},
			{
				"name":"H02648  Acantholytic blistering of the oral and laryngeal mucosa"
			},
			{
				"name":"H00717  Striate palmoplantar keratoderma"
			},
			{
				"name":"H00784  Localized autosomal recessive hypotrichosis"
			},
			{
				"name":"H00782  Hypotrichosis and recurrent skin vesicles"
			},
			{
				"name":"H01307  Nonsyndromic congenital nail disorder"
			},
			{
				"name":"H00644  Ectodermal dysplasia\/skin fragility syndrome"
			},
			{
				"name":"H01737  Epidermolysis bullosa"
			},
			{
				"name":"H03009  Yellow nail syndrome"
			},
			{
				"name":"H01677  Congenital hydrocephalus"
			},
			{
				"name":"H01881  Complex cortical dysplasia with other brain malformations"
			},
			{
				"name":"H01114  Ocular coloboma"
			},
			{
				"name":"H00589  Familial exudative vitreoretinopathy"
			},
			{
				"name":"H02716  Becker nevus syndrome"
			},
			{
				"name":"H00485  Robinow syndrome"
			},
			{
				"name":"H02853  Teebi hypertelorism syndrome"
			},
			{
				"name":"H02456  Ectodermal dysplasia"
			},
			{
				"name":"H00639  Ectodermal dysplasia, ectrodactyly, and macular dystrophy"
			},
			{
				"name":"H02474  Blepharocheilodontic syndrome"
			},
			{
				"name":"H00785  Congenital hypotrichosis with juvenile macular dystrophy"
			},
			{
				"name":"H03008  Congenital erythroderma with palmoplantar keratoderma, hypotrichosis, and hyper-IgE"
			},
			{
				"name":"H00504  Rubinstein-Taybi syndrome"
			},
			{
				"name":"H01393  Van Maldergem syndrome"
			},
			{
				"name":"H02023  Baraitser-Winter syndrome"
			},
			{
				"name":"H02191  Noonan-like syndrome with loose anagen hair"
			},
			{
				"name":"H02508  Agenesis of corpus callosum, cardiac, ocular, and genital syndrome"
			},
			{
				"name":"H02650  Menke-Hennekam syndrome"
			},
			{
				"name":"H02926  Elsahy-Waters syndrome"
			},
			{
				"name":"H03042  Developmental delay, language impairment, and ocular abnormalities"
			},
			{
				"name":"H00779  Usher syndrome"
			},
			{
				"name":"H03010  Neurodevelopmental disorder with absent language and variable seizures"
			},
			{
				"name":"H03011  Congenital hypotonia, epilepsy, developmental delay, and digital anomalies"
			},
			{
				"name":"H03041  Neurodevelopmental disorder with poor growth and skeletal anomalies"
			},
			{
				"name":"H03043  Neurodevelopmental disorder with structural brain anomalies and dysmorphic facies"
			}
			]
		},
		{
			"name":"nt06512  Chromosome cohesion and segregation",
			"children":[
			{
				"name":"H00014  Non-small cell lung cancer"
			},
			{
				"name":"H00013  Small cell lung cancer"
			},
			{
				"name":"H01752  ATR-X syndrome"
			},
			{
				"name":"H02308  Immunodeficiency-centromeric instability-facial anomalies syndrome"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00591  Facioscapulohumeral muscular dystrophy"
			},
			{
				"name":"H02122  Chronic atrial and intestinal dysrhythmia"
			},
			{
				"name":"H01897  Oocyte\/zygote\/embryo maturation arrest"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H00267  Holoprosencephaly"
			},
			{
				"name":"H02707  Khan-Khan-Katsanis syndrome"
			},
			{
				"name":"H01734  Rothmund-Thomson syndrome"
			},
			{
				"name":"H00572  Roberts-SC phocomelia syndrome"
			},
			{
				"name":"H00631  Cornelia de Lange syndrome"
			},
			{
				"name":"H00914  Warsaw breakage syndrome"
			},
			{
				"name":"H02581  Juberg-Hayward syndrome"
			},
			{
				"name":"H02582  Mullegama-Klein-Martinez syndrome"
			},
			{
				"name":"H02583  X-linked intellectual disability-hypotonic facies syndrome"
			},
			{
				"name":"H02584  Ferguson-Bonni neurodevelopmental syndrome"
			},
			{
				"name":"H02632  Houge-Janssens syndrome"
			},
			{
				"name":"H02854  Okur-Chung neurodevelopmental syndrome"
			}
			]
		},
		{
			"name":"nt06515  Regulation of kinetochore-microtubule interactions",
			"children":[
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00024  Prostate cancer"
			},
			{
				"name":"H01740  Macrothrombocytopenia"
			},
			{
				"name":"H02585  Roifman-Chitayat syndrome"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H00879  Perry syndrome"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00455  Spinal muscular atrophy"
			},
			{
				"name":"H00856  Distal hereditary motor neuropathies"
			},
			{
				"name":"H02594  Congenital facial palsy with ptosis and velopharyngeal dysfunction"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00789  Keratoconus"
			},
			{
				"name":"H01880  Autosomal recessive microcephaly and chorioretinopathy"
			},
			{
				"name":"H00837  Leber congenital amaurosis"
			},
			{
				"name":"H00838  Congenital fibrosis of the extraocular muscles"
			},
			{
				"name":"H01897  Oocyte\/zygote\/embryo maturation arrest"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H01881  Complex cortical dysplasia with other brain malformations"
			},
			{
				"name":"H01870  Microhydranencephaly"
			},
			{
				"name":"H00268  Lissencephaly"
			},
			{
				"name":"H02606  Pachygyria, microcephaly, developmental delay, and dysmorphic facies, with or without seizures"
			},
			{
				"name":"H02157  Short-rib thoracic dysplasia"
			},
			{
				"name":"H01734  Rothmund-Thomson syndrome"
			},
			{
				"name":"H01814  Stromme syndrome"
			},
			{
				"name":"H02595  Oculoskeletodental syndrome"
			},
			{
				"name":"H02607  Short stature and microcephaly with genital anomalies"
			},
			{
				"name":"H01288  Mosaic variegated aneuploidy syndrome"
			},
			{
				"name":"H02584  Ferguson-Bonni neurodevelopmental syndrome"
			},
			{
				"name":"H02857  Neurodevelopmental disorder with microcephaly and structural brain anomalies"
			},
			{
				"name":"H01579  Congenital symmetric circumferential skin creases"
			}
			]
		},
		{
			"name":"nt06534  Unfolded protein response",
			"children":[
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00056  Alzheimer disease"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H00061  Prion disease"
			}
			]
		},
		{
			"name":"nt06532  Autophagy",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00150  Danon disease"
			},
			{
				"name":"H00833  Neurodegeneration with brain iron accumulation"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H00810  Progressive myoclonic epilepsy"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00265  Hereditary sensory and autonomic neuropathy"
			},
			{
				"name":"H00594  Distal myopathy"
			},
			{
				"name":"H00612  Primary open angle glaucoma"
			},
			{
				"name":"H01227  Inflammatory bowel disease (IBD)"
			},
			{
				"name":"H00437  Paget disease of bone"
			},
			{
				"name":"H01282  Spermatogenic failure"
			},
			{
				"name":"H00799  CEDNIK syndrome"
			},
			{
				"name":"H02861  Neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures"
			}
			]
		},
		{
			"name":"nt06536  Mitophagy",
			"children":[
			{
				"name":"H00469  Mitochondrial DNA depletion syndrome"
			},
			{
				"name":"H00658  X-linked syndromic intellectual developmental disorder"
			},
			{
				"name":"H01600  Parkinsonian syndrome"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00594  Distal myopathy"
			},
			{
				"name":"H01020  Optic atrophy"
			},
			{
				"name":"H00612  Primary open angle glaucoma"
			},
			{
				"name":"H00437  Paget disease of bone"
			}
			]
		},
		{
			"name":"nt06535  Efferocytosis",
			"children":[
			{
				"name":"H01605  Myelofibrosis"
			},
			{
				"name":"H00012  Polycythemia vera"
			},
			{
				"name":"H00003  Acute myeloid leukemia"
			},
			{
				"name":"H02664  Joint contracture, osteochondromas, and B-cell lymphoma"
			},
			{
				"name":"H00232  Hereditary stomatocytosis"
			},
			{
				"name":"H02658  X-linked congenital hemolytic anemia"
			},
			{
				"name":"H00236  Congenital polycythemia"
			},
			{
				"name":"H00223  Inherited thrombophilia"
			},
			{
				"name":"H01235  Bleeding disorder platelet-type"
			},
			{
				"name":"H01108  CD36 deficiency"
			},
			{
				"name":"H00226  Glanzmann thrombasthenia"
			},
			{
				"name":"H01162  Scott syndrome"
			},
			{
				"name":"H01612  Essential thrombocythemia"
			},
			{
				"name":"H00102  Classic complement pathway component defects"
			},
			{
				"name":"H02467  Neonatal inflammatory skin and bowel disease"
			},
			{
				"name":"H00084  Graft-versus-host disease"
			},
			{
				"name":"H02669  Inflammatory bowel disease, immunodeficiency, and encephalopathy"
			},
			{
				"name":"H01267  Familial hyperinsulinemic hypoglycemia"
			},
			{
				"name":"H00186  Hyperargininemia"
			},
			{
				"name":"H02086  Mitochondrial complex III deficiency"
			},
			{
				"name":"H01248  Monocarboxylate transporter 1 deficiency"
			},
			{
				"name":"H00148  Lysosomal acid lipase deficiency"
			},
			{
				"name":"H00836  GLUT1 deficiency syndrome"
			},
			{
				"name":"H00833  Neurodegeneration with brain iron accumulation"
			},
			{
				"name":"H00159  Tangier disease"
			},
			{
				"name":"H00930  Hypoalphalipoproteinemia"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H01204  Cerebellar ataxia, mental retardation (MR), and dysequilibrium syndrome (CAMRQ)"
			},
			{
				"name":"H00056  Alzheimer disease"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H00808  Idiopathic generalized epilepsies"
			},
			{
				"name":"H00593  Limb-girdle muscular dystrophy"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H02321  Early-onset myopathy, areflexia, respiratory distress, and dysphagia"
			},
			{
				"name":"H01965  Miyoshi muscular dystrophy"
			},
			{
				"name":"H00527  Retinitis pigmentosa"
			},
			{
				"name":"H00821  Age-related macular degeneration"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H02339  Auditory neuropathy"
			},
			{
				"name":"H01742  Coronary artery disease"
			},
			{
				"name":"H00079  Asthma"
			},
			{
				"name":"H01191  Asthma with nasal polyps and aspirin intolerance"
			},
			{
				"name":"H00218  Cystic fibrosis"
			},
			{
				"name":"H00715  Darier disease"
			},
			{
				"name":"H00755  Acrokeratosis verruciformis"
			},
			{
				"name":"H02665  Reticulate acropigmentation of Kitamura"
			},
			{
				"name":"H00750  Keratosis pilaris atrophicans"
			},
			{
				"name":"H00630  Rheumatoid arthritis"
			},
			{
				"name":"H01897  Oocyte\/zygote\/embryo maturation arrest"
			},
			{
				"name":"H02559  Microvascular complications of diabetes"
			},
			{
				"name":"H00434  Camurati-Engelmann disease"
			},
			{
				"name":"H00498  Gnathodiaphyseal dysplasia"
			},
			{
				"name":"H01018  Metachondromatosis"
			},
			{
				"name":"H02294  Tatton-Brown-Rahman syndrome"
			}
			]
		},
		{
			"name":"nt06550  Lysosome biogenesis",
			"children":[
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00917  Congenital dyserythropoietic anemia"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H02133  Vici syndrome"
			},
			{
				"name":"H03012  Autoinflammation and autoimmunity, systemic, with immune dysregulation"
			},
			{
				"name":"H00100  Neutropenic disorders"
			},
			{
				"name":"H01425  Lysosomal storage disease"
			},
			{
				"name":"H00149  Neuronal ceroid lipofuscinosis"
			},
			{
				"name":"H02275  Batten disease"
			},
			{
				"name":"H02276  Kufs disease"
			},
			{
				"name":"H00143  Mucolipidosis II"
			},
			{
				"name":"H02130  Mucolipidosis III"
			},
			{
				"name":"H02205  Mucopolysaccharidosis-plus syndrome"
			},
			{
				"name":"H02729  Ain-Naz type of dysostosis multiplex"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H02692  Usmani-Riazuddin syndrome"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H01891  Autosomal recessive spinocerebellar ataxias"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H00810  Progressive myoclonic epilepsy"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00527  Retinitis pigmentosa"
			},
			{
				"name":"H01656  Psoriasis"
			},
			{
				"name":"H00166  Hermansky-Pudlak syndrome"
			},
			{
				"name":"H00168  Oculocutaneous albinism"
			},
			{
				"name":"H03036  Childhood- or juvenile-onset osteoporosis with developmental delay"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H00270  Periventricular nodular heterotopia"
			},
			{
				"name":"H01105  Cranio-lenticulo-sutural dysplasia"
			},
			{
				"name":"H02708  Baralle-Macken syndrome"
			},
			{
				"name":"H00436  Osteopetrosis"
			},
			{
				"name":"H01572  Cole-Carpenter syndrome"
			},
			{
				"name":"H00712  KID\/HID syndrome"
			},
			{
				"name":"H00799  CEDNIK syndrome"
			},
			{
				"name":"H01222  Cowden syndrome"
			},
			{
				"name":"H03039  Short stature-micrognathia syndrome"
			},
			{
				"name":"H02220  MEDNIK syndrome"
			},
			{
				"name":"H03035  Halperin-Birk syndrome"
			},
			{
				"name":"H03038  Pettigrew syndrome"
			},
			{
				"name":"H03044  Neurodevelopmental disorder with structural brain abnormalities and craniofacial abnormalities"
			},
			{
				"name":"H03045  Neurodevelopmental disorder with parkinsonism or other movement abnormalities"
			}
			]
		},
		{
			"name":"nt06551  Lysosome",
			"children":[
			{
				"name":"H00342  Tuberculosis"
			},
			{
				"name":"H01196  Hypochromic microcytic anemia"
			},
			{
				"name":"H01940  Glycogen storage disease type II"
			},
			{
				"name":"H00119  Congenital disorders of glycosylation type II"
			},
			{
				"name":"H01425  Lysosomal storage disease"
			},
			{
				"name":"H00124  GM2 gangliosidoses"
			},
			{
				"name":"H00281  GM1 gangliosidosis"
			},
			{
				"name":"H02016  Tay-Sachs disease"
			},
			{
				"name":"H02017  Sandhoff disease"
			},
			{
				"name":"H00125  Fabry disease"
			},
			{
				"name":"H00127  Metachromatic leukodystrophy"
			},
			{
				"name":"H00272  Multiple sulfatase deficiency"
			},
			{
				"name":"H00126  Gaucher disease"
			},
			{
				"name":"H00136  Niemann-Pick disease type C"
			},
			{
				"name":"H00137  Niemann-Pick disease type A\/B"
			},
			{
				"name":"H00138  Farber lipogranulomatosis"
			},
			{
				"name":"H00148  Lysosomal acid lipase deficiency"
			},
			{
				"name":"H01239  Combined SAP deficiency"
			},
			{
				"name":"H00149  Neuronal ceroid lipofuscinosis"
			},
			{
				"name":"H02277  Santavuori-Haltia disease"
			},
			{
				"name":"H02279  Neuronal ceroid lipofuscinosis due to Cathepsin D deficiency"
			},
			{
				"name":"H00144  Mucolipidosis IV"
			},
			{
				"name":"H00139  alpha-Mannosidosis"
			},
			{
				"name":"H00140  beta-Mannosidosis"
			},
			{
				"name":"H00141  Fucosidosis"
			},
			{
				"name":"H00142  Sialidosis"
			},
			{
				"name":"H00145  Aspartylglucosaminuria"
			},
			{
				"name":"H00276  Galactosialidosis"
			},
			{
				"name":"H00128  Mucopolysaccharidosis type I"
			},
			{
				"name":"H00129  Mucopolysaccharidosis type II"
			},
			{
				"name":"H00123  Mucopolysaccharidosis type IV"
			},
			{
				"name":"H00131  Mucopolysaccharidosis type VI"
			},
			{
				"name":"H00130  Mucopolysaccharidosis type III"
			},
			{
				"name":"H00132  Mucopolysaccharidosis type VII"
			},
			{
				"name":"H00133  Mucopolysaccharidosis type IX"
			},
			{
				"name":"H00147  Sialuria"
			},
			{
				"name":"H00273  Pycnodysostosis"
			},
			{
				"name":"H00275  Cystinosis"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00078  Frontotemporal lobar degeneration"
			},
			{
				"name":"H00135  Krabbe disease"
			},
			{
				"name":"H02696  Early-onset epilepsy"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00877  Brain small vessel disease"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H02802  Childhood-onset striatonigral degeneration"
			},
			{
				"name":"H00957  Corneal fleck dystrophy"
			},
			{
				"name":"H02822  Lisch epithelial corneal dystrophy"
			},
			{
				"name":"H00527  Retinitis pigmentosa"
			},
			{
				"name":"H01770  Macular dystrophy"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00557  Cutis laxa"
			},
			{
				"name":"H00428  Distal renal tubular acidosis"
			},
			{
				"name":"H00271  Polymicrogyria"
			},
			{
				"name":"H00436  Osteopetrosis"
			},
			{
				"name":"H02127  Yunis-Varon syndrome"
			},
			{
				"name":"H02058  Kohlschutter-Tonz syndrome"
			},
			{
				"name":"H02219  DDOD syndrome"
			},
			{
				"name":"H02417  Gingival fibromatosis with hypertrichosis"
			},
			{
				"name":"H00815  H syndrome"
			},
			{
				"name":"H01573  Zimmermann-Laband syndrome"
			},
			{
				"name":"H03034  Hypopigmentation, organomegaly, and delayed myelination and development"
			},
			{
				"name":"H03040  Neurodevelopmental disorder with epilepsy and brain atrophy"
			},
			{
				"name":"H03046  Intellectual developmental disorder with poor growth and with or without seizures or ataxia"
			}
			]
		},
		{
			"name":"nt06524  Apoptosis",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00278  Enteropathogenic Escherichia coli (EPEC) infection"
			},
			{
				"name":"H00277  Enterohemorrhagic Escherichia coli (EHEC) infection"
			},
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H00398  Influenza"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H00020  Colorectal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00013  Small cell lung cancer"
			},
			{
				"name":"H00030  Cervical cancer"
			},
			{
				"name":"H02610  Head and neck squamous cell carcinoma"
			},
			{
				"name":"H00978  Thrombocytopenia (THC)"
			},
			{
				"name":"H00108  Autoimmune lymphoproliferative syndromes"
			}
			]
		},
		{
			"name":"nt06525  Ferroptosis",
			"children":[
			{
				"name":"H01145  Atransferrinemia"
			},
			{
				"name":"H01196  Hypochromic microcytic anemia"
			},
			{
				"name":"H02206  Aceruloplasminemia"
			},
			{
				"name":"H00668  Anemia due to disorders of glutathione metabolism"
			},
			{
				"name":"H02312  Glutathione synthetase deficiency"
			},
			{
				"name":"H00833  Neurodegeneration with brain iron accumulation"
			},
			{
				"name":"H00211  Hemochromatosis"
			},
			{
				"name":"H01938  Hypermanganesemia with dystonia"
			},
			{
				"name":"H00480  X-linked intellectual developmental disorder"
			},
			{
				"name":"H01825  Spondylometaphyseal dysplasia, Sedaghatian type"
			}
			]
		},
		{
			"name":"nt06527  Necroptosis",
			"children":[
			{
				"name":"H02536  Infection-induced acute encephalopathy"
			},
			{
				"name":"H02610  Head and neck squamous cell carcinoma"
			},
			{
				"name":"H00827  Brooke-Spiegler syndrome"
			},
			{
				"name":"H00828  Familial cylindromatosis"
			},
			{
				"name":"H00829  Multiple familial trichoepithelioma"
			},
			{
				"name":"H02525  Disorders of innate immunity"
			},
			{
				"name":"H02620  Autoinflammation with episodic fever and lymphadenopathy"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H00108  Autoimmune lymphoproliferative syndromes"
			},
			{
				"name":"H01969  X-linked lymphoproliferative syndrome"
			},
			{
				"name":"H00912  Tumor necrosis factor receptor-associated periodic syndrome"
			},
			{
				"name":"H01490  Multiple sclerosis"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00821  Age-related macular degeneration"
			}
			]
		},
		{
			"name":"nt06529  Thermogenesis",
			"children":[
			{
				"name":"H02106  Genetic obesity"
			},
			{
				"name":"H01369  ATP synthase deficiency"
			},
			{
				"name":"H00473  Mitochondrial complex I deficiency"
			},
			{
				"name":"H01368  Cytochrome c oxidase (COX) deficiency"
			},
			{
				"name":"H02005  Mitochondrial complex II deficiency"
			},
			{
				"name":"H02086  Mitochondrial complex III deficiency"
			}
			]
		},
		{
			"name":"nt06539  Cytoskeleton in muscle cells",
			"children":[
			{
				"name":"H01133  Reynolds syndrome"
			},
			{
				"name":"H00234  Pelger-Huet anomaly"
			},
			{
				"name":"H00420  Familial partial lipodystrophy"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H01255  Juvenile-onset dystonia"
			},
			{
				"name":"H01230  LMNB1-related autosomal dominant leukodystrophy"
			},
			{
				"name":"H00810  Progressive myoclonic epilepsy"
			},
			{
				"name":"H00877  Brain small vessel disease"
			},
			{
				"name":"H02718  Autosomal dominant pontine microangiopathy and leukoencephalopathy"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H00798  Familial carpal tunnel syndrome"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00770  Congenital myasthenic syndrome"
			},
			{
				"name":"H00562  Dystrophinopathies"
			},
			{
				"name":"H00563  Emery-Dreifuss muscular dystrophy"
			},
			{
				"name":"H00593  Limb-girdle muscular dystrophy"
			},
			{
				"name":"H00656  Scapuloperoneal myopathy"
			},
			{
				"name":"H00590  Congenital muscular dystrophies (CMD\/MDC)"
			},
			{
				"name":"H01341  Collagen VI myopathy"
			},
			{
				"name":"H01958  Merosin-deficient congenital muscular dystrophy"
			},
			{
				"name":"H02307  Muscular dystrophy-dystroglycanopathy"
			},
			{
				"name":"H00697  X-linked myopathy with postural muscle atrophy"
			},
			{
				"name":"H02721  Scapulohumeroperoneal myopathy"
			},
			{
				"name":"H01777  Schwartz-Jampel syndrome"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H00698  Nemaline myopathy"
			},
			{
				"name":"H00657  Reducing body myopathy"
			},
			{
				"name":"H00594  Distal myopathy"
			},
			{
				"name":"H00595  Myofibrillar myopathies"
			},
			{
				"name":"H00958  Congenital stromal corneal dystrophy"
			},
			{
				"name":"H00805  Vitreoretinal degeneration"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H01209  Deafness, X-linked"
			},
			{
				"name":"H02339  Auditory neuropathy"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00292  Hypertrophic cardiomyopathy"
			},
			{
				"name":"H01219  Restrictive cardiomyopathy"
			},
			{
				"name":"H00293  Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"H00669  Naxos disease"
			},
			{
				"name":"H02094  Carvajal syndrome"
			},
			{
				"name":"H01216  Left ventricular noncompaction"
			},
			{
				"name":"H00729  Sick sinus syndrome"
			},
			{
				"name":"H00731  Atrial fibrillation"
			},
			{
				"name":"H02719  Multifocal fibromuscular dysplasia"
			},
			{
				"name":"H00801  Familial thoracic aortic aneurysm and dissection"
			},
			{
				"name":"H02553  Visceral myopathy"
			},
			{
				"name":"H00717  Striate palmoplantar keratoderma"
			},
			{
				"name":"H00584  Epidermolysis bullosa simplex"
			},
			{
				"name":"H00586  Epidermolysis bullosa, junctional"
			},
			{
				"name":"H01737  Epidermolysis bullosa"
			},
			{
				"name":"H00557  Cutis laxa"
			},
			{
				"name":"H00663  Restrictive dermopathy"
			},
			{
				"name":"H01173  Stiff skin syndrome"
			},
			{
				"name":"H02539  Intervertebral disc disease"
			},
			{
				"name":"H01593  Osteoporosis"
			},
			{
				"name":"H00582  Benign familial hematuria"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H00271  Polymicrogyria"
			},
			{
				"name":"H00553  Congenital supravalvular aortic stenosis"
			},
			{
				"name":"H00546  Atrial septal defect"
			},
			{
				"name":"H00459  Synpolydactyly"
			},
			{
				"name":"H02716  Becker nevus syndrome"
			},
			{
				"name":"H00673  Weill-Marchesani syndrome"
			},
			{
				"name":"H00579  Hereditary angiopathy with nephropathy, aneurysms, and muscle cramps (HANAC)"
			},
			{
				"name":"H00613  Infantile cortical hyperostosis"
			},
			{
				"name":"H02079  Oto-spondylo-megaepiphyseal dysplasia"
			},
			{
				"name":"H02080  Fibrochondrogenesis"
			},
			{
				"name":"H02155  Dyssegmental dysplasia"
			},
			{
				"name":"H02187  Spondyloepimetaphyseal dysplasia"
			},
			{
				"name":"H02185  Spondylometaphyseal dysplasia"
			},
			{
				"name":"H02732  Rhizomelic skeletal dysplasia with or without Pelger-Huet anomaly"
			},
			{
				"name":"H00477  Pseudoachondroplasia"
			},
			{
				"name":"H00476  Multiple epiphyseal dysplasia"
			},
			{
				"name":"H00900  Geleophysic dysplasia"
			},
			{
				"name":"H02228  Acromicric dysplasia"
			},
			{
				"name":"H00506  Osteogenesis imperfecta"
			},
			{
				"name":"H02299  Arthrogryposis multiplex congenita"
			},
			{
				"name":"H00811  Distal arthrogryposis"
			},
			{
				"name":"H00865  Lethal congenital contractural syndrome"
			},
			{
				"name":"H02717  Contractures, pterygia, and spondylocarpotarsal fusion syndrome"
			},
			{
				"name":"H02081  Marshall syndrome"
			},
			{
				"name":"H00665  Mandibuloacral dysplasia"
			},
			{
				"name":"H00653  Marfan syndrome"
			},
			{
				"name":"H02720  Meester-Loeys syndrome"
			},
			{
				"name":"H00802  Ehlers-Danlos syndrome"
			},
			{
				"name":"H02241  Ehlers-Danlos syndrome cardiac valvular type"
			},
			{
				"name":"H02242  Ehlers-Danlos syndrome vascular type"
			},
			{
				"name":"H02243  Ehlers-Danlos syndrome arthrochalasia type"
			},
			{
				"name":"H02724  Combined osteogenesis imperfecta and Ehlers-Danlos syndrome"
			},
			{
				"name":"H00601  Hutchinson-Gilford progeria syndrome"
			},
			{
				"name":"H01869  Megacystis microcolon intestinal hypoperistalsis syndrome"
			},
			{
				"name":"H02023  Baraitser-Winter syndrome"
			},
			{
				"name":"H02072  Stickler syndrome"
			},
			{
				"name":"H02725  Heart-hand syndrome"
			},
			{
				"name":"H02953  Uruguay facio-cardio-musculo-skeletal syndrome"
			},
			{
				"name":"H00581  Alport syndrome"
			},
			{
				"name":"H01260  Glomerulopathy with fibronectin deposits"
			}
			]
		},
		{
			"name":"nt06541  Cytoskeleton in neurons",
			"children":[
			{
				"name":"H01025  Familial adenomatous polyposis"
			},
			{
				"name":"H00917  Congenital dyserythropoietic anemia"
			},
			{
				"name":"H00233  MYH9-related disease"
			},
			{
				"name":"H01740  Macrothrombocytopenia"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H00624  Progressive familial intrahepatic cholestasis"
			},
			{
				"name":"H00768  Autosomal recessive intellectual developmental disorder"
			},
			{
				"name":"H00773  Autosomal dominant intellectual developmental disorder"
			},
			{
				"name":"H00077  Progressive supranuclear palsy"
			},
			{
				"name":"H00879  Perry syndrome"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H01255  Juvenile-onset dystonia"
			},
			{
				"name":"H02819  Neonatal intractable myoclonus"
			},
			{
				"name":"H01287  Congenital mirror movements"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H00606  Early infantile epileptic encephalopathy"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H01351  Spastic ataxia"
			},
			{
				"name":"H02114  Spastic paraplegia, optic atrophy, and neuropathy"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H00455  Spinal muscular atrophy"
			},
			{
				"name":"H00856  Distal hereditary motor neuropathies"
			},
			{
				"name":"H02594  Congenital facial palsy with ptosis and velopharyngeal dysfunction"
			},
			{
				"name":"H00264  Charcot-Marie-Tooth disease"
			},
			{
				"name":"H00265  Hereditary sensory and autonomic neuropathy"
			},
			{
				"name":"H01259  Giant axonal neuropathy"
			},
			{
				"name":"H01810  Congenital myopathy"
			},
			{
				"name":"H01097  Spastic quadriplegic cerebral palsy"
			},
			{
				"name":"H00789  Keratoconus"
			},
			{
				"name":"H01768  Central areolar choroidal dystrophy"
			},
			{
				"name":"H00527  Retinitis pigmentosa"
			},
			{
				"name":"H00814  Vitelliform macular dystrophy"
			},
			{
				"name":"H00837  Leber congenital amaurosis"
			},
			{
				"name":"H01890  Pattern dystrophies of the retinal pigment epithelium"
			},
			{
				"name":"H02513  Oculopharyngodistal myopathy"
			},
			{
				"name":"H00838  Congenital fibrosis of the extraocular muscles"
			},
			{
				"name":"H02450  Horizontal gaze palsy with progressive scoliosis"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H00605  Deafness, autosomal recessive"
			},
			{
				"name":"H01633  High blood pressure"
			},
			{
				"name":"H02022  Griscelli syndrome"
			},
			{
				"name":"H00584  Epidermolysis bullosa simplex"
			},
			{
				"name":"H00627  Premature ovarian failure"
			},
			{
				"name":"H01897  Oocyte\/zygote\/embryo maturation arrest"
			},
			{
				"name":"H01174  Congenital diarrhea"
			},
			{
				"name":"H00269  Primary microcephaly"
			},
			{
				"name":"H01881  Complex cortical dysplasia with other brain malformations"
			},
			{
				"name":"H00270  Periventricular nodular heterotopia"
			},
			{
				"name":"H01870  Microhydranencephaly"
			},
			{
				"name":"H02716  Becker nevus syndrome"
			},
			{
				"name":"H00897  Pontocerebellar hypoplasia"
			},
			{
				"name":"H00268  Lissencephaly"
			},
			{
				"name":"H02157  Short-rib thoracic dysplasia"
			},
			{
				"name":"H02873  Kyphomelic dysplasia"
			},
			{
				"name":"H00458  Syndromic craniosynostoses"
			},
			{
				"name":"H02023  Baraitser-Winter syndrome"
			},
			{
				"name":"H02663  Braddock-Carey syndrome"
			},
			{
				"name":"H00465  Fragile X syndrome"
			},
			{
				"name":"H01731  Fragile X tremor\/ataxia syndrome"
			},
			{
				"name":"H02688  Dworschak-Punetha neurodevelopmental syndrome"
			},
			{
				"name":"H02857  Neurodevelopmental disorder with microcephaly and structural brain anomalies"
			},
			{
				"name":"H02862  Neurodevelopmental disorder with or without variable brain abnormalities"
			},
			{
				"name":"H02863  Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter"
			},
			{
				"name":"H02864  Neurodevelopmental disorder with or without autism or seizures"
			},
			{
				"name":"H03026  Neurodevelopmental disorder with hypotonia, epilepsy, and absent speech"
			},
			{
				"name":"H03027  Neurodevelopmental disorder with speech delay, movement abnormalities, and seizures"
			},
			{
				"name":"H03028  Intellectual development disorder with seizures and dysmorphic facies"
			},
			{
				"name":"H03077  Developmental delay, impaired speech, and behavioral abnormalities"
			},
			{
				"name":"H01579  Congenital symmetric circumferential skin creases"
			}
			]
		},
		{
			"name":"nt06545  Cornified envelope formation",
			"children":[
			{
				"name":"H00171  Histidinemia"
			},
			{
				"name":"H00736  Dorfman-Chanarin syndrome"
			},
			{
				"name":"H00126  Gaucher disease"
			},
			{
				"name":"H00063  Spinocerebellar ataxia (SCA)"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H00058  Amyotrophic lateral sclerosis (ALS)"
			},
			{
				"name":"H00265  Hereditary sensory and autonomic neuropathy"
			},
			{
				"name":"H00819  Stargardt disease"
			},
			{
				"name":"H00294  Dilated cardiomyopathy"
			},
			{
				"name":"H00293  Arrhythmogenic right ventricular cardiomyopathy"
			},
			{
				"name":"H00669  Naxos disease"
			},
			{
				"name":"H02094  Carvajal syndrome"
			},
			{
				"name":"H02648  Acantholytic blistering of the oral and laryngeal mucosa"
			},
			{
				"name":"H01358  Atopic dermatitis"
			},
			{
				"name":"H00735  Ichthyosis vulgaris"
			},
			{
				"name":"H00733  Harlequin ichthyosis"
			},
			{
				"name":"H00734  Autosomal recessive congenital ichthyosis"
			},
			{
				"name":"H00691  Bullous congenital ichthyosiform erythroderma (BCIE)"
			},
			{
				"name":"H00693  Ichthyosis bullosa of Siemens"
			},
			{
				"name":"H00707  Ichthyosis hystrix"
			},
			{
				"name":"H02265  Annular epidermolytic ichthyosis"
			},
			{
				"name":"H00710  Erythrokeratodermia variabilis"
			},
			{
				"name":"H00738  Ichthyosis with confetti"
			},
			{
				"name":"H02449  Autosomal dominant lamellar ichthyosis"
			},
			{
				"name":"H00737  Peeling skin syndrome"
			},
			{
				"name":"H00714  Vohwinkel syndrome"
			},
			{
				"name":"H00722  Epidermolytic palmoplantar keratoderma"
			},
			{
				"name":"H00717  Striate palmoplantar keratoderma"
			},
			{
				"name":"H01796  Uncombable hair syndrome"
			},
			{
				"name":"H00784  Localized autosomal recessive hypotrichosis"
			},
			{
				"name":"H00644  Ectodermal dysplasia\/skin fragility syndrome"
			},
			{
				"name":"H00739  Ichthyosis with hypotrichosis"
			},
			{
				"name":"H00741  Ichthyosis prematurity syndrome"
			},
			{
				"name":"H02675  Ichthyotic keratoderma, spasticity, hypomyelination, and dysmorphic facial features"
			},
			{
				"name":"H02935  Ichthyosis, spastic quadriplegia, and impaired intellectual development"
			}
			]
		},
		{
			"name":"nt06552  Integrated stress response (ISR) signaling pathway",
			"children":[
			{
				"name":"H00982  Sideroblastic anemia"
			},
			{
				"name":"H00766  Wolcott-Rallison syndrome"
			},
			{
				"name":"H00057  Parkinson disease"
			},
			{
				"name":"H00831  Primary dystonia"
			},
			{
				"name":"H00679  Hypomyelinating leukodystrophy"
			},
			{
				"name":"H00869  Leukoencephalopathy with vanishing white matter"
			},
			{
				"name":"H02457  Developmental delay, leukoencephalopathy, and neurologic decompensation"
			},
			{
				"name":"H00266  Hereditary spastic paraplegia"
			},
			{
				"name":"H02342  Frontotemporal dementia and amyotrophic lateral sclerosis"
			},
			{
				"name":"H03051  Autosomal dominant isolated mitochondrial myopathy"
			},
			{
				"name":"H01866  Pulmonary veno-occlusive disease"
			},
			{
				"name":"H02195  MEHMO syndrome"
			},
			{
				"name":"H01923  Microcephaly, short stature, and impaired glucose metabolism"
			},
			{
				"name":"H01824  CODAS syndrome"
			},
			{
				"name":"H02343  EVEN-plus syndrome"
			}
			]
		}
		]
	},
	{
		"name":"Immune system",
		"children":[
		{
			"name":"nt06513  Complement cascade",
			"children":[
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H01434  Atypical hemolytic uremic syndrome"
			},
			{
				"name":"H00104  Alternative complement pathway component defects"
			},
			{
				"name":"H00102  Classic complement pathway component defects"
			},
			{
				"name":"H00103  Late complement pathway defects"
			},
			{
				"name":"H00105  Mannose-binding lectin pathway component defects"
			},
			{
				"name":"H00106  Complement regulatory protein defects"
			},
			{
				"name":"H02108  Basal laminar drusen"
			},
			{
				"name":"H00821  Age-related macular degeneration"
			},
			{
				"name":"H02240  Ehlers-Danlos syndrome periodontal type"
			},
			{
				"name":"H01887  3MC syndrome"
			},
			{
				"name":"H02579  C3 glomerulopathy"
			},
			{
				"name":"H02398  COVID-19"
			}
			]
		},
		{
			"name":"nt06514  Coagulation cascade",
			"children":[
			{
				"name":"H00219  Hemophilia"
			},
			{
				"name":"H02092  von Willebrand disease"
			},
			{
				"name":"H00938  Factor XI deficiency"
			},
			{
				"name":"H01254  Congenital prothrombin deficiency"
			},
			{
				"name":"H00222  Congenital fibrinogen deficiency"
			},
			{
				"name":"H02257  Factor X deficiency"
			},
			{
				"name":"H02256  Factor VII deficiency"
			},
			{
				"name":"H00220  Factor V deficiency"
			},
			{
				"name":"H00945  Factor XIII deficiency"
			},
			{
				"name":"H00941  Factor XII deficiency"
			},
			{
				"name":"H01078  Fletcher factor deficiency"
			},
			{
				"name":"H00983  Alpha-2-plasmin inhibitor (a2-PI) deficiency"
			},
			{
				"name":"H01106  Plasminogen activator inhibitor type 1 deficiency"
			},
			{
				"name":"H01206  Plasminogen deficiency"
			},
			{
				"name":"H00223  Inherited thrombophilia"
			},
			{
				"name":"H01381  Antithrombin III deficiency"
			},
			{
				"name":"H01235  Bleeding disorder platelet-type"
			},
			{
				"name":"H02093  Platelet-type von Willebrand disease"
			},
			{
				"name":"H01740  Macrothrombocytopenia"
			},
			{
				"name":"H00225  Thrombotic thrombocytopenic purpura"
			},
			{
				"name":"H01006  Hereditary angioedema"
			},
			{
				"name":"H00106  Complement regulatory protein defects"
			},
			{
				"name":"H01103  Alpha-1-antitrypsin deficiency"
			},
			{
				"name":"H00845  Familial amyloidosis"
			},
			{
				"name":"H01730  Myocardial infarction"
			},
			{
				"name":"H01714  Chronic obstructive pulmonary disease (COPD)"
			},
			{
				"name":"H01433  Budd-Chiari syndrome"
			}
			]
		},
		{
			"name":"nt06517  TLR signaling",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00278  Enteropathogenic Escherichia coli (EPEC) infection"
			},
			{
				"name":"H00277  Enterohemorrhagic Escherichia coli (EHEC) infection"
			},
			{
				"name":"H00298  Yersiniosis"
			},
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H00342  Tuberculosis"
			},
			{
				"name":"H00344  Leprosy"
			},
			{
				"name":"H00297  Plague"
			},
			{
				"name":"H00311  Legionellosis"
			},
			{
				"name":"H00317  Melioidosis"
			},
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H02536  Infection-induced acute encephalopathy"
			},
			{
				"name":"H00398  Influenza"
			},
			{
				"name":"H00394  Measles"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H00030  Cervical cancer"
			},
			{
				"name":"H00096  Defects of toll-like receptor signaling"
			},
			{
				"name":"H00080  Systemic lupus erythematosus"
			},
			{
				"name":"H00821  Age-related macular degeneration"
			},
			{
				"name":"H01227  Inflammatory bowel disease (IBD)"
			},
			{
				"name":"H02398  COVID-19"
			}
			]
		},
		{
			"name":"nt06521  NLR signaling",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00278  Enteropathogenic Escherichia coli (EPEC) infection"
			},
			{
				"name":"H00277  Enterohemorrhagic Escherichia coli (EHEC) infection"
			},
			{
				"name":"H00298  Yersiniosis"
			},
			{
				"name":"H00113  Salmonellosis"
			},
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H00297  Plague"
			},
			{
				"name":"H00398  Influenza"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H03012  Autoinflammation and autoimmunity, systemic, with immune dysregulation"
			},
			{
				"name":"H02588  NLRP1-associated autoinflammation with arthritis and dyskeratosis"
			},
			{
				"name":"H00288  Familial Mediterranean fever"
			},
			{
				"name":"H02159  Familial cold autoinflammatory syndrome"
			},
			{
				"name":"H02555  Muckle-Wells syndrome"
			},
			{
				"name":"H02556  CINCA syndrome"
			},
			{
				"name":"H00285  Blau syndrome"
			},
			{
				"name":"H00287  Pyogenic sterile arthritis, pyoderma gangrenosum, and acne syndrome"
			},
			{
				"name":"H01748  NLRC4 inflammasomopathy"
			},
			{
				"name":"H00604  Deafness, autosomal dominant"
			},
			{
				"name":"H01227  Inflammatory bowel disease (IBD)"
			},
			{
				"name":"H02590  Acute febrile neutrophilic dermatosis"
			},
			{
				"name":"H01372  Vitiligo"
			}
			]
		},
		{
			"name":"nt06519  RLR signaling",
			"children":[
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H02536  Infection-induced acute encephalopathy"
			},
			{
				"name":"H00398  Influenza"
			},
			{
				"name":"H00394  Measles"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H00048  Hepatocellular carcinoma"
			},
			{
				"name":"H02525  Disorders of innate immunity"
			},
			{
				"name":"H00290  Aicardi-Goutieres syndrome"
			},
			{
				"name":"H00880  Dyschromatosis symmetrica hereditaria"
			},
			{
				"name":"H01571  Singleton-Merten syndrome"
			},
			{
				"name":"H01806  Tenorio syndrome"
			},
			{
				"name":"H02398  COVID-19"
			}
			]
		},
		{
			"name":"nt06520  CGAS-STING signaling",
			"children":[
			{
				"name":"H00299  Shigellosis"
			},
			{
				"name":"H00365  Herpes simplex virus infection"
			},
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H02608  Autoinflammatory-pancytopenia syndrome"
			},
			{
				"name":"H00080  Systemic lupus erythematosus"
			},
			{
				"name":"H00290  Aicardi-Goutieres syndrome"
			},
			{
				"name":"H01000  Retinal vasculopathy with cerebral leukodystrophy"
			},
			{
				"name":"H00291  Familial chilblain lupus (FCL)"
			},
			{
				"name":"H01746  STING-associated vasculopathy with onset in infancy"
			}
			]
		},
		{
			"name":"nt06537  TCR\/BCR signaling",
			"children":[
			{
				"name":"H00298  Yersiniosis"
			},
			{
				"name":"H00297  Plague"
			},
			{
				"name":"H00394  Measles"
			},
			{
				"name":"H00008  Burkitt lymphoma"
			},
			{
				"name":"H00009  Adult T-cell leukemia"
			},
			{
				"name":"H00007  Hodgkin lymphoma"
			},
			{
				"name":"H00054  Nasopharyngeal cancer"
			},
			{
				"name":"H01725  Primary immunodeficiency disease"
			},
			{
				"name":"H02526  Disorders of adaptive immunity"
			},
			{
				"name":"H00085  Agammaglobulinemias"
			},
			{
				"name":"H00088  Common variable immunodeficiency"
			},
			{
				"name":"H00093  Combined immunodeficiency"
			},
			{
				"name":"H00091  T-B+Severe combined immunodeficiency"
			},
			{
				"name":"H01387  Activated PI3K-delta syndrome"
			},
			{
				"name":"H02585  Roifman-Chitayat syndrome"
			},
			{
				"name":"H00108  Autoimmune lymphoproliferative syndromes"
			},
			{
				"name":"H00080  Systemic lupus erythematosus"
			},
			{
				"name":"H02540  Infantile-onset multisystem autoimmune disease"
			},
			{
				"name":"H02159  Familial cold autoinflammatory syndrome"
			},
			{
				"name":"H01743  Autoinflammation and PLCG2-associated antibody deficiency and immune dysregulation"
			},
			{
				"name":"H00081  Hashimoto thyroiditis"
			},
			{
				"name":"H00254  Growth hormone deficiency"
			},
			{
				"name":"H01370  SHORT syndrome"
			}
			]
		},
		{
			"name":"nt06533  Chemokine signaling",
			"children":[
			{
				"name":"H01563  HIV infection"
			},
			{
				"name":"H00368  Cytomegalovirus infection"
			},
			{
				"name":"H00041  Kaposi sarcoma"
			},
			{
				"name":"H00097  WHIM syndrome"
			},
			{
				"name":"H00100  Neutropenic disorders"
			}
			]
		}
		]
	},
	{
		"name":"Endocrine system",
		"children":[
		{
			"name":"nt06310  CRH-ACTH-cortisol signaling",
			"children":[
			{
				"name":"H01102  Pituitary adenomas"
			},
			{
				"name":"H01431  Cushing syndrome"
			},
			{
				"name":"H00260  Pigmented micronodular adrenocortical disease"
			},
			{
				"name":"H02049  Bilateral macronodular adrenal hyperplasia"
			},
			{
				"name":"H01702  Glucocorticoid resistance syndrome"
			},
			{
				"name":"H00602  Glucocorticoid-remediable aldosteronism (GRA)"
			},
			{
				"name":"H00256  Familial glucocorticoid deficiency"
			},
			{
				"name":"H02316  Adrenal insufficiency, NR5A1 related"
			},
			{
				"name":"H01772  Adrenal hypoplasia, congenital"
			}
			]
		},
		{
			"name":"nt06322  TRH-TSH-TH signaling",
			"children":[
			{
				"name":"H00251  Thyroid dyshormonogenesis"
			},
			{
				"name":"H00249  Thyroid hormone resistance syndrome"
			},
			{
				"name":"H00250  Congenital nongoitrous hypothyroidism (CHNG)"
			},
			{
				"name":"H00650  Allan-Herndon-Dudley syndrome"
			},
			{
				"name":"H01269  Congenital hyperthyroidism"
			}
			]
		},
		{
			"name":"nt06323  KISS1-GnRH-LH\/FSH-E2 signaling",
			"children":[
			{
				"name":"H01253  Isolated follicle-stimulating hormone deficiency"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H02061  Estrogen resistance syndrome"
			},
			{
				"name":"H00937  Precocious puberty"
			}
			]
		},
		{
			"name":"nt06324  GHRH-GH-IGF signaling",
			"children":[
			{
				"name":"H01483  Acromegaly"
			},
			{
				"name":"H01274  Growth delay due to insulin-like growth factor I resistance"
			},
			{
				"name":"H02035  Isolated growth hormone deficiency"
			},
			{
				"name":"H02036  Combined pituitary hormone deficiency"
			},
			{
				"name":"H02037  Laron syndrome"
			},
			{
				"name":"H02040  Insulin-like growth factor I deficiency"
			},
			{
				"name":"H00254  Growth hormone deficiency"
			},
			{
				"name":"H02106  Genetic obesity"
			}
			]
		},
		{
			"name":"nt06318  CaSR-PTH signaling",
			"children":[
			{
				"name":"H01862  Hypoparathyroidism"
			},
			{
				"name":"H00244  Pseudohypoparathyroidism"
			},
			{
				"name":"H00246  Primary hyperparathyroidism"
			},
			{
				"name":"H02030  Neonatal hyperparathyroidism"
			}
			]
		},
		{
			"name":"nt06316  Renin-angiotensin-aldosterone signaling",
			"children":[
			{
				"name":"H01603  Primary aldosteronism"
			},
			{
				"name":"H00575  Renal tubular dysgenesis"
			}
			]
		},
		{
			"name":"nt06325  Hormone\/cytokine signaling",
			"children":[
			{
				"name":"H00250  Congenital nongoitrous hypothyroidism (CHNG)"
			},
			{
				"name":"H00408  Type 1 diabetes mellitus"
			},
			{
				"name":"H00410  Maturity onset diabetes of the young (MODY)"
			},
			{
				"name":"H01228  Insulin-resistant diabetes mellitus with acanthosis nigricans"
			},
			{
				"name":"H00719  Leprechaunism"
			},
			{
				"name":"H00942  Rabson-Mendenhall syndrome"
			},
			{
				"name":"H01267  Familial hyperinsulinemic hypoglycemia"
			},
			{
				"name":"H01388  Hyperprolactinemia"
			},
			{
				"name":"H01294  Nephrogenic syndrome of inappropriate antidiuresis"
			},
			{
				"name":"H00255  Hypogonadotropic hypogonadism"
			},
			{
				"name":"H00253  Neurohypophyseal diabetes insipidus"
			},
			{
				"name":"H02059  Leptin deficiency"
			},
			{
				"name":"H02060  Leptin receptor deficiency"
			},
			{
				"name":"H01193  Familial tumoral calcinosis"
			},
			{
				"name":"H00967  Adiponectin deficiency"
			},
			{
				"name":"H00214  Hypophosphatemic rickets"
			},
			{
				"name":"H00240  Gitelman syndrome"
			},
			{
				"name":"H01371  Hypercalcemia infantile"
			},
			{
				"name":"H01293  Narcolepsy"
			},
			{
				"name":"H00809  Familial epilepsy temporal lobe (ETL)"
			},
			{
				"name":"H00265  Hereditary sensory and autonomic neuropathy"
			},
			{
				"name":"H02674  Atrial standstill"
			},
			{
				"name":"H00731  Atrial fibrillation"
			},
			{
				"name":"H00801  Familial thoracic aortic aneurysm and dissection"
			},
			{
				"name":"H00759  Waardenburg syndrome"
			},
			{
				"name":"H01198  Fanconi renotubular syndrome"
			},
			{
				"name":"H00243  Renal tubular acidosis type 4"
			},
			{
				"name":"H00888  Nephrolithiasis\/osteoporosis, hypophosphatemic"
			},
			{
				"name":"H00512  Permanent neonatal diabetes mellitus"
			},
			{
				"name":"H00910  Hirschsprung disease"
			},
			{
				"name":"H02185  Spondylometaphyseal dysplasia"
			},
			{
				"name":"H02543  Acromesomelic dysplasia"
			},
			{
				"name":"H01884  Auriculocondylar syndrome"
			},
			{
				"name":"H02679  Miura-type epiphyseal chondrodysplasia"
			},
			{
				"name":"H02126  Mandibulofacial dysostosis with alopecia"
			},
			{
				"name":"H00823  ABCD syndrome"
			},
			{
				"name":"H02681  Short stature with nonspecific skeletal abnormalities"
			}
			]
		},
		{
			"name":"nt06320  APOB-LDLR signaling",
			"children":[
			{
				"name":"H01635  Hyperlipidemia"
			},
			{
				"name":"H00155  Familial hypercholesterolemia"
			},
			{
				"name":"H01918  Familial autosomal recessive hypercholesterolemia"
			}
			]
		}
		]
	}
	]
}