{
	"name":"cge03400",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"100767894 Mgmt; methylated-DNA--protein-cysteine methyltransferase isoform X2\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				},
				{
					"name":"100753724 Alkbh2; DNA oxidative demethylase ALKBH2\tK10859 ALKBH2; DNA oxidative demethylase [EC:1.14.11.33]"
				},
				{
					"name":"100774403 Alkbh3; alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 isoform X1\tK10860 ALKBH3; mRNA N1-methyladenine demethylase [EC:1.14.11.54]"
				},
				{
					"name":"100762460 Ascc3; activating signal cointegrator 1 complex subunit 3 isoform X1\tK18663 ASCC3; activating signal cointegrator complex subunit 3 [EC:5.6.2.4]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"100753421 Ung; uracil-DNA glycosylase isoform X2\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"100751971 Ccno; cyclin-O isoform X2\tK10861 UDG2; uracil-DNA glycosylase 2 [EC:3.2.2.-]"
					},
					{
						"name":"100752484 LOW QUALITY PROTEIN: G\/T mismatch-specific thymine DNA glycosylase isoform X2\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"100771878 LOW QUALITY PROTEIN: G\/T mismatch-specific thymine DNA glycosylase isoform X2\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"100772748 Tdg; G\/T mismatch-specific thymine DNA glycosylase isoform X2\tK20813 TDG; thymine-DNA glycosylase [EC:3.2.2.29]"
					},
					{
						"name":"100758892 Mpg; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"100770488 Smug1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"100752384 Mutyh; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"100772468 Mbd4; methyl-CpG-binding domain protein 4 isoform X1\tK10801 MBD4; methyl-CpG-binding domain protein 4 [EC:3.2.2.-]"
					},
					{
						"name":"100774353 Ogg1; N-glycosylase\/DNA lyase isoform X1\tK03660 OGG1; N-glycosylase\/DNA lyase [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100762109 Neil1; endonuclease 8-like 1 isoform X1\tK10567 NEIL1; endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100756411 Neil2; endonuclease 8-like 2\tK10568 NEIL2; endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100753722 Neil3; endonuclease 8-like 3 isoform X1\tK10569 NEIL3; endonuclease VIII-like 3 [EC:3.2.2.- 4.2.99.18]"
					},
					{
						"name":"100755553 Nthl1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases",
					"children":[
					{
						"name":"100689281 Apex1; DNA-(apurinic or apyrimidinic site) lyase\tK10771 APEX1; AP endonuclease 1 [EC:3.1.11.2]"
					},
					{
						"name":"100753797 Apex2; DNA-(apurinic or apyrimidinic site) endonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					},
					{
						"name":"100772896 DNA-(apurinic or apyrimidinic site) endonuclease 2\tK10772 APEX2; AP endonuclease 2 [EC:3.1.11.2]"
					}
					]
				},
				{
					"name":"Long Patch-BER factors",
					"children":[
					{
						"name":"DNA polymerase delta complex",
						"children":[
						{
							"name":"100773935 Pold1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"100762815 Pold2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
						},
						{
							"name":"100756090 Pold3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
						},
						{
							"name":"100761682 Pold4; DNA polymerase delta subunit 4 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4"
						}
						]
					},
					{
						"name":"DNA polymerase epsilon complex",
						"children":[
						{
							"name":"100774671 Pole; DNA polymerase epsilon catalytic subunit A isoform X2\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
						},
						{
							"name":"100754280 Pole2; DNA polymerase epsilon subunit 2 isoform X1\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
						},
						{
							"name":"100752018 Pole3; DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
						},
						{
							"name":"103163165 LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 4\tK03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
						}
						]
					},
					{
						"name":"100689335 Pcna; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100768360 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100756103 Fen1; flap endonuclease 1 isoform X2\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"100767365 Lig1; DNA ligase 1 isoform X2\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				},
				{
					"name":"Short Patch-BER factors",
					"children":[
					{
						"name":"100774965 Polb; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100689414 Xrcc1; DNA repair protein XRCC1\tK10803 XRCC1; DNA-repair protein XRCC1"
					},
					{
						"name":"100765011 Lig3; DNA ligase 3 isoform X1\tK10776 LIG3; DNA ligase 3 [EC:6.5.1.1]"
					}
					]
				},
				{
					"name":"Other BER factors",
					"children":[
					{
						"name":"100769476 Tdp1; tyrosyl-DNA phosphodiesterase 1\tK10862 TDP1; tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-]"
					},
					{
						"name":"100774231 Aptx; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"100765532 Aplf; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"100767996 Pnkp; bifunctional polynucleotide phosphatase\/kinase isoform X1\tK08073 PNKP; bifunctional polynucleotide phosphatase\/kinase [EC:3.1.3.32 2.7.1.78]"
					},
					{
						"name":"100751631 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100754755 Hmgb1; high mobility group protein B1 isoform X2\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100761755 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"113836333 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100751096 Poll; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100689463 Parp1; poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
					},
					{
						"name":"100753655 Parp2; poly [ADP-ribose] polymerase 2 isoform X1\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
					},
					{
						"name":"100764843 Parp3; protein mono-ADP-ribosyltransferase PARP3 isoform X1\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					},
					{
						"name":"100765231 Parp4; protein mono-ADP-ribosyltransferase PARP4 isoform X2\tK10798 PARP3_4; protein mono-ADP-ribosyltransferase 3\/4 [EC:2.4.2.-]"
					}
					]
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors",
					"children":[
					{
						"name":"XPC-HR23B-CETN2 complex",
						"children":[
						{
							"name":"100764712 Xpc; DNA repair protein complementing XP-C cells isoform X1\tK10838 XPC; xeroderma pigmentosum group C-complementing protein"
						},
						{
							"name":"100757595 Rad23a; UV excision repair protein RAD23 homolog A isoform X3\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"100763817 Rad23b; UV excision repair protein RAD23 homolog B isoform X2\tK10839 RAD23; UV excision repair protein RAD23"
						},
						{
							"name":"100753513 centrin-2-like\tK10840 CETN2; centrin-2"
						},
						{
							"name":"100768482 Cetn2; centrin-2 isoform X1\tK10840 CETN2; centrin-2"
						}
						]
					},
					{
						"name":"Cul4-DDB2 complex",
						"children":[
						{
							"name":"100762556 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"100760883 Cul4a; cullin-4A isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100763989 Cul4b; cullin-4B isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100767300 LOW QUALITY PROTEIN: cullin-4B-like isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100764133 Ddb1; DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"100756705 Ddb2; LOW QUALITY PROTEIN: DNA damage-binding protein 2\tK10140 DDB2; DNA damage-binding protein 2"
						}
						]
					},
					{
						"name":"NER4 complex"
					}
					]
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase II complex",
						"children":[
						{
							"name":"100689016 Polr2a; DNA-directed RNA polymerase II subunit RPB1\tK03006 RPB1; DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6]"
						},
						{
							"name":"100755901 Polr2b; DNA-directed RNA polymerase II subunit RPB2 isoform X2\tK03010 RPB2; DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6]"
						},
						{
							"name":"100765460 Polr2c; DNA-directed RNA polymerase II subunit RPB3 isoform X1\tK03011 RPB3; DNA-directed RNA polymerase II subunit RPB3"
						},
						{
							"name":"100755604 Polr2d; DNA-directed RNA polymerase II subunit RPB4 isoform X2\tK03012 RPB4; DNA-directed RNA polymerase II subunit RPB4"
						},
						{
							"name":"100754513 Polr2e; DNA-directed RNA polymerases I, II, and III subunit RPABC1 isoform X1\tK03013 RPABC1; DNA-directed RNA polymerases I, II, and III subunit RPABC1"
						},
						{
							"name":"100754156 Polr2f; DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X1\tK03014 RPABC2; DNA-directed RNA polymerases I, II, and III subunit RPABC2"
						},
						{
							"name":"100754072 Polr2g; DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"100765781 DNA-directed RNA polymerase II subunit RPB7\tK03015 RPB7; DNA-directed RNA polymerase II subunit RPB7"
						},
						{
							"name":"100769706 Polr2h; DNA-directed RNA polymerases I, II, and III subunit RPABC3\tK03016 RPABC3; DNA-directed RNA polymerases I, II, and III subunit RPABC3"
						},
						{
							"name":"113837369 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"113837639 DNA-directed RNA polymerase II subunit RPB9\tK03017 RPB9; DNA-directed RNA polymerase II subunit RPB9"
						},
						{
							"name":"100754830 Polr2l; DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100755123 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100761930 DNA-directed RNA polymerases I, II, and III subunit RPABC5\tK03007 RPABC5; DNA-directed RNA polymerases I, II, and III subunit RPABC5"
						},
						{
							"name":"100766101 DNA-directed RNA polymerase II subunit RPB11-a\tK03008 RPB11; DNA-directed RNA polymerase II subunit RPB11"
						},
						{
							"name":"100762645 Polr2k; DNA-directed RNA polymerases I, II, and III subunit RPABC4\tK03009 RPABC4; DNA-directed RNA polymerases I, II, and III subunit RPABC4"
						}
						]
					},
					{
						"name":"Cul4-CSA complex",
						"children":[
						{
							"name":"100762556 Rbx1; E3 ubiquitin-protein ligase RBX1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
						},
						{
							"name":"100760883 Cul4a; cullin-4A isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100763989 Cul4b; cullin-4B isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100767300 LOW QUALITY PROTEIN: cullin-4B-like isoform X2\tK10609 CUL4; cullin 4"
						},
						{
							"name":"100764133 Ddb1; DNA damage-binding protein 1 isoform X1\tK10610 DDB1; DNA damage-binding protein 1"
						},
						{
							"name":"100755229 Ercc8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
						}
						]
					},
					{
						"name":"Other TCR factor",
						"children":[
						{
							"name":"100770299 Ercc6; DNA excision repair protein ERCC-6 isoform X1\tK10841 ERCC6; DNA excision repair protein ERCC-6"
						},
						{
							"name":"100766412 Uvssa; UV-stimulated scaffold protein A isoform X3\tK23720 UVSSA; UV-stimulated scaffold protein A"
						},
						{
							"name":"100753010 Elof1; transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						},
						{
							"name":"100765103 transcription elongation factor 1 homolog\tK25829 ELOF1; transcription elongation factor 1"
						}
						]
					}
					]
				},
				{
					"name":"TFIIH complex",
					"children":[
					{
						"name":"100689367 Ercc3; general transcription and DNA repair factor IIH helicase subunit XPB\tK10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]"
					},
					{
						"name":"100689272 Ercc2; general transcription and DNA repair factor IIH helicase subunit XPD isoform X2\tK10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]"
					},
					{
						"name":"100751383 Gtf2h1; general transcription factor IIH subunit 1\tK03141 TFIIH1; transcription initiation factor TFIIH subunit 1"
					},
					{
						"name":"100771702 general transcription factor IIH subunit 2 isoform X1\tK03142 TFIIH2; transcription initiation factor TFIIH subunit 2"
					},
					{
						"name":"100768069 Gtf2h3; general transcription factor IIH subunit 3 isoform X1\tK03143 TFIIH3; transcription initiation factor TFIIH subunit 3"
					},
					{
						"name":"103160241 Gtf2h4; general transcription factor IIH subunit 4\tK03144 TFIIH4; transcription initiation factor TFIIH subunit 4"
					},
					{
						"name":"100772736 Gtf2h5; general transcription factor IIH subunit 5\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"113832741 general transcription factor IIH subunit 5-like\tK10845 TTDA; TFIIH basal transcription factor complex TTD-A subunit"
					},
					{
						"name":"100769780 Cdk7; cyclin-dependent kinase 7 isoform X1\tK02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
					},
					{
						"name":"100762144 Ccnh; cyclin-H\tK06634 CCNH; cyclin H"
					},
					{
						"name":"100770765 Mnat1; CDK-activating kinase assembly factor MAT1 isoform X2\tK10842 MNAT1; CDK-activating kinase assembly factor MAT1"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100772412 Rpa1; replication protein A 70 kDa DNA-binding subunit isoform X3\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100764034 Rpa2; replication protein A 32 kDa subunit isoform X2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100760299 Rpa3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"113837703 replication protein A 30 kDa subunit-like\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Other NER factors",
					"children":[
					{
						"name":"100689196 Xpa; DNA repair protein complementing XP-A cells homolog isoform X4\tK10847 XPA; DNA-repair protein complementing XP-A cells"
					},
					{
						"name":"100689377 Ercc1; DNA excision repair protein ERCC-1\tK10849 ERCC1; DNA excision repair protein ERCC-1"
					},
					{
						"name":"100689044 Ercc4; DNA repair endonuclease XPF\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
					},
					{
						"name":"100764306 Ercc5; DNA repair protein complementing XP-G cells isoform X4\tK10846 ERCC5; DNA excision repair protein ERCC-5"
					},
					{
						"name":"100767365 Lig1; DNA ligase 1 isoform X2\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"100766371 Mms19; MMS19 nucleotide excision repair protein homolog isoform X6\tK15075 MET18; DNA repair\/transcription protein MET18\/MMS19"
					},
					{
						"name":"100751075 Ccdc117; coiled-coil domain-containing protein 117 isoform X2\tK27967 CCDC117; coiled-coil domain-containing protein 117"
					},
					{
						"name":"100758531 Ciao1; probable cytosolic iron-sulfur protein assembly protein CIAO1 isoform X2\tK24730 CIAO1; cytosolic iron-sulfur protein assembly protein CIAO1"
					},
					{
						"name":"100760527 Ciao2b; cytosolic iron-sulfur assembly component 2B\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"100773305 Ciao2a; cytosolic iron-sulfur assembly component 2A\tK26403 CIAO2; cytosolic iron-sulfur assembly component 2"
					},
					{
						"name":"100760346 Cul3; cullin-3 isoform X3\tK03869 CUL3; cullin 3"
					},
					{
						"name":"100770463 Cul5; cullin-5 isoform X1\tK10612 CUL5; cullin 5"
					},
					{
						"name":"100750378 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100757582 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100757872 Eloc; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100765126 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100766274 elongin-C-like\tK03872 ELOC; elongin-C"
					},
					{
						"name":"100758808 elongin-B\tK03873 ELOB; elongin-B"
					},
					{
						"name":"100772696 Elob; elongin-B isoform X2\tK03873 ELOB; elongin-B"
					},
					{
						"name":"113833831 elongin-B-like\tK03873 ELOB; elongin-B"
					},
					{
						"name":"113833885 elongin-B-like\tK03873 ELOB; elongin-B"
					},
					{
						"name":"113834552 elongin-B-like\tK03873 ELOB; elongin-B"
					},
					{
						"name":"100754808 Eloa; elongin-A isoform X2\tK15076 ELOA; elongin-A"
					},
					{
						"name":"100761650 Ubap2l; ubiquitin-associated protein 2-like isoform X29\tK26545 UBAP2; ubiquitin-associated protein 2"
					},
					{
						"name":"100769902 Ubap2; ubiquitin-associated protein 2 isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors",
					"children":[
					{
						"name":"100768127 Msh2; DNA mismatch repair protein Msh2 isoform X2\tK08735 MSH2; DNA mismatch repair protein MSH2"
					},
					{
						"name":"100762943 Msh3; DNA mismatch repair protein Msh3 isoform X3\tK08736 MSH3; DNA mismatch repair protein MSH3"
					},
					{
						"name":"100771087 Msh6; DNA mismatch repair protein Msh6 isoform X2\tK08737 MSH6; DNA mismatch repair protein MSH6"
					}
					]
				},
				{
					"name":"MutL homologs",
					"children":[
					{
						"name":"100751321 PMS1 protein homolog 1 isoform X2\tK10864 PMS1; DNA mismatch repair protein PMS1"
					},
					{
						"name":"100769879 Mlh1; DNA mismatch repair protein Mlh1 isoform X1\tK08734 MLH1; DNA mismatch repair protein MLH1"
					},
					{
						"name":"100755917 Pms2; mismatch repair endonuclease PMS2 isoform X1\tK10858 PMS2; DNA mismatch repair protein PMS2"
					},
					{
						"name":"100755089 Mlh3; DNA mismatch repair protein Mlh3 isoform X1\tK08739 MLH3; DNA mismatch repair protein MLH3"
					}
					]
				},
				{
					"name":"DNA polymerase delta complex",
					"children":[
					{
						"name":"100773935 Pold1; DNA polymerase delta catalytic subunit isoform X2\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
					},
					{
						"name":"100762815 Pold2; DNA polymerase delta subunit 2 isoform X1\tK02328 POLD2; DNA polymerase delta subunit 2"
					},
					{
						"name":"100756090 Pold3; DNA polymerase delta subunit 3 isoform X1\tK03504 POLD3; DNA polymerase delta subunit 3"
					},
					{
						"name":"100761682 Pold4; DNA polymerase delta subunit 4 isoform X1\tK03505 POLD4; DNA polymerase delta subunit 4"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100772412 Rpa1; replication protein A 70 kDa DNA-binding subunit isoform X3\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100764034 Rpa2; replication protein A 32 kDa subunit isoform X2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100760299 Rpa3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"113837703 replication protein A 30 kDa subunit-like\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"100753096 Rfc1; replication factor C subunit 1 isoform X1\tK10754 RFC1; replication factor C subunit 1"
					},
					{
						"name":"100763988 Rfc4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"100770063 Rfc2; replication factor C subunit 2 isoform X6\tK10755 RFC2_4; replication factor C subunit 2\/4"
					},
					{
						"name":"100753174 Rfc5; replication factor C subunit 5 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
					},
					{
						"name":"100768752 Rfc3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
					}
					]
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"100689335 Pcna; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100768360 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
					},
					{
						"name":"100772338 Exo1; exonuclease 1 isoform X1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
					},
					{
						"name":"100751631 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100754755 Hmgb1; high mobility group protein B1 isoform X2\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100761755 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"113836333 high mobility group protein B1-like\tK10802 HMGB1; high mobility group protein B1"
					},
					{
						"name":"100767365 Lig1; DNA ligase 1 isoform X2\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					},
					{
						"name":"100753189 Wdr76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"MRN(MRX) complex",
					"children":[
					{
						"name":"100750877 Mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100755349 Rad50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"100750782 Nbn; nibrin isoform X2\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA1-core complex",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100750589 Bard1; BRCA1-associated RING domain protein 1 isoform X2\tK10683 BARD1; BRCA1-associated RING domain protein 1"
					}
					]
				},
				{
					"name":"BRCA1-A complex",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100766855 Abraxas1; BRCA1-A complex subunit Abraxas 1 isoform X2\tK20774 FAM175A; BRCA1-A complex subunit Abraxas"
					},
					{
						"name":"100773489 Uimc1; BRCA1-A complex subunit RAP80 isoform X1\tK20775 UIMC1; BRCA1-A complex subunit RAP80"
					},
					{
						"name":"100755943 Babam1; BRISC and BRCA1-A complex member 1 isoform X1\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
					},
					{
						"name":"100756206 Babam2; BRISC and BRCA1-A complex member 2 isoform X1\tK12173 BRE; BRCA1-A complex subunit BRE"
					},
					{
						"name":"100753541 lys-63-specific deubiquitinase BRCC36\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					},
					{
						"name":"100756268 Brcc3; lys-63-specific deubiquitinase BRCC36 isoform X2\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
					}
					]
				},
				{
					"name":"BRCA1-B complex",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100774617 Brip1; Fanconi anemia group J protein isoform X1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"100761910 Topbp1; DNA topoisomerase 2-binding protein 1 isoform X2\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
					}
					]
				},
				{
					"name":"BRCA1-C complex",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100765239 Rbbp8; DNA endonuclease RBBP8 isoform X1\tK20773 RBBP8; DNA endonuclease RBBP8 [EC:3.1.-.-]"
					},
					{
						"name":"100750877 Mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100755349 Rad50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					},
					{
						"name":"100750782 Nbn; nibrin isoform X2\tK10867 NBN; nibrin"
					}
					]
				},
				{
					"name":"BRCA complex",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100689197 Brca2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein isoform X7\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"100773675 Palb2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					},
					{
						"name":"100689324 Rad51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					}
					]
				},
				{
					"name":"RecA family proteins",
					"children":[
					{
						"name":"100689324 Rad51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"100756125 Rad51b; DNA repair protein RAD51 homolog 2 isoform X11\tK10869 RAD51L1; RAD51-like protein 1"
					},
					{
						"name":"100689078 Rad51c; DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"100766176 Rad51d; DNA repair protein RAD51 homolog 4\tK10871 RAD51L3; RAD51-like protein 3"
					},
					{
						"name":"100750706 Xrcc2; DNA repair protein XRCC2 isoform X2\tK10879 XRCC2; DNA-repair protein XRCC2"
					},
					{
						"name":"103161145 Xrcc3; DNA repair protein XRCC3 isoform X5\tK10880 XRCC3; DNA-repair protein XRCC3"
					}
					]
				},
				{
					"name":"Rad52 family proteins",
					"children":[
					{
						"name":"100689331 Rad52; DNA repair protein RAD52 homolog\tK10873 RAD52; DNA repair and recombination protein RAD52"
					}
					]
				},
				{
					"name":"Rad54 family proteins",
					"children":[
					{
						"name":"100771751 Rad54l; DNA repair and recombination protein RAD54-like\tK10875 RAD54L; DNA repair and recombination protein RAD54 and RAD54-like protein [EC:5.6.2.-]"
					},
					{
						"name":"100773503 Rad54l2; helicase ARIP4 isoform X2\tK10876 RAD54L2; RAD54-like protein 2 [EC:5.6.2.-]"
					},
					{
						"name":"100758942 Rad54b; DNA repair and recombination protein RAD54B isoform X2\tK10877 RAD54B; DNA repair and recombination protein RAD54B [EC:5.6.2.-]"
					}
					]
				},
				{
					"name":"RecQ family DNA helicases",
					"children":[
					{
						"name":"100770914 Recql; ATP-dependent DNA helicase Q1 isoform X1\tK10899 RECQL; ATP-dependent DNA helicase Q1 [EC:5.6.2.4]"
					},
					{
						"name":"100753909 Wrn; Werner syndrome ATP-dependent helicase isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
					},
					{
						"name":"100762862 Blm; Bloom syndrome protein isoform X6\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100754533 Recql4; ATP-dependent DNA helicase Q4 isoform X2\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
					},
					{
						"name":"100755041 ATP-dependent DNA helicase Q5 isoform X3\tK10902 RECQL5; ATP-dependent DNA helicase Q5 [EC:5.6.2.4]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100762862 Blm; Bloom syndrome protein isoform X6\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100758653 Top3b; DNA topoisomerase 3-beta-1 isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100772501 Top3a; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100763534 Rmi1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"100751512 Rmi2; recQ-mediated genome instability protein 2 isoform X2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"RPA (replication factor A)",
					"children":[
					{
						"name":"100772412 Rpa1; replication protein A 70 kDa DNA-binding subunit isoform X3\tK07466 RFA1; replication factor A1"
					},
					{
						"name":"100764034 Rpa2; replication protein A 32 kDa subunit isoform X2\tK10739 RFA2; replication factor A2"
					},
					{
						"name":"100760299 Rpa3; replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
					},
					{
						"name":"113837703 replication protein A 30 kDa subunit-like\tK10741 RPA4; replication factor A4"
					}
					]
				},
				{
					"name":"Protein phosphatase 4",
					"children":[
					{
						"name":"100771425 Ppp4c; serine\/threonine-protein phosphatase 4 catalytic subunit\tK15423 PPP4C; serine\/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100757531 Ppp4r1; serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X3\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"100773668 serine\/threonine-protein phosphatase 4 regulatory subunit 1 isoform X4\tK15424 PPP4R1; serine\/threonine-protein phosphatase 4 regulatory subunit 1"
					},
					{
						"name":"100758228 Ppp4r2; serine\/threonine-protein phosphatase 4 regulatory subunit 2 isoform X2\tK15425 PPP4R2; serine\/threonine-protein phosphatase 4 regulatory subunit 2"
					},
					{
						"name":"100754152 Ppp4r3a; serine\/threonine-protein phosphatase 4 regulatory subunit 3A isoform X3\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100759383 protein PPP4R3C\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100767958 Ppp4r3b; serine\/threonine-protein phosphatase 4 regulatory subunit 3B isoform X3\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100773171 protein PPP4R3C\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100773454 protein PPP4R3C\tK17491 SMEK; protein phosphatase 4 regulatory subunit 3"
					},
					{
						"name":"100764288 Ppp4r4; serine\/threonine-protein phosphatase 4 regulatory subunit 4 isoform X2\tK15426 PPP4R4; serine\/threonine-protein phosphatase 4 regulatory subunit 4"
					}
					]
				},
				{
					"name":"AP-5 complex",
					"children":[
					{
						"name":"100761023 Ap5b1; AP-5 complex subunit beta-1\tK19022 AP5B1; AP-5 complex subunit beta-1"
					},
					{
						"name":"100754336 Ap5m1; AP-5 complex subunit mu-1 isoform X3\tK19023 AP5M1; AP-5 complex subunit mu-1"
					},
					{
						"name":"100765217 Ap5s1; AP-5 complex subunit sigma-1 isoform X1\tK19024 AP5S1; AP-5 complex subunit sigma-1"
					},
					{
						"name":"100760656 Ap5z1; AP-5 complex subunit zeta-1 isoform X1\tK19025 AP5Z1; AP-5 complex subunit zeta-1"
					}
					]
				},
				{
					"name":"SMC5-SMC6 complex",
					"children":[
					{
						"name":"100758700 Smc5; structural maintenance of chromosomes protein 5 isoform X6\tK22803 SMC5; structural maintenance of chromosomes protein 5"
					},
					{
						"name":"100757987 Smc6; structural maintenance of chromosomes protein 6 isoform X5\tK22804 SMC6; structural maintenance of chromosomes protein 6"
					},
					{
						"name":"100764785 Lratd1; protein LRATD1\tK22805 FAM84A; protein FAM84A"
					},
					{
						"name":"100763072 Nsmce1; non-structural maintenance of chromosomes element 1 homolog isoform X2\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
					},
					{
						"name":"100757511 LOW QUALITY PROTEIN: E3 SUMO-protein ligase NSE2-like isoform X2\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"103159000 E3 SUMO-protein ligase NSE2 isoform X1\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
					},
					{
						"name":"100763256 non-structural maintenance of chromosomes element 3 homolog isoform X2\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"100764696 non-structural maintenance of chromosomes element 3 homolog\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"100772988 LOW QUALITY PROTEIN: non-structural maintenance of chromosomes element 3 homolog isoform X2\tK22823 NSMCE3; non-structural maintenance of chromosomes element 3"
					},
					{
						"name":"100774921 Nsmce4a; non-structural maintenance of chromosomes element 4 homolog A\tK22825 NSMCE4; non-structural maintenance of chromosomes element 4"
					},
					{
						"name":"100771887 Eid3; EP300-interacting inhibitor of differentiation 3\tK22826 EID3; EP300-interacting inhibitor of differentiation 3"
					},
					{
						"name":"100753941 Slf1; SMC5-SMC6 complex localization factor protein 1 isoform X1\tK26126 SLF1; SMC5-SMC6 complex localization factor protein 1"
					},
					{
						"name":"100756312 Slf2; SMC5-SMC6 complex localization factor protein 2 isoform X1\tK26127 SLF2; SMC5-SMC6 complex localization factor protein 2"
					},
					{
						"name":"100768496 Simc1; SUMO-interacting motif-containing protein 1 isoform X4\tK28408 SIMC1; SUMO-interacting motif-containing protein 1"
					}
					]
				},
				{
					"name":"Other HR factors",
					"children":[
					{
						"name":"100759039 Eme1; crossover junction endonuclease EME1\tK10882 EME1; crossover junction endonuclease EME1 [EC:3.1.22.-]"
					},
					{
						"name":"100765424 Eme2; probable crossover junction endonuclease EME2\tK10883 EME2; crossover junction endonuclease EME2"
					},
					{
						"name":"100765115 Exd2; exonuclease 3'-5' domain-containing protein 2 isoform X2\tK20777 EXD2; exonuclease 3'-5' domain-containing protein 2 [EC:3.1.11.1]"
					},
					{
						"name":"100770181 Mus81; crossover junction endonuclease MUS81 isoform X4\tK08991 MUS81; crossover junction endonuclease MUS81 [EC:3.1.22.-]"
					},
					{
						"name":"100753658 Sem1; LOW QUALITY PROTEIN: 26S proteasome complex subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"100754454 Swi5; DNA repair protein SWI5 homolog isoform X2\tK10991 SWI5; DNA repair protein Swi5\/Sae3"
					},
					{
						"name":"100755061 swi5-dependent recombination DNA repair protein 1 homolog isoform X2\tK10992 SFR1; Swi5-dependent recombination DNA repair protein 1"
					},
					{
						"name":"100752848 Slx1a; structure-specific endonuclease subunit SLX1 isoform X3\tK15078 SLX1; structure-specific endonuclease subunit SLX1 [EC:3.6.1.-]"
					},
					{
						"name":"100770082 Slx4; structure-specific endonuclease subunit SLX4\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"100754800 Gen1; flap endonuclease GEN homolog 1 isoform X1\tK15338 GEN1; holliday junction resolvase GEN1\/YEN1 [EC:3.1.-.-]"
					},
					{
						"name":"100765400 Spg11; spatacsin isoform X4\tK19026 SPG11; spatacsin"
					},
					{
						"name":"100759300 Zfyve26; zinc finger FYVE domain-containing protein 26 isoform X1\tK19027 ZFYVE26; zinc finger FYVE domain-containing protein 26"
					},
					{
						"name":"100772698 Rad51ap1; RAD51-associated protein 1 isoform X1\tK20778 RAD51AP1; RAD51-associated protein 1"
					},
					{
						"name":"100761063 Nucks1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X3\tK28888 NUCKS1; nuclear ubiquitous casein and cyclin-dependent kinase substrate 1"
					},
					{
						"name":"100765879 Morf4l1; mortality factor 4-like protein 1 isoform X7\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"113834833 mortality factor 4-like protein 1\tK11339 MORF4L1; mortality factor 4-like protein 1"
					},
					{
						"name":"100763736 Samhd1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1\tK22544 SAMHD1; deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [EC:3.1.5.-]"
					},
					{
						"name":"100758940 Fignl1; fidgetin-like protein 1\tK22766 FIGNL1; fidgetin-like protein 1 [EC:5.6.2.-]"
					},
					{
						"name":"100771321 Spidr; DNA repair-scaffolding protein isoform X2\tK22806 SPIDR; DNA repair-scaffolding protein"
					},
					{
						"name":"100765324 Lratd2; protein LRATD2\tK22810 FAM84B; protein FAM84B"
					},
					{
						"name":"100761522 Brat1; BRCA1-associated ATM activator 1 isoform X1\tK23112 BRAT1; BRCA1-associated ATM activator 1"
					},
					{
						"name":"100761839 Cfap410; cilia- and flagella-associated protein 410 isoform X1\tK23456 CFAP410; cilla- and flagella-associated protein"
					},
					{
						"name":"100768234 Hdgfl2; hepatoma-derived growth factor-related protein 2 isoform X5\tK25065 HDGFL2; hepatoma-derived growth factor-related protein 2"
					},
					{
						"name":"100760249 Zswim7; zinc finger SWIM domain-containing protein 7 isoform X2\tK25770 ZSWIM7; zinc finger SWIM domain-containing protein 7"
					},
					{
						"name":"100754673 Swsap1; ATPase SWSAP1\tK25771 SWSAP1; ATPase SWSAP1"
					},
					{
						"name":"100774400 Emsy; BRCA2-interacting transcriptional repressor EMSY isoform X1\tK25790 EMSY; BRCA2-interacting transcriptional repressor EMSY"
					},
					{
						"name":"100751781 Hsf2bp; heat shock factor 2-binding protein isoform X1\tK25791 HSF2BP; heat shock factor 2-binding protein"
					},
					{
						"name":"100768068 Mms22l; protein MMS22-like isoform X2\tK26125 MMS22L; protein MMS22-like"
					},
					{
						"name":"100761088 Tonsl; tonsoku-like protein isoform X1\tK09257 NFKBIL2; NF-kappa-B inhibitor-like protein 2"
					},
					{
						"name":"100769598 Bod1l1; LOW QUALITY PROTEIN: biorientation of chromosomes in cell division protein 1-like 1 isoform X5\tK27262 BOD1L1; biorientation of chromosomes in cell division protein 1-like 1"
					},
					{
						"name":"100770705 Parpbp; PCNA-interacting partner isoform X1\tK27412 PARPBP; PCNA-interacting partner"
					},
					{
						"name":"100762232 Hrob; homologous recombination OB-fold protein isoform X1\tK27803 HROB; homologous recombination OB-fold protein"
					},
					{
						"name":"100772692 Mcm8; DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
					},
					{
						"name":"100762661 Mcm9; DNA helicase MCM9 isoform X1\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
					},
					{
						"name":"100772778 Hnrnpul1; heterogeneous nuclear ribonucleoprotein U-like protein 1 isoform X2\tK15047 HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like protein 1"
					},
					{
						"name":"100756306 Hnrnpul2; heterogeneous nuclear ribonucleoprotein U-like protein 2 isoform X2\tK28611 HNRNPUL2; heterogeneous nuclear ribonucleoprotein U-like protein 2"
					},
					{
						"name":"100768063 Mrnip; MRN complex-interacting protein isoform X2\tK28623 MRNIP; MRN complex-interacting protein"
					},
					{
						"name":"100762363 Radx; RPA-related protein RADX isoform X2\tK29002 RADX; RPA-related protein RADX"
					},
					{
						"name":"100755843 Rbm6; RNA-binding protein 6 isoform X1\tK29038 RBM6; RNA-binding protein 6"
					}
					]
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"DNA-PK complex",
					"children":[
					{
						"name":"100770214 Xrcc6; X-ray repair cross-complementing protein 6\tK10884 XRCC6; ATP-dependent DNA helicase 2 subunit 1"
					},
					{
						"name":"100689306 Xrcc5; X-ray repair cross-complementing protein 5 precursor\tK10885 XRCC5; ATP-dependent DNA helicase 2 subunit 2"
					},
					{
						"name":"100770748 Prkdc; DNA-dependent protein kinase catalytic subunit isoform X1\tK06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
					}
					]
				},
				{
					"name":"MRX complex",
					"children":[
					{
						"name":"100750877 Mre11; double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
					},
					{
						"name":"100755349 Rad50; DNA repair protein RAD50 isoform X2\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
					}
					]
				},
				{
					"name":"DNA Ligase 4 complex",
					"children":[
					{
						"name":"100754640 Lig4; DNA ligase 4\tK10777 LIG4; DNA ligase 4 [EC:6.5.1.1]"
					},
					{
						"name":"100768249 DNA repair protein XRCC4 isoform X4\tK10886 XRCC4; DNA-repair protein XRCC4"
					},
					{
						"name":"100769596 Nhej1; non-homologous end-joining factor 1\tK10980 NHEJ1; non-homologous end-joining factor 1"
					}
					]
				},
				{
					"name":"X-family DNA polymerases",
					"children":[
					{
						"name":"100751096 Poll; DNA polymerase lambda isoform X1\tK03512 POLL; DNA polymerase lambda [EC:2.7.7.7 4.2.99.-]"
					},
					{
						"name":"100762233 Polm; DNA-directed DNA\/RNA polymerase mu isoform X1\tK03513 POLM; DNA polymerase mu [EC:2.7.7.7]"
					},
					{
						"name":"100755735 Dntt; DNA nucleotidylexotransferase isoform X1\tK00977 DNTT; DNA nucleotidylexotransferase [EC:2.7.7.31]"
					},
					{
						"name":"100774965 Polb; DNA polymerase beta\tK02330 POLB; DNA polymerase beta [EC:2.7.7.7 4.2.99.-]"
					}
					]
				},
				{
					"name":"Other NHEJ factors",
					"children":[
					{
						"name":"100774231 Aptx; aprataxin\tK10863 APTX; aprataxin [EC:3.6.1.70 3.6.1.71 3.6.1.72]"
					},
					{
						"name":"100765532 Aplf; aprataxin and PNK-like factor isoform X1\tK13295 APLF; aprataxin and PNK-like factor [EC:3.1.-.-]"
					},
					{
						"name":"100752196 Dclre1c; protein artemis isoform X1\tK10887 DCLRE1C; DNA cross-link repair 1C protein [EC:3.1.-.-]"
					},
					{
						"name":"100764160 Tdp2; tyrosyl-DNA phosphodiesterase 2 isoform X2\tK19619 TDP2; tyrosyl-DNA phosphodiesterase 2 [EC:3.1.4.-]"
					},
					{
						"name":"100770189 Smchd1; structural maintenance of chromosomes flexible hinge domain-containing protein 1 isoform X2\tK23113 SMCHD1; structural maintenance of chromosomes flexible hinge domain-containing protein 1"
					},
					{
						"name":"100758054 PWWP domain-containing DNA repair factor 3B\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"100766402 Pwwp3a; PWWP domain-containing DNA repair factor 3A isoform X1\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"100771029 Pwwp3b; PWWP domain-containing DNA repair factor 3B\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"113837622 PWWP domain-containing DNA repair factor 3B-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"113837734 PWWP domain-containing DNA repair factor 3B-like\tK23386 PWWP3; PWWP domain-containing DNA repair factor 3"
					},
					{
						"name":"100762994 Paxx; protein PAXX isoform X1\tK25772 PAXX; protein PAXX"
					},
					{
						"name":"100689364 Cyren; cell cycle regulator of non-homologous end joining\tK26155 CYREN; cell cycle regulator of non-homologous end joining"
					},
					{
						"name":"100771483 Jmjd8; jmjC domain-containing protein 8 isoform X1\tK25792 JMJD8; jumonji domain-containing protein 8"
					},
					{
						"name":"100773847 Shld1; shieldin complex subunit 1 isoform X1\tK26128 SHLD1; shieldin complex subunit 1"
					},
					{
						"name":"100773947 Shld2; shieldin complex subunit 2 isoform X1\tK26129 SHLD2; shieldin complex subunit 2"
					},
					{
						"name":"100766260 LOW QUALITY PROTEIN: BEN domain-containing protein 4 isoform X3\tK27845 BEND4; BEN domain-containing protein 4"
					},
					{
						"name":"100753382 Iffo1; intermediate filament family orphan 1 isoform X1\tK28738 IFFO; non-homologous end joining factor IFFO"
					},
					{
						"name":"100764698 Iffo2; intermediate filament family orphan 2 isoform X4\tK28738 IFFO; non-homologous end joining factor IFFO"
					}
					]
				}
				]
			},
			{
				"name":"FA (Fanconi anemia) pathway",
				"children":[
				{
					"name":"FA core complex",
					"children":[
					{
						"name":"100761220 Fanca; Fanconi anemia group A protein isoform X3\tK10888 FANCA; fanconi anemia group A protein"
					},
					{
						"name":"100750774 Fancb; Fanconi anemia group B protein\tK10889 FANCB; fanconi anemia group B protein"
					},
					{
						"name":"118237590 Fancc; Fanconi anemia group C protein isoform X2\tK10890 FANCC; fanconi anemia group C protein"
					},
					{
						"name":"100765848 Fance; Fanconi anemia group E protein isoform X2\tK10892 FANCE; fanconi anemia group E protein"
					},
					{
						"name":"103161842 Fancf; Fanconi anemia group F protein isoform X2\tK10893 FANCF; fanconi anemia group F protein"
					},
					{
						"name":"100689273 Fancg; Fanconi anemia group G protein\tK10894 FANCG; fanconi anemia group G protein"
					},
					{
						"name":"100759885 Fancl; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
					},
					{
						"name":"100768967 Fancm; Fanconi anemia group M protein isoform X2\tK10896 FANCM; fanconi anemia group M protein"
					},
					{
						"name":"100757600 Faap24; Fanconi anemia core complex-associated protein 24 isoform X2\tK10898 FAAP24; fanconi anemia-associated protein"
					},
					{
						"name":"100754573 Faap100; Fanconi anemia core complex-associated protein 100 isoform X4\tK10993 FAAP100; fanconi anemia core complex 100 kDa subunit"
					}
					]
				},
				{
					"name":"FA core complex binding factors",
					"children":[
					{
						"name":"100752756 Hes1; transcription factor HES-1 isoform X2\tK06054 HES1; hairy and enhancer of split 1"
					},
					{
						"name":"100765487 centromere protein S isoform X3\tK11511 APITD1; centromere protein S"
					},
					{
						"name":"100769252 Cenpx; centromere protein X isoform X1\tK15360 STRA13; centromere protein X"
					},
					{
						"name":"100754089 Ube2t; ubiquitin-conjugating enzyme E2 T isoform X1\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
					}
					]
				},
				{
					"name":"Bloom's syndrome complex (BTR)",
					"children":[
					{
						"name":"100762862 Blm; Bloom syndrome protein isoform X6\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
					},
					{
						"name":"100758653 Top3b; DNA topoisomerase 3-beta-1 isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100772501 Top3a; DNA topoisomerase 3-alpha isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
					},
					{
						"name":"100763534 Rmi1; recQ-mediated genome instability protein 1\tK10990 RMI1; RecQ-mediated genome instability protein 1"
					},
					{
						"name":"100751512 Rmi2; recQ-mediated genome instability protein 2 isoform X2\tK15365 RMI2; RecQ-mediated genome instability protein 2"
					}
					]
				},
				{
					"name":"FANCD2-I complex",
					"children":[
					{
						"name":"100757761 Fancd2; Fanconi anemia group D2 protein isoform X1\tK10891 FANCD2; fanconi anemia group D2 protein"
					},
					{
						"name":"100755795 Fanci; Fanconi anemia group I protein isoform X1\tK10895 FANCI; fanconi anemia group I protein"
					}
					]
				},
				{
					"name":"Downstream FA components",
					"children":[
					{
						"name":"100770724 Brca1; breast cancer type 1 susceptibility protein isoform X1\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
					},
					{
						"name":"100689197 Brca2; LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein isoform X7\tK08775 BRCA2; breast cancer 2 susceptibility protein"
					},
					{
						"name":"100774617 Brip1; Fanconi anemia group J protein isoform X1\tK15362 BRIP1; fanconi anemia group J protein [EC:5.6.2.3]"
					},
					{
						"name":"100773675 Palb2; partner and localizer of BRCA2 isoform X1\tK10897 PALB2; partner and localizer of BRCA2"
					}
					]
				},
				{
					"name":"Other FA pathway factors",
					"children":[
					{
						"name":"100762441 Fan1; fanconi-associated nuclease 1 isoform X1\tK15363 FAN1; fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1]"
					},
					{
						"name":"100689324 Rad51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
					},
					{
						"name":"100689078 Rad51c; DNA repair protein RAD51 homolog 3\tK10870 RAD51L2; RAD51-like protein 2"
					},
					{
						"name":"100774669 Telo2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
					},
					{
						"name":"100754655 Usp1; ubiquitin carboxyl-terminal hydrolase 1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
					},
					{
						"name":"100752446 Wdr48; WD repeat-containing protein 48 isoform X1\tK15361 WDR48; WD repeat-containing protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Other DSBR factors",
				"children":[
				{
					"name":"Protein phosphatase 6",
					"children":[
					{
						"name":"100752643 Ppp6c; serine\/threonine-protein phosphatase 6 catalytic subunit isoform X2\tK15498 PPP6C; serine\/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16]"
					},
					{
						"name":"100772081 Ppp6r1; serine\/threonine-protein phosphatase 6 regulatory subunit 1 isoform X2\tK15499 PPP6R1; serine\/threonine-protein phosphatase 6 regulatory subunit 1"
					},
					{
						"name":"100755203 Ppp6r2; serine\/threonine-protein phosphatase 6 regulatory subunit 2 isoform X12\tK15500 PPP6R2; serine\/threonine-protein phosphatase 6 regulatory subunit 2"
					},
					{
						"name":"100761104 Ppp6r3; serine\/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1\tK15501 PPP6R3; serine\/threonine-protein phosphatase 6 regulatory subunit 3"
					},
					{
						"name":"100767224 Ankrd28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X1\tK15502 ANKRD28; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A"
					},
					{
						"name":"100774011 serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X6\tK15503 ANKRD44; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B"
					},
					{
						"name":"100751169 Ankrd52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X2\tK15504 ANKRD52; serine\/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C"
					}
					]
				},
				{
					"name":"Ubiquitin ligases",
					"children":[
					{
						"name":"103162332 Rnf8; E3 ubiquitin-protein ligase RNF8 isoform X4\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
					},
					{
						"name":"100753166 Rnf168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"103159657 E3 ubiquitin-protein ligase RNF168-like\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
					},
					{
						"name":"100756964 Rnf169; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF169 isoform X4\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
					},
					{
						"name":"100758957 Herc2; E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"100757087 Wrap53; telomerase Cajal body protein 1 isoform X2\tK23314 WRAP53; telomerase Cajal body protein 1"
					},
					{
						"name":"100750447 Tprn; taperin isoform X2\tK24164 TPRN; taperin"
					},
					{
						"name":"100754258 Zcwpw1; zinc finger CW-type PWWP domain protein 1 isoform X1\tK24688 ZCWPW1; zinc finger CW-type PWWP domain protein 1"
					},
					{
						"name":"100772849 Wdr70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"100753189 Wdr76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					},
					{
						"name":"100763397 Hmces; abasic site processing protein HMCES\tK28434 HMCES; abasic site processing protein HMCES"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases",
				"children":[
				{
					"name":"100758244 Polh; DNA polymerase eta isoform X2\tK03509 POLH; DNA polymerase eta [EC:2.7.7.7]"
				},
				{
					"name":"100757066 Poli; DNA polymerase iota isoform X4\tK03510 POLI; DNA polymerase iota [EC:2.7.7.7]"
				},
				{
					"name":"100758099 Polk; DNA polymerase kappa isoform X3\tK03511 POLK; DNA polymerase kappa [EC:2.7.7.7]"
				},
				{
					"name":"100756056 Rev1; DNA repair protein REV1 isoform X1\tK03515 REV1; DNA repair protein REV1 [EC:2.7.7.-]"
				}
				]
			},
			{
				"name":"B-family DNA polymerases",
				"children":[
				{
					"name":"100774890 Rev3l; DNA polymerase zeta catalytic subunit isoform X4\tK02350 REV3L; DNA polymerase zeta [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"A-family DNA polymerase",
				"children":[
				{
					"name":"100769107 Poln; DNA polymerase nu isoform X10\tK16618 POLN; DNA polymerase nu [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"Rad6 epistasis group",
				"children":[
				{
					"name":"100768509 Ube2a; ubiquitin-conjugating enzyme E2 A isoform X2\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
				},
				{
					"name":"100750711 ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"100758252 Ube2b; ubiquitin-conjugating enzyme E2 B isoform X2\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
				},
				{
					"name":"100758311 Rad18; E3 ubiquitin-protein ligase RAD18 isoform X1\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"100759084 E3 ubiquitin-protein ligase RAD18\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"100751958 Hltf; helicase-like transcription factor\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"100757965 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100759587 ubiquitin-conjugating enzyme E2 variant 1-like isoform X2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100764742 Ube2v2; ubiquitin-conjugating enzyme E2 variant 2 isoform X4\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100769951 ubiquitin-conjugating enzyme E2 variant 1-like isoform X2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"103159460 Ube2v1; ubiquitin-conjugating enzyme E2 variant 1 isoform X2\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"113838824 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"118237734 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"118239776 ubiquitin-conjugating enzyme E2 variant 1-like\tK10704 UBE2V; ubiquitin-conjugating enzyme E2 variant"
				},
				{
					"name":"100752830 Ube2n; ubiquitin-conjugating enzyme E2 N isoform X2\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
				}
				]
			},
			{
				"name":"Other TLS factors",
				"children":[
				{
					"name":"100689335 Pcna; proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"100768360 proliferating cell nuclear antigen-like\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"100755621 Pclaf; PCNA-associated factor\tK28763 PCLAF; PCNA-associated factor"
				},
				{
					"name":"100770705 Parpbp; PCNA-interacting partner isoform X1\tK27412 PARPBP; PCNA-interacting partner"
				},
				{
					"name":"100764217 Sprtn; sprT-like domain-containing protein Spartan isoform X1\tK24051 SPRTN; SprT-like domain-contaning protein Spartan"
				},
				{
					"name":"100755380 Dppa5; developmental pluripotency-associated 5 protein\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				},
				{
					"name":"100770850 developmental pluripotency-associated protein 5A\tK28975 DPPA5; developmental pluripotency-associated protein 5"
				}
				]
			}
			]
		},
		{
			"name":"Check point factors",
			"children":[
			{
				"name":"Rad9-Hus1-Rad1 complex",
				"children":[
				{
					"name":"100761098 Rad9a; cell cycle checkpoint control protein RAD9A isoform X1\tK10994 RAD9A; cell cycle checkpoint control protein RAD9A [EC:3.1.11.2]"
				},
				{
					"name":"100764146 Rad9b; cell cycle checkpoint control protein RAD9B\tK10995 RAD9B; cell cycle checkpoint control protein RAD9B"
				},
				{
					"name":"100754140 Hus1; checkpoint protein HUS1 isoform X1\tK10903 HUS1; HUS1 checkpoint protein"
				},
				{
					"name":"100756111 Hus1b; checkpoint protein HUS1B isoform X2\tK10996 HUS1B; checkpoint protein HUS1B"
				},
				{
					"name":"100756835 Rad1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"HRAD17(Rad24)-RFC complex",
				"children":[
				{
					"name":"100773436 Rad17; cell cycle checkpoint protein RAD17\tK06662 HRAD17; cell cycle checkpoint protein"
				},
				{
					"name":"100763988 Rfc4; replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"100770063 Rfc2; replication factor C subunit 2 isoform X6\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"100753174 Rfc5; replication factor C subunit 5 isoform X1\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"100768752 Rfc3; replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"Rad17-Mec3-Ddc1 complex",
				"children":[
				{
					"name":"100756835 Rad1; cell cycle checkpoint protein RAD1\tK02830 HRAD1; cell cycle checkpoint protein [EC:3.1.11.2]"
				}
				]
			},
			{
				"name":"FPC (fork protection complex)",
				"children":[
				{
					"name":"100764475 Timeless; protein timeless homolog isoform X2\tK10997 TIMELESS; replication fork protection complex subunit TIMELESS\/Tof1\/Swi1"
				},
				{
					"name":"100768167 Tipin; TIMELESS-interacting protein isoform X2\tK10998 TIPIN; replication fork protection complex subunit TIPIN\/Csm3\/Swi3"
				},
				{
					"name":"100768047 Clspn; claspin isoform X1\tK25773 CLSPN; claspin"
				}
				]
			},
			{
				"name":"Triple T complex",
				"children":[
				{
					"name":"100774669 Telo2; telomere length regulation protein TEL2 homolog isoform X1\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"100758713 Tti1; TELO2-interacting protein 1 homolog\tK20403 TTI1; TELO2-interacting protein 1"
				},
				{
					"name":"100760553 Tti2; TELO2-interacting protein 2 isoform X1\tK23115 TTI2; TELO2-interacting protein 2"
				}
				]
			},
			{
				"name":"BAG6-UBL4A-GET4 complex",
				"children":[
				{
					"name":"100763893 Bag6; large proline-rich protein BAG6 isoform X1\tK23390 BAG6; large proline-rich protein BAG6"
				},
				{
					"name":"100761792 Ubl4a; ubiquitin-like protein 4A isoform X2\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"100769727 Ubl4b; ubiquitin-like protein 4B\tK23388 UBL4; ubiquitin-like protein 4"
				},
				{
					"name":"100769304 Get4; Golgi to ER traffic protein 4 homolog isoform X3\tK23387 GET4; golgi to ER traffic protein 4"
				}
				]
			},
			{
				"name":"SOSS complex",
				"children":[
				{
					"name":"100768339 Ints3; integrator complex subunit 3 isoform X1\tK13140 INTS3; integrator complex subunit 3 (SOSS complex subunit A)"
				},
				{
					"name":"100751749 Nabp2; SOSS complex subunit B1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"100753014 SOSS complex subunit B2-like\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"100755797 Nabp1; SOSS complex subunit B2 isoform X1\tK28889 NABP; SOSS complex subunit B"
				},
				{
					"name":"100770269 Inip; SOSS complex subunit C isoform X1\tK28890 INIP; SOSS complex subunit C"
				}
				]
			},
			{
				"name":"Other check point factors",
				"children":[
				{
					"name":"100766256 Atr; serine\/threonine-protein kinase ATR\tK06640 ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
				},
				{
					"name":"100762140 Atrip; ATR-interacting protein isoform X1\tK10905 ATRIP; ATR interacting protein"
				},
				{
					"name":"100750682 Etaa1; ewing's tumor-associated antigen 1 isoform X2\tK28856 ETAA1; Ewing's tumor-associated antigen 1"
				},
				{
					"name":"100754226 serine-protein kinase ATM isoform X6\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"100682525 Tp53; cellular tumor antigen p53\tK04451 TP53; tumor protein p53"
				},
				{
					"name":"100751099 Chek1; serine\/threonine-protein kinase Chk1 isoform X1\tK02216 CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
				},
				{
					"name":"100769280 Chek2; serine\/threonine-protein kinase Chk2 isoform X1\tK06641 CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
				},
				{
					"name":"100767961 Cdc25a; M-phase inducer phosphatase 1\tK06645 CDC25A; M-phase inducer phosphatase 1 [EC:3.1.3.48]"
				},
				{
					"name":"100765509 Cdc25b; M-phase inducer phosphatase 2\tK05866 CDC25B; M-phase inducer phosphatase 2 [EC:3.1.3.48]"
				},
				{
					"name":"100773417 Cdc25c; M-phase inducer phosphatase 3 isoform X4\tK05867 CDC25C; M-phase inducer phosphatase 3 [EC:3.1.3.48]"
				},
				{
					"name":"100751694 Ywhaq; 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100757122 Ywhab; 14-3-3 protein beta\/alpha\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100758637 14-3-3 protein theta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100766119 Ywhaz; 14-3-3 protein zeta\/delta\tK16197 YWHAB_Q_Z; 14-3-3 protein beta\/theta\/zeta"
				},
				{
					"name":"100770325 14-3-3 protein gamma isoform X2\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"100771398 Ywhah; 14-3-3 protein eta isoform X2\tK16198 YWHAG_H; 14-3-3 protein gamma\/eta"
				},
				{
					"name":"100753603 14-3-3 protein epsilon isoform X2\tK06630 YWHAE; 14-3-3 protein epsilon"
				},
				{
					"name":"100760394 Nav2; neuron navigator 2 isoform X1\tK19483 NAV2; neuron navigator 2 [EC:5.6.2.4]"
				},
				{
					"name":"100750772 Wee2; wee1-like protein kinase 2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"100753258 Wee1; wee1-like protein kinase isoform X2\tK06632 WEE1; wee1-like protein kinase [EC:2.7.11.1]"
				},
				{
					"name":"100753886 Per1; period circadian protein homolog 1 isoform X1\tK21944 PER1; period circadian protein 1"
				},
				{
					"name":"100772001 Per2; period circadian protein homolog 2 isoform X1\tK02633 PER2; period circadian protein 2"
				},
				{
					"name":"100762774 period circadian protein homolog 3 isoform X11\tK21945 PER3; period circadian protein 3"
				},
				{
					"name":"100756160 Mdc1; mediator of DNA damage checkpoint protein 1\tK20780 MDC1; mediator of DNA damage checkpoint protein 1"
				},
				{
					"name":"100689375 Pls3; plastin-3\tK17336 PLS3; plastin-3"
				},
				{
					"name":"100765585 Aen; apoptosis-enhancing nuclease\tK18340 AEN; apoptosis-enhancing nuclease [EC:3.1.-.-]"
				},
				{
					"name":"100762491 Plk3; serine\/threonine-protein kinase PLK3 isoform X2\tK08862 PLK3; polo-like kinase 3 [EC:2.7.11.21]"
				},
				{
					"name":"100757116 Plk5; inactive serine\/threonine-protein kinase PLK5 isoform X2\tK19596 PLK5; inactive serine\/threonine-protein kinase PLK5"
				},
				{
					"name":"100752822 Nek5; serine\/threonine-protein kinase Nek5 isoform X2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"100759305 Nek1; serine\/threonine-protein kinase Nek1\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"100761888 Nek4; serine\/threonine-protein kinase Nek4 isoform X2\tK08857 NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
				},
				{
					"name":"100770613 Nek10; serine\/threonine-protein kinase Nek10\tK20879 NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
				},
				{
					"name":"100764820 Nek11; LOW QUALITY PROTEIN: serine\/threonine-protein kinase Nek11\tK20880 NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
				},
				{
					"name":"100769724 Donson; protein downstream neighbor of Son isoform X2\tK22422 DONSON; protein downstream neighbor of Son"
				},
				{
					"name":"100755240 Kank4; KN motif and ankyrin repeat domain-containing protein 4 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100756045 Kank2; KN motif and ankyrin repeat domain-containing protein 2\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"100759671 Kank1; KN motif and ankyrin repeat domain-containing protein 1 isoform X1\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103160001 Kank3; KN motif and ankyrin repeat domain-containing protein 3 isoform X3\tK22808 KANK; KN motif and ankyrin repeat domain-containing protein"
				},
				{
					"name":"103162910 Klln; LOW QUALITY PROTEIN: killin isoform X2\tK23389 KLLN; killin"
				},
				{
					"name":"100759934 Chmp4c; charged multivesicular body protein 4c\tK24782 CHMP4C; charged multivesicular body protein 4C"
				},
				{
					"name":"100752222 Vps4b; vacuolar protein sorting-associated protein 4B isoform X2\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"100763128 Vps4a; vacuolar protein sorting-associated protein 4A\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				},
				{
					"name":"100751587 Zfyve19; abscission\/NoCut checkpoint regulator isoform X1\tK24778 ZFYVE19; abscission\/NoCut checkpoint regulator"
				},
				{
					"name":"100752836 Sde2; replication stress response regulator SDE2 isoform X2\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"100769396 Krcc1; lysine-rich coiled-coil protein 1\tK29003 KRCC1; lysine-rich coiled-coil protein 1"
				},
				{
					"name":"100757663 Blcap; bladder cancer-associated protein\tK29062 BLCAP; apoptosis inducing factor BLCAP"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerases",
				"children":[
				{
					"name":"100764158 Polq; DNA polymerase theta isoform X1\tK02349 POLQ; DNA polymerase theta [EC:2.7.7.7]"
				},
				{
					"name":"100758378 Mybbp1a; myb-binding protein 1A isoform X3\tK02331 POL5; DNA polymerase phi [EC:2.7.7.7]"
				},
				{
					"name":"100753873 Primpol; DNA-directed primase\/polymerase protein isoform X1\tK22761 PRIMPOL; DNA-directed primase\/polymerase protein [EC:2.7.7.102 2.7.7.7]"
				}
				]
			},
			{
				"name":"Nucleases",
				"children":[
				{
					"name":"100761854 Trex1; three-prime repair exonuclease 1 isoform X1\tK10790 TREX1; three prime repair exonuclease 1 [EC:3.1.11.2]"
				},
				{
					"name":"100771308 Trex2; three prime repair exonuclease 2\tK10791 TREX2; three prime repair exonuclease 2 [EC:3.1.11.2]"
				},
				{
					"name":"100750521 Dclre1a; DNA cross-link repair 1A protein isoform X1\tK15340 DCLRE1A; DNA cross-link repair 1A protein"
				},
				{
					"name":"100759525 Dclre1b; 5' exonuclease Apollo isoform X1\tK15341 DCLRE1B; DNA cross-link repair 1B protein [EC:3.1.-.-]"
				},
				{
					"name":"100753327 Exo5; exonuclease V\tK17815 EXO5; exonuclease V [EC:3.1.-.-]"
				},
				{
					"name":"100760952 Endov; endonuclease V isoform X1\tK21813 ENDOV; endonuclease V [EC:3.1.26.-]"
				},
				{
					"name":"100771558 Zranb3; DNA annealing helicase and endonuclease ZRANB3 isoform X2\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"100753605 Ankle1; ankyrin repeat and LEM domain-containing protein 1 isoform X6\tK21411 ANKLE1; ankyrin repeat and LEM domain-containing protein 1"
				}
				]
			},
			{
				"name":"Helicases",
				"children":[
				{
					"name":"100767150 Helq; helicase POLQ-like isoform X4\tK19178 HELQ; POLQ-like helicase [EC:5.6.2.4]"
				},
				{
					"name":"100751043 Ercc6l2; DNA excision repair protein ERCC-6-like 2 isoform X3\tK20098 ERCC6L2; DNA excision repair protein ERCC-6-like 2 [EC:5.6.2.-]"
				}
				]
			},
			{
				"name":"PSO4 complex",
				"children":[
				{
					"name":"100751402 Prpf19; pre-mRNA-processing factor 19 isoform X2\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
				},
				{
					"name":"100756825 Cdc5l; cell division cycle 5-like protein isoform X2\tK12860 CDC5L; pre-mRNA-splicing factor CDC5\/CEF1"
				},
				{
					"name":"100758667 Bcas2; pre-mRNA-splicing factor SPF27\tK12861 BCAS2; pre-mRNA-splicing factor SPF27"
				},
				{
					"name":"100773980 Plrg1; pleiotropic regulator 1\tK12862 PLRG1; pleiotropic regulator 1"
				}
				]
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100761298 Nudt15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"100770207 Nudt1; 7,8-dihydro-8-oxoguanine triphosphatase isoform X3\tK17816 NUDT1; 8-oxo-dGTP diphosphatase \/ 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56]"
				},
				{
					"name":"100765600 Nudt18; 8-oxo-dGDP phosphatase NUDT18\tK17817 NUDT18; 8-oxo-dGDP phosphatase [EC:3.6.1.58]"
				},
				{
					"name":"100761578 Dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"107978202 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"100761591 Rrm1; ribonucleoside-diphosphate reductase large subunit\tK10807 RRM1; ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1]"
				},
				{
					"name":"100752542 Rrm2; ribonucleoside-diphosphate reductase subunit M2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				},
				{
					"name":"100768429 Rrm2b; ribonucleoside-diphosphate reductase subunit M2 B isoform X2\tK10808 RRM2; ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"SSBR (single strand breaks repair)",
			"children":[
			{
				"name":"Direct repair",
				"children":[
				{
					"name":"100767894 Mgmt; methylated-DNA--protein-cysteine methyltransferase isoform X2\tK00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]"
				}
				]
			},
			{
				"name":"BER (base exicision repair)",
				"children":[
				{
					"name":"DNA glycosylases",
					"children":[
					{
						"name":"100753421 Ung; uracil-DNA glycosylase isoform X2\tK03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]"
					},
					{
						"name":"100770488 Smug1; single-strand selective monofunctional uracil DNA glycosylase isoform X1\tK10800 SMUG1; single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-]"
					},
					{
						"name":"100758892 Mpg; DNA-3-methyladenine glycosylase\tK03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]"
					},
					{
						"name":"100752384 Mutyh; adenine DNA glycosylase isoform X1\tK03575 mutY; A\/G-specific adenine glycosylase [EC:3.2.2.31]"
					},
					{
						"name":"100755553 Nthl1; endonuclease III-like protein 1 isoform X1\tK10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]"
					}
					]
				},
				{
					"name":"AP endonucleases"
				},
				{
					"name":"RecJ"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"DNA polymerase I"
				}
				]
			},
			{
				"name":"NER (nucleotide excision repair)",
				"children":[
				{
					"name":"GGR (global genome repair) factors"
				},
				{
					"name":"TCR (transcription coupled repair) factors",
					"children":[
					{
						"name":"DNA-directed RNA polymerase complex (RNAP)"
					},
					{
						"name":"TRCF (transcription-repair coupling factor)"
					}
					]
				}
				]
			},
			{
				"name":"MMR (mismatch excision repair)",
				"children":[
				{
					"name":"Mismatch and loop recognition factors"
				},
				{
					"name":"Molecular matchmaker"
				},
				{
					"name":"Strand discrimination factor"
				},
				{
					"name":"DNA exonucleases"
				},
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"DNA ligase"
				},
				{
					"name":"Other MMR factors",
					"children":[
					{
						"name":"100772064 Ssbp1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DSBR (double strand breaks repair)",
			"children":[
			{
				"name":"HR (homologous recombination)",
				"children":[
				{
					"name":"RecBC pathway proteins"
				},
				{
					"name":"RecFOR pathway proteins"
				},
				{
					"name":"AddAB pathway proteins"
				},
				{
					"name":"Other HR factor"
				},
				{
					"name":"Archaeal homologous recombinant proteins"
				}
				]
			},
			{
				"name":"NHEJ (non-homologous end-joining)",
				"children":[
				{
					"name":"Two-component NHEJ DNA repair complex"
				},
				{
					"name":"SHIIR (short-homology-independent illegitimate recombination)",
					"children":[
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				},
				{
					"name":"SHDIR (short-homology-dependent illegitimate recombination)",
					"children":[
					{
						"name":"RecET pathway"
					},
					{
						"name":"Facilitator"
					},
					{
						"name":"Supressor"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"TLS (translesion DNA synthesis) factors",
			"children":[
			{
				"name":"Y-family DNA polymerases"
			},
			{
				"name":"Other SOS response factors",
				"children":[
				{
					"name":"100772064 Ssbp1; single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"Other factors with a suspected DNA repair function",
			"children":[
			{
				"name":"DNA polymerase"
			},
			{
				"name":"DNA helicases"
			},
			{
				"name":"Modulation of nucleotide pools",
				"children":[
				{
					"name":"100761298 Nudt15; nucleotide triphosphate diphosphatase NUDT15\tK03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]"
				},
				{
					"name":"100761578 Dut; deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial isoform X1\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				},
				{
					"name":"107978202 deoxyuridine 5'-triphosphate nucleotidohydrolase-like\tK01520 dut; dUTP diphosphatase [EC:3.6.1.23]"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		}
		]
	}
	]
}