{
	"name":"ecb04121",
	"children":[
	{
		"name":"Ubiquitins and ubiquitin-like proteins",
		"children":[
		{
			"name":"Ubiquitins",
			"children":[
			{
				"name":"100033924 UBC; ubiquitin C\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"100059289 UBC; polyubiquitin-C\tK08770 UBB_C; ubiquitin B\/C"
			},
			{
				"name":"100071005 UBA52; ubiquitin-60S ribosomal protein L40\tK02927 RP-L40e; ubiquitin-large subunit ribosomal protein L40e"
			},
			{
				"name":"100052644 RPS27A; ubiquitin-40S ribosomal protein S27a\tK02977 RP-S27Ae; ubiquitin-small subunit ribosomal protein S27Ae"
			}
			]
		},
		{
			"name":"Ubiquitin-like proteins (UBLs)",
			"children":[
			{
				"name":"102149821 UBD; ubiquitin D\tK12157 UBD; ubiquitin D"
			},
			{
				"name":"100051307 NEDD8; NEDD8\tK12158 NEDD8; ubiquitin-like protein Nedd8"
			},
			{
				"name":"100033998 FAU; ubiquitin-like protein fubi and ribosomal protein S30\tK02983 RP-S30e; small subunit ribosomal protein S30e"
			},
			{
				"name":"100066364 ISG15; ubiquitin-like protein ISG15\tK12159 ISG15; ubiquitin cross-reactive protein"
			},
			{
				"name":"100049890 small ubiquitin-related modifier 2\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100067107 SUMO1; small ubiquitin-related modifier 1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100630015 SUMO3; small ubiquitin-related modifier 3 isoform X1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100630536 SUMO2; small ubiquitin-related modifier 2 isoform X1\tK12160 SUMO; small ubiquitin-related modifier"
			},
			{
				"name":"100053911 GABARAPL1; gamma-aminobutyric acid receptor-associated protein-like 1 isoform X2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"100055295 GABARAPL2; gamma-aminobutyric acid receptor-associated protein-like 2\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"111775730 GABARAP; gamma-aminobutyric acid receptor-associated protein\tK08341 GABARAP; GABA(A) receptor-associated protein"
			},
			{
				"name":"100073160 ATG12; ubiquitin-like protein ATG12 isoform X1\tK08336 ATG12; ubiquitin-like protein ATG12"
			},
			{
				"name":"100066985 URM1; ubiquitin-related modifier 1\tK12161 URM1; ubiquitin related modifier 1"
			},
			{
				"name":"100066289 UFM1; ubiquitin-fold modifier 1\tK12162 UFM1; ubiquitin-fold modifier 1"
			},
			{
				"name":"100629621 UBL3; ubiquitin-like protein 3\tK28515 UBL3; membrane-anchored ubiquitin-fold protein"
			},
			{
				"name":"100051390 ZFAND4; AN1-type zinc finger protein 4 isoform X1\tK12163 ZFAND4; AN1-type zinc finger protein 4"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-activating enzymes (E1)",
		"children":[
		{
			"name":"Ubiquitin activating enzyme",
			"children":[
			{
				"name":"100060792 UBA1; ubiquitin-like modifier-activating enzyme 1\tK03178 UBE1; ubiquitin-activating enzyme E1 [EC:6.2.1.45]"
			}
			]
		},
		{
			"name":"UBL-activating enzymes",
			"children":[
			{
				"name":"100071215 SAE1; SUMO-activating enzyme subunit 1 isoform X1\tK10684 UBLE1A; ubiquitin-like 1-activating enzyme E1 A [EC:6.2.1.45]"
			},
			{
				"name":"100057234 UBA2; SUMO-activating enzyme subunit 2 isoform X1\tK10685 UBLE1B; ubiquitin-like 1-activating enzyme E1 B [EC:6.2.1.45]"
			},
			{
				"name":"100053395 UBA3; NEDD8-activating enzyme E1 catalytic subunit isoform X1\tK10686 UBA3; NEDD8-activating enzyme E1 [EC:6.2.1.64]"
			},
			{
				"name":"100065540 NAE1; NEDD8-activating enzyme E1 regulatory subunit isoform X2\tK04532 NAE1; NEDD8-activating enzyme E1 regulatory subunit"
			},
			{
				"name":"102147399 MOCS3; adenylyltransferase and sulfurtransferase MOCS3\tK11996 MOCS3; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
			},
			{
				"name":"100052911 UBA5; ubiquitin-like modifier-activating enzyme 5 isoform X1\tK12164 UBA5; ubiquitin-like modifier-activating enzyme 5"
			},
			{
				"name":"100052809 UBA7; ubiquitin-like modifier-activating enzyme 7 isoform X1\tK10698 UBE1L; ubiquitin-activating enzyme E1-like [EC:6.2.1.45]"
			},
			{
				"name":"100067272 UBA6; ubiquitin-like modifier-activating enzyme 6\tK10699 UBE1L2; ubiquitin-activating enzyme E1-like protein 2 [EC:6.2.1.45]"
			},
			{
				"name":"100051544 ATG7; ubiquitin-like modifier-activating enzyme ATG7 isoform X3\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin-conjugating enzymes (E2)",
		"children":[
		{
			"name":"Ubiquitin-conjugating enzymes",
			"children":[
			{
				"name":"100058679 UBE2A; ubiquitin-conjugating enzyme E2 A\tK10573 UBE2A; ubiquitin-conjugating enzyme E2 A [EC:2.3.2.23]"
			},
			{
				"name":"100062920 UBE2B; ubiquitin-conjugating enzyme E2 B\tK10574 UBE2B; ubiquitin-conjugating enzyme E2 B [EC:2.3.2.23]"
			},
			{
				"name":"100056334 UBE2C; ubiquitin-conjugating enzyme E2 C\tK06688 UBE2C; ubiquitin-conjugating enzyme E2 C [EC:2.3.2.23]"
			},
			{
				"name":"100062598 UBE2D1; ubiquitin-conjugating enzyme E2 D1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100064918 UBE2D4; ubiquitin-conjugating enzyme E2 D4 isoform X1\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100630045 UBE2D2; ubiquitin-conjugating enzyme E2 D2 isoform X2\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100630481 UBE2D3; ubiquitin-conjugating enzyme E2 D3 isoform X3\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"111771588 ubiquitin-conjugating enzyme E2 D2-like\tK06689 UBE2D; ubiquitin-conjugating enzyme E2 D [EC:2.3.2.23]"
			},
			{
				"name":"100060214 UBE2E1; ubiquitin-conjugating enzyme E2 E1 isoform X1\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100061057 ubiquitin-conjugating enzyme E2 E2 isoform X2\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100067766 UBE2E3; ubiquitin-conjugating enzyme E2 E3\tK20217 UBE2E; ubiquitin-conjugating enzyme E2 E [EC:2.3.2.23]"
			},
			{
				"name":"100072717 UBE2G1; ubiquitin-conjugating enzyme E2 G1\tK10575 UBE2G1; ubiquitin-conjugating enzyme E2 G1 [EC:2.3.2.23]"
			},
			{
				"name":"100056215 UBE2G2; ubiquitin-conjugating enzyme E2 G2 isoform X1\tK04555 UBE2G2; ubiquitin-conjugating enzyme E2 G2 [EC:2.3.2.23]"
			},
			{
				"name":"100071949 UBE2H; ubiquitin-conjugating enzyme E2 H isoform X2\tK10576 UBE2H; ubiquitin-conjugating enzyme E2 H [EC:2.3.2.23]"
			},
			{
				"name":"100071009 UBE2J1; ubiquitin-conjugating enzyme E2 J1\tK10578 UBE2J1; ubiquitin-conjugating enzyme E2 J1 [EC:2.3.2.23]"
			},
			{
				"name":"100061534 UBE2J2; ubiquitin-conjugating enzyme E2 J2\tK04554 UBE2J2; ubiquitin-conjugating enzyme E2 J2 [EC:2.3.2.23]"
			},
			{
				"name":"100055027 UBE2K; ubiquitin-conjugating enzyme E2 K isoform X1\tK04649 UBE2K; ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:2.3.2.23]"
			},
			{
				"name":"100058286 LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 L3\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"100630004 UBE2L3; ubiquitin-conjugating enzyme E2 L3 isoform X1\tK04552 UBE2L3; ubiquitin-conjugating enzyme E2 L3 [EC:2.3.2.23]"
			},
			{
				"name":"100066866 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 isoform X4\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"100051493 UBE2N; ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"102150222 ubiquitin-conjugating enzyme E2 N\tK10580 UBE2N; ubiquitin-conjugating enzyme E2 N [EC:2.3.2.23]"
			},
			{
				"name":"100058843 UBE2O; (E3-independent) E2 ubiquitin-conjugating enzyme isoform X1\tK10581 UBE2O; ubiquitin-conjugating enzyme E2 O [EC:2.3.2.24]"
			},
			{
				"name":"100050645 UBE2Q2; ubiquitin-conjugating enzyme E2 Q2 isoform X1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"100062653 UBE2Q1; ubiquitin-conjugating enzyme E2 Q1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"106782352 UBE2QL1; ubiquitin-conjugating enzyme E2Q-like protein 1\tK10582 UBE2Q; ubiquitin-conjugating enzyme E2 Q [EC:2.3.2.23]"
			},
			{
				"name":"100051527 CDC34; ubiquitin-conjugating enzyme E2 R1 isoform X1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"100068420 UBE2R2; ubiquitin-conjugating enzyme E2 R2 isoform X1\tK02207 UBE2R; ubiquitin-conjugating enzyme E2 R [EC:2.3.2.23]"
			},
			{
				"name":"100055998 UBE2S; ubiquitin-conjugating enzyme E2 S\tK10583 UBE2S; ubiquitin-conjugating enzyme E2 S [EC:2.3.2.23]"
			},
			{
				"name":"100063899 UBE2T; ubiquitin-conjugating enzyme E2 T\tK13960 UBE2T; ubiquitin-conjugating enzyme E2 T [EC:2.3.2.23]"
			},
			{
				"name":"100069934 UBE2U; ubiquitin-conjugating enzyme E2 U isoform X2\tK10584 UBE2U; ubiquitin-conjugating enzyme E2 U [EC:2.3.2.23]"
			},
			{
				"name":"100051082 UBE2W; ubiquitin-conjugating enzyme E2 W\tK10688 UBE2W; ubiquitin-conjugating enzyme E2 W [EC:2.3.2.23 2.3.2.25]"
			},
			{
				"name":"100069535 UBE2Z; ubiquitin-conjugating enzyme E2 Z\tK10585 UBE2Z; ubiquitin-conjugating enzyme E2 Z [EC:2.3.2.23]"
			},
			{
				"name":"100070568 BIRC6; baculoviral IAP repeat-containing protein 6 isoform X1\tK10586 BIRC6; baculoviral IAP repeat-containing protein 6 (apollon) [EC:2.3.2.23]"
			}
			]
		},
		{
			"name":"UBL-conjugating enzymes",
			"children":[
			{
				"name":"100065385 UBE2I; SUMO-conjugating enzyme UBC9\tK10577 UBE2I; ubiquitin-conjugating enzyme E2 I"
			},
			{
				"name":"100057575 UBE2F; NEDD8-conjugating enzyme UBE2F isoform X1\tK10687 UBE2F; ubiquitin-conjugating enzyme E2 F [EC:2.3.2.34]"
			},
			{
				"name":"100064883 UBE2M; NEDD8-conjugating enzyme Ubc12\tK10579 UBE2M; ubiquitin-conjugating enzyme E2 M [EC:2.3.2.34]"
			},
			{
				"name":"100066866 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 isoform X4\tK04553 UBE2L6; ubiquitin\/ISG15-conjugating enzyme E2 L6 [EC:2.3.2.23]"
			},
			{
				"name":"100061410 ATG3; ubiquitin-like-conjugating enzyme ATG3 isoform X2\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
			},
			{
				"name":"100073249 ATG10; ubiquitin-like-conjugating enzyme ATG10 isoform X5\tK17888 ATG10L; ubiquitin-like-conjugating enzyme ATG10"
			},
			{
				"name":"100066229 UFC1; ubiquitin-fold modifier-conjugating enzyme 1\tK12165 UFC1; ufm1-conjugating enzyme 1"
			}
			]
		}
		]
	},
	{
		"name":"Ubiquitin ligases (E3)",
		"children":[
		{
			"name":"HECT type E3",
			"children":[
			{
				"name":"100050725 UBE3A; ubiquitin-protein ligase E3A isoform X1\tK10587 UBE3A; ubiquitin-protein ligase E3 A [EC:2.3.2.26]"
			},
			{
				"name":"100059725 UBE3B; ubiquitin-protein ligase E3B isoform X1\tK10588 UBE3B; ubiquitin-protein ligase E3 B [EC:2.3.2.26]"
			},
			{
				"name":"100067217 UBE3C; ubiquitin-protein ligase E3C isoform X1\tK10589 UBE3C; ubiquitin-protein ligase E3 C [EC:2.3.2.26]"
			},
			{
				"name":"100070024 UBE3D; E3 ubiquitin-protein ligase E3D isoform X1\tK20803 UBE3D; ubiquitin-protein ligase E3 D [EC:2.3.2.26]"
			},
			{
				"name":"100063241 SMURF1; E3 ubiquitin-protein ligase SMURF1 isoform X1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"100064082 SMURF2; E3 ubiquitin-protein ligase SMURF2 isoform X1\tK04678 SMURF; E3 ubiquitin ligase SMURF1\/2 [EC:2.3.2.26]"
			},
			{
				"name":"100069340 ITCH; E3 ubiquitin-protein ligase Itchy homolog\tK05632 ITCH; E3 ubiquitin-protein ligase Itchy [EC:2.3.2.26]"
			},
			{
				"name":"100055725 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1\tK05633 WWP1; NEDD4-like E3 ubiquitin-protein ligase WWP1 [EC:2.3.2.26]"
			},
			{
				"name":"100067291 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2\tK05630 WWP2; NEDD4-like E3 ubiquitin-protein ligase WWP2 [EC:2.3.2.26]"
			},
			{
				"name":"100056934 TRIP12; E3 ubiquitin-protein ligase TRIP12 isoform X1\tK10590 TRIP12; E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]"
			},
			{
				"name":"100054735 NEDD4; E3 ubiquitin-protein ligase NEDD4 isoform X2\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
			},
			{
				"name":"100054395 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like isoform X7\tK13305 NEDD4L; E3 ubiquitin-protein ligase NEDD4-like [EC:2.3.2.26]"
			},
			{
				"name":"100060375 HUWE1; E3 ubiquitin-protein ligase HUWE1 isoform X3\tK10592 HUWE1; E3 ubiquitin-protein ligase HUWE1 [EC:2.3.2.26]"
			},
			{
				"name":"100051130 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 isoform X1\tK22370 AREL1; apoptosis-resistant E3 ubiquitin protein ligase 1 [EC:2.3.2.26]"
			},
			{
				"name":"100062126 UBR5; E3 ubiquitin-protein ligase UBR5 isoform X1\tK10593 EDD1; E3 ubiquitin-protein ligase EDD1 [EC:2.3.2.26]"
			},
			{
				"name":"100049939 G2E3; G2\/M phase-specific E3 ubiquitin-protein ligase\tK22371 G2H3; G2\/M phase-specific E3 ubiquitin-protein ligase [EC:2.3.2.26]"
			},
			{
				"name":"100067089 HERC1; probable E3 ubiquitin-protein ligase HERC1 isoform X1\tK10594 HERC1; E3 ubiquitin-protein ligase HERC1 [EC:2.3.2.26]"
			},
			{
				"name":"100050955 HERC2; E3 ubiquitin-protein ligase HERC2 isoform X1\tK10595 HERC2; E3 ubiquitin-protein ligase HERC2 [EC:2.3.2.26]"
			},
			{
				"name":"100053167 HERC3; probable E3 ubiquitin-protein ligase HERC3 isoform X1\tK10614 HERC3; E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]"
			},
			{
				"name":"100062999 HERC4; probable E3 ubiquitin-protein ligase HERC4 isoform X5\tK10615 HERC4; E3 ubiquitin-protein ligase HERC4 [EC:2.3.2.26]"
			},
			{
				"name":"100071887 HACE1; E3 ubiquitin-protein ligase HACE1 isoform X1\tK12166 HACE1; E3 ubiquitin-protein ligase HACE1 [EC:2.3.2.26]"
			},
			{
				"name":"100064499 HECW1; E3 ubiquitin-protein ligase HECW1 isoform X1\tK12167 HECW1; E3 ubiquitin-protein ligase HECW1 [EC:2.3.2.26]"
			},
			{
				"name":"100055015 HECW2; E3 ubiquitin-protein ligase HECW2 isoform X1\tK12168 HECW2; E3 ubiquitin-protein ligase HECW2 [EC:2.3.2.26]"
			},
			{
				"name":"100050203 HECTD1; E3 ubiquitin-protein ligase HECTD1 isoform X1\tK12231 HECTD1; E3 ubiquitin-protein ligase HECTD1 [EC:2.3.2.26]"
			},
			{
				"name":"100071434 HECTD2; probable E3 ubiquitin-protein ligase HECTD2 isoform X1\tK12232 HECTD2; E3 ubiquitin-protein ligase HECTD2 [EC:2.3.2.26]"
			},
			{
				"name":"100065625 HECTD3; E3 ubiquitin-protein ligase HECTD3\tK12233 HECTD3; E3 ubiquitin-protein ligase HECTD3 [EC:2.3.2.26]"
			},
			{
				"name":"100056981 HECTD4; probable E3 ubiquitin-protein ligase HECTD4 isoform X1\tK17849 HECTD4; E3 ubiquitin-protein ligase HECTD4 [EC:2.3.2.26]"
			},
			{
				"name":"HECT type E3 associated proteins",
				"children":[
				{
					"name":"100054516 NDFIP2; NEDD4 family-interacting protein 2\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"100072138 NDFIP1; NEDD4 family-interacting protein 1\tK25839 NDFIP; NEDD4 family-interacting protein"
				},
				{
					"name":"100058182 N4BP3; NEDD4-binding protein 3\tK26473 N4BP3; NEDD4-binding protein 3"
				},
				{
					"name":"100057445 C13H16orf72; UPF0472 protein C16orf72 homolog isoform X1\tK27699 HAPSTR1; HUWE1-associated protein modifying stress responses 1"
				},
				{
					"name":"100055351 UPF0472 protein C16orf72\tK27700 HAPSTR2; HUWE1-associated protein modifying stress responses 2"
				}
				]
			}
			]
		},
		{
			"name":"U-box type E3",
			"children":[
			{
				"name":"100062986 UBE4A; ubiquitin conjugation factor E4 A\tK10596 UBE4A; ubiquitin conjugation factor E4 A [EC:2.3.2.27]"
			},
			{
				"name":"100057243 UBE4B; ubiquitin conjugation factor E4 B isoform X3\tK10597 UBE4B; ubiquitin conjugation factor E4 B [EC:2.3.2.27]"
			},
			{
				"name":"100066999 STUB1; E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
			},
			{
				"name":"100057423 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 isoform X1\tK10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]"
			},
			{
				"name":"100059076 PRPF19; pre-mRNA-processing factor 19\tK10599 PRPF19; pre-mRNA-processing factor 19 [EC:2.3.2.27]"
			},
			{
				"name":"100033991 RBBP6; E3 ubiquitin-protein ligase RBBP6 isoform X1\tK10624 RBBP6; E3 ubiquitin-protein ligase RBBP6 [EC:2.3.2.27]"
			},
			{
				"name":"100052706 UBOX5; RING finger protein 37 isoform X1\tK10600 UBOX5; U-box domain-containing protein 5 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Single Ring-finger type E3",
			"children":[
			{
				"name":"BRE1 proteins",
				"children":[
				{
					"name":"100054384 RNF20; E3 ubiquitin-protein ligase BRE1A isoform X1\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				},
				{
					"name":"100065215 RNF40; E3 ubiquitin-protein ligase BRE1B\tK10696 BRE1; E3 ubiquitin-protein ligase BRE1 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"CBL proteins",
				"children":[
				{
					"name":"100071403 CBL; E3 ubiquitin-protein ligase CBL isoform X1\tK04707 CBL; E3 ubiquitin-protein ligase CBL [EC:2.3.2.27]"
				},
				{
					"name":"100061819 CBLB; E3 ubiquitin-protein ligase CBL-B isoform X1\tK22517 CBLB; E3 ubiquitin-protein ligase CBL-B [EC:2.3.2.27]"
				},
				{
					"name":"100147299 CBLC; E3 ubiquitin-protein ligase CBL-C isoform X1\tK22518 CBLC; E3 ubiquitin-protein ligase CBL-C [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"SINA (Seven in absentia) proteins",
				"children":[
				{
					"name":"100057532 SIAH1; E3 ubiquitin-protein ligase SIAH1 isoform X2\tK04506 SIAH1; E3 ubiquitin-protein ligase SIAH1 [EC:2.3.2.27]"
				},
				{
					"name":"100034000 SIAH2; E3 ubiquitin-protein ligase SIAH2\tK08742 SIAH2; E3 ubiquitin-protein ligase SIAH2 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Ligand of Numb proteins",
				"children":[
				{
					"name":"100054101 LNX1; E3 ubiquitin-protein ligase LNX isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100061190 LNX2; ligand of Numb protein X 2 isoform X1\tK10692 LNX1_2; ligand of Numb protein X 1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100053517 PDZRN4; PDZ domain-containing RING finger protein 4 isoform X3\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				},
				{
					"name":"100061813 PDZRN3; E3 ubiquitin-protein ligase PDZRN3 isoform X2\tK15682 PDZRN3_4; ligand of Numb protein X 3\/4 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"March proteins",
				"children":[
				{
					"name":"100061618 MARCH1; E3 ubiquitin-protein ligase MARCH1 isoform X2\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"100062110 MARCH8; E3 ubiquitin-protein ligase MARCH8 isoform X1\tK10656 MARCH1_8; E3 ubiquitin-protein ligase MARCH1\/8 [EC:2.3.2.27]"
				},
				{
					"name":"100049857 MARCH2; E3 ubiquitin-protein ligase MARCH2\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"111767820 MARCH3; E3 ubiquitin-protein ligase MARCH3\tK10657 MARCH2_3; E3 ubiquitin-protein ligase MARCH2\/3 [EC:2.3.2.27]"
				},
				{
					"name":"100050538 MARCH4; E3 ubiquitin-protein ligase MARCH4\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"100053712 MARCH9; E3 ubiquitin-protein ligase MARCH9\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"100070090 MARCH11; E3 ubiquitin-protein ligase MARCH11\tK10659 MARCH4_9_11; E3 ubiquitin-protein ligase MARCH4\/9\/11 [EC:2.3.2.27]"
				},
				{
					"name":"100061898 MARCH5; E3 ubiquitin-protein ligase MARCH5 isoform X2\tK10660 MARCH5; E3 ubiquitin-protein ligase MARCH5 [EC:2.3.2.27]"
				},
				{
					"name":"100070883 MARCH6; E3 ubiquitin-protein ligase MARCH6 isoform X1\tK10661 MARCH6; E3 ubiquitin-protein ligase MARCH6 [EC:2.3.2.27]"
				},
				{
					"name":"100051194 MARCH7; E3 ubiquitin-protein ligase MARCH7 isoform X1\tK10662 MARCH7; E3 ubiquitin-protein ligase MARCH7 [EC:2.3.2.27]"
				},
				{
					"name":"100064936 MARCH10; probable E3 ubiquitin-protein ligase MARCH10 isoform X4\tK10665 MARCH10; E3 ubiquitin-protein ligase MARCH10 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"MDM2\/MDM4 proteins",
				"children":[
				{
					"name":"100052084 MDM2; E3 ubiquitin-protein ligase Mdm2 isoform X1\tK06643 MDM2; E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27]"
				},
				{
					"name":"100050113 MDM4; protein Mdm4 isoform X2\tK10127 MDM4; protein Mdm4"
				}
				]
			},
			{
				"name":"NFX1 proteins",
				"children":[
				{
					"name":"100053795 NFX1; transcriptional repressor NF-X1 isoform X1\tK12236 NFX1; transcriptional repressor NF-X1"
				},
				{
					"name":"100054437 NFXL1; NF-X1-type zinc finger protein NFXL1 isoform X1\tK15683 NFXL1; NF-X1-type zinc finger protein NFXL1"
				}
				]
			},
			{
				"name":"Pellino proteins",
				"children":[
				{
					"name":"100051401 PELI1; E3 ubiquitin-protein ligase pellino homolog 1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"100052587 PELI3; E3 ubiquitin-protein ligase pellino homolog 3 isoform X1\tK11964 PELI; pellino [EC:2.3.2.27]"
				},
				{
					"name":"100057689 PELI2; E3 ubiquitin-protein ligase pellino homolog 2 isoform X1\tK11964 PELI; pellino [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"Peripheral membrane proteins",
				"children":[
				{
					"name":"100064074 PEX10; peroxisome biogenesis factor 10\tK13346 PEX10; peroxin-10 [EC:2.3.2.27]"
				},
				{
					"name":"100058090 PEX12; peroxisome assembly protein 12\tK13345 PEX12; peroxin-12"
				},
				{
					"name":"100059654 PEX2; peroxisome biogenesis factor 2\tK06664 PEX2; peroxin-2 [EC:2.3.2.27 2.3.2.36]"
				}
				]
			},
			{
				"name":"RBR proteins",
				"children":[
				{
					"name":"100057832 PRKN; E3 ubiquitin-protein ligase parkin isoform X1\tK04556 PARK2; parkin [EC:2.3.2.31]"
				},
				{
					"name":"100061269 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 isoform X1\tK11967 ANKIB1; ankyrin repeat and IBR domain-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"100063423 ARIH1; E3 ubiquitin-protein ligase ARIH1 isoform X1\tK11968 ARIH1; ariadne-1 [EC:2.3.2.31]"
				},
				{
					"name":"100053691 ARIH2; E3 ubiquitin-protein ligase ARIH2 isoform X3\tK11969 ARIH2; ariadne-2 [EC:2.3.2.31]"
				},
				{
					"name":"100067987 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				},
				{
					"name":"100061332 RNF14; E3 ubiquitin-protein ligase RNF14 isoform X1\tK11971 RNF14; E3 ubiquitin-protein ligase RNF14 [EC:2.3.2.31]"
				},
				{
					"name":"100055939 RNF19A; E3 ubiquitin-protein ligase RNF19A\tK11972 RNF19A; E3 ubiquitin-protein ligase RNF19A [EC:2.3.2.31]"
				},
				{
					"name":"100070073 RNF19B; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF19B\tK11973 RNF19B; E3 ubiquitin-protein ligase RNF19B [EC:2.3.2.31]"
				},
				{
					"name":"100058179 RFFL; E3 ubiquitin-protein ligase rififylin isoform X1\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"100059653 RNF34; E3 ubiquitin-protein ligase RNF34 isoform X1\tK20804 RNF34; E3 ubiquitin-protein ligase RNF34 [EC:2.3.2.31]"
				},
				{
					"name":"100052124 RNF144B; E3 ubiquitin-protein ligase RNF144B\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"100057284 RNF144A; E3 ubiquitin-protein ligase RNF144A isoform X1\tK11975 RNF144; E3 ubiquitin-protein ligase RNF144 [EC:2.3.2.31]"
				},
				{
					"name":"100069836 RNF168; E3 ubiquitin-protein ligase RNF168\tK20779 RNF168; E3 ubiquitin-protein ligase RNF168 [EC:2.3.2.31]"
				},
				{
					"name":"100064984 RNF169; E3 ubiquitin-protein ligase RNF169\tK20805 RNF169; E3 ubiquitin-protein ligase RNF169 [EC:2.3.2.31]"
				},
				{
					"name":"100050237 RNF183; probable E3 ubiquitin-protein ligase RNF183\tK22157 RNF183; E3 ubiquitin-protein ligase RNF183 [EC:2.3.2.31]"
				},
				{
					"name":"100059097 RNF216; E3 ubiquitin-protein ligase RNF216 isoform X1\tK11976 RNF216; E3 ubiquitin-protein ligase RNF216 [EC:2.3.2.31]"
				},
				{
					"name":"100073006 RNF217; probable E3 ubiquitin-protein ligase RNF217\tK11977 RNF217; E3 ubiquitin-protein ligase RNF217 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"TRAF proteins",
				"children":[
				{
					"name":"100068006 TRAF2; TNF receptor-associated factor 2 isoform X1\tK03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]"
				},
				{
					"name":"100055119 TRAF5; TNF receptor-associated factor 5\tK09849 TRAF5; TNF receptor-associated factor 5"
				},
				{
					"name":"100052296 TRAF6; TNF receptor-associated factor 6\tK03175 TRAF6; TNF receptor-associated factor 6 [EC:2.3.2.27]"
				},
				{
					"name":"100065698 TRAF7; E3 ubiquitin-protein ligase TRAF7 isoform X1\tK10646 TRAF7; E3 ubiquitin-protein ligase TRAF7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"TRIM\/RBCC proteins",
				"children":[
				{
					"name":"100054631 MID2; probable E3 ubiquitin-protein ligase MID2 isoform X2\tK10647 TRIM1; midline 2 [EC:2.3.2.27]"
				},
				{
					"name":"100055164 TRIM3; tripartite motif-containing protein 3\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"100062188 TRIM2; tripartite motif-containing protein 2 isoform X1\tK11997 TRIM2_3; tripartite motif-containing protein 2\/3"
				},
				{
					"name":"102147803 TRIM4; E3 ubiquitin-protein ligase TRIM4 isoform X1\tK11998 TRIM4; tripartite motif-containing protein 4 [EC:2.3.2.27]"
				},
				{
					"name":"100054534 E3 ubiquitin-protein ligase TRIM22 isoform X1\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"100069440 LOW QUALITY PROTEIN: tripartite motif-containing protein 5-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"102149883 tripartite motif-containing protein 5\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"106780875 LOW QUALITY PROTEIN: tripartite motif-containing protein 34-like\tK10648 TRIM5; tripartite motif-containing protein 5 [EC:2.3.2.27]"
				},
				{
					"name":"100054490 E3 ubiquitin-protein ligase TRIM22 isoform X1\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100069506 TRIM22; E3 ubiquitin-protein ligase TRIM22\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100568303 TRIM6; tripartite motif-containing protein 6\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100568304 TRIM34; tripartite motif-containing protein 34\tK11999 TRIM6_22_34; tripartite motif-containing protein 6\/22\/34"
				},
				{
					"name":"100066054 TRIM7; E3 ubiquitin-protein ligase TRIM7 isoform X3\tK12000 TRIM7; tripartite motif-containing protein 7"
				},
				{
					"name":"100147211 TRIM8; probable E3 ubiquitin-protein ligase TRIM8\tK12001 TRIM8; tripartite motif-containing protein 8 [EC:2.3.2.27]"
				},
				{
					"name":"100051245 TRIM67; tripartite motif-containing protein 67 isoform X1\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"100066749 TRIM9; E3 ubiquitin-protein ligase TRIM9 isoform X1\tK10649 TRIM9_67; tripartite motif-containing protein 9\/67"
				},
				{
					"name":"100051786 TRIM10; tripartite motif-containing protein 10\tK12002 TRIM10; tripartite motif-containing protein 10"
				},
				{
					"name":"100061497 TRIM11; E3 ubiquitin-protein ligase TRIM11\tK10650 TRIM11; tripartite motif-containing protein 11 [EC:2.3.2.27]"
				},
				{
					"name":"100055194 TRIM13; E3 ubiquitin-protein ligase TRIM13 isoform X2\tK12003 TRIM13; tripartite motif-containing protein 13 [EC:2.3.2.27]"
				},
				{
					"name":"100064095 TRIM14; tripartite motif-containing protein 14 isoform X2\tK12004 TRIM14; tripartite motif-containing protein 14"
				},
				{
					"name":"100056525 TRIM15; tripartite motif-containing protein 15\tK12005 TRIM15; tripartite motif-containing protein 15"
				},
				{
					"name":"100146229 TRIM16; tripartite motif-containing protein 16\tK12006 TRIM16; tripartite motif-containing protein 16 [EC:2.3.2.27]"
				},
				{
					"name":"100060943 TRIM17; E3 ubiquitin-protein ligase TRIM17\tK12007 TRIM17; tripartite motif-containing protein 17 [EC:2.3.2.27]"
				},
				{
					"name":"100049999 MID1; E3 ubiquitin-protein ligase Midline-1\tK08285 TRIM18; midline 1 [EC:2.3.2.27]"
				},
				{
					"name":"100066782 TRIM21; E3 ubiquitin-protein ligase TRIM21 isoform X1\tK10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]"
				},
				{
					"name":"100050517 TRIM23; E3 ubiquitin-protein ligase TRIM23\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"111769716 E3 ubiquitin-protein ligase TRIM23 isoform X1\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"111772291 E3 ubiquitin-protein ligase TRIM23\tK07963 TRIM23; tripartite motif-containing protein 23 [EC:2.3.2.27]"
				},
				{
					"name":"100066810 TRIM24; transcription intermediary factor 1-alpha isoform X1\tK08881 TRIM24; tripartite motif-containing protein 24 [EC:2.3.2.27]"
				},
				{
					"name":"100060051 E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"100146440 E3 ubiquitin\/ISG15 ligase TRIM25 isoform X2\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"100147035 TRIM25; E3 ubiquitin\/ISG15 ligase TRIM25\tK10652 TRIM25; tripartite motif-containing protein 25 [EC:2.3.2.27]"
				},
				{
					"name":"100051726 TRIM26; tripartite motif-containing protein 26\tK12008 TRIM26; tripartite motif-containing protein 26"
				},
				{
					"name":"100060192 TRIM27; zinc finger protein RFP isoform X1\tK12009 TRIM27; tripartite motif-containing protein 27 [EC:2.3.2.27]"
				},
				{
					"name":"100064831 TRIM28; transcription intermediary factor 1-beta isoform X1\tK08882 TRIM28; tripartite motif-containing protein 28 [EC:2.3.2.27]"
				},
				{
					"name":"100071461 TRIM29; tripartite motif-containing protein 29 isoform X3\tK12010 TRIM29; tripartite motif-containing protein 29"
				},
				{
					"name":"102150785 TRIM31; E3 ubiquitin-protein ligase TRIM31\tK12011 TRIM31; tripartite motif-containing protein 31 [EC:2.3.2.27]"
				},
				{
					"name":"100066864 TRIM32; E3 ubiquitin-protein ligase TRIM32\tK10607 TRIM32; tripartite motif-containing protein 32 [EC:2.3.2.27]"
				},
				{
					"name":"100065226 TRIM33; E3 ubiquitin-protein ligase TRIM33 isoform X1\tK08883 TRIM33; tripartite motif-containing protein 33 [EC:2.3.2.27]"
				},
				{
					"name":"100060341 TRIM35; tripartite motif-containing protein 35\tK12012 TRIM35; tripartite motif-containing protein 35"
				},
				{
					"name":"100064283 TRIM36; E3 ubiquitin-protein ligase TRIM36\tK12013 TRIM36; tripartite motif-containing protein 36 [EC:2.3.2.27]"
				},
				{
					"name":"100057121 TRIM37; E3 ubiquitin-protein ligase TRIM37 isoform X11\tK10608 TRIM37; tripartite motif-containing protein 37 [EC:2.3.2.27]"
				},
				{
					"name":"100052917 TRIM38; E3 ubiquitin-protein ligase TRIM38\tK12014 TRIM38; tripartite motif-containing protein 38 [EC:2.3.2.27]"
				},
				{
					"name":"102151116 E3 ubiquitin-protein ligase TRIM39\tK12015 TRIM39; tripartite motif-containing protein 39 \/ bloodthirsty-related gene family protein [EC:2.3.2.27]"
				},
				{
					"name":"100056572 TRIM40; tripartite motif-containing protein 40 isoform X2\tK12016 TRIM40; tripartite motif-containing protein 40"
				},
				{
					"name":"100057719 TRIM41; E3 ubiquitin-protein ligase TRIM41 isoform X2\tK12017 TRIM41; tripartite motif-containing protein 41 [EC:2.3.2.27]"
				},
				{
					"name":"100051616 TRIM42; tripartite motif-containing protein 42\tK12018 TRIM42; tripartite motif-containing protein 42"
				},
				{
					"name":"100059942 tripartite motif-containing protein 43-like\tK12019 TRIM43S; tripartite motif-containing protein 43\/48\/49\/64\/77"
				},
				{
					"name":"100059975 tripartite motif-containing protein 43\tK12019 TRIM43S; tripartite motif-containing protein 43\/48\/49\/64\/77"
				},
				{
					"name":"100060102 tripartite motif-containing protein 64\tK12019 TRIM43S; tripartite motif-containing protein 43\/48\/49\/64\/77"
				},
				{
					"name":"100067248 TRIM44; tripartite motif-containing protein 44 isoform X1\tK12020 TRIM44; tripartite motif-containing protein 44"
				},
				{
					"name":"100066246 TRIM45; tripartite motif-containing protein 45 isoform X2\tK12021 TRIM45; tripartite motif-containing protein 45"
				},
				{
					"name":"100057262 TRIM46; tripartite motif-containing protein 46 isoform X2\tK12022 TRIM46; tripartite motif-containing protein 46"
				},
				{
					"name":"100059340 TRIM47; tripartite motif-containing protein 47\tK12023 TRIM47; tripartite motif-containing protein 47"
				},
				{
					"name":"100059823 TRIM50; E3 ubiquitin-protein ligase TRIM50 isoform X1\tK12024 TRIM50_73_74; tripartite motif-containing protein 50\/73\/74"
				},
				{
					"name":"100630126 TRIM52; LOW QUALITY PROTEIN: tripartite motif-containing protein 52\tK12025 TRIM52; tripartite motif-containing protein 52"
				},
				{
					"name":"100071225 TRIM54; tripartite motif-containing protein 54\tK10653 TRIM54; tripartite motif-containing protein 54"
				},
				{
					"name":"100052338 TRIM55; tripartite motif-containing protein 55 isoform X1\tK10654 TRIM55; tripartite motif-containing protein 55"
				},
				{
					"name":"100060136 TRIM56; E3 ubiquitin-protein ligase TRIM56\tK12026 TRIM56; tripartite motif-containing protein 56 [EC:2.3.2.27]"
				},
				{
					"name":"100055620 TRIM58; E3 ubiquitin-protein ligase TRIM58\tK12027 TRIM58; tripartite motif-containing protein 58 [EC:2.3.2.27]"
				},
				{
					"name":"100049895 TRIM59; tripartite motif-containing protein 59\tK12028 TRIM59; tripartite motif-containing protein 59"
				},
				{
					"name":"100061588 tripartite motif-containing protein 60-like\tK12029 TRIM60_61; tripartite motif-containing protein 60\/61"
				},
				{
					"name":"100055660 TRIM62; E3 ubiquitin-protein ligase TRIM62 isoform X1\tK12030 TRIM62; tripartite motif-containing protein 62 [EC:2.3.2.27]"
				},
				{
					"name":"100071234 TRIM63; E3 ubiquitin-protein ligase TRIM63\tK10655 TRIM63; tripartite motif-containing protein 63 [EC:2.3.2.27]"
				},
				{
					"name":"100059306 TRIM65; tripartite motif-containing protein 65 isoform X1\tK12031 TRIM65; tripartite motif-containing protein 65"
				},
				{
					"name":"100070991 TRIM66; tripartite motif-containing protein 66 isoform X5\tK12032 TRIM66; tripartite motif-containing protein 66"
				},
				{
					"name":"100053519 E3 ubiquitin-protein ligase TRIM68 isoform X1\tK12033 TRIM68; tripartite motif-containing protein 68 [EC:2.3.2.27]"
				},
				{
					"name":"100056035 TRIM69; E3 ubiquitin-protein ligase TRIM69 isoform X1\tK12034 TRIM69; tripartite motif-containing protein 69 [EC:2.3.2.27]"
				},
				{
					"name":"100056593 TRIM71; E3 ubiquitin-protein ligase TRIM71\tK12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]"
				},
				{
					"name":"100063230 TRIM72; tripartite motif-containing protein 72\tK12036 TRIM72; tripartite motif-containing protein 72"
				},
				{
					"name":"100068191 LOW QUALITY PROTEIN: putative tripartite motif-containing protein 75\tK12037 TRIM75; tripartite motif-containing protein 75"
				},
				{
					"name":"100068208 putative tripartite motif-containing protein 75\tK12037 TRIM75; tripartite motif-containing protein 75"
				},
				{
					"name":"100068320 putative tripartite motif-containing protein 75\tK12037 TRIM75; tripartite motif-containing protein 75"
				}
				]
			},
			{
				"name":"UBR box proteins",
				"children":[
				{
					"name":"100056497 UBR1; E3 ubiquitin-protein ligase UBR1 isoform X2\tK10625 UBR1; E3 ubiquitin-protein ligase UBR1 [EC:2.3.2.27]"
				},
				{
					"name":"100054695 UBR2; E3 ubiquitin-protein ligase UBR2 isoform X5\tK10626 UBR2; E3 ubiquitin-protein ligase UBR2 [EC:2.3.2.27]"
				},
				{
					"name":"100063165 UBR3; E3 ubiquitin-protein ligase UBR3 isoform X1\tK11978 UBR3; E3 ubiquitin-protein ligase UBR3 [EC:2.3.2.27]"
				},
				{
					"name":"100071944 UBR4; E3 ubiquitin-protein ligase UBR4 isoform X9\tK10691 UBR4; E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27]"
				},
				{
					"name":"100064025 UBR7; putative E3 ubiquitin-protein ligase UBR7\tK11979 UBR7; E3 ubiquitin-protein ligase UBR7 [EC:2.3.2.27]"
				}
				]
			},
			{
				"name":"ATL proteins"
			},
			{
				"name":"Other single Ring-finger type E3",
				"children":[
				{
					"name":"100061759 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100056971 AIRE; autoimmune regulator\tK10603 AIRE; autoimmune regulator"
				},
				{
					"name":"100050577 BFAR; bifunctional apoptosis regulator isoform X1\tK15684 BFAR; bifunctional apoptosis regulator"
				},
				{
					"name":"100061273 BIRC2; baculoviral IAP repeat-containing protein 2\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"100068894 BIRC3; baculoviral IAP repeat-containing protein 3\tK16060 BIRC2_3; baculoviral IAP repeat-containing protein 2\/3"
				},
				{
					"name":"100060870 XIAP; E3 ubiquitin-protein ligase XIAP isoform X1\tK04725 XIAP; E3 ubiquitin-protein ligase XIAP [EC:2.3.2.27]"
				},
				{
					"name":"100147373 BIRC7; baculoviral IAP repeat-containing protein 7\tK16061 BIRC7_8; baculoviral IAP repeat-containing protein 7\/8"
				},
				{
					"name":"100057742 BRAP; BRCA1-associated protein isoform X1\tK10632 BRAP; BRCA1-associated protein [EC:2.3.2.27]"
				},
				{
					"name":"100051990 BRCA1; breast cancer type 1 susceptibility protein isoform X4\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"100050845 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X4\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"100059563 ZNF645; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNF645\tK15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]"
				},
				{
					"name":"100072568 CCNB1IP1; E3 ubiquitin-protein ligase CCNB1IP1\tK10639 CCNB1IP1; E3 ubiquitin-protein ligase CCNP1IP1 [EC:2.3.2.27]"
				},
				{
					"name":"100061394 CHFR; E3 ubiquitin-protein ligase CHFR isoform X1\tK10644 CHFR; E3 ubiquitin-protein ligase CHFR [EC:2.3.2.27]"
				},
				{
					"name":"100065026 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X1\tK10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]"
				},
				{
					"name":"100063149 DCST1; E3 ubiquitin-protein ligase DCST1 isoform X1\tK22375 DCST1; E3 ubiquitin-protein ligase DCST1 [EC:2.3.2.27]"
				},
				{
					"name":"100050618 DTX3; probable E3 ubiquitin-protein ligase DTX3 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100051299 DTX1; E3 ubiquitin-protein ligase DTX1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100060632 DTX3L; E3 ubiquitin-protein ligase DTX3L\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100060906 DTX2; probable E3 ubiquitin-protein ligase DTX2 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100066645 DTX4; E3 ubiquitin-protein ligase DTX4 isoform X1\tK06058 DTX; deltex [EC:2.3.2.27]"
				},
				{
					"name":"100061685 DZIP3; E3 ubiquitin-protein ligase DZIP3\tK10642 DZIP3; E3 ubiquitin-protein ligase DZIP3 [EC:2.3.2.27]"
				},
				{
					"name":"100065770 FANCL; E3 ubiquitin-protein ligase FANCL isoform X1\tK10606 FANCL; E3 ubiquitin-protein ligase FANCL [EC:2.3.2.27]"
				},
				{
					"name":"100067474 KCMF1; E3 ubiquitin-protein ligase KCMF1 isoform X1\tK22376 KCMF1; E3 ubiquitin-protein ligase KCMF1 [EC:2.3.2.27]"
				},
				{
					"name":"100070527 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 isoform X1\tK10641 LRSAM1; E3 ubiquitin-protein ligase LRSAM1 [EC:2.3.2.27]"
				},
				{
					"name":"100065649 LTN1; E3 ubiquitin-protein ligase listerin\tK22377 LTN1; E3 ubiquitin-protein ligase listerin [EC:2.3.2.27]"
				},
				{
					"name":"100061688 MAP3K1; mitogen-activated protein kinase kinase kinase 1\tK04416 MAP3K1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
				},
				{
					"name":"100052950 MEX3B; RNA-binding protein MEX3B\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100063974 MEX3A; RNA-binding protein MEX3A\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100069803 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100629298 MEX3D; LOW QUALITY PROTEIN: RNA-binding protein MEX3D\tK15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]"
				},
				{
					"name":"100069818 MGRN1; E3 ubiquitin-protein ligase MGRN1 isoform X1\tK10604 MGRN1; E3 ubiquitin-protein ligase MGRN1 [EC:2.3.2.27]"
				},
				{
					"name":"100060229 MIB1; E3 ubiquitin-protein ligase MIB1 isoform X2\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"100065291 MIB2; E3 ubiquitin-protein ligase MIB2 isoform X1\tK10645 MIB; E3 ubiquitin-protein ligase mind-bomb [EC:2.3.2.27]"
				},
				{
					"name":"100057038 MKRN2; probable E3 ubiquitin-protein ligase makorin-2 isoform X1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100060875 MKRN3; probable E3 ubiquitin-protein ligase makorin-3\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100065893 MKRN1; E3 ubiquitin-protein ligase makorin-1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"102150369 E3 ubiquitin-protein ligase makorin-1\tK15687 MKRN; E3 ubiquitin-protein ligase makorin [EC:2.3.2.27]"
				},
				{
					"name":"100058446 MUL1; mitochondrial ubiquitin ligase activator of NFKB 1 isoform X1\tK15688 MUL1; E3 ubiquitin-protein ligase MUL1 [EC:2.3.2.27]"
				},
				{
					"name":"100053014 MYCBP2; E3 ubiquitin-protein ligase MYCBP2\tK10693 MYCBP2; RCR-type E3 ubiquitin transferase [EC:2.3.2.33]"
				},
				{
					"name":"100065647 MYLIP; E3 ubiquitin-protein ligase MYLIP\tK10637 MYLIP; E3 ubiquitin-protein ligase MYLIP [EC:2.3.2.27]"
				},
				{
					"name":"100059635 NEURL1; E3 ubiquitin-protein ligase NEURL1 isoform X1\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"100069885 NEURL1B; E3 ubiquitin-protein ligase NEURL1B\tK01931 NEUR; protein neuralized [EC:2.3.2.27]"
				},
				{
					"name":"100062289 NEURL3; E3 ubiquitin-protein ligase NEURL3\tK15689 NEURL3; E3 ubiquitin-protein ligase NEURL3 [EC:2.3.2.27]"
				},
				{
					"name":"100066209 NHLRC1; E3 ubiquitin-protein ligase NHLRC1\tK10602 NHLRC1; E3 ubiquitin-protein ligase NHLRC1 [EC:2.3.2.27]"
				},
				{
					"name":"100049956 RNF219; RING finger protein 219\tK24091 OBI1; ORC ubiquitin ligase 1 [EC:2.3.2.27]"
				},
				{
					"name":"100065473 PJA1; E3 ubiquitin-protein ligase Praja-1 isoform X3\tK10633 PJA1; E3 ubiquitin-protein ligase Praja1 [EC:2.3.2.27]"
				},
				{
					"name":"100064609 PJA2; E3 ubiquitin-protein ligase Praja-2\tK10634 PJA2; E3 ubiquitin-protein ligase Praja2 [EC:2.3.2.27]"
				},
				{
					"name":"100052645 RAD18; E3 ubiquitin-protein ligase RAD18 isoform X2\tK10627 RAD18; E3 ubiquitin-protein ligase RAD18 [EC:2.3.2.27]"
				},
				{
					"name":"100049810 RAG1; V(D)J recombination-activating protein 1\tK10628 RAG1; V(D)J recombination-activating protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100057332 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 isoform X1\tK10144 RCHY1; RING finger and CHY zinc finger domain-containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100052499 RC3H1; roquin-1 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"100067476 RC3H2; roquin-2 isoform X1\tK15690 RC3H; RING finger and CCCH-type zinc finger domain-containing protein"
				},
				{
					"name":"100061855 COP1; E3 ubiquitin-protein ligase RFWD2 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
				},
				{
					"name":"100055114 RFWD3; E3 ubiquitin-protein ligase RFWD3 isoform X1\tK15691 RFWD3; E3 ubiquitin-protein ligase RFWD3 [EC:2.3.2.27]"
				},
				{
					"name":"100056141 RNF2; E3 ubiquitin-protein ligase RING2\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100061452 RING1; E3 ubiquitin-protein ligase RING1\tK10695 RNF1_2; E3 ubiquitin-protein ligase RNF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100051309 RNF4; E3 ubiquitin-protein ligase RNF4 isoform X1\tK22651 RNF4; E3 ubiquitin-protein ligase RNF4 [EC:2.3.2.27]"
				},
				{
					"name":"100051626 RNF5; E3 ubiquitin-protein ligase RNF5\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"100058463 RNF185; E3 ubiquitin-protein ligase RNF185\tK10666 RNF5_185; E3 ubiquitin-protein ligase RNF5\/185 [EC:2.3.2.27]"
				},
				{
					"name":"100050743 RNF6; E3 ubiquitin-protein ligase RNF6 isoform X1\tK22753 RNF6; E3 ubiquitin-protein ligase RNF6 [EC:2.3.2.27]"
				},
				{
					"name":"100053995 RNF8; E3 ubiquitin-protein ligase RNF8 isoform X1\tK10667 RNF8; E3 ubiquitin-protein ligase RNF8 [EC:2.3.2.27]"
				},
				{
					"name":"100050260 RNF10; RING finger protein 10\tK26979 RNF10; E3 ubiquitin-protein ligase RNF10 [EC:2.3.2.27]"
				},
				{
					"name":"100629753 RNF11; RING finger protein 11\tK11980 RNF11; E3 ubiquitin-protein ligase RNF11"
				},
				{
					"name":"100059136 RLIM; E3 ubiquitin-protein ligase RLIM\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"100629390 E3 ubiquitin-protein ligase RLIM\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"111771522 E3 ubiquitin-protein ligase RLIM-like\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"111771538 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RLIM-like\tK16271 RLIM; E3 ubiquitin-protein ligase RLIM [EC:2.3.2.27]"
				},
				{
					"name":"100058094 RNF13; E3 ubiquitin-protein ligase RNF13 isoform X1\tK15692 RNF13; E3 ubiquitin-protein ligase RNF13 [EC:2.3.2.27]"
				},
				{
					"name":"100058790 RNF25; E3 ubiquitin-protein ligase RNF25 isoform X3\tK10640 RNF25; E3 ubiquitin-protein ligase RNF25 [EC:2.3.2.27]"
				},
				{
					"name":"100071421 RNF26; E3 ubiquitin-protein ligase RNF26\tK15693 RNF26; E3 ubiquitin-protein ligase RNF26 [EC:2.3.2.27]"
				},
				{
					"name":"100055331 RNF38; E3 ubiquitin-protein ligase RNF38 isoform X2\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"100058652 RNF44; RING finger protein 44 isoform X1\tK19041 RNF38_44; E3 ubiquitin-protein ligase RNF38\/44 [EC:2.3.2.27]"
				},
				{
					"name":"100052095 RNF41; E3 ubiquitin-protein ligase NRDP1 isoform X1\tK11981 RNF41; E3 ubiquitin-protein ligase NRDP1 [EC:2.3.2.27]"
				},
				{
					"name":"100057001 RNF43; E3 ubiquitin-protein ligase RNF43 isoform X1\tK15694 RNF43; E3 ubiquitin-protein ligase RNF43 [EC:2.3.2.27]"
				},
				{
					"name":"100052907 RNF103; E3 ubiquitin-protein ligase RNF103\tK15695 RNF103; E3 ubiquitin-protein ligase RNF103 [EC:2.3.2.27]"
				},
				{
					"name":"100054463 RNF111; E3 ubiquitin-protein ligase Arkadia\tK10635 RNF111; E3 ubiquitin-protein ligase Arkadia [EC:2.3.2.27]"
				},
				{
					"name":"100073171 RNF112; RING finger protein 112 isoform X1\tK25173 RNF112; E3 ubiquitin-protein ligase RNF112 [EC:2.3.2.27]"
				},
				{
					"name":"100071447 RNF114; E3 ubiquitin-protein ligase RNF114 isoform X1\tK15697 RNF114; E3 ubiquitin-protein ligase RNF114 [EC:2.3.2.27]"
				},
				{
					"name":"100065677 RNF115; E3 ubiquitin-protein ligase RNF115\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"100146886 RNF126; E3 ubiquitin-protein ligase RNF126\tK11982 RNF115_126; E3 ubiquitin-protein ligase RNF115\/126 [EC:2.3.2.27]"
				},
				{
					"name":"100066221 RNF121; RING finger protein 121\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"100069989 RNF175; RING finger protein 175 isoform X1\tK15698 RNF121_175; RING finger protein 121\/175"
				},
				{
					"name":"100060999 RNF122; RING finger protein 122 isoform X1\tK15699 RNF122; RING finger protein 122"
				},
				{
					"name":"100053010 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X5\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100052335 RNF125; E3 ubiquitin-protein ligase RNF125\tK12170 RNF125; E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]"
				},
				{
					"name":"100054821 RNF128; E3 ubiquitin-protein ligase RNF128 isoform X1\tK10629 RNF128; E3 ubiquitin-protein ligase RNF128 [EC:2.3.2.27]"
				},
				{
					"name":"100067162 RNF130; E3 ubiquitin-protein ligase RNF130 isoform X4\tK15701 RNF130; E3 ubiquitin-protein ligase RNF130 [EC:2.3.2.27]"
				},
				{
					"name":"102149188 RNF133; E3 ubiquitin-protein ligase RNF133\tK15702 RNF133; E3 ubiquitin-protein ligase RNF133 [EC:2.3.2.27]"
				},
				{
					"name":"100147422 RNF135; E3 ubiquitin-protein ligase RNF135\tK16272 RNF135; E3 ubiquitin-protein ligase RNF135 [EC:2.3.2.27]"
				},
				{
					"name":"100066302 RNF138; E3 ubiquitin-protein ligase RNF138 isoform X1\tK10668 RNF138; E3 ubiquitin-protein ligase RNF138 [EC:2.3.2.27]"
				},
				{
					"name":"100067392 RNF139; E3 ubiquitin-protein ligase RNF139\tK15703 RNF139; E3 ubiquitin-protein ligase RNF139 [EC:2.3.2.27]"
				},
				{
					"name":"106781589 RNF145; RING finger protein 145\tK23789 RNF145; E3 ubiquitin-protein ligase RNF145 [EC:2.3.2.27]"
				},
				{
					"name":"100067400 RNF146; E3 ubiquitin-protein ligase RNF146 isoform X1\tK15700 RNF146; E3 ubiquitin-protein ligase RNF146 [EC:2.3.2.27]"
				},
				{
					"name":"100059079 RNF149; E3 ubiquitin-protein ligase RNF149 isoform X1\tK15704 RNF149; E3 ubiquitin-protein ligase RNF149 [EC:2.3.2.27]"
				},
				{
					"name":"100050623 RNF152; E3 ubiquitin-protein ligase RNF152\tK15705 RNF152; E3 ubiquitin-protein ligase RNF152 [EC:2.3.2.27]"
				},
				{
					"name":"100059033 RNF157; E3 ubiquitin ligase RNF157 isoform X1\tK25192 RNF157; E3 ubiquitin-protein ligase RNF157 [EC:2.3.2.27]"
				},
				{
					"name":"100068804 RNF165; E3 ubiquitin-protein ligase RNF165 isoform X1\tK17821 RNF165; E3 ubiquitin-protein ligase RNF165 [EC:2.3.2.27]"
				},
				{
					"name":"100050917 RNF166; RING finger protein 166\tK17044 RNF166; E3 ubiquitin-protein ligase RNF166 [EC:2.3.2.27]"
				},
				{
					"name":"100061251 RNF167; E3 ubiquitin-protein ligase RNF167 isoform X1\tK15706 RNF167; E3 ubiquitin-protein ligase RNF167 [EC:2.3.2.27]"
				},
				{
					"name":"100053953 RNF170; E3 ubiquitin-protein ligase RNF170 isoform X1\tK15707 RNF170; E3 ubiquitin-protein ligase RNF170 [EC:2.3.2.27]"
				},
				{
					"name":"100058189 RNF180; E3 ubiquitin-protein ligase RNF180 isoform X3\tK15708 RNF180; E3 ubiquitin-protein ligase RNF180 [EC:2.3.2.27]"
				},
				{
					"name":"100053147 RNF181; E3 ubiquitin-protein ligase RNF181\tK22378 RNF181; E3 ubiquitin-protein ligase RNF181 [EC:2.3.2.27]"
				},
				{
					"name":"102149432 RNF182; E3 ubiquitin-protein ligase RNF182\tK11983 RNF182; E3 ubiquitin-protein ligase RNF182 [EC:2.3.2.27]"
				},
				{
					"name":"100071883 RNF186; RING finger protein 186\tK25214 RNF186; E3 ubiquitin-protein ligase RNF186 [EC:2.3.2.27]"
				},
				{
					"name":"102150820 RNF187; E3 ubiquitin-protein ligase RNF187\tK15709 RNF187; E3 ubiquitin-protein ligase RNF187 [EC:2.3.2.27]"
				},
				{
					"name":"100056407 RNF213; E3 ubiquitin-protein ligase RNF213 isoform X1\tK22754 RNF213; E3 ubiquitin-protein ligase RNF213 [EC:2.3.2.27]"
				},
				{
					"name":"100052861 RNF220; E3 ubiquitin-protein ligase RNF220 isoform X1\tK25174 RNF220; E3 ubiquitin-protein ligase RNF220 [EC:2.3.2.27]"
				},
				{
					"name":"100071124 RNFT1; E3 ubiquitin-protein ligase RNFT1 isoform X1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"100072218 LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNFT1\tK22379 RNFT1; E3 ubiquitin-protein ligase RNFT1 [EC:2.3.2.27]"
				},
				{
					"name":"100055300 RNFT2; RING finger and transmembrane domain-containing protein 2\tK28516 RNFT2; E3 ubiquitin-protein ligase RNFT2"
				},
				{
					"name":"100057861 SART1; U4\/U6.U5 tri-snRNP-associated protein 1 isoform X1\tK11984 SART1; U4\/U6.U5 tri-snRNP-associated protein 1"
				},
				{
					"name":"100060637 SHPRH; E3 ubiquitin-protein ligase SHPRH\tK15710 SHPRH; E3 ubiquitin-protein ligase SHPRH [EC:5.6.2.- 2.3.2.27]"
				},
				{
					"name":"100060543 SH3RF3; SH3 domain-containing RING finger protein 3 isoform X1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100061339 SH3RF1; E3 ubiquitin-protein ligase SH3RF1 isoform X1\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100071998 SH3RF2; putative E3 ubiquitin-protein ligase SH3RF2 isoform X2\tK12171 SH3RF; E3 ubiquitin-protein ligase SH3RF [EC:2.3.2.27]"
				},
				{
					"name":"100058775 HLTF; helicase-like transcription factor isoform X1\tK15711 SMARCA3; SWI\/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:5.6.2. 2.3.2.27]"
				},
				{
					"name":"100050962 SYVN1; E3 ubiquitin-protein ligase synoviolin isoform X1\tK10601 SYVN1; E3 ubiquitin-protein ligase synoviolin [EC:2.3.2.27]"
				},
				{
					"name":"100052572 TMEM129; E3 ubiquitin-protein ligase TM129\tK22380 TMEM129; E3 ubiquitin-protein ligase TM129 [EC:2.3.2.27]"
				},
				{
					"name":"100053650 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
				},
				{
					"name":"100052697 TRAIP; E3 ubiquitin-protein ligase TRAIP isoform X1\tK11985 TRAIP; TRAF-interacting protein [EC:2.3.2.27]"
				},
				{
					"name":"100060967 TTC3; E3 ubiquitin-protein ligase TTC3 isoform X1\tK15712 TTC3; E3 ubiquitin-protein ligase TTC3 [EC:2.3.2.27]"
				},
				{
					"name":"100062347 UHRF1; E3 ubiquitin-protein ligase UHRF1\tK10638 UHRF1; E3 ubiquitin-protein ligase UHRF1 [EC:2.3.2.27]"
				},
				{
					"name":"100060288 UHRF2; E3 ubiquitin-protein ligase UHRF2 isoform X1\tK15713 UHRF2; E3 ubiquitin-protein ligase UHRF2 [EC:2.3.2.27]"
				},
				{
					"name":"100068083 ZNF598; E3 ubiquitin-protein ligase ZNF598 isoform X1\tK22381 ZNF598; E3 ubiquitin-protein ligase ZNF598 [EC:2.3.2.27]"
				},
				{
					"name":"100068291 ZFP91; E3 ubiquitin-protein ligase ZFP91 isoform X1\tK25175 ZFP91; E3 ubiquitin-protein ligase ZFP91 [EC:2.3.2.27]"
				},
				{
					"name":"100068818 ZNRF1; E3 ubiquitin-protein ligase ZNRF1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"106783045 ZNRF2; E3 ubiquitin-protein ligase ZNRF2 isoform X1\tK10694 ZNRF1_2; E3 ubiquitin-protein ligase ZNRF1\/2 [EC:2.3.2.27]"
				},
				{
					"name":"100059173 ZNRF3; LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase ZNRF3\tK16273 ZNRF3; E3 ubiquitin-protein ligase ZNRF3 [EC:2.3.2.27]"
				},
				{
					"name":"111774187 ZNRF4; E3 ubiquitin-protein ligase ZNRF4\tK15715 ZNRF4; E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]"
				},
				{
					"name":"100068760 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2\tK15716 ZSWIM2; E3 ubiquitin-protein ligase ZSWIM2 [EC:2.3.2.27]"
				}
				]
			}
			]
		},
		{
			"name":"Atypical E3",
			"children":[
			{
				"name":"100062894 JADE2; E3 ubiquitin-protein ligase Jade-2 isoform X1\tK22155 JADE2; E3 ubiquitin-protein ligase Jade-2 [EC:2.3.2.27]"
			},
			{
				"name":"100068273 E4F1; transcription factor E4F1 isoform X1\tK22401 E4F1; transcription factor E4F1 \/ E3 ubiquitin-protein ligase [EC:2.3.2.27]"
			},
			{
				"name":"100066837 NSMCE1; non-structural maintenance of chromosomes element 1 homolog\tK22817 NSMCE1; non-structural maintenance of chromosomes element 1 [EC:2.3.2.27]"
			},
			{
				"name":"100051949 IRF2BPL; interferon regulatory factor 2-binding protein-like\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			},
			{
				"name":"100070974 IRF2BP1; interferon regulatory factor 2-binding protein 1\tK22383 IRF2BP; interferon regulatory factor 2-binding protein"
			}
			]
		},
		{
			"name":"UBL E3 ligases",
			"children":[
			{
				"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
			},
			{
				"name":"100053650 TOPORS; E3 ubiquitin-protein ligase Topors isoform X1\tK10631 TOPORS; E3 ubiquitin-protein ligase Topors [EC:2.3.2.27]"
			},
			{
				"name":"100060826 E3 SUMO-protein ligase RanBP2 isoform X1\tK12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]"
			},
			{
				"name":"100052741 PIAS1; E3 SUMO-protein ligase PIAS1 isoform X1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
			},
			{
				"name":"100068879 PIAS2; E3 SUMO-protein ligase PIAS2 isoform X3\tK16063 PIAS2; E3 SUMO-protein ligase PIAS2 [EC:2.3.2.-]"
			},
			{
				"name":"100065141 PIAS3; E3 SUMO-protein ligase PIAS3 isoform X1\tK16064 PIAS3; E3 SUMO-protein ligase PIAS3 [EC:2.3.2.-]"
			},
			{
				"name":"100061365 PIAS4; E3 SUMO-protein ligase PIAS4\tK16065 PIAS4; E3 SUMO-protein ligase PIAS4 [EC:2.3.2.27]"
			},
			{
				"name":"100062744 PML; protein PML isoform X1\tK10054 PML; E3 SUMO-protein ligase PML [EC:2.3.2.-]"
			},
			{
				"name":"100146225 CBX4; E3 SUMO-protein ligase CBX4\tK11452 CBX4; E3 SUMO-protein ligase CBX4 [EC:2.3.2.-]"
			},
			{
				"name":"100067659 NSMCE2; E3 SUMO-protein ligase NSE2 isoform X3\tK22756 NSMCE2; E3 SUMO-protein ligase NSE2 [EC:2.3.2.-]"
			},
			{
				"name":"102148851 RNF212; probable E3 SUMO-protein ligase RNF212 isoform X1\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"102149874 RNF212B; RING finger protein 212B isoform X1\tK25662 RNF212; E3 SUMO-protein ligase RNF212 [EC:2.3.2.-]"
			},
			{
				"name":"100146234 ZBED1; zinc finger BED domain-containing protein 1\tK24637 ZBED1; zinc finger BED domain-containing protein 1 (E3 SUMO-protein ligase ZBED1) [EC:2.3.2.-]"
			},
			{
				"name":"100070011 ZNF451; E3 SUMO-protein ligase ZNF451 isoform X1\tK25176 ZNF451; E3 SUMO-protein ligase ZNF451 [EC:2.3.2.-]"
			},
			{
				"name":"100063706 HERC6; probable E3 ubiquitin-protein ligase HERC6 isoform X4\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"100063774 HERC5; E3 ISG15--protein ligase HERC5 isoform X1\tK22372 HERC5_6; E3 ISG15--protein ligase [EC:2.3.2.-]"
			},
			{
				"name":"100065945 UFL1; E3 UFM1-protein ligase 1\tK22755 UFL1; E3 UFM1-protein ligase 1 [EC:2.3.2.-]"
			},
			{
				"name":"100066587 DCUN1D1; DCN1-like protein 1 isoform X3\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"100067313 DCUN1D2; DCN1-like protein 2 isoform X1\tK17822 DCUN1D1_2; DCN1-like protein 1\/2"
			},
			{
				"name":"100058079 DCUN1D3; DCN1-like protein 3\tK17823 DCUN1D3; DCN1-like protein 3"
			},
			{
				"name":"100060668 DCUN1D4; DCN1-like protein 4 isoform X2\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			},
			{
				"name":"100069130 DCUN1D5; DCN1-like protein 5 isoform X1\tK17824 DCUN1D4_5; DCN1-like protein 4\/5"
			}
			]
		},
		{
			"name":"Multi subunit type E3",
			"children":[
			{
				"name":"SCF complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100051217 CUL1; cullin-1\tK03347 CUL1; cullin 1"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"100062946 SKP1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (F-box)",
					"children":[
					{
						"name":"100069972 FBXW11; F-box\/WD repeat-containing protein 11 isoform X3\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"100070200 BTRC; F-box\/WD repeat-containing protein 1A isoform X1\tK03362 FBXW1_11; F-box and WD-40 domain protein 1\/11"
					},
					{
						"name":"100067698 FBXW2; F-box\/WD repeat-containing protein 2\tK10261 FBXW2; F-box and WD-40 domain protein 2"
					},
					{
						"name":"100070086 FBXW4; F-box\/WD repeat-containing protein 4 isoform X1\tK10262 FBXW4; F-box and WD-40 domain protein 4"
					},
					{
						"name":"100067988 FBXW5; F-box\/WD repeat-containing protein 5 isoform X2\tK10263 FBXW5; F-box and WD-40 domain protein 5"
					},
					{
						"name":"100062294 FBXW7; F-box\/WD repeat-containing protein 7\tK10260 FBXW7; F-box and WD-40 domain protein 7"
					},
					{
						"name":"100055213 FBXW8; F-box\/WD repeat-containing protein 8 isoform X1\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					},
					{
						"name":"100064271 FBXW9; F-box\/WD repeat-containing protein 9 isoform X1\tK10265 FBXW9; F-box and WD-40 domain protein 9"
					},
					{
						"name":"100073136 CDRT1; CMT1A duplicated region transcript 1 protein isoform X1\tK10266 FBXW10; F-box and WD-40 domain protein 10"
					},
					{
						"name":"102150555 FBXW12; LOW QUALITY PROTEIN: F-box\/WD repeat-containing protein 12\tK10267 FBXW12S; F-box and WD-40 domain protein 12\/13\/14\/15\/16\/17\/19"
					},
					{
						"name":"100053697 SKP2; S-phase kinase-associated protein 2 isoform X1\tK03875 SKP2; F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2)"
					},
					{
						"name":"100056080 FBXL2; F-box\/LRR-repeat protein 2 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"100068335 FBXL20; F-box\/LRR-repeat protein 20 isoform X1\tK10268 FBXL2_20; F-box and leucine-rich repeat protein 2\/20"
					},
					{
						"name":"100052811 FBXL3; F-box\/LRR-repeat protein 3\tK10269 FBXL3; F-box and leucine-rich repeat protein 3"
					},
					{
						"name":"100066051 FBXL4; F-box\/LRR-repeat protein 4\tK10270 FBXL4; F-box and leucine-rich repeat protein 4"
					},
					{
						"name":"100055895 FBXL5; F-box\/LRR-repeat protein 5 isoform X5\tK10271 FBXL5; F-box and leucine-rich repeat protein 5"
					},
					{
						"name":"100147644 FBXL6; F-box\/LRR-repeat protein 6 isoform X2\tK10272 FBXL6; F-box and leucine-rich repeat protein 6"
					},
					{
						"name":"100070113 FBXL7; F-box\/LRR-repeat protein 7 isoform X2\tK10273 FBXL7; F-box and leucine-rich repeat protein 7"
					},
					{
						"name":"100052927 FBXL8; F-box\/LRR-repeat protein 8\tK10274 FBXL8; F-box and leucine-rich repeat protein 8"
					},
					{
						"name":"102149450 LRRC29; LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 29\tK10275 FBXL9; F-box and leucine-rich repeat protein 9"
					},
					{
						"name":"100052955 KDM2A; lysine-specific demethylase 2A isoform X2\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"100059690 KDM2B; lysine-specific demethylase 2B isoform X1\tK10276 FBXL10_11; F-box and leucine-rich repeat protein 10\/11 [EC:1.14.11.27]"
					},
					{
						"name":"100058712 FBXL12; F-box\/LRR-repeat protein 12 isoform X2\tK10278 FBXL12; F-box and leucine-rich repeat protein 12"
					},
					{
						"name":"100058236 FBXL13; F-box\/LRR-repeat protein 13 isoform X1\tK10279 FBXL13; dynein regulatory complex subunit 6"
					},
					{
						"name":"102148197 FBXL14; F-box\/LRR-repeat protein 14 isoform X1\tK10280 FBXL14; F-box and leucine-rich repeat protein 14"
					},
					{
						"name":"100069952 FBXL15; F-box\/LRR-repeat protein 15 isoform X1\tK10281 FBXL15; F-box and leucine-rich repeat protein 15"
					},
					{
						"name":"100147621 FBXL16; F-box\/LRR-repeat protein 16\tK10282 FBXL16; F-box and leucine-rich repeat protein 16"
					},
					{
						"name":"100146140 FBXL17; F-box\/LRR-repeat protein 17\tK10283 FBXL17; F-box and leucine-rich repeat protein 17"
					},
					{
						"name":"100063588 FBXL19; F-box\/LRR-repeat protein 19 isoform X2\tK10285 FBXL19; F-box and leucine-rich repeat protein 19"
					},
					{
						"name":"100062673 FBXL21; F-box\/LRR-repeat protein 21\tK10287 FBXL21; F-box and leucine-rich repeat protein 21"
					},
					{
						"name":"100053985 FBXL22; F-box and leucine-rich protein 22\tK10288 FBXL22; F-box and leucine-rich repeat protein 22"
					},
					{
						"name":"100068378 CCNF; cyclin-F\tK10289 CCNF; F-box protein 1 (cyclin F)"
					},
					{
						"name":"100051196 FBXO2; F-box only protein 2 isoform X2\tK10099 FBXO2; F-box protein 2"
					},
					{
						"name":"100059295 FBXO3; F-box only protein 3\tK10290 FBXO3; F-box protein 3"
					},
					{
						"name":"100065773 FBXO4; F-box only protein 4 isoform X1\tK10291 FBXO4; F-box protein 4"
					},
					{
						"name":"100062649 FBXO5; F-box only protein 5 isoform X1\tK10292 FBXO5; F-box protein 5"
					},
					{
						"name":"100056376 FBXO6; F-box only protein 6 isoform X3\tK10100 FBXO6; F-box protein 6"
					},
					{
						"name":"100068847 FBXO7; F-box only protein 7 isoform X2\tK10293 FBXO7; F-box protein 7"
					},
					{
						"name":"100061095 FBXO8; F-box only protein 8\tK10294 FBXO8; F-box protein 8"
					},
					{
						"name":"100069351 FBXO9; F-box only protein 9\tK10295 FBXO9; F-box protein 9"
					},
					{
						"name":"100066495 FBXO10; F-box only protein 10 isoform X1\tK10296 FBXO10; F-box protein 10"
					},
					{
						"name":"100053097 FBXO11; F-box only protein 11 isoform X1\tK10297 FBXO11; F-box protein 11"
					},
					{
						"name":"100061530 FBXO15; F-box only protein 15 isoform X4\tK10298 FBXO15; F-box protein 15"
					},
					{
						"name":"100061112 FBXO16; F-box only protein 16 isoform X1\tK10299 FBXO16; F-box protein 16"
					},
					{
						"name":"100066608 FBXO17; F-box only protein 17\tK10101 FBXO17; F-box protein 17"
					},
					{
						"name":"100070322 FBXO18; F-box DNA helicase 1 isoform X1\tK10300 FBH1; F-box DNA helicase 1 [EC:5.6.2.4]"
					},
					{
						"name":"100052118 LMO7; LIM domain only protein 7 isoform X9\tK06084 LMO7; F-box protein 20"
					},
					{
						"name":"100055074 FBXO21; F-box only protein 21 isoform X1\tK10301 FBXO21; F-box protein 21"
					},
					{
						"name":"100050726 FBXO22; F-box only protein 22 isoform X2\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"100056207 F-box only protein 22\tK10302 FBXO22; F-box protein 22"
					},
					{
						"name":"100146751 TSPAN17; tetraspanin-17 isoform X1\tK10303 FBXO23; F-box protein 23"
					},
					{
						"name":"100067395 FBXO24; F-box only protein 24 isoform X1\tK10304 FBXO24; F-box protein 24"
					},
					{
						"name":"100051951 FBXO25; F-box only protein 25 isoform X1\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"100057506 FBXO32; F-box only protein 32\tK10305 FBXO25_32; F-box protein 25\/32"
					},
					{
						"name":"100066651 FBXO27; F-box only protein 27 isoform X1\tK10102 FBXO27; F-box protein 27"
					},
					{
						"name":"100054130 FBXO28; F-box only protein 28\tK10306 FBXO28; F-box protein 28"
					},
					{
						"name":"100066297 FBXO30; F-box only protein 30 isoform X1\tK10307 FBXO30; F-box protein 30"
					},
					{
						"name":"100070571 FBXO31; F-box only protein 31 isoform X1\tK10308 FBXO31; F-box protein 31"
					},
					{
						"name":"100061051 FBXO33; F-box only protein 33\tK10310 FBXO33; F-box protein 33"
					},
					{
						"name":"102148298 FBXO34; F-box only protein 34 isoform X1\tK10311 FBXO34; F-box protein 34"
					},
					{
						"name":"100063340 FBXO36; F-box only protein 36 isoform X1\tK10312 FBXO36; F-box protein 36"
					},
					{
						"name":"100060728 FBXO38; F-box only protein 38 isoform X1\tK10313 FBXO38; F-box protein 38"
					},
					{
						"name":"100072742 FBXO39; F-box only protein 39\tK10314 FBXO39; F-box protein 39"
					},
					{
						"name":"100070778 FBXO40; F-box only protein 40\tK10315 FBXO40; F-box protein 40"
					},
					{
						"name":"100059038 FBXO41; F-box only protein 41\tK10316 FBXO41; F-box protein 41"
					},
					{
						"name":"100053402 FBXO42; F-box only protein 42\tK10317 FBXO42; F-box protein 42"
					},
					{
						"name":"100056417 uncharacterized protein LOC100056417 isoform X1\tK10103 FBXO44; F-box protein 44"
					},
					{
						"name":"100069808 FBXO45; F-box\/SPRY domain-containing protein 1\tK10319 FBXO45; F-box protein 45"
					},
					{
						"name":"100065741 FBXO46; F-box only protein 46\tK10320 FBXO46; F-box protein 46"
					},
					{
						"name":"100068413 FBXO47; F-box only protein 47 isoform X1\tK10321 FBXO47; F-box protein 47"
					},
					{
						"name":"100050965 FBXO48; F-box only protein 48\tK27313 FBXO48; F-box protein 48"
					}
					]
				}
				]
			},
			{
				"name":"Cul2 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100054982 CUL2; cullin-2\tK03870 CUL2; cullin 2"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100060902 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"106781563 ELOB; elongin-B isoform X1\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100058139 VHL; von Hippel-Lindau disease tumor suppressor\tK03871 VHL; von Hippel-Lindau disease tumor supressor"
					},
					{
						"name":"100065715 LRR1; leucine-rich repeat protein 1 isoform X1\tK10348 LRR1; LRR-repeat protein 1"
					},
					{
						"name":"100064222 FEM1C; protein fem-1 homolog C\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"102148897 FEM1A; protein fem-1 homolog A\tK25805 FEM1A_C; protein fem-1 homolog A\/C"
					},
					{
						"name":"100052688 FEM1B; protein fem-1 homolog B isoform X1\tK10349 FEM1B; protein fem-1 homolog B"
					},
					{
						"name":"100071336 APPBP2; amyloid protein-binding protein 2\tK25806 APPBP2; amyloid protein-binding protein 2"
					},
					{
						"name":"100065865 KLHDC2; kelch domain-containing protein 2\tK25807 KLHDC2; kelch domain-containing protein 2"
					},
					{
						"name":"100067213 KLHDC3; kelch domain-containing protein 3\tK25808 KLHDC3; kelch domain-containing protein 3"
					},
					{
						"name":"100057051 KLHDC10; kelch domain-containing protein 10\tK25809 KLHDC10; kelch domain-containing protein 10"
					},
					{
						"name":"100061512 ZYG11A; protein zyg-11 homolog A isoform X1\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100061587 ZYG11B; protein zyg-11 homolog B isoform X3\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100066859 ZER1; protein zer-1 homolog isoform X1\tK10350 ZYG11; Zyg-11 protein"
					},
					{
						"name":"100064078 ZSWIM8; zinc finger SWIM domain-containing protein 8 isoform X3\tK25207 ZSWIM8; zinc finger SWIM domain-containing protein 8"
					},
					{
						"name":"100061889 melanoma antigen preferentially expressed in tumors isoform X1\tK28155 PRAME; melanoma antigen preferentially expressed in tumors"
					}
					]
				}
				]
			},
			{
				"name":"Cul3 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100061420 CUL3; cullin-3 isoform X1\tK03869 CUL3; cullin 3"
					}
					]
				},
				{
					"name":"Adoptor and target recognizing subunit (BTB)",
					"children":[
					{
						"name":"100064472 KLHL5; kelch-like protein 5 isoform X1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100065536 KLHL1; kelch-like protein 1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100071689 KLHL4; kelch-like protein 4 isoform X1\tK10442 KLHL1_4_5; kelch-like protein 1\/4\/5"
					},
					{
						"name":"100062564 KLHL3; kelch-like protein 3 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"100068150 KLHL2; kelch-like protein 2 isoform X1\tK10443 KLHL2_3; kelch-like protein 2\/3"
					},
					{
						"name":"100058733 KLHL6; kelch-like protein 6\tK10444 KLHL6; kelch-like protein 6"
					},
					{
						"name":"100053660 KLHL7; kelch-like protein 7 isoform X1\tK10445 KLHL7; kelch-like protein 7"
					},
					{
						"name":"100062841 KLHL8; kelch-like protein 8 isoform X1\tK10446 KLHL8; kelch-like protein 8"
					},
					{
						"name":"100053772 KLHL13; kelch-like protein 13 isoform X2\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"100064784 KLHL9; kelch-like protein 9\tK10447 KLHL9_13; kelch-like protein 9\/13"
					},
					{
						"name":"100053248 KLHL10; kelch-like protein 10 isoform X1\tK10448 KLHL10; kelch-like protein 10"
					},
					{
						"name":"100066456 KLHL11; kelch-like protein 11\tK10449 KLHL11; kelch-like protein 11"
					},
					{
						"name":"100052378 KLHL12; kelch-like protein 12\tK10450 KLHL12; kelch-like protein 12"
					},
					{
						"name":"100052448 KLHL14; kelch-like protein 14\tK10451 KLHL14; kelch-like protein 14"
					},
					{
						"name":"100052043 KLHL15; kelch-like protein 15\tK10452 KLHL15; kelch-like protein 15"
					},
					{
						"name":"100069891 GAN; gigaxonin isoform X1\tK10453 KLHL16; kelch-like protein 16 (gigaxonin)"
					},
					{
						"name":"100146295 KLHL17; kelch-like protein 17 isoform X1\tK10454 KLHL17; kelch-like protein 17 (actinfilin)"
					},
					{
						"name":"100064728 KLHL18; kelch-like protein 18 isoform X6\tK10455 KLHL18; kelch-like protein 18"
					},
					{
						"name":"100055128 KEAP1; kelch-like ECH-associated protein 1\tK10456 KLHL19; kelch-like protein 19"
					},
					{
						"name":"100060895 KLHL20; kelch-like protein 20 isoform X1\tK10457 KLHL20; kelch-like protein 20"
					},
					{
						"name":"100059160 KLHL21; kelch-like protein 21\tK10458 KLHL21; kelch-like protein 21"
					},
					{
						"name":"100049928 KLHL22; kelch-like protein 22\tK10459 KLHL22; kelch-like protein 22"
					},
					{
						"name":"100052649 KLHL23; kelch-like protein 23\tK10460 KLHL23; kelch-like protein 23"
					},
					{
						"name":"100058815 KLHL24; kelch-like protein 24 isoform X1\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"100064622 KLHL35; kelch-like protein 35\tK10461 KLHL24_35; kelch-like protein 24\/35"
					},
					{
						"name":"100054132 KLHL25; kelch-like protein 25\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"100073290 ENC1; ectoderm-neural cortex protein 1\tK10462 KLHL25_37; kelch-like protein 25\/37 (ectoderm-neural cortex protein)"
					},
					{
						"name":"106780892 KLHL26; kelch-like protein 26 isoform X1\tK10463 KLHL26; kelch-like protein 26"
					},
					{
						"name":"100052181 IPP; actin-binding protein IPP isoform X1\tK13956 IPP; actin-binding protein IPP"
					},
					{
						"name":"100063556 KLHL28; kelch-like protein 28\tK10464 KLHL28; kelch-like protein 28"
					},
					{
						"name":"100071687 KLHL29; kelch-like protein 29\tK10465 KLHL29; kelch-like protein 29"
					},
					{
						"name":"100057618 KLHL30; kelch-like protein 30\tK10466 KLHL30; kelch-like protein 30"
					},
					{
						"name":"100069486 KLHL31; kelch-like protein 31\tK10467 KLHL31; kelch-like protein 31"
					},
					{
						"name":"100065998 KLHL32; kelch-like protein 32 isoform X1\tK10468 KLHL32; kelch-like protein 32"
					},
					{
						"name":"100072582 KLHL33; kelch-like protein 33\tK13957 KLHL33; kelch-like protein 33"
					},
					{
						"name":"100147609 KLHL34; kelch-like protein 34\tK10469 KLHL34; kelch-like protein 34"
					},
					{
						"name":"100056052 KLHL36; kelch-like protein 36\tK13958 KLHL36; kelch-like protein 36"
					},
					{
						"name":"100067152 KLHL38; kelch-like protein 38\tK13959 KLHL38; kelch-like protein 38"
					},
					{
						"name":"100069196 KLHL42; kelch-like protein 42\tK27973 KLHL42; kelch-like protein 42"
					},
					{
						"name":"100055296 KBTBD2; kelch repeat and BTB domain-containing protein 2\tK10470 KBTBD2; kelch repeat and BTB domain-containing protein 2"
					},
					{
						"name":"100061596 KBTBD3; kelch repeat and BTB domain-containing protein 3\tK10471 KBTBD3; kelch repeat and BTB domain-containing protein 3"
					},
					{
						"name":"100051681 KBTBD4; kelch repeat and BTB domain-containing protein 4 isoform X2\tK10472 KBTBD4; kelch repeat and BTB domain-containing protein 4"
					},
					{
						"name":"100052537 KLHL41; kelch-like protein 41\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"100067358 KLHL40; kelch-like protein 40\tK10473 KBTBD5_10; kelch repeat and BTB domain-containing protein 5\/10"
					},
					{
						"name":"100061221 KBTBD7; kelch repeat and BTB domain-containing protein 7\tK10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6\/7"
					},
					{
						"name":"100061256 KBTBD6; kelch repeat and BTB domain-containing protein 6\tK10474 KBTBD6_7; kelch repeat and BTB domain-containing protein 6\/7"
					},
					{
						"name":"100064087 KBTBD8; kelch repeat and BTB domain-containing protein 8 isoform X1\tK10475 KBTBD8; kelch repeat and BTB domain-containing protein 8"
					},
					{
						"name":"111770964 kelch repeat and BTB domain-containing protein 11-like\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"111770969 kelch repeat and BTB domain-containing protein 11-like\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"111771768 kelch repeat and BTB domain-containing protein 11-like\tK10476 KBTBD11; kelch repeat and BTB domain-containing protein 11"
					},
					{
						"name":"100053890 KBTBD12; kelch repeat and BTB domain-containing protein 12\tK21912 KBTBD12; kelch repeat and BTB domain-containing protein 12"
					},
					{
						"name":"100066512 KBTBD13; kelch repeat and BTB domain-containing protein 13\tK21913 KBTBD13; kelch repeat and BTB domain-containing protein 13"
					},
					{
						"name":"100068143 BTBD1; BTB\/POZ domain-containing protein 1 isoform X1\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"100068599 BTBD2; LOW QUALITY PROTEIN: BTB\/POZ domain-containing protein 2\tK10477 BTBD1_2; BTB\/POZ domain-containing protein 1\/2"
					},
					{
						"name":"100063893 BTBD3; BTB\/POZ domain-containing protein 3 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"102150846 BTBD6; BTB\/POZ domain-containing protein 6 isoform X1\tK10478 BTBD3_6; BTB\/POZ domain-containing protein 3\/6"
					},
					{
						"name":"100053454 BTBD7; BTB\/POZ domain-containing protein 7\tK10479 BTBD7; BTB\/POZ domain-containing protein 7"
					},
					{
						"name":"100060067 uncharacterized protein KIAA1107 homolog isoform X2\tK10480 BTBD8; BTB\/POZ domain-containing protein 8"
					},
					{
						"name":"100065100 BTBD9; BTB\/POZ domain-containing protein 9\tK10481 BTBD9; BTB\/POZ domain-containing protein 9"
					},
					{
						"name":"100056058 BTBD10; BTB\/POZ domain-containing protein 10 isoform X2\tK10482 BTBD10; BTB\/POZ domain-containing protein 10"
					},
					{
						"name":"100054002 BTBD11; ankyrin repeat and BTB\/POZ domain-containing protein BTBD11 isoform X1\tK10483 BTBD11; BTB\/POZ domain-containing protein 11"
					},
					{
						"name":"100069533 SLX4; structure-specific endonuclease subunit SLX4 isoform X1\tK10484 BTBD12; structure-specific endonuclease subunit SLX4 (BTB\/POZ domain-containing protein 12)"
					},
					{
						"name":"100060991 GMCL1; germ cell-less protein-like 1\tK10485 BTBD13; BTB\/POZ domain-containing protein 13 (germ cell-less protein-like 1)"
					},
					{
						"name":"100063244 NACC1; nucleus accumbens-associated protein 1\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"100066292 NACC2; nucleus accumbens-associated protein 2\tK10486 BTBD14; BTB\/POZ domain-containing protein 14"
					},
					{
						"name":"100064634 BTBD16; BTB\/POZ domain-containing protein 16 isoform X1\tK10487 BTBD16; BTB\/POZ domain-containing protein 16"
					},
					{
						"name":"100052254 ZBTB1; zinc finger and BTB domain-containing protein 1 isoform X1\tK10488 ZBTB1; zinc finger and BTB domain-containing protein 1"
					},
					{
						"name":"100060294 ZBTB2; zinc finger and BTB domain-containing protein 2\tK10489 ZBTB2; zinc finger and BTB domain-containing protein 2"
					},
					{
						"name":"100060251 ZBTB3; zinc finger and BTB domain-containing protein 3\tK10490 ZBTB3; zinc finger and BTB domain-containing protein 3"
					},
					{
						"name":"100072244 LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 3-like\tK10490 ZBTB3; zinc finger and BTB domain-containing protein 3"
					},
					{
						"name":"100072993 ZBTB4; zinc finger and BTB domain-containing protein 4\tK10491 ZBTB4; zinc finger and BTB domain-containing protein 4"
					},
					{
						"name":"100067456 ZBTB6; zinc finger and BTB domain-containing protein 6\tK10493 ZBTB6; zinc finger and BTB domain-containing protein 6"
					},
					{
						"name":"100053521 ZBTB7C; zinc finger and BTB domain-containing protein 7C\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"100057144 ZBTB7B; zinc finger and BTB domain-containing protein 7B isoform X1\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"111774178 ZBTB7A; LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 7A\tK10494 ZBTB7; zinc finger and BTB domain-containing protein 7"
					},
					{
						"name":"100055796 ZBTB8A; zinc finger and BTB domain-containing protein 8A isoform X1\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"100630269 ZBTB8B; zinc finger and BTB domain-containing protein 8B\tK10495 ZBTB8; zinc finger and BTB domain-containing protein 8"
					},
					{
						"name":"100061718 ZBTB9; zinc finger and BTB domain-containing protein 9\tK10496 ZBTB9; zinc finger and BTB domain-containing protein 9"
					},
					{
						"name":"100050624 ZBTB10; zinc finger and BTB domain-containing protein 10\tK10497 ZBTB10; zinc finger and BTB domain-containing protein 10"
					},
					{
						"name":"100072181 ZBTB11; zinc finger and BTB domain-containing protein 11 isoform X1\tK10498 ZBTB11; zinc finger and BTB domain-containing protein 11"
					},
					{
						"name":"100147476 ZBTB12; zinc finger and BTB domain-containing protein 12\tK10499 ZBTB12; zinc finger and BTB domain-containing protein 12"
					},
					{
						"name":"100062269 ZBTB16; zinc finger and BTB domain-containing protein 16\tK10055 ZBTB16; zinc finger and BTB domain-containing protein 16"
					},
					{
						"name":"100050436 ZBTB17; zinc finger and BTB domain-containing protein 17 isoform X2\tK10500 ZBTB17; zinc finger and BTB domain-containing protein 17"
					},
					{
						"name":"100052918 ZBTB22; zinc finger and BTB domain-containing protein 22\tK10502 ZBTB22; zinc finger and BTB domain-containing protein 22"
					},
					{
						"name":"100066674 ZBTB24; zinc finger and BTB domain-containing protein 24 isoform X1\tK10503 ZBTB24; zinc finger and BTB domain-containing protein 24"
					},
					{
						"name":"100052189 ZBTB25; zinc finger and BTB domain-containing protein 25 isoform X1\tK10504 ZBTB25; zinc finger and BTB domain-containing protein 25"
					},
					{
						"name":"100067432 ZBTB26; zinc finger and BTB domain-containing protein 26\tK10505 ZBTB26; zinc finger and BTB domain-containing protein 26"
					},
					{
						"name":"100059770 ZBTB32; zinc finger and BTB domain-containing protein 32\tK10506 ZBTB32; zinc finger and BTB domain-containing protein 32"
					},
					{
						"name":"100062002 ZBTB33; transcriptional regulator Kaiso isoform X1\tK10507 ZBTB33; zinc finger and BTB domain-containing protein 33"
					},
					{
						"name":"100070589 ZBTB34; zinc finger and BTB domain-containing protein 34\tK10508 ZBTB34; zinc finger and BTB domain-containing protein 34"
					},
					{
						"name":"100061135 ZBTB37; zinc finger and BTB domain-containing protein 37\tK10509 ZBTB37; zinc finger and BTB domain-containing protein 37"
					},
					{
						"name":"100051476 ZBTB38; zinc finger and BTB domain-containing protein 38\tK10510 ZBTB38; zinc finger and BTB domain-containing protein 38"
					},
					{
						"name":"100049990 ZBTB39; zinc finger and BTB domain-containing protein 39\tK10511 ZBTB39; zinc finger and BTB domain-containing protein 39"
					},
					{
						"name":"100058142 ZBTB40; zinc finger and BTB domain-containing protein 40\tK10512 ZBTB40; zinc finger and BTB domain-containing protein 40"
					},
					{
						"name":"100051497 ZBTB41; zinc finger and BTB domain-containing protein 41\tK10513 ZBTB41; zinc finger and BTB domain-containing protein 41"
					},
					{
						"name":"100067188 ZBTB43; zinc finger and BTB domain-containing protein 43\tK10514 ZBTB43; zinc finger and BTB domain-containing protein 43"
					},
					{
						"name":"100064712 ZBTB44; zinc finger and BTB domain-containing protein 44 isoform X1\tK10515 ZBTB44; zinc finger and BTB domain-containing protein 44"
					},
					{
						"name":"100147405 ZBTB45; zinc finger and BTB domain-containing protein 45\tK10516 ZBTB45; zinc finger and BTB domain-containing protein 45"
					},
					{
						"name":"100051559 ZBTB46; zinc finger and BTB domain-containing protein 46 isoform X1\tK10517 ZBTB46; zinc finger and BTB domain-containing protein 46"
					},
					{
						"name":"100067380 ZBTB47; zinc finger and BTB domain-containing protein 47 isoform X1\tK10518 ZBTB47; zinc finger and BTB domain-containing protein 47"
					},
					{
						"name":"100059238 ZBTB48; telomere zinc finger-associated protein isoform X1\tK10519 ZBTB48; zinc finger and BTB domain-containing protein 48"
					},
					{
						"name":"100049815 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1 isoform X1\tK10520 ABTB1; ankyrin repeat and BTB\/POZ domain-containing protein 1"
					},
					{
						"name":"100060581 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2 isoform X1\tK10521 ABTB2; ankyrin repeat and BTB\/POZ domain-containing protein 2"
					},
					{
						"name":"100057764 RHOBTB2; rho-related BTB domain-containing protein 2 isoform X3\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"100062805 RHOBTB1; rho-related BTB domain-containing protein 1 isoform X3\tK07868 RHOBTB1_2; Rho-related BTB domain-containing protein 1\/2"
					},
					{
						"name":"100073227 RHOBTB3; rho-related BTB domain-containing protein 3\tK07869 RHOBTB3; Rho-related BTB domain-containing protein 3"
					},
					{
						"name":"100058953 TNFAIP1; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 isoform X2\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100065972 KCTD13; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 isoform X1\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100066665 KCTD10; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3\tK15074 BACURD; BTB\/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein"
					},
					{
						"name":"100050071 KCTD15; BTB\/POZ domain-containing protein KCTD15\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"100064531 KCTD1; BTB\/POZ domain-containing protein KCTD1 isoform X3\tK21754 KCTD1_15; BTB\/POZ domain-containing protein KCTD1\/15"
					},
					{
						"name":"100060086 KCTD2; BTB\/POZ domain-containing protein KCTD2\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100068494 KCTD5; BTB\/POZ domain-containing protein KCTD5 isoform X1\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100630683 KCTD17; BTB\/POZ domain-containing protein KCTD17 isoform X1\tK21914 KCTD2_5_17; BTB\/POZ domain-containing protein KCTD2\/5\/17"
					},
					{
						"name":"100057376 KCTD3; BTB\/POZ domain-containing protein KCTD3 isoform X3\tK21915 KCTD3; BTB\/POZ domain-containing protein KCTD3"
					},
					{
						"name":"100050505 KCTD6; BTB\/POZ domain-containing protein KCTD6 isoform X1\tK21916 KCTD6; BTB\/POZ domain-containing protein KCTD6"
					},
					{
						"name":"100063019 KCTD14; BTB\/POZ domain-containing protein KCTD14\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"100147567 KCTD7; BTB\/POZ domain-containing protein KCTD7 isoform X1\tK21917 KCTD7_14; BTB\/POZ domain-containing protein KCTD7\/14"
					},
					{
						"name":"100062435 KCTD8; BTB\/POZ domain-containing protein KCTD8\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"100072042 KCTD16; BTB\/POZ domain-containing protein KCTD16\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"111768608 KCTD12; BTB\/POZ domain-containing protein KCTD12\tK21918 KCTD8_12_16; BTB\/POZ domain-containing protein KCTD8\/12\/16"
					},
					{
						"name":"100059300 KCTD9; BTB\/POZ domain-containing protein KCTD9\tK21919 KCTD9; BTB\/POZ domain-containing protein KCTD9"
					},
					{
						"name":"100147121 KCTD11; BTB\/POZ domain-containing protein KCTD11\tK21920 KCTD11; BTB\/POZ domain-containing protein KCTD11 [EC:2.3.2.27]"
					},
					{
						"name":"100070939 KCTD18; BTB\/POZ domain-containing protein KCTD18\tK21921 KCTD18; BTB\/POZ domain-containing protein KCTD18"
					},
					{
						"name":"100062932 KCTD21; BTB\/POZ domain-containing protein KCTD21\tK21922 KCTD21; BTB\/POZ domain-containing protein KCTD21"
					},
					{
						"name":"100058709 DIABLO; diablo homolog, mitochondrial isoform X1\tK10522 DIABLO; diablo"
					},
					{
						"name":"100056116 SPOP; speckle-type POZ protein isoform X1\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"100056551 SPOPL; speckle-type POZ protein-like isoform X1\tK10523 SPOP; speckle-type POZ protein"
					},
					{
						"name":"100050778 LZTR1; leucine-zipper-like transcriptional regulator 1 isoform X1\tK23330 LZTR1; leucine-zipper-like transcriptional regulator 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul4 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100033930 CUL4A; cullin-4A\tK10609 CUL4; cullin 4"
					},
					{
						"name":"100033938 CUL4B; cullin-4B isoform X3\tK10609 CUL4; cullin 4"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100059606 DDB1; DNA damage-binding protein 1\tK10610 DDB1; DNA damage-binding protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit (DCAF)",
					"children":[
					{
						"name":"100051180 DDB2; DNA damage-binding protein 2 isoform X1\tK10140 DDB2; DNA damage-binding protein 2"
					},
					{
						"name":"100051199 ERCC8; DNA excision repair protein ERCC-8 isoform X1\tK10570 ERCC8; DNA excision repair protein ERCC-8"
					},
					{
						"name":"100053984 DET1; DET1 homolog isoform X1\tK10571 DET1; de-etiolated-1"
					},
					{
						"name":"100061855 COP1; E3 ubiquitin-protein ligase RFWD2 isoform X1\tK10143 RFWD2; E3 ubiquitin-protein ligase RFWD2 [EC:2.3.2.27]"
					},
					{
						"name":"100630400 DDA1; DET1- and DDB1-associated protein 1\tK11792 DDA1; DET1- and DDB1-associated protein 1"
					},
					{
						"name":"100052958 CRBN; protein cereblon isoform X1\tK11793 CRBN; cereblon"
					},
					{
						"name":"100629233 torsin-1A-interacting protein 2\tK11794 IFRG15; IFRG15 protein"
					},
					{
						"name":"100069434 TRPC4AP; short transient receptor potential channel 4-associated protein isoform X1\tK11796 TRPC4AP; Trpc4-associated protein"
					},
					{
						"name":"100061218 DCAF1; DDB1- and CUL4-associated factor 1 isoform X1\tK11789 DCAF1; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
					},
					{
						"name":"100054533 DTL; denticleless protein homolog isoform X1\tK11790 DTL; denticleless"
					},
					{
						"name":"100050032 DCAF4; DDB1- and CUL4-associated factor 4 isoform X1\tK11799 DCAF4; DDB1- and CUL4-associated factor 4"
					},
					{
						"name":"100063741 DCAF5; DDB1- and CUL4-associated factor 5 isoform X1\tK11800 DCAF5; DDB1- and CUL4-associated factor 5"
					},
					{
						"name":"100057094 DCAF6; DDB1- and CUL4-associated factor 6 isoform X1\tK11795 DCAF6; DDB1- and CUL4-associated factor 6"
					},
					{
						"name":"100054273 DCAF7; DDB1- and CUL4-associated factor 7\tK11805 DCAF7; DDB1- and CUL4-associated factor 7"
					},
					{
						"name":"100053669 DCAF8; DDB1- and CUL4-associated factor 8 isoform X1\tK11804 DCAF8; DDB1- and CUL4-associated factor 8"
					},
					{
						"name":"100056964 WDTC1; WD and tetratricopeptide repeats protein 1 isoform X1\tK11807 WDTC1; WD and tetratricopeptide repeats protein 1"
					},
					{
						"name":"100066214 DCAF10; DDB1- and CUL4-associated factor 10 isoform X1\tK11802 DCAF10; DDB1- and CUL4-associated factor 10"
					},
					{
						"name":"100051911 DCAF11; DDB1- and CUL4-associated factor 11 isoform X1\tK11801 DCAF11; DDB1- and CUL4-associated factor 11"
					},
					{
						"name":"100059984 DCAF12L2; DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100060012 DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100068462 DCAF12; DDB1- and CUL4-associated factor 12 isoform X1\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"111771542 DCAF12L2; LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"111771735 DDB1- and CUL4-associated factor 12-like protein 2\tK11803 DCAF12; DDB1- and CUL4-associated factor 12"
					},
					{
						"name":"100062586 DCAF13; DDB1- and CUL4-associated factor 13\tK11806 DCAF13; DDB1- and CUL4-associated factor 13"
					},
					{
						"name":"100069267 PHIP; PH-interacting protein isoform X1\tK11797 PHIP; PH-interacting protein"
					},
					{
						"name":"100147630 DCAF15; DDB1- and CUL4-associated factor 15\tK11791 DCAF15; DDB1- and CUL4-associated factor 15"
					},
					{
						"name":"100055762 DCAF16; DDB1- and CUL4-associated factor 16 isoform X3\tK23626 DCAF16; DDB1- and CUL4-associated factor 16"
					},
					{
						"name":"100063621 DCAF17; DDB1- and CUL4-associated factor 17 isoform X1\tK23331 DCAF17; DDB1- and CUL4-associated factor 17"
					},
					{
						"name":"100059579 BRWD1; bromodomain and WD repeat-containing protein 1 isoform X1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"100071730 BRWD3; bromodomain and WD repeat-containing protein 3 isoform X1\tK11798 BRWD1_3; bromodomain and WD repeat domain containing protein 1\/3"
					},
					{
						"name":"100055826 WDR26; WD repeat-containing protein 26 isoform X1\tK22382 WDR26; WD repeat-containing protein 26"
					},
					{
						"name":"100053352 WDR70; WD repeat-containing protein 70\tK24752 WDR70; WD repeat-containing protein 70"
					},
					{
						"name":"100070718 WDR76; WD repeat-containing protein 76 isoform X1\tK24755 WDR76; WD repeat-containing protein 76"
					}
					]
				}
				]
			},
			{
				"name":"Cul5 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"106781847 RNF7; RING-box protein 2 isoform X1\tK10611 RBX2; RING-box protein 2"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100061726 CUL5; cullin-5\tK10612 CUL5; cullin 5"
					}
					]
				},
				{
					"name":"Adoptor protein",
					"children":[
					{
						"name":"100060902 ELOC; elongin-C\tK03872 ELOC; elongin-C"
					},
					{
						"name":"106781563 ELOB; elongin-B isoform X1\tK03873 ELOB; elongin-B"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100061510 CISH; cytokine-inducible SH2-containing protein isoform X2\tK04701 CISH; cytokine inducible SH2-containing protein"
					},
					{
						"name":"102148488 SOCS1; suppressor of cytokine signaling 1\tK04694 SOCS1; suppressor of cytokine signaling 1"
					},
					{
						"name":"100051952 SOCS2; suppressor of cytokine signaling 2\tK04695 SOCS2; suppressor of cytokine signaling 2"
					},
					{
						"name":"100050730 SOCS3; suppressor of cytokine signaling 3\tK04696 SOCS3; suppressor of cytokine signaling 3"
					},
					{
						"name":"100050301 SOCS4; suppressor of cytokine signaling 4\tK04697 SOCS4; suppressor of cytokine signaling 4"
					},
					{
						"name":"100053252 SOCS5; suppressor of cytokine signaling 5\tK04698 SOCS5; suppressor of cytokine signaling 5"
					},
					{
						"name":"100052089 SOCS6; suppressor of cytokine signaling 6\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"100069069 SOCS7; suppressor of cytokine signaling 7 isoform X1\tK04699 SOCS6_7; suppressor of cytokine signaling 6\/7"
					},
					{
						"name":"100059795 ASB1; LOW QUALITY PROTEIN: ankyrin repeat and SOCS box protein 1\tK10323 ASB1; ankyrin repeat and SOCS box protein 1"
					},
					{
						"name":"100064381 ASB2; ankyrin repeat and SOCS box protein 2\tK10324 ASB2; ankyrin repeat and SOCS box protein 2"
					},
					{
						"name":"100052747 ASB3; ankyrin repeat and SOCS box protein 3\tK10325 ASB3; ankyrin repeat and SOCS box protein 3"
					},
					{
						"name":"100052021 ASB4; ankyrin repeat and SOCS box protein 4 isoform X1\tK10326 ASB4; ankyrin repeat and SOCS box protein 4"
					},
					{
						"name":"100061344 ASB5; ankyrin repeat and SOCS box protein 5 isoform X2\tK10327 ASB5; ankyrin repeat and SOCS box protein 5"
					},
					{
						"name":"100069992 ASB6; ankyrin repeat and SOCS box protein 6 isoform X1\tK10328 ASB6; ankyrin repeat and SOCS box protein 6"
					},
					{
						"name":"100050201 ASB7; ankyrin repeat and SOCS box protein 7\tK10329 ASB7; ankyrin repeat and SOCS box protein 7"
					},
					{
						"name":"100050927 ASB8; ankyrin repeat and SOCS box protein 8 isoform X1\tK10330 ASB8; ankyrin repeat and SOCS box protein 8"
					},
					{
						"name":"100055785 ASB9; ankyrin repeat and SOCS box protein 9 isoform X1\tK10331 ASB9; ankyrin repeat and SOCS box protein 9"
					},
					{
						"name":"100064203 ASB10; ankyrin repeat and SOCS box protein 10 isoform X1\tK10332 ASB10; ankyrin repeat and SOCS box protein 10"
					},
					{
						"name":"100050799 ASB11; ankyrin repeat and SOCS box protein 11 isoform X1\tK10333 ASB11; ankyrin repeat and SOCS box protein 11"
					},
					{
						"name":"100054675 MTMR8; ankyrin repeat and SOCS box protein 12 isoform X8\tK10334 ASB12; ankyrin repeat and SOCS box protein 12"
					},
					{
						"name":"100070388 ASB13; ankyrin repeat and SOCS box protein 13 isoform X1\tK10335 ASB13; ankyrin repeat and SOCS box protein 13"
					},
					{
						"name":"100058612 ASB14; ankyrin repeat and SOCS box protein 14 isoform X1\tK10336 ASB14; ankyrin repeat and SOCS box protein 14"
					},
					{
						"name":"102149796 ASB15; ankyrin repeat and SOCS box protein 15 isoform X1\tK10337 ASB15; ankyrin repeat and SOCS box protein 15"
					},
					{
						"name":"100051179 ASB16; ankyrin repeat and SOCS box protein 16\tK10338 ASB16; ankyrin repeat and SOCS box protein 16"
					},
					{
						"name":"100067240 ASB17; ankyrin repeat and SOCS box protein 17\tK10339 ASB17; ankyrin repeat and SOCS box protein 17"
					},
					{
						"name":"100630909 ASB18; ankyrin repeat and SOCS box protein 18\tK10340 ASB18; ankyrin repeat and SOCS box protein 18"
					},
					{
						"name":"100058727 WSB1; WD repeat and SOCS box-containing protein 1 isoform X1\tK10341 WSB1; WD repeat and SOCS box-containing protein 1"
					},
					{
						"name":"100054898 WSB2; WD repeat and SOCS box-containing protein 2 isoform X1\tK10342 WSB2; WD repeat and SOCS box-containing protein 2"
					},
					{
						"name":"100051547 SPSB4; SPRY domain-containing SOCS box protein 4\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"100051697 SPSB1; SPRY domain-containing SOCS box protein 1\tK10343 SPSB1_4; SPRY domain-containing SOCS box protein 1\/4"
					},
					{
						"name":"111773910 SPSB2; SPRY domain-containing SOCS box protein 2 isoform X1\tK10344 SPSB2; SPRY domain-containing SOCS box protein 2"
					},
					{
						"name":"100067860 SPSB3; SPRY domain-containing SOCS box protein 3\tK10345 SPSB3; SPRY domain-containing SOCS box protein 3"
					},
					{
						"name":"100056579 RAB40B; ras-related protein Rab-40B\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"100066853 RAB40C; ras-related protein Rab-40C\tK07928 RAB40; Ras-related protein Rab-40"
					},
					{
						"name":"100051941 LRRC41; leucine-rich repeat-containing protein 41 isoform X1\tK10347 LRRC41; leucine-rich repeat-containing protein 41"
					},
					{
						"name":"100052133 RSPRY1; RING finger and SPRY domain-containing protein 1\tK23332 RSPRY1; RING finger and SPRY domain-containing protein 1"
					},
					{
						"name":"106782552 ANKRD9; LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 9\tK25208 ANKRD9; ankyrin repeat domain-containing protein 9"
					},
					{
						"name":"100065812 KLHDC1; kelch domain-containing protein 1 isoform X1\tK25810 KLHDC1; kelch domain-containing protein 1"
					}
					]
				}
				]
			},
			{
				"name":"Cul7 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100067262 CUL7; cullin-7\tK10613 CUL7; cullin 7"
					}
					]
				},
				{
					"name":"Adaptor protein",
					"children":[
					{
						"name":"100062946 SKP1; S-phase kinase-associated protein 1\tK03094 SKP1; S-phase kinase-associated protein 1"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100055213 FBXW8; F-box\/WD repeat-containing protein 8 isoform X1\tK10264 FBXW8; F-box and WD-40 domain protein 8"
					}
					]
				}
				]
			},
			{
				"name":"Cul8 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin"
				},
				{
					"name":"Adaptor protein"
				},
				{
					"name":"Target recognizing subunit"
				}
				]
			},
			{
				"name":"Cul9 complex",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055581 RBX1; E3 ubiquitin-protein ligase RBX1 isoform X1\tK03868 RBX1; E3 ubiquitin-protein ligase RBX1 [EC:2.3.2.32]"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100055106 CUL9; cullin-9 isoform X1\tK11970 CUL9; cullin 9"
					}
					]
				}
				]
			},
			{
				"name":"APC\/C",
				"children":[
				{
					"name":"Ring finger protein",
					"children":[
					{
						"name":"100055053 ANAPC11; anaphase-promoting complex subunit 11\tK03358 APC11; anaphase-promoting complex subunit 11"
					}
					]
				},
				{
					"name":"Cullin",
					"children":[
					{
						"name":"100059767 ANAPC2; anaphase-promoting complex subunit 2\tK03349 APC2; anaphase-promoting complex subunit 2"
					}
					]
				},
				{
					"name":"Target recognizing subunit",
					"children":[
					{
						"name":"100053348 CDC20; cell division cycle protein 20 homolog\tK03363 CDC20; cell division cycle 20, cofactor of APC complex"
					},
					{
						"name":"100061287 FZR1; fizzy-related protein homolog isoform X1\tK03364 CDH1; cell division cycle 20-like protein 1, cofactor of APC complex"
					}
					]
				},
				{
					"name":"Other subunits",
					"children":[
					{
						"name":"100051869 ANAPC1; anaphase-promoting complex subunit 1 isoform X1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"111767487 anaphase-promoting complex subunit 1 isoform X1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"111768045 anaphase-promoting complex subunit 1 isoform X1\tK03348 APC1; anaphase-promoting complex subunit 1"
					},
					{
						"name":"100054552 CDC27; cell division cycle protein 27 homolog isoform X6\tK03350 APC3; anaphase-promoting complex subunit 3"
					},
					{
						"name":"100067388 ANAPC4; anaphase-promoting complex subunit 4 isoform X1\tK03351 APC4; anaphase-promoting complex subunit 4"
					},
					{
						"name":"100058548 ANAPC5; anaphase-promoting complex subunit 5\tK03352 APC5; anaphase-promoting complex subunit 5"
					},
					{
						"name":"100069285 CDC16; cell division cycle protein 16 homolog isoform X1\tK03353 APC6; anaphase-promoting complex subunit 6"
					},
					{
						"name":"100058376 ANAPC7; anaphase-promoting complex subunit 7 isoform X1\tK03354 APC7; anaphase-promoting complex subunit 7"
					},
					{
						"name":"100072599 CDC23; cell division cycle protein 23 homolog\tK03355 APC8; anaphase-promoting complex subunit 8"
					},
					{
						"name":"100062837 ANAPC10; anaphase-promoting complex subunit 10 isoform X1\tK03357 APC10; anaphase-promoting complex subunit 10"
					},
					{
						"name":"100053266 CDC26; anaphase-promoting complex subunit CDC26 isoform X1\tK03359 APC12; anaphase-promoting complex subunit 12"
					},
					{
						"name":"100053101 ANAPC13; anaphase-promoting complex subunit 13\tK12456 APC13; anaphase-promoting complex subunit 13"
					},
					{
						"name":"100066106 ANAPC15; anaphase-promoting complex subunit 15 isoform X2\tK25228 APC15; anaphase-promoting complex subunit 15"
					},
					{
						"name":"100072806 ANAPC16; anaphase-promoting complex subunit 16 isoform X2\tK25229 APC16; anaphase-promoting complex subunit 16"
					}
					]
				}
				]
			},
			{
				"name":"BRCC complex",
				"children":[
				{
					"name":"100051990 BRCA1; breast cancer type 1 susceptibility protein isoform X4\tK10605 BRCA1; breast cancer type 1 susceptibility protein [EC:2.3.2.27]"
				},
				{
					"name":"100064578 BRCA2; breast cancer type 2 susceptibility protein isoform X1\tK08775 BRCA2; breast cancer 2 susceptibility protein"
				},
				{
					"name":"100062237 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100053962 BARD1; BRCA1-associated RING domain protein 1\tK10683 BARD1; BRCA1-associated RING domain protein 1"
				},
				{
					"name":"100054872 BABAM2; BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				},
				{
					"name":"100071340 RAD51; DNA repair protein RAD51 homolog 1\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			},
			{
				"name":"KPC complex",
				"children":[
				{
					"name":"100053010 RNF123; E3 ubiquitin-protein ligase RNF123 isoform X5\tK12169 KPC1; Kip1 ubiquitination-promoting complex protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100068463 UBAC1; ubiquitin-associated domain-containing protein 1\tK12174 KPC2; Kip1 ubiquitination-promoting complex protein 2"
				}
				]
			},
			{
				"name":"LUBAC complex",
				"children":[
				{
					"name":"100065232 SHARPIN; sharpin isoform X1\tK20894 SHARPIN; shank-associated RH domain-interacting protein"
				},
				{
					"name":"100071666 sharpin\tK20894 SHARPIN; shank-associated RH domain-interacting protein"
				},
				{
					"name":"100067987 RBCK1; ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform X1\tK10630 RBCK1; RanBP-type and C3HC4-type zinc finger-containing protein 1 [EC:2.3.2.31]"
				}
				]
			},
			{
				"name":"CTLH complex",
				"children":[
				{
					"name":"100058137 RMND5B; protein RMD5 homolog B isoform X5\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"100066793 RMND5A; protein RMD5 homolog A\tK23333 RMND5; E3 ubiquitin-protein transferase RMND5 [EC:2.3.2.27]"
				},
				{
					"name":"100065036 RANBP9; ran-binding protein 9\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"100066243 RANBP10; ran-binding protein 10\tK23334 RANBP9_10; Ran-binding protein 9\/10"
				},
				{
					"name":"100066776 ARMC8; armadillo repeat-containing protein 8 isoform X3\tK23336 ARMC8; armadillo repeat-containing protein 8"
				},
				{
					"name":"100068568 MKLN1; muskelin isoform X1\tK23337 MKLN1; muskelin"
				},
				{
					"name":"100052280 MAEA; macrophage erythroblast attacher isoform X3\tK18624 MAEA; macrophage erythroblast attacher"
				},
				{
					"name":"100052039 GID4; LOW QUALITY PROTEIN: glucose-induced degradation protein 4 homolog\tK23335 GID4; glucose-induced degradation protein 4"
				},
				{
					"name":"100051346 GID8; glucose-induced degradation protein 8 homolog\tK23338 GID8; glucose-induced degradation protein 8"
				},
				{
					"name":"100054741 YPEL5; protein yippee-like 5\tK23339 YPEL5; protein yippee-like 5"
				},
				{
					"name":"100055826 WDR26; WD repeat-containing protein 26 isoform X1\tK22382 WDR26; WD repeat-containing protein 26"
				}
				]
			},
			{
				"name":"ERAD complex",
				"children":[
				{
					"name":"100061759 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100064100 TMUB1; transmembrane and ubiquitin-like domain-containing protein 1 isoform X2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"100064778 TMUB2; transmembrane and ubiquitin-like domain-containing protein 2 isoform X2\tK23340 TMUB; transmembrane and ubiquitin-like domain-containing protein"
				},
				{
					"name":"100057973 ERLIN2; erlin-2\tK23341 ERLIN; erlin"
				},
				{
					"name":"100060589 ERLIN1; erlin-1 isoform X1\tK23341 ERLIN; erlin"
				}
				]
			},
			{
				"name":"LMBR1L-GP78-UBAC2 complex",
				"children":[
				{
					"name":"100051779 LMBR1L; protein LMBR1L isoform X5\tK25215 LMBR1L; protein LMBR1L"
				},
				{
					"name":"100061759 AMFR; E3 ubiquitin-protein ligase AMFR\tK10636 AMFR; E3 ubiquitin-protein ligase AMFR [EC:2.3.2.36]"
				},
				{
					"name":"100061123 UBAC2; ubiquitin-associated domain-containing protein 2 isoform X1\tK25216 UBAC2; ubiquitin-associated domain-containing protein 2"
				}
				]
			},
			{
				"name":"STUB1-CHIC2  complex",
				"children":[
				{
					"name":"100066999 STUB1; E3 ubiquitin-protein ligase CHIP\tK09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]"
				},
				{
					"name":"100054052 CHIC2; cysteine-rich hydrophobic domain-containing protein 2\tK28185 CHIC2; cysteine-rich hydrophobic domain-containing protein 2"
				}
				]
			},
			{
				"name":"SLX5-SLX8 complex"
			},
			{
				"name":"Multi subunit type E3 associated proteins",
				"children":[
				{
					"name":"100058333 CAND1; cullin-associated NEDD8-dissociated protein 1 isoform X1\tK17263 CAND1; cullin-associated NEDD8-dissociated protein 1"
				},
				{
					"name":"100050966 CAND2; cullin-associated NEDD8-dissociated protein 2\tK24172 CAND2; cullin-associated NEDD8-dissociated protein 2"
				},
				{
					"name":"100051870 COMMD1; COMM domain-containing protein 1 isoform X1\tK22557 COMMD1; COMM domain containing 1"
				},
				{
					"name":"100050583 COMMD2; COMM domain-containing protein 2 isoform X1\tK22558 COMMD2; COMM domain containing 2"
				},
				{
					"name":"100055759 COMMD3; COMM domain-containing protein 3 isoform X1\tK22559 COMMD3; COMM domain containing 3"
				},
				{
					"name":"100061677 COMMD4; COMM domain-containing protein 4\tK22560 COMMD4; COMM domain containing 4"
				},
				{
					"name":"100064332 COMMD5; COMM domain-containing protein 5\tK22561 COMMD5; COMM domain containing 5"
				},
				{
					"name":"100049821 COMMD6; COMM domain-containing protein 6 isoform X2\tK22562 COMMD6; COMM domain containing 6"
				},
				{
					"name":"100068709 COMMD7; COMM domain-containing protein 7\tK22563 COMMD7; COMM domain containing 7"
				},
				{
					"name":"100146175 COMMD8; COMM domain-containing protein 8\tK22564 COMMD8; COMM domain containing 8"
				},
				{
					"name":"100052172 COMMD9; COMM domain-containing protein 9 isoform X2\tK22565 COMMD9; COMM domain containing 9"
				},
				{
					"name":"100073153 COMMD10; COMM domain-containing protein 10 isoform X1\tK22566 COMMD10; COMM domain containing 10"
				},
				{
					"name":"100052164 CCDC22; coiled-coil domain-containing protein 22\tK23343 CCDC22; coiled-coil domain-containing protein 22"
				},
				{
					"name":"100066678 DDRGK1; DDRGK domain-containing protein 1\tK23344 DDRGK1; DDRGK domain-containing protein 1"
				},
				{
					"name":"100051435 GLMN; glomulin isoform X1\tK23345 GLMN; glomulin"
				},
				{
					"name":"100052212 IVNS1ABP; influenza virus NS1A-binding protein isoform X1\tK15046 IVNS1ABP; influenza virus NS1A-binding protein"
				},
				{
					"name":"100069887 UBXN7; UBX domain-containing protein 7\tK24350 UBXN7; UBX domain-containing protein 7"
				},
				{
					"name":"100050378 PACRG; parkin coregulated gene protein\tK26163 PACRG; parkin coregulated gene protein"
				},
				{
					"name":"100056822 UBAP2L; ubiquitin-associated protein 2-like isoform X1\tK26545 UBAP2; ubiquitin-associated protein 2"
				},
				{
					"name":"100057140 UEVLD; ubiquitin-conjugating enzyme E2 variant 3 isoform X2\tK28518 UEVLD; ubiquitin-conjugating enzyme E2 variant 3"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Deubiquitinating enzyme (DUB)",
		"children":[
		{
			"name":"Ubiquitin-specific proteases (UBPs)",
			"children":[
			{
				"name":"UCH",
				"children":[
				{
					"name":"100033838 UCHL1; ubiquitin carboxyl-terminal hydrolase isozyme L1\tK05611 UCHL1; ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12]"
				},
				{
					"name":"100051934 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 isoform X1\tK08588 BAP1; ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12]"
				},
				{
					"name":"100050355 ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"100052000 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
				},
				{
					"name":"100059547 UCHL5; ubiquitin carboxyl-terminal hydrolase isozyme L5 isoform X1\tK05610 UCHL5; ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"UBP\/USP",
				"children":[
				{
					"name":"100050308 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD isoform X1\tK08601 CYLD; ubiquitin carboxyl-terminal hydrolase CYLD [EC:3.4.19.12]"
				},
				{
					"name":"100070397 USP1; ubiquitin carboxyl-terminal hydrolase 1 isoform X1\tK11832 USP1; ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12]"
				},
				{
					"name":"100067159 USP3; ubiquitin carboxyl-terminal hydrolase 3\tK11986 USP3; ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12]"
				},
				{
					"name":"100051171 USP11; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 11\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"100053443 USP4; ubiquitin carboxyl-terminal hydrolase 4 isoform X1\tK11835 USP4_11; ubiquitin carboxyl-terminal hydrolase 4\/11 [EC:3.4.19.12]"
				},
				{
					"name":"100060068 USP5; ubiquitin carboxyl-terminal hydrolase 5 isoform X1\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"100065844 USP13; ubiquitin carboxyl-terminal hydrolase 13\tK11836 USP5_13; ubiquitin carboxyl-terminal hydrolase 5\/13 [EC:3.4.19.12]"
				},
				{
					"name":"100071369 USP32; ubiquitin carboxyl-terminal hydrolase 32\tK11837 USP6_32; ubiquitin carboxyl-terminal hydrolase 6\/32 [EC:3.4.19.12]"
				},
				{
					"name":"100057484 USP7; ubiquitin carboxyl-terminal hydrolase 7 isoform X1\tK11838 USP7; ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12]"
				},
				{
					"name":"100055443 USP8; ubiquitin carboxyl-terminal hydrolase 8 isoform X1\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"100050489 USP9X; probable ubiquitin carboxyl-terminal hydrolase FAF-X\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"100060124 USP24; ubiquitin carboxyl-terminal hydrolase 24 isoform X1\tK11840 USP9_24; ubiquitin carboxyl-terminal hydrolase 9\/24 [EC:3.4.19.12]"
				},
				{
					"name":"100070208 USP10; ubiquitin carboxyl-terminal hydrolase 10 isoform X1\tK11841 USP10; ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12]"
				},
				{
					"name":"100060432 USP46; ubiquitin carboxyl-terminal hydrolase 46\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"100060694 USP12; ubiquitin carboxyl-terminal hydrolase 12 isoform X1\tK11842 USP12_46; ubiquitin carboxyl-terminal hydrolase 12\/46 [EC:3.4.19.12]"
				},
				{
					"name":"100060643 USP14; ubiquitin carboxyl-terminal hydrolase 14 isoform X1\tK11843 USP14; ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12]"
				},
				{
					"name":"100055857 USP15; ubiquitin carboxyl-terminal hydrolase 15 isoform X1\tK21343 USP15; ubiquitin carboxyl-terminal hydrolase 15 [EC:3.4.19.12]"
				},
				{
					"name":"100053798 USP16; ubiquitin carboxyl-terminal hydrolase 16\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"100071616 USP45; ubiquitin carboxyl-terminal hydrolase 45 isoform X1\tK11844 USP16_45; ubiquitin carboxyl-terminal hydrolase 16\/45 [EC:3.4.19.12]"
				},
				{
					"name":"100063044 ubiquitin carboxyl-terminal hydrolase 17-like protein 6\tK11845 USP17; ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12]"
				},
				{
					"name":"100054488 USP18; ubl carboxyl-terminal hydrolase 18\tK11846 USP18_41; ubiquitin carboxyl-terminal hydrolase 18\/41 [EC:3.4.19.12]"
				},
				{
					"name":"100053587 USP19; ubiquitin carboxyl-terminal hydrolase 19 isoform X7\tK11847 USP19; ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12]"
				},
				{
					"name":"100053171 USP33; ubiquitin carboxyl-terminal hydrolase 33 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"100066778 USP20; ubiquitin carboxyl-terminal hydrolase 20 isoform X1\tK11848 USP20_33; ubiquitin carboxyl-terminal hydrolase 20\/33 [EC:3.4.19.12]"
				},
				{
					"name":"100066197 USP21; ubiquitin carboxyl-terminal hydrolase 21\tK21634 USP21; ubiquitin carboxyl-terminal hydrolase 21 [EC:3.4.19.12]"
				},
				{
					"name":"100050479 USP51; ubiquitin carboxyl-terminal hydrolase 51\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"100053238 USP22; ubiquitin carboxyl-terminal hydrolase 22\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"100063066 USP27X; ubiquitin carboxyl-terminal hydrolase 27\tK11366 USP22_27_51; ubiquitin carboxyl-terminal hydrolase 22\/27\/51 [EC:3.4.19.12]"
				},
				{
					"name":"100147361 USP25; ubiquitin carboxyl-terminal hydrolase 25 isoform X1\tK11849 USP25; ubiquitin carboxyl-terminal hydrolase 25 [EC:3.4.19.12]"
				},
				{
					"name":"100055721 USP37; ubiquitin carboxyl-terminal hydrolase 37 isoform X1\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"100057231 USP26; ubiquitin carboxyl-terminal hydrolase 26\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"100059339 USP29; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 29\tK11850 USP26_29_37; ubiquitin carboxyl-terminal hydrolase 26\/29\/37 [EC:3.4.19.12]"
				},
				{
					"name":"100070736 USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform X1\tK21122 USP28; ubiquitin carboxyl-terminal hydrolase 28 [EC:3.4.19.12]"
				},
				{
					"name":"100066762 USP30; ubiquitin carboxyl-terminal hydrolase 30 isoform X1\tK11851 USP30; ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12]"
				},
				{
					"name":"100068897 USP31; ubiquitin carboxyl-terminal hydrolase 31 isoform X1\tK11852 USP31; ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12]"
				},
				{
					"name":"100064939 USP34; ubiquitin carboxyl-terminal hydrolase 34 isoform X1\tK11853 USP34; ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12]"
				},
				{
					"name":"100062906 USP35; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 35\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"100062951 USP38; ubiquitin carboxyl-terminal hydrolase 38 isoform X1\tK11854 USP35_38; ubiquitin carboxyl-terminal hydrolase 35\/38 [EC:3.4.19.12]"
				},
				{
					"name":"100057557 USP36; ubiquitin carboxyl-terminal hydrolase 36 isoform X2\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100062198 USP42; ubiquitin carboxyl-terminal hydrolase 42 isoform X1\tK11855 USP36_42; ubiquitin carboxyl-terminal hydrolase 36\/42 [EC:3.4.19.12]"
				},
				{
					"name":"100065074 USP40; ubiquitin carboxyl-terminal hydrolase 40 isoform X1\tK11869 USP40; ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12]"
				},
				{
					"name":"100073074 USP43; ubiquitin carboxyl-terminal hydrolase 43 isoform X1\tK11856 USP43; ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12]"
				},
				{
					"name":"100065395 USP44; ubiquitin carboxyl-terminal hydrolase 44\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"100066518 USP49; LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 49\tK11834 USP44_49; ubiquitin carboxyl-terminal hydrolase 44\/49 [EC:3.4.19.12]"
				},
				{
					"name":"100071433 USP47; ubiquitin carboxyl-terminal hydrolase 47 isoform X1\tK11857 USP47; ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12]"
				},
				{
					"name":"100058232 USP48; ubiquitin carboxyl-terminal hydrolase 48 isoform X1\tK11858 USP48; ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12]"
				},
				{
					"name":"100069882 USP50; inactive ubiquitin carboxyl-terminal hydrolase 50 isoform X1\tK28833 USP50; ubiquitin carboxyl-terminal hydrolase 50 [EC:3.4.19.12]"
				},
				{
					"name":"100063948 USP54; inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1\tK27920 USP54; ubiquitin carboxyl-terminal hydrolase 54 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"OTU",
				"children":[
				{
					"name":"100054829 OTUB1; ubiquitin thioesterase OTUB1\tK09602 OTUB1; ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12]"
				},
				{
					"name":"100064732 OTUB2; ubiquitin thioesterase OTUB2 isoform X2\tK09603 OTUB2; ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12]"
				},
				{
					"name":"100071874 OTUD3; OTU domain-containing protein 3 isoform X1\tK13717 OTUD3; OTU domain-containing protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"100062519 OTUD5; OTU domain-containing protein 5 isoform X2\tK12655 OTUD5; OTU domain-containing protein 5 [EC:3.4.19.12]"
				},
				{
					"name":"100052944 OTUD6B; LOW QUALITY PROTEIN: OTU domain-containing protein 6B\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"100056237 LOW QUALITY PROTEIN: OTU domain-containing protein 6A\tK18342 OTUD6; OTU domain-containing protein 6 [EC:3.4.19.12]"
				},
				{
					"name":"100054396 OTUD7B; OTU domain-containing protein 7B isoform X3\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"100060048 OTUD7A; OTU domain-containing protein 7A isoform X1\tK11860 OTUD7A_B; OTU domain-containing protein 7 [EC:3.4.19.12]"
				},
				{
					"name":"100070204 OTULIN; ubiquitin thioesterase otulin\tK18343 OTULIN; ubiquitin thioesterase otulin [EC:3.4.19.12]"
				},
				{
					"name":"100073197 TNFAIP3; tumor necrosis factor alpha-induced protein 3 isoform X1\tK11859 TNFAIP3; tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12]"
				},
				{
					"name":"100052090 VCPIP1; deubiquitinating protein VCIP135\tK11861 VCPIP1; deubiquitinating protein VCIP135 [EC:3.4.19.12]"
				},
				{
					"name":"100050133 ZRANB1; ubiquitin thioesterase ZRANB1 isoform X1\tK11862 ZRANB1; ubiquitin thioesterase ZRANB1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MJD",
				"children":[
				{
					"name":"100053162 ATXN3; ataxin-3\tK11863 ATXN3; ataxin-3 [EC:3.4.22.-]"
				},
				{
					"name":"100055255 JOSD1; josephin-1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				},
				{
					"name":"111775247 JOSD2; josephin-2 isoform X1\tK15235 JOSD; josephin [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"MINDY",
				"children":[
				{
					"name":"100055075 MINDY1; ubiquitin carboxyl-terminal hydrolase MINDY-1\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"100068294 MINDY2; ubiquitin carboxyl-terminal hydrolase MINDY-2 isoform X1\tK01309 MINDY1_2; ubiquitin carboxyl-terminal hydrolase MINDY-1\/2 [EC:3.4.19.12]"
				},
				{
					"name":"100055117 MINDY4; probable ubiquitin carboxyl-terminal hydrolase MINDY-4 isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"100056170 MINDY3; ubiquitin carboxyl-terminal hydrolase MINDY-3 isoform X1\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				},
				{
					"name":"111768276 MINDY4B; inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B\tK22647 MINDY3_4; ubiquitin carboxyl-terminal hydrolase MINDY-3\/4 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"JAMM",
				"children":[
				{
					"name":"100062237 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100146753 MYSM1; histone H2A deubiquitinase MYSM1 isoform X1\tK11865 MYSM1; histone H2A deubiquitinase [EC:3.4.19.-]"
				},
				{
					"name":"100146444 MPND; MPN domain-containing protein isoform X1\tK24173 MPND; MPN domain-containing protein"
				},
				{
					"name":"100051409 PSMD14; 26S proteasome non-ATPase regulatory subunit 14 isoform X2\tK03030 PSMD14; 26S proteasome regulatory subunit N11"
				},
				{
					"name":"100049814 STAMBP; STAM-binding protein isoform X3\tK11866 STAMBP; STAM-binding protein [EC:3.4.19.12]"
				},
				{
					"name":"100062209 STAMBPL1; AMSH-like protease isoform X1\tK11867 STAMBPL1; AMSH-like protease [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"PPPDE",
				"children":[
				{
					"name":"100062283 DESI2; desumoylating isopeptidase 2 isoform X1\tK22763 DESI2; deubiquitinase DESI2 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"ZUFSP",
				"children":[
				{
					"name":"100067070 ZUFSP; zinc finger with UFM1-specific peptidase domain protein isoform X2\tK24134 ZUP1; zinc finger-containing ubiquitin peptidase 1 [EC:3.4.19.12]"
				}
				]
			},
			{
				"name":"BRISC complex",
				"children":[
				{
					"name":"100057158 ABRAXAS2; BRISC complex subunit Abraxas 2\tK20799 FAM175B; BRISC complex subunit Abro1"
				},
				{
					"name":"100069531 BABAM1; BRISC and BRCA1-A complex member 1 isoform X2\tK20776 BABAM; BRISC and BRCA1-A complex member 1"
				},
				{
					"name":"100062237 BRCC3; lys-63-specific deubiquitinase BRCC36 isoform X1\tK11864 BRCC3; BRCA1\/BRCA2-containing complex subunit 3 [EC:3.4.19.-]"
				},
				{
					"name":"100054872 BABAM2; BRISC and BRCA1-A complex member 2\tK12173 BRE; BRCA1-A complex subunit BRE"
				}
				]
			}
			]
		},
		{
			"name":"UBL-specific proteases (ULPs)",
			"children":[
			{
				"name":"100056855 SENP1; sentrin-specific protease 1 isoform X2\tK08592 SENP1; sentrin-specific protease 1 [EC:3.4.22.68]"
			},
			{
				"name":"100059276 SENP2; sentrin-specific protease 2 isoform X1\tK03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]"
			},
			{
				"name":"102148314 SENP3; sentrin-specific protease 3 isoform X1\tK08593 SENP3; sentrin-specific protease 3 [EC:3.4.22.68]"
			},
			{
				"name":"100069684 SENP5; sentrin-specific protease 5 isoform X1\tK08594 SENP5; sentrin-specific protease 5 [EC:3.4.22.68]"
			},
			{
				"name":"100068828 SENP6; sentrin-specific protease 6 isoform X1\tK08595 SENP6; sentrin-specific protease 6 [EC:3.4.22.68]"
			},
			{
				"name":"100072208 SENP7; sentrin-specific protease 7 isoform X2\tK08596 SENP7; sentrin-specific protease 7 [EC:3.4.22.68]"
			},
			{
				"name":"100052291 SENP8; sentrin-specific protease 8\tK08597 SENP8; sentrin-specific protease 8 [EC:3.4.22.68]"
			},
			{
				"name":"100050355 ubiquitin carboxyl-terminal hydrolase isozyme L3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"100052000 UCHL3; ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X3\tK05609 UCHL3; ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12]"
			},
			{
				"name":"100070677 DESI1; desumoylating isopeptidase 1\tK22762 DESI1; desumoylating isopeptidase 1 [EC:3.4.-.-]"
			},
			{
				"name":"100062086 USPL1; SUMO-specific isopeptidase USPL1 isoform X1\tK23008 USPL1; SUMO-specific isopeptidase USPL1 [EC:3.4.22.-]"
			},
			{
				"name":"COP9 signalosome (CSN) complex",
				"children":[
				{
					"name":"100056238 GPS1; COP9 signalosome complex subunit 1 isoform X1\tK12175 GPS1; COP9 signalosome complex subunit 1"
				},
				{
					"name":"100055653 COPS2; COP9 signalosome complex subunit 2 isoform X2\tK12176 COPS2; COP9 signalosome complex subunit 2"
				},
				{
					"name":"100051092 COPS3; COP9 signalosome complex subunit 3 isoform X1\tK12177 COPS3; COP9 signalosome complex subunit 3"
				},
				{
					"name":"100052196 COPS4; COP9 signalosome complex subunit 4 isoform X1\tK12178 COPS4; COP9 signalosome complex subunit 4"
				},
				{
					"name":"100051846 COPS5; COP9 signalosome complex subunit 5\tK09613 COPS5; COP9 signalosome complex subunit 5 [EC:3.4.-.-]"
				},
				{
					"name":"100068657 COPS6; COP9 signalosome complex subunit 6\tK12179 COPS6; COP9 signalosome complex subunit 6"
				},
				{
					"name":"100059941 COPS7A; COP9 signalosome complex subunit 7a\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"100064349 COPS7B; COP9 signalosome complex subunit 7b isoform X1\tK12180 COPS7; COP9 signalosome complex subunit 7"
				},
				{
					"name":"100057535 COPS8; COP9 signalosome complex subunit 8\tK12181 COPS8; COP9 signalosome complex subunit 8"
				},
				{
					"name":"100067241 COPS9; COP9 signalosome complex subunit 9\tK28062 COPS9; COP9 signalosome complex subunit 9"
				}
				]
			}
			]
		}
		]
	}
	]
}