{
	"name":"ko01001",
	"children":[
	{
		"name":"Serine\/threonine kinases: AGC group",
		"children":[
		{
			"name":"PKA family",
			"children":[
			{
				"name":"K04345  PKA; protein kinase A [EC:2.7.11.11]"
			},
			{
				"name":"K19584  PRKX; protein kinase X [EC:2.7.11.11]"
			}
			]
		},
		{
			"name":"PKG family",
			"children":[
			{
				"name":"K07376  PRKG1; cGMP-dependent protein kinase 1 [EC:2.7.11.12]"
			},
			{
				"name":"K19477  PRKG2; cGMP-dependent protein kinase 2 [EC:2.7.11.12]"
			}
			]
		},
		{
			"name":"PKC family [OT]",
			"children":[
			{
				"name":"K02677  PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
			},
			{
				"name":"K19662  PRKCB; classical protein kinase C beta type [EC:2.7.11.13]"
			},
			{
				"name":"K19663  PRKCG; classical protein kinase C gamma type [EC:2.7.11.13]"
			},
			{
				"name":"K06068  PRKCD; novel protein kinase C delta type [EC:2.7.11.13]"
			},
			{
				"name":"K18050  PRKCE; novel protein kinase C epsilon type [EC:2.7.11.13]"
			},
			{
				"name":"K18051  PRKCH; novel protein kinase C eta type [EC:2.7.11.13]"
			},
			{
				"name":"K18052  PRKCQ; novel protein kinase C theta type [EC:2.7.11.13]"
			},
			{
				"name":"K18952  PRKCZ; atypical protein kinase C zeta type [EC:2.7.11.13]"
			},
			{
				"name":"K06069  PRKCI; atypical protein kinase C iota type [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PKN family",
			"children":[
			{
				"name":"K06071  PKN1; serine\/threonine-protein kinase N1 [EC:2.7.11.13]"
			},
			{
				"name":"K23691  PKN2; serine\/threonine-protein kinase N2 [EC:2.7.11.13]"
			},
			{
				"name":"K23692  PKN3; serine\/threonine-protein kinase N3 [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"AUR family [OT]",
			"children":[
			{
				"name":"K11481  AURKA; aurora kinase A [EC:2.7.11.1]"
			},
			{
				"name":"K11479  AURKB; aurora kinase B [EC:2.7.11.1]"
			},
			{
				"name":"K11480  AURKC; aurora kinase C [EC:2.7.11.1]"
			},
			{
				"name":"K08850  AURKX; aurora kinase, other [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PDK1 family",
			"children":[
			{
				"name":"K06276  PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"AKT\/PKB family",
			"children":[
			{
				"name":"K04456  AKT; RAC serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K19800  SCH9; serine\/threonine protein kinase SCH9 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"SGK family [OT]",
			"children":[
			{
				"name":"K13302  SGK1; serum\/glucocorticoid-regulated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K13303  SGK2; serum\/glucocorticoid-regulated kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K13304  SGK3; serum\/glucocorticoid-regulated kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RSK family [OT]",
			"children":[
			{
				"name":"K04373  RPS6KA; ribosomal protein S6 kinase alpha-1\/2\/3\/6 [EC:2.7.11.1]"
			},
			{
				"name":"K16510  RPS6KA4, MSK2; ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1]"
			},
			{
				"name":"K04445  RPS6KA5, MSK1; ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1]"
			},
			{
				"name":"K04688  RPS6KB; ribosomal protein S6 kinase beta [EC:2.7.11.1]"
			},
			{
				"name":"K20839  RSKL; ribosomal protein S6 kinase-like"
			},
			{
				"name":"K22008  PSK1; serine\/threonine-protein kinase Psk1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NDR family",
			"children":[
			{
				"name":"K08790  STK38, NDR; serine\/threonine kinase 38 [EC:2.7.11.1]"
			},
			{
				"name":"K08791  LATS1_2, Wts; serine\/threonine-protein kinase LATS1\/2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAST family [OT]",
			"children":[
			{
				"name":"K08789  MAST, IREH1; MAST-subfamily protein kinase [EC:2.7.11.37]"
			},
			{
				"name":"K16309  MASTL, GW; serine\/threonine-protein kinase greatwall [EC:2.7.11.36]"
			},
			{
				"name":"K12767  RIM15; serine\/threonine-protein kinase RIM15 [EC:2.7.11.36]"
			}
			]
		},
		{
			"name":"YANK family",
			"children":[
			{
				"name":"K08793  STK32, YANK; serine\/threonine kinase 32 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DMPK family [OT]",
			"children":[
			{
				"name":"K08788  DMPK; dystrophia myotonica-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K04514  ROCK1; Rho-associated protein kinase 1 [EC:2.7.11.39]"
			},
			{
				"name":"K17388  ROCK2; Rho-associated protein kinase 2 [EC:2.7.11.39]"
			},
			{
				"name":"K16307  CDC42BP; serine\/threonine-protein kinase MRCK [EC:2.7.11.1]"
			},
			{
				"name":"K16308  CIT; citron Rho-interacting kinase [EC:2.7.11.35]"
			}
			]
		},
		{
			"name":"GRK family [OT]",
			"children":[
			{
				"name":"K00909  GRK1_7; rhodopsin kinase [EC:2.7.11.14]"
			},
			{
				"name":"K00910  ADRBK, GRK; beta-adrenergic-receptor kinase [EC:2.7.11.15]"
			},
			{
				"name":"K08291  GRK4_5_6; G protein-coupled receptor kinase [EC:2.7.11.16]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K17529  SGK494; uncharacterized serine\/threonine-protein kinase SgK494 [EC:2.7.11.1]"
			},
			{
				"name":"K20714  OXI1; serine\/threonine-protein kinase OXI1 [EC:2.7.11.1]"
			},
			{
				"name":"K20715  PHOT; phototropin [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CAMK group",
		"children":[
		{
			"name":"CAMK1 family [OT]",
			"children":[
			{
				"name":"K08794  CAMK1; calcium\/calmodulin-dependent protein kinase I [EC:2.7.11.17]"
			},
			{
				"name":"K05869  CAMK4; calcium\/calmodulin-dependent protein kinase IV [EC:2.7.11.17]"
			},
			{
				"name":"K08795  PNCK; pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17]"
			},
			{
				"name":"K08812  CAMKV; CaM kinase-like vesicle-associated [EC:2.7.11.-]"
			}
			]
		},
		{
			"name":"CAMK2 family",
			"children":[
			{
				"name":"K04515  CAMK2; calcium\/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CAMKL family",
			"children":[
			{
				"name":"K08796  BRSK; BR serine\/threonine kinase [EC:2.7.11.1]"
			},
			{
				"name":"K02216  CHEK1; serine\/threonine-protein kinase CHEK1 [EC:2.7.11.1]"
			},
			{
				"name":"K08797  HUNK; hormonally upregulated Neu-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08798  MARK; MAP\/microtubule affinity-regulating kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08799  MELK; maternal embryonic leucine zipper kinase [EC:2.7.11.1]"
			},
			{
				"name":"K16310  NIM1; serine\/threonine-protein kinase NIM1 [EC:2.7.11.1]"
			},
			{
				"name":"K08800  NUAK; NUAK family, SNF1-like kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08801  PASK; PAS domain containing serine\/threonine kinase [EC:2.7.11.1]"
			},
			{
				"name":"K07198  PRKAA, AMPK; 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.31]"
			},
			{
				"name":"K19008  SIK1; serine\/threonine-protein kinase SIK1 [EC:2.7.11.1]"
			},
			{
				"name":"K16311  SIK2; serine\/threonine-protein kinase SIK2 [EC:2.7.11.1]"
			},
			{
				"name":"K19009  SIK3; serine\/threonine-protein kinase SIK3 [EC:2.7.11.1]"
			},
			{
				"name":"K08802  SNRK; SNF related kinase [EC:2.7.11.1]"
			},
			{
				"name":"K07298  STK11, LKB1; serine\/threonine-protein kinase 11 [EC:2.7.11.1]"
			},
			{
				"name":"K14498  SNRK2; serine\/threonine-protein kinase SRK2 [EC:2.7.11.1]"
			},
			{
				"name":"K12761  SNF1; carbon catabolite-derepressing protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K18639  KCC4; serine\/threonine-protein kinase KCC4 [EC:2.7.11.1]"
			},
			{
				"name":"K06668  GIN4; serine\/threonine-protein kinase GIN4 [EC:2.7.11.-]"
			},
			{
				"name":"K02515  HSL1; serine\/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]"
			},
			{
				"name":"K18680  CDR1; mitosis inducer protein kinase Cdr1 [EC:2.7.11.1]"
			},
			{
				"name":"K18679  CDR2; mitosis inducer protein kinase Cdr2 [EC:2.7.11.1]"
			},
			{
				"name":"K19852  KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
			},
			{
				"name":"K28035  NPR, HAL; NPR\/Hal family protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DAPK family",
			"children":[
			{
				"name":"K08803  DAPK; death-associated protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08804  STK17; serine\/threonine kinase 17 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"DCAMKL family",
			"children":[
			{
				"name":"K08805  DCLK1_2; doublecortin-like kinase 1\/2 [EC:2.7.11.1]"
			},
			{
				"name":"K17530  DCLK3; doublecortin-like kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MAPKAPK family [OT]",
			"children":[
			{
				"name":"K04443  MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K04444  MAPKAPK3; mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K04442  MAPKAPK5, PRAK; mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"K04372  MKNK, MNK; MAP kinase interacting serine\/threonine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MLCK family",
			"children":[
			{
				"name":"K00907  MYLK; myosin-light-chain kinase [EC:2.7.11.18]"
			},
			{
				"name":"K12567  TTN; titin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PHK family",
			"children":[
			{
				"name":"K00871  PHKG; phosphorylase kinase gamma subunit [EC:2.7.11.19]"
			}
			]
		},
		{
			"name":"PIM family [OT]",
			"children":[
			{
				"name":"K04702  PIM1; proto-oncogene serine\/threonine-protein kinase Pim-1 [EC:2.7.11.1]"
			},
			{
				"name":"K08806  PIM2; proto-oncogene serine\/threonine-protein kinase Pim-2 [EC:2.7.11.1]"
			},
			{
				"name":"K08807  PIM3; proto-oncogene serine\/threonine-protein kinase Pim-3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PKD family",
			"children":[
			{
				"name":"K06070  PKD; protein kinase D [EC:2.7.11.13]"
			}
			]
		},
		{
			"name":"PSK family",
			"children":[
			{
				"name":"K08808  PSKH; protein serine kinase H [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RAD53 family",
			"children":[
			{
				"name":"K06641  CHEK2; serine\/threonine-protein kinase CHEK2 [EC:2.7.11.1]"
			},
			{
				"name":"K12776  MEK1; meiosis-specific serine\/threonine-protein kinase MEK1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trio family [OT]",
			"children":[
			{
				"name":"K08809  SPEG; striated muscle-specific serine\/threonine protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08810  TRIO; triple functional domain protein [EC:2.7.11.1]"
			},
			{
				"name":"K15048  KALRN; kalirin [EC:2.7.11.1]"
			},
			{
				"name":"K17531  OBSCN, ARHGEF30; obscurin-RhoGEF [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TSSK family",
			"children":[
			{
				"name":"K08811  TSSK, STK22; testis-specific serine kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CDPK family",
			"children":[
			{
				"name":"K13412  CPK; calcium-dependent protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CASK family",
			"children":[
			{
				"name":"K06103  CASK; calcium\/calmodulin-dependent serine protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Trbl family",
			"children":[
			{
				"name":"K08814  TRIB1_2; tribbles homolog 1\/2"
			},
			{
				"name":"K19518  TRIB3; tribbles homolog 3"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K08813  STK33; serine\/threonine kinase 33 [EC:2.7.11.1]"
			},
			{
				"name":"K16312  STK40, SHIK; serine\/threonine-protein kinase 40 [EC:2.7.11.1]"
			},
			{
				"name":"K23785  RCK2, CLK1; serine\/threonine-protein kinase RCK2 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CK1 group",
		"children":[
		{
			"name":"CK1 family [OT]",
			"children":[
			{
				"name":"K08957  CSNK1A; casein kinase 1, alpha [EC:2.7.11.1]"
			},
			{
				"name":"K08958  CSNK1G; casein kinase 1, gamma [EC:2.7.11.1]"
			},
			{
				"name":"K08959  CSNK1D; casein kinase 1, delta [EC:2.7.11.1]"
			},
			{
				"name":"K08960  CSNK1E; casein kinase 1, epsilon [EC:2.7.11.1]"
			},
			{
				"name":"K02218  CSNK1, CKI; casein kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K19830  YCK3; casein kinase I homolog 3 [EC:2.7.11.1]"
			},
			{
				"name":"K14758  HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TTBK family",
			"children":[
			{
				"name":"K08815  TTBK; tau tubulin kinase [EC:2.7.11.26]"
			}
			]
		},
		{
			"name":"VRK family",
			"children":[
			{
				"name":"K08816  VRK; vaccinia related kinase [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: CMGC group",
		"children":[
		{
			"name":"CDK family",
			"children":[
			{
				"name":"K08817  CDK20, CCRK; cyclin-dependent kinase 20 [EC:2.7.11.22]"
			},
			{
				"name":"K08818  CDC2L; cell division cycle 2-like [EC:2.7.11.22]"
			},
			{
				"name":"K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
			},
			{
				"name":"K02088  CDK3; cyclin-dependent kinase 3 [EC:2.7.11.22]"
			},
			{
				"name":"K02089  CDK4; cyclin-dependent kinase 4 [EC:2.7.11.22]"
			},
			{
				"name":"K02090  CDK5; cyclin-dependent kinase 5 [EC:2.7.11.22]"
			},
			{
				"name":"K02091  CDK6; cyclin-dependent kinase 6 [EC:2.7.11.22]"
			},
			{
				"name":"K02202  CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K02208  CDK8_11; cyclin-dependent kinase 8\/11 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K02211  CDK9; cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K02449  CDK10; cyclin-dependent kinase 10 [EC:2.7.11.22]"
			},
			{
				"name":"K08819  CDK12_13; cyclin-dependent kinase 12\/13 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K08821  CDK14, PFTK1; cyclin-dependent kinase 14 [EC:2.7.11.22]"
			},
			{
				"name":"K15594  CDK15, PFTK2; cyclin-dependent kinase 15 [EC:2.7.11.22]"
			},
			{
				"name":"K08820  CDK16, PCTK1; cyclin-dependent kinase 16 [EC:2.7.11.22]"
			},
			{
				"name":"K15595  CDK17, PCTK2; cyclin-dependent kinase 17 [EC:2.7.11.22]"
			},
			{
				"name":"K15596  CDK18, PCTK3; cyclin-dependent kinase 18 [EC:2.7.11.22]"
			},
			{
				"name":"K07760  CDK; cyclin-dependent kinase [EC:2.7.11.22]"
			},
			{
				"name":"K15562  BUR1, SGV1; serine\/threonine-protein kinase BUR1 [EC:2.7.11.22 2.7.11.23]"
			},
			{
				"name":"K00916  CTK1; CTD kinase subunit alpha [EC:2.7.11.22 2.7.11.23]"
			}
			]
		},
		{
			"name":"MAPK family [OT]",
			"children":[
			{
				"name":"K04371  ERK, MAPK1_3; mitogen-activated protein kinase 1\/3 [EC:2.7.11.24]"
			},
			{
				"name":"K06855  MAPK4_6; mitogen-activated protein kinase 4\/6 [EC:2.7.11.24]"
			},
			{
				"name":"K04464  MAPK7; mitogen-activated protein kinase 7 [EC:2.7.11.24]"
			},
			{
				"name":"K19603  MAPK15; mitogen-activated protein kinase 15 [EC:2.7.11.24]"
			},
			{
				"name":"K04440  JNK; mitogen-activated protein kinase 8\/9\/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]"
			},
			{
				"name":"K04441  P38; p38 MAP kinase [EC:2.7.11.24]"
			},
			{
				"name":"K04468  NLK; nemo like kinase [EC:2.7.11.24]"
			},
			{
				"name":"K20535  MPK1_2; mitogen-activated protein kinase 1\/2 [EC:2.7.11.24]"
			},
			{
				"name":"K20536  MPK3; mitogen-activated protein kinase 3 [EC:2.7.11.24]"
			},
			{
				"name":"K20600  MPK4; mitogen-activated protein kinase 4 [EC:2.7.11.24]"
			},
			{
				"name":"K14512  MPK6; mitogen-activated protein kinase 6 [EC:2.7.11.24]"
			},
			{
				"name":"K20537  MPK7_14; mitogen-activated protein kinase 7\/14 [EC:2.7.11.24]"
			},
			{
				"name":"K20538  MPK8; mitogen-activated protein kinase 8 [EC:2.7.11.24]"
			},
			{
				"name":"K08293  SMK1; sporulation-specific mitogen-activated protein kinase SMK1 [EC:2.7.11.24]"
			}
			]
		},
		{
			"name":"GSK family [OT]",
			"children":[
			{
				"name":"K08822  GSK3A; glycogen synthase kinase 3 alpha [EC:2.7.11.26]"
			},
			{
				"name":"K03083  GSK3B; glycogen synthase kinase 3 beta [EC:2.7.11.26]"
			},
			{
				"name":"K27413  ASK1_3_5; shaggy-related protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K27414  ASK2_8; shaggy-related protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K14502  ASK6_7_9, BIN2; shaggy-related protein kinase (protein brassinosteroid insensitive 2) [EC:2.7.11.1]"
			},
			{
				"name":"K12766  MDS1, RIM11; serine\/threonine-protein kinase MDS1\/RIM11 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CLK family",
			"children":[
			{
				"name":"K23561  CLK1_4; dual specificity protein kinase CLK1\/4 [EC:2.7.12.1]"
			},
			{
				"name":"K08823  CLK2_3; dual specificity protein kinase CLK2\/3 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"CDKL family",
			"children":[
			{
				"name":"K08824  CDKL; cyclin-dependent kinase-like [EC:2.7.11.22]"
			}
			]
		},
		{
			"name":"DYRK family [OT]",
			"children":[
			{
				"name":"K08825  DYRK1; dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1]"
			},
			{
				"name":"K18669  DYRK2_3_4; dual specificity tyrosine-phosphorylation-regulated kinase 2\/3\/4 [EC:2.7.12.1]"
			},
			{
				"name":"K18670  YAK1; dual specificity protein kinase YAK1 [EC:2.7.12.1]"
			},
			{
				"name":"K08826  HIPK; homeodomain interacting protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08827  PRPF4B; serine\/threonine-protein kinase PRP4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RCK family [OT]",
			"children":[
			{
				"name":"K08828  ICK; intestinal cell (MAK-like) kinase [EC:2.7.11.22]"
			},
			{
				"name":"K08829  MAK; male germ cell-associated kinase [EC:2.7.11.22]"
			},
			{
				"name":"K08830  RAGE, MOK; renal tumor antigen [EC:2.7.11.22]"
			},
			{
				"name":"K12765  IME2; meiosis induction protein kinase IME2\/SME1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"SRPK family [OT]",
			"children":[
			{
				"name":"K15409  SRPK1; serine\/threonine-protein kinase SRPK1 [EC:2.7.11.1]"
			},
			{
				"name":"K08831  SRPK2; serine\/threonine-protein kinase SRPK2 [EC:2.7.11.1]"
			},
			{
				"name":"K08832  SRPK3, STK23; serine\/threonine-protein kinase SRPK3 [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: STE group",
		"children":[
		{
			"name":"STE7 family",
			"children":[
			{
				"name":"K04368  MAP2K1, MEK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]"
			},
			{
				"name":"K04369  MAP2K2, MEK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]"
			},
			{
				"name":"K04432  MAP2K3, MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]"
			},
			{
				"name":"K04430  MAP2K4, MKK4; mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]"
			},
			{
				"name":"K04463  MAP2K5, MEK5; mitogen-activated protein kinase kinase 5 [EC:2.7.12.2]"
			},
			{
				"name":"K04433  MAP2K6, MKK6; mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]"
			},
			{
				"name":"K04431  MAP2K7, MKK7; mitogen-activated protein kinase kinase 7 [EC:2.7.12.2]"
			},
			{
				"name":"K08294  MKK1_2; mitogen-activated protein kinase kinase [EC:2.7.12.2]"
			},
			{
				"name":"K11226  STE7; mitogen-activated protein kinase kinase [EC:2.7.12.2]"
			},
			{
				"name":"K11227  PBS2; mitogen-activated protein kinase kinase [EC:2.7.12.2]"
			},
			{
				"name":"K19763  JKK1; dual specificity mitogen-activated protein kinase kinase JKK-1 [EC:2.7.12.2]"
			},
			{
				"name":"K20602  MEK1, MKK1; mitogen-activated protein kinase kinase 1 [EC:2.7.12.2]"
			},
			{
				"name":"K20603  MKK2; mitogen-activated protein kinase kinase 2 [EC:2.7.12.2]"
			},
			{
				"name":"K20607  MKK3; mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]"
			},
			{
				"name":"K13413  MKK4_5; mitogen-activated protein kinase kinase 4\/5 [EC:2.7.12.2]"
			},
			{
				"name":"K20604  MKK9; mitogen-activated protein kinase kinase 9 [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"STE20 family",
			"children":[
			{
				"name":"K04408  MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K04414  MAP4K2, GCK; mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K04406  MAP4K3, GLK; mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K04407  MAP4K4, HGK; mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1]"
			},
			{
				"name":"K08833  MAP4K5, KHS1; mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"K04413  MINK; misshapen\/NIK-related kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08840  TNIK; TRAF2 and NCK interacting kinase [EC:2.7.11.1]"
			},
			{
				"name":"K16313  NRK; Nik-related protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08834  MYO3, DFNB30; myosin III [EC:2.7.11.1]"
			},
			{
				"name":"K08835  OXSR1, STK39; serine\/threonine-protein kinase OSR1\/STK39 [EC:2.7.11.1]"
			},
			{
				"name":"K04409  PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K04410  PAK2; p21-activated kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K05733  PAK3, MRX30; p21-activated kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K05734  PAK4; p21-activated kinase 4 [EC:2.7.11.1]"
			},
			{
				"name":"K05736  PAK5, PAK7; p21-activated kinase 5 [EC:2.7.11.1]"
			},
			{
				"name":"K05735  PAK6; p21-activated kinase 6 [EC:2.7.11.1]"
			},
			{
				"name":"K19833  CLA4; serine\/threonine-protein kinase CLA4 [EC:2.7.11.1]"
			},
			{
				"name":"K08836  SLK; STE20-like kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08837  STK10, LOK; serine\/threonine kinase 10 [EC:2.7.11.1]"
			},
			{
				"name":"K08271  STRADA, LYK5; STE20-related kinase adapter protein alpha"
			},
			{
				"name":"K17532  STRADB; STE20-related kinase adapter protein beta"
			},
			{
				"name":"K04412  STK3, MST2; serine\/threonine kinase 3"
			},
			{
				"name":"K04411  STK4, MST1; serine\/threonine kinase 4"
			},
			{
				"name":"K08838  STK24_25_MST4; serine\/threonine-protein kinase 24\/25\/MST4 [EC:2.7.11.1]"
			},
			{
				"name":"K04429  TAO; thousand and one amino acid protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K12771  SPS1; sporulation-specific protein 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"STE11 family",
			"children":[
			{
				"name":"K04416  MAP3K1, MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
			},
			{
				"name":"K04420  MAP3K2, MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]"
			},
			{
				"name":"K04421  MAP3K3, MEKK3; mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]"
			},
			{
				"name":"K04428  MAP3K4, MEKK4; mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]"
			},
			{
				"name":"K04426  MAP3K5, ASK1; mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]"
			},
			{
				"name":"K04425  MAP3K6, ASK2; mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25]"
			},
			{
				"name":"K13986  MAP3K15; mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25]"
			},
			{
				"name":"K17533  MAP3K19, YSK4; mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.25]"
			},
			{
				"name":"K13414  MEKK1; mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25]"
			},
			{
				"name":"K20605  MEKK2; mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]"
			},
			{
				"name":"K20606  ANP1; mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25]"
			},
			{
				"name":"K20716  MAPKKK17_18; mitogen-activated protein kinase kinase kinase 17\/18"
			},
			{
				"name":"K20717  YDA; mitogen-activated protein kinase kinase kinase YODA [EC:2.7.11.25]"
			},
			{
				"name":"K11228  STE11; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K04415  MAP3K8, COT; mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25]"
			},
			{
				"name":"K04466  MAP3K14, NIK; mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25]"
			},
			{
				"name":"K11229  BCK1; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]"
			},
			{
				"name":"K11230  SSK2; mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: TKL group",
		"children":[
		{
			"name":"IRAK family",
			"children":[
			{
				"name":"K04730  IRAK1; interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K04731  IRAK2; interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K04732  IRAK3; interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K04733  IRAK4; interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]"
			},
			{
				"name":"K13415  BRI1; protein brassinosteroid insensitive 1 [EC:2.7.10.1 2.7.11.1]"
			},
			{
				"name":"K13416  BAK1; brassinosteroid insensitive 1-associated receptor kinase 1 [EC:2.7.10.1 2.7.11.1]"
			},
			{
				"name":"K13417  SERK4, BKK1; somatic embryogenesis receptor kinase 4 [EC:2.7.10.1 2.7.11.1]"
			},
			{
				"name":"K13418  SERK1; somatic embryogenesis receptor kinase 1 [EC:2.7.10.1 2.7.11.1]"
			},
			{
				"name":"K13420  FLS2; LRR receptor-like serine\/threonine-protein kinase FLS2 [EC:2.7.11.1]"
			},
			{
				"name":"K13428  EFR; LRR receptor-like serine\/threonine-protein kinase EFR [EC:2.7.11.1]"
			},
			{
				"name":"K20718  ER; LRR receptor-like serine\/threonine-protein kinase ERECTA [EC:2.7.11.1]"
			},
			{
				"name":"K14500  BSK; BR-signaling kinase [EC:2.7.11.1]"
			},
			{
				"name":"K00924  TMK; receptor protein kinase TMK [EC:2.7.11.1]"
			},
			{
				"name":"K27625  PSKR1; phytosulfokine receptor 1 [EC:2.7.11.1 4.6.1.2]"
			},
			{
				"name":"K27626  PSKR2; phytosulfokine receptor 2 [EC:2.7.11.1]"
			},
			{
				"name":"K28089  PEPR; leucine-rich repeat receptor-like protein kinase PEPR [EC:2.7.11.1 4.6.1.2]"
			},
			{
				"name":"K28077  PRK; pollen receptor-like kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"LISK family [OT]",
			"children":[
			{
				"name":"K05743  LIMK1; LIM domain kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K05744  LIMK2; LIM domain kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K08841  TESK1; testis-specific kinase 1 [EC:2.7.12.1]"
			},
			{
				"name":"K08842  TESK2; testis-specific kinase 2 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"LRRK family",
			"children":[
			{
				"name":"K08843  LRRK1; leucine-rich repeat kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K08844  LRRK2; leucine-rich repeat kinase 2 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"MLK family",
			"children":[
			{
				"name":"K04427  MAP3K7, TAK1; mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25]"
			},
			{
				"name":"K04417  MAP3K9, MLK1; mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25]"
			},
			{
				"name":"K04418  MAP3K10, MLK2; mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25]"
			},
			{
				"name":"K04419  MAP3K11, MLK3; mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25]"
			},
			{
				"name":"K17534  MLK4, KIAA1804; mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25]"
			},
			{
				"name":"K04424  ZAK, MLTK; sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25]"
			},
			{
				"name":"K04423  MAP3K12, MUK; mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25]"
			},
			{
				"name":"K04422  MAP3K13, LZK; mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25]"
			},
			{
				"name":"K17535  TNNI3K; serine\/threonine-protein kinase TNNI3K [EC:2.7.11.1]"
			},
			{
				"name":"K06272  ILK; integrin-linked kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RAF family [OT]",
			"children":[
			{
				"name":"K08845  ARAF, ARAF1; A-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K04365  BRAF; B-Raf proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K04366  RAF1; RAF proto-oncogene serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K14958  KSR1; kinase suppressor of Ras 1"
			},
			{
				"name":"K18529  KSR2; kinase suppressor of Ras 2 [EC:2.7.11.1]"
			},
			{
				"name":"K14510  CTR1; serine\/threonine-protein kinase CTR1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"RIPK family [OT]",
			"children":[
			{
				"name":"K02861  RIPK1, RIP1; receptor-interacting serine\/threonine-protein kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K08846  RIPK2; receptor-interacting serine\/threonine-protein kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K08847  RIPK3; receptor-interacting serine\/threonine-protein kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K08848  RIPK4; receptor-interacting serine\/threonine-protein kinase 4 [EC:2.7.11.1]"
			},
			{
				"name":"K16289  ANKK1; ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1]"
			},
			{
				"name":"K16279  KEG; E3 ubiquitin-protein ligase KEG [EC:2.7.11.1 2.3.2.27]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K08849  MLKL; mixed lineage kinase domain-like [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Serine\/threonine kinases: Other",
		"children":[
		{
			"name":"RGC family [OT]",
			"children":[
			{
				"name":"K12323  NPR1, ANPRA; atrial natriuretic peptide receptor 1 [EC:4.6.1.2]"
			},
			{
				"name":"K12324  NPR2, ANPRB; atrial natriuretic peptide receptor 2 [EC:4.6.1.2]"
			},
			{
				"name":"K12320  GUCY2C; heat-stable enterotoxin receptor [EC:4.6.1.2]"
			},
			{
				"name":"K12321  GUCY2D_E; guanylate cyclase 2D\/E [EC:4.6.1.2]"
			},
			{
				"name":"K12322  GUCY2F; guanylate cyclase 2F [EC:4.6.1.2]"
			}
			]
		},
		{
			"name":"BUB family",
			"children":[
			{
				"name":"K02178  BUB1; checkpoint serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K06637  BUB1B, BUBR1, MAD3L; mitotic checkpoint serine\/threonine-protein kinase BUB1 beta [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Bud32 family",
			"children":[
			{
				"name":"K08851  TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
			},
			{
				"name":"K15904  kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase \/ protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]"
			}
			]
		},
		{
			"name":"CAMKK family",
			"children":[
			{
				"name":"K00908  CAMKK1; calcium\/calmodulin-dependent protein kinase kinase 1 [EC:2.7.11.17]"
			},
			{
				"name":"K07359  CAMKK2; calcium\/calmodulin-dependent protein kinase kinase 2 [EC:2.7.11.17]"
			}
			]
		},
		{
			"name":"CDC7 family",
			"children":[
			{
				"name":"K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"CK2 family",
			"children":[
			{
				"name":"K03097  CSNK2A; casein kinase II subunit alpha [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Haspin family",
			"children":[
			{
				"name":"K16315  GSG2; serine\/threonine-protein kinase haspin [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"IKK family [OT]",
			"children":[
			{
				"name":"K04467  IKBKA, IKKA, CHUK; inhibitor of nuclear factor kappa-B kinase subunit alpha [EC:2.7.11.10]"
			},
			{
				"name":"K07209  IKBKB, IKKB; inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10]"
			},
			{
				"name":"K07210  IKBKG, IKKG, NEMO; inhibitor of nuclear factor kappa-B kinase subunit gamma"
			},
			{
				"name":"K07211  IKBKE, IKKE; inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10]"
			},
			{
				"name":"K05410  TBK1; TANK-binding kinase 1 [EC:2.7.11.10]"
			}
			]
		},
		{
			"name":"IRE family",
			"children":[
			{
				"name":"K08852  ERN1; serine\/threonine-protein kinase\/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]"
			},
			{
				"name":"K11715  ERN2; serine\/threonine-protein kinase\/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-]"
			}
			]
		},
		{
			"name":"MOS family",
			"children":[
			{
				"name":"K04367  MOS; proto-oncogene serine\/threonine-protein kinase mos [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NAK family [OT]",
			"children":[
			{
				"name":"K08853  AAK; AP2-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08854  BMP2K, BIKE; BMP2 inducible kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08855  GAK; cyclin G-associated kinase [EC:2.7.11.1]"
			},
			{
				"name":"K08856  STK16; serine\/threonine kinase 16 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NEK family",
			"children":[
			{
				"name":"K08857  NEK1_4_5; serine\/threonine-protein kinase Nek1\/4\/5 [EC:2.7.11.1]"
			},
			{
				"name":"K20872  NEK2; serine\/threonine-protein kinase Nek2 [EC:2.7.11.1]"
			},
			{
				"name":"K20873  NEK3; serine\/threonine-protein kinase Nek3 [EC:2.7.11.1]"
			},
			{
				"name":"K20875  NEK6; serine\/threonine-protein kinase Nek6 [EC:2.7.11.34]"
			},
			{
				"name":"K20876  NEK7; serine\/threonine-protein kinase Nek7 [EC:2.7.11.34]"
			},
			{
				"name":"K20877  NEK8; serine\/threonine-protein kinase Nek8 [EC:2.7.11.1]"
			},
			{
				"name":"K20878  NEK9, NERCC1; serine\/threonine-protein kinase Nek9 [EC:2.7.11.38]"
			},
			{
				"name":"K20879  NEK10; serine\/threonine-protein kinase Nek10 [EC:2.7.11.1]"
			},
			{
				"name":"K20880  NEK11; serine\/threonine-protein kinase Nek11 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF1 family",
			"children":[
			{
				"name":"K08858  SBK; serine\/threonine-protein kinase SBK [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF2 family",
			"children":[
			{
				"name":"K05688  PINK1; PTEN induced putative kinase 1 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF3 family",
			"children":[
			{
				"name":"K17537  SGK223; tyrosine-protein kinase SgK223 [EC:2.7.10.2]"
			},
			{
				"name":"K17538  PEAK1, SGK269; pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"NKF4 family",
			"children":[
			{
				"name":"K08859  STK35, PDIK1, CLIK1; serine\/threonine kinase 35 [EC:2.7.11.1]"
			},
			{
				"name":"K17539  PDIK1L, CLIK1L; serine\/threonine-protein kinase PDIK1L [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"NKF5 family",
			"children":[
			{
				"name":"K17540 TEX14, SGK307; inactive serine\/threonine-protein kinase TEX14"
			}
			]
		},
		{
			"name":"NRBP family",
			"children":[
			{
				"name":"K08875  NRBP; nuclear receptor-binding protein"
			}
			]
		},
		{
			"name":"PEK family [OT]",
			"children":[
			{
				"name":"K16194  EIF2AK1; eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K16195  EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K08860  EIF2AK3, PERK; eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1]"
			},
			{
				"name":"K16196  EIF2AK4, GCN2; eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"PLK family [OT]",
			"children":[
			{
				"name":"K06631  PLK1; polo-like kinase 1 [EC:2.7.11.21]"
			},
			{
				"name":"K08861  PLK2; polo-like kinase 2 [EC:2.7.11.21]"
			},
			{
				"name":"K08862  PLK3, CNK; polo-like kinase 3 [EC:2.7.11.21]"
			},
			{
				"name":"K08863  PLK4; polo-like kinase 4 [EC:2.7.11.21]"
			}
			]
		},
		{
			"name":"SCY1 family [OT]",
			"children":[
			{
				"name":"K08876  SCYL1; SCY1-like protein 1"
			},
			{
				"name":"K17541  SCYL2; SCY1-like protein 2"
			},
			{
				"name":"K17542  SCYL3; SCY1-like protein 3"
			}
			]
		},
		{
			"name":"Slob family",
			"children":[
			{
				"name":"K17543  PXK; PX domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TBCK family",
			"children":[
			{
				"name":"K17544  TBCK; TBC domain-containing protein kinase-like protein"
			}
			]
		},
		{
			"name":"TLK family",
			"children":[
			{
				"name":"K08864  TLK; tousled-like kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TOPK family",
			"children":[
			{
				"name":"K08865  PBK; PDZ-binding kinase [EC:2.7.12.2]"
			}
			]
		},
		{
			"name":"TTK family",
			"children":[
			{
				"name":"K08866  TTK, MPS1; serine\/threonine-protein kinase TTK\/MPS1 [EC:2.7.12.1]"
			}
			]
		},
		{
			"name":"ULK family [OT]",
			"children":[
			{
				"name":"K06228  FU; fused [EC:2.7.11.1]"
			},
			{
				"name":"K21357  ULK1; serine\/threonine-protein kinase ULK1 [EC:2.7.11.1]"
			},
			{
				"name":"K08269  ULK2, ATG1; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
			},
			{
				"name":"K21358  ULK3; serine\/threonine-protein kinase ULK3 [EC:2.7.11.1]"
			},
			{
				"name":"K17545  ULK4; serine\/threonine-protein kinase ULK4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"VPS15 family",
			"children":[
			{
				"name":"K08333  PIK3R4, VPS15; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"WEE family",
			"children":[
			{
				"name":"K06633  PKMYT; membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1]"
			},
			{
				"name":"K06632  WEE1; wee1-like protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"Wnk family",
			"children":[
			{
				"name":"K08867  WNK, PRKWNK; WNK lysine deficient protein kinase [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"ABC1 family",
			"children":[
			{
				"name":"K08869  ADCK, ABC1; aarF domain-containing kinase"
			}
			]
		},
		{
			"name":"Alpha family [OT]",
			"children":[
			{
				"name":"K08868  ALPK; alpha-kinase"
			},
			{
				"name":"K04981  TRPM6, CHAK2; transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1]"
			},
			{
				"name":"K04982  TRPM7, CHAK1; transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1]"
			},
			{
				"name":"K08292  EEF2K; elongation factor 2 kinase [EC:2.7.11.20]"
			}
			]
		},
		{
			"name":"BCR family",
			"children":[
			{
				"name":"K08878  BCR1, BCR; breakpoint cluster region protein [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"BRD family [OT]",
			"children":[
			{
				"name":"K08871  BRD2; bromodomain-containing protein 2"
			},
			{
				"name":"K11721  BRD3; bromodomain-containing protein 3"
			},
			{
				"name":"K11722  BRD4; bromodomain-containing protein 4"
			},
			{
				"name":"K11724  BRDT; bromodomain testis-specific protein"
			}
			]
		},
		{
			"name":"FAST family",
			"children":[
			{
				"name":"K08290  FASTK; Fas-activated serine\/threonine kinase [EC:2.7.11.8]"
			}
			]
		},
		{
			"name":"G11 family",
			"children":[
			{
				"name":"K08880  STK19; serine\/threonine kinase 19 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"H11 family",
			"children":[
			{
				"name":"K08879  HSPB8; heat shock protein beta-8"
			}
			]
		},
		{
			"name":"PDHK family [OT]",
			"children":[
			{
				"name":"K12077  PDK1; pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2]"
			},
			{
				"name":"K00898  PDK2_3_4; pyruvate dehydrogenase kinase 2\/3\/4 [EC:2.7.11.2]"
			},
			{
				"name":"K00905  BCKDK; [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4]"
			}
			]
		},
		{
			"name":"PIKK family [OT]",
			"children":[
			{
				"name":"K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]"
			},
			{
				"name":"K06640  ATR; serine\/threonine-protein kinase ATR [EC:2.7.11.1]"
			},
			{
				"name":"K07203  MTOR, FRAP, TOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
			},
			{
				"name":"K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
			},
			{
				"name":"K08873  SMG1; serine\/threonine-protein kinase SMG1 [EC:2.7.11.1]"
			},
			{
				"name":"K08874  TRRAP; transformation\/transcription domain-associated protein"
			}
			]
		},
		{
			"name":"RIO family [OT]",
			"children":[
			{
				"name":"K07178  RIOK1; RIO kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K07179  RIOK2; RIO kinase 2 [EC:2.7.11.1]"
			},
			{
				"name":"K08872  RIOK3, SUDD; RIO kinase 3 [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TAF1 family",
			"children":[
			{
				"name":"K03125  TAF1; transcription initiation factor TFIID subunit 1 [EC:2.3.1.48 2.7.11.1]"
			},
			{
				"name":"K08060  CIITA; MHC class II transactivator [EC:2.7.11.1]"
			}
			]
		},
		{
			"name":"TIF1 family [OT]",
			"children":[
			{
				"name":"K08881  TRIM24, TIF1A; tripartite motif-containing protein 24 [EC:2.3.2.27]"
			},
			{
				"name":"K08882  TRIM28, TIF1B; tripartite motif-containing protein 28 [EC:2.3.2.27]"
			},
			{
				"name":"K08883  TRIM33, TIF1G; tripartite motif-containing protein 33 [EC:2.3.2.27]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K08877  UHMK1, KIS; serine\/threonine-protein kinase Kist [EC:2.7.11.1]"
			},
			{
				"name":"K11789  DCAF1, VPRBP; DDB1- and CUL4-associated factor 1 [EC:2.7.11.1]"
			},
			{
				"name":"K16316  STK31, TDRD8; serine\/threonine-protein kinase 31 [EC:2.7.11.1]"
			},
			{
				"name":"K17547  SGK196; glycoprotein-mannosyl O6-kinase [EC:2.7.1.183]"
			},
			{
				"name":"K16288  DSTYK, RIPK5; dual serine\/threonine and tyrosine protein kinase [EC:2.7.12.1]"
			},
			{
				"name":"K17546  STKLD1; serine\/threonine kinase-like domain-containing protein STKLD1"
			},
			{
				"name":"K13429  CERK1; chitin elicitor receptor kinase 1"
			},
			{
				"name":"K13430  PBS1; serine\/threonine-protein kinase PBS1 [EC:2.7.11.1]"
			},
			{
				"name":"K13435  PTO; serine\/threonine-protein kinase Pto"
			},
			{
				"name":"K13436  PTI1; pto-interacting protein 1 [EC:2.7.11.1]"
			},
			{
				"name":"K13437  XA21; receptor kinase-like protein"
			},
			{
				"name":"K16224  FRK1; senescence-induced receptor-like serine\/threonine-protein kinase"
			},
			{
				"name":"K16314  ELM1; serine\/threonine-protein kinase ELM1 [EC:2.7.11.1]"
			},
			{
				"name":"K21157  SAK1; SNF1-activating kinase 1 [EC:2.7.11.1]"
			},
			{
				"name":"K21158  TOS3; serine\/threonine-protein kinase TOS3 [EC:2.7.11.1]"
			},
			{
				"name":"K22009  MCK1; protein kinase MCK1"
			}
			]
		},
		{
			"name":"Bacterial family",
			"children":[
			{
				"name":"K11889  impN; type VI secretion system protein ImpN [EC:2.7.11.1]"
			},
			{
				"name":"K11912  ppkA; serine\/threonine-protein kinase PpkA [EC:2.7.11.1]"
			},
			{
				"name":"K14949  pknG; serine\/threonine-protein kinase PknG [EC:2.7.11.1]"
			},
			{
				"name":"K22893  pknH; serine\/threonine kinase PknH [EC:2.7.11.1]"
			},
			{
				"name":"K13419  pknK; serine\/threonine-protein kinase PknK [EC:2.7.11.1]"
			},
			{
				"name":"K12132  prkC, stkP; eukaryotic-like serine\/threonine-protein kinase [EC:2.7.11.1]"
			},
			{
				"name":"K23472  ypkA, yopO; serine\/threonine protein kinase YpkA [EC:2.7.11.1]"
			},
			{
				"name":"K07154  hipA; serine\/threonine-protein kinase HipA [EC:2.7.11.1]"
			},
			{
				"name":"K15486  legK1; serine\/threonine-protein kinase LegK1 [EC:2.7.1.-]"
			},
			{
				"name":"K17752  rsbT; serine\/threonine-protein kinase RsbT [EC:2.7.11.1]"
			},
			{
				"name":"K04757  rsbW; serine\/threonine-protein kinase RsbW [EC:2.7.11.1]"
			},
			{
				"name":"K08884  K08884; serine\/threonine protein kinase, bacterial [EC:2.7.11.1]"
			}
			]
		}
		]
	},
	{
		"name":"Receptor serine\/threonine kinases (RSTK): TKL group",
		"children":[
		{
			"name":"TGFBR1 family [OT]",
			"children":[
			{
				"name":"K04675  ACVR1, ALK2; activin receptor type-1 [EC:2.7.11.30]"
			},
			{
				"name":"K13594  ACVRL1, ALK1; activin receptor-like kinase 1 [EC:2.7.11.30]"
			},
			{
				"name":"K13567  ACVR1B, ALK4; activin receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"K13568  ACVR1C, ALK7; activin receptor type-1C [EC:2.7.11.30]"
			},
			{
				"name":"K04673  BMPR1A, ALK3, CD292; bone morphogenetic protein receptor type-1A [EC:2.7.11.30]"
			},
			{
				"name":"K13578  BMPR1B, ALK6, CDw293; bone morphogenetic protein receptor type-1B [EC:2.7.11.30]"
			},
			{
				"name":"K04674  TGFBR1, ALK5; TGF-beta receptor type-1 [EC:2.7.11.30]"
			}
			]
		},
		{
			"name":"TGFBR2 family [OT]",
			"children":[
			{
				"name":"K04670  ACVR2A; activin receptor type-2A [EC:2.7.11.30]"
			},
			{
				"name":"K13596  ACVR2B; activin receptor type-2B [EC:2.7.11.30]"
			},
			{
				"name":"K04672  AMHR2; anti-mullerian hormone receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"K04671  BMPR2; bone morphogenetic protein receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"K04388  TGFBR2; TGF-beta receptor type-2 [EC:2.7.11.30]"
			},
			{
				"name":"K04669  TGFBRX; TGF-beta receptor, other"
			}
			]
		}
		]
	},
	{
		"name":"Receptor tyrosine kinases (RTK)",
		"children":[
		{
			"name":"EGFR family [OT]",
			"children":[
			{
				"name":"K04361  EGFR, ERBB1; epidermal growth factor receptor [EC:2.7.10.1]"
			},
			{
				"name":"K05083  ERBB2, HER2, CD340; receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]"
			},
			{
				"name":"K05084  ERBB3, HER3; receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1]"
			},
			{
				"name":"K05085  ERBB4, HER4; receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"INSR family [OT]",
			"children":[
			{
				"name":"K05086  INSRR; insulin receptor-related receptor [EC:2.7.10.1]"
			},
			{
				"name":"K04527  INSR, CD220; insulin receptor [EC:2.7.10.1]"
			},
			{
				"name":"K05087  IGF1R, CD221; insulin-like growth factor 1 receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"PDGFR family [OT]",
			"children":[
			{
				"name":"K04363  PDGFRA, CD140A; platelet-derived growth factor receptor alpha [EC:2.7.10.1]"
			},
			{
				"name":"K05089  PDGFRB, CD140B; platelet-derived growth factor receptor beta [EC:2.7.10.1]"
			},
			{
				"name":"K05090  CSF1R, FMS, CD115; macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1]"
			},
			{
				"name":"K05091  KIT, SCFR, CD117; proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]"
			},
			{
				"name":"K05092  FLT3, FLK2, CD135; fms-related tyrosine kinase 3 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"FGFR family [OT]",
			"children":[
			{
				"name":"K04362  FGFR1, CD331; fibroblast growth factor receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"K05093  FGFR2, CD332; fibroblast growth factor receptor 2 [EC:2.7.10.1]"
			},
			{
				"name":"K05094  FGFR3, CD333; fibroblast growth factor receptor 3 [EC:2.7.10.1]"
			},
			{
				"name":"K05095  FGFR4, CD334; fibroblast growth factor receptor 4 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"VEGFR family [OT]",
			"children":[
			{
				"name":"K05096  FLT1, VEGFR1; FMS-like tyrosine kinase 1 [EC:2.7.10.1]"
			},
			{
				"name":"K05097  FLT4, VEGFR3; FMS-like tyrosine kinase 4 [EC:2.7.10.1]"
			},
			{
				"name":"K05098  KDR, VEGFR2, CD309; kinase insert domain protein receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MET family",
			"children":[
			{
				"name":"K05099  MET, HGFR; proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1]"
			},
			{
				"name":"K05100  MST1R, RON, CD136; macrophage-stimulating 1 receptor [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"TRK family [OT]",
			"children":[
			{
				"name":"K03176  NTRK1, TRKA; neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1]"
			},
			{
				"name":"K04360  NTRK2, TRKB; neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1]"
			},
			{
				"name":"K05101  NTRK3, TRKC; neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"EPH family [OT]",
			"children":[
			{
				"name":"K05102  EPHA1, EPH; Eph receptor A1 [EC:2.7.10.1]"
			},
			{
				"name":"K05103  EPHA2, ECK; Eph receptor A2 [EC:2.7.10.1]"
			},
			{
				"name":"K05104  EPHA3, HEK, TYRO4; Eph receptor A3 [EC:2.7.10.1]"
			},
			{
				"name":"K05105  EPHA4, SEK, TYRO1; Eph receptor A4 [EC:2.7.10.1]"
			},
			{
				"name":"K05106  EPHA5, EHK1, TYRO4; Eph receptor A5 [EC:2.7.10.1]"
			},
			{
				"name":"K05107  EPHA6, EHK2; Eph receptor A6 [EC:2.7.10.1]"
			},
			{
				"name":"K05108  EPHA7, EHK3, HEK11; EphA7 [EC:2.7.10.1]"
			},
			{
				"name":"K05109  EPHA8, EEK; Eph receptor A8 [EC:2.7.10.1]"
			},
			{
				"name":"K08897  EPHA10; Eph receptor A10 [EC:2.7.10.1]"
			},
			{
				"name":"K05110  EPHB1, ELK, NET; Eph receptor B1 [EC:2.7.10.1]"
			},
			{
				"name":"K05111  EPHB2, ERK, DRT; Eph receptor B2 [EC:2.7.10.1]"
			},
			{
				"name":"K05112  EPHB3, HEK2, ETK2; Eph receptor B3 [EC:2.7.10.1]"
			},
			{
				"name":"K05113  EPHB4, HTK; Eph receptor B4 [EC:2.7.10.1]"
			},
			{
				"name":"K05114  EPHB6; Eph receptor B6 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"AXL family",
			"children":[
			{
				"name":"K05115  AXL, UFO; AXL receptor tyrosine kinase [EC:2.7.10.1]"
			},
			{
				"name":"K05116  TYRO3, RSE; TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1]"
			},
			{
				"name":"K05117  MERTK, MER; c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ALK family",
			"children":[
			{
				"name":"K05119  ALK, CD246; anaplastic lymphoma kinase [EC:2.7.10.1]"
			},
			{
				"name":"K05118  LTK; leukocyte tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"TIE family",
			"children":[
			{
				"name":"K05120  TIE1; tyrosine kinase receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"K05121  TEK, TIE2, CD202; endothelial-specific receptor tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ROR family",
			"children":[
			{
				"name":"K05122  ROR1, NTRKR1; receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1]"
			},
			{
				"name":"K05123  ROR2, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"DDR family",
			"children":[
			{
				"name":"K05124  DDR1, NEP, CD167a; discoidin domain receptor family member 1 [EC:2.7.10.1]"
			},
			{
				"name":"K05125  DDR2, TKT, CD167b; discoidin domain receptor family member 2 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RET family",
			"children":[
			{
				"name":"K05126  RET; proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"ROS family",
			"children":[
			{
				"name":"K05088  ROS1; proto-oncogene tyrosine-protein kinase ROS [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"CCK family",
			"children":[
			{
				"name":"K05127  PTK7, CCK4; PTK7 protein tyrosine kinase 7 [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"RYK family",
			"children":[
			{
				"name":"K05128  RYK; RYK receptor-like tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"MUSK family",
			"children":[
			{
				"name":"K05129  MUSK; muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1]"
			}
			]
		},
		{
			"name":"LMR family [OT]",
			"children":[
			{
				"name":"K17480  AATK, LMTK1; lemur tyrosine kinase 1 [EC:2.7.10.1]"
			},
			{
				"name":"K08898  LMTK2; lemur tyrosine kinase 2 [EC:2.7.10.1]"
			},
			{
				"name":"K08899  LMTK3; lemur tyrosine kinase 3 [EC:2.7.10.1]"
			}
			]
		}
		]
	},
	{
		"name":"Non-receptor tyrosine kinases",
		"children":[
		{
			"name":"ABL family",
			"children":[
			{
				"name":"K06619  ABL1; abelson tyrosine-protein kinase 1 [EC:2.7.10.2]"
			},
			{
				"name":"K08887  ABL2; abelson tyrosine-protein kinase 2 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"ACK family",
			"children":[
			{
				"name":"K08885  TNK1; non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2]"
			},
			{
				"name":"K08886  TNK2, ACK1; activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1]"
			}
			]
		},
		{
			"name":"CSK family",
			"children":[
			{
				"name":"K05728  CSK; C-terminal Src kinase [EC:2.7.10.4]"
			},
			{
				"name":"K08888  MATK; megakaryocyte-associated tyrosine kinase [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"FAK family",
			"children":[
			{
				"name":"K05725  PTK2, FAK; focal adhesion kinase 1 [EC:2.7.10.2]"
			},
			{
				"name":"K05871  PTK2B, FAK2; focal adhesion kinase 2 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"FES family",
			"children":[
			{
				"name":"K07527  FES, FPS; tyrosine-protein kinase Fes\/Fps [EC:2.7.10.2]"
			},
			{
				"name":"K08889  FER, TYK3; tyrosine-protein kinase Fer [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"JAK family [OT]",
			"children":[
			{
				"name":"K11217  JAK1; Janus kinase 1 [EC:2.7.10.2]"
			},
			{
				"name":"K04447  JAK2; Janus kinase 2 [EC:2.7.10.2]"
			},
			{
				"name":"K11218  JAK3; Janus kinase 3 [EC:2.7.10.2]"
			},
			{
				"name":"K11219  TYK2; non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SRC family",
			"children":[
			{
				"name":"K08890  BLK; B lymphoid tyrosine kinase [EC:2.7.10.2]"
			},
			{
				"name":"K08891  FGR, SRC2; tyrosine-protein kinase Fgr [EC:2.7.10.2]"
			},
			{
				"name":"K08892  FRK, PTK5; fyn-related kinase [EC:2.7.10.2]"
			},
			{
				"name":"K05703  FYN; tyrosine-protein kinase Fyn [EC:2.7.10.2]"
			},
			{
				"name":"K08893  HCK; hemopoietic cell kinase [EC:2.7.10.2]"
			},
			{
				"name":"K05854  LYN; tyrosine-protein kinase Lyn [EC:2.7.10.2]"
			},
			{
				"name":"K05856  LCK; lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2]"
			},
			{
				"name":"K08894  PTK6, BRK; protein tyrosine kinase 6 [EC:2.7.10.2]"
			},
			{
				"name":"K05704  SRC; tyrosine-protein kinase Src [EC:2.7.10.2]"
			},
			{
				"name":"K08895  SRMS; tyrosine-protein kinase Srms [EC:2.7.10.2]"
			},
			{
				"name":"K05705  YES1; tyrosine-protein kinase Yes [EC:2.7.10.2]"
			},
			{
				"name":"K17511  YRK; proto-oncogene tyrosine-protein kinase YRK [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"TEC family",
			"children":[
			{
				"name":"K08896  BMX, ETK; cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2]"
			},
			{
				"name":"K07370  BTK; Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2]"
			},
			{
				"name":"K07363  ITK; IL2-inducible T-cell kinase [EC:2.7.10.2]"
			},
			{
				"name":"K07364  TEC; tyrosine-protein kinase Tec [EC:2.7.10.2]"
			},
			{
				"name":"K08016  TXK, RLK; tyrosine-protein kinase TXK [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"SYK family",
			"children":[
			{
				"name":"K05855  SYK; spleen tyrosine kinase [EC:2.7.10.2]"
			},
			{
				"name":"K07360  ZAP70; tyrosine-protein kinase ZAP-70 [EC:2.7.10.2]"
			},
			{
				"name":"K17512  SHARK; tyrosine-protein kinase shark [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K17510  STYK1; tyrosine-protein kinase STYK1 [EC:2.7.10.2]"
			},
			{
				"name":"K17548  PKDCC; extracellular tyrosine-protein kinase PKDCC  [EC:2.7.10.2]"
			}
			]
		},
		{
			"name":"Bacterial",
			"children":[
			{
				"name":"K16692  etk-wzc; tyrosine-protein kinase Etk\/Wzc [EC:2.7.10.3]"
			},
			{
				"name":"K16554  exoP, vpsO; polysaccharide biosynthesis transport protein [EC:2.7.10.3]"
			},
			{
				"name":"K00903  epsB, capB; protein-tyrosine kinase [EC:2.7.10.3]"
			},
			{
				"name":"K25588  K25588; tyrosine-protein kinase [EC:2.7.10.3]"
			}
			]
		}
		]
	},
	{
		"name":"Histidine kinases",
		"children":[
		{
			"name":"OmpR family",
			"children":[
			{
				"name":"K07636  phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]"
			},
			{
				"name":"K07768  senX3; two-component system, OmpR family, sensor histidine kinase SenX3 [EC:2.7.13.3]"
			},
			{
				"name":"K07637  phoQ; two-component system, OmpR family, sensor histidine kinase PhoQ [EC:2.7.13.3]"
			},
			{
				"name":"K07638  envZ; two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ [EC:2.7.13.3]"
			},
			{
				"name":"K07639  rstB; two-component system, OmpR family, sensor histidine kinase RstB [EC:2.7.13.3]"
			},
			{
				"name":"K07640  cpxA; two-component system, OmpR family, sensor histidine kinase CpxA [EC:2.7.13.3]"
			},
			{
				"name":"K07650  cssS; two-component system, OmpR family, sensor histidine kinase CssS [EC:2.7.13.3]"
			},
			{
				"name":"K07641  creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3]"
			},
			{
				"name":"K07642  baeS, smeS; two-component system, OmpR family, sensor histidine kinase BaeS [EC:2.7.13.3]"
			},
			{
				"name":"K07643  basS; two-component system, OmpR family, sensor histidine kinase BasS [EC:2.7.13.3]"
			},
			{
				"name":"K07644  cusS, copS, silS; two-component system, OmpR family, heavy metal sensor histidine kinase CusS [EC:2.7.13.3]"
			},
			{
				"name":"K29156  crdS; two-component system, OmpR family, copper resistance sensor histidine kinase CrdS [EC:2.7.13.3]"
			},
			{
				"name":"K29146  hprS; two-component system, OmpR family, sensor histidine kinase HprS [EC:2.7.13.3]"
			},
			{
				"name":"K07645  qseC; two-component system, OmpR family, sensor histidine kinase QseC [EC:2.7.13.3]"
			},
			{
				"name":"K07646  kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]"
			},
			{
				"name":"K07647  torS; two-component system, OmpR family, sensor histidine kinase TorS [EC:2.7.13.3]"
			},
			{
				"name":"K07648  arcB; two-component system, OmpR family, aerobic respiration control sensor histidine kinase ArcB [EC:2.7.13.3]"
			},
			{
				"name":"K07649  tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]"
			},
			{
				"name":"K07651  resE; two-component system, OmpR family, sensor histidine kinase ResE [EC:2.7.13.3]"
			},
			{
				"name":"K07652  vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]"
			},
			{
				"name":"K07653  mprB; two-component system, OmpR family, sensor histidine kinase MprB [EC:2.7.13.3]"
			},
			{
				"name":"K07654  mtrB; two-component system, OmpR family, sensor histidine kinase MtrB [EC:2.7.13.3]"
			},
			{
				"name":"K07655  prrB; two-component system, OmpR family, sensor histidine kinase PrrB [EC:2.7.13.3]"
			},
			{
				"name":"K07656  trcS; two-component system, OmpR family, sensor histidine kinase TrcS [EC:2.7.13.3]"
			},
			{
				"name":"K11328  nrsS, rppB; two-component system, OmpR family, Ni(II)-sensor and\/or redox sensor kinase NrsS [EC:2.7.13.3]"
			},
			{
				"name":"K11520  manS; two-component system, OmpR family, manganese sensing sensor histidine kinase [EC:2.7.13.3]"
			},
			{
				"name":"K07769  nblS, dfr, dspA, hik33; two-component system, OmpR family, sensor histidine kinase NblS [EC:2.7.13.3]"
			},
			{
				"name":"K08479  sasA; two-component system, OmpR family, clock-associated histidine kinase SasA [EC:2.7.13.3]"
			},
			{
				"name":"K10681  saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]"
			},
			{
				"name":"K11629  bceS; two-component system, OmpR family, bacitracin resistance sensor histidine kinase BceS [EC:2.7.13.3]"
			},
			{
				"name":"K19077  graS; two-component system, OmpR family, sensor histidine kinase GraS [EC:2.7.13.3]"
			},
			{
				"name":"K19081  braS, bceS; two-component system, OmpR family, sensor histidine kinase BraS\/BceS [EC:2.7.13.3]"
			},
			{
				"name":"K11633  yxdK; two-component system, OmpR family, sensor histidine kinase YxdK [EC:2.7.13.3]"
			},
			{
				"name":"K14980  chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]"
			},
			{
				"name":"K14982  ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]"
			},
			{
				"name":"K18072  parS; two-component system, OmpR family, sensor kinase ParS [EC:2.7.13.3]"
			},
			{
				"name":"K18143  adeS; two-component system, OmpR family, sensor histidine kinase AdeS [EC:2.7.13.3]"
			},
			{
				"name":"K18345  vanSB, vanS, vanSD; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]"
			},
			{
				"name":"K18350  vanSC, vanSE, vanSG; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]"
			},
			{
				"name":"K18351  vanSAc; two-component system, OmpR family, sensor histidine kinase VanS [EC:2.7.13.3]"
			},
			{
				"name":"K18940  arlS; two-component system, OmpR family, sensor histidine kinase ArlS [EC:2.7.13.3]"
			},
			{
				"name":"K18986  ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]"
			},
			{
				"name":"K19609  pfeS, pirS; two-component system, OmpR family, sensor histidine kinase PfeS [EC:2.7.13.3]"
			},
			{
				"name":"K20487  nisK, spaK; two-component system, OmpR family, lantibiotic biosynthesis sensor histidine kinase NisK\/SpaK [EC:2.7.13.3]"
			},
			{
				"name":"K29137  qarB; two-component system, OmpR family, sensor histidine kinase QarB [EC:2.7.13.3]"
			},
			{
				"name":"K29154  hssS; two-component system, OmpR family, heme sensor histidine kinase HssS [EC:2.7.13.3]"
			},
			{
				"name":"K02484  K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NarL family",
			"children":[
			{
				"name":"K07673  narX; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarX [EC:2.7.13.3]"
			},
			{
				"name":"K07674  narQ; two-component system, NarL family, nitrate\/nitrite sensor histidine kinase NarQ [EC:2.7.13.3]"
			},
			{
				"name":"K07675  uhpB; two-component system, NarL family, sensor histidine kinase UhpB [EC:2.7.13.3]"
			},
			{
				"name":"K20263  fusK; two-component system, NarL family, sensor histidine kinase FusK [EC:2.7.13.3]"
			},
			{
				"name":"K07676  rcsD; two-component system, NarL family, sensor histidine kinase RcsD [EC:2.7.13.3]"
			},
			{
				"name":"K07677  rcsC; two-component system, NarL family, capsular synthesis sensor histidine kinase RcsC [EC:2.7.13.3]"
			},
			{
				"name":"K07678  barA, gacS, varS; two-component system, NarL family, sensor histidine kinase BarA [EC:2.7.13.3]"
			},
			{
				"name":"K07679  evgS, bvgS; two-component system, NarL family, sensor histidine kinase EvgS [EC:2.7.13.3]"
			},
			{
				"name":"K07680  comP; two-component system, NarL family, sensor histidine kinase ComP [EC:2.7.13.3]"
			},
			{
				"name":"K07777  degS; two-component system, NarL family, sensor histidine kinase DegS [EC:2.7.13.3]"
			},
			{
				"name":"K07778  desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]"
			},
			{
				"name":"K07681  vraS; two-component system, NarL family, vancomycin resistance sensor histidine kinase VraS [EC:2.7.13.3]"
			},
			{
				"name":"K11617  liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]"
			},
			{
				"name":"K07682  devS; two-component system, NarL family, sensor histidine kinase DevS [EC:2.7.13.3]"
			},
			{
				"name":"K27105  dosT; two-component system, NarL family, sensor histidine kinase DosT [EC:2.7.13.3]"
			},
			{
				"name":"K07683  nreB; two-component system, NarL family, sensor histidine kinase NreB [EC:2.7.13.3]"
			},
			{
				"name":"K11623  ydfH; two-component system, NarL family, sensor histidine kinase YdfH [EC:2.7.13.3]"
			},
			{
				"name":"K14988  salK; two-component system, NarL family, secretion system sensor histidine kinase SalK"
			},
			{
				"name":"K27076  pprA; two-component system, NarL family, sensor histidine kinase PprA [EC:2.7.13.3]"
			},
			{
				"name":"K02480  K02480; two-component system, NarL family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Spo family [OT]",
			"children":[
			{
				"name":"K02491  kinA; two-component system, sporulation sensor kinase A [EC:2.7.13.3]"
			},
			{
				"name":"K07697  kinB; two-component system, sporulation sensor kinase B [EC:2.7.13.3]"
			},
			{
				"name":"K07698  kinC; two-component system, sporulation sensor kinase C [EC:2.7.13.3]"
			},
			{
				"name":"K13532  kinD; two-component system, sporulation sensor kinase D [EC:2.7.13.3]"
			},
			{
				"name":"K13533  kinE; two-component system, sporulation sensor kinase E [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"CitB family [OT]",
			"children":[
			{
				"name":"K07700  dpiB, citA; two-component system, CitB family, cit operon sensor histidine kinase CitA [EC:2.7.13.3]"
			},
			{
				"name":"K11637  citS; two-component system, CitB family, sensor histidine kinase CitS [EC:2.7.13.3]"
			},
			{
				"name":"K07701  dcuS; two-component system, CitB family, sensor histidine kinase DcuS [EC:2.7.13.3]"
			},
			{
				"name":"K11691  K11691, dctS; two-component system, CitB family, sensor histidine kinase DctS [EC:2.7.13.3]"
			},
			{
				"name":"K11614  yufL, malK; two-component system, CitB family, sensor histidine kinase MalK [EC:2.7.13.3]"
			},
			{
				"name":"K02476  K02476; two-component system, CitB family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"LytTR family [OT]",
			"children":[
			{
				"name":"K07704  lytS; two-component system, LytTR family, sensor histidine kinase LytS [EC:2.7.13.3]"
			},
			{
				"name":"K08082  algZ; two-component system, LytTR family, sensor histidine kinase AlgZ [EC:2.7.13.3]"
			},
			{
				"name":"K11640  natK; two-component system, LytTR family, sensor histidine kinase NatK [EC:2.7.13.3]"
			},
			{
				"name":"K07706  agrC, blpH, fsrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]"
			},
			{
				"name":"K20339  agrC2; two-component system, LytTR family, sensor histidine kinase AgrC2 [EC:2.7.13.3]"
			},
			{
				"name":"K12294  comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]"
			},
			{
				"name":"K27882  btsS; two-component system, LytTR family, low-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"K27884  pyrS; two-component system, LytTR family, high-concentration pyruvate sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"K02478  K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"NtrC family",
			"children":[
			{
				"name":"K07708  glnL, ntrB; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]"
			},
			{
				"name":"K13598  ntrY; two-component system, NtrC family, nitrogen regulation sensor histidine kinase NtrY [EC:2.7.13.3]"
			},
			{
				"name":"K07709  zraS, hydH; two-component system, NtrC family, sensor histidine kinase HydH [EC:2.7.13.3]"
			},
			{
				"name":"K07710  atoS; two-component system, NtrC family, sensor histidine kinase AtoS [EC:2.7.13.3]"
			},
			{
				"name":"K02668  pilS, pehS; two-component system, NtrC family, sensor histidine kinase PilS [EC:2.7.13.3]"
			},
			{
				"name":"K07711  glrK, qseE; two-component system, NtrC family, sensor histidine kinase GlrK [EC:2.7.13.3]"
			},
			{
				"name":"K08475  pgtB; two-component system, NtrC family, phosphoglycerate transport system sensor histidine kinase PgtB [EC:2.7.13.3]"
			},
			{
				"name":"K10125  dctB; two-component system, NtrC family, C4-dicarboxylate transport sensor histidine kinase DctB [EC:2.7.13.3]"
			},
			{
				"name":"K11383  kinB; two-component system, NtrC family, sensor histidine kinase KinB [EC:2.7.13.3]"
			},
			{
				"name":"K19661  hupT, hoxJ; two-component system, NtrC family, sensor histidine kinase HupT\/HoxJ [EC:2.7.13.3]"
			},
			{
				"name":"K02482  flgS; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"CheA family [OT]",
			"children":[
			{
				"name":"K03407  cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]"
			},
			{
				"name":"K06596  chpA; chemosensory pili system protein ChpA (sensor histidine kinase\/response regulator)"
			},
			{
				"name":"K11526  pixL; two-component system, chemotaxis family, sensor histidine kinase and response regulator PixL"
			},
			{
				"name":"K13490  wspE; two-component system, chemotaxis family, sensor histidine kinase and response regulator WspE"
			},
			{
				"name":"K11354  cph1; two-component system, chemotaxis family, sensor kinase Cph1 [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Cell cycle family [OT]",
			"children":[
			{
				"name":"K07716  pleC; two-component system, cell cycle sensor histidine kinase PleC [EC:2.7.13.3]"
			},
			{
				"name":"K11357  divJ; two-component system, cell cycle sensor histidine kinase DivJ [EC:2.7.13.3]"
			},
			{
				"name":"K13587  cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]"
			},
			{
				"name":"K02489  hk1; two-component system, glycerol uptake and utilization sensor kinase [EC:2.7.13.3]"
			}
			]
		},
		{
			"name":"Lux family [OT]",
			"children":[
			{
				"name":"K10909  luxQ; two-component system, autoinducer 2 sensor kinase\/phosphatase LuxQ [EC:2.7.13.3 3.1.3.-]"
			},
			{
				"name":"K10916  cqsS; two-component system, CAI-1 autoinducer sensor kinase\/phosphatase CqsS [EC:2.7.13.3 3.1.3.-]"
			},
			{
				"name":"K15850  luxN; two-component system, autoinducer 1 sensor kinase\/phosphatase LuxN [EC:2.7.13.3 3.1.3.-]"
			}
			]
		},
		{
			"name":"LuxR family [OT]",
			"children":[
			{
				"name":"K11711  dctS; two-component system, LuxR family, sensor histidine kinase DctS [EC:2.7.13.3]"
			},
			{
				"name":"K13040  ttrS; two-component system, LuxR family, sensor histidine kinase TtrS [EC:2.7.13.3]"
			},
			{
				"name":"K14986  fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]"
			},
			{
				"name":"K14978  ssrA; two-component system, LuxR family, secretion system sensor histidine kinase SsrA"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K10942  flrB, fleS, flaL; two-component system, sensor histidine kinase FlrB [EC:2.7.13.3]"
			},
			{
				"name":"K11231  SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]"
			},
			{
				"name":"K19690  CHK1; osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]"
			},
			{
				"name":"K19691  NIK1, TCSC; osomolarity two-component system, sensor histidine kinase NIK1 [EC:2.7.13.3]"
			},
			{
				"name":"K19692  TCSA; osomolarity two-component system, sensor histidine kinase TcsA [EC:2.7.13.3]"
			},
			{
				"name":"K10715  rpfC; two-component system, sensor histidine kinase RpfC [EC:2.7.13.3]"
			},
			{
				"name":"K07717  glnK; two-component system, sensor histidine kinase GlnK [EC:2.7.13.3]"
			},
			{
				"name":"K25212  hptS; two-component system, sensor histidine kinase HptS [EC:2.7.13.3]"
			},
			{
				"name":"K07718  yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]"
			},
			{
				"name":"K11356  cikA; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]"
			},
			{
				"name":"K15011  regB, regS, actS; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]"
			},
			{
				"name":"K19616  fitF; two-component system, sensor histidine kinase and response regulator FitF [EC:2.7.13.3]"
			},
			{
				"name":"K19621  phcS; two-component system, sensor histidine kinase PhcS [EC:2.7.13.3]"
			},
			{
				"name":"K20973  sagS; two-component system, sensor histidine kinase SagS [EC:2.7.13.3]"
			},
			{
				"name":"K20974  K20974; two-component system, sensor histidine kinase [EC:2.7.13.3]"
			},
			{
				"name":"K20975  K20975; two-component system, sensor histidine kinase [EC:2.7.13.3]"
			},
			{
				"name":"K00936  pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]"
			},
			{
				"name":"K19694  chiS; two-component system, sensor histidine kinase ChiS"
			},
			{
				"name":"K20971  ladS; two-component system, sensor histidine kinase LadS"
			},
			{
				"name":"K20972  retS; two-component system, sensor histidine kinase RetS"
			},
			{
				"name":"K02486  K02486; two-component system, sensor kinase [EC:2.7.13.3]"
			},
			{
				"name":"K11527  K11527; two-component system, sensor histidine kinase and response regulator [EC:2.7.13.3]"
			}
			]
		}
		]
	}
	]
}