{
	"name":"ko01004",
	"children":[
	{
		"name":"Fatty acid synthase",
		"children":[
		{
			"name":"Animal type",
			"children":[
			{
				"name":"K00665  FASN; fatty acid synthase, animal type [EC:2.3.1.85]"
			}
			]
		},
		{
			"name":"Yeast type",
			"children":[
			{
				"name":"K00668  FAS1; fatty acid synthase subunit beta, fungi type [EC:2.3.1.86]"
			},
			{
				"name":"K00667  FAS2; fatty acid synthase subunit alpha, fungi type [EC:2.3.1.86]"
			}
			]
		},
		{
			"name":"Bacteria type",
			"children":[
			{
				"name":"K11533  fas; fatty acid synthase, bacteria type [EC:2.3.1.-]"
			}
			]
		},
		{
			"name":"Component type",
			"children":[
			{
				"name":"K00645  fabD, MCAT, MCT1; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]"
			},
			{
				"name":"K00648  fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]"
			},
			{
				"name":"K18473  fabY; acetoacetyl-[acyl-carrier protein] synthase [EC:2.3.1.180]"
			},
			{
				"name":"K00647  fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]"
			},
			{
				"name":"K09458  fabF, OXSM, CEM1; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]"
			},
			{
				"name":"K00059  fabG, OAR1; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]"
			},
			{
				"name":"K01716  fabA; 3-hydroxyacyl-[acyl-carrier protein] dehydratase \/ trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:4.2.1.59 5.3.3.14]"
			},
			{
				"name":"K02372  fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]"
			},
			{
				"name":"K16363  lpxC-fabZ; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase \/ 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:3.5.1.108 4.2.1.59]"
			},
			{
				"name":"K00208  fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]"
			},
			{
				"name":"K02371  fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]"
			},
			{
				"name":"K10780  fabL; enoyl-[acyl-carrier protein] reductase III [EC:1.3.1.104]"
			},
			{
				"name":"K00209  fabV, ter; enoyl-[acyl-carrier protein] reductase \/ trans-2-enoyl-CoA reductase (NAD+) [EC:1.3.1.9 1.3.1.44]"
			},
			{
				"name":"K18474  fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]"
			},
			{
				"name":"K10251  HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase \/ very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330]"
			},
			{
				"name":"K10703  HACD, PHS1, PAS2; very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134]"
			},
			{
				"name":"K07753  PECR; peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38]"
			},
			{
				"name":"K10258  TER, TSC13, CER10; very-long-chain enoyl-CoA reductase [EC:1.3.1.93]"
			},
			{
				"name":"K01071  MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]"
			},
			{
				"name":"K10782  FATA; fatty acyl-ACP thioesterase A [EC:3.1.2.14]"
			},
			{
				"name":"K10781  FATB; fatty acyl-ACP thioesterase B [EC:3.1.2.14 3.1.2.21]"
			},
			{
				"name":"K01074  PPT; palmitoyl-protein thioesterase [EC:3.1.2.22]"
			},
			{
				"name":"K01068  ACOT1_2_4; acyl-coenzyme A thioesterase 1\/2\/4 [EC:3.1.2.2]"
			},
			{
				"name":"K11993  ACOT6; acyl-CoA thioesterase 6 [EC:3.1.2.-]"
			},
			{
				"name":"K17360  ACOT7; acyl-coenzyme A thioesterase 7 [EC:3.1.2.2]"
			},
			{
				"name":"K17361  ACOT9; acyl-coenzyme A thioesterase 9 [EC:3.1.2.-]"
			},
			{
				"name":"K12417  ACOT11; acyl-CoA thioesteraes 11 [EC:3.1.2.-]"
			},
			{
				"name":"K17362  ACOT13; acyl-coenzyme A thioesterase 13 [EC:3.1.2.-]"
			},
			{
				"name":"K10804  tesA; acyl-CoA thioesterase I [EC:3.1.2.- 3.1.2.2 3.1.1.2 3.1.1.5]"
			},
			{
				"name":"K10805  tesB; acyl-CoA thioesterase II [EC:3.1.2.20]"
			},
			{
				"name":"K12500  tesC; thioesterase III [EC:3.1.2.-]"
			},
			{
				"name":"K10806  yciA; acyl-CoA thioesterase [EC:3.1.2.-]"
			},
			{
				"name":"K01073  yigI; acyl-CoA thioesterase [EC:3.1.2.-]"
			},
			{
				"name":"K11608  mtfabH; mycobacterial beta-ketoacyl-[acyl-carrier protein] synthase III [EC:2.3.1.301]"
			},
			{
				"name":"K11609  kasA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase I [EC:2.3.1.293]"
			},
			{
				"name":"K27070  kasB; meromycolic acid 3-oxoacyl-[acyl-carrier protein] synthase II [EC:2.3.1.294]"
			},
			{
				"name":"K11610  mabA; meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-]"
			},
			{
				"name":"K27071  hadA; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadA [EC:4.2.1.-]"
			},
			{
				"name":"K27072  hadB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadB [EC:4.2.1.-]"
			},
			{
				"name":"K27689  hadAB; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadAB [EC:4.2.1.-]"
			},
			{
				"name":"K27073  hadC; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadC [EC:4.2.1.-]"
			},
			{
				"name":"K27074  hadD; meromycolic acid (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase HadD [EC:4.2.1.-]"
			},
			{
				"name":"K11611  inhA; meromycolic acid enoyl-[acyl-carrier protein] reductase [EC:1.3.1.118]"
			},
			{
				"name":"K27985  nasA; long-chain acyl-[acp]:L-phenylalanine N-acyltransferase [EC:2.3.1.327]"
			},
			{
				"name":"K27986  nasB; branched-chain 2-oxoacid:malonyl-[acyl-carrier protein] acyltransferase [EC:2.3.1.328]"
			}
			]
		}
		]
	},
	{
		"name":"Desaturase",
		"children":[
		{
			"name":"First",
			"children":[
			{
				"name":"K00507  SCD, desC; stearoyl-CoA desaturase (Delta-9 desaturase) [EC:1.14.19.1]"
			},
			{
				"name":"K03921  FAB2, SSI2, desA1; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.11 1.14.19.26]"
			},
			{
				"name":"K03922  desA2; acyl-[acyl-carrier protein] desaturase [EC:1.14.19.2 1.14.19.-]"
			},
			{
				"name":"K22769  desA3; NADPH-dependent stearoyl-CoA 9-desaturase [EC:1.14.19.-]"
			}
			]
		},
		{
			"name":"Omega",
			"children":[
			{
				"name":"K10256  FAD2; omega-6 fatty acid desaturase \/ acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.6 1.14.19.22]"
			},
			{
				"name":"K10255  FAD6, desA; acyl-lipid omega-6 desaturase (Delta-12 desaturase) [EC:1.14.19.23 1.14.19.45]"
			},
			{
				"name":"K10257  FAD3, FAD7, FAD8, desB; acyl-lipid omega-3 desaturase [EC:1.14.19.25 1.14.19.35 1.14.19.36]"
			},
			{
				"name":"K10225  FADS3; fatty acid desaturase 3 (Delta-13 desaturase) [EC:1.14.19.-]"
			}
			]
		},
		{
			"name":"Front-end",
			"children":[
			{
				"name":"K00508  desD; sn-1 linoleoyl-lipid 6-desaturase [EC:1.14.19.46]"
			},
			{
				"name":"K10224  FADS1; acyl-CoA (8-3)-desaturase (Delta-5 desaturase) [EC:1.14.19.44]"
			},
			{
				"name":"K10226  FADS2; acyl-CoA 6-desaturase (Delta-6 desaturase) [EC:1.14.19.3]"
			},
			{
				"name":"K12418  DES4, des1; acyl-lipid (7-3)-desaturase (Delta-4 desaturase) [EC:1.14.19.31]"
			}
			]
		},
		{
			"name":"Sphingolipid",
			"children":[
			{
				"name":"K04712  DEGS; sphingolipid 4-desaturase\/C4-monooxygenase [EC:1.14.19.17 1.14.18.5]"
			}
			]
		},
		{
			"name":"Other",
			"children":[
			{
				"name":"K12419  FADS6; fatty acid desaturase 6 [EC:1.14.19.-]"
			}
			]
		}
		]
	},
	{
		"name":"Elongase",
		"children":[
		{
			"name":"LCFA",
			"children":[
			{
				"name":"K10245  ELO2; fatty acid elongase 2 [EC:2.3.1.199]"
			},
			{
				"name":"K10246  ELO3; fatty acid elongase 3 [EC:2.3.1.199]"
			}
			]
		},
		{
			"name":"PUFA",
			"children":[
			{
				"name":"K10247  ELOVL1; elongation of very long chain fatty acids protein 1 [EC:2.3.1.199]"
			},
			{
				"name":"K10205  ELOVL2; elongation of very long chain fatty acids protein 2 [EC:2.3.1.199]"
			},
			{
				"name":"K10249  ELOVL4; elongation of very long chain fatty acids protein 4 [EC:2.3.1.199]"
			},
			{
				"name":"K10244  ELOVL5; elongation of very long chain fatty acids protein 5 [EC:2.3.1.199]"
			},
			{
				"name":"K10203  ELOVL6; elongation of very long chain fatty acids protein 6 [EC:2.3.1.199]"
			},
			{
				"name":"K10250  ELOVL7; elongation of very long chain fatty acids protein 7 [EC:2.3.1.199]"
			}
			]
		},
		{
			"name":"Unclassified",
			"children":[
			{
				"name":"K10248  ELOVL3; elongation of very long chain fatty acids protein 3 [EC:2.3.1.199]"
			}
			]
		}
		]
	},
	{
		"name":"Polyketide synthase",
		"children":[
		{
			"name":"Modular PKS",
			"children":[
			{
				"name":"K10817  eryAI; 6-deoxyerythronolide-B synthase EryAI [EC:2.3.1.94]"
			},
			{
				"name":"K04786  irp1, HMWP1; yersiniabactin nonribosomal peptide\/polyketide synthase"
			},
			{
				"name":"K04784  irp2, HMWP2; yersiniabactin nonribosomal peptide synthetase"
			},
			{
				"name":"K11628  mas; mycocerosic acid synthase [EC:2.3.1.111]"
			},
			{
				"name":"K12430  pks1_15; 4-hydroxyphenylalkanoate synthase [EC:2.3.1.261]"
			},
			{
				"name":"K12431  pks2; phthioceranic\/hydroxyphthioceranic acid synthase [EC:2.3.1.287]"
			},
			{
				"name":"K12436  pks12; mycoketide-CoA synthase [EC:2.3.1.295]"
			},
			{
				"name":"K12437  pks13; polyketide synthase 13"
			},
			{
				"name":"K13611  pksJ, baeJ; bacillaene biosynthesis, polyketide synthase \/ nonribosomal peptide synthetase PksJ\/BaeJ"
			},
			{
				"name":"K13612  pksL, baeL; bacillaene polyketide synthase PksL\/BaeL"
			},
			{
				"name":"K13613  pksM, baeM; bacillaene polyketide synthase PksM\/BaeM"
			},
			{
				"name":"K13614  pksN, baeN; bacillaene biosynthesis, polyketide synthase \/ nonribosomal peptide synthetase PksN\/BaeN"
			},
			{
				"name":"K13615  pksR, baeR; bacillaene polyketide synthase PksR\/BaeR"
			},
			{
				"name":"K12440  ppsA; phthiocerol\/phenolphthiocerol synthesis type-I polyketide synthase A [EC:2.3.1.292]"
			},
			{
				"name":"K12441  ppsB; phthiocerol\/phenolphthiocerol synthesis type-I polyketide synthase B [EC:2.3.1.292]"
			},
			{
				"name":"K12442  ppsC; phthiocerol\/phenolphthiocerol synthesis type-I polyketide synthase C [EC:2.3.1.292]"
			},
			{
				"name":"K12443  ppsD; phthiocerol\/phenolphthiocerol synthesis type-I polyketide synthase D [EC:2.3.1.292]"
			},
			{
				"name":"K12444  ppsE; phthiocerol\/phenolphthiocerol synthesis type-I polyketide synthase E [EC:2.3.1.292]"
			}
			]
		},
		{
			"name":"Component type",
			"children":[
			{
				"name":"K05551  actI1, oxyA, tcmK, snoa1, aknB, mtmP; minimal PKS ketosynthase (KS\/KS alpha) [EC:2.3.1.- 2.3.1.260 2.3.1.235]"
			},
			{
				"name":"K05552  actI2, oxyB, tcmL, snoa2, aknC, mtmK; minimal PKS chain-length factor (CLF\/KS beta) [EC:2.3.1.- 2.3.1.260 2.3.1.235]"
			},
			{
				"name":"K05553  actI3, oxyC, tcmM, snoa3, aknD, mtmS; minimal PKS acyl carrier protein"
			},
			{
				"name":"K12420  actIII, oxyJ, snoaD, aknA; ketoreductase [EC:1.1.1.-]"
			},
			{
				"name":"K05554  actVII; aromatase [EC:4.2.1.-]"
			},
			{
				"name":"K04790  mbtC; mycobactin polyketide synthetase MbtC"
			},
			{
				"name":"K04791  mbtD; mycobactin polyketide synthetase MbtD"
			}
			]
		}
		]
	},
	{
		"name":"Acyl-CoA ligase",
		"children":[
		{
			"name":"Short\/medium chain acyl-CoA ligase",
			"children":[
			{
				"name":"K01895  ACSS1_2, acs; acetyl-CoA synthetase [EC:6.2.1.1]"
			},
			{
				"name":"K01908  ACSS3, prpE; propionyl-CoA synthetase [EC:6.2.1.17]"
			},
			{
				"name":"K01907  AACS, acsA; acetoacetyl-CoA synthetase [EC:6.2.1.16]"
			},
			{
				"name":"K23756  ACSM1, LAE; medium-chain acyl-CoA ligase \/ lipoate-activating enzyme [EC:6.2.1.2]"
			},
			{
				"name":"K01896  ACSM; medium-chain acyl-CoA synthetase [EC:6.2.1.2]"
			},
			{
				"name":"K23617  ACSF2; medium-chain acyl-CoA ligase, mitochondrial [EC:6.2.1.2]"
			},
			{
				"name":"K01913  AAE7, ACN1; acetate\/butyrate---CoA ligase [EC:6.2.1.1 6.2.1.2]"
			},
			{
				"name":"K23618  AAE11_12; acyl-activating enzyme 11\/12 [EC:6.2.1.2 6.2.1.-]"
			},
			{
				"name":"K01905  acdA; acetate---CoA ligase (ADP-forming) subunit alpha [EC:6.2.1.13]"
			},
			{
				"name":"K22224  acdB; acetate---CoA ligase (ADP-forming) subunit beta [EC:6.2.1.13]"
			},
			{
				"name":"K24012  acdAB; acetate---CoA ligase (ADP-forming) [EC:6.2.1.13]"
			},
			{
				"name":"K12507  fadK; acyl-CoA synthetase [EC:6.2.1.-]"
			},
			{
				"name":"K13776  atuH; citronellyl-CoA synthetase [EC:6.2.1.-]"
			}
			]
		},
		{
			"name":"Long\/very long chain acyl-CoA ligase",
			"children":[
			{
				"name":"K01897  ACSL, fadD; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"K15013  ACSBG; long-chain-fatty-acid---CoA ligase [EC:6.2.1.3]"
			},
			{
				"name":"K03822  K03822; putative long chain acyl-CoA synthase [EC:6.2.1.-]"
			},
			{
				"name":"K12429  fadD36; fatty acid CoA ligase FadD36"
			},
			{
				"name":"K08745  SLC27A1_4, FATP1_4; solute carrier family 27 (fatty acid transporter), member 1\/4 [EC:6.2.1.-]"
			},
			{
				"name":"K08746  SLC27A2, FACVL1, FATP2; solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3]"
			},
			{
				"name":"K08772  SLC27A3, FATP3; solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-]"
			}
			]
		},
		{
			"name":"Unknown",
			"children":[
			{
				"name":"K12421  fadD9; fatty acid CoA ligase FadD9"
			},
			{
				"name":"K12423  fadD21; fatty acid CoA ligase FadD21"
			},
			{
				"name":"K00142  AASDH; acyl-CoA synthetase [EC:6.2.1.-]"
			},
			{
				"name":"K00666  K00666; fatty-acyl-CoA synthase [EC:6.2.1.-]"
			}
			]
		}
		]
	},
	{
		"name":"Acyl-AMP ligase",
		"children":[
		{
			"name":"Fatty acyl-AMP ligase (FAAL)",
			"children":[
			{
				"name":"K12422  fadD10; medium\/long-chain-fatty-acid---[acyl-carrier-protein] ligase FadD10 [EC:6.2.1.-]"
			},
			{
				"name":"K12425  fadD23; long-chain fatty acid adenylase\/transferase FadD23 [EC:6.2.1.57]"
			},
			{
				"name":"K12426  fadD26; long-chain fatty acid adenylase\/transferase FadD26 [EC:6.2.1.59]"
			},
			{
				"name":"K12427  fadD28; long-chain fatty acid adenylyltransferase FadD28 [EC:6.2.1.49]"
			},
			{
				"name":"K21059  fadD29; 4-hydroxyphenylalkanoate adenylyltransferase [EC:6.2.1.51]"
			},
			{
				"name":"K12428  fadD32; fatty acyl-AMP ligase FadD32 [EC:6.2.1.-]"
			}
			]
		},
		{
			"name":"Aryl-AMP ligase",
			"children":[
			{
				"name":"K12424  fadD22; 4-hydroxybenzoate adenylyltransferase [EC:6.2.1.50]"
			}
			]
		}
		]
	},
	{
		"name":"Phospholipid acyltransferase",
		"children":[
		{
			"name":"GPAT",
			"children":[
			{
				"name":"K00629  GPAT1_2; glycerol-3-phosphate O-acyltransferase 1\/2 [EC:2.3.1.15]"
			},
			{
				"name":"K13506  GPAT3_4, AGPAT9, AGPAT6; glycerol-3-phosphate O-acyltransferase 3\/4 [EC:2.3.1.15]"
			},
			{
				"name":"K13507  GAT; glycerol-3-phosphate O-acyltransferase \/ dihydroxyacetone phosphate acyltransferase [EC:2.3.1.15 2.3.1.42]"
			},
			{
				"name":"K00630  ATS1; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]"
			},
			{
				"name":"K13508  GPAT; glycerol-3-phosphate acyltransferase [EC:2.3.1.15 2.3.1.198]"
			},
			{
				"name":"K00631  plsB; glycerol-3-phosphate O-acyltransferase [EC:2.3.1.15]"
			},
			{
				"name":"K03621  plsX; phosphate acyltransferase [EC:2.3.1.274]"
			},
			{
				"name":"K08591  plsY; acyl phosphate:glycerol-3-phosphate acyltransferase [EC:2.3.1.275]"
			}
			]
		},
		{
			"name":"LPAAT\/LPLAT",
			"children":[
			{
				"name":"K13509  AGPAT1_2; lysophosphatidate acyltransferase [EC:2.3.1.51]"
			},
			{
				"name":"K13699  ABHD5, CGI-58; abhydrolase domain-containing protein 5 [EC:2.3.1.51]"
			},
			{
				"name":"K13513  LCLAT1, AGPAT8; lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51]"
			},
			{
				"name":"K13511  TAZ; monolysocardiolipin acyltransferase [EC:2.3.1.-]"
			},
			{
				"name":"K13517  MBOAT1_2; lysophospholipid acyltransferase 1\/2 [EC:2.3.1.51 2.3.1.-]"
			},
			{
				"name":"K13519  LPT1, ALE1; lysophospholipid acyltransferase [EC:2.3.1.51 2.3.1.23 2.3.1.-]"
			},
			{
				"name":"K13523  AGPAT3_4; lysophosphatidic acid acyltransferase \/ lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-]"
			},
			{
				"name":"K00655  plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]"
			},
			{
				"name":"K13510  LPCAT1_2; lysophosphatidylcholine acyltransferase \/ lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67]"
			},
			{
				"name":"K13512  LPCAT4, AGPAT7; lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-]"
			},
			{
				"name":"K13514  LPGAT1; lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-]"
			},
			{
				"name":"K13515  LPCAT3, MBOAT5; lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-]"
			},
			{
				"name":"K13516  MBOAT7; lysophospholipid acyltransferase 7 [EC:2.3.1.-]"
			}
			]
		}
		]
	},
	{
		"name":"Others",
		"children":[
		{
			"name":"Multifunctional type",
			"children":[
			{
				"name":"K12432  pks3_4; mycolipanoate synthase [EC:2.3.1.252]"
			},
			{
				"name":"K12433  pks5; polyketide synthase 5"
			},
			{
				"name":"K12434  pks7; polyketide synthase 7"
			},
			{
				"name":"K12435  pks8; polyketide synthase 8"
			},
			{
				"name":"K12439  pks17; polyketide synthase 17"
			}
			]
		},
		{
			"name":"Component type",
			"children":[
			{
				"name":"K12445  K12445; trans enoyl reductase [EC:1.3.1.-]"
			}
			]
		}
		]
	}
	]
}