{
	"name":"ko03016",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"K01164  POP1; ribonuclease P\/MRP protein subunit POP1 [EC:3.1.26.5]"
				},
				{
					"name":"K14522  POP3; ribonuclease P\/MRP protein subunit POP3 [EC:3.1.26.5]"
				},
				{
					"name":"K03538  POP4, RPP29; ribonuclease P protein subunit POP4 [EC:3.1.26.5]"
				},
				{
					"name":"K03537  POP5; ribonuclease P\/MRP protein subunit POP5 [EC:3.1.26.5]"
				},
				{
					"name":"K14524  POP6; ribonuclease P\/MRP protein subunit POP6 [EC:3.1.26.5]"
				},
				{
					"name":"K14526  POP7, RPP2; ribonuclease P\/MRP protein subunit POP7 [EC:3.1.26.5]"
				},
				{
					"name":"K14528  POP8; ribonuclease P\/MRP protein subunit POP8 [EC:3.1.26.5]"
				},
				{
					"name":"K03539  RPP1, RPP30; ribonuclease P\/MRP protein subunit RPP1 [EC:3.1.26.5]"
				},
				{
					"name":"K03540  RPR2, RPP21; ribonuclease P protein subunit RPR2 [EC:3.1.26.5]"
				},
				{
					"name":"K14529  RPP14; ribonuclease P protein subunit RPP14 [EC:3.1.26.5]"
				},
				{
					"name":"K14527  RPP20, POP7; ribonuclease P\/MRP protein subunit RPP20 [EC:3.1.26.5]"
				},
				{
					"name":"K14525  RPP25; ribonucleases P\/MRP protein subunit RPP25 [EC:3.1.26.5]"
				},
				{
					"name":"K14523  RPP38; ribonucleases P\/MRP protein subunit RPP38 [EC:3.1.26.5]"
				},
				{
					"name":"K14530  RPP40; ribonucleases P\/MRP protein subunit RPP40 [EC:3.1.26.5]"
				},
				{
					"name":"K18213  PRORP; proteinaceous RNase P [EC:3.1.26.5]"
				},
				{
					"name":"K14533  RPM2; ribonuclease P protein component, mitochondrial [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"K00784  rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"K01166  RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				},
				{
					"name":"K01167  rnaSA; ribonuclease T1 [EC:4.6.1.24]"
				},
				{
					"name":"K17710  PTCD1; pentatricopeptide repeat domain-containing protein 1"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"K00974  cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonuclease complex",
				"children":[
				{
					"name":"K15322  TSEN2; tRNA-splicing endonuclease subunit Sen2 [EC:4.6.1.16]"
				},
				{
					"name":"K15323  TSEN34; tRNA-splicing endonuclease subunit Sen34 [EC:4.6.1.16]"
				},
				{
					"name":"K15324  TSEN15; tRNA-splicing endonuclease subunit Sen15"
				},
				{
					"name":"K15325  SEN15; tRNA-splicing endonuclease subunit Sen15, fungi type"
				},
				{
					"name":"K15326  TSEN54; tRNA-splicing endonuclease subunit Sen54"
				}
				]
			},
			{
				"name":"tRNA splicing ligase complex",
				"children":[
				{
					"name":"K14415  RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				},
				{
					"name":"K15432  ASW; ashwin"
				},
				{
					"name":"K15433  CGI99, CLE7, RLLM1; RLL motif containing protein 1"
				},
				{
					"name":"K15434  FAM98B; protein FAM98B"
				},
				{
					"name":"K13177  DDX1; ATP-dependent RNA helicase DDX1 [EC:5.6.2.7]"
				},
				{
					"name":"K24956  ZBTB8OS; protein archease"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors",
				"children":[
				{
					"name":"K10669  TRPT1, TPT1; 2'-phosphotransferase [EC:2.7.1.160]"
				},
				{
					"name":"K20000  MATK; maturase K"
				},
				{
					"name":"K15435  CPD1; 2',3'-cyclic-nucleotide 3'-phosphodiesterase [EC:3.1.4.37]"
				},
				{
					"name":"K14679  TRL1; tRNA ligase [EC:6.5.1.3]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"K07936  RAN; GTP-binding nuclear protein Ran"
				},
				{
					"name":"K14288  XPOT; exportin-T"
				},
				{
					"name":"K14290  XPO1, CRM1; exportin-1"
				},
				{
					"name":"K14289  XPO5; exportin-5"
				},
				{
					"name":"K03231  EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"K14547  UTP8; U3 small nucleolar RNA-associated protein 8"
				},
				{
					"name":"K08876  SCYL1; SCY1-like protein 1"
				},
				{
					"name":"K24887  GTPBP1; GTP-binding protein 1"
				}
				]
			},
			{
				"name":"tRNA import factors",
				"children":[
				{
					"name":"K15436  TRPO3, MTR10; transportin-3"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"K14163  EPRS; bifunctional glutamyl\/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]"
				},
				{
					"name":"K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"K01881  PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				},
				{
					"name":"K01870  IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"K01869  LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"K01874  MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"K01886  QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"K01887  RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"K04567  KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"K22503  DARS1; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"K01876  DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"K15437  AIMP1, ARC1; aminoacyl tRNA synthase complex-interacting multifunctional protein 1"
				},
				{
					"name":"K15438  AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2"
				},
				{
					"name":"K15439  EEF1E1, AIMP3; eukaryotic translation elongation factor 1 epsilon-1"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"K01872  AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"K01893  NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"K01880  GARS, glyS1; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"K01868  TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"K01875  SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"K01883  CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"K01873  VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"K01892  HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"K01889  FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"K01890  FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"K01866  YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"K01867  WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"K07560  dtd, DTD; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"K09716  dtdA, GEK1; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"K07050  AARSD1, ALAX; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]"
				}
				]
			},
			{
				"name":"AARS associated factors",
				"children":[
				{
					"name":"K24278  ERDS; ergosteryl-3beta-O-L-aspartate synthase [EC:6.1.1.12 2.3.2.37]"
				},
				{
					"name":"K24279  ERDH; ergosteryl-3beta-O-L-aspartate hydrolase [EC:3.1.1.121]"
				},
				{
					"name":"K25102  TRNAU1AP; tRNA selenocysteine 1-associated protein 1"
				},
				{
					"name":"K02503  HINT1_2, hinT, hit; histidine triad (HIT) family protein [EC:3.9.1.-]"
				},
				{
					"name":"K12150  HINT3; adenosine 5'-monophosphoramidase HINT3 [EC:3.9.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"K15440  TAD1, ADAT1; tRNA-specific adenosine deaminase 1 [EC:3.5.4.34]"
				},
				{
					"name":"K15441  TAD2, ADAT2; tRNA-specific adenosine deaminase 2 [EC:3.5.4.-]"
				},
				{
					"name":"K15442  TAD3, ADAT3; tRNA-specific adenosine deaminase 3"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"K05542  DUS1; tRNA-dihydrouridine synthase 1 [EC:1.3.1.88]"
				},
				{
					"name":"K05543  DUS2; tRNA-dihydrouridine synthase 2 [EC:1.3.1.91]"
				},
				{
					"name":"K05544  DUS3; tRNA-dihydrouridine synthase 3 [EC:1.3.1.89]"
				},
				{
					"name":"K05545  DUS4; tRNA-dihydrouridine synthase 4 [EC:1.3.1.90]"
				}
				]
			},
			{
				"name":"Methylthiotransferase",
				"children":[
				{
					"name":"K06168  CDK5RAP1, miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"K15865  CDKAL1, mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"K00555  TRMT1, trm1; tRNA (guanine26-N2\/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216]"
				},
				{
					"name":"K15332  TRMT2A; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K15331  TRMT2B, TRM2; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]"
				},
				{
					"name":"K15333  TRM3, TARBP1; tRNA guanosine-2'-O-methyltransferase [EC:2.1.1.34]"
				},
				{
					"name":"K15334  NCL1, TRM4; multisite-specific tRNA:(cytosine-C5)-methyltransferase [EC:2.1.1.202]"
				},
				{
					"name":"K15335  NSUN2, TRM4; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203]"
				},
				{
					"name":"K21969  NSUN3; tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K21971  NSUN6; methyltransferase NSUN6 [EC:2.1.1.-]"
				},
				{
					"name":"K15429  TRM5, TRMT5; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"K07442  TRM61, GCD14; tRNA (adenine57-N1\/adenine58-N1)-methyltransferase catalytic subunit [EC:2.1.1.219 2.1.1.220]"
				},
				{
					"name":"K03256  TRM6, GCD10; tRNA (adenine58-N1)-methyltransferase non-catalytic subunit"
				},
				{
					"name":"K14864  FTSJ1, TRM7; tRNA (cytidine32\/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205]"
				},
				{
					"name":"K03439  trmB, METTL1, TRM8; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"K24974  METTL2; tRNA N(3)-methylcytidine methyltransferase METTL2 [EC:2.1.1.-]"
				},
				{
					"name":"K00599  METTL6; tRNA N(3)-methylcytidine methyltransferase METTL6 [EC:2.1.1.-]"
				},
				{
					"name":"K15444  TRM9; tRNA (uracil-5-)-methyltransferase TRM9 [EC:2.1.1.229]"
				},
				{
					"name":"K10770  ALKBH8, TRM9; alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229]"
				},
				{
					"name":"K28867  TRMT9B; tRNA methyltransferase 9B [EC:2.1.1.-]"
				},
				{
					"name":"K15445  TRMT10, TRM10, RG9MTD; tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221]"
				},
				{
					"name":"K15430  TRM11, TRMT11; tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214]"
				},
				{
					"name":"K15446  TRM13, CCDC76; tRNA:m4X modification enzyme [EC:2.1.1.225]"
				},
				{
					"name":"K15447  TRM44, METTL19; tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211]"
				},
				{
					"name":"K15443  TRM82, WDR4; tRNA (guanine-N(7)-)-methyltransferase subunit TRM82"
				},
				{
					"name":"K28362  THUMPD3; tRNA (guanine(6\/7)-N(2))-methyltransferase [EC:2.1.1.256 2.1.1.-]"
				},
				{
					"name":"K15448  TRM112, TRMT112; multifunctional methyltransferase subunit TRM112"
				},
				{
					"name":"K15336  TRDMT1, DNMT2; tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204]"
				},
				{
					"name":"K22900  TRMO, trmO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K17053  ABP140; tRNAThr (cytosine32-N3)-methyltransferase [EC:2.1.1.268]"
				},
				{
					"name":"K15449  TYW1; tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44]"
				},
				{
					"name":"K07055  TRM12, TYW2; tRNA wybutosine-synthesizing protein 2 [EC:2.5.1.114]"
				},
				{
					"name":"K15450  TYW3; tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282]"
				},
				{
					"name":"K15451  PPM2, LCMT2, TYW4; tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231]"
				},
				{
					"name":"K18066  TYW5; tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42]"
				},
				{
					"name":"K25191  BCDIN3D; RNA 5'-monophosphate methyltransferase [EC:2.1.1.-]"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"K06173  truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"K15452  PUS2; mitochondrial tRNA pseudouridine27\/28 synthase [EC:5.4.99.44]"
				},
				{
					"name":"K01855  PUS3, DEG1; tRNA pseudouridine38\/39 synthase [EC:5.4.99.45]"
				},
				{
					"name":"K03177  truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"K15453  PUS6; tRNA pseudouridine31 synthase [EC:5.4.99.42]"
				},
				{
					"name":"K06176  truD, PUS7; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				},
				{
					"name":"K14655  RIB2, PUS8; tRNA pseudouridine32 synthase \/ 2,5-diamino-6-(5-phospho-D-ribitylamino)-pyrimidin-4(3H)-one deaminase [EC:5.4.99.28]"
				},
				{
					"name":"K15454  PUS9; tRNA pseudouridine32 synthase [EC:5.4.99.28]"
				},
				{
					"name":"K07583  PUS10; tRNA pseudouridine synthase 10 [EC:5.4.99.25]"
				},
				{
					"name":"K22538  RPUSD4; mitochondrial RNA pseudouridine synthase RPUSD4 [EC:5.4.99.-]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"K21027  TRMU, SLM3; tRNA-5-taurinomethyluridine 2-sulfurtransferase [EC:2.8.1.14]"
				},
				{
					"name":"K14168  CTU1, NCS6; cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-]"
				},
				{
					"name":"K14169  CTU2, NCS2; cytoplasmic tRNA 2-thiolation protein 2"
				},
				{
					"name":"K04487  iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"K12161  URM1; ubiquitin related modifier 1"
				},
				{
					"name":"K11996  MOCS3, UBA4; adenylyltransferase and sulfurtransferase [EC:2.7.7.80 2.8.1.11]"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"K08851  TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"K01409  OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				},
				{
					"name":"K15901  TPRKB, CGI121; EKC\/KEOPS complex subunit TPRKB\/CGI121"
				},
				{
					"name":"K15902  LAGE3, PCC1; EKC\/KEOPS complex subunit LAGE3\/PCC1"
				},
				{
					"name":"K15903  GON7, PCC2; EKC\/KEOPS complex subunit GON7"
				}
				]
			},
			{
				"name":"Elongator complex",
				"children":[
				{
					"name":"K11373  ELP1, IKI3, IKBKAP; elongator complex protein 1"
				},
				{
					"name":"K11374  ELP2; elongator complex protein 2"
				},
				{
					"name":"K07739  ELP3, KAT9; elongator complex protein 3 (tRNA carboxymethyluridine synthase) [EC:2.3.1.311]"
				},
				{
					"name":"K11375  ELP4; elongator complex protein 4"
				},
				{
					"name":"K11376  ELP5, IKI1; elongator complex protein 5"
				},
				{
					"name":"K11377  ELP6; elongator complex protein 6"
				}
				]
			},
			{
				"name":"Elongator related proteins",
				"children":[
				{
					"name":"K15455  DPH3, KTI11; diphthamide biosynthesis protein 3"
				},
				{
					"name":"K15456  KTI12; protein KTI12"
				},
				{
					"name":"K15462  KTI13, ATS1; protein ATS1"
				},
				{
					"name":"K14758  HRR25; casein kinase I homolog HRR25 [EC:2.7.11.1]"
				},
				{
					"name":"K15427  SIT4, PPH1; serine\/threonine-protein phosphatase PP1-1 [EC:3.1.3.16]"
				},
				{
					"name":"K15457  SAP155; SIT4-associating protein SAP155"
				},
				{
					"name":"K15458  SAP185_190; SIT4-associating protein SAP185\/190"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"K07566  tsaC, rimN, SUA5, YRDC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"K00791  miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"K03650  mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"K03495  gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"K00777  QTRT1; queuine tRNA-ribosyltransferase catalytic subunit [EC:2.4.2.64]"
				},
				{
					"name":"K15407  QTRT2, QTRTD1; queuine tRNA-ribosyltransferase accessory subunit"
				},
				{
					"name":"K15463  RIT1; tRNA A64-2'-O-ribosylphosphate transferase [EC:2.4.2.-]"
				},
				{
					"name":"K01008  selD, SEPHS; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"K06963  TAN1, THUMPD1; tRNA acetyltransferase TAN1"
				},
				{
					"name":"K10761  THG1; tRNA(His) guanylyltransferase [EC:2.7.7.79]"
				},
				{
					"name":"K00685  ATE1; arginyl-tRNA---protein transferase [EC:2.3.2.8]"
				},
				{
					"name":"K24973  DALRD3; DALR anticodon-binding domain-containing protein 3"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"TRAMP complex",
				"children":[
				{
					"name":"K03514  PAPD5_7, TRF4; non-canonical poly(A) RNA polymerase PAPD5\/7 [EC:2.7.7.19]"
				},
				{
					"name":"K12597  AIR1_2; protein AIR1\/2"
				},
				{
					"name":"K12598  MTR4, SKIV2L2; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]"
				}
				]
			},
			{
				"name":"Rapid tRNA decay (RTD) pathway factors",
				"children":[
				{
					"name":"K12618  XRN1, SEP1, KEM1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]"
				},
				{
					"name":"K12619  XRN2, RAT1; 5'-3' exoribonuclease 2 [EC:3.1.13.-]"
				},
				{
					"name":"K01082  cysQ, MET22, BPNT1; 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7]"
				}
				]
			},
			{
				"name":"Other tRNA degradation factors",
				"children":[
				{
					"name":"K16631  ANG, RNASE5; angiogenin [EC:3.1.27.-]"
				},
				{
					"name":"K24459  SLFN13; schlafen family member 13 [EC:3.1.-.-]"
				},
				{
					"name":"K24850  IFIT5; interferon-induced protein with tetratricopeptide repeats 5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"5'processing factors",
			"children":[
			{
				"name":"Ribonucrease P",
				"children":[
				{
					"name":"K03536  rnpA; ribonuclease P protein component [EC:3.1.26.5]"
				},
				{
					"name":"K01978  rnpB; RNase P catalytic RNA component"
				},
				{
					"name":"K09006  K09006; RNA-free ribonuclease P [EC:3.1.26.5]"
				}
				]
			}
			]
		},
		{
			"name":"3'processing and CCA adding factors",
			"children":[
			{
				"name":"3'processing factors",
				"children":[
				{
					"name":"K00784  rnz; ribonuclease Z [EC:3.1.26.11]"
				},
				{
					"name":"K03683  rnt; ribonuclease T [EC:3.1.13.-]"
				},
				{
					"name":"K00989  rph; ribonuclease PH [EC:2.7.7.56]"
				},
				{
					"name":"K01169  rna; ribonuclease I (enterobacter ribonuclease) [EC:4.6.1.21]"
				},
				{
					"name":"K01147  rnb; exoribonuclease II [EC:3.1.13.1]"
				},
				{
					"name":"K03684  rnd; ribonuclease D [EC:3.1.13.5]"
				},
				{
					"name":"K01166  RNASET2; ribonuclease T2 [EC:4.6.1.19]"
				},
				{
					"name":"K01167  rnaSA; ribonuclease T1 [EC:4.6.1.24]"
				}
				]
			},
			{
				"name":"CCA adding factors",
				"children":[
				{
					"name":"K00974  cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]"
				},
				{
					"name":"K07558  K07558, cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA spricing factors",
			"children":[
			{
				"name":"tRNA splicing endonucleases",
				"children":[
				{
					"name":"K01170  endA; tRNA-intron endonuclease, archaea type [EC:4.6.1.16]"
				}
				]
			},
			{
				"name":"tRNA splicing ligases",
				"children":[
				{
					"name":"K14415  RTCB, rtcB; tRNA-splicing ligase RtcB (3'-phosphate\/5'-hydroxy nucleic acid ligase) [EC:6.5.1.8]"
				}
				]
			},
			{
				"name":"Other tRNA splicing factors",
				"children":[
				{
					"name":"K01975 thpR; RNA 2',3'-cyclic 3'-phosphodiesterase [EC:3.1.4.58]"
				},
				{
					"name":"K07559  kptA; putative RNA 2'-phosphotransferase [EC:2.7.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA transport factors",
			"children":[
			{
				"name":"tRNA export factors",
				"children":[
				{
					"name":"K06020  ettA; energy-dependent translational throttle protein EttA"
				}
				]
			}
			]
		},
		{
			"name":"Aminoacyl-tRNA synthetases (AARSs)",
			"children":[
			{
				"name":"Multi-aminoacyl-tRNA synthetase complex (MSC)",
				"children":[
				{
					"name":"K01869  LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]"
				},
				{
					"name":"K04566  lysK; lysyl-tRNA synthetase, class I [EC:6.1.1.6]"
				},
				{
					"name":"K01881  PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]"
				}
				]
			},
			{
				"name":"Other AARSs",
				"children":[
				{
					"name":"K01866  YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]"
				},
				{
					"name":"K01867  WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]"
				},
				{
					"name":"K01868  TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]"
				},
				{
					"name":"K01870  IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]"
				},
				{
					"name":"K04567  KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]"
				},
				{
					"name":"K01872  AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]"
				},
				{
					"name":"K01873  VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]"
				},
				{
					"name":"K01874  MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]"
				},
				{
					"name":"K01875  SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]"
				},
				{
					"name":"K01876  DARS2, aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]"
				},
				{
					"name":"K01878  glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]"
				},
				{
					"name":"K01879  glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]"
				},
				{
					"name":"K14164  glyQS; glycyl-tRNA synthetase [EC:6.1.1.14]"
				},
				{
					"name":"K01883  CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]"
				},
				{
					"name":"K01884  cysS1; cysteinyl-tRNA synthetase, unknown class [EC:6.1.1.16]"
				},
				{
					"name":"K01885  EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]"
				},
				{
					"name":"K01886  QARS, glnS; glutaminyl-tRNA synthetase [EC:6.1.1.18]"
				},
				{
					"name":"K01887  RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]"
				},
				{
					"name":"K01889  FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]"
				},
				{
					"name":"K01890  FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]"
				},
				{
					"name":"K01892  HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]"
				},
				{
					"name":"K01893  NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]"
				},
				{
					"name":"K01894  gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]"
				},
				{
					"name":"K09759  aspC, aspS; nondiscriminating aspartyl-tRNA synthetase [EC:6.1.1.23]"
				},
				{
					"name":"K09698  gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]"
				},
				{
					"name":"K11627  pylS; pyrrolysyl-tRNA synthetase [EC:6.1.1.26]"
				},
				{
					"name":"K07587  sepRS; O-phosphoseryl-tRNA synthetase [EC:6.1.1.27]"
				},
				{
					"name":"K06868  sepcysS; Sep-tRNA:Cys-tRNA synthetase [EC:2.5.1.73]"
				}
				]
			},
			{
				"name":"Trans-editing factors",
				"children":[
				{
					"name":"K07560  dtd, DTD; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"K09716  dtdA, GEK1; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"K29064  dtd3; D-aminoacyl-tRNA deacylase [EC:3.1.1.96]"
				},
				{
					"name":"K03976  ybaK, ebsC; Cys-tRNA(Pro)\/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]"
				},
				{
					"name":"K19055  prdX, proX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]"
				},
				{
					"name":"K07050  AARSD1, ALAX; misacylated tRNA(Ala) deacylase [EC:3.1.1.-]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA modification factors",
			"children":[
			{
				"name":"Deaminases",
				"children":[
				{
					"name":"K11991  tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]"
				},
				{
					"name":"K16930  cdat8; tRNA(cytosine8) deaminase [EC:3.5.4.35]"
				}
				]
			},
			{
				"name":"Dihydorouridine synthases",
				"children":[
				{
					"name":"K05539  dusA; tRNA-dihydrouridine synthase A [EC:1.-.-.-]"
				},
				{
					"name":"K05540  dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]"
				},
				{
					"name":"K05541  dusC; tRNA-dihydrouridine synthase C [EC:1.-.-.-]"
				}
				]
			},
			{
				"name":"Methylthiotransferases",
				"children":[
				{
					"name":"K06168  CDK5RAP1, miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]"
				},
				{
					"name":"K15865  CDKAL1, mtaB; threonylcarbamoyladenosine tRNA methylthiotransferase [EC:2.8.4.5]"
				}
				]
			},
			{
				"name":"Methyltransferases",
				"children":[
				{
					"name":"K15256  cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K15257  cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K06219  smtA, cmoM; tRNA 5-carboxymethoxyuridine methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K02533  lasT; tRNA\/rRNA methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K04094  trmFO, gid; methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]"
				},
				{
					"name":"K00557  trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]"
				},
				{
					"name":"K03439  trmB, METTL1, TRM8; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]"
				},
				{
					"name":"K00554  trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]"
				},
				{
					"name":"K03650  mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]"
				},
				{
					"name":"K03214  yfiF, trmG; RNA methyltransferase, TrmH family [EC:2.1.1.-]"
				},
				{
					"name":"K00556  trmH; tRNA (guanosine-2'-O-)-methyltransferase [EC:2.1.1.34]"
				},
				{
					"name":"K15396  trmJ; tRNA (cytidine32\/uridine32-2'-O)-methyltransferase [EC:2.1.1.200]"
				},
				{
					"name":"K06967  trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]"
				},
				{
					"name":"K03216  trmL, cspR; tRNA (cytidine\/uridine-2'-O-)-methyltransferase [EC:2.1.1.207]"
				},
				{
					"name":"K22900  TRMO, trmO; tRNA (adenine37-N6)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K15460  yfiC, trmX; tRNA1Val (adenine37-N6)-methyltransferase [EC:2.1.1.223]"
				},
				{
					"name":"K16317  trmY; tRNA (pseudouridine54-N1)-methyltransferase [EC:2.1.1.257]"
				},
				{
					"name":"K22901  trm4; tRNA (cytosine40_48-C5)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K15566  trm10; tRNA (adenine9-N1\/guanine9-N1)-methyltransferase [EC:2.1.1.218 2.1.1.221]"
				},
				{
					"name":"K16318  trm14; tRNA (guanine6-N2)-methyltransferase [EC:2.1.1.256]"
				},
				{
					"name":"K07446  trm-G10; tRNA (guanine10-N2)-dimethyltransferase [EC:2.1.1.213]"
				},
				{
					"name":"K07254  atrm56; tRNA (cytidine56-2'-O)-methyltransferase [EC:2.1.1.206]"
				},
				{
					"name":"K22446  K22446; tRNA (cytosine49-C5)-methyltransferase [EC:2.1.1.-]"
				},
				{
					"name":"K03437  spoU; RNA methyltransferase, TrmH family"
				}
				]
			},
			{
				"name":"Psudouridine synthases",
				"children":[
				{
					"name":"K06173  truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]"
				},
				{
					"name":"K03177  truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]"
				},
				{
					"name":"K06175  truC; tRNA pseudouridine65 synthase [EC:5.4.99.26]"
				},
				{
					"name":"K06176  truD, PUS7; tRNA pseudouridine13 synthase [EC:5.4.99.27]"
				},
				{
					"name":"K06177  rluA; tRNA pseudouridine32 synthase \/ 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]"
				}
				]
			},
			{
				"name":"Thiolation factors",
				"children":[
				{
					"name":"K00566  mnmA, trmU; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]"
				},
				{
					"name":"K21947  ttuA; tRNA-5-methyluridine54 2-sulfurtransferase [EC:2.8.1.15]"
				},
				{
					"name":"K14058  ttcA; tRNA 2-thiocytidine biosynthesis protein TtcA"
				},
				{
					"name":"K04085  tusA, sirA; tRNA 2-thiouridine synthesizing protein A [EC:2.8.1.-]"
				},
				{
					"name":"K07237  tusB, dsrH; tRNA 2-thiouridine synthesizing protein B"
				},
				{
					"name":"K07236  tusC, dsrF; tRNA 2-thiouridine synthesizing protein C"
				},
				{
					"name":"K07235  tusD, dsrE; tRNA 2-thiouridine synthesizing protein D [EC:2.8.1.-]"
				},
				{
					"name":"K11179  tusE, dsrC; tRNA 2-thiouridine synthesizing protein E [EC:2.8.1.-]"
				},
				{
					"name":"K13628  iscA; iron-sulfur cluster assembly protein"
				},
				{
					"name":"K04487  iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]"
				},
				{
					"name":"K06980  ygfZ; tRNA-modifying protein YgfZ"
				}
				]
			},
			{
				"name":"KEOPS\/EKC complex",
				"children":[
				{
					"name":"K08851  TP53RK, PRPK, BUD32; TP53 regulating kinase and related kinases [EC:2.7.11.1]"
				},
				{
					"name":"K15904  kae1-bud32; bifunctional N6-L-threonylcarbamoyladenine synthase \/ protein kinase Bud32 [EC:2.3.1.234 2.7.11.1]"
				},
				{
					"name":"K01409  OSGEP, KAE1, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]"
				},
				{
					"name":"K09119  cgi121; KEOPS complex subunit Cgi121"
				},
				{
					"name":"K09741  pcc1; KEOPS complex subunit Pcc1"
				}
				]
			},
			{
				"name":"Other tRNA modification factors",
				"children":[
				{
					"name":"K03495  gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme"
				},
				{
					"name":"K00791  miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]"
				},
				{
					"name":"K06169  miaE; tRNA 2-(methylsulfanyl)-N6-isopentenyladenosine37 hydroxylase [EC:1.14.99.69]"
				},
				{
					"name":"K15461  mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]"
				},
				{
					"name":"K07568  queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]"
				},
				{
					"name":"K06920  queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]"
				},
				{
					"name":"K01737  queD, ptpS, PTS; 6-pyruvoyltetrahydropterin\/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]"
				},
				{
					"name":"K10026  queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]"
				},
				{
					"name":"K06879  queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]"
				},
				{
					"name":"K09457  queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]"
				},
				{
					"name":"K18979  queG; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"K09765  queH; epoxyqueuosine reductase [EC:1.17.99.6]"
				},
				{
					"name":"K01008  selD, SEPHS; selenide, water dikinase [EC:2.7.9.3]"
				},
				{
					"name":"K06917  selU, mnmH; tRNA 2-selenouridine synthase [EC:2.9.1.3]"
				},
				{
					"name":"K00773  tgt; queuine tRNA-ribosyltransferase [EC:2.4.2.29]"
				},
				{
					"name":"K18779  tgtA; 7-cyano-7-deazaguanine tRNA-ribosyltransferase [EC:2.4.2.48]"
				},
				{
					"name":"K03151  thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]"
				},
				{
					"name":"K06932  tiaS; tRNA(Ile2)-agmatinylcytidine synthase [EC:6.3.4.22]"
				},
				{
					"name":"K04075  tilS, mesJ; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]"
				},
				{
					"name":"K15780  tilS-hprT; bifunctional protein TilS\/HprT [EC:6.3.4.19 2.4.2.8]"
				},
				{
					"name":"K06957  tmcA; tRNA(Met) cytidine acetyltransferase [EC:2.3.1.193]"
				},
				{
					"name":"K14742  tsaB; tRNA threonylcarbamoyladenosine biosynthesis protein TsaB"
				},
				{
					"name":"K07566  tsaC, rimN, SUA5, YRDC; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]"
				},
				{
					"name":"K25706  tsaD; tRNA N6-adenosine threonylcarbamoyltransferase [EC:2.3.1.234]"
				},
				{
					"name":"K06925  tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE"
				},
				{
					"name":"K22132  tcdA; tRNA threonylcarbamoyladenosine dehydratase"
				},
				{
					"name":"K27343  tmcAL; tRNAmet cytidine acetate ligase [EC:6.3.1.22]"
				}
				]
			}
			]
		},
		{
			"name":"tRNA degradation factors",
			"children":[
			{
				"name":"K12573  rnr, vacB; ribonuclease R [EC:3.1.13.1]"
			},
			{
				"name":"K00962  pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]"
			},
			{
				"name":"K12579  ISG20; interferon-stimulated gene 20 kDa protein [EC:3.1.13.1]"
			},
			{
				"name":"K18828  mvpA, vapC; tRNA(fMet)-specific endonuclease VapC [EC:3.1.-.-]"
			}
			]
		}
		]
	}
	]
}