{
	"name":"ko03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"K02603  ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"K02604  ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"K02605  ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"K02606  ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"K02607  ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"K02608  ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"K10727  CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"K02213  CDC6; cell division control protein 6"
				},
				{
					"name":"K02540  MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"K02541  MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"K02212  MCM4, CDC54; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"K02209  MCM5, CDC46; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"K02542  MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"K02210  MCM7, CDC47; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"K06627  CCNA; cyclin-A"
				},
				{
					"name":"K06626  CCNE; G1\/S-specific cyclin-E1"
				},
				{
					"name":"K02206  CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"K02214  CDC7; cell division control protein 7 [EC:2.7.11.1]"
				},
				{
					"name":"K06629  DBF4, ASK; protein DBF4"
				},
				{
					"name":"K02309  DBF4; regulatory subunit for Cdc7p protein kinase"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"K10732  GINS1, PSF1; GINS complex subunit 1"
				},
				{
					"name":"K10733  GINS2, PSF2; GINS complex subunit 2"
				},
				{
					"name":"K10734  GINS3; GINS complex subunit 3"
				},
				{
					"name":"K10735  GINS4, SLD5; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"K03507  DPB11; DNA replication regulator DPB11"
				},
				{
					"name":"K10728  TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"K10729  SLD2; DNA replication regulator SLD2"
				},
				{
					"name":"K10730  RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"K10731  SLD3; DNA replication regulator SLD3"
				},
				{
					"name":"K06628  CDC45; cell division control protein 45"
				},
				{
					"name":"K10737  MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"K10738  MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"K10736  MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"K28390  MCMBP; minichromosome maintenance complex-binding protein"
				},
				{
					"name":"K15254  HELB; DNA helicase B [EC:5.6.2.3]"
				},
				{
					"name":"K24274  FAM111A; protein FAM111A"
				},
				{
					"name":"K26052  CINP; cyclin-dependent kinase 2-interacting protein"
				},
				{
					"name":"K26116  MTBP; Mdm2-binding protein"
				},
				{
					"name":"K26117  TICRR; Treslin"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"K02320  POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"K02321  POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"K02684  PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"K02685  PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"K02324  POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"K02325  POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"K02326  POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				},
				{
					"name":"K03506  POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"K02327  POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"K02328  POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"K03504  POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"K03505  POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)",
				"children":[
				{
					"name":"K02332  POLG; DNA polymerase gamma 1 [EC:2.7.7.7]"
				},
				{
					"name":"K02333  POLG2; DNA polymerase gamma 2"
				}
				]
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"K07466  RFA1, RPA1, rpa; replication factor A1"
				},
				{
					"name":"K10739  RFA2, RPA2; replication factor A2"
				},
				{
					"name":"K10740  RPA3; replication factor A3"
				},
				{
					"name":"K10741  RPA4; replication factor A4"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"K10754  RFC1; replication factor C subunit 1"
				},
				{
					"name":"K10755  RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"K10756  RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"K03469  rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]"
				},
				{
					"name":"K10743  RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"K10744  RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"K10745  RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"K04802  PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"K28763  PCLAF; PCNA-associated factor"
				},
				{
					"name":"K10742  DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"K19783  HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]"
				},
				{
					"name":"K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"K10746  EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"K25861  ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"K26118  ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"K00558  DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"K17398  DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				},
				{
					"name":"K17399  DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"K10749  GMNN; geminin"
				},
				{
					"name":"K26119  MCIDAS; multicilin"
				},
				{
					"name":"K05868  CCNB1; G2\/mitotic-specific cyclin-B1"
				},
				{
					"name":"K21770  CCNB2; G2\/mitotic-specific cyclin-B2"
				},
				{
					"name":"K21771  CCNB3; G2\/mitotic-specific cyclin-B3"
				},
				{
					"name":"K21777  CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"K02087  CDK1, CDC2; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex",
					"children":[
					{
						"name":"K11109  POT1; protection of telomeres protein 1"
					},
					{
						"name":"K11110  TERF1, TRF1; telomeric repeat-binding factor 1"
					},
					{
						"name":"K11111  TERF2, TRF2; telomeric repeat-binding factor 2"
					},
					{
						"name":"K11112  TINF2, TIN2; TERF1-interacting nuclear factor 2"
					},
					{
						"name":"K11113  TERF2IP, RAP1; telomeric repeat-binding factor 2-interacting protein 1"
					},
					{
						"name":"K11114  ACD, TPP1; adrenocortical dysplasia protein"
					}
					]
				},
				{
					"name":"TERB1-TERB2-MAJIN complex",
					"children":[
					{
						"name":"K25749  TERB1; telomere repeats-binding bouquet formation protein 1"
					},
					{
						"name":"K25750  TERB2; telomere repeats-binding bouquet formation protein 2"
					},
					{
						"name":"K25751  MAJIN; membrane-anchored junction protein"
					}
					]
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"K23311  CTC1; CST complex subunit CTC1"
					},
					{
						"name":"K23312  STN1; CST complex subunit STN1"
					},
					{
						"name":"K23313  TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)",
					"children":[
					{
						"name":"K11115  CDC13; cell division control protein 13"
					},
					{
						"name":"K11117  STN1; protein STN1"
					},
					{
						"name":"K11116  TEN1; telomere length regulation protein"
					}
					]
				},
				{
					"name":"RIF proteins",
					"children":[
					{
						"name":"K11118  RIF1; RAP1-interacting factor 1"
					},
					{
						"name":"K11119  RIF2; RAP1-interacting factor 2"
					}
					]
				},
				{
					"name":"SIR proteins",
					"children":[
					{
						"name":"K11120  SIR1; regulatory protein SIR1"
					},
					{
						"name":"K11121  SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]"
					},
					{
						"name":"K11122  SIR3; regulatory protein SIR3"
					},
					{
						"name":"K11123  SIR4; regulatory protein SIR4"
					}
					]
				},
				{
					"name":"K09426  RAP1; Myb-like DNA-binding protein RAP1"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"K11124  SMG6, EST1A; protein SMG6 [EC:3.1.-.-]"
				},
				{
					"name":"K11125  SMG5, EST1B; protein SMG5"
				},
				{
					"name":"K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"K11127  TEP1; telomerase protein component 1"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"K11128  GAR1, NOLA1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"K11129  NHP2, NOLA2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"K11130  NOP10, NOLA3; H\/ACA ribonucleoprotein complex subunit 3"
					},
					{
						"name":"K11131  DKC1, NOLA4, CBF5; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"K11132  EST1; telomere elongation protein [EC:2.7.7.-]"
				},
				{
					"name":"K11126  TERT, EST2; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"K11133  EST3; telomere replication protein"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"K11086  SNRPB, SMB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"K11087  SNRPD1, SMD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"K11096  SNRPD2, SMD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"K11088  SNRPD3, SMD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"K11097  SNRPE, SME; small nuclear ribonucleoprotein E"
					},
					{
						"name":"K11098  SNRPF, SMF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"K11099  SNRPG, SMG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"K11134  ELG1; telomere length regulation protein"
				},
				{
					"name":"K10755  RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"K10756  RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"K10865  MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"K10866  RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"K10867  NBN, NBS1; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"K04728  ATM, TEL1; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"K10900  WRN, RECQL2; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"K10901  BLM, RECQL3, SGS1; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"K06642  PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]"
				},
				{
					"name":"K10848  ERCC4, XPF; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"K24070  PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"K28005  PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"K10799  TNKS; tankyrase [EC:2.4.2.30]"
				},
				{
					"name":"K11135  PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"K11136  RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"K11137  TELO2, TEL2; telomere length regulation protein"
				},
				{
					"name":"K01149  TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]"
				},
				{
					"name":"K11138  RIF1; telomere-associated protein RIF1"
				},
				{
					"name":"K15255  PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]"
				},
				{
					"name":"K21772  PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"K21800  PURG; purine-rich element-binding protein gamma"
				},
				{
					"name":"K23314  WRAP53, TCAB1; telomerase Cajal body protein 1"
				},
				{
					"name":"K25059  SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"K25186  RTF2; replication termination factor 2"
				},
				{
					"name":"K22485  TBF1; protein TBF1"
				},
				{
					"name":"K28506  GBP2, HRB1; serine\/arginine (SR)-type shuttling mRNA binding protein"
				},
				{
					"name":"K28514  TCG1; single-stranded TG1-3 DNA-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"K03163  TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"K03164  TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"K03165  TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"K05787  hupA; DNA-binding protein HU-alpha"
				},
				{
					"name":"K03530  hupB; DNA-binding protein HU-beta"
				},
				{
					"name":"K04764  ihfA, himA; integration host factor subunit alpha"
				},
				{
					"name":"K05788  ihfB, himD; integration host factor subunit beta"
				},
				{
					"name":"K02313  dnaA; chromosomal replication initiator protein"
				},
				{
					"name":"K02314  dnaB; replicative DNA helicase [EC:5.6.2.3]"
				},
				{
					"name":"K02315  dnaC; DNA replication protein DnaC"
				},
				{
					"name":"K02316  dnaG; DNA primase [EC:2.7.7.101]"
				},
				{
					"name":"K03346  dnaB; replication initiation and membrane attachment protein"
				},
				{
					"name":"K11144  dnaI; primosomal protein DnaI"
				},
				{
					"name":"K18996  repC; replication initiation protein RepC"
				},
				{
					"name":"K03111  ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)",
				"children":[
				{
					"name":"K10725  cdc6A; archaeal cell division control protein 6"
				},
				{
					"name":"K10726  mcm; replicative DNA helicase Mcm [EC:5.6.2.3]"
				},
				{
					"name":"K02683  priS, pri1, priA; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"K18882  priL, pri2, priB; DNA primase large subunit"
				},
				{
					"name":"K09723  ginS; DNA replication factor GINS"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme",
					"children":[
					{
						"name":"K02337  dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]"
					},
					{
						"name":"K03763  polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]"
					},
					{
						"name":"K02338  dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]"
					},
					{
						"name":"K02339  holC; DNA polymerase III subunit chi [EC:2.7.7.7]"
					},
					{
						"name":"K02340  holA; DNA polymerase III subunit delta [EC:2.7.7.7]"
					},
					{
						"name":"K02341  holB; DNA polymerase III subunit delta' [EC:2.7.7.7]"
					},
					{
						"name":"K02342  dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]"
					},
					{
						"name":"K14159  rnhA-dnaQ; ribonuclease HI \/ DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]"
					},
					{
						"name":"K02343  dnaX; DNA polymerase III subunit gamma\/tau [EC:2.7.7.7]"
					},
					{
						"name":"K02344  holD; DNA polymerase III subunit psi [EC:2.7.7.7]"
					},
					{
						"name":"K02345  holE; DNA polymerase III subunit theta [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"RNase H",
					"children":[
					{
						"name":"K03469  rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]"
					},
					{
						"name":"K14159  rnhA-dnaQ; ribonuclease HI \/ DNA polymerase III subunit epsilon [EC:3.1.26.4 2.7.7.7]"
					},
					{
						"name":"K22316  rhnA-cobC; ribonuclease H \/ adenosylcobalamin\/alpha-ribazole phosphatase [EC:3.1.26.4 3.1.3.73]"
					},
					{
						"name":"K03470  rnhB; ribonuclease HII [EC:3.1.26.4]"
					},
					{
						"name":"K03471  rnhC; ribonuclease HIII [EC:3.1.26.4]"
					}
					]
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"K02335  polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"K01972  E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]"
					},
					{
						"name":"K23786  exoA; 5'-3' exonuclease [EC:3.1.11.-]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases",
					"children":[
					{
						"name":"K02319  pol; DNA polymerase, archaea type [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"D-family DNA polymerases",
					"children":[
					{
						"name":"K02322  polC; DNA polymerase II large subunit [EC:2.7.7.7]"
					},
					{
						"name":"K02323  polB; DNA polymerase II small subunit [EC:2.7.7.7]"
					}
					]
				},
				{
					"name":"RNase H",
					"children":[
					{
						"name":"K03469  rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]"
					},
					{
						"name":"K03470  rnhB; ribonuclease HII [EC:3.1.26.4]"
					}
					]
				},
				{
					"name":"RFC (replication factor C)",
					"children":[
					{
						"name":"K04800  rfcL; replication factor C large subunit"
					},
					{
						"name":"K04801  rfcS; replication factor C small subunit"
					}
					]
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"K10742  DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"K04799  FEN1, RAD2; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"K10747  LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein",
				"children":[
				{
					"name":"K10748  tus, tau; DNA replication terminus site-binding protein"
				}
				]
			},
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"K06223  dam; DNA adenine methylase [EC:2.1.1.72]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"K03645  seqA; negative modulator of initiation of replication"
				},
				{
					"name":"K10763  hda; DnaA-homolog protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"K02469  gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"K02470  gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"K02621  parC; topoisomerase IV subunit A [EC:5.6.2.2]"
			},
			{
				"name":"K02622  parE; topoisomerase IV subunit B [EC:5.6.2.2]"
			},
			{
				"name":"K03166  top6A; DNA topoisomerase VI subunit A [EC:5.6.2.2]"
			},
			{
				"name":"K03167  top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			},
			{
				"name":"K03168  topA; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"K03169  topB; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"K03170  topG, rgy; reverse gyrase [EC:5.6.2.2 5.6.2.-]"
			}
			]
		}
		]
	}
	]
}