{
	"name":"ko03051",
	"children":[
	{
		"name":"Eukaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"alpha type subunits",
				"children":[
				{
					"name":"K02730  PSMA6; 20S proteasome subunit alpha 1 [EC:3.4.25.1]"
				},
				{
					"name":"K02726  PSMA2; 20S proteasome subunit alpha 2 [EC:3.4.25.1]"
				},
				{
					"name":"K02728  PSMA4; 20S proteasome subunit alpha 3 [EC:3.4.25.1]"
				},
				{
					"name":"K02731  PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"K02729  PSMA5; 20S proteasome subunit alpha 5 [EC:3.4.25.1]"
				},
				{
					"name":"K02725  PSMA1; 20S proteasome subunit alpha 6 [EC:3.4.25.1]"
				},
				{
					"name":"K02727  PSMA3; 20S proteasome subunit alpha 7 [EC:3.4.25.1]"
				}
				]
			},
			{
				"name":"beta type subunits",
				"children":[
				{
					"name":"K02738  PSMB6; 20S proteasome subunit beta 1 [EC:3.4.25.1]"
				},
				{
					"name":"K02739  PSMB7; 20S proteasome subunit beta 2 [EC:3.4.25.1]"
				},
				{
					"name":"K02735  PSMB3; 20S proteasome subunit beta 3 [EC:3.4.25.1]"
				},
				{
					"name":"K02734  PSMB2; 20S proteasome subunit beta 4 [EC:3.4.25.1]"
				},
				{
					"name":"K02737  PSMB5; 20S proteasome subunit beta 5 [EC:3.4.25.1]"
				},
				{
					"name":"K02732  PSMB1; 20S proteasome subunit beta 6 [EC:3.4.25.1]"
				},
				{
					"name":"K02736  PSMB4; 20S proteasome subunit beta 7 [EC:3.4.25.1]"
				},
				{
					"name":"K02740  PSMB8, LMP7; 20S proteasome subunit beta 8 [EC:3.4.25.1]"
				},
				{
					"name":"K02741  PSMB9, LMP2; 20S proteasome subunit beta 9 [EC:3.4.25.1]"
				},
				{
					"name":"K02733  PSMB10, MECL1; 20S proteasome subunit beta 10 [EC:3.4.25.1]"
				},
				{
					"name":"K11598  PSMB11; 20S proteasome subunit beta 11 [EC:3.4.25.1]"
				}
				]
			}
			]
		},
		{
			"name":"Regulatory particles",
			"children":[
			{
				"name":"PA700 (19S proteasome)",
				"children":[
				{
					"name":"ATPase subunits",
					"children":[
					{
						"name":"K03061  PSMC2, RPT1; 26S proteasome regulatory subunit T1"
					},
					{
						"name":"K03062  PSMC1, RPT2; 26S proteasome regulatory subunit T2"
					},
					{
						"name":"K03063  PSMC4, RPT3; 26S proteasome regulatory subunit T3"
					},
					{
						"name":"K03064  PSMC6, RPT4; 26S proteasome regulatory subunit T4"
					},
					{
						"name":"K03065  PSMC3, RPT5; 26S proteasome regulatory subunit T5"
					},
					{
						"name":"K03066  PSMC5, RPT6; 26S proteasome regulatory subunit T6"
					}
					]
				},
				{
					"name":"non-ATPase subunits",
					"children":[
					{
						"name":"K03028  PSMD2, RPN1; 26S proteasome regulatory subunit N1"
					},
					{
						"name":"K03032  PSMD1, RPN2; 26S proteasome regulatory subunit N2"
					},
					{
						"name":"K03033  PSMD3, RPN3; 26S proteasome regulatory subunit N3"
					},
					{
						"name":"K06693  PSMD9, RPN4; 26S proteasome regulatory subunit N4"
					},
					{
						"name":"K03035  PSMD12, RPN5; 26S proteasome regulatory subunit N5"
					},
					{
						"name":"K03036  PSMD11, RPN6; 26S proteasome regulatory subunit N6"
					},
					{
						"name":"K03037  PSMD6, RPN7; 26S proteasome regulatory subunit N7"
					},
					{
						"name":"K03038  PSMD7, RPN8; 26S proteasome regulatory subunit N8"
					},
					{
						"name":"K03039  PSMD13, RPN9; 26S proteasome regulatory subunit N9"
					},
					{
						"name":"K03029  PSMD4, RPN10; 26S proteasome regulatory subunit N10"
					},
					{
						"name":"K03030  PSMD14, RPN11, POH1; 26S proteasome regulatory subunit N11"
					},
					{
						"name":"K03031  PSMD8, RPN12; 26S proteasome regulatory subunit N12"
					},
					{
						"name":"K06691  RPN13; 26S proteasome regulatory subunit N13"
					},
					{
						"name":"K10881  SHFM1, DSS1, RPN15; 26 proteasome complex subunit DSS1"
					},
					{
						"name":"K06692  PSMD5; 26S proteasome non-ATPase regulatory subunit 5"
					},
					{
						"name":"K06694  PSMD10; 26S proteasome non-ATPase regulatory subunit 10"
					}
					]
				}
				]
			},
			{
				"name":"PA28 (11S REG)",
				"children":[
				{
					"name":"K06696  PSME1; proteasome activator subunit 1 (PA28 alpha)"
				},
				{
					"name":"K06697  PSME2; proteasome activator subunit 2 (PA28 beta)"
				},
				{
					"name":"K06698  PSME3; proteasome activator subunit 3 (PA28 gamma)"
				}
				]
			},
			{
				"name":"PA200",
				"children":[
				{
					"name":"K06699  PSME4; proteasome activator subunit 4"
				}
				]
			},
			{
				"name":"PI31",
				"children":[
				{
					"name":"K06700  PSMF1; proteasome inhibitor subunit 1 (PI31)"
				}
				]
			}
			]
		},
		{
			"name":"Assembling factors",
			"children":[
			{
				"name":"Assembling chaperones",
				"children":[
				{
					"name":"K11599  POMP, UMP1; proteasome maturation protein"
				},
				{
					"name":"K11875  PSMG1, DSCR2, PAC1; proteasome assembly chaperone 1"
				},
				{
					"name":"K11876  PSMG2, PAC2; proteasome assembly chaperone 2"
				},
				{
					"name":"K11877  PSMG3, PAC3; proteasome assembly chaperone 3"
				},
				{
					"name":"K11878  PSMG4, PAC4; proteasome assembly chaperone 4"
				},
				{
					"name":"K11879  PBA1, POC1; proteasome chaperone 1"
				},
				{
					"name":"K11880  ADD66, PBA2, POC2; proteasome chaperone 2"
				},
				{
					"name":"K11881  IRC25, POC3; proteasome chaperone 3"
				},
				{
					"name":"K11882  POC4; proteasome chaperone 4"
				}
				]
			},
			{
				"name":"Other assembling factors",
				"children":[
				{
					"name":"K03250  EIF3E, INT6; translation initiation factor 3 subunit E"
				},
				{
					"name":"K03283  HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"K26598  HSPA2; heat shock 70kDa protein 2"
				},
				{
					"name":"K04079  HSP90A, htpG; molecular chaperone HtpG"
				},
				{
					"name":"K04687  IFNG; interferon gamma"
				},
				{
					"name":"K11883  NOB1; RNA-binding protein NOB1"
				},
				{
					"name":"K11884  PNO1, DIM2; RNA-binding protein PNO1"
				}
				]
			}
			]
		},
		{
			"name":"Proteasome interacting proteins (PIPs)",
			"children":[
			{
				"name":"UBL-UBA shuttle proteins",
				"children":[
				{
					"name":"K10839  RAD23, HR23; UV excision repair protein RAD23"
				},
				{
					"name":"K04523  UBQLN, DSK2; ubiquilin"
				},
				{
					"name":"K22254  UBQLNL; ubiquilin-like protein"
				},
				{
					"name":"K11885  DDI; DNA damage-inducible protein [EC:3.4.23.-]"
				},
				{
					"name":"K29014  NUB1; NEDD8 ultimate buster 1"
				}
				]
			},
			{
				"name":"Other PIPs",
				"children":[
				{
					"name":"K11886  ECM29; proteasome component ECM29"
				},
				{
					"name":"K11887  PAAF1, RPN14; proteasomal ATPase-associated factor 1"
				},
				{
					"name":"K03034  RPN4; protein RPN4"
				},
				{
					"name":"K06695  PSMC3IP; 26S proteasome regulatory subunit, ATPase 3, interacting protein"
				},
				{
					"name":"K28966  JKAMP; JNK1\/MAPK8-associated membrane protein"
				},
				{
					"name":"K11888  CUT8, STS1; protein Cut8"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic proteasome",
		"children":[
		{
			"name":"Core particles (20S proteasome)",
			"children":[
			{
				"name":"K03432  psmA, prcA; proteasome alpha subunit [EC:3.4.25.1]"
			},
			{
				"name":"K03433  psmB, prcB; proteasome beta subunit [EC:3.4.25.1]"
			}
			]
		},
		{
			"name":"Bacterial regulatory particles",
			"children":[
			{
				"name":"K13527  mpa; proteasome-associated ATPase"
			},
			{
				"name":"K13571  pafA; proteasome accessory factor A [EC:6.3.1.19]"
			},
			{
				"name":"K13572  pafB; proteasome accessory factor B"
			},
			{
				"name":"K13573  pafC; proteasome accessory factor C"
			},
			{
				"name":"K24033  pafBC; proteasome accessory factor BC"
			},
			{
				"name":"K20814  dop; Pup amidohydrolase [EC:3.5.1.119]"
			}
			]
		},
		{
			"name":"Archaeal regulatory particles",
			"children":[
			{
				"name":"K03420  psmR; proteasome regulatory subunit"
			}
			]
		}
		]
	}
	]
}