{
	"name":"sce04131",
	"children":[
	{
		"name":"Exocytosis",
		"children":[
		{
			"name":"Calcium ion-dependent exocytosis",
			"children":[
			{
				"name":"Synaptotagmins"
			},
			{
				"name":"Septins",
				"children":[
				{
					"name":"YLR314C CDC3; septin CDC3\tK16944 SEPT7; septin 7"
				}
				]
			},
			{
				"name":"DOC-2 proteins"
			},
			{
				"name":"Acrosomal exocytosis proteins",
				"children":[
				{
					"name":"YDR466W PKH3; protein kinase PKH3\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				},
				{
					"name":"YDR490C PKH1; serine\/threonine protein kinase PKH1\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				},
				{
					"name":"YOL100W PKH2; serine\/threonine protein kinase PKH2\tK06276 PDPK1; 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipases",
				"children":[
				{
					"name":"YPL268W PLC1; phosphatidylinositol phospholipase C\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				},
				{
					"name":"YKR031C SPO14; phospholipase D\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				}
				]
			},
			{
				"name":"Kinases and associated proteins",
				"children":[
				{
					"name":"YDR208W MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"YHL007C STE20; mitogen-activated protein kinase kinase kinase kinase STE20\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				},
				{
					"name":"YKL067W YNK1; nucleoside diphosphate kinase\tK00940 ndk; nucleoside-diphosphate kinase [EC:2.7.4.6]"
				},
				{
					"name":"YDR122W KIN1; serine\/threonine protein kinase KIN1\tK19852 KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
				},
				{
					"name":"YLR096W KIN2; serine\/threonine protein kinase KIN2\tK19852 KIN1_2; serine\/threonine protein kinase KIN1\/2 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YDR373W FRQ1; frequenin\tK19932 NCS1; neuronal calcium sensor"
				}
				]
			}
			]
		},
		{
			"name":"Small GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YFL005W SEC4; Rab family GTPase SEC4\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YBR109C CMD1; calmodulin\tK02183 CALM; calmodulin"
				},
				{
					"name":"YNL272C SEC2; guanine nucleotide exchange factor SEC2\tK19940 SEC2; Rab guanine nucleotide exchange factor SEC2"
				},
				{
					"name":"YDR164C SEC1; Sec1p\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"YBL106C SRO77; putative Rab GTPase-binding protein SRO77\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"YPR032W SRO7; Rab GTPase-binding protein SRO7\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"YPR017C DSS4; guanine nucleotide exchange factor DSS4\tK19952 RABIF; guanine nucleotide exchange factor"
				},
				{
					"name":"YNL293W MSB3; Rab GTPase-activating protein MSB3\tK19953 GRTP1; TBC1 domain family member 6"
				},
				{
					"name":"YOL112W MSB4; Rab GTPase-activating protein MSB4\tK19953 GRTP1; TBC1 domain family member 6"
				},
				{
					"name":"YGR100W MDR1; GTPase-activating protein MDR1\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"YDR244W PEX5; Pex5p\tK13342 PEX5; peroxin-5"
				},
				{
					"name":"YOR370C MRS6; GTPase-activating protein MRS6\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"YJL031C BET4; Rab geranylgeranyltransferase BET4\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"YPR176C BET2; Rab geranylgeranyltransferase BET2\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"YJR033C RAV1; Rav1p\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"Rho GTPases",
				"children":[
				{
					"name":"YLR229C CDC42; Rho family GTPase CDC42\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Other small GTPases and associated proteins"
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Exocyst complex",
				"children":[
				{
					"name":"YER008C SEC3; GTP-Rho binding exocyst subunit SEC3\tK19983 EXOC1; exocyst complex component 1"
				},
				{
					"name":"YDR166C SEC5; exocyst subunit SEC5\tK17637 EXOC2; exocyst complex component 2"
				},
				{
					"name":"YIL068C SEC6; SNARE-binding exocyst subunit SEC6\tK06110 EXOC3; exocyst complex component 3"
				},
				{
					"name":"YPR055W SEC8; exocyst subunit SEC8\tK06111 EXOC4; exocyst complex component 4"
				},
				{
					"name":"YLR166C SEC10; exocyst subunit SEC10\tK19984 EXOC5; exocyst complex component 5"
				},
				{
					"name":"YGL233W SEC15; Rab GTPase-binding exocyst subunit SEC15\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"YJL085W EXO70; GTP-Rho binding exocyst subunit EXO70\tK07195 EXOC7; exocyst complex component 7"
				},
				{
					"name":"YBR102C EXO84; exocyst subunit EXO84\tK19986 EXOC8; exocyst complex component 8"
				}
				]
			},
			{
				"name":"Exocyst complex assembly proteins",
				"children":[
				{
					"name":"YDR363W-A SEM1; proteasome regulatory particle lid subunit SEM1\tK10881 SHFM1; 26 proteasome complex subunit DSS1"
				},
				{
					"name":"YIL138C TPM2; tropomyosin TPM2\tK17945 TPM1_2; tropomyosin, fungi type"
				},
				{
					"name":"YNL079C TPM1; tropomyosin TPM1\tK17945 TPM1_2; tropomyosin, fungi type"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Exomer complex",
				"children":[
				{
					"name":"YLR330W CHS5; Chs5p\tK19877 CHS5; chitin biosynthesis protein CHS5"
				},
				{
					"name":"YJL099W CHS6; Chs6p\tK19880 CHS6; Chs5-Arf1p-binding protein CHS6\/BCH2"
				},
				{
					"name":"YKR027W BCH2; Bch2p\tK19880 CHS6; Chs5-Arf1p-binding protein CHS6\/BCH2"
				},
				{
					"name":"YMR237W BCH1; exomer complex subunit\tK19881 BUD7; Chs5-Arf1p-binding protein BUD7\/BCH1"
				},
				{
					"name":"YOR299W BUD7; exomer complex subunit\tK19881 BUD7; Chs5-Arf1p-binding protein BUD7\/BCH1"
				}
				]
			},
			{
				"name":"ER-PM contacts associated proteins",
				"children":[
				{
					"name":"YLR087C CSF1; Csf1p\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				},
				{
					"name":"YML072C TCB3; Tcb3p\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"YNL087W TCB2; tricalbin\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"YOR086C TCB1; tricalbin\tK28063 ESYT; extended synaptotagmin"
				},
				{
					"name":"YBL091C-A SCS22; phospholipid metabolism-regulating protein SCS22\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				},
				{
					"name":"YER120W SCS2; phosphatidylinositol-binding protein SCS2\tK29085 SCS2_22; vesicle-associated membrane protein-associated protein"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YNR049C MSO1; Mso1p\tK19992 MSO1; protein MSO1"
				},
				{
					"name":"YDR323C PEP7; phosphatidylinositol-3-phosphate binding protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"YJL145W SFH5; Sfh5p\tK19996 SFH5; phosphatidylinositol transfer protein SFH5"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"SNARE",
		"children":[
		{
			"name":"Syntaxin (Qa)",
			"children":[
			{
				"name":"Stx-PM",
				"children":[
				{
					"name":"YMR183C SSO2; syntaxin\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
				},
				{
					"name":"YPL232W SSO1; syntaxin\tK08486 STX1B_2_3; syntaxin 1B\/2\/3"
				}
				]
			},
			{
				"name":"Stx-Endo",
				"children":[
				{
					"name":"YOR106W VAM3; SNAP receptor VAM3\tK21155 VAM3; syntaxin VAM3"
				}
				]
			},
			{
				"name":"Stx-TGN \/ EE",
				"children":[
				{
					"name":"YOL018C TLG2; Tlg2p\tK08489 STX16; syntaxin 16"
				}
				]
			},
			{
				"name":"Stx-cisGolgi",
				"children":[
				{
					"name":"YLR026C SED5; t-SNARE syntaxin\tK08490 STX5; syntaxin 5"
				}
				]
			},
			{
				"name":"Stx-sER"
			},
			{
				"name":"Stx-rER",
				"children":[
				{
					"name":"YOR075W UFE1; Ufe1p\tK08492 STX18; syntaxin 18"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[N] (Qb)",
			"children":[
			{
				"name":"Vti1",
				"children":[
				{
					"name":"YMR197C VTI1; v-SNARE protein VTI1\tK08493 VTI1; vesicle transport through interaction with t-SNAREs 1"
				}
				]
			},
			{
				"name":"NPSN"
			},
			{
				"name":"Gos1 (Gos28)",
				"children":[
				{
					"name":"YHL031C GOS1; Gos1p\tK08495 GOSR1; golgi SNAP receptor complex member 1"
				}
				]
			},
			{
				"name":"Bos1 \/ Membrin",
				"children":[
				{
					"name":"YLR078C BOS1; Bos1p\tK08496 GOSR2; golgi SNAP receptor complex member 2"
				}
				]
			},
			{
				"name":"Sec20",
				"children":[
				{
					"name":"YDR498C SEC20; Sec20p\tK08497 SEC20; protein transport protein SEC20"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25[C] (Qc)",
			"children":[
			{
				"name":"STX6",
				"children":[
				{
					"name":"YDR468C TLG1; Tlg1p\tK08499 TLG1; member of the syntaxin family of t-SNAREs"
				}
				]
			},
			{
				"name":"STX8",
				"children":[
				{
					"name":"YAL014C SYN8; syntaxin\tK08501 STX8; syntaxin 8"
				},
				{
					"name":"YGL212W VAM7; Vam7p\tK08502 VAM7; regulator of vacuolar morphogenesis"
				}
				]
			},
			{
				"name":"STX10"
			},
			{
				"name":"Bet1",
				"children":[
				{
					"name":"YIL004C BET1; Bet1p\tK08504 BET1; blocked early in transport 1"
				}
				]
			},
			{
				"name":"Sft1",
				"children":[
				{
					"name":"YKL006C-A SFT1; Sft1p\tK08505 SFT1; protein transport protein SFT1"
				}
				]
			},
			{
				"name":"Syp7"
			},
			{
				"name":"Use1",
				"children":[
				{
					"name":"YGL098W USE1; SNAP receptor USE1\tK08507 USE1; unconventional SNARE in the endoplasmic reticulum protein 1"
				}
				]
			}
			]
		},
		{
			"name":"SNAP-25 (Qb,c)",
			"children":[
			{
				"name":"SNAP-23"
			},
			{
				"name":"SNAP-25",
				"children":[
				{
					"name":"YGR009C SEC9; Sec9p\tK19950 SEC9; protein transport protein SEC9"
				}
				]
			},
			{
				"name":"SNAP-29"
			},
			{
				"name":"SNAP-47"
			}
			]
		},
		{
			"name":"VAMP, Ykt6, Sec22 (R)",
			"children":[
			{
				"name":"VAMP",
				"children":[
				{
					"name":"YAL030W SNC1; SNAP receptor SNC1\tK08513 VAMP4; vesicle-associated membrane protein 4"
				},
				{
					"name":"YOR327C SNC2; SNAP receptor SNC2\tK08513 VAMP4; vesicle-associated membrane protein 4"
				},
				{
					"name":"YLR093C NYV1; Nyv1p\tK08564 NYV1; vacuolar v-SNARE NYV1"
				}
				]
			},
			{
				"name":"Ykt6",
				"children":[
				{
					"name":"YKL196C YKT6; palmitoyltransferase YKT6\tK08516 YKT6; synaptobrevin homolog YKT6"
				}
				]
			},
			{
				"name":"Sec22",
				"children":[
				{
					"name":"YLR268W SEC22; SNAP receptor SEC22\tK08517 SEC22; vesicle transport protein SEC22"
				}
				]
			},
			{
				"name":"Tomosyn",
				"children":[
				{
					"name":"YBL106C SRO77; putative Rab GTPase-binding protein SRO77\tK08518 STXBP5; syntaxin-binding protein 5"
				},
				{
					"name":"YPR032W SRO7; Rab GTPase-binding protein SRO7\tK08518 STXBP5; syntaxin-binding protein 5"
				}
				]
			},
			{
				"name":"Putative SNAREs"
			}
			]
		},
		{
			"name":"SNARE associated proteins",
			"children":[
			{
				"name":"Syntaxin-binding proteins",
				"children":[
				{
					"name":"YDR164C SEC1; Sec1p\tK15292 STXBP1; syntaxin-binding protein 1"
				},
				{
					"name":"YDR189W SLY1; syntaxin-binding protein\tK19998 SCFD1; sec1 family domain-containing protein 1"
				}
				]
			},
			{
				"name":"Palmitoyltransferases",
				"children":[
				{
					"name":"YNL326C PFA3; palmitoyltransferase PFA3\tK20028 ZDHHC2_15_20; palmitoyltransferase ZDHHC2\/15\/20 [EC:2.3.1.225]"
				},
				{
					"name":"YDR126W SWF1; palmitoyltransferase SWF1\tK20003 ZDHHC4; palmitoyltransferase ZDHHC4 [EC:2.3.1.225]"
				},
				{
					"name":"YDR264C AKR1; palmitoyltransferase AKR1\tK20032 ZDHHC13_17; palmitoyltransferase ZDHHC13\/17 [EC:2.3.1.225]"
				},
				{
					"name":"YOR034C AKR2; putative palmitoyltransferase AKR2\tK20032 ZDHHC13_17; palmitoyltransferase ZDHHC13\/17 [EC:2.3.1.225]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YBR080C SEC18; AAA family ATPase SEC18\tK06027 NSF; vesicle-fusing ATPase [EC:3.6.4.6]"
				},
				{
					"name":"YBL050W SEC17; Sec17p\tK15296 NAPA; alpha-soluble NSF attachment protein"
				},
				{
					"name":"YJL036W SNX4; Snx4p\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"YDL113C ATG20; Atg20p\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"YDR425W SNX41; Snx41p\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"YDR372C VPS74; Vps74p\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"YDL126C CDC48; AAA family ATPase CDC48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"YBL058W SHP1; protein phosphatase regulator SHP1\tK14012 NSFL1C; UBX domain-containing protein 1"
				},
				{
					"name":"YOR359W VTS1; Vts1p\tK27407 VTS1; RNA-binding protein VTS1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endocytosis",
		"children":[
		{
			"name":"Clathrin-mediated endocytosis",
			"children":[
			{
				"name":"Clathrin",
				"children":[
				{
					"name":"YGL206C CHC1; clathrin heavy chain\tK04646 CLTC; clathrin heavy chain"
				}
				]
			},
			{
				"name":"Dynamin",
				"children":[
				{
					"name":"YLL001W DNM1; dynamin-related GTPase DNM1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			},
			{
				"name":"AP-2 complex",
				"children":[
				{
					"name":"YBL037W APL3; Apl3p\tK11824 AP2A; AP-2 complex subunit alpha"
				},
				{
					"name":"YJR005W APL1; Apl1p\tK11825 AP2B1; AP-2 complex subunit beta-1"
				},
				{
					"name":"YOL062C APM4; Apm4p\tK11826 AP2M1; AP-2 complex subunit mu-1"
				},
				{
					"name":"YJR058C APS2; Aps2p\tK11827 AP2S1; AP-2 complex subunit sigma-1"
				}
				]
			},
			{
				"name":"Other core components",
				"children":[
				{
					"name":"YCR030C SYP1; Syp1p\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"YDL161W ENT1; epsin\tK12471 EPN; epsin"
				},
				{
					"name":"YDR153C ENT5; Ent5p\tK12471 EPN; epsin"
				},
				{
					"name":"YJR125C ENT3; Ent3p\tK12471 EPN; epsin"
				},
				{
					"name":"YLR206W ENT2; epsin\tK12471 EPN; epsin"
				},
				{
					"name":"YBL047C EDE1; Ede1p\tK12472 EPS15; epidermal growth factor receptor substrate 15"
				},
				{
					"name":"YGR241C Yap1802p\tK20044 PICALM; phosphatidylinositol-binding clathrin assembly protein"
				},
				{
					"name":"YHR161C Yap1801p\tK20044 PICALM; phosphatidylinositol-binding clathrin assembly protein"
				},
				{
					"name":"YDR388W RVS167; amphiphysin\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"YBL007C SLA1; cytoskeletal protein-binding protein SLA1\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"YIR006C PAN1; Pan1p\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"YNL084C END3; End3p\tK20048 END3; actin cytoskeleton-regulatory complex protein END3"
				},
				{
					"name":"YAL005C SSA1; Hsp70 family ATPase SSA1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YBL075C SSA3; Hsp70 family ATPase SSA3\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YDL229W SSB1; Hsp70 family ATPase SSB1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YER103W SSA4; Hsp70 family chaperone SSA4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YLL024C SSA2; Hsp70 family chaperone SSA2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YNL209W SSB2; Hsp70 family ATPase SSB2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				}
				]
			},
			{
				"name":"Low-density lipoprotein receptor (LDLR) family proteins"
			},
			{
				"name":"LDLR adaptor proteins",
				"children":[
				{
					"name":"YDR208W MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				}
				]
			},
			{
				"name":"GPCR adaptor proteins",
				"children":[
				{
					"name":"YOR322C LDB19; Ldb19p\tK20059 LDB19; arrestin-related trafficking adapter 1"
				},
				{
					"name":"YBL101C ECM21; Ecm21p\tK20060 ECM21; arrestin-related trafficking adapter 2\/8"
				},
				{
					"name":"YPR030W CSR2; Csr2p\tK20060 ECM21; arrestin-related trafficking adapter 2\/8"
				},
				{
					"name":"YJL084C ALY2; Aly2p\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"YKR021W ALY1; Aly1p\tK20061 ALY1_2; arrestin-related trafficking adapter 3\/6"
				},
				{
					"name":"YFR022W ROG3; Rog3p\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"YGR068C ART5; Art5p\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"YOR018W ROD1; Rod1p\tK20062 ART4_5_7; arrestin-related trafficking adapter 4\/5\/7"
				},
				{
					"name":"YGL045W RIM8; Rim8p\tK20063 RIM8; arrestin-related trafficking adapter 9"
				}
				]
			},
			{
				"name":"Receptor tyrosine kinase (RTK) adaptor proteins"
			},
			{
				"name":"Inositol 5-phosphatases",
				"children":[
				{
					"name":"YIL002C INP51; phosphoinositide 5-phosphatase INP51\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				},
				{
					"name":"YNL106C INP52; phosphatidylinositol-3-\/phosphoinositide 5-phosphatase INP52\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				},
				{
					"name":"YOR109W INP53; phosphatidylinositol-3-\/phosphoinositide 5-phosphatase INP53\tK20279 SYNJ; synaptojanin [EC:3.1.3.36]"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"YIL095W PRK1; serine\/threonine protein kinase PRK1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"YNL020C ARK1; serine\/threonine protein kinase ARK1\tK08853 AAK; AP2-associated kinase [EC:2.7.11.1]"
				},
				{
					"name":"YGL083W SCY1; Scy1p\tK17541 SCYL2; SCY1-like protein 2"
				}
				]
			},
			{
				"name":"Ubiquitin E3 ligases",
				"children":[
				{
					"name":"YER125W RSP5; NEDD4 family E3 ubiquitin-protein ligase\tK10591 NEDD4; E3 ubiquitin-protein ligase NEDD4 [EC:2.3.2.26]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YNL243W SLA2; Sla2p\tK20040 HIP1R; huntingtin-interacting protein 1-related protein"
				},
				{
					"name":"YAL058W CNE1; calnexin\tK08054 CANX; calnexin"
				}
				]
			}
			]
		},
		{
			"name":"Lipid raft mediated endocytosis",
			"children":[
			{
				"name":"Caveolin-mediated endocytosis",
				"children":[
				{
					"name":"YLL001W DNM1; dynamin-related GTPase DNM1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				},
				{
					"name":"YBL105C PKC1; protein kinase C\tK02677 PRKCA; classical protein kinase C alpha type [EC:2.7.11.13]"
				}
				]
			},
			{
				"name":"Flotillin-dependent endocytosis"
			},
			{
				"name":"GRAF1-dependent endocytosis",
				"children":[
				{
					"name":"YLR229C CDC42; Rho family GTPase CDC42\tK04393 CDC42; cell division control protein 42"
				},
				{
					"name":"YDL137W ARF2; Arf family GTPase ARF2\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"YDL192W ARF1; Arf family GTPase ARF1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				}
				]
			},
			{
				"name":"Arf6-dependent endocytosis",
				"children":[
				{
					"name":"YOR094W ARF3; Arf family GTPase ARF3\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"RhoA-dependent endocytosis",
				"children":[
				{
					"name":"YPR165W RHO1; Rho family GTPase RHO1\tK04513 RHOA; Ras homolog gene family, member A"
				},
				{
					"name":"YLL001W DNM1; dynamin-related GTPase DNM1\tK17065 DNM1L; dynamin 1-like protein [EC:3.6.5.5]"
				}
				]
			}
			]
		},
		{
			"name":"Phagocytosis",
			"children":[
			{
				"name":"Fc receptors"
			},
			{
				"name":"Integrins (complement receptors)"
			},
			{
				"name":"Opsonins"
			},
			{
				"name":"Toll-like receptors"
			},
			{
				"name":"C-lectin receptors"
			},
			{
				"name":"Scavenger receptors"
			},
			{
				"name":"Coronins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YKL129C MYO3; myosin 3\tK10356 MYO1; myosin I"
				},
				{
					"name":"YMR109W MYO5; myosin 5\tK10356 MYO1; myosin I"
				}
				]
			}
			]
		},
		{
			"name":"Macropinocytosis",
			"children":[
			{
				"name":"Ras GTPases",
				"children":[
				{
					"name":"YNL098C RAS2; Ras family GTPase RAS2\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"YOR101W RAS1; Ras family GTPase RAS1\tK07827 KRAS; GTPase KRas"
				},
				{
					"name":"YLR229C CDC42; Rho family GTPase CDC42\tK04393 CDC42; cell division control protein 42"
				}
				]
			},
			{
				"name":"Kinases",
				"children":[
				{
					"name":"YLR240W VPS34; phosphatidylinositol 3-kinase VPS34\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"YFR019W FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"YHL007C STE20; mitogen-activated protein kinase kinase kinase kinase STE20\tK04409 PAK1; p21-activated kinase 1 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"Phospholipase C",
				"children":[
				{
					"name":"YPL268W PLC1; phosphatidylinositol phospholipase C\tK05857 PLCD; phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]"
				}
				]
			},
			{
				"name":"Sorting nexins",
				"children":[
				{
					"name":"YOR069W VPS5; sorting nexin 1\tK17917 SNX1_2; sorting nexin-1\/2"
				}
				]
			},
			{
				"name":"Others"
			}
			]
		},
		{
			"name":"Bin\/Amphiphysin\/Rvs (BAR) family proteins",
			"children":[
			{
				"name":"N-BAR proteins",
				"children":[
				{
					"name":"YDR388W RVS167; amphiphysin\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"YCR009C RVS161; amphiphysin-like protein RVS161\tK20120 BIN3; bridging integrator 3"
				}
				]
			},
			{
				"name":"F-BAR proteins",
				"children":[
				{
					"name":"YHR114W BZZ1; Bzz1p\tK20121 FNBP1; formin-binding protein 1"
				},
				{
					"name":"YCR030C SYP1; Syp1p\tK20042 FCHO; F-BAR domain only protein"
				},
				{
					"name":"YBR260C RGD1; GTPase-activating protein RGD1\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"I-BAR proteins"
			}
			]
		},
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YKR014C YPT52; Rab family GTPase YPT52\tK07888 RAB5B; Ras-related protein Rab-5B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YML097C VPS9; guanine nucleotide exchange factor VPS9\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"YDR323C PEP7; phosphatidylinositol-3-phosphate binding protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"YLR240W VPS34; phosphatidylinositol 3-kinase VPS34\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"YBR097W VPS15; ubiquitin-binding serine\/threonine protein kinase VPS15\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"YGL095C VPS45; Vps45p\tK12479 VPS45; vacuolar protein sorting-associated protein 45"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"YDL137W ARF2; Arf family GTPase ARF2\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"YDL192W ARF1; Arf family GTPase ARF1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"YOR094W ARF3; Arf family GTPase ARF3\tK07941 ARF6; ADP-ribosylation factor 6"
				}
				]
			},
			{
				"name":"Arf associated proteins",
				"children":[
				{
					"name":"YGL181W GTS1; Gts1p\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"YIL044C AGE2; GTPase-activating protein AGE2\tK12486 SMAP; stromal membrane-associated protein"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Fucosyltransferase"
			},
			{
				"name":"EFR3-PI4KIII alpha complex and associated proteins",
				"children":[
				{
					"name":"YLR305C STT4; 1-phosphatidylinositol 4-kinase STT4\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"YMR212C EFR3; Efr3p\tK21842 EFR3; protein EFR3"
				},
				{
					"name":"YGR198W YPP1; Ypp1p\tK21845 YPP1; cargo-transport protein YPP1"
				}
				]
			},
			{
				"name":"Insulin-like growth factor-binding proteins"
			},
			{
				"name":"Others"
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Lysosome transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YKR014C YPT52; Rab family GTPase YPT52\tK07888 RAB5B; Ras-related protein Rab-5B"
				},
				{
					"name":"YML001W YPT7; Rab family GTPase YPT7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"FTS\/Hook\/FHIP (FHF) complex"
			},
			{
				"name":"FERRY complex"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YLR240W VPS34; phosphatidylinositol 3-kinase VPS34\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"YOL038W PRE6; proteasome core particle subunit alpha 4\tK02731 PSMA7; 20S proteasome subunit alpha 4 [EC:3.4.25.1]"
				},
				{
					"name":"YJL044C GYP6; GTPase-activating protein GYP6\tK18469 TBC1D5; TBC1 domain family member 5"
				},
				{
					"name":"YDL234C GYP7; GTPase-activating protein GYP7\tK20168 TBC1D15; TBC1 domain family member 15"
				},
				{
					"name":"YOR370C MRS6; GTPase-activating protein MRS6\tK23460 CHM; Rab proteins geranylgeranyltransferase component A"
				},
				{
					"name":"YJL031C BET4; Rab geranylgeranyltransferase BET4\tK14050 RABGGTA; geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60]"
				},
				{
					"name":"YPR176C BET2; Rab geranylgeranyltransferase BET2\tK05956 RABGGTB; geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60]"
				},
				{
					"name":"YDR372C VPS74; Vps74p\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases"
			},
			{
				"name":"BLOC-one-related complex (BORC)"
			},
			{
				"name":"N-acetyl transferase complex C (NatC)",
				"children":[
				{
					"name":"YPR051W MAK3; peptide alpha-N-acetyltransferase MAK3\tK00670 NAA30; N-alpha-acetyltransferase 30 [EC:2.3.1.256]"
				},
				{
					"name":"YEL053C MAK10; Mak10p\tK20823 NAA35; N-alpha-acetyltransferase 35, NatC auxiliary subunit"
				},
				{
					"name":"YCR020C-A MAK31; Mak31p\tK20824 NAA38; N-alpha-acetyltransferase 38, NatC auxiliary subunit"
				}
				]
			},
			{
				"name":"Other Arf associated proteins"
			}
			]
		},
		{
			"name":"Endosomal sorting complexes required for transport (ESCRT)",
			"children":[
			{
				"name":"ESCRT-0 complex",
				"children":[
				{
					"name":"YNR006W VPS27; ESCRT-0 subunit protein VPS27\tK12182 HGS; hepatocyte growth factor-regulated tyrosine kinase substrate"
				},
				{
					"name":"YHL002W HSE1; ESCRT-0 subunit protein HSE1\tK04705 STAM; signal transducing adaptor molecule"
				}
				]
			},
			{
				"name":"ESCRT-I complex",
				"children":[
				{
					"name":"YCL008C STP22; ubiquitin-binding ESCRT-I subunit protein STP22\tK12183 TSG101; ESCRT-I complex subunit TSG101"
				},
				{
					"name":"YPL065W VPS28; ESCRT-I subunit protein VPS28\tK12184 VPS28; ESCRT-I complex subunit VPS28"
				},
				{
					"name":"YGR206W MVB12; ubiquitin-binding ESCRT-I subunit protein MVB12\tK12187 MVB12; ESCRT-I complex subunit MVB12"
				}
				]
			},
			{
				"name":"ESCRT-II complex",
				"children":[
				{
					"name":"YPL002C SNF8; ESCRT-II subunit protein SNF8\tK12188 SNF8; ESCRT-II complex subunit VPS22"
				},
				{
					"name":"YJR102C VPS25; ESCRT-II subunit protein VPS25\tK12189 VPS25; ESCRT-II complex subunit VPS25"
				},
				{
					"name":"YLR417W VPS36; ESCRT-II subunit protein VPS36\tK12190 VPS36; ESCRT-II complex subunit VPS36"
				}
				]
			},
			{
				"name":"ESCRT-III complex",
				"children":[
				{
					"name":"YKR035W-A DID2; Did2p\tK12197 CHMP1; charged multivesicular body protein 1"
				},
				{
					"name":"YKL002W DID4; ESCRT-III subunit protein DID4\tK12191 CHMP2A; charged multivesicular body protein 2A"
				},
				{
					"name":"YKL041W VPS24; ESCRT-III subunit protein VPS24\tK12193 VPS24; charged multivesicular body protein 3"
				},
				{
					"name":"YLR025W SNF7; ESCRT-III subunit protein SNF7\tK12194 CHMP4A_B; charged multivesicular body protein 4A\/B"
				},
				{
					"name":"YDR486C VPS60; Vps60p\tK12198 CHMP5; charged multivesicular body protein 5"
				},
				{
					"name":"YMR077C VPS20; ESCRT-III subunit protein VPS20\tK12195 CHMP6; charged multivesicular body protein 6"
				},
				{
					"name":"YJL049W CHM7; Chm7p\tK15053 CHMP7; charged multivesicular body protein 7"
				},
				{
					"name":"YPR173C VPS4; AAA family ATPase VPS4\tK12196 VPS4; vacuolar protein-sorting-associated protein 4"
				}
				]
			},
			{
				"name":"ESCRT associated proteins",
				"children":[
				{
					"name":"YLR181C VTA1; Vta1p\tK12199 VTA1; vacuolar protein sorting-associated protein VTA1"
				},
				{
					"name":"YOR275C RIM20; Rim20p\tK12200 PDCD6IP; programmed cell death 6-interacting protein"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"CORVET complex",
				"children":[
				{
					"name":"YDR495C VPS3; CORVET complex subunit VPS3\tK20177 VPS3; vacuolar protein sorting-associated protein 3"
				},
				{
					"name":"YAL002W VPS8; CORVET complex membrane-binding subunit VPS8\tK20178 VPS8; vacuolar protein sorting-associated protein 8"
				},
				{
					"name":"YMR231W PEP5; tethering complex subunit PEP5\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"YPL045W VPS16; tethering complex subunit VPS16\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"YLR148W PEP3; tethering complex subunit PEP3\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"YLR396C VPS33; tethering complex ATP-binding subunit VPS33\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				}
				]
			},
			{
				"name":"Hops complex",
				"children":[
				{
					"name":"YMR231W PEP5; tethering complex subunit PEP5\tK20179 VPS11; vacuolar protein sorting-associated protein 11"
				},
				{
					"name":"YPL045W VPS16; tethering complex subunit VPS16\tK20180 VPS16; vacuolar protein sorting-associated protein 16"
				},
				{
					"name":"YLR148W PEP3; tethering complex subunit PEP3\tK20181 VPS18; vacuolar protein sorting-associated protein 18"
				},
				{
					"name":"YLR396C VPS33; tethering complex ATP-binding subunit VPS33\tK20182 VPS33A; vacuolar protein sorting-associated protein 33A"
				},
				{
					"name":"YDL077C VAM6; Vam6p\tK20183 VPS39; Vam6\/Vps39-like protein vacuolar protein sorting-associated protein 39"
				},
				{
					"name":"YDR080W VPS41; Vps41p\tK20184 VPS41; vacuolar protein sorting-associated protein 41"
				}
				]
			}
			]
		},
		{
			"name":"Acidification regulators",
			"children":[
			{
				"name":"Rabconnectin-3 complex",
				"children":[
				{
					"name":"YJR033C RAV1; Rav1p\tK24155 DMXL; rabconnectin-3a"
				}
				]
			},
			{
				"name":"RAVE complex",
				"children":[
				{
					"name":"YJR033C RAV1; Rav1p\tK24155 DMXL; rabconnectin-3a"
				},
				{
					"name":"YDR202C RAV2; Rav2p\tK25485 RAV2; regulator of V-ATPase in vacuolar membrane protein 2"
				},
				{
					"name":"YDR328C SKP1; SCF ubiquitin ligase subunit SKP1\tK03094 SKP1; S-phase kinase-associated protein 1"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"YPL195W APL5; Apl5p\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"YGR261C APL6; Apl6p\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"YBR288C APM3; Apm3p\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"YJL024C APS3; Aps3p\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"BLOC-1 complex"
			},
			{
				"name":"BLOC-1 complex (yeast)",
				"children":[
				{
					"name":"YKL061W BLI1; Bli1p\tK22238 BLI1; biogenesis of lysosome-related organelles complex 1 subunit BLI1"
				},
				{
					"name":"YLR408C BLS1; Bls1p\tK22239 BLS1; biogenesis of lysosome-related organelles complex 1 subunit BLS1"
				},
				{
					"name":"YDR357C CNL1; Cnl1p\tK22240 CNL1; biogenesis of lysosome-related organelles complex 1 subunit CNL1"
				},
				{
					"name":"YNL086W SNN1; Snn1p\tK22241 SNN1; biogenesis of lysosome-related organelles complex 1 subunit SNN1"
				},
				{
					"name":"YEL005C VAB2; Vab2p\tK22242 VAB2; biogenesis of lysosome-related organelles complex 1 subunit VAB2"
				},
				{
					"name":"YGL079W KXD1; Kxd1p\tK22243 KXD1; biogenesis of lysosome-related organelles complex 1 subunit KXD1"
				}
				]
			},
			{
				"name":"BLOC-2 complex"
			},
			{
				"name":"BLOC-3 complex"
			},
			{
				"name":"Ferlins"
			},
			{
				"name":"Lysosomal membrane proteins",
				"children":[
				{
					"name":"YOR291W YPK9; putative acid anhydride hydrolase\tK13526 ATP13A2; cation-transporting P-type ATPase 13A2 [EC:7.2.2.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YGL124C MON1; Mon1p\tK20195 MON1; vacuolar fusion protein MON1"
				},
				{
					"name":"YBR131W CCZ1; Ccz1p\tK21156 CCZ1; vacuolar fusion protein CCZ1, fungi type"
				},
				{
					"name":"YDR069C DOA4; ubiquitin-specific protease DOA4\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"YER144C UBP5; putative ubiquitin-specific protease UBP5\tK11839 USP8; ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12]"
				},
				{
					"name":"YJR044C VPS55; Vps55p\tK28212 LEPROT; OB-RGRP\/VPS55 family protein"
				},
				{
					"name":"YOL129W VPS68; Vps68p\tK29023 VPS68; vacuolar protein sorting-associated protein 68"
				},
				{
					"name":"YKR001C VPS1; dynamin-like GTPase VPS1\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"YCR032W BPH1; Bph1p\tK24781 BPH1; beige protein homolog 1"
				},
				{
					"name":"YNL054W VAC7; Vac7p\tK28440 VAC7; vacuolar segregation protein 7"
				},
				{
					"name":"YLR173W TAG1; Tag1p\tK28441 TAG1; protein TAG1"
				},
				{
					"name":"YKL124W SSH4; Ssh4p\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"YMR171C EAR1; Ear1p\tK28544 SSH4; SSH4 family protein"
				},
				{
					"name":"YBR005W RCR1; Rcr1p\tK28545 RCR; protein RCR"
				},
				{
					"name":"YDR003W RCR2; Rcr2p\tK28545 RCR; protein RCR"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Protein recycling",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YER031C YPT31; Rab family GTPase YPT31\tK07905 RAB11B; Ras-related protein Rab-11B"
				},
				{
					"name":"YGL210W YPT32; Rab family GTPase YPT32\tK07905 RAB11B; Ras-related protein Rab-11B"
				}
				]
			},
			{
				"name":"Rab4 associated proteins",
				"children":[
				{
					"name":"YDR323C PEP7; phosphatidylinositol-3-phosphate binding protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"YJL036W SNX4; Snx4p\tK17919 SNX4; sorting nexin-4"
				}
				]
			},
			{
				"name":"Rab11 associated proteins",
				"children":[
				{
					"name":"YMR102C LAF1; Laf1p\tK20241 WDR44; WD repeat-containing protein 44"
				},
				{
					"name":"YLR208W SEC13; GTPase-activating protein SEC13\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"YGL233W SEC15; Rab GTPase-binding exocyst subunit SEC15\tK19985 EXOC6; exocyst complex component 6"
				},
				{
					"name":"YPL249C GYP5; GTPase-activating protein GYP5\tK20242 EVI5; ecotropic viral integration site 5 protein"
				},
				{
					"name":"YDR372C VPS74; Vps74p\tK15620 GOLPH3; golgi phosphoprotein 3"
				}
				]
			},
			{
				"name":"Other Rab GTPase associated proteins",
				"children":[
				{
					"name":"YML097C VPS9; guanine nucleotide exchange factor VPS9\tK20131 RABGEF1; Rab5 GDP\/GTP exchange factor"
				},
				{
					"name":"YER095W RAD51; recombinase RAD51\tK04482 RAD51; DNA repair protein RAD51"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Glutamate receptor-interacting proteins (GRIPs)"
			},
			{
				"name":"GRIP associated proteins"
			},
			{
				"name":"EARP complex",
				"children":[
				{
					"name":"YDR484W VPS52; Vps52p\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"YJL029C VPS53; Vps53p\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				}
				]
			},
			{
				"name":"WASH complex",
				"children":[
				{
					"name":"YKL007W CAP1; Cap1p\tK10364 CAPZA; F-actin-capping protein subunit alpha"
				},
				{
					"name":"YIL034C CAP2; F-actin-capping protein subunit beta\tK10365 CAPZB; F-actin-capping protein subunit beta"
				}
				]
			},
			{
				"name":"Retriever complex",
				"children":[
				{
					"name":"YHR012W VPS29; retromer subunit VPS29\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				}
				]
			},
			{
				"name":"CCC complex"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YLR087C CSF1; Csf1p\tK24964 BLTP1; Bridge-like lipid transfer protein family member 1"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endosome - Golgi transport",
		"children":[
		{
			"name":"Rab GTPases and associated proteins",
			"children":[
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YML001W YPT7; Rab family GTPase YPT7\tK07897 RAB7A; Ras-related protein Rab-7A [EC:3.6.5.2]"
				}
				]
			},
			{
				"name":"Retromer subcomplex",
				"children":[
				{
					"name":"YJL154C VPS35; retromer subunit VPS35\tK18468 VPS35; vacuolar protein sorting-associated protein 35"
				},
				{
					"name":"YHR012W VPS29; retromer subunit VPS29\tK18467 VPS29; vacuolar protein sorting-associated protein 29"
				},
				{
					"name":"YJL053W PEP8; retromer subunit PEP8\tK18466 VPS26A_B; vacuolar protein sorting-associated protein 26A\/B"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YDR372C VPS74; Vps74p\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"YGR100W MDR1; GTPase-activating protein MDR1\tK19951 TBC1D8_9; TBC1 domain family member 8\/9"
				},
				{
					"name":"YJR134C SGM1; Sgm1p\tK20286 TMF1; TATA element modulatory factor"
				},
				{
					"name":"YPL174C NIP100; Nip100p\tK04648 DCTN1; dynactin 1"
				},
				{
					"name":"YLL040C VPS13; membrane morphogenesis protein VPS13\tK19525 VPS13A_C; vacuolar protein sorting-associated protein 13A\/C"
				}
				]
			}
			]
		},
		{
			"name":"Arf GTPases and associated proteins",
			"children":[
			{
				"name":"Arf GTPases",
				"children":[
				{
					"name":"YDL137W ARF2; Arf family GTPase ARF2\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"YDL192W ARF1; Arf family GTPase ARF1\tK07937 ARF1_2; ADP-ribosylation factor 1\/2"
				},
				{
					"name":"YBR164C ARL1; Arf family GTPase ARL1\tK07942 ARL1; ADP-ribosylation factor-like protein 1"
				},
				{
					"name":"YPL051W ARL3; Arf family GTPase ARL3\tK07952 ARFRP1; ADP-ribosylation factor related protein 1"
				}
				]
			},
			{
				"name":"Arf GTPase associated proteins",
				"children":[
				{
					"name":"YDL226C GCS1; GTPase-activating protein GCS1\tK12492 ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1"
				},
				{
					"name":"YER122C GLO3; ADP-ribosylation factor GTPase-activating protein\tK12493 ARFGAP2_3; ADP-ribosylation factor GTPase-activating protein 2\/3"
				},
				{
					"name":"YGL181W GTS1; Gts1p\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"YIL044C AGE2; GTPase-activating protein AGE2\tK12486 SMAP; stromal membrane-associated protein"
				},
				{
					"name":"YDR524C AGE1; GTPase-activating protein AGE1\tK12488 ASAP; Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein"
				},
				{
					"name":"YDR170C SEC7; Arf family guanine nucleotide exchange factor SEC7\tK18442 ARFGEF; brefeldin A-inhibited guanine nucleotide-exchange protein"
				},
				{
					"name":"YEL022W GEA2; Arf family guanine nucleotide exchange factor GEA2\tK18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1"
				},
				{
					"name":"YJR031C GEA1; Arf family guanine nucleotide exchange factor GEA1\tK18443 GBF1; golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1"
				}
				]
			}
			]
		},
		{
			"name":"Tethering complex",
			"children":[
			{
				"name":"Conserved oligomeric Golgi (COG) complex",
				"children":[
				{
					"name":"YER157W COG3; Golgi transport complex subunit COG3\tK20290 COG3; conserved oligomeric Golgi complex subunit 3"
				},
				{
					"name":"YPR105C COG4; Golgi transport complex subunit COG4\tK20291 COG4; conserved oligomeric Golgi complex subunit 4"
				},
				{
					"name":"YNL041C COG6; Golgi transport complex subunit COG6\tK20293 COG6; conserved oligomeric Golgi complex subunit 6"
				},
				{
					"name":"YML071C COG8; Golgi transport complex subunit COG8\tK20295 COG8; conserved oligomeric Golgi complex subunit 8"
				}
				]
			},
			{
				"name":"GARP complex",
				"children":[
				{
					"name":"YKR020W VPS51; Vps51p\tK20297 VPS51; vacuolar protein sorting-associated protein 51"
				},
				{
					"name":"YDR484W VPS52; Vps52p\tK20298 VPS52; vacuolar protein sorting-associated protein 52"
				},
				{
					"name":"YJL029C VPS53; Vps53p\tK20299 VPS53; vacuolar protein sorting-associated protein 53"
				},
				{
					"name":"YDR027C VPS54; Vps54p\tK17600 VPS54; vacuolar protein sorting-associated protein 54"
				}
				]
			},
			{
				"name":"TRAPP complex II",
				"children":[
				{
					"name":"YML077W BET5; TRAPP subunit BET5\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"YBR254C TRS20; TRAPP subunit TRS20\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"YKR068C BET3; TRAPP complex core subunit BET3\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"YDR246W TRS23; TRAPP subunit TRS23\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"YDR472W TRS31; TRAPP subunit TRS31\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"YOR115C TRS33; Trs33p\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				},
				{
					"name":"YDR108W TRS85; Trs85p\tK20305 TRAPPC8; trafficking protein particle complex subunit 8"
				},
				{
					"name":"YDR407C TRS120; Trs120p\tK20306 TRAPPC9; trafficking protein particle complex subunit 9"
				},
				{
					"name":"YMR218C TRS130; transport protein particle complex II subunit TRS130\tK20307 TRAPPC10; trafficking protein particle complex subunit 10"
				},
				{
					"name":"YGR166W TRS65; Trs65p\tK20311 TRS65; trafficking protein particle complex II-specific subunit 65"
				},
				{
					"name":"YEL048C TCA17; Tca17p\tK20312 TCA17; TRAPP-associated protein TCA17"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"AP-1 complex",
				"children":[
				{
					"name":"YPR029C APL4; Apl4p\tK12391 AP1G1; AP-1 complex subunit gamma-1"
				},
				{
					"name":"YKL135C APL2; Apl2p\tK12392 AP1B1; AP-1 complex subunit beta-1"
				},
				{
					"name":"YPL259C APM1; Apm1p\tK12393 AP1M; AP-1 complex subunit mu"
				},
				{
					"name":"YLR170C APS1; Aps1p\tK12394 AP1S1_2; AP-1 complex subunit sigma 1\/2"
				}
				]
			},
			{
				"name":"AP-3 complex",
				"children":[
				{
					"name":"YPL195W APL5; Apl5p\tK12396 AP3D; AP-3 complex subunit delta"
				},
				{
					"name":"YGR261C APL6; Apl6p\tK12397 AP3B; AP-3 complex subunit beta"
				},
				{
					"name":"YBR288C APM3; Apm3p\tK12398 AP3M; AP-3 complex subunit mu"
				},
				{
					"name":"YJL024C APS3; Aps3p\tK12399 AP3S; AP-3 complex subunit sigma"
				}
				]
			},
			{
				"name":"AP-4 complex"
			},
			{
				"name":"GGA",
				"children":[
				{
					"name":"YDR358W GGA1; ubiquitin-binding protein\tK12404 GGA; ADP-ribosylation factor-binding protein GGA"
				},
				{
					"name":"YHR108W GGA2; phosphatidylinositol 4-phosphate-binding protein\tK12404 GGA; ADP-ribosylation factor-binding protein GGA"
				}
				]
			},
			{
				"name":"Aftiphilin\/p200\/gamma-synergin complex",
				"children":[
				{
					"name":"YJL207C LAA1; Laa1p\tK24814 HEATR5; HEAT repeat-containing protein 5"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YKR031C SPO14; phospholipase D\tK01115 PLD1_2; phospholipase D1\/2 [EC:3.1.4.4]"
				},
				{
					"name":"YLR305C STT4; 1-phosphatidylinositol 4-kinase STT4\tK00888 PI4KA; phosphatidylinositol 4-kinase A [EC:2.7.1.67]"
				},
				{
					"name":"YDR208W MSS4; 1-phosphatidylinositol-4-phosphate 5-kinase\tK00889 PIP5K; 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68]"
				},
				{
					"name":"YFR019W FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase\tK00921 PIKFYVE; 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150]"
				},
				{
					"name":"YJL004C SYS1; Sys1p\tK20318 SYS1; protein SYS1"
				},
				{
					"name":"YBR187W GDT1; putative ribosome biosynthesis protein GDT1\tK23541 TMEM165; Ca2+\/H+ antiporter, TMEM165\/GDT1 family"
				},
				{
					"name":"YKL119C VPH2; Vph2p\tK23542 TMEM199; TMEM199 family protein"
				},
				{
					"name":"YHR060W VMA22; Vma22p\tK23543 CCDC115; coiled-coil domain-containing protein 115"
				},
				{
					"name":"YDR105C TMS1; Tms1p\tK23544 SERINC1; serine incorporator 1"
				},
				{
					"name":"YOR357C SNX3; Snx3p\tK17918 SNX3_12; sorting nexin-3\/12"
				},
				{
					"name":"YMR004W MVP1; Mvp1p\tK17922 SNX8; sorting nexin-8"
				},
				{
					"name":"YNL297C MON2; Mon2p\tK26678 MON2; protein MON2"
				},
				{
					"name":"YDR141C DOP1; Dop1p\tK26680 DOP1; protein dopey"
				},
				{
					"name":"YLR436C ECM30; Ecm30p\tK27894 HID1; protein HID1"
				},
				{
					"name":"YDR100W TVP15; Tvp15p\tK26750 TVP15; golgi apparatus membrane protein TVP15"
				},
				{
					"name":"YMR071C TVP18; Tvp18p\tK26751 TVP18; golgi apparatus membrane protein TVP18"
				},
				{
					"name":"YDR084C TVP23; Tvp23p\tK26752 TVP23; golgi apparatus membrane protein TVP23"
				},
				{
					"name":"YKR088C TVP38; Tvp38p\tK26753 TVP38; golgi apparatus membrane protein TVP38"
				},
				{
					"name":"YKR001C VPS1; dynamin-like GTPase VPS1\tK23481 VPS1; vacuolar protein sorting-associated protein 1"
				},
				{
					"name":"YBL017C PEP1; type I sorting receptor\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"YIL173W VTH1; signal sequence-binding protein\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"YJL222W VTH2; signal sequence-binding protein\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"YNR065C uncharacterized protein\tK28985 PEP1; vacuolar protein sorting\/targeting protein 10"
				},
				{
					"name":"YOR132W VPS17; retromer subunit VPS17\tK28986 VPS17; vacuolar protein sorting-associated protein 17"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Endoplasmic reticulum (ER) - Golgi transport",
		"children":[
		{
			"name":"Forward pathways",
			"children":[
			{
				"name":"Coat protein complex II (COP-II)",
				"children":[
				{
					"name":"YPL218W SAR1; Arf family GTPase SAR1\tK07953 SAR1; GTP-binding protein SAR1 [EC:3.6.5.-]"
				},
				{
					"name":"YLR208W SEC13; GTPase-activating protein SEC13\tK14004 SEC13; protein transport protein SEC13"
				},
				{
					"name":"YDL195W SEC31; Sec31p\tK14005 SEC31; protein transport protein SEC31"
				},
				{
					"name":"YPR181C SEC23; GTPase-activating protein SEC23\tK14006 SEC23; protein transport protein SEC23"
				},
				{
					"name":"YHR098C SFB3; Sfb3p\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"YIL109C SEC24; COPII subunit SEC24\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"YNL049C SFB2; COPII subunit SFB2\tK14007 SEC24; protein transport protein SEC24"
				},
				{
					"name":"YCR067C SED4; GTPase-activating protein SED4\tK14003 PREB; prolactin regulatory element-binding protein"
				},
				{
					"name":"YNR026C SEC12; Sar family guanine nucleotide exchange factor SEC12\tK14003 PREB; prolactin regulatory element-binding protein"
				},
				{
					"name":"YPL085W SEC16; Sec16p\tK20353 SEC16; COPII coat assembly protein SEC16"
				}
				]
			},
			{
				"name":"TRAPP complex I",
				"children":[
				{
					"name":"YML077W BET5; TRAPP subunit BET5\tK20300 TRAPPC1; trafficking protein particle complex subunit 1"
				},
				{
					"name":"YBR254C TRS20; TRAPP subunit TRS20\tK20301 TRAPPC2; trafficking protein particle complex subunit 2"
				},
				{
					"name":"YKR068C BET3; TRAPP complex core subunit BET3\tK20302 TRAPPC3; trafficking protein particle complex subunit 3"
				},
				{
					"name":"YDR246W TRS23; TRAPP subunit TRS23\tK20303 TRAPPC4; trafficking protein particle complex subunit 4"
				},
				{
					"name":"YDR472W TRS31; TRAPP subunit TRS31\tK20280 TRAPPC5; trafficking protein particle complex subunit 5"
				},
				{
					"name":"YOR115C TRS33; Trs33p\tK20304 TRAPPC6; trafficking protein particle complex subunit 6"
				}
				]
			},
			{
				"name":"p24 family proteins",
				"children":[
				{
					"name":"YAR002C-A ERP1; Erp1p\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"YGL002W ERP6; Erp6p\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"YHR110W ERP5; Erp5p\tK20346 TMED4_9_11; p24 family protein alpha"
				},
				{
					"name":"YGL200C EMP24; Emp24p\tK20347 TMED2; p24 family protein beta-1"
				},
				{
					"name":"YAL007C ERP2; Erp2p\tK14825 TMED5; p24 family protein gamma-2"
				},
				{
					"name":"YOR016C ERP4; Erp4p\tK14825 TMED5; p24 family protein gamma-2"
				},
				{
					"name":"YML012W ERV25; Erv25p\tK20352 TMED10; p24 family protein delta-1"
				}
				]
			},
			{
				"name":"PDI family proteins",
				"children":[
				{
					"name":"YCL043C PDI1; protein disulfide isomerase PDI1\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
				},
				{
					"name":"YDR518W EUG1; protein disulfide isomerase EUG1\tK09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]"
				},
				{
					"name":"YOR288C MPD1; protein disulfide isomerase MPD1\tK09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]"
				}
				]
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YFL038C YPT1; Rab family GTPase YPT1\tK07874 RAB1A; Ras-related protein Rab-1A"
				}
				]
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YNL044W YIP3; Yip3p\tK20359 RABAC1; PRA1 family protein 1"
				},
				{
					"name":"YFL027C GYP8; GTPase-activating protein GYP8\tK20372 TBC1D20; TBC1 domain family member 20"
				},
				{
					"name":"YOR070C GYP1; GTPase-activating protein GYP1\tK20360 TBC1D22; TBC1 domain family member 2"
				},
				{
					"name":"YNL263C YIF1; protein transporter YIF1\tK20362 YIF1; protein transport protein YIF1"
				},
				{
					"name":"YER074W-A YOS1; Yos1p\tK22939 IER3IP1; immediate early response 3-interacting protein 1"
				},
				{
					"name":"YDL058W USO1; Uso1p\tK20361 USO1; intracellular protein transport protein USO1"
				}
				]
			},
			{
				"name":"ER-Golgi intermediate compartment (ERGIC) proteins",
				"children":[
				{
					"name":"YFL048C EMP47; Emp47p\tK10080 LMAN1; lectin, mannose-binding 1"
				},
				{
					"name":"YLR080W EMP46; Emp46p\tK10080 LMAN1; lectin, mannose-binding 1"
				},
				{
					"name":"YLR057W MNL2; putative mannosidase MNL2\tK01230 MAN1A_C; mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113]"
				},
				{
					"name":"YJR131W MNS1; mannosyl-oligosaccharide 1,2-alpha-mannosidase\tK23741 MAN1B; endoplasmic reticulum Man9GlcNAc2 1,2-alpha-mannosidase [EC:3.2.1.209]"
				},
				{
					"name":"YML067C ERV41; Erv41p\tK20366 ERGIC2; endoplasmic reticulum-Golgi intermediate compartment protein 2"
				},
				{
					"name":"YAL042W ERV46; Erv46p\tK20367 ERGIC3; endoplasmic reticulum-Golgi intermediate compartment protein 3"
				},
				{
					"name":"YBR210W ERV15; Erv15p\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"YGL054C ERV14; cornichon family protein\tK20368 CNIH; protein cornichon"
				},
				{
					"name":"YGR284C ERV29; Erv29p\tK20369 ERV29; ER-derived vesicles protein"
				},
				{
					"name":"YJL034W KAR2; Hsp70 family ATPase KAR2\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"YCL001W RER1; protein retrieval receptor\tK29081 RER1; Rer1 family protein"
				}
				]
			}
			]
		},
		{
			"name":"Retrieval pathways",
			"children":[
			{
				"name":"Coat protein complex I (COP-I)",
				"children":[
				{
					"name":"YDL145C COP1; coatomer subunit alpha\tK05236 COPA; coatomer subunit alpha"
				},
				{
					"name":"YDR238C SEC26; coatomer subunit beta\tK17301 COPB1; coatomer subunit beta"
				},
				{
					"name":"YGL137W SEC27; coatomer subunit beta'\tK17302 COPB2; coatomer subunit beta'"
				},
				{
					"name":"YNL287W SEC21; coatomer subunit gamma\tK17267 COPG; coatomer subunit gamma"
				},
				{
					"name":"YFR051C RET2; coatomer subunit delta\tK20471 COPD; coatomer subunit delta"
				},
				{
					"name":"YIL076W SEC28; coatomer subunit epsilon\tK17268 COPE; coatomer subunit epsilon"
				},
				{
					"name":"YPL010W RET3; coatomer subunit zeta\tK20472 COPZ; coatomer subunit zeta"
				}
				]
			},
			{
				"name":"NRZ (DSL1) complex",
				"children":[
				{
					"name":"YGL145W TIP20; Tip20p\tK20474 RINT1; RAD50-interacting protein 1"
				},
				{
					"name":"YNL258C DSL1; Dsl1p\tK11578 ZW10; protein transport protein DSL1\/ZW10"
				},
				{
					"name":"YLR440C SEC39; Sec39p\tK20475 SEC39; protein transport protein SEC39"
				}
				]
			},
			{
				"name":"Golgi to ER traffic proteins (GET)",
				"children":[
				{
					"name":"YGL020C GET1; GET complex subunit GET1\tK22384 GET1; tail-anchored protein insertion receptor"
				},
				{
					"name":"YER083C GET2; GET complex subunit GET2\tK22386 GET2; GET complex subunit GET2"
				},
				{
					"name":"YDL100C GET3; guanine nucleotide exchange factor GET3\tK01551 arsA; arsenite\/tail-anchored protein-transporting ATPase [EC:7.3.2.7 7.3.-.-]"
				},
				{
					"name":"YOR164C GET4; Get4p\tK23387 GET4; golgi to ER traffic protein 4"
				},
				{
					"name":"YOL111C MDY2; Mdy2p\tK23388 UBL4; ubiquitin-like protein 4"
				}
				]
			},
			{
				"name":"Rab GTPases"
			},
			{
				"name":"Rab associated proteins",
				"children":[
				{
					"name":"YLR039C RIC1; Ric1p\tK20476 RIC1; RAB6A-GEF complex partner protein 1"
				},
				{
					"name":"YDR137W RGP1; Rgp1p\tK20477 RGP1; RAB6A-GEF complex partner protein 2"
				},
				{
					"name":"YBL040C ERD2; Erd2p\tK10949 KDELR; ER lumen protein retaining receptor"
				},
				{
					"name":"YDR323C PEP7; phosphatidylinositol-3-phosphate binding protein\tK12481 RBSN; rabenosyn-5"
				},
				{
					"name":"YOR070C GYP1; GTPase-activating protein GYP1\tK20360 TBC1D22; TBC1 domain family member 2"
				}
				]
			}
			]
		},
		{
			"name":"Others",
			"children":[
			{
				"name":"Oxysterol-binding proteins",
				"children":[
				{
					"name":"YAR042W SWH1; oxysterol-binding protein related protein SWH1\tK20456 OSBP; oxysterol-binding protein 1"
				},
				{
					"name":"YDL019C OSH2; oxysterol-binding protein related protein OSH2\tK20456 OSBP; oxysterol-binding protein 1"
				},
				{
					"name":"YHR073W OSH3; oxysterol-binding protein related protein OSH3\tK20463 OSBPL3_6_7; oxysterol-binding protein-related protein 3\/6\/7"
				},
				{
					"name":"YHR001W OSH7; oxysterol-binding protein related protein OSH7\tK22285 OSBPL8; oxysterol-binding protein-related protein 8"
				},
				{
					"name":"YKR003W OSH6; oxysterol-binding protein OSH6\tK22285 OSBPL8; oxysterol-binding protein-related protein 8"
				},
				{
					"name":"YOR237W HES1; oxysterol-binding protein related protein HES1\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				},
				{
					"name":"YPL145C KES1; oxysterol-binding protein KES1\tK20465 OSBPL9_10_11; oxysterol-binding protein-related protein 9\/10\/11"
				}
				]
			},
			{
				"name":"FXYD proteins"
			},
			{
				"name":"YIPF proteins",
				"children":[
				{
					"name":"YGL161C YIP5; Yip5p\tK22940 YIPF1_2; protein YIPF1\/2"
				},
				{
					"name":"YGR172C YIP1; transporter YIP1\tK20363 YIPF5_7; protein YIPF5\/7"
				},
				{
					"name":"YGL198W YIP4; Yip4p\tK22943 YIPF6; protein YIPF6"
				}
				]
			},
			{
				"name":"ER membrane protein complex",
				"children":[
				{
					"name":"YCL045C EMC1; Emc1p\tK23562 EMC1; ER membrane protein complex subunit 1"
				},
				{
					"name":"YJR088C EMC2; Emc2p\tK23563 EMC2; ER membrane protein complex subunit 2"
				},
				{
					"name":"YKL207W EMC3; Emc3p\tK23564 EMC3; ER membrane protein complex subunit 3"
				},
				{
					"name":"YGL231C EMC4; chaperone EMC4\tK23565 EMC4; ER membrane protein complex subunit 4"
				},
				{
					"name":"YIL027C EMC5; Emc5p\tK23566 MMGT1; membrane magnesium transporter 1"
				},
				{
					"name":"YLL014W EMC6; Emc6p\tK23567 EMC6; ER membrane protein complex subunit 6"
				}
				]
			},
			{
				"name":"SEC61 complex",
				"children":[
				{
					"name":"YBR283C SSH1; Ssh1p\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"YLR378C SEC61; translocon subunit SEC61\tK10956 SEC61A; protein transport protein SEC61 subunit alpha"
				},
				{
					"name":"YER019C-A SBH2; Arf family guanine nucleotide exchange factor SBH2\tK09481 SEC61B; protein transport protein SEC61 subunit beta"
				},
				{
					"name":"YER087C-B SBH1; Arf family guanine nucleotide exchange factor SBH1\tK09481 SEC61B; protein transport protein SEC61 subunit beta"
				},
				{
					"name":"YDR086C SSS1; translocon subunit SSS1\tK07342 SEC61G; protein transport protein SEC61 subunit gamma and related proteins"
				}
				]
			},
			{
				"name":"TRAP complex"
			},
			{
				"name":"Multi-pass translocon (MPT) complex",
				"children":[
				{
					"name":"YNR021W uncharacterized protein\tK24962 CCDC47; PAT complex subunit CCDC47"
				}
				]
			},
			{
				"name":"Post-GPI attachment to proteins factors (PGAP)",
				"children":[
				{
					"name":"YFL025C BST1; Bst1p\tK05294 PGAP1; GPI inositol-deacylase [EC:3.-.-.-]"
				},
				{
					"name":"YCR044C PER1; Per1p\tK23553 PGAP3; post-GPI attachment to proteins factor 3"
				},
				{
					"name":"YDR182W CDC1; putative lipid phosphatase CDC1\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				},
				{
					"name":"YIL039W TED1; Ted1p\tK23362 MPPE1; ethanolamine phosphate phosphodiesterase [EC:3.1.-.-]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YDR189W SLY1; syntaxin-binding protein\tK19998 SCFD1; sec1 family domain-containing protein 1"
				},
				{
					"name":"YLL023C POM33; nucleoporin POM33\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"YLR064W PER33; Per33p\tK20724 TMEM33; transmembrane protein 33"
				},
				{
					"name":"YLR242C ARV1; sterol homeostasis protein ARV1\tK21848 ARV1; lipid intermediate transporter"
				},
				{
					"name":"YFR042W KEG1; Keg1p\tK21849 KEG1; beta-1,6-glucan synthesis-associated protein KEG1"
				},
				{
					"name":"YGR143W SKN1; beta-glucan synthesis-associated protein SKN1\tK21850 KRE6; beta-glucan synthesis-associated protein KRE6"
				},
				{
					"name":"YPR159W KRE6; beta-glucan synthesis-associated protein KRE6\tK21850 KRE6; beta-glucan synthesis-associated protein KRE6"
				},
				{
					"name":"YDR372C VPS74; Vps74p\tK15620 GOLPH3; golgi phosphoprotein 3"
				},
				{
					"name":"YHR192W LNP1; Lnp1p\tK23292 LNPK; endoplasmic reticulum junction formation protein lunapark"
				},
				{
					"name":"YHR133C NSG1; Nsg1p\tK26681 INSIG; insulin-induced protein"
				},
				{
					"name":"YNL156C NSG2; Nsg2p\tK26681 INSIG; insulin-induced protein"
				},
				{
					"name":"YMR292W GOT1; Got1p\tK26683 GOLT1; vesicle transport protein GOT1"
				},
				{
					"name":"YOR165W SEY1; dynamin-like GTPase SEY1\tK22698 SEY1; protein SEY1 [EC:3.6.5.-]"
				},
				{
					"name":"YPR091C NVJ2; Nvj2p\tK29087 NVJ2; nucleus-vacuole junction protein 2"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Autophagy",
		"children":[
		{
			"name":"Autophagosome formation proteins",
			"children":[
			{
				"name":"ULK complex",
				"children":[
				{
					"name":"YPR185W ATG13; serine\/threonine protein kinase regulatory subunit ATG13\tK08331 ATG13; autophagy-related protein 13"
				}
				]
			},
			{
				"name":"Atg1 complex",
				"children":[
				{
					"name":"YGL180W ATG1; serine\/threonine protein kinase ATG1\tK08269 ULK2; serine\/threonine-protein kinase ULK2 [EC:2.7.11.1]"
				},
				{
					"name":"YPR185W ATG13; serine\/threonine protein kinase regulatory subunit ATG13\tK08331 ATG13; autophagy-related protein 13"
				},
				{
					"name":"YLR423C ATG17; protein kinase regulatory subunit ATG17\tK08329 ATG17; autophagy-related protein 17"
				},
				{
					"name":"YPL166W ATG29; Atg29p\tK21143 ATG29; autophagy-related protein 29"
				},
				{
					"name":"YDR022C ATG31; Atg31p\tK21144 ATG31; autophagy-related protein 31"
				}
				]
			},
			{
				"name":"PI3K complex",
				"children":[
				{
					"name":"YLR240W VPS34; phosphatidylinositol 3-kinase VPS34\tK00914 PIK3C3; phosphatidylinositol 3-kinase [EC:2.7.1.137]"
				},
				{
					"name":"YBR097W VPS15; ubiquitin-binding serine\/threonine protein kinase VPS15\tK08333 PIK3R4; phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1]"
				},
				{
					"name":"YBR128C ATG14; Atg14p\tK08335 ATG14; autophagy-related protein 14"
				},
				{
					"name":"YPL120W VPS30; beclin 1\tK08334 BECN; beclin"
				},
				{
					"name":"YLR211C ATG38; Atg38p\tK21145 ATG38; autophagy-related protein 38"
				}
				]
			},
			{
				"name":"ATG9 transmembrane protein",
				"children":[
				{
					"name":"YDL149W ATG9; autophagy protein ATG9\tK17907 ATG9; autophagy-related protein 9"
				}
				]
			},
			{
				"name":"Atg18-Atg2 complex",
				"children":[
				{
					"name":"YFR021W ATG18; phosphoinositide binding protein ATG18\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"YPL100W ATG21; Atg21p\tK17908 WIPI1_2; autophagy-related protein 18"
				},
				{
					"name":"YNL242W ATG2; Atg2p\tK17906 ATG2; autophagy-related protein 2"
				}
				]
			},
			{
				"name":"Atg12 conjugation proteins",
				"children":[
				{
					"name":"YBR217W ATG12; Atg12p\tK08336 ATG12; ubiquitin-like protein ATG12"
				},
				{
					"name":"YHR171W ATG7; Atg7p\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"YLL042C ATG10; E2-like conjugating enzyme\tK08338 ATG10; ubiquitin-like-conjugating enzyme ATG10"
				},
				{
					"name":"YPL149W ATG5; Atg5p\tK08339 ATG5; autophagy-related protein 5"
				},
				{
					"name":"YMR159C ATG16; Atg16p\tK08340 ATG16; autophagy-related protein 16"
				}
				]
			},
			{
				"name":"Atg8 conjugation proteins",
				"children":[
				{
					"name":"YBL078C ATG8; ubiquitin-like protein ATG8\tK08341 GABARAP; GABA(A) receptor-associated protein"
				},
				{
					"name":"YNL223W ATG4; cysteine protease ATG4\tK08342 ATG4; cysteine protease ATG4 [EC:3.4.22.-]"
				},
				{
					"name":"YHR171W ATG7; Atg7p\tK08337 ATG7; ubiquitin-like modifier-activating enzyme ATG7"
				},
				{
					"name":"YNR007C ATG3; Atg3p\tK08343 ATG3; ubiquitin-like-conjugating enzyme ATG3"
				}
				]
			}
			]
		},
		{
			"name":"Cytoplasm to vacuolar targeting (CVT) pathway",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"YKL103C APE1; metalloaminopeptidase APE1\tK01268 LAP4; aminopeptidase I [EC:3.4.11.22]"
				},
				{
					"name":"YGL156W AMS1; alpha-mannosidase\tK01191 MAN2C1; alpha-mannosidase [EC:3.2.1.24]"
				},
				{
					"name":"YHR113W APE4; aspartyl aminopeptidase\tK01267 DNPEP; aspartyl aminopeptidase [EC:3.4.11.21]"
				}
				]
			},
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"YOL082W ATG19; Atg19p\tK21997 ATG19_34; autophagy-related protein 19\/34"
				},
				{
					"name":"YOL083W ATG34; Atg34p\tK21997 ATG19_34; autophagy-related protein 19\/34"
				}
				]
			},
			{
				"name":"Scaffold protein",
				"children":[
				{
					"name":"YPR049C ATG11; autophagy protein ATG11\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"Other Cvt associated proteins",
				"children":[
				{
					"name":"YDL113C ATG20; Atg20p\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"YDR425W SNX41; Snx41p\tK21996 SNX41_42; sorting nexin-41\/42"
				},
				{
					"name":"YJL036W SNX4; Snx4p\tK17919 SNX4; sorting nexin-4"
				},
				{
					"name":"YCR068W ATG15; triglyceride lipase ATG15\tK17900 ATG15; lipase ATG15 [EC:3.1.1.3]"
				},
				{
					"name":"YLR431C ATG23; Atg23p\tK17909 ATG23; autophagy-related protein 23"
				},
				{
					"name":"YJL178C ATG27; Atg27p\tK21141 ATG27; autophagy-related protein 27"
				},
				{
					"name":"YEL013W VAC8; protein anchor VAC8\tK08332 VAC8; vacuolar protein 8"
				}
				]
			}
			]
		},
		{
			"name":"Mitophagy",
			"children":[
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"YIL146C ATG32; mitophagy protein ATG32\tK17984 ATG32; autophagy-related protein 32"
				}
				]
			},
			{
				"name":"Scaffold proteins",
				"children":[
				{
					"name":"YPR049C ATG11; autophagy protein ATG11\tK08330 ATG11; autophagy-related protein 11"
				}
				]
			},
			{
				"name":"PINK1-Parkin associated proteins",
				"children":[
				{
					"name":"YBR179C FZO1; mitofusin\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"Other mitophagy associated  proteins",
				"children":[
				{
					"name":"YCL040W GLK1; glucokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"YDR516C EMI2; putative glucokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"YFR053C HXK1; hexokinase 1\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"YGL253W HXK2; hexokinase 2\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"YLR446W NGK1; hexokinase\tK00844 HK; hexokinase [EC:2.7.1.1]"
				},
				{
					"name":"YDL130W-A STF1; ATPase-binding protein\tK22255 ATPIF1; ATPase inhibitor, mitochondrial"
				},
				{
					"name":"YDL181W INH1; ATPase inhibitor\tK22255 ATPIF1; ATPase inhibitor, mitochondrial"
				},
				{
					"name":"YNL070W TOM7; Tom7p\tK17771 TOM7; mitochondrial import receptor subunit TOM7"
				},
				{
					"name":"YLR356W ATG33; Atg33p\tK19717 ATG33; autophagy-related protein 33"
				}
				]
			}
			]
		},
		{
			"name":"Pexophagy",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"YDR329C PEX3; Pex3p\tK13336 PEX3; peroxin-3"
				},
				{
					"name":"YGL153W PEX14; Pex14p\tK13343 PEX14; peroxin-14"
				}
				]
			},
			{
				"name":"Cargo receptors",
				"children":[
				{
					"name":"YJL185C ATG36; Atg36p\tK22258 ATG36; autophagy-related protein 36"
				}
				]
			},
			{
				"name":"Other pexophagy associated proteins",
				"children":[
				{
					"name":"YKL197C PEX1; AAA family ATPase peroxin 1\tK13338 PEX1; peroxin-1 [EC:3.6.4.-]"
				},
				{
					"name":"YNL329C PEX6; AAA family ATPase peroxin 6\tK13339 PEX6; peroxin-6 [EC:3.6.4.-]"
				},
				{
					"name":"YOL044W PEX15; Pex15p\tK22260 PEX15; peroxin-15"
				}
				]
			}
			]
		},
		{
			"name":"Aggrephagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Scaffold proteins"
			},
			{
				"name":"Other aggrephagy associated proteins",
				"children":[
				{
					"name":"YDL126C CDC48; AAA family ATPase CDC48\tK13525 VCP; transitional endoplasmic reticulum ATPase"
				},
				{
					"name":"YNL021W HDA1; histone deacetylase HDA1\tK11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]"
				}
				]
			}
			]
		},
		{
			"name":"Xenophagy",
			"children":[
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Other xenophagy associated proteins"
			}
			]
		},
		{
			"name":"ER-phagy",
			"children":[
			{
				"name":"ER-phagy recepters",
				"children":[
				{
					"name":"YPL094C SEC62; Sec63 complex subunit SEC62\tK12275 SEC62; translocation protein SEC62"
				},
				{
					"name":"YOR152C ATG40; Atg40p\tK28118 ATG40; autophagy-related protein 40"
				},
				{
					"name":"YLR312C ATG39; Atg39p\tK28119 ATG39; autophagy-related protein 39"
				}
				]
			},
			{
				"name":"Other ER-phagy associated proteins",
				"children":[
				{
					"name":"YAL058W CNE1; calnexin\tK08054 CANX; calnexin"
				},
				{
					"name":"YPL170W DAP1; Dap1p\tK17278 PGRMC1_2; membrane-associated progesterone receptor component"
				}
				]
			},
			{
				"name":"ER stress-related proteins",
				"children":[
				{
					"name":"YJL034W KAR2; Hsp70 family ATPase KAR2\tK09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:5.6.1.10]"
				},
				{
					"name":"YJR007W SUI2; translation initiation factor eIF2 subunit alpha\tK03237 EIF2S1; translation initiation factor 2 subunit 1"
				},
				{
					"name":"YDL072C YET3; Yet3p\tK14009 BCAP31; B-cell receptor-associated protein 31"
				}
				]
			}
			]
		},
		{
			"name":"Chaperone mediated autophagy (CMA)",
			"children":[
			{
				"name":"Selective cargos",
				"children":[
				{
					"name":"YLR027C AAT2; aspartate transaminase AAT2\tK14454 GOT1; aspartate aminotransferase, cytoplasmic [EC:2.6.1.1]"
				},
				{
					"name":"YGR192C TDH3; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"YJL052W TDH1; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"YJR009C TDH2; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2\tK00134 GAPDH; glyceraldehyde 3-phosphate dehydrogenase (phosphorylating) [EC:1.2.1.12]"
				},
				{
					"name":"YDL021W GPM2; phosphoglycerate mutase family protein GPM2\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"YKL152C GPM1; phosphoglycerate mutase GPM1\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"YOL056W GPM3; phosphoglycerate mutase family protein GPM3\tK01834 PGAM; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]"
				},
				{
					"name":"YAL038W CDC19; pyruvate kinase CDC19\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"YOR347C PYK2; pyruvate kinase PYK2\tK00873 PK; pyruvate kinase [EC:2.7.1.40]"
				},
				{
					"name":"YMR276W DSK2; ubiquitin domain-containing protein DSK2\tK04523 UBQLN; ubiquilin"
				}
				]
			},
			{
				"name":"Cargo receptors"
			},
			{
				"name":"Chaperones",
				"children":[
				{
					"name":"YAL005C SSA1; Hsp70 family ATPase SSA1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YBL075C SSA3; Hsp70 family ATPase SSA3\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YDL229W SSB1; Hsp70 family ATPase SSB1\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YER103W SSA4; Hsp70 family chaperone SSA4\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YLL024C SSA2; Hsp70 family chaperone SSA2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YNL209W SSB2; Hsp70 family ATPase SSB2\tK03283 HSPA1_6_8; heat shock 70kDa protein 1\/6\/8"
				},
				{
					"name":"YMR186W HSC82; Hsp90 family chaperone HSC82\tK04079 HSP90A; molecular chaperone HtpG"
				},
				{
					"name":"YPL240C HSP82; Hsp90 family chaperone HSP82\tK04079 HSP90A; molecular chaperone HtpG"
				}
				]
			},
			{
				"name":"Co-chaperones"
			},
			{
				"name":"Other CMA associated proteins",
				"children":[
				{
					"name":"YBR118W TEF2; translation elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"YPR080W TEF1; translation elongation factor EF-1 alpha\tK03231 EEF1A; elongation factor 1-alpha"
				},
				{
					"name":"YBR139W ATG42; carboxypeptidase C\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				},
				{
					"name":"YMR297W PRC1; carboxypeptidase C PRC1\tK13289 CTSA; cathepsin A (carboxypeptidase C) [EC:3.4.16.5]"
				}
				]
			}
			]
		},
		{
			"name":"Other autophagy associated proteins",
			"children":[
			{
				"name":"RNautophagy\/DNautophagy"
			},
			{
				"name":"Micronucleophagy",
				"children":[
				{
					"name":"YHR195W NVJ1; Nvj1p\tK22264 NVJ1; nucleus-vacuole junction protein 1"
				},
				{
					"name":"YEL013W VAC8; protein anchor VAC8\tK08332 VAC8; vacuolar protein 8"
				}
				]
			},
			{
				"name":"Midbophagy"
			},
			{
				"name":"Glycophagy"
			},
			{
				"name":"TRIM-directed selective autophagy"
			},
			{
				"name":"ER-mitochondria tethering complex",
				"children":[
				{
					"name":"YBR179C FZO1; mitofusin\tK06030 MFN2; mitofusin 2 [EC:3.6.5.-]"
				}
				]
			},
			{
				"name":"mTORC1 complex",
				"children":[
				{
					"name":"YJR066W TOR1; phosphatidylinositol kinase-related protein kinase TOR1\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"YKL203C TOR2; phosphatidylinositol kinase-related protein kinase TOR2\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"YNL006W LST8; TOR complex subunit LST8\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"YHR186C KOG1; ubiquitin-binding TORC1 subunit KOG1\tK07204 RAPTOR; regulatory associated protein of mTOR"
				},
				{
					"name":"YPL180W TCO89; Tco89p\tK25579 TCO89; target of rapamycin complex 1 subunit TCO89"
				}
				]
			},
			{
				"name":"mTORC2 complex",
				"children":[
				{
					"name":"YJR066W TOR1; phosphatidylinositol kinase-related protein kinase TOR1\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"YKL203C TOR2; phosphatidylinositol kinase-related protein kinase TOR2\tK07203 MTOR; serine\/threonine-protein kinase mTOR [EC:2.7.11.1]"
				},
				{
					"name":"YNL006W LST8; TOR complex subunit LST8\tK08266 MLST8; target of rapamycin complex subunit LST8"
				},
				{
					"name":"YOL078W AVO1; Avo1p\tK20410 MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1\/AVO1"
				},
				{
					"name":"YER093C TSC11; TORC2 complex subunit TSC11\tK08267 RICTOR; rapamycin-insensitive companion of mTOR"
				},
				{
					"name":"YMR068W AVO2; Avo2p\tK25576 AVO2; target of rapamycin complex 2 subunit AVO2"
				},
				{
					"name":"YBR270C BIT2; Bit2p\tK25577 BIT61_2; target of rapamycin complex 2 subunit BIT61\/BIT2"
				},
				{
					"name":"YJL058C BIT61; Bit61p\tK25577 BIT61_2; target of rapamycin complex 2 subunit BIT61\/BIT2"
				}
				]
			},
			{
				"name":"SEACIT\/GATOR1 complex",
				"children":[
				{
					"name":"YJR138W IML1; GTPase-activating protein IML1\tK20404 DEPDC5; SEA\/GATOR complex protein SEA1\/DEPDC5"
				},
				{
					"name":"YEL062W NPR2; nitrogen permease regulating protein NPR2\tK20405 NPRL2; nitrogen permease regulator 2"
				},
				{
					"name":"YHL023C NPR3; Npr3p\tK20406 NPRL3; nitrogen permease regulator 3"
				}
				]
			},
			{
				"name":"SEACAT\/GATOR2 complex",
				"children":[
				{
					"name":"YOL138C RTC1; Rtc1p\tK20408 WDR24; SEA\/GATOR complex protein SEA2\/WDR24"
				},
				{
					"name":"YDR128W MTC5; Mtc5p\tK20409 WDR59; SEA\/GATOR complex protein SEA3\/WDR59"
				},
				{
					"name":"YBL104C SEA4; Sea4p\tK20407 MIOS; SEA\/GATOR complex protein SEA4\/MIOS"
				},
				{
					"name":"YGL100W SEH1; Seh1p\tK14299 SEH1; nucleoporin SEH1"
				},
				{
					"name":"YLR208W SEC13; GTPase-activating protein SEC13\tK14004 SEC13; protein transport protein SEC13"
				}
				]
			},
			{
				"name":"KICSTOR complex"
			},
			{
				"name":"Rab GTPases",
				"children":[
				{
					"name":"YFL038C YPT1; Rab family GTPase YPT1\tK07874 RAB1A; Ras-related protein Rab-1A"
				},
				{
					"name":"YFL005W SEC4; Rab family GTPase SEC4\tK07901 RAB8A; Ras-related protein Rab-8A"
				}
				]
			},
			{
				"name":"Rab associated proteins"
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YDL134C PPH21; phosphoprotein phosphatase 2A catalytic subunit PPH21\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"YDL188C PPH22; phosphoprotein phosphatase 2A catalytic subunit PPH22\tK04382 PPP2C; serine\/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]"
				},
				{
					"name":"YMR028W TAP42; Tap42p\tK17606 IGBP1; immunoglobulin-binding protein 1"
				},
				{
					"name":"YCL038C ATG22; Atg22p\tK06902 UMF1; MFS transporter, UMF1 family"
				},
				{
					"name":"YKL146W AVT3; Avt3p\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"YNL101W AVT4; Avt4p\tK14209 SLC36A; solute carrier family 36 (proton-coupled amino acid transporter)"
				},
				{
					"name":"YGR223C HSV2; Hsv2p\tK22991 WDR45; WD repeat-containing protein 45"
				},
				{
					"name":"YGR105W VMA21; Vma21p\tK23952 VMA21; vacuolar ATPase assembly integral membrane protein VMA21"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Others",
		"children":[
		{
			"name":"NADPH oxidases (Nox) and associated proteins",
			"children":[
			{
				"name":"NADPH oxidases"
			},
			{
				"name":"Nox associated proteins"
			}
			]
		},
		{
			"name":"Actin-binding proteins",
			"children":[
			{
				"name":"Myosins",
				"children":[
				{
					"name":"YKL129C MYO3; myosin 3\tK10356 MYO1; myosin I"
				},
				{
					"name":"YMR109W MYO5; myosin 5\tK10356 MYO1; myosin I"
				},
				{
					"name":"YAL029C MYO4; myosin 4\tK10357 MYO5; myosin V"
				},
				{
					"name":"YOR326W MYO2; myosin 2\tK10357 MYO5; myosin V"
				}
				]
			},
			{
				"name":"Arp2\/3 complex",
				"children":[
				{
					"name":"YBR234C ARC40; Arc40p\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
				},
				{
					"name":"YNR035C ARC35; Arc35p\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
				},
				{
					"name":"YLR370C ARC18; Arc18p\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
				},
				{
					"name":"YKL013C ARC19; Arc19p\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
				},
				{
					"name":"YIL062C ARC15; Arc15p\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
				},
				{
					"name":"YDL029W ARP2; actin-related protein 2\tK17260 ACTR2; actin-related protein 2"
				},
				{
					"name":"YJR065C ARP3; actin-related protein 3\tK18584 ACTR3; actin-related protein 3"
				}
				]
			},
			{
				"name":"Nucleation-promoting factors (NPFs)",
				"children":[
				{
					"name":"YOR181W LAS17; actin-binding protein LAS17\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
				},
				{
					"name":"YCR088W ABP1; Abp1p\tK20520 DBNL; drebrin-like protein"
				},
				{
					"name":"YIR006C PAN1; Pan1p\tK20047 PAN1; actin cytoskeleton-regulatory complex protein PAN1"
				},
				{
					"name":"YDR388W RVS167; amphiphysin\tK12562 AMPH; amphiphysin"
				},
				{
					"name":"YBL007C SLA1; cytoskeletal protein-binding protein SLA1\tK20046 SLA1; actin cytoskeleton-regulatory complex protein SLA1"
				},
				{
					"name":"YJL020C BBC1; Bbc1p\tK20521 BBC1; myosin tail region-interacting protein MTI1"
				},
				{
					"name":"YGR136W LSB1; Lsb1p\tK20522 LSB1_2; LAS seventeen-binding protein 1\/2"
				},
				{
					"name":"YPR154W PIN3; Pin3p\tK20522 LSB1_2; LAS seventeen-binding protein 1\/2"
				},
				{
					"name":"YFR024C-A LSB3; Lsb3p\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				},
				{
					"name":"YHR016C YSC84; Ysc84p\tK20523 SH3YL1; SH3 domain-containing YSC84-like protein 1"
				},
				{
					"name":"YCL034W LSB5; Lsb5p\tK20524 LSB5; LAS seventeen-binding protein 5"
				},
				{
					"name":"YJL100W LSB6; 1-phosphatidylinositol 4-kinase LSB6\tK13711 PI4K2; phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67]"
				}
				]
			},
			{
				"name":"Others",
				"children":[
				{
					"name":"YOR122C PFY1; profilin\tK05759 PFN; profilin"
				},
				{
					"name":"YLL050C COF1; cofilin\tK05765 CFL; cofilin"
				},
				{
					"name":"YNL138W SRV2; adenylate cyclase-binding protein\tK17261 CAP1_2; adenylyl cyclase-associated protein"
				},
				{
					"name":"YKL079W SMY1; Smy1p\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
				},
				{
					"name":"YOR367W SCP1; Scp1p\tK20526 TAGLN; transgelin"
				}
				]
			}
			]
		},
		{
			"name":"Mucins",
			"children":[
			{
				"name":"Membrane bound mucins"
			},
			{
				"name":"Secretory mucins"
			}
			]
		},
		{
			"name":"MARVEL domain-containing proteins"
		},
		{
			"name":"Specific organelles associated proteins",
			"children":[
			{
				"name":"Melanosome"
			},
			{
				"name":"Auto phagosome"
			},
			{
				"name":"Lipid droplets",
				"children":[
				{
					"name":"YDR319C YFT2; Yft2p\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				},
				{
					"name":"YGL126W SCS3; Scs3p\tK28100 FITM2; fat storage-inducing transmembrane protein 2 [EC:3.6.1.-]"
				}
				]
			},
			{
				"name":"Mitochondrion"
			}
			]
		},
		{
			"name":"Rho GTPase associated proteins",
			"children":[
			{
				"name":"Rho GTPase-activating proteins",
				"children":[
				{
					"name":"YBR260C RGD1; GTPase-activating protein RGD1\tK20643 RGD1; Rho GTPase-activating protein RGD1"
				}
				]
			},
			{
				"name":"Rho guanine nucleotide exchange factors (GEFs)",
				"children":[
				{
					"name":"YLR422W DCK1; Dck1p\tK05727 DOCK3; dedicator of cytokinesis protein 3"
				},
				{
					"name":"YKL047W ANR2; Anr2p\tK28415 DENND11; DENN domain-containing protein 11"
				}
				]
			}
			]
		}
		]
	}
	]
}
