{
	"name":"sce04812",
	"children":[
	{
		"name":"Eukaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin filaments \/ Microfilaments",
			"children":[
			{
				"name":"Actins",
				"children":[
				{
					"name":"Actins",
					"children":[
					{
						"name":"YFL039C ACT1; actin\tK10355 ACTF; actin, other eukaryote"
					}
					]
				},
				{
					"name":"Actin-related proteins",
					"children":[
					{
						"name":"YHR129C ARP1; actin-related protein 1\tK16575 ACTR1; centractin"
					},
					{
						"name":"YLR085C ARP6; Arp6p\tK11662 ACTR6; actin-related protein 6"
					}
					]
				}
				]
			},
			{
				"name":"Actin-binding proteins",
				"children":[
				{
					"name":"Myosins",
					"children":[
					{
						"name":"YKL129C MYO3; myosin 3\tK10356 MYO1; myosin I"
					},
					{
						"name":"YMR109W MYO5; myosin 5\tK10356 MYO1; myosin I"
					},
					{
						"name":"YAL029C MYO4; myosin 4\tK10357 MYO5; myosin V"
					},
					{
						"name":"YOR326W MYO2; myosin 2\tK10357 MYO5; myosin V"
					},
					{
						"name":"YHR023W MYO1; myosin 1\tK10352 MYH9s; myosin heavy chain 9\/10\/11\/14"
					}
					]
				},
				{
					"name":"Arp2\/3 complex",
					"children":[
					{
						"name":"YBR234C ARC40; Arc40p\tK05757 ARPC1A_B; actin related protein 2\/3 complex, subunit 1A\/1B"
					},
					{
						"name":"YNR035C ARC35; Arc35p\tK05758 ARPC2; actin related protein 2\/3 complex, subunit 2"
					},
					{
						"name":"YLR370C ARC18; Arc18p\tK05756 ARPC3; actin related protein 2\/3 complex, subunit 3"
					},
					{
						"name":"YKL013C ARC19; Arc19p\tK05755 ARPC4; actin related protein 2\/3 complex, subunit 4"
					},
					{
						"name":"YIL062C ARC15; Arc15p\tK05754 ARPC5; actin related protein 2\/3 complex, subunit 5"
					},
					{
						"name":"YDL029W ARP2; actin-related protein 2\tK17260 ACTR2; actin-related protein 2"
					},
					{
						"name":"YJR065C ARP3; actin-related protein 3\tK18584 ACTR3; actin-related protein 3"
					}
					]
				},
				{
					"name":"WASP \/ WAVE",
					"children":[
					{
						"name":"YOR181W LAS17; actin-binding protein LAS17\tK23612 WASL; neural Wiskott-Aldrich syndrome protein"
					}
					]
				},
				{
					"name":"Formins"
				},
				{
					"name":"Profilin",
					"children":[
					{
						"name":"YOR122C PFY1; profilin\tK05759 PFN; profilin"
					}
					]
				},
				{
					"name":"Thymosin"
				},
				{
					"name":"ADF \/ Cofilin",
					"children":[
					{
						"name":"YLL050C COF1; cofilin\tK05765 CFL; cofilin"
					},
					{
						"name":"SCMC complex"
					}
					]
				},
				{
					"name":"Gelsolin \/ villin"
				},
				{
					"name":"Ezrin\/Radixin\/Moesin"
				},
				{
					"name":"Capping proteins",
					"children":[
					{
						"name":"YKL007W CAP1; Cap1p\tK10364 CAPZA; F-actin-capping protein subunit alpha"
					},
					{
						"name":"YIL034C CAP2; F-actin-capping protein subunit beta\tK10365 CAPZB; F-actin-capping protein subunit beta"
					}
					]
				},
				{
					"name":"Tropomyosins",
					"children":[
					{
						"name":"YIL138C TPM2; tropomyosin TPM2\tK17945 TPM1_2; tropomyosin, fungi type"
					},
					{
						"name":"YNL079C TPM1; tropomyosin TPM1\tK17945 TPM1_2; tropomyosin, fungi type"
					}
					]
				},
				{
					"name":"Troponins"
				},
				{
					"name":"Cross-linking proteins",
					"children":[
					{
						"name":"YLR429W CRN1; Crn1p\tK13886 CORO1B_1C_6; coronin-1B\/1C\/6"
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"YOR367W SCP1; Scp1p\tK20526 TAGLN; transgelin"
					},
					{
						"name":"YPL242C IQG1; Iqg1p\tK05767 IQGAP2_3; Ras GTPase-activating-like protein IQGAP2\/3"
					},
					{
						"name":"YIL097W FYV10; glucose-induced degradation complex subunit FYV10\tK18624 MAEA; macrophage erythroblast attacher"
					},
					{
						"name":"YDR129C SAC6; fimbrin\tK17275 PLS1; plastin-1"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Intermediate filaments",
			"children":[
			{
				"name":"Intermediate filaments",
				"children":[
				{
					"name":"Types I and II: Acidic and basic keratins"
				},
				{
					"name":"Type III"
				},
				{
					"name":"Type IV"
				},
				{
					"name":"Type V: Nuclear lamins"
				},
				{
					"name":"Type VI"
				},
				{
					"name":"Others"
				}
				]
			},
			{
				"name":"Intermediate filament-binding proteins"
			}
			]
		},
		{
			"name":"Microtubules",
			"children":[
			{
				"name":"Tubulins",
				"children":[
				{
					"name":"YML085C TUB1; alpha-tubulin TUB1\tK07374 TUBA; tubulin alpha"
				},
				{
					"name":"YML124C TUB3; alpha-tubulin TUB3\tK07374 TUBA; tubulin alpha"
				},
				{
					"name":"YFL037W TUB2; beta-tubulin\tK07375 TUBB; tubulin beta"
				},
				{
					"name":"YLR212C TUB4; gamma-tubulin\tK10389 TUBG; tubulin gamma"
				}
				]
			},
			{
				"name":"Tubulin-binding proteins",
				"children":[
				{
					"name":"Kinesins",
					"children":[
					{
						"name":"YKL079W SMY1; Smy1p\tK10396 KIF5; kinesin family member 5 (plus-end-directed kinesin ATPase) [EC:5.6.1.3]"
					},
					{
						"name":"YBL063W KIP1; Kip1p\tK10398 KIF11; kinesin family member 11"
					},
					{
						"name":"YEL061C CIN8; kinesin motor protein CIN8\tK10398 KIF11; kinesin family member 11"
					},
					{
						"name":"YGL216W KIP3; tubulin-dependent ATPase KIP3\tK10401 KIF18A; kinesin family member 18A"
					},
					{
						"name":"YPR141C KAR3; Kar3p\tK10405 KIFC1; kinesin family member C1 (minus-end-directed kinesin ATPase) [EC:5.6.1.4]"
					}
					]
				},
				{
					"name":"Stathmin"
				},
				{
					"name":"Microtubule severing proteins"
				},
				{
					"name":"EMAP"
				},
				{
					"name":"Dyneins",
					"children":[
					{
						"name":"YKR054C DYN1; dynein heavy chain\tK10413 DYNC1H; dynein cytoplasmic 1 heavy chain"
					},
					{
						"name":"YDR488C PAC11; dynein intermediate chain\tK10415 DYNC1I; dynein cytoplasmic 1 intermediate chain"
					},
					{
						"name":"YDR424C DYN2; dynein light chain\tK10418 DYNLL; dynein light chain LC8-type"
					},
					{
						"name":"Dynein-related proteins"
					}
					]
				},
				{
					"name":"Dynactins",
					"children":[
					{
						"name":"YPL174C NIP100; Nip100p\tK04648 DCTN1; dynactin 1"
					},
					{
						"name":"YMR294W JNM1; Jnm1p\tK18599 JNM1; nuclear migration protein JNM1"
					},
					{
						"name":"YLL049W LDB18; Ldb18p\tK18600 LDB18; potein LDB18"
					}
					]
				},
				{
					"name":"Gamma-tubulin complex components",
					"children":[
					{
						"name":"YHR172W SPC97; Spc97p\tK16569 TUBGCP2; gamma-tubulin complex component 2"
					},
					{
						"name":"YNL126W SPC98; Spc98p\tK16570 TUBGCP3; gamma-tubulin complex component 3"
					}
					]
				},
				{
					"name":"XMAP215",
					"children":[
					{
						"name":"YLR045C STU2; Stu2p\tK24394 STU2; protein STU2"
					}
					]
				},
				{
					"name":"Cytoplasmic linker proteins (CLIPs)",
					"children":[
					{
						"name":"CLIP-associating proteins",
						"children":[
						{
							"name":"YBL034C STU1; Stu1p\tK16578 CLASP1_2; CLIP-associating protein 1\/2"
						}
						]
					}
					]
				},
				{
					"name":"Fused toes protein (FTS)"
				},
				{
					"name":"Hook proteins"
				},
				{
					"name":"FTS and Hook-interacting proteins (FHIP)"
				},
				{
					"name":"EB \/ APC",
					"children":[
					{
						"name":"YER016W BIM1; microtubule-binding protein BIM1\tK10436 MAPRE; microtubule-associated protein, RP\/EB family"
					}
					]
				},
				{
					"name":"Microtubule-associated proteins (MAPs)",
					"children":[
					{
						"name":"YOR058C ASE1; Ase1p\tK16732 PRC1; Ase1\/PRC1\/MAP65 family protein"
					}
					]
				},
				{
					"name":"Tubulin modification proteins",
					"children":[
					{
						"name":"Tubulin polyglutamylases"
					},
					{
						"name":"Tubulin polyglutamylase complex components"
					},
					{
						"name":"Other tubulin modification proteins",
						"children":[
						{
							"name":"YBR094W PBY1; putative tubulin tyrosine ligase\tK06047 TTL; tubulin---tyrosine ligase [EC:6.3.2.25]"
						}
						]
					}
					]
				},
				{
					"name":"Others",
					"children":[
					{
						"name":"YJR008W MHO1; Mho1p\tK06990 MEMO1; MEMO1 family protein"
					},
					{
						"name":"YOR265W RBL2; Rbl2p\tK17292 TBCA; tubulin-specific chaperone A"
					},
					{
						"name":"YNL148C ALF1; Alf1p\tK17262 TBCB; tubulin-specific chaperone B"
					},
					{
						"name":"YPL241C CIN2; GTPase-activating protein CIN2\tK21766 TBCC; tubulin-specific chaperone C"
					},
					{
						"name":"YOR349W CIN1; Cin1p\tK21767 TBCD; tubulin-specific chaperone D"
					},
					{
						"name":"YER007W PAC2; Pac2p\tK21768 TBCE; tubulin-specific chaperone E"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"Septins",
			"children":[
			{
				"name":"Septins",
				"children":[
				{
					"name":"Group 1",
					"children":[
					{
						"name":"YCR002C CDC10; septin CDC10\tK16938 SEPT3_9_12; septin 3\/9\/12"
					}
					]
				},
				{
					"name":"Group 2",
					"children":[
					{
						"name":"YLR314C CDC3; septin CDC3\tK16944 SEPT7; septin 7"
					}
					]
				},
				{
					"name":"Group 3",
					"children":[
					{
						"name":"YJR076C CDC11; septin CDC11\tK16945 CDC11; cell division control protein 11"
					},
					{
						"name":"YDL225W SHS1; septin SHS1\tK16946 SHS1; seventh homolog of septin 1"
					},
					{
						"name":"YDR218C SPR28; septin SPR28\tK16947 SPR28; sporulation-regulated protein 28"
					}
					]
				},
				{
					"name":"Group 4",
					"children":[
					{
						"name":"YHR107C CDC12; septin CDC12\tK16948 CDC12; cell division control protein 12"
					},
					{
						"name":"YGR059W SPR3; septin SPR3\tK12773 SPR3; sporulation-regulated protein 3"
					}
					]
				}
				]
			},
			{
				"name":"Septin associated proteins",
				"children":[
				{
					"name":"YIL140W AXL2; Axl2p\tK18637 AXL2; axial budding pattern protein 2"
				},
				{
					"name":"YNL233W BNI4; Bni4p\tK18638 BNI4; protein BNI4"
				},
				{
					"name":"YKL101W HSL1; protein kinase HSL1\tK02515 HSL1; serine\/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]"
				},
				{
					"name":"YCL024W KCC4; serine\/threonine protein kinase\tK18639 KCC4; serine\/threonine-protein kinase KCC4 [EC:2.7.11.1]"
				},
				{
					"name":"YDR507C GIN4; protein kinase GIN4\tK06668 GIN4; serine\/threonine-protein kinase GIN4 [EC:2.7.11.-]"
				},
				{
					"name":"YDR409W SIZ1; SUMO ligase SIZ1\tK04706 PIAS1; E3 SUMO-protein ligase PIAS1 [EC:2.3.2.-]"
				}
				]
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic cytoskeleton proteins",
		"children":[
		{
			"name":"Actin homologs",
			"children":[
			{
				"name":"Actins"
			},
			{
				"name":"Actin-binding proteins"
			}
			]
		},
		{
			"name":"Intermediate filaments homologs"
		},
		{
			"name":"Microtubules homologs"
		},
		{
			"name":"MinD \/ ParA class of bacterial cytoskeletal proteins"
		}
		]
	}
	]
}