{
	"name":"sita03032",
	"children":[
	{
		"name":"Eukaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"pre-RC (pre-replication complex)",
				"children":[
				{
					"name":"101773091 origin of replication complex subunit 1 isoform X1\tK02603 ORC1; origin recognition complex subunit 1"
				},
				{
					"name":"101767459 origin of replication complex subunit 2\tK02604 ORC2; origin recognition complex subunit 2"
				},
				{
					"name":"101764860 origin of replication complex subunit 3\tK02605 ORC3; origin recognition complex subunit 3"
				},
				{
					"name":"101754353 origin of replication complex subunit 4 isoform X1\tK02606 ORC4; origin recognition complex subunit 4"
				},
				{
					"name":"101780411 origin of replication complex subunit 1\tK02607 ORC5; origin recognition complex subunit 5"
				},
				{
					"name":"101769556 origin of replication complex subunit 6\tK02608 ORC6; origin recognition complex subunit 6"
				},
				{
					"name":"101756609 CDT1-like protein b\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"101758414 CDT1-like protein a, chloroplastic\tK10727 CDT1; chromatin licensing and DNA replication factor 1"
				},
				{
					"name":"101761509 cell division control protein 6 homolog\tK02213 CDC6; cell division control protein 6"
				},
				{
					"name":"101777809 DNA replication licensing factor MCM2\tK02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]"
				},
				{
					"name":"101779306 LOW QUALITY PROTEIN: DNA replication licensing factor MCM3 homolog 2\tK02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]"
				},
				{
					"name":"101760715 DNA replication licensing factor MCM4\tK02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]"
				},
				{
					"name":"101754382 DNA replication licensing factor MCM5\tK02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]"
				},
				{
					"name":"101761710 DNA replication licensing factor MCM6\tK02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]"
				},
				{
					"name":"101770663 DNA replication licensing factor MCM7\tK02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]"
				}
				]
			},
			{
				"name":"CDK (cyclin dependent kinase)",
				"children":[
				{
					"name":"101759204 cyclin-A1-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101761211 cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101762128 cyclin-A1-4\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101763113 cyclin-A3-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101766474 cyclin-A3-2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101772935 cyclin-A2-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101776082 cyclin-A2-1\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101786164 cyclin-A1-3 isoform X2\tK06627 CCNA; cyclin-A"
				},
				{
					"name":"101758525 cell division control protein 2 homolog\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				},
				{
					"name":"101771773 cyclin-dependent kinase A-2\tK02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]"
				}
				]
			},
			{
				"name":"DDK (Dbf-4 dependent kinase)",
				"children":[
				{
					"name":"101767316 probable serine\/threonine-protein kinase cdc7\tK02214 CDC7; cell division control protein 7 [EC:2.7.11.1]"
				}
				]
			},
			{
				"name":"GINS complex",
				"children":[
				{
					"name":"101767162 DNA replication complex GINS protein PSF1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"101770716 DNA replication complex GINS protein PSF1 isoform X1\tK10732 GINS1; GINS complex subunit 1"
				},
				{
					"name":"101753461 DNA replication complex GINS protein PSF2\tK10733 GINS2; GINS complex subunit 2"
				},
				{
					"name":"101773701 DNA replication complex GINS protein PSF3 isoform X2\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"111257693 DNA replication complex GINS protein PSF3-like\tK10734 GINS3; GINS complex subunit 3"
				},
				{
					"name":"101779197 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				},
				{
					"name":"101781974 DNA replication complex GINS protein SLD5\tK10735 GINS4; GINS complex subunit 4"
				}
				]
			},
			{
				"name":"Other initiation factors",
				"children":[
				{
					"name":"101767409 LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"101775152 BRCT domain-containing protein At4g02110 isoform X2\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"101778601 BRCT domain-containing protein At4g02110\tK10728 TOPBP1; topoisomerase (DNA) II binding protein 1"
				},
				{
					"name":"101773995 ATP-dependent DNA helicase Q-like 5\tK10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]"
				},
				{
					"name":"101756431 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"101769438 cell division control protein 45 homolog\tK06628 CDC45; cell division control protein 45"
				},
				{
					"name":"101769172 probable DNA helicase MCM8 isoform X1\tK10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]"
				},
				{
					"name":"101780408 probable DNA helicase MCM9 isoform X2\tK10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]"
				},
				{
					"name":"101783037 protein MCM10 homolog\tK10736 MCM10; minichromosome maintenance protein 10"
				},
				{
					"name":"101786066 mini-chromosome maintenance complex-binding protein\tK28390 MCMBP; minichromosome maintenance complex-binding protein"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"DNA polymerase alpha \/ primase complex",
				"children":[
				{
					"name":"101761388 DNA polymerase alpha catalytic subunit\tK02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]"
				},
				{
					"name":"101775496 DNA polymerase alpha subunit B\tK02321 POLA2; DNA polymerase alpha subunit B"
				},
				{
					"name":"101770356 DNA primase small subunit\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"101774297 DNA primase small subunit\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"101778365 DNA primase small subunit\tK02684 PRI1; DNA primase small subunit [EC:2.7.7.102]"
				},
				{
					"name":"101767260 probable DNA primase large subunit\tK02685 PRI2; DNA primase large subunit"
				}
				]
			},
			{
				"name":"DNA polymerase epsilon complex",
				"children":[
				{
					"name":"101780569 DNA polymerase epsilon catalytic subunit A\tK02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"101756279 DNA polymerase epsilon subunit B\tK02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]"
				},
				{
					"name":"101760620 DNA polymerase epsilon subunit 3\tK02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]"
				}
				]
			},
			{
				"name":"DNA polymerase delta complex",
				"children":[
				{
					"name":"101765223 DNA polymerase delta catalytic subunit\tK02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]"
				},
				{
					"name":"101758255 DNA polymerase delta small subunit\tK02328 POLD2; DNA polymerase delta subunit 2"
				},
				{
					"name":"101752597 protein IWS1 homolog A\tK03504 POLD3; DNA polymerase delta subunit 3"
				},
				{
					"name":"101773431 DNA polymerase delta subunit 4 isoform X2\tK03505 POLD4; DNA polymerase delta subunit 4"
				},
				{
					"name":"101781643 DNA polymerase delta subunit 4\tK03505 POLD4; DNA polymerase delta subunit 4"
				}
				]
			},
			{
				"name":"DNA polymerase gamma complex (mitochondrial)"
			},
			{
				"name":"RPA (replication protein A)",
				"children":[
				{
					"name":"101769391 replication protein A 70 kDa DNA-binding subunit A\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"101773875 replication protein A 70 kDa DNA-binding subunit C\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"101774060 replication protein A 70 kDa DNA-binding subunit B\tK07466 RFA1; replication factor A1"
				},
				{
					"name":"101762458 LOW QUALITY PROTEIN: replication protein A 32 kDa subunit C-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"101763151 LOW QUALITY PROTEIN: replication protein A 32 kDa subunit B-like\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"101766440 replication protein A 32 kDa subunit A isoform X2\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"101786380 replication protein A 32 kDa subunit A\tK10739 RFA2; replication factor A2"
				},
				{
					"name":"101767472 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
				},
				{
					"name":"101783898 replication protein A 14 kDa subunit\tK10740 RPA3; replication factor A3"
				}
				]
			},
			{
				"name":"RFC (replication factor C)",
				"children":[
				{
					"name":"101777540 replication factor C subunit 1\tK10754 RFC1; replication factor C subunit 1"
				},
				{
					"name":"101771026 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"101780069 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"101753640 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"101758264 uncharacterized protein LOC101758264\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"101766280 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"RNase H",
				"children":[
				{
					"name":"101766032 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"101786406 ribonuclease H2 subunit A\tK10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]"
				},
				{
					"name":"101784643 ribonuclease H2 subunit B\tK10744 RNASEH2B; ribonuclease H2 subunit B"
				},
				{
					"name":"101759764 ribonuclease H2 subunit C\tK10745 RNASEH2C; ribonuclease H2 subunit C"
				}
				]
			},
			{
				"name":"Other elongation factors",
				"children":[
				{
					"name":"101771789 proliferating cell nuclear antigen\tK04802 PCNA; proliferating cell nuclear antigen"
				},
				{
					"name":"101781823 DNA replication ATP-dependent helicase\/nuclease DNA2 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
				},
				{
					"name":"101757814 flap endonuclease 1-B isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"101764565 flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
				},
				{
					"name":"101771049 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"101786871 exonuclease 1\tK10746 EXO1; exonuclease 1 [EC:3.1.-.-]"
				},
				{
					"name":"101760767 DNA annealing helicase and endonuclease ZRANB3 isoform X1\tK25861 ZRANB3; DNA annealing helicase and endonuclease ZRANB3 [EC:5.6.2.- 3.1.-.-]"
				},
				{
					"name":"101778667 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
				},
				{
					"name":"101753390 LOW QUALITY PROTEIN: uncharacterized protein LOC101753390\tK26118 ATAD5; ATPase family AAA domain-containing protein 5"
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"DNA methylation enzymes",
				"children":[
				{
					"name":"101755233 DNA (cytosine-5)-methyltransferase CMT2 isoform X1\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"101757301 DNA (cytosine-5)-methyltransferase 1A\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"101774591 DNA (cytosine-5)-methyltransferase 3\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"101776623 DNA (cytosine-5)-methyltransferase CMT1-like\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"101778313 DNA (cytosine-5)-methyltransferase 1B\tK00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]"
				},
				{
					"name":"101781565 actin cytoskeleton-regulatory complex protein PAN1 isoform X1\tK17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]"
				}
				]
			},
			{
				"name":"Prevention of re-replication factors",
				"children":[
				{
					"name":"101753254 cyclin-SDS-like\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"101758449 cyclin-B2-1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"101768144 cyclin-B1-3\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"101772257 cyclin-B1-5\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"101779736 cyclin-B2-2\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				},
				{
					"name":"106804318 cyclin-B1-1 isoform X1\tK21777 CCNB; G2\/mitotic-specific cyclin-B, other"
				}
				]
			},
			{
				"name":"Telomere proteins",
				"children":[
				{
					"name":"Shelterin complex",
					"children":[
					{
						"name":"101754071 uncharacterized protein LOC101754071\tK11111 TERF2; telomeric repeat-binding factor 2"
					}
					]
				},
				{
					"name":"TERB1-TERB2-MAJIN complex"
				},
				{
					"name":"CST complex (animals)",
					"children":[
					{
						"name":"101756218 CST complex subunit STN1\tK23312 STN1; CST complex subunit STN1"
					},
					{
						"name":"101774916 CST complex subunit TEN1\tK23313 TEN1; CST complex subunit TEN1"
					}
					]
				},
				{
					"name":"CST complex (yeast)"
				},
				{
					"name":"RIF proteins"
				},
				{
					"name":"SIR proteins"
				}
				]
			},
			{
				"name":"Telomerase complex (animals)",
				"children":[
				{
					"name":"101769857 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Dyskerin complex",
					"children":[
					{
						"name":"101783998 putative H\/ACA ribonucleoprotein complex subunit 1-like protein 1\tK11128 GAR1; H\/ACA ribonucleoprotein complex subunit 1"
					},
					{
						"name":"101766363 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"101784496 H\/ACA ribonucleoprotein complex subunit 2-like protein\tK11129 NHP2; H\/ACA ribonucleoprotein complex subunit 2"
					},
					{
						"name":"101761770 H\/ACA ribonucleoprotein complex subunit 4\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					},
					{
						"name":"101785718 H\/ACA ribonucleoprotein complex subunit 4\tK11131 DKC1; H\/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]"
					}
					]
				}
				]
			},
			{
				"name":"Telomerase complex (fungi)",
				"children":[
				{
					"name":"101769857 telomerase reverse transcriptase isoform X1\tK11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]"
				},
				{
					"name":"Sm core complex",
					"children":[
					{
						"name":"101764245 small nuclear ribonucleoprotein-associated protein B\tK11086 SNRPB; small nuclear ribonucleoprotein B and B'"
					},
					{
						"name":"101753973 small nuclear ribonucleoprotein SmD1a-like\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"101769681 small nuclear ribonucleoprotein SmD1a\tK11087 SNRPD1; small nuclear ribonucleoprotein D1"
					},
					{
						"name":"101753289 small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"101757502 small nuclear ribonucleoprotein Sm D2 isoform X1\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"101773205 small nuclear ribonucleoprotein Sm D2\tK11096 SNRPD2; small nuclear ribonucleoprotein D2"
					},
					{
						"name":"101760317 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"101782551 small nuclear ribonucleoprotein SmD3b\tK11088 SNRPD3; small nuclear ribonucleoprotein D3"
					},
					{
						"name":"101786093 small nuclear ribonucleoprotein E\tK11097 SNRPE; small nuclear ribonucleoprotein E"
					},
					{
						"name":"101769645 probable small nuclear ribonucleoprotein F\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"101776784 probable small nuclear ribonucleoprotein F isoform X1\tK11098 SNRPF; small nuclear ribonucleoprotein F"
					},
					{
						"name":"101752518 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					},
					{
						"name":"101770011 probable small nuclear ribonucleoprotein G\tK11099 SNRPG; small nuclear ribonucleoprotein G"
					}
					]
				}
				]
			},
			{
				"name":"ELG1-RFC complex",
				"children":[
				{
					"name":"101771026 replication factor C subunit 4\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"101780069 replication factor C subunit 2\tK10755 RFC2_4; replication factor C subunit 2\/4"
				},
				{
					"name":"101753640 replication factor C subunit 5\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"101758264 uncharacterized protein LOC101758264\tK10756 RFC3_5; replication factor C subunit 3\/5"
				},
				{
					"name":"101766280 replication factor C subunit 3\tK10756 RFC3_5; replication factor C subunit 3\/5"
				}
				]
			},
			{
				"name":"MRN complex",
				"children":[
				{
					"name":"101758017 double-strand break repair protein MRE11\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"101776820 double-strand break repair protein MRE11 isoform X1\tK10865 MRE11; double-strand break repair protein MRE11"
				},
				{
					"name":"101763296 DNA repair protein RAD50\tK10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]"
				},
				{
					"name":"101763098 nijmegen breakage syndrome 1 protein\tK10867 NBN; nibrin"
				}
				]
			},
			{
				"name":"Other termination factors",
				"children":[
				{
					"name":"101786621 serine\/threonine-protein kinase ATM isoform X1\tK04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]"
				},
				{
					"name":"101776716 ATP-dependent DNA helicase Q-like SIM isoform X1\tK10900 WRN; werner syndrome ATP-dependent helicase [EC:5.6.2.4]"
				},
				{
					"name":"101759362 ATP-dependent DNA helicase Q-like 4A\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"101780443 ATP-dependent DNA helicase Q-like 3 isoform X1\tK10901 BLM; bloom syndrome protein [EC:5.6.2.4]"
				},
				{
					"name":"101771882 DNA repair endonuclease UVH1\tK10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]"
				},
				{
					"name":"101786800 poly [ADP-ribose] polymerase 1\tK24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]"
				},
				{
					"name":"101778678 poly [ADP-ribose] polymerase 2\tK28005 PARP2; poly [ADP-ribose] polymerase 2 [EC:2.4.2.30]"
				},
				{
					"name":"101769619 PIN2\/TERF1-interacting telomerase inhibitor 1\tK11135 PINX1; Pin2-interacting protein X1"
				},
				{
					"name":"101755435 regulator of telomere elongation helicase 1 isoform X1\tK11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]"
				},
				{
					"name":"101782462 telomere length regulation protein TEL2 homolog\tK11137 TELO2; telomere length regulation protein"
				},
				{
					"name":"101785801 transcription factor Pur-alpha 1 isoform X2\tK21772 PURA; transcriptional activator protein Pur-alpha"
				},
				{
					"name":"101759300 telomerase Cajal body protein 1\tK23314 WRAP53; telomerase Cajal body protein 1"
				},
				{
					"name":"101785140 protein SDE2 homolog\tK25059 SDE2; replication stress response regulator SDE2"
				},
				{
					"name":"101785115 protein RTF2 homolog\tK25186 RTF2; replication termination factor 2"
				}
				]
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"101774107 DNA topoisomerase 1 beta isoform X1\tK03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]"
			},
			{
				"name":"101760596 DNA topoisomerase 2 isoform X2\tK03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]"
			},
			{
				"name":"101752849 DNA topoisomerase 3-alpha\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			},
			{
				"name":"101759257 DNA topoisomerase 3-beta isoform X1\tK03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]"
			}
			]
		}
		]
	},
	{
		"name":"Prokaryotic type",
		"children":[
		{
			"name":"DNA Replication Initiation Factors",
			"children":[
			{
				"name":"Initiation factors (bacterial)",
				"children":[
				{
					"name":"101782984 single-stranded DNA-binding protein, mitochondrial\tK03111 ssb; single-strand DNA-binding protein"
				}
				]
			},
			{
				"name":"Initiation factors (archaeal)"
			}
			]
		},
		{
			"name":"DNA Replication Elongation Factors",
			"children":[
			{
				"name":"Elongation factors (bacterial)",
				"children":[
				{
					"name":"DNA polymerase III holoenzyme"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"101760461 DNA polymerase I A, chloroplastic\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					},
					{
						"name":"101784259 DNA polymerase I A, chloroplastic\tK02335 polA; DNA polymerase I [EC:2.7.7.7]"
					}
					]
				}
				]
			},
			{
				"name":"Elongation factors (archaeal)",
				"children":[
				{
					"name":"B-family DNA polymerases"
				},
				{
					"name":"D-family DNA polymerases"
				},
				{
					"name":"RNase H"
				},
				{
					"name":"RFC (replication factor C)"
				},
				{
					"name":"Other elongation factors",
					"children":[
					{
						"name":"101781823 DNA replication ATP-dependent helicase\/nuclease DNA2 isoform X1\tK10742 DNA2; DNA replication ATP-dependent helicase\/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]"
					},
					{
						"name":"101757814 flap endonuclease 1-B isoform X1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"101764565 flap endonuclease 1\tK04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]"
					},
					{
						"name":"101778667 DNA ligase 1\tK10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]"
					}
					]
				}
				]
			}
			]
		},
		{
			"name":"DNA Replication Termination Factors",
			"children":[
			{
				"name":"Terminus site-binding protein"
			},
			{
				"name":"DNA methylation enzymes"
			},
			{
				"name":"Prevention of re-replication factors"
			}
			]
		},
		{
			"name":"DNA Topoisomerases",
			"children":[
			{
				"name":"101785761 probable DNA gyrase subunit A, chloroplastic\/mitochondrial\tK02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]"
			},
			{
				"name":"101761896 DNA gyrase subunit B, chloroplastic\/mitochondrial\tK02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]"
			},
			{
				"name":"101769014 DNA topoisomerase 6 subunit B\tK03167 top6B; DNA topoisomerase VI subunit B [EC:5.6.2.2]"
			}
			]
		}
		]
	}
	]
}